RetrogeneDB ID: retro_ggor_2215

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 5:135229908..135230248(+)
• Located in intron of: ENSGGOG00000004915

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ATP6V1G1
• Ensembl ID: ENSGGOG00000004011
• Aliases: None
• Description: None

Sequence

>retro_ggor_2215
AGCCAGTCTCAGGGGATCCAGCAGCTGCTGCAGGCCAAGAAGCAGCCACTGAGAAGGTGTCCAAGTGTGAACAAAAACAT
AGAGGCTGAAGCAGGCCAAGGAAGCAGCTGAGGCTGAAACTGAACAGCACTGCCTGCAGAGGGAGAAAGAGTTCAAGACC
AAGGAAGCTGCAGCCCTGGAATCTCACAGCAGCCTTGGCACTGAAGTGGCACAGGAGGGTCAGAAGAAGAGGACCAGCCT
CCAGAACTACTTCCAGCAGAATGGGGGTGAAGGCTTGGCTAGCCTCTTGGCTTTTGTCTGTGACACCTGGACAGAAATCC
ATGAAAACTGCTGCATAAAT

Alignment

ORF - retro_ggor_2215 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 65.81 %
• Parental protein coverage: 97.46 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  SQSQGIQQLLQAEKR-AAEKVSEARKRKNR-RLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSRGSCS
          SQSQGIQQLLQA.K..A.EKVS.....K.R.RLKQAKE.A.AE.EQ..LQREKEFK.KEAAAL.S..S..
Retrocopy SQSQGIQQLLQAKKQ<ATEKVSKC-EQKHR<RLKQAKEAAEAETEQHCLQREKEFKTKEAAALESHSSLG

Parental  TEVEKETQEKMTILQTYFRQNRDEVLDNLLAFVCDIRPEIHENYRIN
          TEV..E.Q.K.T.LQ.YF.QN..E.L..LLAFVCD...EIHEN..IN
Retrocopy TEVAQEGQKKRTSLQNYFQQNGGEGLASLLAFVCDTWTEIHENCCIN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	53.52 RPM
SRP007412_cerebellum	0.08 RPM	34.75 RPM
SRP007412_heart	0.00 RPM	14.73 RPM
SRP007412_kidney	0.74 RPM	99.85 RPM
SRP007412_liver	0.00 RPM	31.73 RPM
SRP007412_testis	0.31 RPM	86.20 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2215 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2215 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Macaca mulatta	retro_mmul_2046
Callithrix jacchus	retro_cjac_1788

---

Parental genes homology:

Parental genes homology involve 16 parental genes, and 61 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000020461	3 retrocopies	retro_cjac_1788, retro_cjac_2513, retro_cjac_76,
Dasypus novemcinctus	ENSDNOG00000008083	15 retrocopies	retro_dnov_1173, retro_dnov_1447, retro_dnov_1475, retro_dnov_1504, retro_dnov_1588, retro_dnov_1645, retro_dnov_193, retro_dnov_1998, retro_dnov_2179, retro_dnov_218, retro_dnov_2416, retro_dnov_245, retro_dnov_336, retro_dnov_479, retro_dnov_790,
Dipodomys ordii	ENSDORG00000014850	5 retrocopies	retro_dord_434, retro_dord_466, retro_dord_614, retro_dord_640, retro_dord_749,
Echinops telfairi	ENSETEG00000008080	3 retrocopies	retro_etel_350, retro_etel_594, retro_etel_996,
Homo sapiens	ENSG00000136888	3 retrocopies	retro_hsap_3198, retro_hsap_4049, retro_hsap_763,
Gorilla gorilla	ENSGGOG00000004011	4 retrocopies	retro_ggor_1331, retro_ggor_2215 , retro_ggor_2717, retro_ggor_632,
Loxodonta africana	ENSLAFG00000013437	2 retrocopies	retro_lafr_1002, retro_lafr_39,
Myotis lucifugus	ENSMLUG00000008657	2 retrocopies	retro_mluc_373, retro_mluc_839,
Macaca mulatta	ENSMMUG00000004899	4 retrocopies	retro_mmul_1783, retro_mmul_2018, retro_mmul_2046, retro_mmul_331,
Monodelphis domestica	ENSMODG00000019574	1 retrocopy	retro_mdom_1675,
Mus musculus	ENSMUSG00000039105	5 retrocopies	retro_mmus_2028, retro_mmus_2784, retro_mmus_2787, retro_mmus_3316, retro_mmus_819,
Nomascus leucogenys	ENSNLEG00000016833	2 retrocopies	retro_nleu_1151, retro_nleu_3045,
Pan troglodytes	ENSPTRG00000021290	2 retrocopies	retro_ptro_2248, retro_ptro_2744,
Ictidomys tridecemlineatus	ENSSTOG00000015857	5 retrocopies	retro_itri_1102, retro_itri_1235, retro_itri_1281, retro_itri_1340, retro_itri_1669,
Tupaia belangeri	ENSTBEG00000010985	2 retrocopies	retro_tbel_2147, retro_tbel_786,
Tarsius syrichta	ENSTSYG00000011474	3 retrocopies	retro_tsyr_1865, retro_tsyr_2141, retro_tsyr_614,