RetrogeneDB ID: retro_pabe_1875

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 22:18047571..18047849(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ATP5J
• Ensembl ID: ENSPPYG00000011305
• Aliases: None
• Description: ATP synthase-coupling factor 6, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:Q5RBY3]

Sequence

>retro_pabe_1875
AGCAGTCTCAGTCCATTTGCGGAGGAACATCAGTGTTACACAGCAGTGGCATTTAATAAGGAACTTGATCCTATACAGAA
ACTCTTGTGGACAAGATTAGAGAATACAAATTGAAGTGACAGACATCTGGAGGACCTGTTGATACTGGTCCAGAGTATCA
GCAAGAGCTGGAGAGGGAGATTTTTAAGTTCAAGCAAATGTTTGGTAAAACAGACATGAATACATTTCCCAACTTCAAAT
TTGAAGATCCCAAATCTGAAGTCATCAAAAAACCCCAG

Alignment

ORF - retro_pabe_1875 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.47 %
• Parental protein coverage: 86.92 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  SAVSVYLRRNIGVTAVAFNKELDPIQKLF-VDKIREYKSKRQTSGGPVDAGPEYQQELEKELFKLKQMFG
          S..S.........TAVAFNKELDPIQKL..VDKIREYK.K.QTSGGPVD.GPEYQQELE.E.FK.KQMFG
Retrocopy SSLSPFAEEHQCYTAVAFNKELDPIQKLL<VDKIREYKLK*QTSGGPVDTGPEYQQELEREIFKFKQMFG

Parental  NADMNTFPAFKFEDPKFEVIEKPQ
          ..DMNTFP.FKFEDPK.EVI.KPQ
Retrocopy KTDMNTFPNFKFEDPKSEVIKKPQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	39.98 RPM
SRP007412_cerebellum	0.00 RPM	44.26 RPM
SRP007412_heart	0.09 RPM	91.00 RPM
SRP007412_kidney	0.03 RPM	60.33 RPM
SRP007412_liver	0.00 RPM	47.43 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_1875 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_1875 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_1875 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2548
Pan troglodytes	retro_ptro_1485
Gorilla gorilla	retro_ggor_1593

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 41 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000017167	1 retrocopy	retro_amel_1858,
Bos taurus	ENSBTAG00000000605	1 retrocopy	retro_btau_1653,
Canis familiaris	ENSCAFG00000024922	2 retrocopies	retro_cfam_1664, retro_cfam_1993,
Callithrix jacchus	ENSCJAG00000013803	3 retrocopies	retro_cjac_1531, retro_cjac_2559, retro_cjac_665,
Equus caballus	ENSECAG00000017858	2 retrocopies	retro_ecab_548, retro_ecab_644,
Erinaceus europaeus	ENSEEUG00000011228	2 retrocopies	retro_eeur_693, retro_eeur_695,
Echinops telfairi	ENSETEG00000006438	4 retrocopies	retro_etel_1847, retro_etel_2218, retro_etel_468, retro_etel_832,
Felis catus	ENSFCAG00000029970	1 retrocopy	retro_fcat_1451,
Homo sapiens	ENSG00000154723	3 retrocopies	retro_hsap_2548, retro_hsap_3990, retro_hsap_4920,
Gorilla gorilla	ENSGGOG00000008265	2 retrocopies	retro_ggor_1593, retro_ggor_2678,
Myotis lucifugus	ENSMLUG00000015988	1 retrocopy	retro_mluc_1266,
Macaca mulatta	ENSMMUG00000008725	1 retrocopy	retro_mmul_2306,
Monodelphis domestica	ENSMODG00000021011	1 retrocopy	retro_mdom_1010,
Mustela putorius furo	ENSMPUG00000001001	2 retrocopies	retro_mputfur_1573, retro_mputfur_1582,
Nomascus leucogenys	ENSNLEG00000002412	1 retrocopy	retro_nleu_539,
Oryctolagus cuniculus	ENSOCUG00000006681	5 retrocopies	retro_ocun_1517, retro_ocun_1888, retro_ocun_326, retro_ocun_419, retro_ocun_789,
Pongo abelii	ENSPPYG00000011305	2 retrocopies	retro_pabe_1874, retro_pabe_1875 ,
Pan troglodytes	ENSPTRG00000013809	3 retrocopies	retro_ptro_1485, retro_ptro_2708, retro_ptro_3312,
Sorex araneus	ENSSARG00000000742	3 retrocopies	retro_sara_165, retro_sara_225, retro_sara_501,
Sus scrofa	ENSSSCG00000022586	1 retrocopy	retro_sscr_896,