miRNEST 2.0: an integrative microRNA resource miRNEST 2.0, an integrative microRNA resource :: Browse

Species belonging to selected taxon:

Mus musculus, Sus scrofa, Bos taurus, Danio rerio, Rattus norvegicus, Xenopus laevis, Oryzias latipes, Gallus gallus, Salmo salar, Canis lupus familiaris, Ictalurus punctatus, Ovis aries, Oncorhynchus mykiss, Gasterosteus aculeatus, Pimephales promelas, Gadus morhua, Macaca fascicularis, Anolis carolinensis, Trichosurus vulpecula, Papio anubis, Ictalurus furcatus, Homo sapiens, Petromyzon marinus, Oreochromis niloticus, Taeniopygia guttata, Peromyscus maniculatus bairdii, Fundulus heteroclitus, Sparus aurata, Dicentrarchus labrax, Pongo abelii, Ursus americanus, Equus caballus, Dissostichus mawsoni, Osmerus mordax, Oryctolagus cuniculus, Macaca nemestrina, Anoplopoma fimbria, Cyprinus carpio, Esox lucius, Squalus acanthias, Leucoraja erinacea, Rana catesbeiana, Takifugu rubripes, Cynops pyrrhogaster, Eptatretus burgeri, Sebastes caurinus, Misgurnus anguillicaudatus, Perca flavescens, Paralabidochromis chilotes, Hippoglossus hippoglossus, Ambystoma tigrinum tigrinum, Cavia porcellus, Bos indicus, Rutilus rutilus, Meleagris gallopavo, Lonchura striata domestica, Poecilia reticulata, Bos sp., Macropus eugenii, Peromyscus polionotus subgriseus, Oncorhynchus tshawytscha, Capra hircus, Paralichthys olivaceus, Psetta maxima, Pan troglodytes verus, Lates calcarifer, Oncorhynchus nerka, Sebastes rastrelliger, Thymallus thymallus, Solea senegalensis, Coregonus clupeaformis, Torpedo californica, Thunnus thynnus, Cynoglossus semilaevis, Salvelinus fontinalis, Macaca mulatta



ABOUT THIS RECORD

ID: MNEST032647
species: Rattus norvegicus
miRNA family: let-7
source: miRBase, original name: rno-let-7i (MI0000835)

Taxonomy by NCBI:
Rattus norvegicus Rattus Murinae Muridae Muroidea Sciurognathi Rodentia Glires Euarchontoglires Eutheria Theria Mammalia Amniota Tetrapoda Sarcopterygii Euteleostomi Teleostomi Gnathostomata Vertebrata Craniata Chordata Deuterostomia Coelomata Bilateria Eumetazoa Metazoa Fungi/Metazoa group Eukaryota cellular organisms






SEQUENCE & STRUCTURE
miRNA
TGAGGTAGTAGTTTGTGCTGTT

miRNA*
CTGCGCAAGCTACTGCCTTGCT

mismatches: 2
bulges: 0

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pre-miRNA
CTGGCTGAGGTAGTAGTTTGTGCTGTTGGTCGGGTTGTGACATTGCCCGCTGTGGAGATAACTGCGCAAGCTACTGCCTTGCTAG

dot-bracket secondary structure
(((((.(((((((((((((((((.(((((.(((((.........)))))))........))).))))))))))))))))))))))


SIMILARITIES
miRBase tgu-let-7i: 4e-43

PMRD no hits

microPC no hits
UniProt no hits

RFAM let-7: 6e-30

Identical with: mmu-let-7i from miRBase (MNEST031762)

MORE

miRNEST target predictions: none
non-miRNEST targets
HuntMi prediction: true miRNA
additional data
download this record
evidence: cloned, SOLiD

references

[1] Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR, Genome Biol. 5:R68(2004)., "Microarray analysis of microRNA expression in the developing mammalian brain"
[2] Linsen SE, de Wit E, de Bruijn E, Cuppen E, BMC Genomics. 11:249(2010)., "Small RNA expression and strain specificity in the rat"
[3] Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M, Cell. 129:1401-1414(2007)., "A mammalian microRNA expression atlas based on small RNA library sequencing"
[4] Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G, Proc Natl Acad Sci U S A. 101:360-365(2004)., "Identification of many microRNAs that copurify with polyribosomes in mammalian neurons"
[5] He X, Zhang Q, Liu Y, Pan X, Acta Biochim Biophys Sin (Shanghai). 39:708-714(2007)., "Cloning and identification of novel microRNAs from rat hippocampus"
[6] Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H, Genes Dev. 20:1732-1743(2006)., "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes"




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