RetrogeneDB ID: retro_chof_2393

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_70995:5398..6122(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ATP1B3
• Ensembl ID: ENSCHOG00000007515
• Aliases: None
• Description: ATPase, Na+/K+ transporting, beta 3 polypeptide [Source:HGNC Symbol;Acc:806]

Sequence

>retro_chof_2393
TTGATCTTGCTCTTCTACCCAGTCTTCTATGAGCTCCTGGCTGCACTCTGCACGTTCACAGTGTGGGTCATGCTTCAGAC
TTTGAACGGCGAGCTTCCAAAATATCGTGACCAGATTCCTAGTTCAGGACTTACGGTTTTTCCAGAACCATTTACTGCAT
TGGAATATACAATCAGTTTGTCTGATTCAGGCTCCTATAAAGCATACATTGAAGACCTTACTAGTTTTCTAAAGCCATAT
GATTTAGAAGAACGGAGGAATCTCACAGTCTGTCCTGATGGAGTACTTTTTGAACAGAAGGGCCCAGATTATCAGGCATG
TCAGTTTCCTGTTCACTTACTTGAAGAATGCAGTGGTAGGAGAGATCCTGATTTTGGCTATTCCAGAGGAAAACCTTGTG
TTCTTGTGAAAATGAACAGAGTAATTGCATTAAAGCTTGAAGGAAAACCAAGGATAATGTGTGTTCCCAAGAATGGAAAC
ACTACAGTTTTATCAATTTATCCTTGCAATGGAATTGTAGACTTAAAATATTTTCCATATTATGGAAAAAATTGCATGTG
GGATATTTACAGCCAGTAGTTGCTGTCCAGCCAGTCTTTATCTTTAACAGCACCAAGAAAAAGTGACAGCTGAGTGCAAG
ATTGCTGGGGCACCCAACCTAAAAAGCCAGGATGATCGCAACAAGTTTTTGGGATGAGTTGTGTTCAAAATCACAGTGAA
TGCA

Alignment

ORF - retro_chof_2393 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.2 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  LILLFYLVFYGFLAALFTFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPFTALEYTISLSDSGSYKAYV
          LILLFY.VFY..LAAL.TFT.WVMLQTLN.E.PKYRDQIPS.GL.VFP.PFTALEYTISLSDSGSYKAY.
Retrocopy LILLFYPVFYELLAALCTFTVWVMLQTLNGELPKYRDQIPSSGLTVFPEPFTALEYTISLSDSGSYKAYI

Parental  EDLTNFLKP-NVVEQKNLTVCPDGALFEQKGPDYHACQFPVHLLEECSGMRDPDFGYSKGKPCVLVKMNR
          EDLT.FLKP....E..NLTVCPDG.LFEQKGPDY.ACQFPVHLLEECSG.RDPDFGYS.GKPCVLVKMNR
Retrocopy EDLTSFLKPYDLEERRNLTVCPDGVLFEQKGPDYQACQFPVHLLEECSGRRDPDFGYSRGKPCVLVKMNR

Parental  IIGLKPEGEPRIMCVPKDGNTAVLSTYPHNGIVDLKYFPYYG-KKLHVGYLQPVVAVQPVFSSNSTKK-E
          .I.LK.EG.PRIMCVPK.GNT.VLS.YP.NGIVDLKYFPYYG.KKLHVGYLQPVVAVQPVF..NSTKK..
Retrocopy VIALKLEGKPRIMCVPKNGNTTVLSIYPCNGIVDLKYFPYYG<KKLHVGYLQPVVAVQPVFIFNSTKK<K

Parental  TTVECKIDGSPNLKSQDDRDKFLGRVVFKITVNA
          .T.ECKI.G.PNLKSQDDR.KFLG.VVFKITVNA
Retrocopy VTAECKIAGAPNLKSQDDRNKFLG*VVFKITVNA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2393 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 36 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000014140	5 retrocopies	retro_btau_1136, retro_btau_1322, retro_btau_1743, retro_btau_318, retro_btau_920,
Choloepus hoffmanni	ENSCHOG00000007515	4 retrocopies	retro_chof_1000, retro_chof_1421, retro_chof_2393 , retro_chof_2445,
Callithrix jacchus	ENSCJAG00000001981	1 retrocopy	retro_cjac_309,
Cavia porcellus	ENSCPOG00000003739	4 retrocopies	retro_cpor_1181, retro_cpor_1468, retro_cpor_1506, retro_cpor_222,
Equus caballus	ENSECAG00000019885	2 retrocopies	retro_ecab_1084, retro_ecab_468,
Homo sapiens	ENSG00000069849	2 retrocopies	retro_hsap_1387, retro_hsap_2263,
Loxodonta africana	ENSLAFG00000010553	1 retrocopy	retro_lafr_815,
Mus musculus	ENSMUSG00000032412	2 retrocopies	retro_mmus_2174, retro_mmus_3427,
Nomascus leucogenys	ENSNLEG00000004663	1 retrocopy	retro_nleu_1286,
Otolemur garnettii	ENSOGAG00000008662	1 retrocopy	retro_ogar_2284,
Procavia capensis	ENSPCAG00000013927	1 retrocopy	retro_pcap_350,
Pongo abelii	ENSPPYG00000014169	1 retrocopy	retro_pabe_1953,
Pan troglodytes	ENSPTRG00000015476	2 retrocopies	retro_ptro_1603, retro_ptro_951,
Rattus norvegicus	ENSRNOG00000011501	2 retrocopies	retro_rnor_2571, retro_rnor_789,
Sus scrofa	ENSSSCG00000011676	3 retrocopies	retro_sscr_889, retro_sscr_945, retro_sscr_95,
Ictidomys tridecemlineatus	ENSSTOG00000013235	1 retrocopy	retro_itri_1663,
Tupaia belangeri	ENSTBEG00000001004	1 retrocopy	retro_tbel_3620,
Tarsius syrichta	ENSTSYG00000000222	1 retrocopy	retro_tsyr_330,
Tursiops truncatus	ENSTTRG00000012038	1 retrocopy	retro_ttru_333,