RetrogeneDB ID: retro_ggor_1234

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 16:38138504..38139634(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000026977
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: MOCS1
• Ensembl ID: ENSGGOG00000008943
• Aliases: None
• Description: None

Sequence

>retro_ggor_1234
TCCCGGATGCTGCGCCGGCTCCTAAGGTCCAACGCCACGGAGCTGCAGCTCACGGGTTCCGGTGATGCCACCCCGCCCGG
GCGAGTCCCTGCAAGCTGCCTCACAGGAGCTGTCCAGGCGGAGGCAGTTCTCGCGGGAGCACGAGGCCCCCTTCTCTGCC
TTCCTCACAGACAGCTTCGGCCGGCAGCACAGCTACCTGCGGATCTCCCTCCTGGAGAAGTGCAACCTCAGATGTCAGTA
CTGCATGCCGGAGGAAGGGGTCCCGCTGACCCCCAAGGCCAACCTGCTGACCACAAAAGAGATCCTGACCCTCGCCTGGC
TTTTTGTGAAGGAAGGCGTCGAAAAGATCTGGCTCATGGGCAGAGAGCCGCTCATCCAGCCGGACGAGGTGGACATTGTG
GCCCAGCTCCAGCGACTGGAAGGGCTGAGGACCATTGGTGTCACCACCAATGGCATCAGCCTGGCCCGGCTGCTGCCCCA
GCTTCAGAGGGCTGGTCTCAGCGCCATCAACATCAGCCTGGACACACTGGTGCCTGCCAAGTTTGAGTTCATTGTCCGCA
GGAAAGCCTTCCACAAGGTCATGGAGGGCATCCACAAGGCCAACGAGCCAGGCTACAACCCTGTGAAGGTGAACTGTGTG
ATGACGCGAGGCCTTAACGAGGATGAACTCCTGGACTTTGCGGCCTTGATCAAGGGCCTCCCCCTGGACGTGGCCTTCAT
AGAGTACATGCCCTTTGATGGCAACAAGTGGAACTTCAAGAAGATGGTCGCTATAAGGAGATGCTAGAAACTGTCTGGCA
GCTGTGGCCAGAGTTGGAGAAGCTGTCAGAGGAGGAATCCAGGACAGCCAAGGCCTTTAAAATCCCTGGCTTCCAAGGCC
AGATCAGCTTCATCATGTCCATGTCTGAGCATTTCTGTGGGACCTGCAACCGCCTGCAAATCACAGCTGACGGGAACCTC
AAGGTCTGCCTCTTTGGAAACTCTGAGGTATCTCTACGGGATCACTGTGATCTGGGGCCTCCAAGCAGGAGCTGCTGAGA
ATCATTGGTGCTGCCGTGGGCAGGAAGAAGCAGCAGCATGCAGGCATGTTCAGTATTTCCCAGATGAAGAACTGGCCCAT
GATCCTCATC

Alignment

ORF - retro_ggor_1234 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 87.63 %
• Parental protein coverage: 59.28 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  SRMLRRLLRSSA-RSCSSGAPVTQPCPGESARAASEELSRRRQFLREHAAPFSAFLTDSFGRQHSYLRIS
          SRMLRRLLRS.A.RSCSS..PV..P.PGES..AAS.ELSRRRQF.REH.APFSAFLTDSFGRQHSYLRIS
Retrocopy SRMLRRLLRSNA>RSCSSRVPVMPPRPGESLQAASQELSRRRQFSREHEAPFSAFLTDSFGRQHSYLRIS

Parental  LTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGVDKIRLTGGEPLIRPDVVDIVAQLQRL
          L.EKCNLRCQYCMPEEGVPLTPKANLLTT.EILTLA.LFVKEGV.KI.L.G.EPLI.PD.VDIVAQLQRL
Retrocopy LLEKCNLRCQYCMPEEGVPLTPKANLLTTKEILTLAWLFVKEGVEKIWLMGREPLIQPDEVDIVAQLQRL

Parental  EGLRTIGVTTNGINLARLLPQLQKAGLSAINISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVK
          EGLRTIGVTTNGI.LARLLPQLQ.AGLSAINISLDTLVPAKFEFIVRRK.FHKVMEGIHKA.E.GYNPVK
Retrocopy EGLRTIGVTTNGISLARLLPQLQRAGLSAINISLDTLVPAKFEFIVRRKAFHKVMEGIHKANEPGYNPVK

Parental  VNCVVMRGLNEDELLDFAALTEGLPLDVRFIEYMPFDGNKWNFKKMVS-YKEMLDTVRQQWPELEKVPEE
          VNCV..RGLNEDELLDFAAL..GLPLDV.FIEYMPFDGNKWNFKKMV..YKEML.TV.Q.WPELEK..EE
Retrocopy VNCVMTRGLNEDELLDFAALIKGLPLDVAFIEYMPFDGNKWNFKKMVA<YKEMLETVWQLWPELEKLSEE

Parental  ESSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDH-LRAGASEQELLR
          ES.TAKAFKIPGFQGQISFI.SMSEHFCGTCNRL.ITADGNLKVCLFGNSEVSLRDH.L..GAS.QELLR
Retrocopy ESRTAKAFKIPGFQGQISFIMSMSEHFCGTCNRLQITADGNLKVCLFGNSEVSLRDH<L*SGASKQELLR

Parental  IIGAAVGRKKRQHAGMFSISQMKNRPMILI
          IIGAAVGRKK.QHAGMFSISQMKN.PMILI
Retrocopy IIGAAVGRKKQQHAGMFSISQMKNWPMILI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	17.22 RPM
SRP007412_cerebellum	0.00 RPM	16.74 RPM
SRP007412_heart	0.00 RPM	11.66 RPM
SRP007412_kidney	0.00 RPM	104.80 RPM
SRP007412_liver	0.00 RPM	71.67 RPM
SRP007412_testis	0.00 RPM	12.43 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1234 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1234 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 2 parental genes, and 2 retrocopies.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000008943	1 retrocopy	retro_ggor_1234 ,
Pongo abelii	ENSPPYG00000016580	1 retrocopy	retro_pabe_1349,