RetrogeneDB ID: retro_ggor_1760

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 2b:18354106..18354665(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000005971
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: GNA11
• Ensembl ID: ENSGGOG00000014995
• Aliases: None
• Description: None

Sequence

>retro_ggor_1760
CTGGCTACGCAACAAGATGTGCTTAGAGTTCGAGTCCCCACCACAGGGATCGTCGAATACCCCTTTGACTTACAAACTGT
CATTTTCAGAATGTTCGATGTAGGGGGCCAAAGGTCAGAGAGAAGAAAATGGATACACTGCTTTGAAAATGTCACCTCTA
TCATGTTTCTAGCAGCGCTTAGTGAATATGATCAAGTTCTCGTGAGTCAGACAATGAGAACCGAATGGAGGAAAGCAAGG
CTCTCTTAGTACAATTATCACGTATCCCTGGTTCCAGAACTCCTCGGTTATTCTGTTCTTAAACAAGAAAGATCTTCCAG
AGGAGAAAATCATGTATTCCCATCTAGTCGACTACTTCCCAGAATATGATGGACCCCAGAGAGATGCCCAGGGAGCCCAA
GAATTCATTCTGAAGATGTTCGTGGACCTGAACCCAGACAGTGACAAGATTATCTACTCCCACTTCACATGCGCCACAGA
CACCGAGAATATCCGCCTTGTGTTTGCCGCCGTCAAGGACACCATCCTCCAGTTGAACCTGAAGGATTACAATCTGGTC

Alignment

ORF - retro_ggor_1760 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.95 %
• Parental protein coverage: 59.55 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  LPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV-E
          L.TQQDVLRVRVPTTGI.EYPFDL...IFRM.DVGGQRSERRKWIHCFENVTSIMFL.ALSEYDQVLV.E
Retrocopy LATQQDVLRVRVPTTGIVEYPFDLQTVIFRMFDVGGQRSERRKWIHCFENVTSIMFLAALSEYDQVLV<E

Parental  SDNENRMEESKALF-RTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAAREFIL
          SDNENRMEESKAL...TIITYPWFQNSSVILFLNKKDL.E.KI.YSHLVDYFPE.DGPQRDAQ.A.EFIL
Retrocopy SDNENRMEESKALL<STIITYPWFQNSSVILFLNKKDLPEEKIMYSHLVDYFPEYDGPQRDAQGAQEFIL

Parental  KMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
          KMFVDLNPDSDKIIYSHFTCATDTENIR.VFAAVKDTILQLNLK.YNLV
Retrocopy KMFVDLNPDSDKIIYSHFTCATDTENIRLVFAAVKDTILQLNLKDYNLV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	1.97 RPM	19.85 RPM
SRP007412_cerebellum	0.95 RPM	28.52 RPM
SRP007412_heart	0.13 RPM	8.54 RPM
SRP007412_kidney	0.70 RPM	13.21 RPM
SRP007412_liver	0.16 RPM	4.62 RPM
SRP007412_testis	4.87 RPM	24.04 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1760 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1760 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 5 parental genes, and 7 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000088256	1 retrocopy	retro_hsap_3865,
Gorilla gorilla	ENSGGOG00000013561	1 retrocopy	retro_ggor_2605,
Gorilla gorilla	ENSGGOG00000014995	3 retrocopies	retro_ggor_1760 , retro_ggor_2603, retro_ggor_2604,
Macaca mulatta	ENSMMUG00000002961	1 retrocopy	retro_mmul_1605,
Pongo abelii	ENSPPYG00000009366	1 retrocopy	retro_pabe_3045,