RetrogeneDB ID:

retro_ggor_1790

Retrocopy
location
Organism:Gorilla (Gorilla gorilla)
Coordinates:2b:75176048..75177247(-)
Located in intron of:None
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:IMPDH1
Ensembl ID:ENSGGOG00000003963
Aliases:None
Description:Inosine-5'-monophosphate dehydrogenase [Source:UniProtKB/TrEMBL;Acc:G3QMZ1]


Retrocopy-Parental alignment summary:






>retro_ggor_1790
CCCCCACGGACACTGTGACAGGCCGACATAGCCATTGCAATGGCTCTGATGGGAGGTATTGGTTTCATTCACCACAACTG
CACCCCGGAGTTCCAGGCCAAGGAGGTGCGGAAGGTCAAGAAGTTTGAACAGGGCTTCATCACGGACCCGGTGGTGCTGA
CCCCCTCGCACACTGTGGGTGATGTGTTGGAGGCCAAGATGCGGCATGGCTTCTCTGGCATCCCCATCACTGAGATGGGC
ACCATAGGCAGCAAGCTGGTGGGCATCGTCACCTCCAGAGACATCAACTTTCTTGCTGAGGAGGACCACACCACCCTCCT
CAGTGAGATGATGACACCAAGGATCGAGCTGGTGTTGGCTCCAGCAGGCCTGATGTTGAAAGAGGCAAATGAGATCCTGC
AGCATAGCAAGAAAGGGAAGCTGTCTTTCGTCAATGATTCGATGAGCTGGTGGCCATGATCACCTGCACCGACCTGAAGA
AGAACAGAGACTACCCTCTGGCCTCCAAGGATTCCCACAAGCAGCTACTGTGCAGGGCAGCTGTGGGCACCCCTGAGGAT
GACAAATACCACCTGGACTTGCTCACCCAGGCGGGGGTAGACGTCGTAGTCTTGGACTCGTCCCAAGGGAACTCGGTGTA
TCAGATTGCCACGGTGCATTACATCAAACAGAAGTACCCCCACCTCCAGGTGATTGGGAAGACAGCAGCCCAGGCCAAAA
ACCTGATTGACGCTGCGGTGGACGGGCTGCGCATAGGTATGGGCTGCGGCTCCATCTGCATCACCCAGGAAGTGATGGCC
TGCGGTAGGCGCCAGGGCACTGCATTGTACAAGGTGGCCGAGTATGCCCTGTGCTTTGGTGTGTCCATCATAGCCGATGG
CGGCATCTAGACCGTGGGGCACGTGGTTAAGGCCCTGGCCCTTGGAGCCTCCACAGTGATGATGGGCTCCCTGCTGGCCA
CCACCACGTAGGACCCCGGCAAGTATTTCTTCTCAGATAGGGTGCGGCTCAAGAAGTACCAGGGCATGGGCTCACTGGAT
GCCATGGAGAAGAGCAGCAGCAGCCAGAAATGATACGTCAGCAAGGGGAATAAGGTGAAGATCGCGCAGGGTGTCTTGGG
CTCCATCCAGGACAAAGGATCCATTCATAAGTTCGTGTCCTACCTCATAGCAGGCATCCAGCCCGGCTGCCAGGATATC

ORF - retro_ggor_1790 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 86.14 %
Parental protein coverage: 67.28 %
Number of stop codons detected: 4
Number of frameshifts detected 1


Retrocopy - Parental Gene Alignment:

ParentalPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHG
P..T...AD.AIAMALMGGIGFIHHNCTPEFQA.EVRKVKKFEQGFITDPVVL.PSHTVGDVLEAKMRHG
RetrocopyPPRTL*QADIAIAMALMGGIGFIHHNCTPEFQAKEVRKVKKFEQGFITDPVVLTPSHTVGDVLEAKMRHG
ParentalFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGK
FSGIPITE.GT.GSKLVGIVTSRDI.FLAE.DHTTLLSE.MTPRIELV.APAG..LKEANEILQ.SKKGK
RetrocopyFSGIPITEMGTIGSKLVGIVTSRDINFLAEEDHTTLLSEMMTPRIELVLAPAGLMLKEANEILQHSKKGK
ParentalLPIVNDR-DELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQ
L..VND..DELVA.I..TDLKKNRDYPLASKDS.KQLLC.AAVGT.EDDKY.LDLLTQAGVDV.VLDSSQ
RetrocopyLSFVNDS<DELVAMITCTDLKKNRDYPLASKDSHKQLLCRAAVGTPEDDKYHLDLLTQAGVDVVVLDSSQ
ParentalGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAV
GNSVYQIA.VHYIKQKYPHLQVIG....TAAQAKNLIDA.VDGLR.GMGCGSICITQEVMACGR.QGTA.
RetrocopyGNSVYQIATVHYIKQKYPHLQVIGK---TAAQAKNLIDAAVDGLRIGMGCGSICITQEVMACGRRQGTAL
ParentalYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSL
YKVAEYA..FGV.IIADGGI.TVGHVVKALALGASTVMMGSLLA.TT..PG.YFFSD.VRLKKY.GMGSL
RetrocopyYKVAEYALCFGVSIIADGGI*TVGHVVKALALGASTVMMGSLLATTT*DPGKYFFSDRVRLKKYQGMGSL
ParentalDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDI
DAMEKSSSSQK.Y.S.G.KVKIAQGV.GSIQDKGSI.KFV.YLIAGIQ.GCQDI
RetrocopyDAMEKSSSSQK*YVSKGNKVKIAQGVLGSIQDKGSIHKFVSYLIAGIQPGCQDI

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain_prefrontal_cortex 0 .00 RPM 30 .79 RPM
SRP007412_cerebellum 0 .00 RPM 31 .20 RPM
SRP007412_heart 0 .00 RPM 12 .45 RPM
SRP007412_kidney 0 .00 RPM 10 .79 RPM
SRP007412_liver 0 .00 RPM 6 .25 RPM
SRP007412_testis 0 .21 RPM 21 .76 RPM
Gorilla gorilla was not studied using ChIP-Seq data.
Gorilla gorilla was not studied using EST data.
Gorilla gorilla was not studied using FANTOM5 data.
retro_ggor_1790 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_ggor_1790 has 0 orthologous retrocopies within eutheria group .


Parental genes homology:
Parental genes homology involve 9 parental genes, and 34 retrocopies.

Species Parental gene accession Retrocopies number
Callithrix jacchus ENSCJAG000000177701 retrocopy
Homo sapiens ENSG000001063487 retrocopies
Gorilla gorilla ENSGGOG00000003963 6 retrocopies
Gorilla gorilla ENSGGOG000000132451 retrocopy
Macropus eugenii ENSMEUG000000160822 retrocopies
Macaca mulatta ENSMMUG000000145092 retrocopies
Nomascus leucogenys ENSNLEG000000123411 retrocopy
Pongo abelii ENSPPYG000000179767 retrocopies
Pan troglodytes ENSPTRG000000196607 retrocopies



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