RetrogeneDB ID: retro_ggor_2748

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 8:98339169..98339993(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: IGF2BP2
• Ensembl ID: ENSGGOG00000015035
• Aliases: None
• Description: None

Sequence

>retro_ggor_2748
AGGAACAGGAAAATTCAGATTTGAAACATACCTCCTCACCTGCAGTGGGCGATGCTGGATGCACCTTTGGCTCAACACGG
GATAGTGGAGAATGTGGAACAAGTCAACACAGACACAGAAACTGCTGTTGTCAATGTCACATATGCAACAAGGGAAGAAG
CAAAATAGCCATGGAGGAGCTAAGCGGGCATCAGTTTGAGAACTATTCCTTCAAGATTTCCTAAATCCTGGATGAAGAGG
TGAGCTCCCCTTTACCCCCTCAGCGAGCCCAGGGTGGGGACCACTCTTCCGGGAGCAAGGTCACGCCCTGGGGGCTCTTC
TCAGGCCGGACAGACTGATTTCCCGCTGCGGATCCAACCCAGTTTGTTGGTGCCATGATCTGAAAGGAGGGCTTGACCAT
AGTGAACATCACTGAGCAGACCCAGTCCCGGGTAGACATCCATAGAAAAGAGAACTCTGGAGCTGCAGAGAAGCTTGTCA
CCATCCATGCCACCCCAGAGGGGACTTCTGAAGCATGCCACACGATTCTTGAAAGCATGCAGAAAGAGGCAGATGAGACC
AAACTAGCCGAAGAGATTCCTCTGAAAATCGTGGCCCACAATGGCTTGGTTGGAAGACTGATTGGAAAAGAAGGCAGAAA
TGTGAAGAAAAATGAACATGAAACAGGGACCAAGATAACAATCTCATCCTTGCAGGATTTGAGCATATGCAACCCGGAAA
GAACCATAACTGTGAAGGGCACAGTGGGGGCCTATGCCAGTGCTGAGATGGAGATTATGAAGAAGCTGCGTGAGGCCTTT
GAAAATGATATGCTGGCTGTTAAT

Alignment

ORF - retro_ggor_2748 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.8 %
• Parental protein coverage: 53.46 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  RSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETAVVNVTYATREEAK-IAMEKLSGHQFENY
          R.RKIQI.NIPPHLQW..LD..LAQ.G.VENVEQVNTDTETAVVNVTYATREEAK.IAME.LSGHQFENY
Retrocopy RNRKIQI*NIPPHLQWAMLDAPLAQHGIVENVEQVNTDTETAVVNVTYATREEAK<IAMEELSGHQFENY

Parental  SFKISYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKN
          SFKIS.I.DEEVSSP.PPQRAQ.GDHSS......P.G....R...FP.....PTQFVGA.I.KEGLTI.N
Retrocopy SFKIS*ILDEEVSSPLPPQRAQGGDHSSGSKV-TPWGLFSGRTD*FPAAD--PTQFVGAMI*KEGLTIVN

Parental  ITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGR
          IT.QTQSRVDIHRKENSGAAEK.VTIHATPEGTSEAC..ILE.MQKEADETKLAEEIPLKI.AHNGLVGR
Retrocopy ITEQTQSRVDIHRKENSGAAEKLVTIHATPEGTSEACHTILESMQKEADETKLAEEIPLKIVAHNGLVGR

Parental  LIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN
          LIGKEGRN.KK.EHETGTKITISSLQDLSI.NPERTITVKGTV.A.ASAE.EIMKKLREAFENDMLAVN
Retrocopy LIGKEGRNVKKNEHETGTKITISSLQDLSICNPERTITVKGTVGAYASAEMEIMKKLREAFENDMLAVN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.43 RPM
SRP007412_cerebellum	0.00 RPM	6.26 RPM
SRP007412_heart	0.00 RPM	2.10 RPM
SRP007412_kidney	0.00 RPM	6.66 RPM
SRP007412_liver	0.00 RPM	0.55 RPM
SRP007412_testis	0.00 RPM	9.32 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2748 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2748 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4096

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Parental genes homology:

Parental genes homology involve 7 parental genes, and 13 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000073792	2 retrocopies	retro_hsap_216, retro_hsap_4096,
Gorilla gorilla	ENSGGOG00000008872	1 retrocopy	retro_ggor_2495,
Gorilla gorilla	ENSGGOG00000010286	1 retrocopy	retro_ggor_2520,
Gorilla gorilla	ENSGGOG00000015035	2 retrocopies	retro_ggor_2679, retro_ggor_2748 ,
Myotis lucifugus	ENSMLUG00000002631	1 retrocopy	retro_mluc_599,
Macaca mulatta	ENSMMUG00000023416	3 retrocopies	retro_mmul_2361, retro_mmul_409, retro_mmul_530,
Pongo abelii	ENSPPYG00000014373	3 retrocopies	retro_pabe_1723, retro_pabe_281, retro_pabe_837,