RetrogeneDB ID: retro_ggor_2967

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: X:137085782..137086322(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SRD5A1
• Ensembl ID: ENSGGOG00000016593
• Aliases: None
• Description: None

Sequence

>retro_ggor_2967
CGCAGCGCGCCCAGCTGCATCCTCCTGGCCATGTTTCTCGTCCACTACTGGCATCGGTGCTTAATTTACCCATTTCTGAT
GCGAGGAGGAAAGCCTGTGCCACTGTTGGCATGCACAATGGCGATTATGTTCTGTACCTGTAATGGCTATTTGCAAAGCA
GATACTTGAGCCATTGTGCAGCGTATGCTGATGACTGAGTAAAAGATCCCCGTTTTCTAATAAATTTTGGCTTGTGGTTA
ACGGGCATGTTGATAAACATCCATTCAGATCATATCCTAAGGAATCTCAGAAAAACAGGAGATACTGGATACAAAATACC
AAGGGGAGGCTTATTTGAATACATAACTGCAGGCAACTATTTTGGAGAAATCATGGAGTGGCGTGGCTATGCCCTGGCCA
GCTGGTCTGTCCAAGGCGCGACTTTTGCTTTCTTCACATTTTGTTTTTTATCTGGTAGAGCAAAAGAGCATCATGAGCGG
TACCTCCGGAAATTTGAAGAGTATCCAAAGTTCAGAAAAATTATAATTCCATTTTTGTTT

Alignment

ORF - retro_ggor_2967 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 92.78 %
• Parental protein coverage: 69.5 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  RSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDP
          RSAP.CILLAMFLVHY.HRCLIYPFLMRGGKP.PLLACTMAIMFCTCNGYLQSRYLSHCA.YADD.V.DP
Retrocopy RSAPSCILLAMFLVHYWHRCLIYPFLMRGGKPVPLLACTMAIMFCTCNGYLQSRYLSHCAAYADD*VKDP

Parental  RFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGA
          RFLI.FGLWLTGMLINIHSDHILRNLRK.GDTGYKIPRGGLFEY.TA.NYFGEIMEW.GYALASWSVQGA
Retrocopy RFLINFGLWLTGMLINIHSDHILRNLRKTGDTGYKIPRGGLFEYITAGNYFGEIMEWRGYALASWSVQGA

Parental  AFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF
          .FAFFTFCFLSGRAKEHHE.YLRKFEEYPKFRKIIIPFLF
Retrocopy TFAFFTFCFLSGRAKEHHERYLRKFEEYPKFRKIIIPFLF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	15.20 RPM
SRP007412_cerebellum	0.00 RPM	6.58 RPM
SRP007412_heart	0.00 RPM	0.47 RPM
SRP007412_kidney	0.00 RPM	3.80 RPM
SRP007412_liver	0.00 RPM	26.43 RPM
SRP007412_testis	0.00 RPM	1.97 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2967 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2967 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4763
Pongo abelii	retro_pabe_3708

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Parental genes homology:

Parental genes homology involve 6 parental genes, and 6 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000005509	1 retrocopy	retro_chof_873,
Homo sapiens	ENSG00000145545	1 retrocopy	retro_hsap_4763,
Gorilla gorilla	ENSGGOG00000016593	1 retrocopy	retro_ggor_2967 ,
Nomascus leucogenys	ENSNLEG00000011414	1 retrocopy	retro_nleu_2347,
Pongo abelii	ENSPPYG00000015333	1 retrocopy	retro_pabe_3708,
Tursiops truncatus	ENSTTRG00000012679	1 retrocopy	retro_ttru_1340,