RetrogeneDB ID: retro_ggor_776

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 12:11548462..11549602(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: DDX55
• Ensembl ID: ENSGGOG00000026102
• Aliases: None
• Description: None

Sequence

>retro_ggor_776
TCTCCTCTGTTCCAAGTTTAAGAGTTTAAGCAACAAGGTGGGAACATCACTGTGGCCATTCCAGGCCACTTGAAGACATG
TTCTGAAGGAAGGCAAAAGGCTTGTATCTGGCCAGCTGTGTGTGATCCCTGCATATCCTGGTGTTGGATGAGGCAGACAG
ACTTCTGGACATGGGATTTGAGGCAAGCATAAATACCATCCTGGAGTTTTTGCCAAAGCAGAGGAGAACAGGCCTTTTCT
CTGCCACTCAGAAGCAGGAAGTGGAGAACTTGGGGAGAGTGGGACTCCGGAACCCTGTCCAGTCTCAGTGAAGAAGGGTG
TGGCAGCCAGCAGTGCCCAGAACACCACTCTCCCCTGGAAAACTACTACACTGGTATGCAAGGCAGATGAGAAATTTAAT
CAGCTGCTACATTTTCTTCGCAGTCATAAGCAAGAGCAACACCTGGTCTTCTTTAGCACCTGCACCTGTGTGGAATACTA
CAGGAAGGCTCTGGAGGTGCTGATGAAGAGTGTGAAGATTGTGTGCATCCATGGAAAGATGAAATACGATCTTCATGCAA
ATTGAAAATTGCAATTGTTCTGCAAATTGCAAAGTGGAATTTTAGTGTGCACTGATGTGGTGGCCCAGGAATCAATATTC
CTGAAGTAAACTGGGTTTTGCAGTACAATCACCCCTACAATGCAAGTGCCTTTGTGCAGCACTGTGGCCGCACAGCCCTC
ATTAGCCACAGAGGCAGAGCTCTGGTGTTCCTCCCGCCCGTGGAAGAGTCATACATCAATTTCCTTGCAATTAACCAAAA
ATGCCCCCTGGCGGAGATGAAACTCTAGAAAAACACAGCTGACCTTCTGCCAAAACTCAAGTCCATGACCCTGGCAGAAA
CATCTGTGTTTGAAAAGGGCATGAAAGCTTTTGTGTCCTATGTCCAGGCTTATGCAAAGTAAGAATGCAACCTGATTTTC
AGATTAAATAATCTTGATTTTGCAAGTCTTGCTTGAGGTTTTTCCCTGCTGAGAATGCCCAAGATGCCAGAATTGAGAGG
AAAGCAGTTTCCAGATTTTGTGCCTGTGGACATTAATACAGACACTATTTCATTTAAAGATAAAATTAGAGAAAAGCGGA
GGCAGAAATTACTGGAGCAA

Alignment

ORF - retro_ggor_776 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.33 %
• Parental protein coverage: 63.33 %
• Number of stop codons detected: 7
• Number of frameshifts detected: 5

Retrocopy - Parental Gene Alignment:

Parental  NPGEDVGRFKQQGGNIIVATPGRL-EDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILE
          .P...V..FKQQGGNI.VA.PG.L.EDMF.RKA.GL.LASCV.SL..LVLDEADRLLDMGFEASINTILE
Retrocopy SPLFQV*EFKQQGGNITVAIPGHL<EDMF*RKAKGLYLASCV*SLHILVLDEADRLLDMGFEASINTILE

Parental  FLPKQRRTGLFSATQTQEVENLVRAGLRNPVR-VSVKEKGVAASSAQKTP-SRLENYY-MVCKADEKFNQ
          FLPKQRRTGLFSATQ.QEVENL.R.GLRNPV..VSVK.KGVAASSAQ.T..S.LENYY..VCKADEKFNQ
Retrocopy FLPKQRRTGLFSATQKQEVENLGRVGLRNPVQ<VSVK-KGVAASSAQNTT<SPLENYY>LVCKADEKFNQ

Parental  LVHFLRNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMCIHG--KMKYKRNKIFMEFRKLQSGILVCT
          L.HFLR.HKQE.HLVFFSTC.CVEYY.KALEVL.K.VKI.CIHG..K.....N.....F.KLQSGILVCT
Retrocopy LLHFLRSHKQEQHLVFFSTCTCVEYYRKALEVLMKSVKIVCIHGKMKYDLHAN*KLQLFCKLQSGILVCT

Parental  DVMAR-GIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEESYINFLAINQKCPLQEM
          DV.A..GI.IPEVNWVLQY..P.NASAFV..CGRTA.I.H.G.ALVFL.P.EESYINFLAINQKCPL.EM
Retrocopy DVVAQ<GINIPEVNWVLQYNHPYNASAFVQHCGRTALISHRGRALVFLPPVEESYINFLAINQKCPLAEM

Parental  KLQRNTVDLLPKLKSMALADRAVFEKGMKAFVSYVQAYAKHECNLIFRLKDLDFASLARGFALLRMPKMP
          KL..NT.DLLPKLKSM.LA...VFEKGMKAFVSYVQAYAK.ECNLIFRL..LDFASLA.GF.LLRMPKMP
Retrocopy KL*KNTADLLPKLKSMTLAETSVFEKGMKAFVSYVQAYAK*ECNLIFRLNNLDFASLA*GFSLLRMPKMP

Parental  ELRGKQFPDFVPVDVNTDTIPFKDKIREKQRQKLLEQ
          ELRGKQFPDFVPVD.NTDTI.FKDKIREK.RQKLLEQ
Retrocopy ELRGKQFPDFVPVDINTDTISFKDKIREKRRQKLLEQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.29 RPM	18.51 RPM
SRP007412_cerebellum	0.00 RPM	30.45 RPM
SRP007412_heart	0.03 RPM	4.57 RPM
SRP007412_kidney	0.04 RPM	21.34 RPM
SRP007412_liver	0.03 RPM	14.98 RPM
SRP007412_testis	0.21 RPM	18.65 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_776 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_776 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 3 parental genes, and 3 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000111364	1 retrocopy	retro_hsap_964,
Gorilla gorilla	ENSGGOG00000026102	1 retrocopy	retro_ggor_776 ,
Pan troglodytes	ENSPTRG00000005601	1 retrocopy	retro_ptro_668,