RetrogeneDB ID: retro_rnor_1086

Retrocopy location

• Organism: Rat (Rattus norvegicus)
• Coordinates: 15:10056349..10056738(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Egln1
• Ensembl ID: ENSRNOG00000019773
• Aliases: None
• Description: Egl nine homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:P59722]

Sequence

>retro_rnor_1086
GGGCAGCACCAGGCCATGGTTGCTTGTTACCCAGGCAACAGAACAGGCTACATCCGTCATGTCAAAACCCAAACGGAGGA
GGAAGATGTGTGATCTGTTTATATTATCTAAATAAAAACTGGGACGCCAAACTAAGTGGAGGTATTCTTCAAATTTTTCC
AGGAGGCAAAGCCCAGTTTGCTGGCATTGAACCCATATTCGATAGATTGCGCTTTTTCTGGTCTGACAGGCATAACCCTC
ATCAAGTAGAGCAAGGATGCACTACAAGCTGTGCAATAATTGTTTGGTATTTTGATCTAGAAGAGAAAGCAAAAGCTAAG
GTAAAATATCTAACAAGTGAGAAAGGTGTGAGCATTGAACTCAAGCCCCAGTCAGTCAGCAAAGTTGTC

Alignment

ORF - retro_rnor_1086 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 72.52 %
• Parental protein coverage: 58.56 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  GRTKAMVACYPGNGTGYVRHV-DNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDR
          G...AMVACYPGN.TGY.RHV..NPNG.GRCV.C.YYLNK.WDAK.SGGIL.IFP.GKAQFA.IEP.FDR
Retrocopy GQHQAMVACYPGNRTGYIRHV<QNPNGGGRCVICLYYLNKNWDAKLSGGILQIFPGGKAQFAGIEPIFDR

Parental  LLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELKPNSVSKDV
          L.FFWSDR.NPH.V.....T..AI.VWYFD..E.A.AKVKYLT.EKGV..ELKP.SVSK.V
Retrocopy LRFFWSDRHNPHQVEQGCTTSCAIIVWYFDLEEKAKAKVKYLTSEKGVSIELKPQSVSKVV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	19.20 RPM
SRP017611_kidney	0.00 RPM	28.05 RPM
SRP017611_liver	0.00 RPM	6.72 RPM

ChIP-Seq

Rattus norvegicus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_rnor_1086 retrocopy.

TSS

Rattus norvegicus was not studied using FANTOM5 data.

Lab

retro_rnor_1086 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_rnor_1086 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 3 parental genes, and 13 retrocopies.

Species	Parental gene accession	Retrocopies number
Echinops telfairi	ENSETEG00000007202	1 retrocopy	retro_etel_1722,
Rattus norvegicus	ENSRNOG00000019773	11 retrocopies	retro_rnor_1086 , retro_rnor_1783, retro_rnor_2109, retro_rnor_2110, retro_rnor_2411, retro_rnor_2885, retro_rnor_2938, retro_rnor_2939, retro_rnor_2955, retro_rnor_507, retro_rnor_948,
Ictidomys tridecemlineatus	ENSSTOG00000023570	1 retrocopy	retro_itri_1697,