Query: CNT0015141
Subject: sp|Q8GY23|UPL1_ARATH E3 ubiquitin-protein ligase UPL1 OS=Arabidopsis

thaliana GN=UPL2 PE=1 SV=3

 Score = 1115 bits (2884), Expect = 0.0,   Method: Compositional matrix adjust.
Identities = 726/2062 (35%), Positives = 1120/2062 (54%), Gaps = 163/2062 (7%)

Query: 30 SEPPPKIKAFTDKVIQCPLQDIAIPLSGFRWEYGKGNFHHWRPLFLHFDTYFKTYLCSRK 89
SE P KI F + V PL+ I PL+ FRWE+ KG+FHHW LF HFDT+F+ ++ RK
Sbjct: 9 SEVPTKISLFINSVTSVPLELIQEPLASFRWEFDKGDFHHWVDLFYHFDTFFEKHVKVRK 68

Query: 90 DLGLSDNILGDDSPFPKQAVLQILRVMQIILENCHNKGSFSGLE-HFMLLLASTDPEILI 148
DL + + D PFPK AVLQ+LRV++++LENC NK ++ E H LLLASTD +++
Sbjct: 69 DLRIEEEFDESDPPFPKDAVLQVLRVIRLVLENCTNKQFYTSYEQHLSLLLASTDADVVE 128

Query: 149 ATLETLAVLVKINPSKLHASGKL-VGCGTINSCLLSLAQGWGSKEEGLGLYYCVTVNERS 207
A L+TLA +K +GK + ++N L SLAQGWG KEEGLGL C T
Sbjct: 129 ACLQTLAAFLK------RPTGKYSIRDASLNLKLFSLAQGWGGKEEGLGLTSCAT----- 177

Query: 208 QDEGLSLFPSNVENDGDKSLYHLGSTLYFELHSANAQSNAEAEDGAVSTSMSVINIPDLH 267
E+ D+ LG TL FE ++++ +S +E G + VI++PD+
Sbjct: 178 ------------EHSCDQLFLQLGCTLLFEFYASD-ESPSELPGG-----LQVIHVPDVS 219

Query: 268 VRKEEDLSLMKFCIEQYNVPPEQRFALLTRIRYAHAFRSPRVCRLYSKICLLAFIVLVQA 327
+R E DL L+ + +NVPP RFALLTR+R+A AF S + Y+ I L AFIVLVQA
Sbjct: 220 MRSESDLELLNKLVIDHNVPPSLRFALLTRLRFARAFSSLATRQQYTCIRLYAFIVLVQA 279

Query: 328 SDSHDELASFFANEPEYTNELIRIVRSEETISGNVRTLAMNALGAQLAAYASSHERARIL 387
S + + SFF EPE+ NEL+ +V E+T+ +R L + +L A S +R R
Sbjct: 280 SGDTENVVSFFNGEPEFVNELVTLVSYEDTVPAKIRILCLQSL------VALSQDRTRQP 333

Query: 388 SGSSISFAGGNRMILLNVLQRAIXXXXXXXXXXXXXFVEAVLQFYLLHXXXXXXXXXXXX 447
+ + +GG+R +L ++Q+AI F EA+L +
Sbjct: 334 TVLTAVTSGGHRGLLSGLMQKAIDSVICNTSKWSLAFAEALLSLVTV-LVSSSSGCSAMR 392

Query: 448 XXXMVPTFLPLVEDADPAHIHLVCLAVKTLQKLLDYSNAAVTLFKDLGGVELLANRLQIE 507
++PT +PL++D DP H+HLV AV L+ +DYSN A LF+DLGG++ RL+ E
Sbjct: 393 EAGLIPTLVPLIKDTDPQHLHLVSTAVHILEVFMDYSNPAAALFRDLGGLDDTIFRLKQE 452

Query: 508 VHRVIDVA----------GDDDNSMVIGEHFKSSEEQI-YSQKRLIRVLLKALGSATYAP 556
V R D G +D++ E SE I Y ++ L++ LL+A+ TYAP
Sbjct: 453 VSRTEDDVKEIVCCSGSNGPEDDT----EQLPYSEALISYHRRLLLKALLRAISLGTYAP 508

Query: 557 ANSARSQGSNDASLPATLCLLFSNVEKFGGDIYSSAVTVMSEIIHKDPTCFPALHELGLP 616
N+ GS ++ LP LC++F + FGG ++S A TVMS++IHKDPTCF AL GL
Sbjct: 509 GNT-NLYGSEESLLPECLCIIFRRAKDFGGGVFSLAATVMSDLIHKDPTCFNALDSAGLT 567

Query: 617 IAFLSSVVSGILPSPKALTCVPNGLGAICLNPKGLESVKETSALRFLVDIFTNKKYVVAM 676
AFL ++ ++ S +A+TC+P L A+CLN GL++VK+ +ALR V IF++ Y+ A+
Sbjct: 568 SAFLDAISDEVICSAEAITCIPQCLDALCLNNSGLQAVKDRNALRCFVKIFSSPSYLKAL 627

Query: 677 NEGIV-PLANAVEELLRHVSSLRGTGVDLIIEIVNSIASRGDGEHAESSGKSSXXXXXXX 735
L++ ++ELLRH SSLR GVD+ IEI+NSI G G A +S KS+
Sbjct: 628 TSDTPGSLSSGLDELLRHQSSLRTYGVDMFIEILNSILIIGSGMEATTS-KSADVPTDAA 686

Query: 736 XXXNRESVASSSLV---ESTYSSGETISD-EQFIQLAVFHVMVLVHRTMENSETCRLFVE 791
V SL E+ SS + ++ E F+ V +V L ++N+E C LFVE
Sbjct: 687 PVPMEIDVDEKSLAVSDEAEPSSDTSPANIELFLPDCVCNVARLFETVLQNAEVCSLFVE 746

Query: 792 KSGIESLLKLLLRPSVAQSSEGMSIALHSTMVFKTFTQHHSAALARAFCSFLKDHLKKAL 851
K GI+++L+L P + S+ S+ ++ FK F+ HSA LAR CS+L++HLKK
Sbjct: 747 KKGIDTVLQLFSLPLMPLST---SLGQSFSVAFKNFSPQHSAGLARILCSYLREHLKKTN 803

Query: 852 SGFDVVSGAFMLDPKSTPDRTXXXXXXXXXXXXXAASKDNRWVTALLTEFGNGSKDVLED 911
+ + G +L +S ++ + ++++E + DVL++
Sbjct: 804 NLLVSIEGTQLLKLESAVQTKILRSLSCLEGMLSLSNFLLKGSASVISELSAANADVLKE 863

Query: 912 IGRIHREILWQLALLEESKVDVEEGSAGATDEARQSELSTT--DSEEQRLNSFR-QFLDP 968
+G +++ +WQ+AL ++K D ++ A+D + + ST +S+E N+ ++ +P
Sbjct: 864 LGITYKQTIWQMALCNDTKEDEKKSVDRASDNSVSASSSTAERESDEDSSNALAVRYTNP 923

Query: 969 L---LRRRMSGWSFESQFFDLINLYRDL---TRASSIQQRQTTDGPSNVRIEASHQSQQA 1022
+ S W +F ++ R + TR + + R G + +E+ + +
Sbjct: 924 VSIRSSSSQSIWGGHREFLSVVRSGRGVHGHTRHAIARMR---GGRTRRHLESFNFDSEI 980

Query: 1023 GSLDDAGTSNRKEDKQRSYYHSCRDMVKSLSIHITHLFQEMGKVMLLPSRRRDDTLNVSA 1082
+ D TS+ E K++S +++ L+ + F + K +RRR D ++S+
Sbjct: 981 PA-DLPVTSSSHELKKKSTEVLIAEILNKLNCTLRFFFTSLVKGFTSANRRRIDGPSLSS 1039

Query: 1083 PSKSVASTFASIAIDHMNFGGH-VTSGSEASVSTKCRYFGKVIEFIDGILLD-KPDSCNA 1140
SK++ + A + ++ +NF G+ +G + S+S KCRY GKV++ I + D + C
Sbjct: 1040 ASKTLGTALAKVFLEALNFQGYGAAAGPDTSLSLKCRYLGKVVDDITFLTFDTRRRVCFT 1099

Query: 1141 VILNCLYGRGVIQSVLTTFEATSQLLFAVNRAPTSPMETDETHTRQDGVED--ADRSWIY 1198
++N Y G + +LTTFEATSQLL+ V P S + T + G + + W+
Sbjct: 1100 AMVNSFYVHGTFKELLTTFEATSQLLWKV---PFS-IRASSTENEKSGERNLWSHSKWLV 1155

Query: 1199 GPLGSYGKLMDHLATSSLILSPFTK-HLLTQP----LVSGDIPFPQDEETFVKVLQSMVL 1253
L +Y + +D+ S+ +LSP ++ LL QP L G P P++ ETFV+ LQS VL
Sbjct: 1156 DTLQNYCRALDYFVNSTYLLSPTSQTQLLVQPASVDLSIGLFPVPREPETFVRNLQSQVL 1215

Query: 1254 KTVLPVWTHPQFTDCNYDFIAAILNIIRHIYSGVEVKNTNSTAA------RVSGPPPNET 1307
+ +LP+W HP F DCN +F+A++ +++ HIYSGV N + A R P+E
Sbjct: 1216 EVILPIWNHPMFPDCNPNFVASVTSLVTHIYSGVVDTRENRSGATQGTNQRALPLQPDEA 1275

Query: 1308 TISTIVEMGFSRNRAEEALRQVGSNSVELAMEWLFSHPEE-VQEDDELARALAMSLGNSG 1366
+ IVEMGFSR+RAE+ALR+VG+NSVE+AM+WLF++PE+ VQEDDELA+ALA+SLGNS
Sbjct: 1276 IVGMIVEMGFSRSRAEDALRRVGTNSVEMAMDWLFTNPEDPVQEDDELAQALALSLGNSS 1335

Query: 1367 SEAK-EDVPKESSVTIEEEMVQPPPVDELLSTCRKLLQMKDSLAFPVRDLLVMICSQNDG 1425
K ED K V EE + PPVDE+++ KL Q DS+AFP+ DL V +C++N G
Sbjct: 1336 ETPKLEDTEKPVDVPQEEAEPKEPPVDEVIAASVKLFQSDDSIAFPLVDLFVTLCNRNKG 1395

Query: 1426 EHRSAVVSFIVEQVKLSS-NVSEDGNRSILSNLFHVLALILNEDTDAREIAAKNGLVNVS 1484
E R +V ++++Q+KL + S+D L+ + H+LAL+L+ED + REIAA++G+V V+
Sbjct: 1396 EDRPKIVFYLIQQLKLVQLDFSKD--TGALTMIPHILALVLSEDDNTREIAAQDGIVAVA 1453

Query: 1485 SDLLSQWISSTFDREKV--PKWVTAAFVAIDRLAQVDQKVNADILEQLKG-----DDATQ 1537
+L+ + + + PK ++A + + + Q +++++ +E +G D+ Q
Sbjct: 1454 IGILTDFNLKSESETDILAPKCISALLLVLSMMLQAQTRLSSEYVEGNQGGSLVLSDSPQ 1513

Query: 1538 KSVSINED---------KYNKLQSSL---STKYLDVQEQKQLVEIACGCMRNQLPSETMH 1585
S + +D + N+ S+ ST YL ++E +++ IACG ++ ++P+ M
Sbjct: 1514 DSTAALKDALSSDVAKGESNQALESMFGKSTGYLTMEESSKVLLIACGLIKQRVPAMIMQ 1573

Query: 1586 AVLQLCATLTRTHSVAVNXXXXXXXXXXXXXXXXXXFIGFDNIAATIIRHVLEDPQTLQQ 1645
AVLQLCA LT++H++A+ F G+D +A+ I+RH++EDPQTLQ
Sbjct: 1574 AVLQLCARLTKSHALAIQFLENGGLSSLFNLPKKCFFPGYDTVASVIVRHLVEDPQTLQI 1633

Query: 1646 AMEAEIRHNVVSASNRQSSGRLTPRNFLLNLTSVIQRDPVIFMRAAHSVCQVEMVGERPY 1705
AME EIR + S ++ GR+ PR FL + VI RDPV+FM+A S CQ+E G +
Sbjct: 1634 AMETEIRQTL---SGKRHIGRVLPRTFLTTMAPVISRDPVVFMKAVASTCQLESSGGTDF 1690

Query: 1706 VVLLXXXXXXXXXXXXXXXXXXXXXXMQNADLXXXXXXXXXXXXXXXLDASSKNVKVHRK 1765
V+L + L D S K K HR+
Sbjct: 1691 VILTKEKEKPKVSGSEHGFSLNEPLGISENKLH---------------DGSGKCSKSHRR 1735

Query: 1766 PPHSFVSVIELLLDPVVKFVPSLKDEPATKENLGSTDMEIDXXXXXXXXXXXXXXXXXXX 1825
P +F+ VI+ L+D V+ F P LK + NL S M++D
Sbjct: 1736 VPTNFIQVIDQLIDIVLSF-PGLKRQEGEAANLIS--MDVDEPTTKVKGKSKVGEPEKAE 1792

Query: 1826 XDNHELSAYMAKIVFILKLLTEILLMYTASVHILIRKDSEVSSCIAVPLRTGHLA----- 1880
+ E S +A++ FILKLL++I+LMY +++R+D+E+S LR +L
Sbjct: 1793 LGS-EKSEELARVTFILKLLSDIVLMYLHGTSVILRRDTEISQ-----LRGSNLPDDSPG 1846

Query: 1881 -GGIFHHILHKFLPYTKSSKKERKTDVDWRQKLSSRASQFLVASCVRSTEARKRIFTEIN 1939
GG+ +H++H+ LP S ++ +W++KLS +AS FLV C RS E RKRI E+
Sbjct: 1847 NGGLIYHVIHRLLPI---SLEKFVGPEEWKEKLSEKASWFLVVLCSRSNEGRKRIINELT 1903

Query: 1940 SVFSDFVEFG----SGFRAPGIEIQAFIDLLSDVLTARAPT----GSSISAEASATFIDV 1991
V S F G P + AF +L+ +LT + + G S + + + ID
Sbjct: 1904 RVLSVFASLGRSSSQSVLLPDKRVLAFANLVYSILTKNSSSSNFPGCGCSPDVAKSMIDG 1963

Query: 1992 GLVQSLTRALHVLDLDHTDSSK 2013
G +Q LT L+V+DLDH D+ K
Sbjct: 1964 GTIQCLTSILNVIDLDHPDAPK 1985



Score = 1105 bits (2858), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 671/1383 (48%), Positives = 831/1383 (60%), Gaps = 114/1383 (8%)

Query: 2315 DAYSDRSSEGTSS--RLDSVFRSLRSSRHGQRFNFWTNDNQQSGGSGASALPQGFEDLLV 2372
D +SDR G + D + SSR G + WT+ S ++++ Q E+ +
Sbjct: 2344 DPFSDRLGGGGAPPPLTDYSVVGMDSSRRGVGDSRWTDVGHPQPSSLSASIAQLIEEHFI 2403

Query: 2373 SHLRRPSPEKSADQDATEGS----QNRGEATQFVGS----------GEMAAESAMENNN- 2417
++LR +P + + T + Q + + VGS GE + E + NNN
Sbjct: 2404 TNLRASAPVDTVVERETNTTEVQEQQQPDVPPSVGSETVLGDGNEGGEQSEEHELLNNNE 2463

Query: 2418 -INEARDASTPSTV----LDESGGANVTPVANVSSQGTDAPSSQSQPVEMQFEQNDVAIR 2472
++ STP+ + + E GGA P+ V
Sbjct: 2464 VMHPLPLNSTPNEIDRMEVGEGGGA---PIEQV--------------------------- 2493

Query: 2473 DVEAVSQESSGSGATLGESLRSLDVEIGSADGHDDGGDRQGSADARIRRTNVSFGNSTQV 2532
D EAV SS G + ++++ V D + Q S D + S Q
Sbjct: 2494 DREAVHLISSAQGQSDTSGIQNVSVTAIPPPVDDPDSNFQPSVDVDMSSDGAEGNQSVQP 2553

Query: 2533 SARDVALHSVSEASEHPNQEAEQSGPNDEQQRNVDADS-----GSIDPAFLEALPEELRA 2587
S D + +E + EA Q NDEQ D +IDP FLEALPE+LRA
Sbjct: 2554 SPLD------GDNNELSSMEATQDVRNDEQVDEGSLDGRAPEVNAIDPTFLEALPEDLRA 2607

Query: 2588 EVLSAQQGQATQPPNSEPQNGGDIDPEFLAALPSDIREEVXXXXXXXXXXXSQELEGQPV 2647
EVL++QQ Q+ QPP EP + DIDPEFLAALP +I+ EV Q+ +GQPV
Sbjct: 2608 EVLASQQAQSVQPPTYEPPSVDDIDPEFLAALPPEIQREVLAQQRAQRML--QQSQGQPV 2665

Query: 2648 EMDTVSIIATFPSELREEVLLTSSDAILANLTPALVAEANMLRERFARRYN--RTLFGMY 2705
+MD SIIAT P++LREEVLLTSS+A+LA L P L+AEA MLR+R R Y +FG
Sbjct: 2666 DMDNASIIATLPADLREEVLLTSSEAVLAALPPPLLAEAQMLRDRAMRHYQARSRVFGSS 2725

Query: 2706 PR---SRRGDSRRNEQLDRAGG-TLSRRSA-----GSKPLEADGSPLVDTEGLRALVRLL 2756
R R G R ++R G T+ +R G K E +G PLV+ + L++L+RLL
Sbjct: 2726 HRLNNRRNGLGYRLTGMERGVGVTIGQRDVSSSADGLKVKEIEGDPLVNADALKSLIRLL 2785

Query: 2757 RVFQPIYKVPLQRLMLNLSAHAETRTALVKIFMDLLMLDVGQPANDLNTAEPPYRLYGCQ 2816
R+ QP+ K LQRL+LNL AH+ TR LV++ +D++ ++ ++L P RLYGCQ
Sbjct: 2786 RLAQPLGKGLLQRLLLNLCAHSFTRANLVQLLLDMIRPEMETLPSELALTNP-QRLYGCQ 2844

Query: 2817 SNVMYSRPQHLDGIPPLLSRRVLETLTYLAKNHSLVAKTLLEFRLPRPVLEGPIVPDQRR 2876
NV+Y R Q L+G+PPL+ RRVLE LTYLA NHS VA L F R+
Sbjct: 2845 LNVVYGRSQLLNGLPPLVFRRVLEVLTYLATNHSAVADMLFYFDSSLLSQL-----SSRK 2899

Query: 2877 GK-AVMVEADGPDRWQXXXXXXXXXXXXXXXXXXXXXSVAHXXXXXXXXXXXXXXTESKS 2935
GK V E D D S +H S+
Sbjct: 2900 GKEKVTHETDSRD-----LEIPLVVFLKLLNRPQLLQSTSHLALVMGLLQVVVYTAASRI 2954

Query: 2936 NAREEPGTSSTEQLTGPPIQSAAEMNTESHAASSEVEDKSGASSSVASRDQSTXXXXXXX 2995
P + E+L P+ ASSE + + + SVA R
Sbjct: 2955 EGWS-PSSGVPEKLENKPV---------GEEASSETQKDAESELSVARRKNCAELYNIFL 3004

Query: 2996 X--XXXXXXXCSLLAREGLSDNAYSLVAEVLKKLVAIAPAICHLFITELAGSVQSLTRSA 3053
C LL EGLSD YSL EVLKKL A+ F EL+ L+ S
Sbjct: 3005 QLPQSDLCNLCMLLGYEGLSDKIYSLAGEVLKKLAAVDVTHRKFFTKELSELASGLSSST 3064

Query: 3054 MDELNKFREVEKALLSTTSTDGAVILRVLQALSSLVASIGDKNNENQIISEKEHGATISL 3113
+ L +K +T S GA ILRVLQ LSSL ++I D N +++E ++
Sbjct: 3065 VRVLATLSTTQKMSQNTCSMAGASILRVLQVLSSLTSTIDDSNVGTDKETDQEEQ---NI 3121

Query: 3114 VWDINTALEPLWQELSTCISTIE---SFSETAPNLPRSSIVTSSKPAGAMPPLPAGTQNI 3170
+ + ALEPLWQEL CIS E + N+ V P ++ P GTQ++
Sbjct: 3122 MQGLKVALEPLWQELGQCISMTELQLDHTAATSNVNPGDHVLGISPTSSLSP---GTQSL 3178

Query: 3171 LPYIESFFVMCEKLH-PGHLGAGQEFSIATVPDPEEATASAMQPKTPTSATKVDEKHIAF 3229
LP IE+FFV+CEK+ P L Q+ + T + +E++ KT + K + + F
Sbjct: 3179 LPLIEAFFVLCEKIQTPSML---QQDATVTAGEVKESSTHGSSSKTIVDSQKKIDGSVTF 3235

Query: 3230 VKFAEKHKKLLNAFVRQNPGLLEKSFSIMLKVPRFVDFDNKRSYFRSKIKHQHDHHHS-P 3288
KF EKH++LLN+FVRQNP LLEKSFS+MLK PR +DFDNK++YFRS+I+HQHD H S P
Sbjct: 3236 SKFVEKHRRLLNSFVRQNPSLLEKSFSMMLKAPRLIDFDNKKAYFRSRIRHQHDQHISGP 3295

Query: 3289 LRISVRRAYILEDSYNQLRMRTTQELKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDK 3348
LRISVRRAY+LEDSYNQLRMR+ Q+LKGRL V FQGEEGIDAGGLTREWYQLLSRVIFDK
Sbjct: 3296 LRISVRRAYVLEDSYNQLRMRSPQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDK 3355

Query: 3349 GALLFTTVGNEATFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHIL 3408
GALLFTTVGN+ATFQPNPNSVYQTEHLSYFKFVGR+V KALFDGQLLDV+FTRSFYKHIL
Sbjct: 3356 GALLFTTVGNDATFQPNPNSVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHIL 3415

Query: 3409 GAKVTYHDIEAIDPDYFKNLKWLLENDISDILDLTFSIDADEEKLILYERNEVTDYELIP 3468
G KVTYHDIEA+DPDY+KNLKWLLEND+SDILDLTFS+DADEEK ILYE+ EVTDYEL P
Sbjct: 3416 GVKVTYHDIEAVDPDYYKNLKWLLENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKP 3475

Query: 3469 GGRNIRVTEENKQQYVDLVAEHRLTTAIRPQINAFLEGFSELIPRELISIFHDKELELLI 3528
GGRNIRVTEE K +YVDLVA+H LT+AIRPQINAFLEG +ELIPREL+SIF+DKELELLI
Sbjct: 3476 GGRNIRVTEETKHEYVDLVADHILTSAIRPQINAFLEGLNELIPRELVSIFNDKELELLI 3535

Query: 3529 SGLPDIDLDDLRANTEYSGYSPASPVIQWFWEVVQAFSKEDKARLLQFVTGTSKVPLEGF 3588
SGLP+ID DDL+ANTEY+ Y+ SPVI+WFWEVV+AFSKED AR LQFVTGTSKVPLEGF
Sbjct: 3536 SGLPEIDFDDLKANTEYTSYTVGSPVIRWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGF 3595

Query: 3589 SALQGISGSQKFQIHKAYGSADHLPSAHTCFNQLDLPEYPSKEHLEERLLLAIHEANEGF 3648
ALQGISG Q+ QIHKAYGS + LPSAHTCFNQLDLPEY SKE ++ERLLLAIHEANEGF
Sbjct: 3596 KALQGISGPQRLQIHKAYGSPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIHEANEGF 3655

Query: 3649 GFG 3651
GF
Sbjct: 3656 GFA 3658

Query: CNT0015141
Subject: sp|Q9P4Z1|TOM1_NEUCR E3 ubiquitin-protein ligase TOM1-like

thaliana GN=UPL1 PE=1 SV=3

 Score = 1109 bits (2868), Expect = 0.0,   Method: Compositional matrix adjust.
Identities = 723/2067 (34%), Positives = 1114/2067 (53%), Gaps = 163/2067 (7%)

Query: 30 SEPPPKIKAFTDKVIQCPLQDIAIPLSGFRWEYGKGNFHHWRPLFLHFDTYFKTYLCSRK 89
SE P KIK+F + V PL+ I PL+ FRWE+ KG+FHHW LF +FDT+F+ ++ RK
Sbjct: 9 SEVPSKIKSFINSVTSVPLELIHEPLACFRWEFDKGDFHHWVDLFNYFDTFFEKHVQVRK 68

Query: 90 DLGLSDNILGDDSPFPKQAVLQILRVMQIILENCHNKGSFSGLE-HFMLLLASTDPEILI 148
DL + +N D PFPK AVLQ+LRV++++LENC NK +S E H LLLASTD +++
Sbjct: 69 DLHIEENFEESDPPFPKDAVLQVLRVIRVVLENCTNKHFYSSYEQHLSLLLASTDADVVE 128

Query: 149 ATLETLAVLVKINPSKLHASGKLVGCGTINSCLLSLAQGWGSKEEGLGLYYCVTVNERSQ 208
A L+TLA +K K + ++NS L SLAQGWG KEEGLGL C
Sbjct: 129 ACLQTLAAFLKRQIGKYS-----IRDASLNSKLFSLAQGWGGKEEGLGLTSCAA------ 177

Query: 209 DEGLSLFPSNVENDGDKSLYHLGSTLYFELHSANAQSNAEAEDGAVSTSMSVINIPDLHV 268
EN D+ LG TL+FE + ++ +S +E G + VI++PD+ +
Sbjct: 178 -----------ENSCDQVSLQLGRTLHFEFYPSD-ESPSELPGG-----LQVIHVPDVSI 220

Query: 269 RKEEDLSLMKFCIEQYNVPPEQRFALLTRIRYAHAFRSPRVCRLYSKICLLAFIVLVQAS 328
E DL L+ + +NVPP RFALLTR+R+A AF S + ++ I L AF+VLVQAS
Sbjct: 221 CAESDLELLNKLVIDHNVPPSLRFALLTRMRFARAFSSLATRQQFTCIRLYAFVVLVQAS 280

Query: 329 DSHDELASFFANEPEYTNELIRIVRSEETISGNVRTLAMNALGAQLAAYASSHERARILS 388
+ + SFF EPE+ NEL+ +V E+T+ +R L + L+ A S +R R +
Sbjct: 281 GDTENVVSFFNGEPEFVNELVTLVSYEDTVPEKIRILCL------LSLVALSQDRTRQPT 334

Query: 389 GSSISFAGGNRMILLNVLQRAIXXXXXXXXXXXXXFVEAVLQFYLLHXXXXXXXXXXXXX 448
+ +GG+R +L ++Q+AI F EA+L +
Sbjct: 335 VLTAVTSGGHRGLLSGLMQKAIDSVVCITSKWSLAFAEALLSLVTV-LVSSSSGCSAMRE 393

Query: 449 XXMVPTFLPLVEDADPAHIHLVCLAVKTLQKLLDYSNAAVTLFKDLGGVELLANRLQIEV 508
++PT +PL++D DP H+HLV AV L+ +DYSN A LF+DLGG++ RL++EV
Sbjct: 394 AGLIPTLVPLIKDTDPQHLHLVSAAVHILEAFMDYSNPAAALFRDLGGLDDTIFRLKLEV 453

Query: 509 HRVIDVAGD----DDNSMVIGEHFKSSEEQI-YSQKRLIRVLLKALGSATYAPANSARSQ 563
R D + D++ E SE I Y ++ L++ LL+A+ TYAP N+
Sbjct: 454 SRTEDDVKEKNCSSDSNGPDTEQLPYSEALISYHRRLLLKALLRAISLGTYAPGNT-NLY 512

Query: 564 GSNDASLPATLCLLFSNVEKFGGDIYSSAVTVMSEIIHKDPTCFPALHELGLPIAFLSSV 623
GS ++ LP LC++F + FGG ++S A TVMS++IHKDPTCF AL GL FL ++
Sbjct: 513 GSEESLLPECLCIIFRRAKDFGGGVFSLAATVMSDLIHKDPTCFNALDSAGLTSTFLDAI 572

Query: 624 VSGILPSPKALTCVPNGLGAICLNPKGLESVKETSALRFLVDIFTNKKYVVAMNEGIVP- 682
++ S +A+TC+P L A+CLN GL++VK+ +ALR V IFT+ Y+ A+ G P
Sbjct: 573 SDEVICSAEAITCIPQCLDALCLNNSGLQAVKDRNALRCFVKIFTSPSYLRALT-GDTPG 631

Query: 683 -LANAVEELLRHVSSLRGTGVDLIIEIVNSIASRGDGEHAESSGK----SSXXXXXXXXX 737
L++ ++ELLRH SSLR GVD+ IEI+NS+ G G A +S +S
Sbjct: 632 SLSSGLDELLRHQSSLRTYGVDMFIEILNSMLIIGSGMEATTSKSADVPTSAAPVPMEID 691

Query: 738 XNRESVASSSLVESTYSSGETISDEQFIQLAVFHVMVLVHRTMENSETCRLFVEKSGIES 797
+ +S+A S E + S + E F+ V +V L ++N+E C LFVEK GI++
Sbjct: 692 VDEKSLAVSDEAEPS-SDTSPANIELFLPDCVCNVARLFETVLQNAEVCSLFVEKKGIDA 750

Query: 798 LLKLLLRPSVAQSSEGMSIALHSTMVFKTFTQHHSAALARAFCSFLKDHLKKALSGFDVV 857
+L+L P + S+ S+ ++ FK F+ HSA LAR CS+L++HLKK +
Sbjct: 751 VLQLFSLPLMPLST---SLGQSFSVAFKNFSPQHSAGLARIVCSYLREHLKKTKILLVSI 807

Query: 858 SGAFMLDPKSTPDRTXXXXXXXXXXXXXAASKDNRWVTALLTEFGNGSKDVLEDIGRIHR 917
G +L +S ++ + ++++E DVL+++G ++
Sbjct: 808 EGTQLLKLESAIQTKILRSLSCLEGMLSLSNFLLKGSASVISELSAADADVLKELGITYK 867

Query: 918 EILWQLALLEESKVD----VEEGSAGATDEARQSELSTTDSEEQRLNSFRQFLDPL---L 970
+ +WQ+AL ++K D V+ GS + + + +D + + R + +P+
Sbjct: 868 QTIWQMALCNDTKEDEKKSVDRGSDNSVSASSSTAERESDEDSSNALAVR-YTNPVSIRS 926

Query: 971 RRRMSGWSFESQFFDLINLYRDL---TRASSIQQRQTTDGPSNVRIEASHQSQQAGSLDD 1027
S W + +F ++ + TR + + R G + +E+ + + + D
Sbjct: 927 SSSQSIWGGDREFLSIVRSGEGIHGRTRHAIARMR---GGRTRRHLESFNFDSEIPA-DL 982

Query: 1028 AGTSNRKEDKQRSYYHSCRDMVKSLSIHITHLFQEMGKVMLLPSRRRDDTLNVSAPSKSV 1087
TS+ E K++S +++ L+ + F + K +RRR D ++S+ SK++
Sbjct: 983 PVTSSSHELKKKSTEVLIAEILNKLNCTLRFFFTALVKGFTSANRRRIDGASLSSASKTL 1042

Query: 1088 ASTFASIAIDHMNFGGH-VTSGSEASVSTKCRYFGKVIEFIDGILLD-KPDSCNAVILNC 1145
+ A + ++ +NF G+ +G E S+S KCRY GKV++ I + D + C ++N
Sbjct: 1043 GTALAKVFLEALNFDGYGAAAGHEKSLSVKCRYLGKVVDDITFLSFDTRRRVCFTAMVNS 1102

Query: 1146 LYGRGVIQSVLTTFEATSQLLFAVNRA-PTSPMETDETHTRQDGVEDADRSWIYGPLGSY 1204
Y G + +LTTFEATSQLL+ V + P S E ++ R + W+ L +Y
Sbjct: 1103 FYVHGTFKELLTTFEATSQLLWTVPFSIPASSTENEKPGERNIW---SHSKWLVDTLQNY 1159

Query: 1205 GKLMDHLATSSLILSPFTK-HLLTQP----LVSGDIPFPQDEETFVKVLQSMVLKTVLPV 1259
+ +D+ S+ +LSP ++ LL QP L G P P++ ETFV+ LQS VL +LP+
Sbjct: 1160 CRALDYFVNSTYLLSPTSQTQLLVQPASVGLSIGLFPVPREPETFVRNLQSQVLDVILPI 1219

Query: 1260 WTHPQFTDCNYDFIAAILNIIRHIYSGVEVKNTNSTAA------RVSGPPPNETTISTIV 1313
W HP F DCN +F+A++ +++ HIYSGV N + R +E+ + IV
Sbjct: 1220 WNHPMFPDCNPNFVASVTSLVTHIYSGVVDARENRSGVTRGINQRALPLQLDESIVGMIV 1279

Query: 1314 EMGFSRNRAEEALRQVGSNSVELAMEWLFSHPEE-VQEDDELARALAMSLGNSGSEAK-E 1371
EMGFSR+RAE ALR+VG+NSVE+AM+WLF++PE+ VQEDDELA+ALA+SLGNS K E
Sbjct: 1280 EMGFSRSRAEIALRRVGTNSVEMAMDWLFTNPEQPVQEDDELAQALALSLGNSSETPKLE 1339

Query: 1372 DVPKESSVTIEEEMVQPPPVDELLSTCRKLLQMKDSLAFPVRDLLVMICSQNDGEHRSAV 1431
D K V EE + PPVDE+++ KL Q DS+AFP+ DL V +C++N GE R +
Sbjct: 1340 DTEKPVDVPQEEAEPKEPPVDEVIAASVKLFQSDDSMAFPLMDLFVTLCNRNKGEDRPKI 1399

Query: 1432 VSFIVEQVKLSS-NVSEDGNRSILSNLFHVLALILNEDTDAREIAAKNGLVNVSSDLLSQ 1490
VS++++Q+KL + S+D L+ + H+LAL+L+ED + REIAA++G+V V+ +L+
Sbjct: 1400 VSYLIQQLKLVQLDFSKD--TGALTMIPHILALVLSEDDNTREIAAQDGIVTVAIGILTD 1457

Query: 1491 W-ISSTFDREKV-PKWVTAAFVAIDRLAQVDQKVNADILEQLKG-----DDATQKSVSIN 1543
+ + S + E + PK ++A + + + Q K++++ +E +G D+ Q S +
Sbjct: 1458 FNLKSESETEILAPKCISALLLVLSMMLQAQTKLSSEYVEGNQGGSLVPSDSPQDSTAAL 1517

Query: 1544 EDKYN------------KLQSSLSTKYLDVQEQKQLVEIACGCMRNQLPSETMHAVLQLC 1591
+D + +L ST YL ++E + + IACG ++ +P+ M AVLQLC
Sbjct: 1518 KDALSSDVAKGESNQALELIFGKSTGYLTMEEGHKALLIACGLIKQHVPAMIMQAVLQLC 1577

Query: 1592 ATLTRTHSVAVNXXXXXXXXXXXXXXXXXXFIGFDNIAATIIRHVLEDPQTLQQAMEAEI 1651
A LT++H++A+ F G+D +A+ I+RH++EDPQTLQ AME EI
Sbjct: 1578 ARLTKSHALAIQFLENGGLSSLFNLPKKCCFPGYDTVASVIVRHLVEDPQTLQIAMETEI 1637

Query: 1652 RHNVVSASNRQSSGRLTPRNFLLNLTSVIQRDPVIFMRAAHSVCQVEMVGERPYVVLLXX 1711
R + S ++ GR+ PR FL + VI RDPV+FM+A S CQ+E G R +V+L
Sbjct: 1638 RQTL---SGKRHIGRVLPRTFLTTMAPVISRDPVVFMKAVASTCQLESSGGRDFVILSKE 1694

Query: 1712 XXXXXXXXXXXXXXXXXXXXMQNADLXXXXXXXXXXXXXXXLDASSKNVKVHRKPPHSFV 1771
+ L D S K K HR+ P +F+
Sbjct: 1695 KEKPKVSGSEHGFSLNEPLGISENKLH---------------DVSGKCSKSHRRVPANFI 1739

Query: 1772 SVIELLLDPVVKFVPSLKDEPATKENLGSTDMEIDXXXXXXXXXXXXXXXXXXXXDN--- 1828
VI+ L+D V+ F P +K + + NL S ME+D
Sbjct: 1740 QVIDQLIDLVLSF-PRVKRQEDGETNLIS--MEVDEPTTKVKGKSKVGEPEKASSSRVGE 1796

Query: 1829 ------HELSAYMAKIVFILKLLTEILLMYTASVHILIRKDSEVSSCIAVPLRTGHLA-- 1880
E S +A++ FILKLL++I+LMY+ +++R+D+E+S LR +L
Sbjct: 1797 PEKAEIPEKSEELARVTFILKLLSDIVLMYSHGTSVILRRDTEISQ-----LRGSNLPDD 1851

Query: 1881 ----GGIFHHILHKFLPYTKSSKKERKTDVDWRQKLSSRASQFLVASCVRSTEARKRIFT 1936
GG+ +H++H+ LP S ++ +W++KLS +AS FLV C RS E RKRI
Sbjct: 1852 SPGNGGLIYHVIHRLLPI---SLEKFVGPEEWKEKLSEKASWFLVVLCSRSNEGRKRIIN 1908

Query: 1937 EINSVFSDFVEFG----SGFRAPGIEIQAFIDLLSDVLTARAPT------GSSISAEASA 1986
E++ V S F G P + AF +L+ +LT + + G S + +
Sbjct: 1909 ELSRVLSVFASLGRSSSKSVLLPDKRVLAFANLVYSILTKNSSSSSSNFPGCGCSPDVAK 1968

Query: 1987 TFIDVGLVQSLTRALHVLDLDHTDSSK 2013
+ +D G +Q LT LHV+DLDH D+ K
Sbjct: 1969 SMMDGGTIQCLTSILHVIDLDHPDAPK 1995



Score = 875 bits (2260), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 455/718 (63%), Positives = 523/718 (72%), Gaps = 19/718 (2%)

Query: 2941 PGTSSTEQLTGPPIQSAAEMNTESHAASSEVEDKSGASSSVASRDQSTXXXXXXXX--XX 2998
P + E+L P+ A T A S V + A SVA R
Sbjct: 2976 PSSGVPEKLENKPVGEEASSETRKDAESELVGE---ADLSVARRKNCAEIYNIFLQLPQS 3032

Query: 2999 XXXXXCSLLAREGLSDNAYSLVAEVLKKLVAIAPAICHLFITELAGSVQSLTRSAMDELN 3058
C LL EGLSD YSL EVLKKL A+ A F EL+ SL+ S + EL
Sbjct: 3033 DLCNLCILLGYEGLSDKIYSLAGEVLKKLAAVDVAHRKFFTKELSELASSLSSSTVRELA 3092

Query: 3059 KFREVEKALLSTTSTDGAVILRVLQALSSLVASIGDKNNENQIISEKEHGATISLVWDIN 3118
+K ST S GA ILRVLQ LSSL + I D++N ++ I + +N
Sbjct: 3093 TLSSKQKMSRSTGSMAGASILRVLQVLSSLTSPI-DESNVGTERETEQEEQNI--MQRLN 3149

Query: 3119 TALEPLWQELSTCISTIE---SFSETAPNLPRSSIVTSSKPAGAMPPLPAGTQNILPYIE 3175
ALEPLW ELS CIS E + A N+ V P ++ P GTQ +LP IE
Sbjct: 3150 VALEPLWHELSQCISMTELQLDHTAAASNINPGDHVLGISPTSSLSP---GTQRLLPLIE 3206

Query: 3176 SFFVMCEKLH-PGHLGAGQEFSIATVPDPEEATASAMQPKTPTSATKVDEKHIAFVKFAE 3234
+FFV+CEK+ P L Q+ + T + +E++A KT + K + + F KFAE
Sbjct: 3207 AFFVLCEKIQTPSML---QQDTNVTAGEVKESSAHGSSSKTSVDSQKKTDGSVTFSKFAE 3263

Query: 3235 KHKKLLNAFVRQNPGLLEKSFSIMLKVPRFVDFDNKRSYFRSKIKHQHDHHHS-PLRISV 3293
KH++LLN+F+RQNP LLEKS S+MLK PR +DFDNK++YFRS+I+HQHD H S PLRISV
Sbjct: 3264 KHRRLLNSFIRQNPSLLEKSLSMMLKAPRLIDFDNKKAYFRSRIRHQHDQHISGPLRISV 3323

Query: 3294 RRAYILEDSYNQLRMRTTQELKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLF 3353
RRAY+LEDSYNQLRMR+ Q+LKGRL V FQGEEGIDAGGLTREWYQLLSRVIFDKGALLF
Sbjct: 3324 RRAYVLEDSYNQLRMRSPQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLF 3383

Query: 3354 TTVGNEATFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGAKVT 3413
TTVGN+ATFQPNPNSVYQTEHLSYFKFVGR+V KALFDGQLLDV+FTRSFYKHILG KVT
Sbjct: 3384 TTVGNDATFQPNPNSVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVKVT 3443

Query: 3414 YHDIEAIDPDYFKNLKWLLENDISDILDLTFSIDADEEKLILYERNEVTDYELIPGGRNI 3473
YHDIEA+DPDY+KNLKWLLEND+SDILDLTFS+DADEEK ILYE+ EVTDYEL PGGRNI
Sbjct: 3444 YHDIEAVDPDYYKNLKWLLENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNI 3503

Query: 3474 RVTEENKQQYVDLVAEHRLTTAIRPQINAFLEGFSELIPRELISIFHDKELELLISGLPD 3533
RVTEE K +YVDLVA H LT AIRPQINAFLEGF+ELIPREL+SIF+DKELELLISGLP+
Sbjct: 3504 RVTEETKHEYVDLVAGHILTNAIRPQINAFLEGFNELIPRELVSIFNDKELELLISGLPE 3563

Query: 3534 IDLDDLRANTEYSGYSPASPVIQWFWEVVQAFSKEDKARLLQFVTGTSKVPLEGFSALQG 3593
ID DDL+ANTEY+ Y+ SPVI WFWEVV+AFSKED AR LQFVTGTSKVPLEGF ALQG
Sbjct: 3564 IDFDDLKANTEYTSYTAGSPVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQG 3623

Query: 3594 ISGSQKFQIHKAYGSADHLPSAHTCFNQLDLPEYPSKEHLEERLLLAIHEANEGFGFG 3651
ISG Q+ QIHKAYG+ + LPSAHTCFNQLDLPEY SKE L+ERLLLAIHEA+EGFGF
Sbjct: 3624 ISGPQRLQIHKAYGAPERLPSAHTCFNQLDLPEYQSKEQLQERLLLAIHEASEGFGFA 3681



Score = 264 bits (675), Expect = 6e-69, Method: Compositional matrix adjust.
Identities = 236/724 (32%), Positives = 348/724 (48%), Gaps = 110/724 (15%)

Query: 2228 LRLGDGMNGINVFDHIEVFGRE-------HSLSSETLHVMPVE-VFGSRR----QGRTTS 2275
+R + ++G+ DH ++ GR +++E + V+ +F RR + R +
Sbjct: 2199 VRWREALDGL---DHFQILGRSGGGNGFIDDITAEPFEGVNVDDLFALRRPLGFERRRQT 2255

Query: 2276 IYNLLGRGGDSIAPSQHPLLVEPSSLLQLGQPRQSESIRDAYSDRSSEGT---------- 2325
+ L R G + QHPL PS Q G + + S S G+
Sbjct: 2256 GRSSLDRSGSEVHGFQHPLFSRPS---QTGNTASVSASAGSISRHSEAGSYDVAQFYMFD 2312

Query: 2326 --------------SSRL----------DSVFRSLRSSRHGQRFNFWTNDNQQSGGSGAS 2361
S+RL D + SSR G + WT+ S ++
Sbjct: 2313 TPVLPFDQVPVDPFSARLAGGGAPPPLTDYSVVGMDSSRRGVGDSRWTDIGHPQPSSLSA 2372

Query: 2362 ALPQGFEDLLVSHLRRPSPEKSADQDATEGSQNRGE----------ATQFVGSGEMAAES 2411
++ Q E+ +S+LR +P + + T ++ + + + +G G +
Sbjct: 2373 SIAQLIEEHFISNLRASAPVNTVVERETNTTEIQEQLHPDVPPSVGSETVLGDGNEGGQQ 2432

Query: 2412 AMENNNINEARDASTPSTVLDESGGANVTPVANVSSQGTDAPSSQ---SQPVEMQFEQND 2468
+ E +N + + P V+ ES +A+ SQ T Q QP+ + N+
Sbjct: 2433 SEERELLNNNENVNNPPDVMAESFAQGQANLASPVSQDTGESLQQLEVMQPLPLNSTPNE 2492

Query: 2469 VAIRDV-------------EAVSQESSGSGATLGESLRSLDVEIGSADGHDDGGDRQGSA 2515
+ +V EAV S+ G S++++ V + D + Q S
Sbjct: 2493 IDRMEVGEGDGAPIDQVDHEAVHLISTAQGQPDTSSIQNVSVTAIAPPVDDPDSNFQPSV 2552

Query: 2516 DARIRRTNVSFGNSTQVSARDVALHSVSEASEHPNQEAEQSGPNDEQQRNVDADS----- 2570
D + S Q S D + +E + EA ++ NDEQ D
Sbjct: 2553 DVDMSSDGAEGNQSVQPSPLD------GDNNELSSMEATENVRNDEQVEEGSLDGRAPEV 2606

Query: 2571 GSIDPAFLEALPEELRAEVLSAQQGQATQPPNSEPQNGGDIDPEFLAALPSDIREEVXXX 2630
+IDP FLEALPE+LRAEVL++QQ Q+ QPP EP DIDPEFLAALP DI+ EV
Sbjct: 2607 NAIDPTFLEALPEDLRAEVLASQQAQSVQPPTYEPPPVDDIDPEFLAALPPDIQTEVLAQ 2666

Query: 2631 XXXXXXXXSQELEGQPVEMDTVSIIATFPSELREEVLLTSSDAILANLTPALVAEANMLR 2690
Q+ +GQ V+MD SIIAT P++LREEVLLTSS+A+LA L L+AEA MLR
Sbjct: 2667 QRAQRMV--QQSQGQAVDMDNASIIATLPADLREEVLLTSSEAVLAALPSPLLAEAQMLR 2724

Query: 2691 ERFARRYN--RTLFGMYPRSRRGDSRRN-------EQLDRA-GGTLSRRSA-----GSKP 2735
+R Y ++FG S R ++RRN +DR G T+ +R+ G K
Sbjct: 2725 DRAMSHYQARSSVFG---SSHRLNNRRNGLGYNRLTGMDRGVGVTIGQRAVSSSADGLKV 2781

Query: 2736 LEADGSPLVDTEGLRALVRLLRVFQPIYKVPLQRLMLNLSAHAETRTALVKIFMDLLMLD 2795
E +G PLV+ + L++L+RLLR+ QP+ K LQRL+LNL AH+ TR LV++ +D++ +
Sbjct: 2782 KEIEGDPLVNADALKSLIRLLRLAQPLGKGLLQRLLLNLCAHSFTRANLVQLLLDMIRPE 2841

Query: 2796 VGQPANDLNTAEPPYRLYGCQSNVMYSRPQHLDGIPPLLSRRVLETLTYLAKNHSLVAKT 2855
+ ++L P RLYGCQSNV+Y R Q L+G+PPL+ RRVLE LTYLA NHS VA
Sbjct: 2842 METSPSELAITN-PQRLYGCQSNVVYGRSQLLNGLPPLVFRRVLEVLTYLATNHSAVADM 2900

Query: 2856 LLEF 2859
L F
Sbjct: 2901 LFYF 2904

Query: CNT0015141
Subject: sp|O13834|PTR1_SCHPO E3 ubiquitin-protein ligase ptr1

OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A /
CBS 708.71 / DSM 1257 / FGSC 987) GN=B11B22.010 PE=3 SV=4

 Score =  504 bits (1299), Expect = e-142,   Method: Compositional matrix adjust.
Identities = 276/669 (41%), Positives = 390/669 (58%), Gaps = 74/669 (11%)

Query: 3006 LLAREGLSDNAYSLVAEVLKKLVAIAPAICHLFITELAGSVQSLTRSAMDELN------- 3058
+ARE S + +K L I P +F EL + L+ + + +L+
Sbjct: 3459 FVARE-CSSKTFQNTISTIKNLSNI-PGAKKVFGDELVRQARVLSENILSDLDNLLPHIL 3516

Query: 3059 ------KFREVEKALLSTTSTDGAVILRVLQALSSLVASIGDKNNENQIISEKEHGATIS 3112
+ + V A S +++ +LRVL AL L S K ++ + S
Sbjct: 3517 KAESGTQIQGVALAKFSPGASEQNKLLRVLTALDHLFDSKSKKQDKPAEGENTKEDLLGS 3576

Query: 3113 LVWDINTALEPLWQELSTCISTIESFSETAPNLPRSSIVTSSKPAGAMPPLPAGTQNILP 3172
L W N +W +LS C+S I R +++ + +LP
Sbjct: 3577 LYW--NPTFGKMWDKLSACLSAIRQ---------RDNMLNVAT-------------ILLP 3612

Query: 3173 YIESFFVMCEKLHPGHLGA-----GQEFSIATVPDPEEATASAMQPKTPTSATKVDEKHI 3227
IES V+C+ A Q+ + T P PE+ A
Sbjct: 3613 LIESLMVVCKNTTLSDASAVSNANSQKEMLLTSPPPEDRIAG------------------ 3654

Query: 3228 AFVKFAEKHKKLLNAFVRQNPGLLEKSFSIMLKVPRFVDFDNKRSYFRSKI--KHQHDHH 3285
F F E+H+++LN VR NP L+ +FS+++K P+ ++FDNKR+YF + K+Q H
Sbjct: 3655 LFFTFTEEHRRILNELVRHNPKLMSGTFSLLVKNPKVLEFDNKRNYFNRSVHSKYQQTRH 3714

Query: 3286 -HSPLRISVRRAYILEDSYNQLRMRTTQELK-GRLTVHFQGEEGIDAGGLTREWYQLLSR 3343
PL++ VRR ++ DS+ L + ELK G+L + FQGEEG+DAGG+TREW+Q+LSR
Sbjct: 3715 SFPPLQLQVRREHVFHDSFRSLYYKKADELKFGKLNIRFQGEEGVDAGGVTREWFQVLSR 3774

Query: 3344 VIFDKGALLFTTVGNE-ATFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRS 3402
+FD +LF V ++ TF PN S EHL +FKF+GR++GKAL++G+LL+ +F+R+
Sbjct: 3775 QMFDPNYVLFVPVSSDRTTFHPNKLSPINDEHLPFFKFIGRIIGKALYEGRLLECYFSRA 3834

Query: 3403 FYKHILGAKVTYHDIEAIDPDYFKNLKWLLENDISDILDLTFSIDADEEKLILYERNEVT 3462
YK ILG V+ D+E+ DPDY+K+L W+LENDI+DI+ TFS++ D EV
Sbjct: 3835 VYKRILGKPVSVKDMESFDPDYYKSLVWMLENDITDIITETFSVEDD-------VFGEVK 3887

Query: 3463 DYELIPGGRNIRVTEENKQQYVDLVAEHRLTTAIRPQINAFLEGFSELIPRELISIFHDK 3522
+LI GRNI VTEENK +YV L+ EH+L T+++ Q+ AFL GF E+IP ELI+IF+++
Sbjct: 3888 VVDLIENGRNIPVTEENKHEYVRLIVEHKLITSVKDQMKAFLTGFHEIIPEELIAIFNEQ 3947

Query: 3523 ELELLISGLPDIDLDDLRANTEYSGYSPASPVIQWFWEVVQAFSKEDKARLLQFVTGTSK 3582
ELELLISGLPDID+DD +ANTEY YS +P IQWFW V++F KE+ A+LLQFVTGTSK
Sbjct: 3948 ELELLISGLPDIDIDDWKANTEYHNYSAGAPQIQWFWRAVRSFDKEELAKLLQFVTGTSK 4007

Query: 3583 VPLEGFSALQGISGSQKFQIHKAYGSADHLPSAHTCFNQLDLPEYPSKEHLEERLLLAIH 3642
VPL GF L+G++G +F IH+ YGS D LPS+HTCFNQLDLPEY + E L +LL AI
Sbjct: 4008 VPLNGFKELEGMNGVSRFNIHRDYGSKDRLPSSHTCFNQLDLPEYENYETLRSQLLKAIT 4067

Query: 3643 EANEGFGFG 3651
++ FGF
Sbjct: 4068 AGSDYFGFA 4076



Score = 78.2 bits (191), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 86/269 (31%), Positives = 120/269 (44%), Gaps = 52/269 (19%)

Query: 2548 HPNQEAEQSGP--NDEQQ------------RN--VDADSGSIDPAFLEALPEELRAEVL- 2590
HP + E GP N EQQ RN +D ID +LEALPEE R EV+
Sbjct: 2935 HPMEGVETQGPGENAEQQAEDERPRVYYTLRNQQIDITELGIDAEYLEALPEEFRDEVIA 2994

Query: 2591 ---SAQQGQATQPPNSEPQNGGDIDPEFLAALPSDIREEVXXXXXXXXXXXSQE--LEGQ 2645
S ++ QA + + E +N ++ EFL ALP ++R E+ ++ GQ
Sbjct: 2995 QAISTRRSQAREQVSQEGENT-EVFQEFLEALPEELRNEILHQEQHEQRRRERQNAAGGQ 3053

Query: 2646 ---PVEMDTVSIIATFPSELREEVLLTSSDAILANLTPALVAEANMLRERFARRYNRTLF 2702
P +MD SI+ TFP LR++VLL + I+ +L P L AEA RTL
Sbjct: 3054 DLGPADMDPASILLTFPPGLRQQVLLDQGEDIMEHLGPELAAEA------------RTLV 3101

Query: 2703 GMYPRSRRGDSRRNEQLDRAGGTLSRRSAGSKPLEADGSPLVDTEGLRALVRLLRVFQPI 2762
+ R + G SR +P EA G+ V R +V++L Q I
Sbjct: 3102 ARH---------RQLHAQQGGQAASRSRDAQRPTEA-GAGTVQKIQKRTVVQMLDK-QGI 3150

Query: 2763 YKVPLQRLMLNLSAHAETRTALVKIFMDL 2791
L RLM +S R++L IF +L
Sbjct: 3151 --ATLLRLMF-VSQQGSIRSSLFSIFANL 3176

Query: CNT0015141
Subject: sp|Q756G2|TOM1_ASHGO Probable E3 ubiquitin-protein ligase TOM1

OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
GN=ptr1 PE=1 SV=1

 Score =  473 bits (1216), Expect = e-132,   Method: Compositional matrix adjust.
Identities = 250/595 (42%), Positives = 364/595 (61%), Gaps = 64/595 (10%)

Query: 3062 EVEKALLSTTSTDGAVILRVLQALSSLVASIGDKNNENQIISEKEHGATISLV--WDINT 3119
+V A S++ A +LR L+AL I ++ + Q E+ G I L+ +D N
Sbjct: 2692 QVALAPFCPASSNQAKLLRCLKALDY----IFERRPKGQ---EQSPGNIIQLLEFYD-NL 2743

Query: 3120 ALEPLWQELSTCISTIESFSETAPNLPRSSIVTSSKPAGAMPPLPAGTQNILPYIESFFV 3179
LW+ LS C+S + +SI S +LP IES V
Sbjct: 2744 KFSSLWEVLSECLSALRD---------HTSITHVSTV-------------LLPLIESLMV 2781

Query: 3180 MCEKLHPGHLGAGQEFSIATVPDPEEATASAMQPKTPTSATKVDEKHIAFVKFAEKHKKL 3239
+C + + PE+ + P T F+ F E+H+K+
Sbjct: 2782 ICR--------------LVFIELPEDV-GKHISPILERFKT-------LFISFTEEHRKI 2819

Query: 3240 LNAFVRQNPGLLEKSFSIMLKVPRFVDFDNKRSYFRSKIKHQH-DHHHSPLRISVRRAYI 3298
+N V P L+ SFS+++K P+ ++F+NKR+YF ++ + + PL I+VRR ++
Sbjct: 2820 INMMVFTTPSLMSGSFSLLVKNPKVLEFENKRNYFNRQLHEEAAKEQYPPLNITVRRDHV 2879

Query: 3299 LEDSYNQLRMRTTQELK-GRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTV- 3356
DSY L + E+K +L +HF+ EEG+DAGG+TREW Q+L+R +F+ LF V
Sbjct: 2880 FLDSYRALHFKDADEVKFSKLNIHFRDEEGVDAGGVTREWLQVLARQMFNPDYALFLPVT 2939

Query: 3357 GNEATFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGAKVTYHD 3416
G+ TF PN +S +HLS+FKF GR++GKAL+DG+LLD HF+R+ YKH+L V+ D
Sbjct: 2940 GDATTFHPNRDSSVNPDHLSFFKFTGRIIGKALYDGRLLDCHFSRAVYKHMLHRSVSVKD 2999

Query: 3417 IEAIDPDYFKNLKWLLENDISDILDLTFSIDADEEKLILYERNEVTDYELIPGGRNIRVT 3476
IE++DPDY+K+L W+L NDI+DI+ F+++ D ++ V D LIP GRNI VT
Sbjct: 3000 IESLDPDYYKSLVWMLNNDITDIITEEFAVEKD-----VFGEKTVVD--LIPNGRNIPVT 3052

Query: 3477 EENKQQYVDLVAEHRLTTAIRPQINAFLEGFSELIPRELISIFHDKELELLISGLPDIDL 3536
E NKQ YV+ + +++L +++ Q+ + L+GFS++IP LI IF+++ELELLISGLP+ID+
Sbjct: 3053 ELNKQNYVNRMVDYKLRESVKDQLKSLLDGFSDIIPSHLIQIFNEQELELLISGLPEIDI 3112

Query: 3537 DDLRANTEYSGYSPASPVIQWFWEVVQAFSKEDKARLLQFVTGTSKVPLEGFSALQGISG 3596
DD + NTEY GY+ +SP +QWFW V++F +E++A+LLQF TGTSKVPL GF L+G+SG
Sbjct: 3113 DDWKNNTEYHGYNVSSPQVQWFWRAVRSFDEEERAKLLQFATGTSKVPLNGFKELEGMSG 3172

Query: 3597 SQKFQIHKAYGSADHLPSAHTCFNQLDLPEYPSKEHLEERLLLAIHEANEGFGFG 3651
Q+F IHK+YGS + LP +HTCFNQLDLPEY + E L LL AI+E +EGFGF
Sbjct: 3173 FQRFNIHKSYGSLNRLPQSHTCFNQLDLPEYDTYEQLRSMLLTAINEGSEGFGFA 3227



Score = 125 bits (315), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 158/711 (22%), Positives = 299/711 (42%), Gaps = 68/711 (9%)

Query: 30 SEPPPKIKAFT----DKVIQCPLQDIAIPLSGFR---WEYGKGNFHHWRPLFLHFDTYFK 82
S+PPP++ F ++ + L +++ S FR W Y +G+ + W P+ FD +
Sbjct: 13 SQPPPRVAEFIRQAQNEEVTSDLGLVSL-CSEFRKNDWPYPRGDLYSWVPVLNRFDAILE 71

Query: 83 TYLCSRKDLGLSDNILGDDSPFPKQAV---LQILRVMQIILENCHNKGSFSGLEHFMLLL 139
+ + L D + PF + L+IL +L +C N+ ++ + LL
Sbjct: 72 RIV---EHYSLKDKV--QTKPFDSDTLSILLEILSFSAHLLSHCANRSIYNSTVYLEYLL 126

Query: 140 ASTDPEILIATLETLAVLV-KINPSKLHASGKLVGCGTINSCLLSLAQ-----GWGSKEE 193
S+ E++ +TL L +V K SK + + L+ L Q G+ E
Sbjct: 127 NSSVLEVIDSTLALLLHIVQKATISKRGKQLFSLSQDRLFRFLMFLPQDAMKTGFSQNYE 186

Query: 194 GLGLYYCVTVNERSQDEGLSLFPSNVENDGDKSLYHLGSTLYFELHSANAQSNAEAEDGA 253
L + NE Q E SL S ++ K S+ +Q N+E
Sbjct: 187 TL-----LFSNEIPQ-EWCSLELSYYKSSPSKDF------------SSASQPNSEG---- 224

Query: 254 VSTSMSVINIPDLHVRKEEDLSLMKFCIEQYNVPPEQRFALLTRIRYAHAFRSPRVCRLY 313
S++ +P V + L+ + +P + F LL + RL
Sbjct: 225 ----FSILKLPYNKVLGKPIEELLVKTLHDNQIPEQYSFDLLVSLMLRQNLYDINRRRLM 280

Query: 314 SKICLLAFIVLVQASDSHDELASFFANEPEYTNELIRIVRSEETISGNVRTLAMNALGAQ 373
+I LLA LV A S F +PE T L +V + + N + + A
Sbjct: 281 IRIGLLALSNLVYAH-SQAVQTRFLIADPEITTHLANLVSPDVDLPQNFKAVCFECFKA- 338

Query: 374 LAAYASSHERARILSGSSISFAGGNRMILLNVLQRAIXXXXXXXXXXXXXFVEAVLQF-- 431
+ +L+ ++S + G +++N+++ +V++ F
Sbjct: 339 --FFFKKSMIPSVLASLNVSVSYG---LMMNLVRDFSKNLENPNFYYEREYVDSFYDFLQ 393

Query: 432 YLLHXXXXXXXXXXXXXXXMVPTFLPLVEDADPAHIHLVCLAVKTLQKLLDYSNAAVTLF 491
++ ++ L + P ++V ++ L L+D + A F
Sbjct: 394 FMTSSPLGGNMACSAGLTSLLGYHLSV---KTPQATYVVARSIVMLDHLIDGYSMAFPDF 450

Query: 492 KDLGGVELLANRLQIEVHRVI-DV-AGDDDNSMVIGEHFKSSEEQIYSQKRLIRVLLKAL 549
+ G+++L +R+Q E+ + D+ +G + +V+ + S ++ + K L++ +L +
Sbjct: 451 SESKGLDMLVDRVQYELEAGLQDIKSGKGNPEIVLNMDYAISYDRYFLLKNLLKFVLHLI 510

Query: 550 GSATYAPANSARSQGSNDASLPATLCLLFSNVEKFGGDIYSSAVTVMSEIIHKDPTCFPA 609
S + + D+SL ++L L + E +G ++++S +MS IH +PTC+
Sbjct: 511 QSG----GSVVELRNLIDSSLISSLAFLLEHHEVYGSNLFASTTNIMSTFIHNEPTCYGI 566

Query: 610 LHELGLPIAFLSSVVSGILPSPKALTCVPNGLGAICLNPKGLESVKETSALRFLVDIFTN 669
+HE L AFL +V IL S A+T +P GAICLN +G + E + + L IFT+
Sbjct: 567 IHEKKLSHAFLDAVNRKILNSSDAITSIPLAFGAICLNSQGFDLFLEKNPIPQLFSIFTS 626

Query: 670 KKYVVAM--NEGIVPLANAVEELLRHVSSLRGTGVDLIIEIVNSIASRGDG 718
+ ++ ++ L ++EL+RH SL+ V +I + + +++ D
Sbjct: 627 LNHCKSLISSDNAAILGTYIDELMRHQPSLKDPIVKMIFKACDQVSALLDN 677



Score = 51.6 bits (122), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/64 (46%), Positives = 37/64 (57%), Gaps = 2/64 (3%)

Query: 2564 RNVDADSGSIDPAFLEALPEELRAEVLSAQQGQATQPPNSEPQNGGDIDPEFLAALPSDI 2623
R VD S IDP FL ALPEE+R EV+ Q + S + IDP FL LPSD+
Sbjct: 2258 REVDVSSLGIDPTFLLALPEEMREEVVF--QHIQERHMESISDSSRRIDPSFLEVLPSDL 2315

Query: 2624 REEV 2627
R+E+
Sbjct: 2316 RDEL 2319

Query: CNT0015141
Subject: sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo

OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) GN=TOM1 PE=3 SV=2

 Score =  456 bits (1172), Expect = e-127,   Method: Compositional matrix adjust.
Identities = 243/586 (41%), Positives = 352/586 (60%), Gaps = 58/586 (9%)

Query: 3068 LSTTSTDGAVILRVLQALSSLVASIGDKNNENQIISEKEHGATISLVWDINTALEPLWQE 3127
+ S+D + +L+VL A+ + + K E Q++ + L L +W
Sbjct: 2729 FTVPSSDQSKLLKVLTAIDYIY--VNRKKEEEQVVDQL-------LPLYNKMELGHIWVS 2779

Query: 3128 LSTCISTIESFSETAPNLPRSSIVTSSKPAGAMPPLPAGTQNILPYIESFFVMCEKLHPG 3187
LS C++ E P + S+ + +LP IES V+C+
Sbjct: 2780 LSNCLTRFEE----KPRMSTSATI------------------LLPLIESLMVVCKH---- 2813

Query: 3188 HLGAGQEFSIATVPDPEEATASAMQPKTPTSATKVDEKHIAFVKFAEKHKKLLNAFVRQN 3247
+ V + ++A K + T V+ F F + HKKLLN +R N
Sbjct: 2814 ----------SKVRETKDALLKYEAKKCDFARTPVEN---LFFAFTDLHKKLLNEMIRSN 2860

Query: 3248 PGLLEKSFSIMLKVPRFVDFDNKRSYFRSKIKHQHDHHHSPLRISVRRAYILEDSYNQLR 3307
P L+ FS+++K P+ +DFDNKR YF ++++ H L ISVRR ++ DSY L
Sbjct: 2861 PKLMSGPFSLLVKNPKILDFDNKRYYFTAQLR-AITHDRPKLSISVRREHVFLDSYRSLF 2919

Query: 3308 MRTTQELK-GRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NEATFQPN 3365
++ +++K +L + F+GE G+DAGG+TREWYQ+LSR +F+ LF V ++ TF+PN
Sbjct: 2920 FKSNEDIKISKLEISFKGEAGVDAGGITREWYQVLSRQMFNPDYALFIPVASDKTTFRPN 2979

Query: 3366 PNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGAKVTYHDIEAIDPDYF 3425
S EHLS+FKF+G ++GKA+ D LD HF+R YK+ILG V D+E++D DY+
Sbjct: 2980 RTSGINPEHLSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGKPVALKDMESLDLDYY 3039

Query: 3426 KNLKWLLENDISDILDLTFSIDADEEKLILYERNEVTDYELIPGGRNIRVTEENKQQYVD 3485
K+L W+LENDI+DI++ TFS++ D+ Y ++V ELI G ++ VTE+NK YV
Sbjct: 3040 KSLIWILENDITDIIEETFSVETDD-----YGEHKVI--ELIENGAHVAVTEQNKHDYVK 3092

Query: 3486 LVAEHRLTTAIRPQINAFLEGFSELIPRELISIFHDKELELLISGLPDIDLDDLRANTEY 3545
+ E++L T+++ Q+ FL+GF +IP++LISIF ++ELELL+SGLPDID+DD + NT Y
Sbjct: 3093 KIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELLVSGLPDIDVDDWKNNTIY 3152

Query: 3546 SGYSPASPVIQWFWEVVQAFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKA 3605
Y+P I +FW V++F KE++A+LLQFVTGTSKVPL GF L G++G KF IH+
Sbjct: 3153 VNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHRD 3212

Query: 3606 YGSADHLPSAHTCFNQLDLPEYPSKEHLEERLLLAIHEANEGFGFG 3651
YGS D LPS+HTCFNQLDLP Y S E L LLLAI+E +EGFG
Sbjct: 3213 YGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFGIA 3258



Score = 60.8 bits (146), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 40/147 (27%), Positives = 68/147 (46%), Gaps = 2/147 (1%)

Query: 577 LFSNVEKFGGDIYSSAVTVMSEIIHKDPTCFPALHELGLPIAFLSSVVSGILPSPKALTC 636
+ N FG + S A+ V+ II+ +PT + L E G L + + P+ L
Sbjct: 546 ILENRPVFGYTLVSHALDVVQTIINTEPTIYQVLVESGTIPYILQNFDQFLGPTSDLLCM 605

Query: 637 VPNGLGAICLNPKGLESVKETSALRFLVDIFTNKKY--VVAMNEGIVPLANAVEELLRHV 694
+P + AICLN GL+ VKE + L++L + ++ +++ + V A++EL RH
Sbjct: 606 LPEVISAICLNTDGLKQVKEKNLLKYLFQVIKTPEFAKILSWEDQAVNYGVALDELARHY 665

Query: 695 SSLRGTGVDLIIEIVNSIASRGDGEHA 721
L+ D V + S H+
Sbjct: 666 PELKPLIEDYFAATVKELPSLTSYTHS 692



Score = 55.5 bits (132), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 63/242 (26%), Positives = 104/242 (42%), Gaps = 37/242 (15%)

Query: 2585 LRAEVLSAQQGQATQPP-----NSEPQN--GGDIDPEFLAALPSDIREEVXXXXXXXXXX 2637
+ A +++ Q +A Q P + E N G D+D EFL ALP DIR EV
Sbjct: 2302 IEAPGINSPQARAPQEPVYVTIDGEAVNIAGTDMDAEFLNALPDDIRAEVFAQHIREYRT 2361

Query: 2638 XSQELEGQPVEMDTVSIIATFPSELREEVLLTSSDAILANLTPALVAEANMLRERFARRY 2697
Q EG E+D + T P LR+E+ L + N P+++ N E F+
Sbjct: 2362 QFQGSEGSSRELDA-GFLNTIPETLRQEI-LAQEVPLERNARPSILGLRNREGEEFSEVE 2419

Query: 2698 NRTLFGMYPRSRRGDSRRNEQLDRAGGTLSRRSAGSKPLEADGSPLVDTEGLRALVRLLR 2757
+ + R NEQ + T + R +PL+D G+ A+++ +
Sbjct: 2420 DES------------PRFNEQRTESSKTKTDR--------VHFAPLLDRSGIAAIMKAVF 2459

Query: 2758 VFQP-IYKVPLQRLMLNLSAHAETRTALVKIFMDLLMLDVGQPANDLNTAEPPYRLYGCQ 2816
+ QP + + L L + + R+ + M++L+L + ND ++ E R+Y
Sbjct: 2460 IPQPYLSREIYHELFYRLCSSKQNRSDI----MNMLLLILMDGINDQHSLE---RVYNLL 2512

Query: 2817 SN 2818
SN
Sbjct: 2513 SN 2514