Query: CNT0016063
Subject: sp|Q96CN4|EVI5L_HUMAN EVI5-like protein OS=Homo sapiens GN=EVI5LOS=Drosophila melanogaster GN=Evi5 PE=1 SV=3
Score = 202 bits (514), Expect = 7e-57, Method: Compositional matrix adjust.
Identities = 110/290 (37%), Positives = 176/290 (60%), Gaps = 14/290 (4%)
Query: 63 SDWKQYVRRKPHVVKRRIRKGIPDCLRGLVWQLISGSRDLLLLNPGVYEQLVIY--ETSA 120
+DW+ ++RK V +R+GIP R +VWQ +SG+ D G +Q Y TSA
Sbjct: 96 NDWEGALKRKNPCVSELVRRGIPHHFRAIVWQQLSGASD------GDKKQYAEYIKATSA 149
Query: 121 SELDIIRDISRTFPSHVFFQQRHGPGQRSLYNVLKAYSVFDRDVGYVQGMGFVAGLLLLY 180
E I RDI+RT+P FF+++ GPGQ +L+NV+KAYS+ DR+VGY QG GF+ GLLL+
Sbjct: 150 CEKVIRRDIARTYPEVEFFKEKDGPGQEALFNVIKAYSLHDREVGYCQGSGFIVGLLLMQ 209
Query: 181 MSEEDAFWLLVALLKGAVHTPMEGMYLVGLPLVQQYLFQFDHLVKEHMPKLGEHFAQEMI 240
M EE+AF +LV +++ M M+ + + ++Q ++LV+E +P + HF Q+
Sbjct: 210 MPEEEAFAVLVQIMQ---QHRMRHMFKPSMSELGLCMYQLENLVQEQIPDMHIHFQQQGF 266
Query: 241 NPSMYASQWFITVFSYSFPFHLALRIWDVFLFEGVKVVFKVGLALLKYCHDDLVKLPFEK 300
+MYAS WF+T+++ + +L+ RI DVFL EG++ +FKV LALL D L+ L E
Sbjct: 267 QTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLLCLDMEA 326
Query: 301 LIHALRNFPEDAMNPDI--LLPMAFSIKV-SKNLVELKQEYEQQRLKPPE 347
++ + + D+ +A+SIK+ +K + ++++EY+ + K E
Sbjct: 327 MLKFFQKELPGRVEADVEGFFNLAYSIKLNTKRMKKMEKEYQDLKKKEQE 376
Query: CNT0016063
Subject: sp|O60447|EVI5_HUMAN Ecotropic viral integration site 5 proteinPE=1 SV=1
Score = 202 bits (513), Expect = 1e-56, Method: Compositional matrix adjust.
Identities = 108/296 (36%), Positives = 181/296 (61%), Gaps = 9/296 (3%)
Query: 59 GVGGSDWKQYVRRKPHVVKRRIRKGIPDCLRGLVWQLISGSRDLLLLNPGVYEQLVIYET 118
G ++W+++ RRK ++K IRKGIP R +VWQL+ + D+ + N Y +L+ +
Sbjct: 91 GRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQ--YSELLKMSS 148
Query: 119 SASELDIIRDISRTFPSHVFFQQRHGPGQRSLYNVLKAYSVFDRDVGYVQGMGFVAGLLL 178
+L I RDI+RT+P H FF+ + GQ L+NV+KAYS+ DR+VGY QG F+ GLLL
Sbjct: 149 PCEKL-IRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLL 207
Query: 179 LYMSEEDAFWLLVALLKGAVHTPMEGMYLVGLPLVQQYLFQFDHLVKEHMPKLGEHFAQE 238
+ M EE+AF + V L++ + ++ + + ++QF+++++E +P L HF +
Sbjct: 208 MQMPEEEAFCVFVRLMQ---EYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQ 264
Query: 239 MINPSMYASQWFITVFSYSFPFHLALRIWDVFLFEGVKVVFKVGLALLKYCHDDLVKLPF 298
+ SMYAS WF+T+F +FP +A R++D+F++EG+++VF+VGLALL+ +L++L
Sbjct: 265 SFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAELMQLDM 324
Query: 299 EKLIHAL-RNFPED-AMNPDILLPMAFSIKVS-KNLVELKQEYEQQRLKPPESPVK 351
E + R P PD L+ A+ +K + K + L++EY + K E ++
Sbjct: 325 EGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIE 380
Query: CNT0016063
Subject: sp|Q5ZJ17|RBG1L_CHICK Rab GTPase-activating protein 1-likehomolog OS=Homo sapiens GN=EVI5 PE=1 SV=3
Score = 200 bits (508), Expect = 5e-56, Method: Compositional matrix adjust.
Identities = 113/297 (38%), Positives = 183/297 (61%), Gaps = 19/297 (6%)
Query: 63 SDWKQYVRRKPHVVKRRIRKGIPDCLRGLVWQLISGSRDLLLLNPGVYEQLVIYETSASE 122
++W+ ++K VK + KGIP R +VWQL+ ++ + + + Y +L+ TS E
Sbjct: 143 NEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQSMPIKDQ--YSELLKM-TSPCE 199
Query: 123 LDIIRDISRTFPSHVFFQQRHGPGQRSLYNVLKAYSVFDRDVGYVQGMGFVAGLLLLYMS 182
I RDI+RT+P H FF+++ GQ L+NV+KAYS+ DR+VGY QG F+ GLLL+ M
Sbjct: 200 KLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMP 259
Query: 183 EEDAFWLLVALLKG----AVHTPMEGMYLVGLPLVQQYLFQFDHLVKEHMPKLGEHFAQE 238
EE+AF + V L++ + P M +GL ++QF+ +++EH+P+L HF +
Sbjct: 260 EEEAFCVFVKLMQDYRLRELFKP--SMAELGL-----CMYQFECMIQEHLPELFVHFQSQ 312
Query: 239 MINPSMYASQWFITVFSYSFPFHLALRIWDVFLFEGVKVVFKVGLALLKYCHDDLVKLPF 298
+ SMYAS WF+T+F +FP +A RI+D+F+ EG+++VF+VGLALL+ +L++L
Sbjct: 313 SFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDM 372
Query: 299 EKLI-HALRNFPE--DAMNPDILLPMAFSIKV-SKNLVELKQEYEQQRLKPPESPVK 351
E ++ H + P D + PD L+ A+ +K SK + +L++EY + K E V+
Sbjct: 373 EGMLQHFQKVIPHQFDGV-PDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVE 428
Query: CNT0016063
Subject: sp|Q4KMP7|TB10B_HUMAN TBC1 domain family member 10B OS=Homo sapiensOS=Gallus gallus GN=RABGAP1L PE=2 SV=1
Score = 190 bits (482), Expect = 2e-52, Method: Compositional matrix adjust.
Identities = 107/302 (35%), Positives = 169/302 (55%), Gaps = 18/302 (5%)
Query: 48 ERRIRKWRKMIGVGGSDWKQYVRRKPHVVKRRIRKGIPDCLRGLVWQLISGSRDLLLLNP 107
E+ + W +++G W + +P+ + +++G+P+ LR VWQL++G D N
Sbjct: 508 EKILYSWGELLG----RWHNNLVVRPNGLSTLVKRGVPEALRAEVWQLLAGCHD----NE 559
Query: 108 GVYEQ--LVIYETSASELDIIRDISRTFPSHVFFQQRHGPGQRSLYNVLKAYSVFDRDVG 165
+ ++ ++I SA E I RDI RTFP+H +F+ G GQ SLY + KAYSV+D D+G
Sbjct: 560 AMLDKYRILITMDSAQENVITRDIHRTFPAHDYFKDTEGDGQESLYKICKAYSVYDEDIG 619
Query: 166 YVQGMGFVAGLLLLYMSEEDAFWLLVALLKGAVHTPMEGMYLVGLPLVQQYLFQFDHLVK 225
Y QG F+A +LLL+M EE AF + V ++ + +Y + FQ + L++
Sbjct: 620 YCQGQSFLAAVLLLHMPEEQAFCVFVKIM---YDYGLRDLYRNNFEDLHCKFFQLEKLMQ 676
Query: 226 EHMPKLGEHFAQEMINPSMYASQWFITVFSYSFPFHLALRIWDVFLFEGVKVVFKVGLAL 285
E +P L HF+ + MYASQWF+T+F+ FP + I D+ L EG+ ++F V LAL
Sbjct: 677 EQLPDLYSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGMNIIFHVALAL 736
Query: 286 LKYCHDDLVKLPFEKLIHALR-NFPE---DAMNPDILLPMAFSIKV-SKNLVELKQEYEQ 340
LK +DL++ FE + R P+ N L+ A +IKV +K L + ++EY+
Sbjct: 737 LKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEREYQT 796
Query: 341 QR 342
R
Sbjct: 797 MR 798
Query: CNT0016063
Subject: sp|A6H6A9|RBG1L_MOUSE Rab GTPase-activating protein 1-like OS=MusGN=TBC1D10B PE=1 SV=3
Score = 188 bits (478), Expect = 4e-52, Method: Compositional matrix adjust.
Identities = 109/321 (33%), Positives = 171/321 (53%), Gaps = 17/321 (5%)
Query: 18 RVDRFGFVKQEHGPTEGLARSRSAFEYQRDERRIRKWRKMIGVGGSDWKQYVRRKPHVVK 77
+ D++GF+ G ++ S+ +R KW M S+W +++ R+ VK
Sbjct: 303 KTDKYGFL----GGSQYSGSLESSIPVDVARQRELKWLDMF----SNWDKWLSRRFQKVK 354
Query: 78 RRIRKGIPDCLRGLVWQLISGSRDLLLLNPGVYEQLVIYETSASELDII-RDISRTFPSH 136
R RKGIP LR WQ +S S++LL NPG +E+L LD+I +D+ R FP H
Sbjct: 355 LRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFH 414
Query: 137 VFFQQRHGPGQRSLYNVLKAYSVFDRDVGYVQGMGFVAGLLLLYMSEEDAFWLLVALLKG 196
F R G GQ+ LY +LKAY+++ D GY Q VA +LL++M E AFW LV +
Sbjct: 415 EMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDK 474
Query: 197 AVHTPMEGMYLVGLPLVQQYLFQFDHLVKEHMPKLGEHFAQEMINPSMYASQWFITVFSY 256
+ G Y GL +Q F L++ P H ++ I+P +Y ++WF+ +F+
Sbjct: 475 Y----LPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFAR 530
Query: 257 SFPFHLALRIWDVFLFEGVKVVFKVGLALLKYCHDDLVKL----PFEKLIHALRNFPEDA 312
+ P+ LR+WD+F EGVK++F+V L LL++ + KL + + LRN P+
Sbjct: 531 TLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQC 590
Query: 313 MNPDILLPMAFSIKVSKNLVE 333
M D L+ ++ V++ L+E
Sbjct: 591 MQEDFLVHEVTNLPVTEALIE 611