Score = 2311 bits (5990), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 1387/2997 (46%), Positives = 1844/2997 (61%), Gaps = 165/2997 (5%)

Query: 1    MKLKRRRAVEVPPSIKSFINSVTTVPLEDVELPLKDFAWEFDKGDFHHWLDLFNHFDSFF 60
            MKL+RRRA EVP  IKSFINSVT+VPLE +  PL  F WEFDKGDFHHW+DLFN+FD+FF
Sbjct: 1    MKLRRRRASEVPSKIKSFINSVTSVPLELIHEPLACFRWEFDKGDFHHWVDLFNYFDTFF 60

Query: 61   ESYIKSRKDLHLEDNFLDVDPPFPREALLQILRVSKLILENCTNRHF-SSFFEHLSALLA 119
            E +++ RKDLH+E+NF + DPPFP++A+LQ+LRV +++LENCTN+HF SS+ +HLS LLA
Sbjct: 61   EKHVQVRKDLHIEENFEESDPPFPKDAVLQVLRVIRVVLENCTNKHFYSSYEQHLSLLLA 120

Query: 120  STDADIVEASLQTLMAFVDKSVGKSSIRXXXXXXXXXXXXQXXXXXXXXXXLVACSLPSV 179
            STDAD+VEA LQTL AF+ + +GK SIR            Q          L +C+  + 
Sbjct: 121  STDADVVEACLQTLAAFLKRQIGKYSIRDASLNSKLFSLAQGWGGKEEGLGLTSCAAENS 180

Query: 180  SDPVSTEVGSTLHFEFYRAADKSEKSQCLEKENKLEVIHLSNVNSCKEADLEILDRLVKD 239
             D VS ++G TLHFEFY  +D+S      E    L+VIH+ +V+ C E+DLE+L++LV D
Sbjct: 181  CDQVSLQLGRTLHFEFY-PSDESPS----ELPGGLQVIHVPDVSICAESDLELLNKLVID 235

Query: 240  YSVPQXXXXXXXXXXXXXXXXDSLTCRHQYICIRLYAFIVLVQAGHDLEVVSTFLNNEPE 299
            ++VP                  SL  R Q+ CIRLYAF+VLVQA  D E V +F N EPE
Sbjct: 236  HNVPPSLRFALLTRMRFARAFSSLATRQQFTCIRLYAFVVLVQASGDTENVVSFFNGEPE 295

Query: 300  FIDEXXXXXXYEDEIPEKIRILGVLSLVALCQDRPHQPTVLSSVTSGGHRGILPILMQNT 359
            F++E      YED +PEKIRIL +LSLVAL QDR  QPTVL++VTSGGHRG+L  LMQ  
Sbjct: 296  FVNELVTLVSYEDTVPEKIRILCLLSLVALSQDRTRQPTVLTAVTSGGHRGLLSGLMQKA 355

Query: 360  VDSIINGSMKWSIIFAEAXXXXXXXXXXXTPGSLALQEAGFIPTILPLLKDTNTQHLHLV 419
            +DS++  + KWS+ FAEA           + G  A++EAG IPT++PL+KDT+ QHLHLV
Sbjct: 356  IDSVVCITSKWSLAFAEALLSLVTVLVSSSSGCSAMREAGLIPTLVPLIKDTDPQHLHLV 415

Query: 420  SKAVHVIESFLDYHNPSSAVFRDLGGLDDTIARLKLEVSQVEVDSKLIDHSTN-EGNEVE 478
            S AVH++E+F+DY NP++A+FRDLGGLDDTI RLKLEVS+ E D K  + S++  G + E
Sbjct: 416  SAAVHILEAFMDYSNPAAALFRDLGGLDDTIFRLKLEVSRTEDDVKEKNCSSDSNGPDTE 475

Query: 479  SYPPVQDIQPSCSESLILYHRKNLIKVLLRTISLATYVPGSSARVDGSEENVLPPCLCAI 538
              P         SE+LI YHR+ L+K LLR ISL TY PG++  + GSEE++LP CLC I
Sbjct: 476  QLP--------YSEALISYHRRLLLKALLRAISLGTYAPGNT-NLYGSEESLLPECLCII 526

Query: 539  FKRGKDFGGGVFSLAANVMSDLIHKDPTCYTVLDSAGLPQAFLDAIMCGGLYNSDAVSCI 598
            F+R KDFGGGVFSLAA VMSDLIHKDPTC+  LDSAGL   FLDAI    + +++A++CI
Sbjct: 527  FRRAKDFGGGVFSLAATVMSDLIHKDPTCFNALDSAGLTSTFLDAISDEVICSAEAITCI 586

Query: 599  PQCLDALCLNNNGLQLVKDRNALRCFVKIFTSRSYMKALSGDTAGALSSGLDELMRHAPS 658
            PQCLDALCLNN+GLQ VKDRNALRCFVKIFTS SY++AL+GDT G+LSSGLDEL+RH  S
Sbjct: 587  PQCLDALCLNNSGLQAVKDRNALRCFVKIFTSPSYLRALTGDTPGSLSSGLDELLRHQSS 646

Query: 659  LRSSGVSMFIEILNTIFKVWCGVDSIPYKESD--NYSAVIPMDTDVVVATSQSEGVPPEV 716
            LR+ GV MFIEILN++  +  G+++   K +D    +A +PM+ DV     +S  V  E 
Sbjct: 647  LRTYGVDMFIEILNSMLIIGSGMEATTSKSADVPTSAAPVPMEIDV---DEKSLAVSDEA 703

Query: 717  GCSGETVDAPLDAVTSSSIELFLPECICNVARLLETVLQNADICRLFIEKKGIEAVLQLF 776
              S +T        + ++IELFLP+C+CNVARL ETVLQNA++C LF+EKKGI+AVLQLF
Sbjct: 704  EPSSDT--------SPANIELFLPDCVCNVARLFETVLQNAEVCSLFVEKKGIDAVLQLF 755

Query: 777  KLPSIPVSVSIGQSISVAFKNFSPQHSVSLARAVCSFFRDHLKITNELLGSISGTMLVGS 836
             LP +P+S S+GQS SVAFKNFSPQHS  LAR VCS+ R+HLK T  LL SI GT L+  
Sbjct: 756  SLPLMPLSTSLGQSFSVAFKNFSPQHSAGLARIVCSYLREHLKKTKILLVSIEGTQLLKL 815

Query: 837  EPAKQSALLKPLSTLEGLLSIANFLLKGTTIMVSELAFADAEILKELGKVYIEVTWQISL 896
            E A Q+ +L+ LS LEG+LS++NFLLKG+  ++SEL+ ADA++LKELG  Y +  WQ++L
Sbjct: 816  ESAIQTKILRSLSCLEGMLSLSNFLLKGSASVISELSAADADVLKELGITYKQTIWQMAL 875

Query: 897  LSDSKVXXXXXX----XXXXXXXXSISERDSDDDTNTAPLSRYMNPVSARASISP--WSM 950
             +D+K                   S +ER+SD+D++ A   RY NPVS R+S S   W  
Sbjct: 876  CNDTKEDEKKSVDRGSDNSVSASSSTAERESDEDSSNALAVRYTNPVSIRSSSSQSIWGG 935

Query: 951  EQDFVSTVRSVSHMHHHGRHSLSRI-SGRLNGVLNATSTDLDGPCFPAETSRRHDALKRI 1009
            +++F+S VRS   +H   RH+++R+  GR    L + + D + P     TS  H+  K+ 
Sbjct: 936  DREFLSIVRSGEGIHGRTRHAIARMRGGRTRRHLESFNFDSEIPADLPVTSSSHELKKKS 995

Query: 1010 PDDVVSELLKKFCCTMRSFLSTLVKGLPA--HRRPD-SNLNPNSRSLVTALAQFFLSALG 1066
             + +++E+L K  CT+R F + LVKG  +   RR D ++L+  S++L TALA+ FL AL 
Sbjct: 996  TEVLIAEILNKLNCTLRFFFTALVKGFTSANRRRIDGASLSSASKTLGTALAKVFLEALN 1055

Query: 1067 FSGH-STAGFEMSLSVKCRYLGKVVEDMAVLTFDSRRRLCNSALVNSFYVNGTFKDVLTT 1125
            F G+ + AG E SLSVKCRYLGKVV+D+  L+FD+RRR+C +A+VNSFYV+GTFK++LTT
Sbjct: 1056 FDGYGAAAGHEKSLSVKCRYLGKVVDDITFLSFDTRRRVCFTAMVNSFYVHGTFKELLTT 1115

Query: 1126 FEATSQLLWTLPFSVLAAATDQGSSINEKV-SHNSWLLDTLQSYCKFLEYYVNSTFLLSP 1184
            FEATSQLLWT+PFS+ A++T+        + SH+ WL+DTLQ+YC+ L+Y+VNST+LLSP
Sbjct: 1116 FEATSQLLWTVPFSIPASSTENEKPGERNIWSHSKWLVDTLQNYCRALDYFVNSTYLLSP 1175

Query: 1185 SSSHNRLLVQPIVTELSINLFPVPSDPESFARMLQSQVLDAVLPVWNHTMFPVCNPAFVT 1244
            +S   +LLVQP    LSI LFPVP +PE+F R LQSQVLD +LP+WNH MFP CNP FV 
Sbjct: 1176 TS-QTQLLVQPASVGLSIGLFPVPREPETFVRNLQSQVLDVILPIWNHPMFPDCNPNFVA 1234

Query: 1245 SLVSIMNNICSVVGDMKQSRSSV--GVANQRVTGPPLDESAIATIVEMGFSRARAEESLR 1302
            S+ S++ +I S V D +++RS V  G+ NQR     LDES +  IVEMGFSR+RAE +LR
Sbjct: 1235 SVTSLVTHIYSGVVDARENRSGVTRGI-NQRALPLQLDESIVGMIVEMGFSRSRAEIALR 1293

Query: 1303 SVRTNSVEMATDWLFNHPEDSVQEDVXXXXXXXXXXXXXIETPKEDGSNKNDTVIAEEKG 1362
             V TNSVEMA DWLF +PE  VQED               ETPK + + K   V  EE  
Sbjct: 1294 RVGTNSVEMAMDWLFTNPEQPVQEDDELAQALALSLGNSSETPKLEDTEKPVDVPQEEAE 1353

Query: 1363 VFVLPLDDILTVSTKLFQSSDSTLAFPLTDLLATLCNRNKSEYCKRVVLYLFEQLRHFSS 1422
                P+D+++  S KLFQS DS +AFPL DL  TLCNRNK E   ++V YL +QL+    
Sbjct: 1354 PKEPPVDEVIAASVKLFQSDDS-MAFPLMDLFVTLCNRNKGEDRPKIVSYLIQQLKLVQL 1412

Query: 1423 D-ATDMGALYSVAHVLALLLSEDSGIRETSAENGVISQVLNILG--SLKSRTDQTDHTWN 1479
            D + D GAL  + H+LAL+LSED   RE +A++G+++  + IL   +LKS ++       
Sbjct: 1413 DFSKDTGALTMIPHILALVLSEDDNTREIAAQDGIVTVAIGILTDFNLKSESETEILAPK 1472

Query: 1480 SISALLLILYNMLQFNPKLSMETMDGXXXXXXXXXXXXXXXNPLPTAEHRTEII------ 1533
             ISALLL+L  MLQ   KLS E ++G                P  + +  T  +      
Sbjct: 1473 CISALLLVLSMMLQAQTKLSSEYVEGNQGGSLV---------PSDSPQDSTAALKDALSS 1523

Query: 1534 DSADDASANVFKKILGKSTGYLNDQESQKALVFCCEFIKLCVPATVMHAVLQLSARLTKT 1593
            D A   S    + I GKSTGYL  +E  KAL+  C  IK  VPA +M AVLQL ARLTK+
Sbjct: 1524 DVAKGESNQALELIFGKSTGYLTMEEGHKALLIACGLIKQHVPAMIMQAVLQLCARLTKS 1583

Query: 1594 HALAALFFESGGLASLLNLPGTCIFPGFETLASAIVRHLIEDPQTLQSAMELEIRQSLSN 1653
            HALA  F E+GGL+SL NLP  C FPG++T+AS IVRHL+EDPQTLQ AME EIRQ+LS 
Sbjct: 1584 HALAIQFLENGGLSSLFNLPKKCCFPGYDTVASVIVRHLVEDPQTLQIAMETEIRQTLSG 1643

Query: 1654 H---GSRTPSSFLTNMAPLISRDPVIFMKAATSVCQLDYSGGRLNVVLLKDKEKDREKQN 1710
                G   P +FLT MAP+ISRDPV+FMKA  S CQL+ SGGR  V+L K+KEK +    
Sbjct: 1644 KRHIGRVLPRTFLTTMAPVISRDPVVFMKAVASTCQLESSGGRDFVILSKEKEKPK---- 1699

Query: 1711 VPVTESGVPCNEPVRVTAEVKTVDTPNRCSRNHKKVPASLPQVIDQLLEIIMSYPSASKE 1770
            V  +E G   NEP+ ++ E K  D   +CS++H++VPA+  QVIDQL+++++S+P   ++
Sbjct: 1700 VSGSEHGFSLNEPLGIS-ENKLHDVSGKCSKSHRRVPANFIQVIDQLIDLVLSFPRVKRQ 1758

Query: 1771 HGFDGYSLLTPMDVDEPNTK--GKSKVGDGQ--------ELDGDAFSERSALLSKFAFVL 1820
               DG + L  M+VDEP TK  GKSKVG+ +        E +     E+S  L++  F+L
Sbjct: 1759 E--DGETNLISMEVDEPTTKVKGKSKVGEPEKASSSRVGEPEKAEIPEKSEELARVTFIL 1816

Query: 1821 KLMSEILLMYVHAVGIILRRDTEISVSR--SCAQGAGHSGXXXXXXXXXXXXXSVKIADT 1878
            KL+S+I+LMY H   +ILRRDTEIS  R  +    +  +G             S++    
Sbjct: 1817 KLLSDIVLMYSHGTSVILRRDTEISQLRGSNLPDDSPGNGGLIYHVIHRLLPISLEKFVG 1876

Query: 1879 SDDWIGNLSERASWFLVALCCRSAEGRRRVVSEIVKALNQFIGSASNTSRGSLIPDRKVL 1938
             ++W   LSE+ASWFLV LC RS EGR+R+++E+ + L+ F     ++S+  L+PD++VL
Sbjct: 1877 PEEWKEKLSEKASWFLVVLCSRSNEGRKRIINELSRVLSVFASLGRSSSKSVLLPDKRVL 1936

Query: 1939 AFSELVNSILSRNSQS---NLPVLGCSPDIAKPMVDGGMVQSLSVLLKVIDLDHPDAVRV 1995
            AF+ LV SIL++NS S   N P  GCSPD+AK M+DGG +Q L+ +L VIDLDHPDA ++
Sbjct: 1937 AFANLVYSILTKNSSSSSSNFPGCGCSPDVAKSMMDGGTIQCLTSILHVIDLDHPDAPKL 1996

Query: 1996 VNLILKALDSLTRTAYTTDQVLNS-DRFTKNRLPGSHEQTH------EADDIVIPEQTTY 2048
            V LILK+L++LTR A   +Q+ +      KNR       +H      EAD++    Q   
Sbjct: 1997 VTLILKSLETLTRAANAAEQLKSEVPNEKKNRDSDERHDSHGNSTETEADEL---NQNNS 2053

Query: 2049 DSHHHTNDIESASQQAQELSHVGGNNNENLDQPAEQEMGVDLADNSTSNGNPPTRAVQFM 2108
                 T+   +  +QAQ  S   G    +  Q   Q+M ++  D +     P    + FM
Sbjct: 2054 SLQQVTDAAGNGQEQAQVSSQSAGERGSSQTQAMPQDMRIE-GDETIL---PEPIQMDFM 2109

Query: 2109 REEPIEGNVMAPSTDIGLAFSMQHQVDGMGVXXXXXXXXXXXXXXXXXXXXX--XXLMSI 2166
            REE IEG+       I ++F ++++ D                             +MS+
Sbjct: 2110 REE-IEGD------QIEMSFHVENRADDDVDDDMGDEGEDDEGDDEDADLVEDGAGVMSL 2162

Query: 2167 ADTDIEDQENNAIGXXXXXXXXXXXXXXFLENHVIEVRWRESLTRMDYDHHLRFSRGRAD 2226
            A TD+ED E+  +G              F EN VIEVRWRE+L  +D+   L  S G   
Sbjct: 2163 AGTDVEDPEDTGLGDEYNDDMVDEDDDDFHENRVIEVRWREALDGLDHFQILGRSGG--- 2219

Query: 2227 SSGFID-ISSESFHGVGTVDSFNLHRSFGLERRRQIGSRSLLDRPRTDVNAFLHPLLVRP 2285
             +GFID I++E F GV   D F L R  G ERRRQ G RS LDR  ++V+ F HPL  RP
Sbjct: 2220 GNGFIDDITAEPFEGVNVDDLFALRRPLGFERRRQTG-RSSLDRSGSEVHGFQHPLFSRP 2278

Query: 2286 AQSREGTNSAWPSGGTSSRDFHMLSFDIPS-YMLDAGFSPETAPPV--FGERVVST-APP 2341
            +Q+   T S   S G+ SR     S+D+   YM D    P    PV  F  R+    APP
Sbjct: 2279 SQTG-NTASVSASAGSISRHSEAGSYDVAQFYMFDTPVLPFDQVPVDPFSARLAGGGAPP 2337

Query: 2342 PLIDFSL-GMDSLRIRRGPGDNLWTDDGXXXXXXXXXXXXXXVEDHFVSQLTVANNSNSA 2400
            PL D+S+ GMDS   RRG GD+ WTD G              +E+HF+S L  +   N+ 
Sbjct: 2338 PLTDYSVVGMDS--SRRGVGDSRWTDIGHPQPSSLSASIAQLIEEHFISNLRASAPVNTV 2395

Query: 2401 PQVRPEQTGNGANAHSELPDTGNAEPVTTDP---LSQPVGRHQLVCTVNQGPVPANDVLC 2457
             +     T      H ++P +  +E V  D      Q   R  L    N    P  DV+ 
Sbjct: 2396 VERETNTTEIQEQLHPDVPPSVGSETVLGDGNEGGQQSEERELLNNNENVNNPP--DVMA 2453

Query: 2458 PTDVHVNQHLVDSIYDSRVVEPVQQTAAGDP---NTIPQSDEMMCIAGTQLGGHPERDSL 2514
             +      +L   +      E +QQ     P   N+ P   + M +              
Sbjct: 2454 ESFAQGQANLASPVSQD-TGESLQQLEVMQPLPLNSTPNEIDRMEV-------------- 2498

Query: 2515 SGNGSYGNIMQNEIEAPQQVHLGNDPREPPSDLESSCHALVTSASAAPELSDAHVDSSAV 2574
             G G    I Q + EA   VHL +  +  P   ++S    V+  + AP + D   +    
Sbjct: 2499 -GEGDGAPIDQVDHEA---VHLISTAQGQP---DTSSIQNVSVTAIAPPVDDPDSNFQP- 2550

Query: 2575 NADVDMNIVDIAENEVGNSAPA-SDGNDLSSRRYEDALQEPQTVQTNAIN-EASSANEID 2632
            + DVDM+      N+    +P   D N+LSS    + ++  + V+  +++  A   N ID
Sbjct: 2551 SVDVDMSSDGAEGNQSVQPSPLDGDNNELSSMEATENVRNDEQVEEGSLDGRAPEVNAID 2610

Query: 2633 PTFLEALPEDLRAEVLASQQNRXXXXXXXXXXXXEEIDPEFLAALPPDIQAEVLAQQRAQ 2692
            PTFLEALPEDLRAEVLASQQ +            ++IDPEFLAALPPDIQ EVLAQQRAQ
Sbjct: 2611 PTFLEALPEDLRAEVLASQQAQSVQPPTYEPPPVDDIDPEFLAALPPDIQTEVLAQQRAQ 2670

Query: 2693 RIAHSQPAGQPVDMDNASIIATFPPDLREEVLLTXXXXXXXXXXXXXXXXXQMLRDRELS 2752
            R+   Q  GQ VDMDNASIIAT P DLREEVLLT                 QMLRDR +S
Sbjct: 2671 RMVQ-QSQGQAVDMDNASIIATLPADLREEVLLTSSEAVLAALPSPLLAEAQMLRDRAMS 2729

Query: 2753 RYRARGSLFGGSYRLGGRR--LPTDNQTVIDRAVGVTVGRRVISTTCSS-KGKDVEGTPL 2809
             Y+AR S+FG S+RL  RR  L  +  T +DR VGVT+G+R +S++    K K++EG PL
Sbjct: 2730 HYQARSSVFGSSHRLNNRRNGLGYNRLTGMDRGVGVTIGQRAVSSSADGLKVKEIEGDPL 2789

Query: 2810 LDSEXXXXXXXXXXXXXXXSRGLLQRLMSNLCAHSVTRVTLVGHLLNMIKPEYEGLSVSD 2869
            ++++                +GLLQRL+ NLCAHS TR  LV  LL+MI+PE E  S S+
Sbjct: 2790 VNADALKSLIRLLRLAQPLGKGLLQRLLLNLCAHSFTRANLVQLLLDMIRPEME-TSPSE 2848

Query: 2870 CMAT--YRLHGCHWNIVYAQSCSANGVPPLVTRRLLEILTYLASASPSVVDLLIYFN 2924
               T   RL+GC  N+VY +S   NG+PPLV RR+LE+LTYLA+   +V D+L YF+
Sbjct: 2849 LAITNPQRLYGCQSNVVYGRSQLLNGLPPLVFRRVLEVLTYLATNHSAVADMLFYFD 2905



 Score =  960 bits (2482), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 492/675 (72%), Positives = 552/675 (81%), Gaps = 19/675 (2%)

Query: 3048 SCAKLDVNVHAILTQLPDAELHNLCNILALEGLPDKVYSLAAEVVKKLASVAASHRKFFS 3107
            +CA+    ++ I  QLP ++L NLC +L  EGL DK+YSLA EV+KKLA+V  +HRKFF+
Sbjct: 3018 NCAE----IYNIFLQLPQSDLCNLCILLGYEGLSDKIYSLAGEVLKKLAAVDVAHRKFFT 3073

Query: 3108 IELAGVAQSLSSSAVEELVTLKNTQMLGLSTCSMAGAAILRILQVLSTLTSCVMDSR--H 3165
             EL+ +A SLSSS V EL TL + Q +  ST SMAGA+ILR+LQVLS+LTS + +S    
Sbjct: 3074 KELSELASSLSSSTVRELATLSSKQKMSRSTGSMAGASILRVLQVLSSLTSPIDESNVGT 3133

Query: 3166 EQDLGQEEQSFLWDLNAGLQPLWQELSDCISATEAKLVHNSSFASHXXXXXXXXXXXXXX 3225
            E++  QEEQ+ +  LN  L+PLW ELS CIS TE +L H ++ ++               
Sbjct: 3134 ERETEQEEQNIMQRLNVALEPLWHELSQCISMTELQLDHTAAASN----INPGDHVLGIS 3189

Query: 3226 XXXXXXXGTQRLLPFIESFFVLCEKLQTNQPVAQSDYTVIAPEVKESA--GSSSSPSL-- 3281
                   GTQRLLP IE+FFVLCEK+QT   + Q D  V A EVKES+  GSSS  S+  
Sbjct: 3190 PTSSLSPGTQRLLPLIEAFFVLCEKIQTPS-MLQQDTNVTAGEVKESSAHGSSSKTSVDS 3248

Query: 3282 --KTGGTCNVTFIRIAEKHRRLLNVFIRQNPSILEKSLSMMLKVPRLIDFDNKRAYFRSR 3339
              KT G+  VTF + AEKHRRLLN FIRQNPS+LEKSLSMMLK PRLIDFDNK+AYFRSR
Sbjct: 3249 QKKTDGS--VTFSKFAEKHRRLLNSFIRQNPSLLEKSLSMMLKAPRLIDFDNKKAYFRSR 3306

Query: 3340 IRQQHDQHLPAPLHISVRRAYVLDDSYNQLRLRRTQDLKGRLTVQFQGEEGIDAGGLTRE 3399
            IR QHDQH+  PL ISVRRAYVL+DSYNQLR+R  QDLKGRL VQFQGEEGIDAGGLTRE
Sbjct: 3307 IRHQHDQHISGPLRISVRRAYVLEDSYNQLRMRSPQDLKGRLNVQFQGEEGIDAGGLTRE 3366

Query: 3400 WYQLLSRVIFDKGTLLFTTVGNNATFQPNPNSDFQTEHLSYFKFVGRVVAKALFDGQLLD 3459
            WYQLLSRVIFDKG LLFTTVGN+ATFQPNPNS +QTEHLSYFKFVGR+VAKALFDGQLLD
Sbjct: 3367 WYQLLSRVIFDKGALLFTTVGNDATFQPNPNSVYQTEHLSYFKFVGRMVAKALFDGQLLD 3426

Query: 3460 VHFTRSFYKHILGAKVTYHDIEAIDPDYYRNLKWMLENDVSDLPYLTFSMDPDEEKHILY 3519
            V+FTRSFYKHILG KVTYHDIEA+DPDYY+NLKW+LENDVSD+  LTFSMD DEEKHILY
Sbjct: 3427 VYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLLENDVSDILDLTFSMDADEEKHILY 3486

Query: 3520 EKTEVTDYELKPGGRNIRVTEETKQEYVDLVAEHILTTAIRPQINGFLEGFTELVPRDLI 3579
            EKTEVTDYELKPGGRNIRVTEETK EYVDLVA HILT AIRPQIN FLEGF EL+PR+L+
Sbjct: 3487 EKTEVTDYELKPGGRNIRVTEETKHEYVDLVAGHILTNAIRPQINAFLEGFNELIPRELV 3546

Query: 3580 SLFNDKELELLISGLPEIDLDDLKANTEYIGYSAASPVIQWFWEVVRAFSKEDMARLLQF 3639
            S+FNDKELELLISGLPEID DDLKANTEY  Y+A SPVI WFWEVV+AFSKEDMAR LQF
Sbjct: 3547 SIFNDKELELLISGLPEIDFDDLKANTEYTSYTAGSPVIHWFWEVVKAFSKEDMARFLQF 3606

Query: 3640 VTGTSKVPLEGFKALQGISGPQRFQIYKAYGSPGRLPSAHTCFNQLDLPEYTSKEQLEER 3699
            VTGTSKVPLEGFKALQGISGPQR QI+KAYG+P RLPSAHTCFNQLDLPEY SKEQL+ER
Sbjct: 3607 VTGTSKVPLEGFKALQGISGPQRLQIHKAYGAPERLPSAHTCFNQLDLPEYQSKEQLQER 3666

Query: 3700 LLLAIHEASEGFGFG 3714
            LLLAIHEASEGFGF 
Sbjct: 3667 LLLAIHEASEGFGFA 3681

 Score =  502 bits (1292), Expect = e-141,   Method: Compositional matrix adjust.
 Identities = 273/674 (40%), Positives = 399/674 (59%), Gaps = 66/674 (9%)

Query: 3063 LPDAELHNLCNILALEGLPDKVYSLAAEVVKKLASVAASHRKFFSIELAGVAQSLSSSAV 3122
            +P+  L  + NI        K +      +K L+++  + +K F  EL   A+ LS + +
Sbjct: 3447 IPEHNLKLVINIFVARECSSKTFQNTISTIKNLSNIPGA-KKVFGDELVRQARVLSENIL 3505

Query: 3123 EELVTL--------KNTQMLGLSTCSMAGAAIL--RILQVLSTLTSCVMDSRHEQDLGQE 3172
             +L  L          TQ+ G++    +  A    ++L+VL+ L         +QD   E
Sbjct: 3506 SDLDNLLPHILKAESGTQIQGVALAKFSPGASEQNKLLRVLTALDHLFDSKSKKQDKPAE 3565

Query: 3173 EQSFLWDL------NAGLQPLWQELSDCISATEAK--LVHNSSFASHXXXXXXXXXXXXX 3224
             ++   DL      N     +W +LS C+SA   +  +++ ++                 
Sbjct: 3566 GENTKEDLLGSLYWNPTFGKMWDKLSACLSAIRQRDNMLNVATI---------------- 3609

Query: 3225 XXXXXXXXGTQRLLPFIESFFVLCEKLQTNQPVAQSDYTVIAPEVKESAGSSSSPSLKTG 3284
                        LLP IES  V+C+    +   A S+    A   KE   +S  P  +  
Sbjct: 3610 ------------LLPLIESLMVVCKNTTLSDASAVSN----ANSQKEMLLTSPPPEDRIA 3653

Query: 3285 GTCNVTFIRIAEKHRRLLNVFIRQNPSILEKSLSMMLKVPRLIDFDNKRAYFRSRIRQQH 3344
            G     F    E+HRR+LN  +R NP ++  + S+++K P++++FDNKR YF   +  ++
Sbjct: 3654 GL----FFTFTEEHRRILNELVRHNPKLMSGTFSLLVKNPKVLEFDNKRNYFNRSVHSKY 3709

Query: 3345 DQ--HLPAPLHISVRRAYVLDDSYNQLRLRRTQDLK-GRLTVQFQGEEGIDAGGLTREWY 3401
             Q  H   PL + VRR +V  DS+  L  ++  +LK G+L ++FQGEEG+DAGG+TREW+
Sbjct: 3710 QQTRHSFPPLQLQVRREHVFHDSFRSLYYKKADELKFGKLNIRFQGEEGVDAGGVTREWF 3769

Query: 3402 QLLSRVIFDKGTLLFTTVGNN-ATFQPNPNSDFQTEHLSYFKFVGRVVAKALFDGQLLDV 3460
            Q+LSR +FD   +LF  V ++  TF PN  S    EHL +FKF+GR++ KAL++G+LL+ 
Sbjct: 3770 QVLSRQMFDPNYVLFVPVSSDRTTFHPNKLSPINDEHLPFFKFIGRIIGKALYEGRLLEC 3829

Query: 3461 HFTRSFYKHILGAKVTYHDIEAIDPDYYRNLKWMLENDVSDLPYLTFSMDPDEEKHILYE 3520
            +F+R+ YK ILG  V+  D+E+ DPDYY++L WMLEND++D+   TFS++ D     ++ 
Sbjct: 3830 YFSRAVYKRILGKPVSVKDMESFDPDYYKSLVWMLENDITDIITETFSVEDD-----VFG 3884

Query: 3521 KTEVTDYELKPGGRNIRVTEETKQEYVDLVAEHILTTAIRPQINGFLEGFTELVPRDLIS 3580
            + +V D  L   GRNI VTEE K EYV L+ EH L T+++ Q+  FL GF E++P +LI+
Sbjct: 3885 EVKVVD--LIENGRNIPVTEENKHEYVRLIVEHKLITSVKDQMKAFLTGFHEIIPEELIA 3942

Query: 3581 LFNDKELELLISGLPEIDLDDLKANTEYIGYSAASPVIQWFWEVVRAFSKEDMARLLQFV 3640
            +FN++ELELLISGLP+ID+DD KANTEY  YSA +P IQWFW  VR+F KE++A+LLQFV
Sbjct: 3943 IFNEQELELLISGLPDIDIDDWKANTEYHNYSAGAPQIQWFWRAVRSFDKEELAKLLQFV 4002

Query: 3641 TGTSKVPLEGFKALQGISGPQRFQIYKAYGSPGRLPSAHTCFNQLDLPEYTSKEQLEERL 3700
            TGTSKVPL GFK L+G++G  RF I++ YGS  RLPS+HTCFNQLDLPEY + E L  +L
Sbjct: 4003 TGTSKVPLNGFKELEGMNGVSRFNIHRDYGSKDRLPSSHTCFNQLDLPEYENYETLRSQL 4062

Query: 3701 LLAIHEASEGFGFG 3714
            L AI   S+ FGF 
Sbjct: 4063 LKAITAGSDYFGFA 4076



 Score = 66.6 bits (161), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 46/104 (44%), Positives = 58/104 (55%), Gaps = 9/104 (8%)

Query: 2631 IDPTFLEALPEDLRAEVLA---SQQNRXXXXXXXXXXXXEEIDPEFLAALPPDIQAEVLA 2687
            ID  +LEALPE+ R EV+A   S +               E+  EFL ALP +++ E+L 
Sbjct: 2976 IDAEYLEALPEEFRDEVIAQAISTRRSQAREQVSQEGENTEVFQEFLEALPEELRNEILH 3035

Query: 2688 Q-QRAQRIAHSQPA--GQ---PVDMDNASIIATFPPDLREEVLL 2725
            Q Q  QR    Q A  GQ   P DMD ASI+ TFPP LR++VLL
Sbjct: 3036 QEQHEQRRRERQNAAGGQDLGPADMDPASILLTFPPGLRQQVLL 3079



 Score = 60.1 bits (144), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 29/99 (29%), Positives = 62/99 (62%), Gaps = 2/99 (2%)

Query: 587 GGLYNSDAVSCIPQCLDALCLNNNGLQLVKDRNALRCFVKIFTSRSYMKALSGDT--AGA 644
           G L +S++++ IP  L+++ LNN G+++V    A++ +++IF S ++++ ++ D   A  
Sbjct: 815 GILPSSESMNIIPTVLNSISLNNRGMKMVLSSGAIQSYMEIFESATHVQCMAHDPELAST 874

Query: 645 LSSGLDELMRHAPSLRSSGVSMFIEILNTIFKVWCGVDS 683
           + S LDEL RH P+LR +  +  I+++  +  +   +D+
Sbjct: 875 IGSSLDELSRHHPALRPAIANAIIDMIARVTHLVKTMDA 913

 Score =  474 bits (1221), Expect = e-133,   Method: Compositional matrix adjust.
 Identities = 249/578 (43%), Positives = 354/578 (61%), Gaps = 63/578 (10%)

Query: 3144 AAILRILQVLSTLTSCVMDSR---HEQDLGQEEQSFLWDLNAGLQPLWQELSDCISATE- 3199
            A +LR L+ L      + + R    EQ  G   Q   +  N     LW+ LS+C+SA   
Sbjct: 2706 AKLLRCLKALDY----IFERRPKGQEQSPGNIIQLLEFYDNLKFSSLWEVLSECLSALRD 2761

Query: 3200 -AKLVHNSSFASHXXXXXXXXXXXXXXXXXXXXXGTQRLLPFIESFFVLCEKLQTNQPVA 3258
               + H S+                             LLP IES  V+C          
Sbjct: 2762 HTSITHVSTV----------------------------LLPLIESLMVICR--------- 2784

Query: 3259 QSDYTVIAPEVKESAGSSSSPSLKTGGTCNVTFIRIAEKHRRLLNVFIRQNPSILEKSLS 3318
                 ++  E+ E  G   SP L+   T    FI   E+HR+++N+ +   PS++  S S
Sbjct: 2785 -----LVFIELPEDVGKHISPILERFKTL---FISFTEEHRKIINMMVFTTPSLMSGSFS 2836

Query: 3319 MMLKVPRLIDFDNKRAYFRSRIRQQHDQHLPAPLHISVRRAYVLDDSYNQLRLRRTQDLK 3378
            +++K P++++F+NKR YF  ++ ++  +    PL+I+VRR +V  DSY  L  +   ++K
Sbjct: 2837 LLVKNPKVLEFENKRNYFNRQLHEEAAKEQYPPLNITVRRDHVFLDSYRALHFKDADEVK 2896

Query: 3379 -GRLTVQFQGEEGIDAGGLTREWYQLLSRVIFDKGTLLFTTV-GNNATFQPNPNSDFQTE 3436
              +L + F+ EEG+DAGG+TREW Q+L+R +F+    LF  V G+  TF PN +S    +
Sbjct: 2897 FSKLNIHFRDEEGVDAGGVTREWLQVLARQMFNPDYALFLPVTGDATTFHPNRDSSVNPD 2956

Query: 3437 HLSYFKFVGRVVAKALFDGQLLDVHFTRSFYKHILGAKVTYHDIEAIDPDYYRNLKWMLE 3496
            HLS+FKF GR++ KAL+DG+LLD HF+R+ YKH+L   V+  DIE++DPDYY++L WML 
Sbjct: 2957 HLSFFKFTGRIIGKALYDGRLLDCHFSRAVYKHMLHRSVSVKDIESLDPDYYKSLVWMLN 3016

Query: 3497 NDVSDLPYLTFSMDPDEEKHILYEKTEVTDYELKPGGRNIRVTEETKQEYVDLVAEHILT 3556
            ND++D+    F++    EK +  EKT V   +L P GRNI VTE  KQ YV+ + ++ L 
Sbjct: 3017 NDITDIITEEFAV----EKDVFGEKTVV---DLIPNGRNIPVTELNKQNYVNRMVDYKLR 3069

Query: 3557 TAIRPQINGFLEGFTELVPRDLISLFNDKELELLISGLPEIDLDDLKANTEYIGYSAASP 3616
             +++ Q+   L+GF++++P  LI +FN++ELELLISGLPEID+DD K NTEY GY+ +SP
Sbjct: 3070 ESVKDQLKSLLDGFSDIIPSHLIQIFNEQELELLISGLPEIDIDDWKNNTEYHGYNVSSP 3129

Query: 3617 VIQWFWEVVRAFSKEDMARLLQFVTGTSKVPLEGFKALQGISGPQRFQIYKAYGSPGRLP 3676
             +QWFW  VR+F +E+ A+LLQF TGTSKVPL GFK L+G+SG QRF I+K+YGS  RLP
Sbjct: 3130 QVQWFWRAVRSFDEEERAKLLQFATGTSKVPLNGFKELEGMSGFQRFNIHKSYGSLNRLP 3189

Query: 3677 SAHTCFNQLDLPEYTSKEQLEERLLLAIHEASEGFGFG 3714
             +HTCFNQLDLPEY + EQL   LL AI+E SEGFGF 
Sbjct: 3190 QSHTCFNQLDLPEYDTYEQLRSMLLTAINEGSEGFGFA 3227



 Score =  148 bits (374), Expect = 9e-34,   Method: Compositional matrix adjust.
 Identities = 165/711 (23%), Positives = 297/711 (41%), Gaps = 51/711 (7%)

Query: 12  PPSIKSFI----NSVTTVPLEDVEL--PLKDFAWEFDKGDFHHWLDLFNHFDSFFESYIK 65
           PP +  FI    N   T  L  V L    +   W + +GD + W+ + N FD+  E  ++
Sbjct: 16  PPRVAEFIRQAQNEEVTSDLGLVSLCSEFRKNDWPYPRGDLYSWVPVLNRFDAILERIVE 75

Query: 66  --SRKDLHLEDNFLDVDPPFPREALLQILRVSKLILENCTNRHFSSFFEHLSALLASTDA 123
             S KD  ++    D D       LL+IL  S  +L +C NR   +   +L  LL S+  
Sbjct: 76  HYSLKD-KVQTKPFDSDT---LSILLEILSFSAHLLSHCANRSIYNSTVYLEYLLNSSVL 131

Query: 124 DIVEASLQTLMAFVDKSV----GK-----SSIRXXXXXXXXXXXXQXXXXXXXXXXLVAC 174
           ++++++L  L+  V K+     GK     S  R                       L+  
Sbjct: 132 EVIDSTLALLLHIVQKATISKRGKQLFSLSQDRLFRFLMFLPQDAMKTGFSQNYETLL-- 189

Query: 175 SLPSVSDPVSTEVGSTLHFEFYRAADKSEKSQCLEKENK-LEVIHLSNVNSCKEADLEIL 233
                S+ +  E  S L   +Y+++   + S   +  ++   ++ L       +   E+L
Sbjct: 190 ----FSNEIPQEWCS-LELSYYKSSPSKDFSSASQPNSEGFSILKLPYNKVLGKPIEELL 244

Query: 234 DRLVKDYSVPQXXXXXXXXXXXXXXXXDSLTCRHQYICIRLYAFIVLVQAGHDLEVVSTF 293
            + + D  +P+                  +  R   I I L A   LV A H   V + F
Sbjct: 245 VKTLHDNQIPEQYSFDLLVSLMLRQNLYDINRRRLMIRIGLLALSNLVYA-HSQAVQTRF 303

Query: 294 LNNEPEFIDEXXXXXXYEDEIPEKIRILGVLSLVALCQDRPHQPTVLSSVTSGGHRGILP 353
           L  +PE           + ++P+  + +      A    +   P+VL+S+      G++ 
Sbjct: 304 LIADPEITTHLANLVSPDVDLPQNFKAVCFECFKAFFFKKSMIPSVLASLNVSVSYGLMM 363

Query: 354 ILMQNTVDSIINGSMKWSIIFAEAXXXXXXXXXXXTPGSLALQEAGFIPTILPLLKDTNT 413
            L+++   ++ N +  +   + ++             G      AG    +   L     
Sbjct: 364 NLVRDFSKNLENPNFYYEREYVDSFYDFLQFMTSSPLGGNMACSAGLTSLLGYHLSVKTP 423

Query: 414 QHLHLVSKAVHVIESFLDYHNPSSAVFRDLGGLDDTIARLKLEVSQVEVDSKLIDHSTNE 473
           Q  ++V++++ +++  +D ++ +   F +  GLD  + R+     Q E+++ L D  + +
Sbjct: 424 QATYVVARSIVMLDHLIDGYSMAFPDFSESKGLDMLVDRV-----QYELEAGLQDIKSGK 478

Query: 474 GNEVESYPPV---QDIQPSCSESLILYHRKNLIKVLLRTISLATYVPGSSARVDGSEENV 530
           GN     P +    D   S     +L   KNL+K +L  I     V      +D S    
Sbjct: 479 GN-----PEIVLNMDYAISYDRYFLL---KNLLKFVLHLIQSGGSVVELRNLIDSS---- 526

Query: 531 LPPCLCAIFKRGKDFGGGVFSLAANVMSDLIHKDPTCYTVLDSAGLPQAFLDAIMCGGLY 590
           L   L  + +  + +G  +F+   N+MS  IH +PTCY ++    L  AFLDA+    L 
Sbjct: 527 LISSLAFLLEHHEVYGSNLFASTTNIMSTFIHNEPTCYGIIHEKKLSHAFLDAVNRKILN 586

Query: 591 NSDAVSCIPQCLDALCLNNNGLQLVKDRNALRCFVKIFTSRSYMKAL-SGDTAGALSSGL 649
           +SDA++ IP    A+CLN+ G  L  ++N +     IFTS ++ K+L S D A  L + +
Sbjct: 587 SSDAITSIPLAFGAICLNSQGFDLFLEKNPIPQLFSIFTSLNHCKSLISSDNAAILGTYI 646

Query: 650 DELMRHAPSLRSSGVSMFIEILNTIFKVWCGVDSIPYKESDNYSAVIPMDT 700
           DELMRH PSL+   V M  +  + +  +    +   Y  +  Y  ++ ++T
Sbjct: 647 DELMRHQPSLKDPIVKMIFKACDQVSALLDNFNPFQYINAKEYPYLLYLET 697

 Score =  443 bits (1140), Expect = e-123,   Method: Compositional matrix adjust.
 Identities = 223/427 (52%), Positives = 296/427 (69%), Gaps = 10/427 (2%)

Query: 3291 FIRIAEKHRRLLNVFIRQNPSIL-EKSLSMMLKVPRLIDFDNKRAYFRSRIRQQHDQHLP 3349
            F+R AE HR +LN  +RQ+ + L +   ++++   R++DFD KR YFR  + +  +    
Sbjct: 3958 FLRFAETHRTVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRK 4017

Query: 3350 APLHISVRRAYVLDDSYNQLRLRRTQDLKGRLTVQFQGEEGIDAGGLTREWYQLLSRVIF 3409
              + + VRR +V +DSY +L  +  +++K RL + F+GEEG DAGGL REWY ++SR +F
Sbjct: 4018 EDMAVHVRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMF 4077

Query: 3410 DKGTLLF-TTVGNNATFQPNPNSDFQTEHLSYFKFVGRVVAKALFDGQLLDVHFTRSFYK 3468
            +    LF T+ G+  T+  NP+S     HLSYFKFVGR+VAKA++D +LL+ +FTRSFYK
Sbjct: 4078 NPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYK 4137

Query: 3469 HILGAKVTYHDIEAIDPDYYRNLKWMLENDVSDLPY-LTFSMDPDEEKHILYEKTEVTDY 3527
            HILG  V Y D+E+ D  +Y+ L ++LENDVS L Y LTFS +  E     +   EV D 
Sbjct: 4138 HILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQE-----FGVCEVRD- 4191

Query: 3528 ELKPGGRNIRVTEETKQEYVDLVAEHILTTAIRPQINGFLEGFTELVPRDLISLFNDKEL 3587
             LKP G NI VTEE K+EYV LV +  +T AIR Q+  FLEGF E++P+ LIS+F ++EL
Sbjct: 4192 -LKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQEL 4250

Query: 3588 ELLISGLPEIDLDDLKANTEYIGYSAASPVIQWFWEVVRAFSKEDMARLLQFVTGTSKVP 3647
            ELLISGLP ID+DDLK+NTEY  Y + S  IQWFW  +R+F + D A+ LQFVTGTSKVP
Sbjct: 4251 ELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 4310

Query: 3648 LEGFKALQGISGPQRFQIYKAYGSPGRLPSAHTCFNQLDLPEYTSKEQLEERLLLAIHEA 3707
            L+GF AL+G++G Q+FQI++   S  RLPSAHTCFNQLDLP Y S E+L   LLLAI E 
Sbjct: 4311 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 4370

Query: 3708 SEGFGFG 3714
            SEGFG  
Sbjct: 4371 SEGFGLA 4377



 Score =  190 bits (483), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 199/833 (23%), Positives = 344/833 (41%), Gaps = 82/833 (9%)

Query: 5   RRRAVEVPPSIKSFINSVTTVPLEDVELPLKDF-AWEFDKGDFHHWLDLFNHFDSFFESY 63
           ++   E P   ++ I+ +     E + L L+    W   K + +HW+DL + FD      
Sbjct: 9   KKTPTEAPADCRALIDKLKVCNDEQLLLELQQIKTWNIGKCELYHWVDLLDRFDGILADA 68

Query: 64  IKSRKDLHLEDNFLDVDPPFPREA---LLQILRVSKLILENCTNRHFSSFFEHLSALLAS 120
            ++ +++      L  D P   +    LL +L  + L++E   +RH  S  EHL+ LLAS
Sbjct: 69  GQTVENMSW---MLVCDRPEKEQLKMLLLAVLNFTALLIEYSFSRHLYSSIEHLTTLLAS 125

Query: 121 TDADIVEASLQTLMAFVDKS---VGKSSIRXXXXXXXXXXXXQXXXXXXXXXXLVAC--S 175
           +D  +V A L  L  F  +S       S +            +          L  C   
Sbjct: 126 SDMQVVLAVLNLLYVFSKRSNYITRLGSDKRTPLLTRLQHLAESWGGKENGFGLAECCRD 185

Query: 176 LPSVSDPVSTEVGSTLHFEFYRAADKSEKSQCLEKENKLEVIHLSNVNSCKEADLEILDR 235
           L  +  P S    +TLHFEFY       K +     N L  IH+  ++   E+  EI++ 
Sbjct: 186 LQMLKYPPS---ATTLHFEFYADPGAEVKIEKRTTSNTLHYIHIEQLDKISESPSEIMES 242

Query: 236 LVKDYSVPQXXXXXXXXXXXXXXXXDSLTCRHQYICIRLYAFIVLVQAGHDLEVVSTFLN 295
           L K YS+P+                 +   R Q +  RL+A  +LV +    E  ++ L 
Sbjct: 243 LTKMYSIPKDKQMLLFTHIRLAHGFSNHRKRLQAVQARLHAISILVYSNALQESANSILY 302

Query: 296 NEPEFIDEXXXXXXYEDEIPEKIRILGVLSLVALC--QDRPHQPTVLSSVTSGGHRGILP 353
           N    I+E        D+   +I+   + +L ++   +  P   +++    +  + G LP
Sbjct: 303 N--GLIEELVDVLQITDKQLMEIKAASLRTLTSIVHLERTPKLSSIIDCTGTASYHGFLP 360

Query: 354 ILMQNTVDSIINGSMK-WSIIFAEAXXXXXXXXXXXTPGSLALQEAGFIPTILPLLK--D 410
           +L++N + ++I+ SM  +   FA A             G  AL   G +  +L ++K   
Sbjct: 361 VLVRNCIQAMIDPSMDPYPHQFATALFSFLYHLASYDAGGEALVSCGMMEALLKVIKFLG 420

Query: 411 TNTQHLHLVSKAVHVIESFLDYHNPSSAVFRDLGGLDDTIARLKLEVSQVEVDSKLI--- 467
                +  V++AV V++      N   A F+   GL   I RL+ EV     +   +   
Sbjct: 421 DEQDQITFVTRAVRVVDLIT---NLDMAAFQSHSGLSIFIYRLEHEVDLCRKECPFVIKP 477

Query: 468 ----DHSTNEGNEVESYPPVQDIQPSCSESLILYHRKNLIKVLLRTISLATYVPGSSARV 523
                 +T EG E+E+   +  +Q     + +L   K+++  L + I    +  G    +
Sbjct: 478 KIQRPSTTQEGEEMET--DMDGVQCIPQRAALL---KSMLNFLKKAIQDPAFSDGIRHVM 532

Query: 524 DGSEENVLPPCLCAIFKRGKDFGGGVFSLAANVMSDLIHKDPTCYTVLDSAGLPQAFLDA 583
           DGS    LP  L  I    + +G  +F LA  V++  + ++P+  + L   GL    L A
Sbjct: 533 DGS----LPTSLKHIISNAEYYGPSLFLLATEVVTVFVFQEPSLLSSLQDNGLTDVMLHA 588

Query: 584 IMCGGL-YNSDAVSCIPQCLDALCLNNNGLQLVKDRNALRCFVKIFTSRSYMKALS---- 638
           ++   +    + +  +P    ALCLN  GLQ            K+  S  Y+ A+     
Sbjct: 589 LLIKDVPATREVLGSLPNVFSALCLNARGLQSFVQCQPFERLFKVLLSPDYLPAMRRRRS 648

Query: 639 ----GDTAGALSSGLDELMRHAPSLRSSGVSMFIEILNTIF------KVWCGVDSIPYKE 688
               GDTA  L S +DELMRH P+L++   +  I++L  I       K  C   SI  ++
Sbjct: 649 SDPLGDTASNLGSAVDELMRHQPTLKTDATTAIIKLLEEICNLGRDPKYICQKPSI--QK 706

Query: 689 SDNYSAVIPMDTD-------------VVVATSQSEGVPPEVGCSGETVDAPLDAV--TSS 733
           +D  +   P  ++               V   QS         + +    P   V  T  
Sbjct: 707 ADGTATAPPPRSNHAAEEASSEDEEEEEVQAMQS------FNSAQQNETEPNQQVVGTEE 760

Query: 734 SIELFLPECICNVARLLETVLQNA---DICRLFIEKKGIEAVLQLFKLPSIPV 783
            I + L + I NV + +E++L N    D C+ F+ +KG+  ++ +  LP++P+
Sbjct: 761 RIPIPLMDYILNVMKFVESILSNNTTDDHCQEFVNQKGLLPLVTILGLPNLPI 813



 Score = 75.1 bits (183), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 56/149 (37%), Positives = 67/149 (44%), Gaps = 15/149 (10%)

Query: 2631 IDPTFLEALPEDLRAEVLASQ-----------QNRXXXXXXXXXXXXEEIDPEFLAALPP 2679
            +DP+FL ALP+D+R EVL +Q            +              E+ PEFLAALPP
Sbjct: 2968 VDPSFLAALPDDIRREVLQNQLGIRPPTRSAPSSNSSAPAVVGNPGVTEVSPEFLAALPP 3027

Query: 2680 DIQAEVLAQQRA--QRIAHSQPAGQPVDMDNASIIATFPPDLREEVLLTXXXXXXXXXXX 2737
             IQ EVLAQQRA  QR   +Q A     MD  + I T P DLR  VL             
Sbjct: 3028 AIQEEVLAQQRAEQQRRELAQNASSDTPMDPVTFIQTLPSDLRRSVLEDMEDSVLAVMPP 3087

Query: 2738 XXXXXXQMLRDRELSRYRA--RGSLFGGS 2764
                  Q LR  + +R R      LFG S
Sbjct: 3088 DIAAEAQALRREQEARQRQLMHERLFGHS 3116



 Score = 70.1 bits (170), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 113/515 (21%), Positives = 201/515 (39%), Gaps = 94/515 (18%)

Query: 1567 CCEFIKLCVPATVMHAVLQLSARLTKTHALAALFFESGGLASLLNLPGTCIFPGFETLAS 1626
            C   + + V    +HA L+L  RLT+ H  A +F E      +LNL  +  F GF  L +
Sbjct: 1762 CVSMLGVPVDPDTLHATLRLCLRLTRDHKYAMMFAELKSTRMILNLTQSSGFNGFTPLVT 1821

Query: 1627 AIVRHLIEDPQTLQSAMELEIRQSLSNH-------------GSRTPSSFLTNMAPLISRD 1673
             ++RH+IEDP TL+  ME  +R + ++              GSR  +  L  + P   R+
Sbjct: 1822 LLLRHIIEDPCTLRHTMEKVVRSAATSGAGSTTSGVVSGSLGSREINYILRVLGPAACRN 1881

Query: 1674 PVIFMKAATSVCQLDYSGGRLNVVLLKDK-EKDREK--------QNVPVTESGVPCNEPV 1724
            P IF + A    ++     R +     D+ E  R K        +  P+  S +P     
Sbjct: 1882 PDIFTEVANCCIRIALPAPRGSGTASDDEFENLRIKGPNAVQLVKTTPLKPSSLPV---- 1937

Query: 1725 RVTAEVKTV-----------DTPNRCSRNHKKVPASLPQVIDQLLE-----IIMSYPSAS 1768
             +   +K V             P    ++  K P    Q + QLL+     +   Y S +
Sbjct: 1938 -IPDTIKEVIYDMLNALAAYHAPEEADKSDPK-PGGTTQEVGQLLQDMGDDVYQQYRSLT 1995

Query: 1769 KEHG-FD---GYSLLT--------PMDV-------------DEPNTKGKSKVGDGQELDG 1803
            ++   FD   G+SL +        P +              +E     K K GD    +G
Sbjct: 1996 RQSSDFDTQSGFSLNSQVFAADGAPAETSTTGTSQGEASTPEETREGKKDKEGDRTSEEG 2055

Query: 1804 DAFSERSALLSKFAFVLKLMSEILLMYVHAVGIILRRDTEISVSRSCAQGAGHSGXXXXX 1863
               S+ S  L   + +L+L++E++  YV    +I      +          G S      
Sbjct: 2056 KQKSKGSKPLMPTSTILRLLAELVRSYVGIATLIANYSYTV----------GQSELIKED 2105

Query: 1864 XXXXXXXXSVKIADTSDDWIGNLSERASWFLVALCCRSA--EGRRRVVSEIVKALNQFIG 1921
                       +  T +    +    A  FL +L    +  + +  +V+E+  AL + + 
Sbjct: 2106 CSVLAFVLDHLLPHTQNAEDKDTPALARLFLASLAAAGSGTDAQVALVNEVKAALGRALA 2165

Query: 1922 SASNTSRGSLIPDRKVLAFSELVNSIL-SRNSQSNLPVLGCSP-------DIAKPMVDGG 1973
             A +T + +     ++ A   ++++I+ S  S S+      +        +I +  +  G
Sbjct: 2166 MAESTEKHA-----RLQAVMCIISTIMESCPSTSSFYSSATAKTQHNGMNNIIRLFLKKG 2220

Query: 1974 MVQSLSVLLKVIDLDHPDAVRVVNLILKALDSLTR 2008
            +V  L+ +   +DL  P+    VN  LK L++L+R
Sbjct: 2221 LVNDLARVPHSLDLSSPNMANTVNAALKPLETLSR 2255