Query: CNT0002160
Subject: sp|P50851|LRBA_HUMAN Lipopolysaccharide-responsive and beige-likeOS=Dictyostelium discoideum GN=lvsC PE=3 SV=2
Score = 636 bits (1640), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 333/737 (45%), Positives = 463/737 (62%), Gaps = 53/737 (7%)
Query: 2100 RRWSVAKIKAVHWTRYLLRYTAIEIFFSDSVAPVFLNFASQKDAKDIGNLIVTTRNEYSF 2159
+RW IK VH RYLLR +AIEIF D +F NF + K + N I + + E+S
Sbjct: 1769 KRWPNEMIKDVHLRRYLLRGSAIEIFMRDKTNYLF-NFKKNERNK-VYNKINSVKREFS- 1825
Query: 2160 PKGSGRDKSGSISFVDRRVAQEMAETARESWRRRDITNFEYLMILNTLAGRSYNDLTQYP 2219
K ++S +M + A W+ R I+NF+YLM LNT+AGR+YNDLTQYP
Sbjct: 1826 -------KEPTLS------PSDMLKKATSEWQARRISNFDYLMTLNTIAGRTYNDLTQYP 1872
Query: 2220 VFPWVLADHSSEVLDFNKSSTFRDLSKPVGALDTKRFEVFEDRYRNFCDPDIPSFYYGSH 2279
VFPWV+AD++S VLD NK+ TFRDLSKP+GAL+ KR E+F+DRY +F DP IP FYYGSH
Sbjct: 1873 VFPWVIADYTSPVLDLNKAETFRDLSKPIGALNEKRLEIFKDRYESFDDPVIPKFYYGSH 1932
Query: 2280 YSSMGIVLYYLLRLEPFTSLHRNLQGGKFDHADRLFQGVEGTYRNCLTNTSDVKELIPEF 2339
YSS GIVL+YL+RLEPFT+ NLQGG+FDH DR+F + + N LT+++DVKELIPEF
Sbjct: 1933 YSSAGIVLFYLIRLEPFTTQFLNLQGGRFDHPDRMFDSIALAWDNSLTSSTDVKELIPEF 1992
Query: 2340 FYMPEFLVNSNSYHLGVKQDGEPIGDVCLPPWAKGSPEEFIRRNREALESEYVSSNLHHW 2399
+YMPEFL N N + G+KQ+G I DV LPPWA SP +FIR NREALES+YVSS+LH W
Sbjct: 1993 YYMPEFLTNHNHINFGIKQNGIGIEDVLLPPWA-SSPSDFIRINREALESDYVSSHLHEW 2051
Query: 2400 IDLVFGYKQRGKPAVEAANIFYYLTYEGAVDLETTEDDLQRAAIEDQIANFGQTPIQIFR 2459
IDL+FG KQRGK A E N+FYYLTYEG+VD+++ ED+ R A E QI NFGQTP Q+F
Sbjct: 2052 IDLIFGIKQRGKQAKEVFNVFYYLTYEGSVDIDSIEDETTRRATESQINNFGQTPTQLFS 2111
Query: 2460 KKHPRRGPPIPIAHPLYFAPDSISLSSIVCNTSQYSSAMLYVGLMDSN----------IV 2509
KKH + P+ +H L + + + ++YV + + N +
Sbjct: 2112 KKHHIQRDPLNESHISILKTPPNQLQAYFLKITN-KNPIVYVYIPEPNPIMSYLVADKVT 2170
Query: 2510 LVDEGLNLSVKMWLTTQLQSGGNFTFSGSQDPF-FGVGSDILSPRKIGIPVPENVELGAQ 2568
++D+ + W + T + PF F + + R+IG+P +V +
Sbjct: 2171 VIDKSRTTTNHKWFPS--------TPNDKISPFTFELDPSSTTKRRIGLPFANDVTISPN 2222
Query: 2569 CFATMQTPSENFLISCGNWENSFQVISLSDGRMVQSIRQHKDVVSCVAVTSDGSILATGS 2628
CFA T ++ISC +W+NSF++ + +++QS+ +HKD V+C+++ SDG L TGS
Sbjct: 2223 CFAI--TSDGRYVISCAHWDNSFKLSFVDSAKLIQSVVKHKDTVTCLSLASDGQTLITGS 2280
Query: 2629 YDTTVMVWEVFRGKTAEKRIRNSQSELPRKNYVIIETPCHILCGHDDIITCLYVNHELDI 2688
DTTVMVW + ++S P+ N + P HIL GHDD ITC+ VN LDI
Sbjct: 2281 KDTTVMVWRI---------ATTNKSGAPKFN----DVPDHILYGHDDEITCVDVNVGLDI 2327
Query: 2689 IISGSKDGTCVFHTLREGRYVRSLRHPSGSPITKLVVSQRGQIVIYADDDLSLHLYSING 2748
ISGSKDGTC+ H L+ G YVRS+ P SPI+ + +S +G IVIY+ DL ++LYSING
Sbjct: 2328 SISGSKDGTCIIHNLKHGEYVRSIYLPRQSPISLIAISNQGYIVIYSQADLMIYLYSING 2387
Query: 2749 KYVAASESNGRLNAVQLSRCGEFLVGAGDQGQIVVRSMNTLEVVKKYQGVGKVLTSLAVT 2808
+ +++ RL+++ +S+ E+L+ G++G +V+R++ L+ G + SLA+
Sbjct: 2388 GLLKTVDTHERLHSIIISKDSEYLITGGERGVVVIRTLFNLKPTNHKLVFGTPIHSLAMA 2447
Query: 2809 PEECFL-AGTKDGSLLV 2824
++ L G +DG LL+
Sbjct: 2448 SDQKHLMVGLEDGRLLI 2464
Score = 302 bits (774), Expect = 8e-81, Method: Compositional matrix adjust.
Identities = 237/838 (28%), Positives = 413/838 (49%), Gaps = 83/838 (9%)
Query: 442 LLVGMRDMLQANQAYYQTLFRDGECFLHVVSLLNSNLDEANGEKLVLNVLQTLTCLLASN 501
+L G+R +++ N Q LF+ F+ +V+L+N++ + L +VL+T+ L+A+N
Sbjct: 1 MLDGIRQIIK-NNPKKQNLFKKFRVFIKIVNLVNADDKKERLSVLCHSVLRTVILLMANN 59
Query: 502 DTSKAAFRTLAGKGYQTLQSLLLDFCQWHSSESLLDALLDMLVDGKFNVKMSPMIKNEDV 561
K FR G Y T++ L++ + SE+ ++ L DM+VDG+F+++ +I+N D
Sbjct: 60 PKIKKHFRNHIG--YDTIKDLIIK-SEGIVSETTMNILFDMIVDGEFDIEYKYVIQNPDS 116
Query: 562 IILYLIVLQKSSESLQHHGLDIFQQLLRDSISNRASCVRAGMLDFLLNWFSQEDNDSVIF 621
+L +L+ LQH LD F ++ +N++ C ++ LL + V
Sbjct: 117 CLLIFNLLKYFPTKLQHEILDRFTVMVEKCTTNQSVCCNCHLIYNLLEAIYKGQPMEVTT 176
Query: 622 QIAQLIQSIGGHSISGKDIRKIFALLRSEKVGMRRQYCSVLLTSLLTMLHEK--GPTAFF 679
+I +LI+ +G HS++ ++++K+F LL+SE+ S LLT+L + + + GP +F
Sbjct: 177 KILKLIERLGIHSVTVRELKKLFGLLKSEQGDYLPPTTSALLTTLQNISNSRNPGPQVYF 236
Query: 680 DLDGIDSGIILKTPLQWPLNKGFSFSCWLRVENF----------PRNGAMGLFSFLTENG 729
D DG DS IIL T +WP KGFSF W+R+E+F PR LFSFL+++G
Sbjct: 237 DFDGKDSCIILPTFDKWPFPKGFSFCTWVRIESFVDPTGTPEYKPR-----LFSFLSDSG 291
Query: 730 RGSLAVLAKEKLTYESINLKRQRVDLHV--NLVRRRWHFLCITHSIGRAFSAGSLLRCYL 787
G + ++L ++N + + V R W+F+ + +SI + + +R Y+
Sbjct: 292 CGIEVLFIYQQLQVLTVNNHQSKAVFQSPPTFVEREWYFVSVVYSIN--LISSNEIRIYI 349
Query: 788 DGDLVSSERCRYAKVSESLT-SCMIGAKFKMPHYEDNVLKFESIADSSPFFGQIGPVYLF 846
+G + AK S L S + FK+ N K S P +GQ+G +F
Sbjct: 350 NGQ-------QSAKSSIKLNISGTLWNHFKI----GNNSKKMSGERECPLYGQMGAFNIF 398
Query: 847 NDAISAEQVQSIYSLGPSYMYSFLDNEALPLSGDKVPSGILDAKDGLASRIIFGLNAQAS 906
++++S Q+Q+IY+LGP++ SF D E S S L S + N +A
Sbjct: 399 DESLSPSQIQAIYTLGPNFNTSFQDVEGSTKSAHTFES-------SLTSHLFLNYNCRAL 451
Query: 907 VGRMLFNVSPIVSHQLDKNSFEAAVIGGTQLCSRRLLQQIIYCVGGVSVLFPLITQFCKF 966
G + + +P + DKN ++A ++ C R ++ IIYC+GG+ VLFPLI Q
Sbjct: 452 DGDLCLDNTPDIGG--DKN-YDATLV-SINPCVSRDIKDIIYCLGGIKVLFPLIQQI--- 504
Query: 967 ENEEV-----------------------GESEKGARLTQTMRECVTTEVIELIASLLDEN 1003
N + + + +L Q++ +T +V+ L +L E+
Sbjct: 505 -NNPISPLSLELITNENNNNNNNNLSLSSQQQTLEQLQQSINIKLTNQVLALFKFMLKES 563
Query: 1004 LANQQQMHIVSGFSVLGFLLQSVPPRQLNLETLSALKRLFNVVSNSGLAELLVEEAISNI 1063
ANQ++M GFSV+G+LLQ + P L + +F +SN LVEE SN+
Sbjct: 564 EANQEEMLRCQGFSVMGYLLQQISPEYLTI----GCTNIFIDMSNQISDPTLVEEVYSNL 619
Query: 1064 FLNPLIWVYTVYKVQRELYMFLIQQFDNDPRLLKSLCRLPRVLDIIHQFYCDNVKPQSFV 1123
LN IW+ T Y++QR L + + Q + + + +LDI++ FY + S
Sbjct: 620 MLNFCIWIKTKYELQRNLLVIIKQIVFEKYDQVSDIITVQLILDIMNDFYWYD---DSKN 676
Query: 1124 ESNPLQHSVSEQVTGERPSKDEMHKIRXXXXXXGEMSLRQNIAAGDIKALIAFFEKSQDM 1183
E++ H ++ + +RPS + ++R + LR + DI+A+I F +D
Sbjct: 677 EAHRNHHFFNKDILSKRPSISNIRELRQILFEVLRILLRHQ-KSTDIQAIIKFLIYCKDY 735
Query: 1184 TCIEDVLHMVIRAVSQISLLASFLEQVNIIGGCQVFVNLLQRGSESIRLLSLQFIGRL 1241
+ +++ V+ F +++ +GG VF+ LL+ E +R ++Q I ++
Sbjct: 736 QQLIEMMEFVLGLNGNGHNCQQFFDEIMGLGGTDVFLTLLKIDDEGVRNTAIQLISKI 793
Score = 67.0 bits (162), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 44/143 (30%), Positives = 70/143 (48%), Gaps = 7/143 (4%)
Query: 1755 IQNLIQKDRVLTAVSDEAKYMKTSKMDRTQQIQELHSRIDENSLAESSSKKTFEDDIQSS 1814
I I T V +++ Y K R +++ ++ DE ++ + D+ +S
Sbjct: 1476 IVQYIDNQTYFTTVEEKSLYSWLEK--RKKKLTKVVLNTDEKEAESFNAAERKADNDLNS 1533
Query: 1815 LNSVLASYDSSRAEFHL-TCEEKQQNVAEKWIHMFRSLIDERGPWSTNPFPNCIVTHWKL 1873
++ L + R HL E + +W + RSL +ERGPW T + HWKL
Sbjct: 1534 IHVKLWMPECERRALHLYKARELRNQTTVQWRKILRSLTNERGPWGTTES----IVHWKL 1589
Query: 1874 DKTEDTWRRRPKLRQNYHFDENL 1896
DKTE++ R R KL++NY FDE+L
Sbjct: 1590 DKTENSSRMRIKLKRNYKFDEHL 1612
Query: CNT0002160
Subject: sp|Q9ESE1|LRBA_MOUSE Lipopolysaccharide-responsive and beige-likeanchor protein OS=Homo sapiens GN=LRBA PE=1 SV=4
Score = 521 bits (1343), Expect = e-148, Method: Compositional matrix adjust.
Identities = 292/743 (39%), Positives = 433/743 (58%), Gaps = 40/743 (5%)
Query: 2099 HRRWSVAKIKAVHWTRYLLRYTAIEIFFSDSVAPVFLNFASQKDAKDIGNLIVTTRNEYS 2158
H +W +I+++ RYLL+ TA+EIF ++ VA V NF K + N + S
Sbjct: 2130 HGKWLFTEIRSIFSRRYLLQNTALEIFMANRVA-VMFNFPDPATVKKVVNYLPRVGVGTS 2188
Query: 2159 FPKGSGRDKSGSISFVDRRVAQEMAETARESWRRRDITNFEYLMILNTLAGRSYNDLTQY 2218
F G ++ IS R + A + W+ R+I+NFEYLM LNT+AGRSYNDL QY
Sbjct: 2189 F----GLPQTRRISLASPRQLFK-ASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQY 2243
Query: 2219 PVFPWVLADHSSEVLDFNKSSTFRDLSKPVGALDTKRFEVFEDRYRNFCDPDIPSFYYGS 2278
PVFPWV+ ++ SE LD + FRDLSKP+GAL+ KR F +RY ++ D +P F+YG+
Sbjct: 2244 PVFPWVITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKFHYGT 2303
Query: 2279 HYSSMGIVLYYLLRLEPFTSLHRNLQGGKFDHADRLFQGVEGTYRNCLTNTSDVKELIPE 2338
HYS+ VL +LLR+EPFT+ NLQGGKFDHADR F + +RN +TSD+KELIPE
Sbjct: 2304 HYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPE 2363
Query: 2339 FFYMPEFLVNSNSYHLGVKQDGEPIGDVCLPPWAKGSPEEFIRRNREALESEYVSSNLHH 2398
F+Y+PE VN N+Y+LGV DG + DV LPPWAK S EEF+ NR ALESE+VS LH
Sbjct: 2364 FYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTS-EEFVHINRLALESEFVSCQLHQ 2422
Query: 2399 WIDLVFGYKQRGKPAVEAANIFYYLTYEGAVDLETTEDDLQRAAIEDQIANFGQTPIQIF 2458
WIDL+FGYKQ+G AV A N+FYYLTYEGAV+L + D + R A+E QI +FGQTP Q+
Sbjct: 2423 WIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLL 2482
Query: 2459 RKKHPRRGPPIPIAHPLYFA----PDSISLSSIVCNTS-QYSSAMLYVGLMDSNIVLVDE 2513
+ HP RG + ++ PL F D I + N+ + +A GL ++ V
Sbjct: 2483 IEPHPPRGSAMQVS-PLMFTDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTA 2541
Query: 2514 GLNLSVKMWLTTQLQSGG----NFTFSGSQDPFFGVGSDILSPRKIGIPVPENVELGAQC 2569
+V W G + DP + + R+I + +++++ +QC
Sbjct: 2542 NRLFAVNKWHNLPAHQGAVQDQPYQLPVEIDPLIASNTG-MHRRQITDLLDQSIQVHSQC 2600
Query: 2570 FATMQTPSENFLISCGNWENSFQVISLSDGRMVQSIRQHKDVVSCVAVTSD----GSILA 2625
F T +++ CG W+ SF+V S GR++Q + H DVV+C+A + +
Sbjct: 2601 FVI--TSDNRYILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYIL 2658
Query: 2626 TGSYDTTVMVWEVFRGK-TAEKRIRNSQSELPRKNYVIIETPCHILCGHDDIITCLYVNH 2684
+GS D T+++W + GK + S++ PR IL GHD +TC V
Sbjct: 2659 SGSRDATLLLW-YWNGKCSGIGDNPGSETAAPRA----------ILTGHDYEVTCAAVCA 2707
Query: 2685 ELDIIISGSKDGTCVFHTLREGRYVRSLRHPSGSPITKLV-VSQRGQIVIYADDDLSLHL 2743
EL +++SGS++G C+ H++ G +R+L P KL+ S+ G VI+ ++ L
Sbjct: 2708 ELGLVLSGSQEGPCLIHSMN-GDLLRTLEGPENCLKPKLIQASREGHCVIFYENGL-FCT 2765
Query: 2744 YSINGKYVAASESNGRLNAVQLSRCGEFLVGAGDQGQIVVRSMNTLEVVKKYQGVGKVLT 2803
+S+NGK A E++ + A+QLSR G++L+ GD+G +VVR ++ L+ + Y G +
Sbjct: 2766 FSVNGKLQATMETDDNIRAIQLSRDGQYLLTGGDRGVVVVRQVSDLKQLFAYPGCDAGIR 2825
Query: 2804 SLAVTPEE-CFLAGTKDGSLLVY 2825
++A++ ++ C ++G GS++++
Sbjct: 2826 AMALSYDQRCIISGMASGSIVLF 2848
Score = 206 bits (525), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 206/878 (23%), Positives = 398/878 (45%), Gaps = 92/878 (10%)
Query: 531 SSESLLDALLDMLVDGKFNVKMSPMIKNEDVIILYLIVLQKSSESLQHHGLDIFQQLLRD 590
S+ +++ + ++LV G+F+++M+ +I+ + I + +L+K + Q +F +L+
Sbjct: 61 SNRDIVETVFNLLVGGQFDLEMNFIIQEGESINCMVDLLEKCDITCQAEVWSMFTAILKK 120
Query: 591 SISNRASCVRAGMLDFLLNWFSQEDNDSVIFQIAQLIQSIGGHSISGKDIRKIFALLRSE 650
SI N C G+++ +L + DN + + ++ + ++++ ++++ F+ L+ +
Sbjct: 121 SIRNLQVCTEVGLVEKVLGKIEKVDN-MIADLLVDMLGVLASYNLTVRELKLFFSKLQGD 179
Query: 651 KVGMRRQYCSVLLTSLLTMLHEKGPTAFFDLDGIDSGIILKTPL-QWPLNKGFSFSCWLR 709
K G + LL+ L M + GP AFF+ G + I P+ +WP GF+F WLR
Sbjct: 180 K-GRWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIALPPIAKWPYQNGFTFHTWLR 238
Query: 710 VE-----NFPRNGAMGLFSFLTENGRGSLAVLAKEKLTYESINLKRQRVD--LHVNLVRR 762
++ N ++ L+ F T G G A L SI K + + + +
Sbjct: 239 MDPVNNINVDKDKPY-LYCFRTSKGLGYSAHFVGGCLIVTSIKSKGKGFQHCVKFDFKPQ 297
Query: 763 RWHFLCITHSIGRAFSAGSLLRCYLDGDLVS-SERCRYAKVSESLTSCMIGAKFKMPHYE 821
+W+ + I H R S LRCY++G+L S E + S++ C +G+
Sbjct: 298 KWYMVTIVHIYNRW--KNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSS------- 348
Query: 822 DNVLKFESIADSSPFFGQIGPVYLFNDAISAEQVQSIYSLGPSYMYSF-LDNEALPLSGD 880
E+ + F GQ+ VYLF++A++A Q+ +IY LG Y +F E+ +
Sbjct: 349 ------ETADANRVFCGQMTAVYLFSEALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAE 402
Query: 881 KVPSGILDAKDGLASRIIFGLNAQASVGRMLFNVSPIVSHQLDKNSFEAAVIGGTQLCSR 940
+ D K L+S I F N +A+ ++ SP + + +S A ++ +
Sbjct: 403 HHKLLLYDGK--LSSAIAFTYNPRATDAQLCLESSPKDNPSIFVHSPHALMLQDVKAVLT 460
Query: 941 RLLQQIIYCVGGVSVLFPLITQFCKFENEEVGESEKGARLTQTMRECVTTEVIELIASLL 1000
+Q ++ +GGV VLFPL Q + L+ + + + ++ I LL
Sbjct: 461 HSIQSAMHSIGGVQVLFPLFAQL-----------DYRQYLSDEIDLTICSTLLAFIMELL 509
Query: 1001 DENLANQQQMHIVSGFSVLGFLLQSVPPRQLNLETLSALKRLFNVVSNSGLAELLVEEAI 1060
++A Q+QM GF V+G+ L+ ++ L +SN L+++
Sbjct: 510 KNSIAMQEQMLACKGFLVIGYSLEKSSKSHVSRAVLELCLAFSKYLSNLQNGMPLLKQLC 569
Query: 1061 SNIFLNPLIWVYTVYKVQRELYMFLIQQFDNDPRLLKSLCRLPRVLDIIH--QFYCDNVK 1118
++ LNP IW++T KVQ LY +L +F + ++ R+ VL I+H ++Y V
Sbjct: 570 DHVLLNPAIWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWAVN 629
Query: 1119 PQSFVESNPLQHSVSEQVTGERPSKDEMHKIRXXXXXXGEMSLRQN--IAAGDIKALIAF 1176
PQ P + + G RP++ EM +R + + ++ + +++A++ +
Sbjct: 630 PQDRSGITP------KGLDGPRPNQKEMLSLRAFLLMFIKQLVMKDSGVKEDELQAILNY 683
Query: 1177 FEKSQDMTCIEDVLHMVIRAVSQI--SLLASFLEQVNIIGGCQVFVNLLQRGSESIRLLS 1234
+ + DVL +++ +S+ S++ +F +Q N G +V LL SE IR+ +
Sbjct: 684 LLTMHEDDNLMDVLQLLVALMSEHPNSMIPAF-DQRN---GLRVIYKLLASKSEGIRVQA 739
Query: 1235 LQFIGRLLVGLPAEKKGSRFFNLPMGRSRSISDNQRKIRMQPIFLALSNRLFCFPQTDNL 1294
L+ +G L L ++K +F L+ RL QT+ +
Sbjct: 740 LKAMGYFLKHLAPKRKAEVMLG------------------HGLFSLLAERLML--QTNLI 779
Query: 1295 CAT----LFDVLLGGASPKQVLQRHNHVE-RVRSKGSHFLLPQMLPLIFRYLSGCKDAPA 1349
T LF++L+ + + ++H + V+ + PQ+L +I L P
Sbjct: 780 TMTTYNVLFEILIEQIGTQVIHKQHPDPDSSVKIQN-----PQILKVIATLLRNSPQCPE 834
Query: 1350 RMKIIR----DLLGLLDSNASNIEAFMEYG-WNAWLTS 1382
M++ R D++ L +++ N + ++ W W+ S
Sbjct: 835 SMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLS 872
Query: CNT0002160
Subject: sp|Q9W4E2|NBEA_DROME Neurobeachin OS=Drosophila melanogaster GN=rganchor protein OS=Mus musculus GN=Lrba PE=1 SV=1
Score = 520 bits (1340), Expect = e-147, Method: Compositional matrix adjust.
Identities = 294/742 (39%), Positives = 430/742 (57%), Gaps = 38/742 (5%)
Query: 2099 HRRWSVAKIKAVHWTRYLLRYTAIEIFFSDSVAPVFLNFASQKDAKDIGNLIVTTRNEYS 2158
H +W +I+++ RYLL+ TA+EIF ++ VA V NF K + N + S
Sbjct: 2123 HGKWLFTEIRSIFSRRYLLQNTALEIFMANRVA-VMFNFPDPATVKKVVNYLPRVGVGTS 2181
Query: 2159 FPKGSGRDKSGSISFVDRRVAQEMAETARESWRRRDITNFEYLMILNTLAGRSYNDLTQY 2218
F G ++ IS R + A + W+ R+I+NFEYLM LNT+AGRSYNDL QY
Sbjct: 2182 F----GLPQTRRISLATPRQLFK-ASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQY 2236
Query: 2219 PVFPWVLADHSSEVLDFNKSSTFRDLSKPVGALDTKRFEVFEDRYRNFCDPDIPSFYYGS 2278
PVFPWV+ ++ SE LD S FRDLSKP+GAL+ KR F +R+ ++ D +P F+YG+
Sbjct: 2237 PVFPWVITNYESEELDLTLPSNFRDLSKPIGALNPKRAAFFAERFESWEDDQVPKFHYGT 2296
Query: 2279 HYSSMGIVLYYLLRLEPFTSLHRNLQGGKFDHADRLFQGVEGTYRNCLTNTSDVKELIPE 2338
HYS+ VL +LLR+EPFT+ NLQGGKFDHADR F V +RN +TSD+KELIPE
Sbjct: 2297 HYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSVSRAWRNSQRDTSDIKELIPE 2356
Query: 2339 FFYMPEFLVNSNSYHLGVKQDGEPIGDVCLPPWAKGSPEEFIRRNREALESEYVSSNLHH 2398
F+Y+PE VN N+Y+LGV DG + DV LPPWAK S EEF+R NR ALESE+VS LH
Sbjct: 2357 FYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTS-EEFVRINRLALESEFVSCQLHQ 2415
Query: 2399 WIDLVFGYKQRGKPAVEAANIFYYLTYEGAVDLETTEDDLQRAAIEDQIANFGQTPIQIF 2458
WIDL+FGYKQ+G AV A N+FYYLTYEGAV+L + D + R A+E QI +FGQTP Q+
Sbjct: 2416 WIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLL 2475
Query: 2459 RKKHPRRGPPIPIAHPLYFA----PDSISLSSIVCNTS-QYSSAMLYVGLMDSNIVLVDE 2513
+ HP RG + A PL F D I + N+ + +A GL ++ V
Sbjct: 2476 IEPHPPRGSAMQ-ASPLMFTDQAQQDVIMVLKFPSNSPVTHVAANTQPGLAMPAVITVTA 2534
Query: 2514 GLNLSVKMWLTTQLQSGG----NFTFSGSQDPFFGVGSDILSPRKIGIPVPENVELGAQC 2569
+V W G + DP G+ R++ + +++++ +QC
Sbjct: 2535 NRLFAVNKWHNLPAHQGAVQDQPYQLPVEIDPLIACGTGT-HRRQVTDLLDQSIQVHSQC 2593
Query: 2570 FATMQTPSENFLISCGNWENSFQVISLSDGRMVQSIRQHKDVVSCVAVTSD----GSILA 2625
F T +++ CG W+ SF+V S G+++Q + H DVV+C+A + +
Sbjct: 2594 FVI--TSDNRYILVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESYIGGNCYIL 2651
Query: 2626 TGSYDTTVMVWEVFRGKTAEKRIRNSQSELPRKNYVIIETPCHILCGHDDIITCLYVNHE 2685
+GS D T+++W + GK++ N E TP IL GHD ITC V E
Sbjct: 2652 SGSRDATLLLW-YWNGKSSGIG-DNPGGE--------TATPRAILTGHDYEITCAAVCAE 2701
Query: 2686 LDIIISGSKDGTCVFHTLREGRYVRSLRHPSGSPITKLV-VSQRGQIVIYADDDLSLHLY 2744
L +++SGS++G C+ H++ G +R+L P KL+ S+ G VI+ ++ +
Sbjct: 2702 LGLVLSGSQEGPCLIHSMN-GDLLRTLEGPENCLKPKLIQASREGHCVIFYENG-CFCTF 2759
Query: 2745 SINGKYVAASESNGRLNAVQLSRCGEFLVGAGDQGQIVVRSMNTLEVVKKYQGVGKVLTS 2804
S+NGK A E++ + A+QLSR G++L+ GD G ++VR ++ L+ + Y G + +
Sbjct: 2760 SVNGKLQATVETDDHIRAIQLSRDGQYLLTGGDNGVVIVRQVSDLKQLFAYPGCDAGIRA 2819
Query: 2805 LAVT-PEECFLAGTKDGSLLVY 2825
+A++ + C ++G GS++++
Sbjct: 2820 MALSFDQRCIISGMASGSIVLF 2841
Score = 207 bits (528), Expect = 6e-52, Method: Compositional matrix adjust.
Identities = 211/881 (23%), Positives = 398/881 (45%), Gaps = 98/881 (11%)
Query: 531 SSESLLDALLDMLVDGKFNVKMSPMIKNEDVIILYLIVLQKSSESLQHHGLDIFQQLLRD 590
S+ +++ + ++LV G+F+++M+ +I+ + I+ + +L+K + Q +F +L+
Sbjct: 61 SNRDIVETVFNLLVGGQFDLEMNFIIQEGESIMCMVELLEKCDVTCQAEVWSMFTAILKK 120
Query: 591 SISNRASCVRAGMLDFLLNWFSQEDNDSVIFQI-AQLIQSIGGHSISGKDIRKIFALLRS 649
SI N C G+++ +L E DS+I + ++ + ++++ ++++ F+ L+
Sbjct: 121 SIRNLQVCTEVGLVEKVLGKI--EKVDSMIADLLVDMLGVLASYNLTVRELKLFFSKLQG 178
Query: 650 EKVGMRRQYCSVLLTSLLTMLHEKGPTAFFDLDGIDSGIILKTPL-QWPLNKGFSFSCWL 708
+K G + LL+ L M + GP AFF+ G + I P+ +WP GF+F WL
Sbjct: 179 DK-GQWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIALPPIARWPYQNGFTFHTWL 237
Query: 709 RVE-----NFPRNGAMGLFSFLTENGRGSLAVLAKEKLTYESINLKRQRVD--LHVNLVR 761
R++ N ++ L+ F T G G A L SI K + + +
Sbjct: 238 RMDPVNNINVDKDKPY-LYCFRTSKGLGYSAHFVGGCLIITSIKSKGKGFQHCVKFDFKP 296
Query: 762 RRWHFLCITHSIGRAFSAGSLLRCYLDGDLVS-SERCRYAKVSESLTSCMIGAKFKMPHY 820
++W+ + I H R S LRCY++G+L S E + S++ C +G+
Sbjct: 297 QKWYMVTIVHIYNRW--KNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSS------ 348
Query: 821 EDNVLKFESIADSSPFFGQIGPVYLFNDAISAEQVQSIYSLGPSYMYSF-LDNEALPLSG 879
E+ + F GQ+ VYLF+DA++A Q+ +IY LG Y +F E+
Sbjct: 349 -------ETADANRVFCGQMTAVYLFSDALNAAQIFAIYQLGLGYKGTFKFKAESDLFLA 401
Query: 880 DKVPSGILDAKDGLASRIIFGLNAQASVGRMLFNVSPIVSHQLDKNSFEAAVIGGTQLCS 939
+ + D K L+S I F N +A+ ++ SP + + +S A ++ +
Sbjct: 402 EHHKLLLYDGK--LSSAIAFMYNPRATDAQLCLESSPKDNPSIFVHSPHALMLQDVKAVL 459
Query: 940 RRLLQQIIYCVGGVSVLFPLITQFCKFENEEVGESEKGARLTQTMRECVTTEVIELIASL 999
+Q ++ +GGV VLFPL Q + L+ + + T ++ I L
Sbjct: 460 THSIQSAMHSIGGVQVLFPLFAQL-----------DYKQYLSDEVDLTICTTLLAFIMEL 508
Query: 1000 LDENLANQQQMHIVSGFSVLGFLLQSVPPRQLNLETLSALKRLFNVVSNSGLAELLVEEA 1059
L ++A Q+QM GF V+G+ L+ ++ L +SN L+++
Sbjct: 509 LKNSIAMQEQMLACKGFLVIGYSLEKSSKSHVSRAVLELCLAFSKYLSNLQNGMPLLKQL 568
Query: 1060 ISNIFLNPLIWVYTVYKVQRELYMFLIQQFDNDPRLLKSLCRLPRVLDIIH--QFYCDNV 1117
+I LNP +W++T KVQ LY +L +F + ++ R+ VL I+H ++Y V
Sbjct: 569 CDHILLNPAVWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWAV 628
Query: 1118 KPQSFVESNPLQHSVSEQVTGERPSKDEMHKIRXXXXXXGEMSLRQ------NIAAGDIK 1171
PQ P + + G RP++ E+ +R M ++Q + +++
Sbjct: 629 NPQDRSGITP------KGLDGPRPNQKEILSLRAFLL----MFIKQLVMKDSGVKEDELQ 678
Query: 1172 ALIAFFEKSQDMTCIEDVLHMVIRAVSQI--SLLASFLEQVNIIGGCQVFVNLLQRGSES 1229
A++ + + + DVL +++ +++ S++ +F +Q N G +V LL SE
Sbjct: 679 AILNYLLTMHEDDNLMDVLQLLVALMAEHPNSMIPAF-DQRN---GLRVIYKLLASKSEG 734
Query: 1230 IRLLSLQFIGRLLVGLPAEKKGSRFFNLPMGRSRSISDNQRKIRMQPIFLALSNRLFCFP 1289
IR+ +L+ +G L L ++K +F L+ RL
Sbjct: 735 IRVQALKALGYFLKHLAPKRKAEVMLG------------------HGLFSLLAERLML-- 774
Query: 1290 QTDNLCATLFDVL---LGGASPKQVLQRHNHVERVRSKGSHFLLPQMLPLIFRYLSGCKD 1346
QT+ + T+++VL L QV+ + + K + PQ+L +I L
Sbjct: 775 QTNLITMTMYNVLFEILIEQICTQVIHKQHPDPDSTVKIQN---PQILKVIATLLRNSPQ 831
Query: 1347 APARMKIIR----DLLGLLDSNASNIEAFMEYG-WNAWLTS 1382
P M++ R D++ L +++ N + ++ W W+ S
Sbjct: 832 CPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLS 872
Query: CNT0002160
Subject: sp|Q6ZQA0|NBEL2_MOUSE Neurobeachin-like protein 2 OS=Mus musculusPE=1 SV=3
Score = 496 bits (1277), Expect = e-139, Method: Compositional matrix adjust.
Identities = 292/769 (37%), Positives = 438/769 (56%), Gaps = 62/769 (8%)
Query: 2092 LMRCVKRHRRWSVAKIKAVHWTRYLLRYTAIEIFFSDSVAPVFLNFASQKDAKDIGNLIV 2151
L C H +W ++++A+ RYLL+ A+EIF + + +F F Q K + +
Sbjct: 2828 LKYCDHLHGKWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFA-FPDQHTVKKV--IKA 2884
Query: 2152 TTRNEYSFPKGSGRDKSGSISFVDRRVAQEMAETARESWRRRDITNFEYLMILNTLAGRS 2211
R G + + S+ R++ + T + W+RR+I+NFEYLM LNT+AGR+
Sbjct: 2885 LPRVGVGIKYGIPQTRRASM-MSPRQLMRNSNMTQK--WQRREISNFEYLMFLNTIAGRT 2941
Query: 2212 YNDLTQYPVFPWVLADHSSEVLDFNKSSTFRDLSKPVGALDTKRFEVFEDRYRNFCDPDI 2271
YNDL QYP+FPWVL ++ S+ LD + S +RDLSKP+GAL+ R FE+RY ++ I
Sbjct: 2942 YNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWDSDTI 3001
Query: 2272 PSFYYGSHYSSMGIVLYYLLRLEPFTSLHRNLQGGKFDHADRLFQGVEGTYRNCLTNTSD 2331
P F+YG+HYS+ L +L+R+EPFT++ LQGGKFD+ DRLF V +++NC +TSD
Sbjct: 3002 PPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNCQRDTSD 3061
Query: 2332 VKELIPEFFYMPEFLVNSNSYHLGVKQDGEPIGDVCLPPWAKGSPEEFIRRNREALESEY 2391
VKELIPE++++PE NS+ Y LG ++DG + D+ LPPWAK SPEEF+R NR ALESE+
Sbjct: 3062 VKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAK-SPEEFVRINRMALESEF 3120
Query: 2392 VSSNLHHWIDLVFGYKQRGKPAVEAANIFYYLTYEGAVDLETTEDDLQRAAIEDQIANFG 2451
VS LH WIDL+FGYKQRG A+ A N+FYYLTYEG+VDL+ D + R A+E+QI NFG
Sbjct: 3121 VSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFG 3180
Query: 2452 QTPIQIFRKKHPRRGPPIPIAHPLYFAPDSISLSSIVCNTSQYS--------SAMLYVGL 2503
QTP Q+ + HP R + ++ P+ F+ ++ +C ++ SA Y L
Sbjct: 3181 QTPSQLLMEPHPPRSSAMHLS-PMMFS----AMPEDLCQMLKFYQNSPVIHISANTYPQL 3235
Query: 2504 MDSNIVLVDEGLNLSVKMW---LTTQLQS----------GGNFTFSGSQDPFFGV----- 2545
++V V G +V W T +QS G N + DP V
Sbjct: 3236 SLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPL--TIDPVLAVHGTNN 3293
Query: 2546 GSDILSPRKIGIPVPENVELGAQCFATMQTPSENFLISCGNWENSFQVISLSDGRMVQSI 2605
S+ S R +G + +++ + CF T T FLI+CG W+NSF+V + ++VQ +
Sbjct: 3294 NSNAASRRHLGDNFSQMLKIRSNCFVT--TVDSRFLIACGFWDNSFRVFATETAKIVQIV 3351
Query: 2606 RQHKDVVSCVA-----VTSDGSILATGSYDTTVMVWEVFRGKTAEKRIRNSQSELPRKNY 2660
H VV+C+A +TSD I A+GS D TV++W + +T QS + +
Sbjct: 3352 FGHFGVVTCMARSECNITSDCYI-ASGSADCTVLLWH-WNART--------QSIVGEGD- 3400
Query: 2661 VIIETPCHILCGHDDIITCLYVNHELDIIISGSKDGTCVFHTLREGRYVRSLRHPSGSPI 2720
+ TP L GH+ +T + ++ EL +++SGS +G + HT G +RSL P+
Sbjct: 3401 --VPTPRATLTGHEQAVTSVVISAELGLVVSGSSNGPVLIHTTF-GDLLRSLDPPAEFHS 3457
Query: 2721 TKLVVSQRGQIVIYADDDLSLHLYSINGKYVAASESNGRLNAVQLSRCGEFLVGAGDQGQ 2780
+L+ R ++ D ++ Y+INGK + N L + LSR GE+L+ AGD+G
Sbjct: 3458 PELITMSREGFIVINYDKGNVAAYTINGKKLRHETHNDNLQCMLLSRDGEYLMTAGDRGI 3517
Query: 2781 IVVRSMNTLEVVKKYQGVGKVLTSLAVTPEECF-LAGTKDGSLLVYSIE 2828
+ V L + + + SLA+T ++ + LAG GS++V+ I+
Sbjct: 3518 VEVWRTFNLAPLYAFPACNAGIRSLALTHDQKYLLAGLSTGSIIVFHID 3566
Score = 98.2 bits (243), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 115/516 (22%), Positives = 232/516 (44%), Gaps = 73/516 (14%)
Query: 891 DG-LASRIIFGLNAQASVGRMLFNVSPIVSHQLDKNSFEAAVIGGTQLCSRRLLQQIIYC 949
DG L++ I+F N A+ G++ SP + ++ A ++ + + +
Sbjct: 401 DGKLSNAIVFMYNPVATDGQLCLQSSPKGNVSYFVHTPHALMLQDVKAVVTHSIHCTLNS 460
Query: 950 VGGVSVLFPLITQFCKFENEEVGESEKGARLTQTMRECVTTEVIELIASLLDENLANQQQ 1009
+GG+ VLFPL +Q +E +G+ ++ L C ++++ I L++ + QQ
Sbjct: 461 IGGIQVLFPLFSQL-DMAHEGLGDIKRDPTL------C--SKLLGFICELVETSQTVQQH 511
Query: 1010 MHIVSGFSVLGFLLQSVPPRQLNLETLSALKRL--FNVVSNSGLAELLVEEAISNIFLNP 1067
M GF V+ F+LQ L LE L + L + V S ++LL+++ + ++ NP
Sbjct: 512 MIQNRGFLVISFMLQRSSREHLTLEVLGSFLNLTKYLVTCLSANSDLLLKQLLDHVLFNP 571
Query: 1068 LIWVYTVYKVQRELYMFLIQQFDNDPRLLKSLCRLPRVLDIIHQ----FYCDNVKPQSFV 1123
+W+YT VQ LY +L +F +D ++ ++ R+ VL +H ++ N + +S +
Sbjct: 572 ALWIYTPANVQARLYSYLATEFLSDTQIYSNVRRVSTVLQTVHTLKYYYWVVNPRAKSGI 631
Query: 1124 ESNPLQHSVSEQVTGERPSKDEMHKIRXXXXXXGEMSLRQNIAAG------DIKALIAFF 1177
+ + + G RP++ ++ IR + L+Q I G ++++++ +
Sbjct: 632 --------IPKGLDGPRPAQKDILAIRAYIL----LFLKQLIMIGNGVKEDELQSILNYL 679
Query: 1178 EKSQDMTCIEDVLHMVIRAVSQISLLASFLEQVNIIGGCQVFVNLLQRGSESIRLLSLQF 1237
+ + DVL M+I +S+ +S + ++ G + LL S+ IRL +L+
Sbjct: 680 TTMHEDENLHDVLQMLISLMSEHP--SSMVPAFDVKHGVRSIFKLLAAESQLIRLQALKL 737
Query: 1238 IGRLLVGLPAEKKGSRFFNLPMGRSRSISDNQRKIRMQP--IFLALSNRLFCFPQTDNLC 1295
+G L SRS + + M P ++ L+ RL + ++ +L
Sbjct: 738 LGFFL-------------------SRSTHKRKYDV-MSPHNLYTLLAERLLLYEESLSLP 777
Query: 1296 A--TLFDVLLGGASPKQVLQRHNHVERVRSKGSHFLL--PQMLPLIFRYLSGCKDAPARM 1351
L++++ S + + RH E SH+ L P +L ++ + K + +
Sbjct: 778 TYNVLYEIMTEHISQQILYTRHPEPE------SHYRLENPMILKVVATLIRQSKQTESLI 831
Query: 1352 KI----IRDLLGLLDSNASNIEAFMEYG-WNAWLTS 1382
+ ++D+ L +SN N ++ W WL +
Sbjct: 832 DVKKLFLQDMTLLCNSNRENRRTVLQMSVWQEWLIA 867
Score = 72.4 bits (176), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 52/195 (26%), Positives = 89/195 (45%), Gaps = 25/195 (12%)
Query: 688 IILKTPLQWPLNKGFSFSCWLRVE-----NFPRNGAMGLFSFLTENGRGSLAVLAKEKLT 742
++L +WP GF+F+ W R++ N R L+ F T G G A L
Sbjct: 1 MVLPPLAKWPYENGFTFTTWFRLDPINSVNIEREKPY-LYCFKTSKGVGYTAHFVGNCLV 59
Query: 743 YESINLKRQRVD--LHVNLVRRRWHFLCITHSIGRAFSAGSLLRCYLDGDLVSS-ERCRY 799
S+ +K + + R+W+ + I + R S ++C ++G L SS E +
Sbjct: 60 LTSMKVKGKGFQHCVKYEFQPRKWYMIAIVYIYNRW--TKSEIKCLVNGQLASSTEMAWF 117
Query: 800 AKVSESLTSCMIGAKFKMPHYEDNVLKFESIADSSPFFGQIGPVYLFNDAISAEQVQSIY 859
++ C IGA ++ E+ V F GQ+ +YLF++A++ +Q+ +++
Sbjct: 118 VSTNDPFDKCYIGATPELD--EERV-----------FCGQMSAIYLFSEALTTQQICAMH 164
Query: 860 SLGPSYMYSF-LDNE 873
LGP Y F DNE
Sbjct: 165 RLGPGYKSQFRFDNE 179
Query: CNT0002160
Subject: sp|Q6ZS30|NBEL1_HUMAN Neurobeachin-like protein 1 OS=Homo sapiensGN=Nbeal2 PE=2 SV=2
Score = 485 bits (1249), Expect = e-136, Method: Compositional matrix adjust.
Identities = 294/788 (37%), Positives = 432/788 (54%), Gaps = 79/788 (10%)
Query: 2101 RWSVAKIKAVHWTRYLLRYTAIEIFFSDSVAPVFLNFASQKDAKDIGNLIVTTRNE-YSF 2159
R +A+++ VH R+ LR +A+E+FF D + FLNF + A + R + Y
Sbjct: 1955 RRPLAQLREVHLRRFNLRRSALELFFIDQ-SNYFLNFPHKVAASSASSPCQAPRPQLYPI 2013
Query: 2160 PKGSG----------RDKSGSISFVDRRVAQEM--AETARESWRRRDITNFEYLMILNTL 2207
P + R + + ++ R EM A + W +R+I+NFEYLM LNT+
Sbjct: 2014 PSHTQLRNQVYSLLLRLRPPTQGYLSSRSPLEMLRASGLTQKWVQREISNFEYLMQLNTI 2073
Query: 2208 AGRSYNDLTQYPVFPWVLADHSSEVLDFNKSSTFRDLSKPVGALDTKRFEVFEDRYRNFC 2267
AGR+YNDL+QYPVFPWVL D+ S VLD + + FRDLSKP+G ++ K ++ ++Y +F
Sbjct: 2074 AGRTYNDLSQYPVFPWVLQDYVSPVLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFE 2133
Query: 2268 DP--DIPSFYYGSHYSSMGIVLYYLLRLEPFTSLHRNLQGGKFDHADRLFQGVEGTYRNC 2325
DP I F+YG+HYS+ V++YL+R+EPFTSLH LQ G+FD +DR F V ++
Sbjct: 2134 DPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQAR 2193
Query: 2326 LTNTSDVKELIPEFFYMPEFLVNSNSYHLGVKQ-DGEPIGDVCLPPWAKGSPEEFIRRNR 2384
L + +DVKELIPEFFY P+FL N N + LG Q E +GDV LPPWA GSPE+FI+++R
Sbjct: 2194 LESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWA-GSPEDFIQKHR 2252
Query: 2385 EALESEYVSSNLHHWIDLVFGYKQRGKPAVEAANIFYYLTYEGAVDLETTEDDLQRAAIE 2444
+ALESEYVS++LH WIDL+FGYKQRG A EA N+FYY TYEGAVDL+ D+ +R A+E
Sbjct: 2253 QALESEYVSTHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVADERERKALE 2312
Query: 2445 DQIANFGQTPIQIFRKKHPRRGPPIPIAHPL-------------------YFAPDSISLS 2485
I+NFGQTP Q+ ++ HP R A+ L +FA
Sbjct: 2313 GIISNFGQTPCQLLKEPHPPRLSAEEAANRLARLDTNSPSIFQNLNQLKAFFAEVVSEAV 2372
Query: 2486 SIVCNTSQYSSAMLYVGLMDSN-IVLVDEGLNLSVKMWLTTQLQSGGNFTFSGSQDPFFG 2544
+V + + ++ S+ +V V L WL FTF S+DP G
Sbjct: 2373 PLVLALVPHRQSHSFITQSSSDMLVTVSASGLLGTHTWLPYDRNINNYFTF--SKDPTMG 2430
Query: 2545 VGSDILSPRK---IGIPVPENVELGAQCFATMQTPSENFLISCGNWENSFQVISLSDGRM 2601
SP+ + P + + AQ A P L S G+W+ S +V SL GR+
Sbjct: 2431 ------SPKVQKLLSGPWVSDSGVSAQALAV--APDGKLLFSGGHWDGSLRVTSLPRGRL 2482
Query: 2602 VQSIRQHKDVVSCVAVTSDGSILATGSYDTTVMVWEVFRGKTAEKRIRNSQSELPRKNYV 2661
+ + +H D+V+C+A+ + G L +GS DTT MVW + + QS L +
Sbjct: 2483 LNQLSRHLDIVTCLALDTCGIYLISGSRDTTCMVWRLLQ-----------QSGL---SAG 2528
Query: 2662 IIETPCHILCGHDDIITCLYVNHELDIIISGSKDGTCVFHTLREGRYVRSLRHPSGS--- 2718
+ P +L GH ++C+ ++ ELD+ +SGS+DGT + HT+R G++V +LR P +
Sbjct: 2529 LAPKPVQVLYGHVAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPPGATLPG 2588
Query: 2719 PITKLVVSQRGQIVIY--------ADDDLSLHLYSINGKYVAASESNGRLNAVQLSRCGE 2770
PI+ L + GQIV+ A SLHLYS+NG+ A+ + A+ ++ +
Sbjct: 2589 PISHLALGAEGQIVVQSSACERPGAQVTYSLHLYSVNGRLRASVTLTEQPTALTVAE--D 2646
Query: 2771 FLVGAGDQGQIVVRSMNTLEVVKKYQGVGKVLTSLAVTPEEC-FLAGTKDGSLLVYSIEN 2829
F++ Q + + +N L + + S++VT E L G +DG L+V
Sbjct: 2647 FVLLGTAQCSLHILHLNKLRPAVPPLPMKVPVHSVSVTKERSHVLVGLEDGKLIVVGAGQ 2706
Query: 2830 PQIRKNSH 2837
P ++S
Sbjct: 2707 PSEVRSSQ 2714
Score = 119 bits (297), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 166/754 (22%), Positives = 300/754 (39%), Gaps = 174/754 (23%)
Query: 432 EKSFVDLSIDLLVGMRDMLQA-NQAYYQTLFRDGECFLHVVSLLNSN------------- 477
E++ V L + +L + ML ++ Q F CF H++ L+ ++
Sbjct: 296 EEALVTLRVSMLDAIPMMLACEDRPVLQATFLSNNCFEHLIRLIQNSKLYLQARAPPEGD 355
Query: 478 -------LDEANGEK--------LVLNVLQTLTCLLASNDTSKAAFRTLAGKGYQTLQSL 522
L E + +K + ++V++ LTC+++ + ++K F+ G YQ LQ +
Sbjct: 356 SDLATWLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSGSPSAKEVFKERIG--YQHLQEV 413
Query: 523 LLDFCQWHS--SESLLDALLDMLVDGKFNVKMSPMIKNEDVIILYLIVLQKSSESLQHHG 580
L Q H + LL LL+M V+G ++ P I+NE ++ VL + +L
Sbjct: 414 L----QSHGPPTHRLLQELLNMAVEGDHSMHPPPPIRNEQPVL----VLMQWLPALPTAE 465
Query: 581 LDIF--QQL--LRDSI-SNRASCVRAGMLDFLLNWFSQEDNDSVIFQIAQLIQSIGGHSI 635
L +F Q+L L DS ++R +CV+AG++ +LL + Q L +
Sbjct: 466 LRLFLAQRLWWLCDSCPASRTTCVQAGLVGYLLETLNTGTALGARCQEQLLALLQALGRV 525
Query: 636 SGKDIRKIFALLR-----SEKVGMRRQ---YCSVLLTSLLTMLHEKGPTA---FFDLDGI 684
S + + L SE G Q + ++ +L M +GP +FDL
Sbjct: 526 SLRPLELRRLLRPPPGLDSESSGNESQKARHAGAVIRALSGMARHRGPARALRYFDLTPS 585
Query: 685 DSGIILKTPLQWPLNKGFSFSCWLRV---ENFPRNGA------MGLFSFLTENGRGSLAV 735
+GI++ +WP GF+F WL + E P + L+SF T +G G A
Sbjct: 586 MAGIMVPPVQRWP-GAGFTFHAWLCLQSSEAVPTSAPSRPLQRKQLYSFFTSSGSGFEAF 644
Query: 736 LAKEKLTYESINLKRQRVDLH---VNLVRRRWHFLCITHSIGRAFSAGSLLRCYLDGDLV 792
++ +++ V ++ V+ WH + I H GR + +L+ + DG LV
Sbjct: 645 FTAAGTLVVAVCTRKEYVTVNLPEVSFADSAWHCVAIVHVPGRRPFSQNLVNVFKDGHLV 704
Query: 793 SSERCRYAKVSESLTSCMIGA-----------------KFKMPHYEDNVLKFESIADS-- 833
+ R+ +SE +SC IG+ + H ++ + +S+ S
Sbjct: 705 KTVPFRFPSLSEPFSSCCIGSAGHRTTTTTTGLPASSVSTALAHTHPSLTRSQSVPASTG 764
Query: 834 -----------------------------SP--FFGQIGPVYLFNDAISAEQVQSIYSLG 862
SP G++G V +F++A+ ++ + SLG
Sbjct: 765 LGWGPGLGTPLQEGSVSSTLAGTQDTRWGSPTSLEGELGAVAIFHEALQPSALRVLCSLG 824
Query: 863 PSYMYSFLDNEALPLSGDKVPSGILDAKDGLASRIIFGLNAQASVGRMLFNVSPIVSHQL 922
P NE P P G L ++++ + QA + ++SP H L
Sbjct: 825 P--------NEPAPFK----PEGELHE---FGTKLLLHYSPQACKNNICLDLSP--GHGL 867
Query: 923 DKNSFEAAVIGGTQLCSRRL----LQQIIYCVGGVSVLFPLITQFC-KFENEEVGESEK- 976
D +L R+ ++ ++ CVGG+ VL PL+ + + + E G E
Sbjct: 868 DG-----------RLTGHRVETWDVKDVVNCVGGMGVLLPLLERVAVQPQEAEAGPCETH 916
Query: 977 ---GARLTQ-----------------TMRECVTTEVIELIASLLDENLANQQQMHIVSGF 1016
G LT M + ++ + L + NQ+ + G
Sbjct: 917 DLVGPELTSGRNTQGLLLPLGKSSEDRMERNAVAAFLLMLRNFLQNHTVNQESLVQCQGP 976
Query: 1017 SVLGFLLQSVPPRQLNLETLSALKRLFNVVSNSG 1050
+++G LL+ VP +++ L + + L + G
Sbjct: 977 AIIGALLRKVPSSAMDMNVLMSAQLLMEQAAADG 1010