Query: CNT0023163
Subject: sp|Q8GY23|UPL1_ARATH E3 ubiquitin-protein ligase UPL1 OS=Arabidopsis

thaliana GN=UPL2 PE=1 SV=3

 Score = 1176 bits (3042), Expect = 0.0,   Method: Compositional matrix adjust.
Identities = 760/2078 (36%), Positives = 1124/2078 (54%), Gaps = 141/2078 (6%)

Query: 30 TEPPPKIKAFIDRVIKSPLSDIAIPLSGFHWEYNKGNFHHWRPLFLHFDTYFKSYVCCRK 89
+E P KI FI+ V PL I PL+ F WE++KG+FHHW LF HFDT+F+ +V RK
Sbjct: 9 SEVPTKISLFINSVTSVPLELIQEPLASFRWEFDKGDFHHWVDLFYHFDTFFEKHVKVRK 68

Query: 90 DLLLSDNMTGEDALFPKHAVLQILRVMQIILENCHNKSSFSGLE-HFNLLLSSTDPEILL 148
DL + + D FPK AVLQ+LRV++++LENC NK ++ E H +LLL+STD +++
Sbjct: 69 DLRIEEEFDESDPPFPKDAVLQVLRVIRLVLENCTNKQFYTSYEQHLSLLLASTDADVVE 128

Query: 149 ATLQTLASLVRINPSKLHXXXXXXXXXXXXXXXXXXXQGWGSKEEGLGLFSCVVANERNK 208
A LQTLA+ ++ K QGWG KEEGLGL SC
Sbjct: 129 ACLQTLAAFLKRPTGKY-----SIRDASLNLKLFSLAQGWGGKEEGLGLTSCAT------ 177

Query: 209 EEGLCLFPSEAENNSDKTQYRLGSTLHFEFQVPAWQQRDDGTSHASTSLCVIHMEDLNLR 268
E++ D+ +LG TL FEF D+ S L VIH+ D+++R
Sbjct: 178 -----------EHSCDQLFLQLGCTLLFEFYA-----SDESPSELPGGLQVIHVPDVSMR 221

Query: 269 QEDDLAILNQLVDQYNVPQEQRFSLLTRIRYARAFRSVRISRQYSRICLLAFIVLVQSSD 328
E DL +LN+LV +NVP RF+LLTR+R+ARAF S+ +QY+ I L AFIVLVQ+S
Sbjct: 222 SESDLELLNKLVIDHNVPPSLRFALLTRLRFARAFSSLATRQQYTCIRLYAFIVLVQASG 281

Query: 329 AHEELVAFFANEPECTVELINLVRSVHAVPENIRTXXXXXXXXXXXXYSSSHERARXXXX 388
E +V+FF EPE EL+ LV VP IR S +R R
Sbjct: 282 DTENVVSFFNGEPEFVNELVTLVSYEDTVPAKIRILCLQSLVAL------SQDRTRQPTV 335

Query: 389 XXXXXXXXNRMLLLSVLQKAVMSLSSPTDPSSVLFVDAMLHFFLLHVXXXXXXXXXXXXX 448
+R LL ++QKA+ S+ T S+ F +A+L + V
Sbjct: 336 LTAVTSGGHRGLLSGLMQKAIDSVICNTSKWSLAFAEALLSLVTVLVSSSSGCSAMREAG 395

Query: 449 XLVPALLPLLQDNHPGHMHLVCTAVKIIQKLMDYSNVAVTLFRDLGGLEFLIQRLQVELS 508
L+P L+PL++D P H+HLV TAV I++ MDYSN A LFRDLGGL+ I RL+ E+S
Sbjct: 396 -LIPTLVPLIKDTDPQHLHLVSTAVHILEVFMDYSNPAAALFRDLGGLDDTIFRLKQEVS 454

Query: 509 RVID------ASSLNDKSPSIGEALIFDDEML-FSQKRLIKTLLKALGSATYTASNSSRP 561
R D S ++ E L + + ++ + ++ L+K LL+A+ TY N++
Sbjct: 455 RTEDDVKEIVCCSGSNGPEDDTEQLPYSEALISYHRRLLLKALLRAISLGTYAPGNTNL- 513

Query: 562 QSSYETSLPASLSLIFRNAKRFGGDIYASGVTVMSEIIHKDPTCFPILYESGLPNAFLSS 621
S E+ LP L +IFR AK FGG +++ TVMS++IHKDPTCF L +GL +AFL +
Sbjct: 514 YGSEESLLPECLCIIFRRAKDFGGGVFSLAATVMSDLIHKDPTCFNALDSAGLTSAFLDA 573

Query: 622 VTEGILPSSRAVSCVPNGLGAVCLNPKGLEAVKEQNALRFLITIFTSRKYLVALNEGIV- 680
+++ ++ S+ A++C+P L A+CLN GL+AVK++NALR + IF+S YL AL
Sbjct: 574 ISDEVICSAEAITCIPQCLDALCLNNSGLQAVKDRNALRCFVKIFSSPSYLKALTSDTPG 633

Query: 681 PLANAVEELLRHVSSLRGTGVDIIVEILEKLXXXXXXXXXXXXXXXPIDENTA---METD 737
L++ ++ELLRH SSLR GVD+ +EIL + + + A ME D
Sbjct: 634 SLSSGLDELLRHQSSLRTYGVDMFIEILNSILIIGSGMEATTSKSADVPTDAAPVPMEID 693

Query: 738 PEERETDGGMDLVEAMDGTTDGVSCERFVQLCIFHVMVLVHRAVENAETCRLFVEKKGIE 797
+E+ + + D T + E F+ C+ +V L ++NAE C LFVEKKGI+
Sbjct: 694 VDEKSLAVSDEAEPSSD--TSPANIELFLPDCVCNVARLFETVLQNAEVCSLFVEKKGID 751

Query: 798 AIMKLLLRPSIAQSSEGMSIAVHTTAVFKGFTQQHSSTLAQAFCSHLRDHLKQALDGLSP 857
+++L P + S+ S+ + FK F+ QHS+ LA+ CS+LR+HLK+ + L
Sbjct: 752 TVLQLFSLPLMPLST---SLGQSFSVAFKNFSPQHSAGLARILCSYLREHLKKTNNLLVS 808

Query: 858 VAGSFLLAPGISPRKDIFSGLFVIEFLLFLADASRENRWMAALLNEFGNGGKDVLEDIGR 917
+ G+ LL + + I L +E +L L++ + A++++E DVL+++G
Sbjct: 809 IEGTQLLKLESAVQTKILRSLSCLEGMLSLSNFLLKGS--ASVISELSAANADVLKELGI 866

Query: 918 LHREVLWQIALLEDSKVNVKDENXXXXXXXXXXXLENTSTG----DADEPRFSPFRQLLD 973
+++ +WQ+AL D+K +DE ++ST D D R
Sbjct: 867 TYKQTIWQMALCNDTK---EDEKKSVDRASDNSVSASSSTAERESDEDSSNALAVRYTNP 923

Query: 974 PLFRRQRLPSGWSAESQFFDLISLYRDFGRATGFHQRSAGMDXXXXXXXXXXARQLTG-- 1031
R S W +F ++ GR H R A R L
Sbjct: 924 VSIRSSSSQSIWGGHREFLSVVR----SGRGVHGHTRHA----IARMRGGRTRRHLESFN 975

Query: 1032 -----PSEGVTPTGATGDKEKSYHTSCCDMMRSLSFHISHLFSELGKSMLLPSRRRDDSP 1086
P++ + + K+KS +++ L+ + F+ L K +RRR D P
Sbjct: 976 FDSEIPADLPVTSSSHELKKKSTEVLIAEILNKLNCTLRFFFTSLVKGFTSANRRRIDGP 1035

Query: 1087 NVSSSAKSVVSTMATILLDNLNFGGHLDPSKSDSFVSTKCRYLGKVIDFIDAIILD-RPE 1145
++SS++K++ + +A + L+ LNF G+ + D+ +S KCRYLGKV+D I + D R
Sbjct: 1036 SLSSASKTLGTALAKVFLEALNFQGYGAAAGPDTSLSLKCRYLGKVVDDITFLTFDTRRR 1095

Query: 1146 SCNPILVNCFYVRGVIHVILTTFEATSQLLFTVIRPPTSPMETEDGNPRQDGRDDTDHS- 1204
C +VN FYV G +LTTFEATSQLL+ V P S + N + R+ HS
Sbjct: 1096 VCFTAMVNSFYVHGTFKELLTTFEATSQLLWKV---PFSIRASSTENEKSGERNLWSHSK 1152

Query: 1205 WIYGPLASYTLLMDHLVTSSFIYSPFTK-HLLCQP----LISGNVAIPRDAEAFVRVLQS 1259
W+ L +Y +D+ V S+++ SP ++ LL QP L G +PR+ E FVR LQS
Sbjct: 1153 WLVDTLQNYCRALDYFVNSTYLLSPTSQTQLLVQPASVDLSIGLFPVPREPETFVRNLQS 1212

Query: 1260 KVLKAILPIWNHPQFSECNLEFVSSIFSIIRHVYSGVDVKSVNSS-----TAGRLAGPPP 1314
+VL+ ILPIWNHP F +CN FV+S+ S++ H+YSGV N S T R P
Sbjct: 1213 QVLEVILPIWNHPMFPDCNPNFVASVTSLVTHIYSGVVDTRENRSGATQGTNQRALPLQP 1272

Query: 1315 DESTISVIVEMGFSRSRAEEALRQVGTNSVEMAMEWLFSHPEE-AQEDDELARALAMSLG 1373
DE+ + +IVEMGFSRSRAE+ALR+VGTNSVEMAM+WLF++PE+ QEDDELA+ALA+SLG
Sbjct: 1273 DEAIVGMIVEMGFSRSRAEDALRRVGTNSVEMAMDWLFTNPEDPVQEDDELAQALALSLG 1332

Query: 1374 NSGSSGKEDAVANTGTXXXXXXXXXXXXIDDLLMTCVRLLQLKDSLTFSVRDLLVMMCSR 1433
NS + K + +D+++ V+L Q DS+ F + DL V +C+R
Sbjct: 1333 NSSETPKLEDTEKPVDVPQEEAEPKEPPVDEVIAASVKLFQSDDSIAFPLVDLFVTLCNR 1392

Query: 1434 NDGNCRPKVVTFVIDHIKLS----SGNTTLLSALFHVLALVLHEDTASREVAAKHGLTGI 1489
N G RPK+V ++I +KL S +T L+ + H+LALVL ED +RE+AA+ G+ +
Sbjct: 1393 NKGEDRPKIVFYLIQQLKLVQLDFSKDTGALTMIPHILALVLSEDDNTREIAAQDGIVAV 1452

Query: 1490 ALNLLAQWHPSSLDGDKTHVPKWVTASLLAIDEMLQVDPKPSSE-----------ISDQS 1538
A+ +L ++ S PK ++A LL + MLQ + SSE +SD
Sbjct: 1453 AIGILTDFNLKSESETDILAPKCISALLLVLSMMLQAQTRLSSEYVEGNQGGSLVLSDSP 1512

Query: 1539 RKDETKTENSLVND--ENASSNKLQTSLGLTARHTTLPEQKRLIEIACGFIRDQLPSETM 1596
+ +++L +D + S+ L++ G + + T+ E +++ IACG I+ ++P+ M
Sbjct: 1513 QDSTAALKDALSSDVAKGESNQALESMFGKSTGYLTMEESSKVLLIACGLIKQRVPAMIM 1572

Query: 1597 HVVLQLCATLTRVHAVSVTFLEAGGLHSLLSLPTVSLFSGFDNVAATIVRHILEDPHTLQ 1656
VLQLCA LT+ HA+++ FLE GGL SL +LP F G+D VA+ IVRH++EDP TLQ
Sbjct: 1573 QAVLQLCARLTKSHALAIQFLENGGLSSLFNLPKKCFFPGYDTVASVIVRHLVEDPQTLQ 1632

Query: 1657 QAMESEIRHSLVAALNRNSNGRVTPRNFLTGLASVITRDPAVFMLAAQSVCQIEMVGERP 1716
AME+EIR +L + GRV PR FLT +A VI+RDP VFM A S CQ+E G
Sbjct: 1633 IAMETEIRQTLSG---KRHIGRVLPRTFLTTMAPVISRDPVVFMKAVASTCQLESSGGTD 1689

Query: 1717 YVVLLXXXXXXXXXXXXXXXXXXXNLQSLEGKSPTGDTPSKASDTSVKSSKAHRKSPQSF 1776
+V+L P G + +K D S K SK+HR+ P +F
Sbjct: 1690 FVILTKEKEKPKVSGSE---------HGFSLNEPLGISENKLHDGSGKCSKSHRRVPTNF 1740

Query: 1777 ITVIELLLDSIVAFVPSLKDVSQTDGASSSVDMEIDEXXXXXXXXXXXXXPCEDKSDSNQ 1836
I VI+ L+D +++F P LK Q A++ + M++DE P +K++
Sbjct: 1741 IQVIDQLIDIVLSF-PGLK--RQEGEAANLISMDVDEPTTKVKGKSKVGEP--EKAELGS 1795

Query: 1837 EASASLAKNVFILKLLTEILLTYSSSVHVLLRRDAEISCSRGGPQRGSSATGIRGVFYHV 1896
E S LA+ FILKLL++I+L Y V+LRRD EIS RG S G G+ YHV
Sbjct: 1796 EKSEELARVTFILKLLSDIVLMYLHGTSVILRRDTEISQLRGSNLPDDSP-GNGGLIYHV 1854

Query: 1897 LHKLLPSPGNQKKDKKSDGDWRQKLATRSSQFLLXXXXXXXXXXXXXFSEISNVFNDF-- 1954
+H+LLP + + +W++KL+ ++S FL+ +E++ V + F
Sbjct: 1855 IHRLLPISLEKFVGPE---EWKEKLSEKASWFLVVLCSRSNEGRKRIINELTRVLSVFAS 1911

Query: 1955 VGSSGSDEFRAPDCKMQSFIDLINEILAARSPTGSY----ISAEVAATFSEVGLVRSLTR 2010
+G S S PD ++ +F +L+ IL S + ++ S +VA + + G ++ LT
Sbjct: 1912 LGRSSSQSVLLPDKRVLAFANLVYSILTKNSSSSNFPGCGCSPDVAKSMIDGGTIQCLTS 1971

Query: 2011 TLQILDLDHPDSPKLVTAIVKALEAVTK-----EQVQS 2043
L ++DLDHPD+PKLVT I+K+LE +T+ EQ++S
Sbjct: 1972 ILNVIDLDHPDAPKLVTLILKSLETLTRAANAAEQLKS 2009



Score = 1068 bits (2763), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 605/1108 (54%), Positives = 727/1108 (65%), Gaps = 56/1108 (5%)

Query: 2588 ESASIDPAFLDALPEELRAEVLSAQQNQVAQPPAEQPQTNGDIDPEFLAALPPDIRAEVX 2647
E +IDP FL+ALPE+LRAEVL++QQ Q QPP +P + DIDPEFLAALPP+I+ EV
Sbjct: 2589 EVNAIDPTFLEALPEDLRAEVLASQQAQSVQPPTYEPPSVDDIDPEFLAALPPEIQREVL 2648

Query: 2648 XXXXXXXXXXXXELEGQPVEMDTVSIIATFPSDLREEVLLTSSDAILANLTPALVAEANM 2707
+ GQPV+MD SIIAT P+DLREEVLLTSS+A+LA L P L+AEA M
Sbjct: 2649 AQQRAQRMLQQSQ--GQPVDMDNASIIATLPADLREEVLLTSSEAVLAALPPPLLAEAQM 2706

Query: 2708 LRERFAHRYHGGT-LFGMFPR-NRRGESSGRGDTGPSSLDRG-GI------VSRRSNGSK 2758
LR+R Y + +FG R N R G TG ++RG G+ VS ++G K
Sbjct: 2707 LRDRAMRHYQARSRVFGSSHRLNNRRNGLGYRLTG---MERGVGVTIGQRDVSSSADGLK 2763

Query: 2759 LVEADGAPLVDTDALKAMIRLLRVVQPLYKGQLQRLLLNLCAHRETRTALVQXXXXXXXX 2818
+ E +G PLV+ DALK++IRLLR+ QPL KG LQRLLLNLCAH TR LVQ
Sbjct: 2764 VKEIEGDPLVNADALKSLIRLLRLAQPLGKGLLQRLLLNLCAHSFTRANLVQLLLDMIRP 2823

Query: 2819 XERGMGSTSTYAGEPSYRLYACPNNVIYSRPQFLDGVPPLVSRRVLEVLIYLARNHPYVA 2878
+ S A RLY C NV+Y R Q L+G+PPLV RRVLEVL YLA NH VA
Sbjct: 2824 EMETL--PSELALTNPQRLYGCQLNVVYGRSQLLNGLPPLVFRRVLEVLTYLATNHSAVA 2881

Query: 2879 XXXXXXXXXXXXXXXXXXXDQARGKAVMILDDDQEEMKLKGDVSIVXXXXXXNQPLYSRS 2938
+GK + + D ++ ++ +V N+P +S
Sbjct: 2882 DMLFYFDSSLLSQLSSR-----KGKEKVTHETDSRDL----EIPLVVFLKLLNRPQLLQS 2932

Query: 2939 VAHLEQLLNLLEVIMDNAESESNLSNKSGGSQLEQPSASQSALPDSQANASNVGSSSTEE 2998
+HL ++ LL+V++ A S++E S S S +P+ N VG ++ E
Sbjct: 2933 TSHLALVMGLLQVVVYTA-----------ASRIEGWSPS-SGVPEKLENKP-VGEEASSE 2979

Query: 2999 VKPIETDEDSRPSASGTSDENNVSAVLCDXXXXXXXXXXXXXXXXXXXDNAYVLIAEVIK 3058
+ D +S S + + + + D Y L EV+K
Sbjct: 2980 T---QKDAESELSVARRKNCAELYNIFLQLPQSDLCNLCMLLGYEGLSDKIYSLAGEVLK 3036

Query: 3059 KLVAIASTHCRLFISELADSIQSLSQSAITELRSYGEAEDMLLSTSSTDGTAILRVLQAX 3118
KL A+ TH + F EL++ LS S + L + + M +T S G +ILRVLQ
Sbjct: 3037 KLAAVDVTHRKFFTKELSELASGLSSSTVRVLATLSTTQKMSQNTCSMAGASILRVLQVL 3096

Query: 3119 XXXXXXXXEREKEAQVLSEREQNDPIMQVWDLNAALEPLWQELXXXXXXXXXXXXXXXXX 3178
+ +++E+ + IMQ L ALEPLWQEL
Sbjct: 3097 SSLTSTIDDSNVGTDKETDQEEQN-IMQ--GLKVALEPLWQELGQCISMTELQLDHTAAT 3153

Query: 3179 XXXX--XXXXXXXXXXXXXAGTQNILPYIESFFVTCEKL-GPGQLGPGYDFANVSTPEAE 3235
GTQ++LP IE+FFV CEK+ P L A V+ E +
Sbjct: 3154 SNVNPGDHVLGISPTSSLSPGTQSLLPLIEAFFVLCEKIQTPSMLQQD---ATVTAGEVK 3210

Query: 3236 DASQKSSASHSKVD-----DKHGAFVKFSEKHRKLLNSFIRQNPGLLEKSFSIMLKVPRF 3290
++S S+S + VD D F KF EKHR+LLNSF+RQNP LLEKSFS+MLK PR
Sbjct: 3211 ESSTHGSSSKTIVDSQKKIDGSVTFSKFVEKHRRLLNSFVRQNPSLLEKSFSMMLKAPRL 3270

Query: 3291 IDFDNKRAHFRSKIKHQHDHHHS-PLRISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQ 3349
IDFDNK+A+FRS+I+HQHD H S PLRISVRRAY+LEDSYNQLRMRS QDLKGRL V FQ
Sbjct: 3271 IDFDNKKAYFRSRIRHQHDQHISGPLRISVRRAYVLEDSYNQLRMRSPQDLKGRLNVQFQ 3330

Query: 3350 GEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNESTFQPNPNSVFQTEHLSYFKFVGR 3409
GEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGN++TFQPNPNSV+QTEHLSYFKFVGR
Sbjct: 3331 GEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDATFQPNPNSVYQTEHLSYFKFVGR 3390

Query: 3410 VVAKALFDGQLLDVHFTRSFYKHILGAKVTYHDIEAIDPDFFKNLKWMLENDTSDILDLT 3469
+VAKALFDGQLLDV+FTRSFYKHILG KVTYHDIEA+DPD++KNLKW+LEND SDILDLT
Sbjct: 3391 MVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLLENDVSDILDLT 3450

Query: 3470 FSVDADEEKLILYERTEVTDYELIPGGRNVRVTEENKHEYVDLVAEHKLTTAIRPQINAF 3529
FS+DADEEK ILYE+TEVTDYEL PGGRN+RVTEE KHEYVDLVA+H LT+AIRPQINAF
Sbjct: 3451 FSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVADHILTSAIRPQINAF 3510

Query: 3530 MEGFNELIPRELISIFHDKELELLISGLPDIDLDDLRANTEYSGYSAASPVIQWFWEVVN 3589
+EG NELIPREL+SIF+DKELELLISGLP+ID DDL+ANTEY+ Y+ SPVI+WFWEVV
Sbjct: 3511 LEGLNELIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTSYTVGSPVIRWFWEVVK 3570

Query: 3590 GFSKEDKARLLQFVTGTSKVPLEGFRALQGISGSQRFQIHKAYGSPDHLPSAHTCFNQLD 3649
FSKED AR LQFVTGTSKVPLEGF+ALQGISG QR QIHKAYGSP+ LPSAHTCFNQLD
Sbjct: 3571 AFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGSPERLPSAHTCFNQLD 3630

Query: 3650 LPEYPTKQQLQERLLLAIHEGNEGFGFG 3677
LPEY +K+Q+QERLLLAIHE NEGFGF
Sbjct: 3631 LPEYQSKEQVQERLLLAIHEANEGFGFA 3658

Query: CNT0023163
Subject: sp|Q9P4Z1|TOM1_NEUCR E3 ubiquitin-protein ligase TOM1-like

thaliana GN=UPL1 PE=1 SV=3

 Score = 1176 bits (3041), Expect = 0.0,   Method: Compositional matrix adjust.
Identities = 787/2174 (36%), Positives = 1161/2174 (53%), Gaps = 178/2174 (8%)

Query: 30 TEPPPKIKAFIDRVIKSPLSDIAIPLSGFHWEYNKGNFHHWRPLFLHFDTYFKSYVCCRK 89
+E P KIK+FI+ V PL I PL+ F WE++KG+FHHW LF +FDT+F+ +V RK
Sbjct: 9 SEVPSKIKSFINSVTSVPLELIHEPLACFRWEFDKGDFHHWVDLFNYFDTFFEKHVQVRK 68

Query: 90 DLLLSDNMTGEDALFPKHAVLQILRVMQIILENCHNKSSFSGLE-HFNLLLSSTDPEILL 148
DL + +N D FPK AVLQ+LRV++++LENC NK +S E H +LLL+STD +++
Sbjct: 69 DLHIEENFEESDPPFPKDAVLQVLRVIRVVLENCTNKHFYSSYEQHLSLLLASTDADVVE 128

Query: 149 ATLQTLASLVRINPSKLHXXXXXXXXXXXXXXXXXXXQGWGSKEEGLGLFSCVVANERNK 208
A LQTLA+ ++ K QGWG KEEGLGL SC
Sbjct: 129 ACLQTLAAFLKRQIGKY-----SIRDASLNSKLFSLAQGWGGKEEGLGLTSCA------- 176

Query: 209 EEGLCLFPSEAENNSDKTQYRLGSTLHFEFQVPAWQQRDDGTSHASTSLCVIHMEDLNLR 268
AEN+ D+ +LG TLHFEF P+ D+ S L VIH+ D+++
Sbjct: 177 ----------AENSCDQVSLQLGRTLHFEF-YPS----DESPSELPGGLQVIHVPDVSIC 221

Query: 269 QEDDLAILNQLVDQYNVPQEQRFSLLTRIRYARAFRSVRISRQYSRICLLAFIVLVQSSD 328
E DL +LN+LV +NVP RF+LLTR+R+ARAF S+ +Q++ I L AF+VLVQ+S
Sbjct: 222 AESDLELLNKLVIDHNVPPSLRFALLTRMRFARAFSSLATRQQFTCIRLYAFVVLVQASG 281

Query: 329 AHEELVAFFANEPECTVELINLVRSVHAVPENIRTXXXXXXXXXXXXYSSSHERARXXXX 388
E +V+FF EPE EL+ LV VPE IR S +R R
Sbjct: 282 DTENVVSFFNGEPEFVNELVTLVSYEDTVPEKIRILCLLSLVAL------SQDRTRQPTV 335

Query: 389 XXXXXXXXNRMLLLSVLQKAVMSLSSPTDPSSVLFVDAMLHFFLLHVXXXXXXXXXXXXX 448
+R LL ++QKA+ S+ T S+ F +A+L + V
Sbjct: 336 LTAVTSGGHRGLLSGLMQKAIDSVVCITSKWSLAFAEALLSLVTVLVSSSSGCSAMREAG 395

Query: 449 XLVPALLPLLQDNHPGHMHLVCTAVKIIQKLMDYSNVAVTLFRDLGGLEFLIQRLQVELS 508
L+P L+PL++D P H+HLV AV I++ MDYSN A LFRDLGGL+ I RL++E+S
Sbjct: 396 -LIPTLVPLIKDTDPQHLHLVSAAVHILEAFMDYSNPAAALFRDLGGLDDTIFRLKLEVS 454

Query: 509 RV-IDASSLNDKSPSIG---EALIFDDEML-FSQKRLIKTLLKALGSATYTASNSSRPQS 563
R D N S S G E L + + ++ + ++ L+K LL+A+ TY N++
Sbjct: 455 RTEDDVKEKNCSSDSNGPDTEQLPYSEALISYHRRLLLKALLRAISLGTYAPGNTNL-YG 513

Query: 564 SYETSLPASLSLIFRNAKRFGGDIYASGVTVMSEIIHKDPTCFPILYESGLPNAFLSSVT 623
S E+ LP L +IFR AK FGG +++ TVMS++IHKDPTCF L +GL + FL +++
Sbjct: 514 SEESLLPECLCIIFRRAKDFGGGVFSLAATVMSDLIHKDPTCFNALDSAGLTSTFLDAIS 573

Query: 624 EGILPSSRAVSCVPNGLGAVCLNPKGLEAVKEQNALRFLITIFTSRKYLVALNEGIVP-- 681
+ ++ S+ A++C+P L A+CLN GL+AVK++NALR + IFTS YL AL G P
Sbjct: 574 DEVICSAEAITCIPQCLDALCLNNSGLQAVKDRNALRCFVKIFTSPSYLRALT-GDTPGS 632

Query: 682 LANAVEELLRHVSSLRGTGVDIIVEILEKLXXXXXXXXXXXXXXXPIDENTA---METDP 738
L++ ++ELLRH SSLR GVD+ +EIL + + + A ME D
Sbjct: 633 LSSGLDELLRHQSSLRTYGVDMFIEILNSMLIIGSGMEATTSKSADVPTSAAPVPMEIDV 692

Query: 739 EERETDGGMDLVEAMDGTTDGVSCERFVQLCIFHVMVLVHRAVENAETCRLFVEKKGIEA 798
+E+ + + D T + E F+ C+ +V L ++NAE C LFVEKKGI+A
Sbjct: 693 DEKSLAVSDEAEPSSD--TSPANIELFLPDCVCNVARLFETVLQNAEVCSLFVEKKGIDA 750

Query: 799 IMKLLLRPSIAQSSE-GMSIAVHTTAVFKGFTQQHSSTLAQAFCSHLRDHLKQALDGLSP 857
+++L P + S+ G S +V FK F+ QHS+ LA+ CS+LR+HLK+ L
Sbjct: 751 VLQLFSLPLMPLSTSLGQSFSV----AFKNFSPQHSAGLARIVCSYLREHLKKTKILLVS 806

Query: 858 VAGSFLLAPGISPRKDIFSGLFVIEFLLFLADASRENRWMAALLNEFGNGGKDVLEDIGR 917
+ G+ LL + + I L +E +L L++ + A++++E DVL+++G
Sbjct: 807 IEGTQLLKLESAIQTKILRSLSCLEGMLSLSNFLLKGS--ASVISELSAADADVLKELGI 864

Query: 918 LHREVLWQIALLEDSKVNVK---DENXXXXXXXXXXXLENTSTGDADEPRFSPFRQLLDP 974
+++ +WQ+AL D+K + K D E S D D R
Sbjct: 865 TYKQTIWQMALCNDTKEDEKKSVDRGSDNSVSASSSTAERES--DEDSSNALAVRYTNPV 922

Query: 975 LFRRQRLPSGWSAESQFFDLI------------SLYRDFGRATGFHQRSAGMDXXXXXXX 1022
R S W + +F ++ ++ R G T H S D
Sbjct: 923 SIRSSSSQSIWGGDREFLSIVRSGEGIHGRTRHAIARMRGGRTRRHLESFNFDSEI---- 978

Query: 1023 XXXARQLTGPSEGVTPTGATGDKEKSYHTSCCDMMRSLSFHISHLFSELGKSMLLPSRRR 1082
P++ + + K+KS +++ L+ + F+ L K +RRR
Sbjct: 979 ---------PADLPVTSSSHELKKKSTEVLIAEILNKLNCTLRFFFTALVKGFTSANRRR 1029

Query: 1083 DDSPNVSSSAKSVVSTMATILLDNLNFGGHLDPSKSDSFVSTKCRYLGKVIDFIDAIILD 1142
D ++SS++K++ + +A + L+ LNF G+ + + +S KCRYLGKV+D I + D
Sbjct: 1030 IDGASLSSASKTLGTALAKVFLEALNFDGYGAAAGHEKSLSVKCRYLGKVVDDITFLSFD 1089

Query: 1143 -RPESCNPILVNCFYVRGVIHVILTTFEATSQLLFTVIRPPTSPMETEDGNPRQDGRDDT 1201
R C +VN FYV G +LTTFEATSQLL+TV P S + N + R+
Sbjct: 1090 TRRRVCFTAMVNSFYVHGTFKELLTTFEATSQLLWTV---PFSIPASSTENEKPGERNIW 1146

Query: 1202 DHS-WIYGPLASYTLLMDHLVTSSFIYSPFTK-HLLCQP----LISGNVAIPRDAEAFVR 1255
HS W+ L +Y +D+ V S+++ SP ++ LL QP L G +PR+ E FVR
Sbjct: 1147 SHSKWLVDTLQNYCRALDYFVNSTYLLSPTSQTQLLVQPASVGLSIGLFPVPREPETFVR 1206

Query: 1256 VLQSKVLKAILPIWNHPQFSECNLEFVSSIFSIIRHVYSGVDVKSVNSSTAGR----LAG 1311
LQS+VL ILPIWNHP F +CN FV+S+ S++ H+YSGV N S R A
Sbjct: 1207 NLQSQVLDVILPIWNHPMFPDCNPNFVASVTSLVTHIYSGVVDARENRSGVTRGINQRAL 1266

Query: 1312 P-PPDESTISVIVEMGFSRSRAEEALRQVGTNSVEMAMEWLFSHPEE-AQEDDELARALA 1369
P DES + +IVEMGFSRSRAE ALR+VGTNSVEMAM+WLF++PE+ QEDDELA+ALA
Sbjct: 1267 PLQLDESIVGMIVEMGFSRSRAEIALRRVGTNSVEMAMDWLFTNPEQPVQEDDELAQALA 1326

Query: 1370 MSLGNSGSSGKEDAVANTGTXXXXXXXXXXXXIDDLLMTCVRLLQLKDSLTFSVRDLLVM 1429
+SLGNS + K + +D+++ V+L Q DS+ F + DL V
Sbjct: 1327 LSLGNSSETPKLEDTEKPVDVPQEEAEPKEPPVDEVIAASVKLFQSDDSMAFPLMDLFVT 1386

Query: 1430 MCSRNDGNCRPKVVTFVIDHIKLS----SGNTTLLSALFHVLALVLHEDTASREVAAKHG 1485
+C+RN G RPK+V+++I +KL S +T L+ + H+LALVL ED +RE+AA+ G
Sbjct: 1387 LCNRNKGEDRPKIVSYLIQQLKLVQLDFSKDTGALTMIPHILALVLSEDDNTREIAAQDG 1446

Query: 1486 LTGIALNLLAQWHPSSLDGDKTHVPKWVTASLLAIDEMLQVDPKPSSEI----------- 1534
+ +A+ +L ++ S + PK ++A LL + MLQ K SSE
Sbjct: 1447 IVTVAIGILTDFNLKSESETEILAPKCISALLLVLSMMLQAQTKLSSEYVEGNQGGSLVP 1506

Query: 1535 SDQSRKDETKTENSLVND--ENASSNKLQTSLGLTARHTTLPEQKRLIEIACGFIRDQLP 1592
SD + +++L +D + S+ L+ G + + T+ E + + IACG I+ +P
Sbjct: 1507 SDSPQDSTAALKDALSSDVAKGESNQALELIFGKSTGYLTMEEGHKALLIACGLIKQHVP 1566

Query: 1593 SETMHVVLQLCATLTRVHAVSVTFLEAGGLHSLLSLPTVSLFSGFDNVAATIVRHILEDP 1652
+ M VLQLCA LT+ HA+++ FLE GGL SL +LP F G+D VA+ IVRH++EDP
Sbjct: 1567 AMIMQAVLQLCARLTKSHALAIQFLENGGLSSLFNLPKKCCFPGYDTVASVIVRHLVEDP 1626

Query: 1653 HTLQQAMESEIRHSLVAALNRNSNGRVTPRNFLTGLASVITRDPAVFMLAAQSVCQIEMV 1712
TLQ AME+EIR +L + GRV PR FLT +A VI+RDP VFM A S CQ+E
Sbjct: 1627 QTLQIAMETEIRQTLSG---KRHIGRVLPRTFLTTMAPVISRDPVVFMKAVASTCQLESS 1683

Query: 1713 GERPYVVLLXXXXXXXXXXXXXXXXXXXNLQSLEGKSPTGDTPSKASDTSVKSSKAHRKS 1772
G R +V+L + P G + +K D S K SK+HR+
Sbjct: 1684 GGRDFVIL---------SKEKEKPKVSGSEHGFSLNEPLGISENKLHDVSGKCSKSHRRV 1734

Query: 1773 PQSFITVIELLLDSIVAFVPSLKDVSQTDGASSSVDMEIDEXXXXXXXXXXXXXPCEDKS 1832
P +FI VI+ L+D +++F P +K Q DG ++ + ME+DE P +K+
Sbjct: 1735 PANFIQVIDQLIDLVLSF-PRVK--RQEDGETNLISMEVDEPTTKVKGKSKVGEP--EKA 1789

Query: 1833 DSNQ----------EASASLAKNVFILKLLTEILLTYSSSVHVLLRRDAEISCSRGGPQR 1882
S++ E S LA+ FILKLL++I+L YS V+LRRD EIS RG
Sbjct: 1790 SSSRVGEPEKAEIPEKSEELARVTFILKLLSDIVLMYSHGTSVILRRDTEISQLRGS-NL 1848

Query: 1883 GSSATGIRGVFYHVLHKLLPSPGNQKKDKKSDGDWRQKLATRSSQFLLXXXXXXXXXXXX 1942
+ G G+ YHV+H+LLP + + +W++KL+ ++S FL+
Sbjct: 1849 PDDSPGNGGLIYHVIHRLLPISLEKFVGPE---EWKEKLSEKASWFLVVLCSRSNEGRKR 1905

Query: 1943 XFSEISNVFNDF--VGSSGSDEFRAPDCKMQSFIDLINEILAARSPT------GSYISAE 1994
+E+S V + F +G S S PD ++ +F +L+ IL S + G S +
Sbjct: 1906 IINELSRVLSVFASLGRSSSKSVLLPDKRVLAFANLVYSILTKNSSSSSSNFPGCGCSPD 1965

Query: 1995 VAATFSEVGLVRSLTRTLQILDLDHPDSPKLVTAIVKALEAVTK-----EQVQSA----- 2044
VA + + G ++ LT L ++DLDHPD+PKLVT I+K+LE +T+ EQ++S
Sbjct: 1966 VAKSMMDGGTIQCLTSILHVIDLDHPDAPKLVTLILKSLETLTRAANAAEQLKSEVPNEK 2025

Query: 2045 ---------DSHSAKVDTPTNP-GSNSEELRGSENGNGVGQTSEPPAQPASNQMATEQLE 2094
DSH +T + N+ L+ + G GQ + ++ + + Q +
Sbjct: 2026 KNRDSDERHDSHGNSTETEADELNQNNSSLQQVTDAAGNGQEQAQVSSQSAGERGSSQTQ 2085

Query: 2095 SFGGALTSGGSDSV 2108
+ + G +++
Sbjct: 2086 AMPQDMRIEGDETI 2099



Score = 1065 bits (2754), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 611/1111 (54%), Positives = 726/1111 (65%), Gaps = 55/1111 (4%)

Query: 2588 ESASIDPAFLDALPEELRAEVLSAQQNQVAQPPAEQPQTNGDIDPEFLAALPPDIRAEVX 2647
E +IDP FL+ALPE+LRAEVL++QQ Q QPP +P DIDPEFLAALPPDI+ EV
Sbjct: 2605 EVNAIDPTFLEALPEDLRAEVLASQQAQSVQPPTYEPPPVDDIDPEFLAALPPDIQTEVL 2664

Query: 2648 XXXXXXXXXXXXELEGQPVEMDTVSIIATFPSDLREEVLLTSSDAILANLTPALVAEANM 2707
+ +GQ V+MD SIIAT P+DLREEVLLTSS+A+LA L L+AEA M
Sbjct: 2665 AQQRAQRMVQ--QSQGQAVDMDNASIIATLPADLREEVLLTSSEAVLAALPSPLLAEAQM 2722

Query: 2708 LRERFAHRYHG-GTLFGMFPR--NRRGESSGRGDTGPSSLDRG-GI------VSRRSNGS 2757
LR+R Y ++FG R NRR +G G + +DRG G+ VS ++G
Sbjct: 2723 LRDRAMSHYQARSSVFGSSHRLNNRR---NGLGYNRLTGMDRGVGVTIGQRAVSSSADGL 2779

Query: 2758 KLVEADGAPLVDTDALKAMIRLLRVVQPLYKGQLQRLLLNLCAHRETRTALVQXXXXXXX 2817
K+ E +G PLV+ DALK++IRLLR+ QPL KG LQRLLLNLCAH TR LVQ
Sbjct: 2780 KVKEIEGDPLVNADALKSLIRLLRLAQPLGKGLLQRLLLNLCAHSFTRANLVQLLLDMIR 2839

Query: 2818 XXERGMGSTSTYAGEPSYRLYACPNNVIYSRPQFLDGVPPLVSRRVLEVLIYLARNHPYV 2877
S S A RLY C +NV+Y R Q L+G+PPLV RRVLEVL YLA NH V
Sbjct: 2840 PEMET--SPSELAITNPQRLYGCQSNVVYGRSQLLNGLPPLVFRRVLEVLTYLATNHSAV 2897

Query: 2878 AXXXXXXXXXXXXXXXXXXXDQARGKAVMILDDDQEEMKLKGDVSIVXXXXXXNQPLYSR 2937
A +GK + D ++ ++ +V N+P +
Sbjct: 2898 ADMLFYFDSSLLSQLSSR-----KGKEKVTHVTDSRDL----EIPLVVFLKLLNRPQLLQ 2948

Query: 2938 SVAHLEQLLNLLEVIMDNAESESNLSNKSGGSQLEQPSASQSALPDSQANASNVGSSSTE 2997
S +HL ++ LL+V++ A S++E S S S +P+ N +S+E
Sbjct: 2949 STSHLGLVMGLLQVVVYTA-----------ASRIEGWSPS-SGVPEKLENKPVGEEASSE 2996

Query: 2998 EVKPIETDEDSRPSASGTSDEN--NVSAVLCDXXXXXXXXXXXXXXXXXXXDNAYVLIAE 3055
K E++ S +N + + D Y L E
Sbjct: 2997 TRKDAESELVGEADLSVARRKNCAEIYNIFLQLPQSDLCNLCILLGYEGLSDKIYSLAGE 3056

Query: 3056 VIKKLVAIASTHCRLFISELADSIQSLSQSAITELRSYGEAEDMLLSTSSTDGTAILRVL 3115
V+KKL A+ H + F EL++ SLS S + EL + + M ST S G +ILRVL
Sbjct: 3057 VLKKLAAVDVAHRKFFTKELSELASSLSSSTVRELATLSSKQKMSRSTGSMAGASILRVL 3116

Query: 3116 QAXXXXXXXXXEREKEAQVLSEREQNDPIMQVWDLNAALEPLWQELXXXXXXXXXXXXXX 3175
Q E + +E+E+ + IMQ LN ALEPLW EL
Sbjct: 3117 QVLSSLTSPIDESNVGTERETEQEEQN-IMQ--RLNVALEPLWHELSQCISMTELQLDHT 3173

Query: 3176 XXXXXXX--XXXXXXXXXXXXXAGTQNILPYIESFFVTCEKL-GPGQLGPGYDFANVSTP 3232
GTQ +LP IE+FFV CEK+ P L NV+
Sbjct: 3174 AAASNINPGDHVLGISPTSSLSPGTQRLLPLIEAFFVLCEKIQTPSMLQQD---TNVTAG 3230

Query: 3233 EAEDASQKSSASHSKVD-----DKHGAFVKFSEKHRKLLNSFIRQNPGLLEKSFSIMLKV 3287
E +++S S+S + VD D F KF+EKHR+LLNSFIRQNP LLEKS S+MLK
Sbjct: 3231 EVKESSAHGSSSKTSVDSQKKTDGSVTFSKFAEKHRRLLNSFIRQNPSLLEKSLSMMLKA 3290

Query: 3288 PRFIDFDNKRAHFRSKIKHQHDHHHS-PLRISVRRAYILEDSYNQLRMRSTQDLKGRLTV 3346
PR IDFDNK+A+FRS+I+HQHD H S PLRISVRRAY+LEDSYNQLRMRS QDLKGRL V
Sbjct: 3291 PRLIDFDNKKAYFRSRIRHQHDQHISGPLRISVRRAYVLEDSYNQLRMRSPQDLKGRLNV 3350

Query: 3347 HFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNESTFQPNPNSVFQTEHLSYFKF 3406
FQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGN++TFQPNPNSV+QTEHLSYFKF
Sbjct: 3351 QFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDATFQPNPNSVYQTEHLSYFKF 3410

Query: 3407 VGRVVAKALFDGQLLDVHFTRSFYKHILGAKVTYHDIEAIDPDFFKNLKWMLENDTSDIL 3466
VGR+VAKALFDGQLLDV+FTRSFYKHILG KVTYHDIEA+DPD++KNLKW+LEND SDIL
Sbjct: 3411 VGRMVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLLENDVSDIL 3470

Query: 3467 DLTFSVDADEEKLILYERTEVTDYELIPGGRNVRVTEENKHEYVDLVAEHKLTTAIRPQI 3526
DLTFS+DADEEK ILYE+TEVTDYEL PGGRN+RVTEE KHEYVDLVA H LT AIRPQI
Sbjct: 3471 DLTFSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVAGHILTNAIRPQI 3530

Query: 3527 NAFMEGFNELIPRELISIFHDKELELLISGLPDIDLDDLRANTEYSGYSAASPVIQWFWE 3586
NAF+EGFNELIPREL+SIF+DKELELLISGLP+ID DDL+ANTEY+ Y+A SPVI WFWE
Sbjct: 3531 NAFLEGFNELIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTSYTAGSPVIHWFWE 3590

Query: 3587 VVNGFSKEDKARLLQFVTGTSKVPLEGFRALQGISGSQRFQIHKAYGSPDHLPSAHTCFN 3646
VV FSKED AR LQFVTGTSKVPLEGF+ALQGISG QR QIHKAYG+P+ LPSAHTCFN
Sbjct: 3591 VVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGAPERLPSAHTCFN 3650

Query: 3647 QLDLPEYPTKQQLQERLLLAIHEGNEGFGFG 3677
QLDLPEY +K+QLQERLLLAIHE +EGFGF
Sbjct: 3651 QLDLPEYQSKEQLQERLLLAIHEASEGFGFA 3681

Query: CNT0023163
Subject: sp|O13834|PTR1_SCHPO E3 ubiquitin-protein ligase ptr1

OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A /
CBS 708.71 / DSM 1257 / FGSC 987) GN=B11B22.010 PE=3 SV=4

 Score =  498 bits (1281), Expect = e-139,   Method: Compositional matrix adjust.
Identities = 240/488 (49%), Positives = 331/488 (67%), Gaps = 32/488 (6%)

Query: 3201 ILPYIESFFVTCEKLGPGQLGPGYDFANVSTPEAEDASQKSS------ASHSKVDDKHGA 3254
+LP IES V C+ N + +A S +S S D G
Sbjct: 3610 LLPLIESLMVVCK--------------NTTLSDASAVSNANSQKEMLLTSPPPEDRIAGL 3655

Query: 3255 FVKFSEKHRKLLNSFIRQNPGLLEKSFSIMLKVPRFIDFDNKRAHFRSKI--KHQHDHH- 3311
F F+E+HR++LN +R NP L+ +FS+++K P+ ++FDNKR +F + K+Q H
Sbjct: 3656 FFTFTEEHRRILNELVRHNPKLMSGTFSLLVKNPKVLEFDNKRNYFNRSVHSKYQQTRHS 3715

Query: 3312 HSPLRISVRRAYILEDSYNQLRMRSTQDLK-GRLTVHFQGEEGIDAGGLTREWYQLLSRV 3370
PL++ VRR ++ DS+ L + +LK G+L + FQGEEG+DAGG+TREW+Q+LSR
Sbjct: 3716 FPPLQLQVRREHVFHDSFRSLYYKKADELKFGKLNIRFQGEEGVDAGGVTREWFQVLSRQ 3775

Query: 3371 IFDKGALLFTTVGNE-STFQPNPNSVFQTEHLSYFKFVGRVVAKALFDGQLLDVHFTRSF 3429
+FD +LF V ++ +TF PN S EHL +FKF+GR++ KAL++G+LL+ +F+R+
Sbjct: 3776 MFDPNYVLFVPVSSDRTTFHPNKLSPINDEHLPFFKFIGRIIGKALYEGRLLECYFSRAV 3835

Query: 3430 YKHILGAKVTYHDIEAIDPDFFKNLKWMLENDTSDILDLTFSVDADEEKLILYERTEVTD 3489
YK ILG V+ D+E+ DPD++K+L WMLEND +DI+ TFSV+ D ++ +V D
Sbjct: 3836 YKRILGKPVSVKDMESFDPDYYKSLVWMLENDITDIITETFSVEDD-----VFGEVKVVD 3890

Query: 3490 YELIPGGRNVRVTEENKHEYVDLVAEHKLTTAIRPQINAFMEGFNELIPRELISIFHDKE 3549
LI GRN+ VTEENKHEYV L+ EHKL T+++ Q+ AF+ GF+E+IP ELI+IF+++E
Sbjct: 3891 --LIENGRNIPVTEENKHEYVRLIVEHKLITSVKDQMKAFLTGFHEIIPEELIAIFNEQE 3948

Query: 3550 LELLISGLPDIDLDDLRANTEYSGYSAASPVIQWFWEVVNGFSKEDKARLLQFVTGTSKV 3609
LELLISGLPDID+DD +ANTEY YSA +P IQWFW V F KE+ A+LLQFVTGTSKV
Sbjct: 3949 LELLISGLPDIDIDDWKANTEYHNYSAGAPQIQWFWRAVRSFDKEELAKLLQFVTGTSKV 4008

Query: 3610 PLEGFRALQGISGSQRFQIHKAYGSPDHLPSAHTCFNQLDLPEYPTKQQLQERLLLAIHE 3669
PL GF+ L+G++G RF IH+ YGS D LPS+HTCFNQLDLPEY + L+ +LL AI
Sbjct: 4009 PLNGFKELEGMNGVSRFNIHRDYGSKDRLPSSHTCFNQLDLPEYENYETLRSQLLKAITA 4068

Query: 3670 GNEGFGFG 3677
G++ FGF
Sbjct: 4069 GSDYFGFA 4076



Score = 77.8 bits (190), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 80/314 (25%), Positives = 133/314 (42%), Gaps = 45/314 (14%)

Query: 2592 IDPAFLDALPEELRAEVLS---AQQNQVAQPPAEQPQTNGDIDPEFLAALPPDIRAEVXX 2648
ID +L+ALPEE R EV++ + + A+ Q N ++ EFL ALP ++R E+
Sbjct: 2976 IDAEYLEALPEEFRDEVIAQAISTRRSQAREQVSQEGENTEVFQEFLEALPEELRNEILH 3035

Query: 2649 XXXXXXXXXXXE--LEGQ---PVEMDTVSIIATFPSDLREEVLLTSSDAILANLTPALVA 2703
+ GQ P +MD SI+ TFP LR++VLL + I+ +L P L A
Sbjct: 3036 QEQHEQRRRERQNAAGGQDLGPADMDPASILLTFPPGLRQQVLLDQGEDIMEHLGPELAA 3095

Query: 2704 EANML--RERFAHRYHGGTLFGMFPRNRRGESSGRGDTGPSSLDRGGIVSRRSNGSKLVE 2761
EA L R R H GG + S R P+ G + K+ +
Sbjct: 3096 EARTLVARHRQLHAQQGG----------QAASRSRDAQRPTEAGAGTV-------QKIQK 3138

Query: 2762 ADGAPLVDTDALKAMIRLLRVVQP-LYKGQLQRLLLNLCAHRETRTALV-------QXXX 2813
++D + ++RL+ V Q + L + NLC +R+ R ++ Q
Sbjct: 3139 RTVVQMLDKQGIATLLRLMFVSQQGSIRSSLFSIFANLCENRQNRLDVISSLLQILQDGC 3198

Query: 2814 XXXXXXERGMGSTSTYAGEPSYRLYACPNNVIYSR----------PQFLDGVPPLVSRRV 2863
ER S A + + P+ + S P + P L+ ++
Sbjct: 3199 ANMDAVERSFAQISHKAKQLKEKDAKTPHPLKRSLTGGTNNNGQFPASSEVSPLLIVQQC 3258

Query: 2864 LEVLIYLARNHPYV 2877
L++L+ L++ +P++
Sbjct: 3259 LDLLVELSKLNPHI 3272



Score = 53.1 bits (126), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 23/201 (11%)

Query: 1509 VPKWVTASLLAIDEMLQVDPKPSSEISDQSRKDETKTENSLVNDENASSNKLQTSLGLTA 1568
+P W+ LL + ML D +P Q K++ E S++ E N L A
Sbjct: 1769 LPPWIPYILLIFEIMLFKDAQPPDIKWKQPVKEDDPIEESVI--EVKEPNFL-------A 1819

Query: 1569 RHTTLPEQKRLIEIACGFIRDQLPSETMHV-VLQLCATLTRVHAVSVTFLEAGGLHSLLS 1627
H + L+ F+ E++ V VL++ LTR HAV+ E L L
Sbjct: 1820 EH-----RSSLLTTLLDFLPRIGKEESLAVSVLRILVVLTRDHAVAKIVGEKKNLQRLFV 1874

Query: 1628 LPTVSLFSGFDNVAAT--------IVRHILEDPHTLQQAMESEIRHSLVAALNRNSNGRV 1679
+ +G + T I+RHI+ED TL+Q E++IRH + + ++ +
Sbjct: 1875 MAKQLCGAGSTRLKQTHISEHIRQILRHIIEDEETLRQIFETDIRHLMTSRQRPSAAPGL 1934

Query: 1680 TPRNFLTGLASVITRDPAVFM 1700
P+ +L A + R P F+
Sbjct: 1935 EPQAYLRTQAHLALRSPKTFV 1955



Score = 50.8 bits (120), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 74/148 (50%), Gaps = 11/148 (7%)

Query: 485 VAVTLFRDLGGLEFLIQRL--QVELSRVIDASSLNDKSPSIGEALIFDDEMLFSQKRLIK 542
A + GGL+ + + V S+ + + L K P + +L+ D + F ++ +K
Sbjct: 597 TAFSQLNSAGGLDAITNLIVHTVGESKTLTEAGLGTK-PELHASLV-DYSIPFYHQQTLK 654

Query: 543 TLLKAL-----GSATYTASNSSRPQSSY--ETSLPASLSLIFRNAKRFGGDIYASGVTVM 595
LLK + + ++ +N+ R + +SL SL I R + FG ++++ T++
Sbjct: 655 WLLKFIHHVMANTYSFDGTNTERLLRNLVDNSSLLGSLCTIARQNRFFGTVVWSNATTLL 714

Query: 596 SEIIHKDPTCFPILYESGLPNAFLSSVT 623
S+ I+ DPT F + ESG AFL SVT
Sbjct: 715 SDFINNDPTSFAAISESGWIQAFLESVT 742

Query: CNT0023163
Subject: sp|Q756G2|TOM1_ASHGO Probable E3 ubiquitin-protein ligase TOM1

OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
GN=ptr1 PE=1 SV=1

 Score =  464 bits (1195), Expect = e-130,   Method: Compositional matrix adjust.
Identities = 211/426 (49%), Positives = 308/426 (72%), Gaps = 10/426 (2%)

Query: 3255 FVKFSEKHRKLLNSFIRQNPGLLEKSFSIMLKVPRFIDFDNKRAHFRSKIKHQH-DHHHS 3313
F+ F+E+HRK++N + P L+ SFS+++K P+ ++F+NKR +F ++ + +
Sbjct: 2809 FISFTEEHRKIINMMVFTTPSLMSGSFSLLVKNPKVLEFENKRNYFNRQLHEEAAKEQYP 2868

Query: 3314 PLRISVRRAYILEDSYNQLRMRSTQDLK-GRLTVHFQGEEGIDAGGLTREWYQLLSRVIF 3372
PL I+VRR ++ DSY L + ++K +L +HF+ EEG+DAGG+TREW Q+L+R +F
Sbjct: 2869 PLNITVRRDHVFLDSYRALHFKDADEVKFSKLNIHFRDEEGVDAGGVTREWLQVLARQMF 2928

Query: 3373 DKGALLFTTV-GNESTFQPNPNSVFQTEHLSYFKFVGRVVAKALFDGQLLDVHFTRSFYK 3431
+ LF V G+ +TF PN +S +HLS+FKF GR++ KAL+DG+LLD HF+R+ YK
Sbjct: 2929 NPDYALFLPVTGDATTFHPNRDSSVNPDHLSFFKFTGRIIGKALYDGRLLDCHFSRAVYK 2988

Query: 3432 HILGAKVTYHDIEAIDPDFFKNLKWMLENDTSDILDLTFSVDADEEKLILYERTEVTDYE 3491
H+L V+ DIE++DPD++K+L WML ND +DI+ F+V+ D + E+T V +
Sbjct: 2989 HMLHRSVSVKDIESLDPDYYKSLVWMLNNDITDIITEEFAVEKD----VFGEKTVV---D 3041

Query: 3492 LIPGGRNVRVTEENKHEYVDLVAEHKLTTAIRPQINAFMEGFNELIPRELISIFHDKELE 3551
LIP GRN+ VTE NK YV+ + ++KL +++ Q+ + ++GF+++IP LI IF+++ELE
Sbjct: 3042 LIPNGRNIPVTELNKQNYVNRMVDYKLRESVKDQLKSLLDGFSDIIPSHLIQIFNEQELE 3101

Query: 3552 LLISGLPDIDLDDLRANTEYSGYSAASPVIQWFWEVVNGFSKEDKARLLQFVTGTSKVPL 3611
LLISGLP+ID+DD + NTEY GY+ +SP +QWFW V F +E++A+LLQF TGTSKVPL
Sbjct: 3102 LLISGLPEIDIDDWKNNTEYHGYNVSSPQVQWFWRAVRSFDEEERAKLLQFATGTSKVPL 3161

Query: 3612 EGFRALQGISGSQRFQIHKAYGSPDHLPSAHTCFNQLDLPEYPTKQQLQERLLLAIHEGN 3671
GF+ L+G+SG QRF IHK+YGS + LP +HTCFNQLDLPEY T +QL+ LL AI+EG+
Sbjct: 3162 NGFKELEGMSGFQRFNIHKSYGSLNRLPQSHTCFNQLDLPEYDTYEQLRSMLLTAINEGS 3221

Query: 3672 EGFGFG 3677
EGFGF
Sbjct: 3222 EGFGFA 3227



Score = 129 bits (324), Expect = 6e-28, Method: Compositional matrix adjust.
Identities = 107/431 (24%), Positives = 198/431 (45%), Gaps = 16/431 (3%)

Query: 285 VPQEQRFSLLTRIRYARAFRSVRISRQYSRICLLAFIVLVQSSDAHEELVA--FFANEPE 342
+P++ F LL + + + R RI LLA LV AH + V F +PE
Sbjct: 253 IPEQYSFDLLVSLMLRQNLYDINRRRLMIRIGLLALSNLVY---AHSQAVQTRFLIADPE 309

Query: 343 CTVELINLVRSVHAVPENIRTXXXXXXXXXXXXYSSSHERARXXXXXXXXXXXXNRMLLL 402
T L NLV +P+N + +++ + L++
Sbjct: 310 ITTHLANLVSPDVDLPQNFKAVCFECFKAFF------FKKSMIPSVLASLNVSVSYGLMM 363

Query: 403 SVLQKAVMSLSSPTDPSSVLFVDAMLHFFLLHVXXXXXXXXXXXXXXLVPALLPLLQDNH 462
++++ +L +P +VD+ + FL + L L L
Sbjct: 364 NLVRDFSKNLENPNFYYEREYVDS-FYDFLQFMTSSPLGGNMACSAGLTSLLGYHLSVKT 422

Query: 463 PGHMHLVCTAVKIIQKLMDYSNVAVTLFRDLGGLEFLIQRLQVELSRVIDASSLNDKSPS 522
P ++V ++ ++ L+D ++A F + GL+ L+ R+Q EL + +P
Sbjct: 423 PQATYVVARSIVMLDHLIDGYSMAFPDFSESKGLDMLVDRVQYELEAGLQDIKSGKGNPE 482

Query: 523 IGEALIFDDEMLFSQKRLIKTLLKALGSATYTASNSSRPQSSYETSLPASLSLIFRNAKR 582
I L D + + + L+K LLK + + + ++ ++SL +SL+ + + +
Sbjct: 483 I--VLNMDYAISYDRYFLLKNLLKFVLHLIQSGGSVVELRNLIDSSLISSLAFLLEHHEV 540

Query: 583 FGGDIYASGVTVMSEIIHKDPTCFPILYESGLPNAFLSSVTEGILPSSRAVSCVPNGLGA 642
+G +++AS +MS IH +PTC+ I++E L +AFL +V IL SS A++ +P GA
Sbjct: 541 YGSNLFASTTNIMSTFIHNEPTCYGIIHEKKLSHAFLDAVNRKILNSSDAITSIPLAFGA 600

Query: 643 VCLNPKGLEAVKEQNALRFLITIFTSRKYLVAL--NEGIVPLANAVEELLRHVSSLRGTG 700
+CLN +G + E+N + L +IFTS + +L ++ L ++EL+RH SL+
Sbjct: 601 ICLNSQGFDLFLEKNPIPQLFSIFTSLNHCKSLISSDNAAILGTYIDELMRHQPSLKDPI 660

Query: 701 VDIIVEILEKL 711
V +I + +++
Sbjct: 661 VKMIFKACDQV 671

Query: CNT0023163
Subject: sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo

OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) GN=TOM1 PE=3 SV=2

 Score =  446 bits (1147), Expect = e-124,   Method: Compositional matrix adjust.
Identities = 224/484 (46%), Positives = 313/484 (64%), Gaps = 32/484 (6%)

Query: 3201 ILPYIESFFVTCEKLGPGQLGPGYDFANVSTPEAEDASQKSSASHSKVDDK--HGAFVKF 3258
+LP IES V C+ + E +DA K A F F
Sbjct: 2800 LLPLIESLMVVCK--------------HSKVRETKDALLKYEAKKCDFARTPVENLFFAF 2845

Query: 3259 SEKHRKLLNSFIRQNPGLLEKSFSIMLKVPRFIDFDNKRAHFRSKIKHQHDHHHSPLRIS 3318
++ H+KLLN IR NP L+ FS+++K P+ +DFDNKR +F ++++ H L IS
Sbjct: 2846 TDLHKKLLNEMIRSNPKLMSGPFSLLVKNPKILDFDNKRYYFTAQLR-AITHDRPKLSIS 2904

Query: 3319 VRRAYILEDSYNQLRMRSTQDLK-GRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGAL 3377
VRR ++ DSY L +S +D+K +L + F+GE G+DAGG+TREWYQ+LSR +F+
Sbjct: 2905 VRREHVFLDSYRSLFFKSNEDIKISKLEISFKGEAGVDAGGITREWYQVLSRQMFNPDYA 2964

Query: 3378 LFTTVG-NESTFQPNPNSVFQTEHLSYFKFVGRVVAKALFDGQLLDVHFTRSFYKHILGA 3436
LF V +++TF+PN S EHLS+FKF+G ++ KA+ D LD HF+R YK+ILG
Sbjct: 2965 LFIPVASDKTTFRPNRTSGINPEHLSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGK 3024

Query: 3437 KVTYHDIEAIDPDFFKNLKWMLENDTSDILDLTFSVDAD---EEKLILYERTEVTDYELI 3493
V D+E++D D++K+L W+LEND +DI++ TFSV+ D E K+I ELI
Sbjct: 3025 PVALKDMESLDLDYYKSLIWILENDITDIIEETFSVETDDYGEHKVI----------ELI 3074

Query: 3494 PGGRNVRVTEENKHEYVDLVAEHKLTTAIRPQINAFMEGFNELIPRELISIFHDKELELL 3553
G +V VTE+NKH+YV + E+KL T+++ Q+ F++GF +IP++LISIF ++ELELL
Sbjct: 3075 ENGAHVAVTEQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELL 3134

Query: 3554 ISGLPDIDLDDLRANTEYSGYSAASPVIQWFWEVVNGFSKEDKARLLQFVTGTSKVPLEG 3613
+SGLPDID+DD + NT Y Y+ I +FW V F KE++A+LLQFVTGTSKVPL G
Sbjct: 3135 VSGLPDIDVDDWKNNTIYVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNG 3194

Query: 3614 FRALQGISGSQRFQIHKAYGSPDHLPSAHTCFNQLDLPEYPTKQQLQERLLLAIHEGNEG 3673
F+ L G++G +F IH+ YGS D LPS+HTCFNQLDLP Y + + L+ LLLAI+EG+EG
Sbjct: 3195 FKELSGVNGISKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEG 3254

Query: 3674 FGFG 3677
FG
Sbjct: 3255 FGIA 3258



Score = 70.5 bits (171), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 59/254 (23%), Positives = 127/254 (50%), Gaps = 16/254 (6%)

Query: 450 LVPALLPLLQDNHPGHMHLVCTAVKIIQKLMDYSNVAVTLFRDLGGLEFLIQRLQVELSR 509
L+ +LL ++ + + + +A +++ ++ ++ A F + G LIQ + E++
Sbjct: 426 LISSLLEIVSTQNSKYKRTLASAAHLLEDVISDAD-ATAEFINNNGFNILIQTVTYEVNF 484

Query: 510 VIDASSLNDKSPSIGE----ALIFDDEMLFSQKRLIKTLLKALGSATYTASNSSRPQSSY 565
+ ++PS E ++++ + F Q I++LLK + T S R ++
Sbjct: 485 AV-------QNPSSAEPPKYSVVYY-SISFRQLGFIRSLLKLVLKLLKTDS-GDRIRNLI 535

Query: 566 ETSLPASLSLIFRNAKRFGGDIYASGVTVMSEIIHKDPTCFPILYESGLPNAFLSSVTEG 625
++ + + + I N FG + + + V+ II+ +PT + +L ESG L + +
Sbjct: 536 DSPILLAFNKILENRPVFGYTLVSHALDVVQTIINTEPTIYQVLVESGTIPYILQNFDQF 595

Query: 626 ILPSSRAVSCVPNGLGAVCLNPKGLEAVKEQNALRFLITIFTSRKY--LVALNEGIVPLA 683
+ P+S + +P + A+CLN GL+ VKE+N L++L + + ++ +++ + V
Sbjct: 596 LGPTSDLLCMLPEVISAICLNTDGLKQVKEKNLLKYLFQVIKTPEFAKILSWEDQAVNYG 655

Query: 684 NAVEELLRHVSSLR 697
A++EL RH L+
Sbjct: 656 VALDELARHYPELK 669



Score = 51.2 bits (121), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 53/183 (28%), Positives = 77/183 (42%), Gaps = 30/183 (16%)

Query: 2629 DIDPEFLAALPPDIRAEVXXXXXXXXXXXXXELEGQPVEMDTVSIIATFPSDLREEVLLT 2688
D+D EFL ALP DIRAEV EG E+D + T P LR+E
Sbjct: 2334 DMDAEFLNALPDDIRAEVFAQHIREYRTQFQGSEGSSRELDA-GFLNTIPETLRQE---- 2388

Query: 2689 SSDAILANLTPALVAEANMLRERFAHRYHGGTLFGMFPRNRRGES-SGRGDTGPSSLDRG 2747
ILA P ER A ++ G+ RNR GE S D P R
Sbjct: 2389 ----ILAQEVPL---------ERNAR----PSILGL--RNREGEEFSEVEDESP----RF 2425

Query: 2748 GIVSRRSNGSKLVEADGAPLVDTDALKAMIRLLRVVQPLYKGQL-QRLLLNLCAHRETRT 2806
S+ +K APL+D + A+++ + + QP ++ L LC+ ++ R+
Sbjct: 2426 NEQRTESSKTKTDRVHFAPLLDRSGIAAIMKAVFIPQPYLSREIYHELFYRLCSSKQNRS 2485

Query: 2807 ALV 2809
++
Sbjct: 2486 DIM 2488