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Query: CNT0024955
Subject: sp|O94248|MDN1_SCHPO Midasin OS=Schizosaccharomyces pombe (strain 972
SV=2

 Score = 1623 bits (4204), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 935/2308 (40%), Positives = 1352/2308 (58%), Gaps = 237/2308 (10%)

Query: 1    MAVNQKWPILLYGPVGAGKTALINKLAQIGGN-RVLFIHMDEQMDGRTLIGSYVCTEKPG 59
            +AV    PIL+ G  G+GKT +I +L++I GN  ++ IH+ +Q D + L+G+Y+ ++ PG
Sbjct: 290  IAVGLGKPILIEGVTGSGKTTMIEELSRITGNDNIIRIHLGDQTDSKVLLGTYITSDTPG 349

Query: 60   EFKWSPGSLTQAVIKGFWIVFEDIDKAPSDVQSILLPLLEGSSSFSVGHAEAVEVAENFR 119
            EFKW  G+LTQAV +G WI+ EDID AP +V S+L+PLLE  + F  G  E +E +  F+
Sbjct: 350  EFKWQAGALTQAVQEGRWILIEDIDLAPIEVLSVLIPLLENRTLFIPGRGEVIEASNGFQ 409

Query: 120  LFATVTTSKNDVSHALEGRLT-FSALWRKVMVGEPNRKDMIDIIHGCYPSLESISAKLID 178
            LFAT T      SH+ +      S LW +V++   +  +M  ++   +P L  + +K I+
Sbjct: 410  LFATQTLFG---SHSRDQNANILSHLWTRVVIEALSPTEMKQVLLTLFPQLTVMISKFIE 466

Query: 179  TFEKANLLVSYQ----------FGGLNLAGGSSECLV----------------------Q 206
            TF     ++S Q           G  N+A  ++   +                       
Sbjct: 467  TFNLLLRVISNQSISISPTDEVAGIANIANTANVNNINNNNNTDNNNNNNSNEKFIIPSS 526

Query: 207  RF-SLRDLLKWCKRI--RGVDLNFKGLGLSSSCCKLIYFEAVDIFASSLSSLDKRLYVAR 263
            RF S RDL+KW +R   R    N     ++S+  ++++ EA+D F S +S  + R  + +
Sbjct: 527  RFISSRDLIKWIRRCNQRLHLTNVSQQIITSTMQEIVFVEALDCFCSMISKKNLRKQLTQ 586

Query: 264  EIAKLF-----CVPHGAETISPSDKPIIQARHTDLQVGRVTLQCSDKPALIQ-------- 310
             I +++      + +  E   PS    I      +  GR  L+  +K   IQ        
Sbjct: 587  VIGRVWELTGDRINYYVELYKPS----IIITQESVSTGRAKLKSLEKSDSIQISNGKKHT 642

Query: 311  ----------------KGPFADIRRALEVLERVACSIKFNEPVLLVGETGTGKTTLVQNL 354
                               FA    +L ++E+++ SI+FNEP+LLVGETGTGKT++VQ +
Sbjct: 643  RFTTEQSQQDSGVTKHGNVFAHTMNSLRLMEKISISIQFNEPILLVGETGTGKTSVVQYI 702

Query: 355  ASWLKQPLTVVNLSQQSDISDLLGGFKPADARSICFPLYIEFKDLFCRSFSGKDNEAILR 414
            A  L Q L V+NL+QQSD SDL+GGFKP + R +C PL   F  +F ++FS  +N   L 
Sbjct: 703  ADQLNQKLVVLNLNQQSDSSDLIGGFKPVEMRLLCLPLKNRFDSMFKKTFSESNNTDFLE 762

Query: 415  HCDVYVMEKKWKKLLRALEKCVEKAQKLI--------------------DXXXXXXXXXX 454
              D   + K WK+ +  L K ++  +  +                    +          
Sbjct: 763  KIDKAFISKNWKQFIALLNKAIKLVENKVLKDDQTTTNNTKENNNNNNNNNNNNNNNNNN 822

Query: 455  XXXPLPAQVISDWDSFSSRLNAACSQI-GSEIGMSFQFVEGAFVSALRNGHWILLDEVNL 513
                + ++V   W   S+ +     Q   S+   +F FVEG+ V+ +R G+W+LLDE+NL
Sbjct: 823  KKRTIRSEVKEKWIKLSNDIKKLTIQFEKSKNNFAFSFVEGSLVNCIRKGYWVLLDEMNL 882

Query: 514  APPETLQRIGAVLDGESGTLCLAERGDVDYIERHPCFRMFACMNPATDAGKRELPYTFRS 573
            A  ETL+ +  + DG  G++ L E+G+V+ +ERHP F++FACMNP TD GK++LP   R+
Sbjct: 883  ATSETLESLSGLFDG--GSITLTEKGEVEPVERHPNFKVFACMNPPTDIGKKDLPPGIRN 940

Query: 574  RFTEFFVXXXXXXXXXXXFVSKYLDGLHAAKGVADSIVRFYKAAKKESEEKLQDGANQKP 633
            RFTE++V            V   L  L     + D IV FY   K++++ K+ DG+NQKP
Sbjct: 941  RFTEYYVDDLDNRGDLCLVVKTVLSNLVPNPPIED-IVEFYLKTKQDAQNKMLDGSNQKP 999

Query: 634  QFSLRSLSRSLGYIKNAERKFGFKKALYDGFCMFFLTMLDAPSAKIINNLIVSLLLDGRV 693
             FSLR+LSR+L Y K+  + FGF++AL++G  M FLT L+  S  ++  LI   +  G V
Sbjct: 1000 IFSLRTLSRALNYTKHVTKSFGFQRALFEGISMSFLTQLNKSSYPMMEQLIKQYIKKGEV 1059

Query: 694  P------------------------PRISFADYFVEKPKLLNGSESDDFLRSYVLTNSVT 729
                                       +    +++E      G+E       Y+LT S+ 
Sbjct: 1060 KLYNQPLNRPPPTSTTNNNNNNAEESYVKIEQFWIE-----CGNEKPIIPTHYILTPSIK 1114

Query: 730  EHIVNLACAVYIKKYPVLLQGPTSSGKTSLVRFLAAQTGHEFVRINNHEHTDLQEYLGTY 789
             ++ N+A  +  +K+P+LLQGPTSSGKTS+V +LA +TGH F+RINNHEHTDLQEYLG Y
Sbjct: 1115 SNLSNIARVLVSRKHPILLQGPTSSGKTSMVEYLAIRTGHRFIRINNHEHTDLQEYLGQY 1174

Query: 790  VTDSHGKLQFQEGALVKAVREGHWIVLDELNLAPSDVLEALNRLLDDNRELFVPELQETI 849
            ++D  GKL FQEG LV+AVR+G+W+VLDELNLAPS+VLEALNRLLDDNRELF+PE QE +
Sbjct: 1175 ISDDKGKLVFQEGILVEAVRKGYWVVLDELNLAPSEVLEALNRLLDDNRELFIPETQEVV 1234

Query: 850  PAHPNFMLFATQNPPVLYGGRKILSRAFRNRFIEVHVDEIPEDELITILEQRCSIACSYA 909
              HP+FMLFATQNPP LYGGRK+LSRAFRNRF+E+HVD+IPEDEL  IL +RC++  SY 
Sbjct: 1235 RPHPHFMLFATQNPPGLYGGRKVLSRAFRNRFLELHVDDIPEDELEEILCKRCALPPSYC 1294

Query: 910  TRMVQVMKDLQTHRQNS-RVFAGKHGFITPRDLFRWANRYRLFEGKSYEDLAKDGYLLLA 968
             ++V +MK+LQ +RQ S +VFAGKHG IT RDLFRWA R    +  SYE+L   GY LLA
Sbjct: 1295 KKLVLIMKELQLNRQGSNQVFAGKHGAITFRDLFRWAER----QPSSYEELGIAGYQLLA 1350

Query: 969  ERLRDDTEKAVVQEVLERHLHVKLSISNLYNMEVSCDNN---------LSRESIRLRVQE 1019
            ERLR D EK ++++V+E+HL +KL I ++Y    SCD+          LS     L    
Sbjct: 1351 ERLRKDEEKLIIKQVIEKHLKIKLDIESIY----SCDDKPEFLKLLQLLSENDSELSKSN 1406

Query: 1020 TFGNITWTESMWRLYFLIERCYRSREPVLLVGETGGGKTTVCQVLSAVLGVKLHILNCHQ 1079
                I WT SM RL+ L+ +C   +EP+LLVGETG  KTT+CQ+ S +   KLHILNCHQ
Sbjct: 1407 HLEKIVWTRSMKRLFSLVGKCLEHKEPILLVGETGCSKTTICQLYSILNKQKLHILNCHQ 1466

Query: 1080 YTETSDFIGGFCPIRDR----SKIAMEFKHLITKMKQLKIFIHVAGDMSFPADISGAVSV 1135
            +TET+DFIGG  P+R R    SK+    K    ++ QL ++     +             
Sbjct: 1467 HTETADFIGGLRPVRGRDQVLSKLYSLVKQYFNQLSQLNLYKLEQEN------------- 1513

Query: 1136 VNHIDEILDRYIKEK---ELFPQVPPHDFAA--MEQIKLDLMQLHKRWQAIFLWQDGSLV 1190
             N+IDE+  + I E+   E + QV         ++Q+ +++ + +  + ++F W DG LV
Sbjct: 1514 -NNIDELPIKEIMERLIVESWKQVSNSSLLTEQLKQLAIEIDKTYSSYCSLFNWVDGPLV 1572

Query: 1191 QAMKNGDLFLIDEISLADDSVLERLNSVLEPERKLSLAEKGGSVLEKVVAHPNFFILATM 1250
            +AMK GD FLIDEISLA+D+VLERLNSVLEP R L LAEKGG  +E++  H  F ILATM
Sbjct: 1573 EAMKQGDYFLIDEISLAEDAVLERLNSVLEPSRLLVLAEKGGVEIEELRGHKEFRILATM 1632

Query: 1251 NPGGDYGKKELSPALRNRFTEVWVPAVTNVDELKSIAIERFTNAEVSCFGDCIVNFWMWF 1310
            NPGGD+GKKELSPA+RNRFTE+WVPA+++  +L  I  ERFT+ ++   G  ++NF  + 
Sbjct: 1633 NPGGDFGKKELSPAMRNRFTEIWVPAISSHQDLLQIIEERFTSPQLKGKGSLMLNFIEYL 1692

Query: 1311 NQLHTG-RMLTIRDLLSWISFINVT--ERNLGPQQAXXXXX-XXXXXXXXXXXMNVSKTE 1366
              +    R++++RD+LSWISF+N+   ++ L P ++                  + S++E
Sbjct: 1693 LMIQKNKRVISLRDILSWISFMNLCMDKQLLSPNESYIHGACLVLLDGFGMGSNSSSESE 1752

Query: 1367 ATELRRTCLSFLLEELQKVEGK-PLNSDLHDLKNYGWGDHTREIDI-GQPDHFGIMPFYI 1424
              +LR  CL  L+++++  + K  L ++L    +      +   +I  + + FGI PFYI
Sbjct: 1753 GLKLREACLIRLIDQIESQDEKLKLQTELLSTSSSSSSLSSSIANIIKEENRFGIHPFYI 1812

Query: 1425 DTGHFTRKQQGFQFMAPTTSKNVFRVLRGMQLPKPLLLEGSPGVGKTSLIVALAGFSGHN 1484
                    +  F   APTTSKN  RVLRGMQLP+ +L+EGSPGVGKTSLI A+A  SG+ 
Sbjct: 1813 PVRESNVPKIQFSLSAPTTSKNAQRVLRGMQLPRAILVEGSPGVGKTSLITAIANASGNQ 1872

Query: 1485 VVRINLSEQTDMMDLLGSDLPVEGENGMEFAWSDGILLQALKNGSWVLLDELNLAPQSVL 1544
            +VRINLSEQTD+MDLLGSDLPVEG  G +F W DG+ L+AL+NGSWVLLDELNLA Q+VL
Sbjct: 1873 IVRINLSEQTDIMDLLGSDLPVEGGTGGQFEWRDGVFLEALRNGSWVLLDELNLASQTVL 1932

Query: 1545 EGLNAILDHRAEVFIPELGQTYKCPPSFRVFACQNPSSQGGGRKGLPKSFLNRFTKVYVD 1604
            EGLN+ LDHR+EV+IPELG+T+ C P+FRVFACQNP  QGGGRKGLPKSFLNRFT+V++D
Sbjct: 1933 EGLNSCLDHRSEVYIPELGKTFACHPNFRVFACQNPLHQGGGRKGLPKSFLNRFTQVFID 1992

Query: 1605 ELSESDYSFICKSQYPSIKDDILKKLISFNNRLYMDTMIHKKYGQEGSPWEFNLRDIIRS 1664
            +L++ D  FI  + YP+I    ++++I FN++++ ++MI  K+ ++G+PWEFNLRD  R 
Sbjct: 1993 QLNQQDLLFISTAMYPTIPSKTIERMIEFNHQMFKESMIEHKFARKGAPWEFNLRDTFRW 2052

Query: 1665 CEMIVGACETARGYPETSMVDCFLNTVYLQRMRTVADREEVVKLFEEVFQTKYSIHE--I 1722
            C++IV    T+   P       F++ +YLQRMRT+ DRE V+ +F+ VF T    ++  I
Sbjct: 2053 CDLIVKD-PTSISNPAR-----FIDLIYLQRMRTLQDREHVLTIFKRVFTTSGDENDQSI 2106

Query: 1723 KML------------YVNPQCLVVGSASIRR------NRVHSCKVQN-SQLNILPGTLHS 1763
             M+             ++P+ L +GS+ + R      +   S  + N S + +L   L+ 
Sbjct: 2107 DMMPTICNYDKQPHYSISPEYLQIGSSILPRVQNGGASSFDSSVLDNSSNIQLLQRLLNP 2166

Query: 1764 LEAAMHCINQGWLCILVGQHSSGKTSLIRLLAQLSGNTLNEVNLSSATDVSELLGCFEQY 1823
            LE  M CI   W+ IL+G  S+ KTS IRLLAQL+GNTL E +++S+ D +E+LG FEQ 
Sbjct: 2167 LENIMKCIEMNWMSILIGPTSTSKTSSIRLLAQLTGNTLYEFSMNSSVDTTEILGGFEQI 2226

Query: 1824 NFFRHYKVVISQ-------VERYIDEYFSLSQYIQWKSLVADRKTLFVKWFEFVIAKKFS 1876
            +  R+ K +IS        V  +I  YF+ +     K+ ++  + +   W  F   K+  
Sbjct: 2227 DLVRYQKRIISSVSSLITIVSSHIMTYFNSNDDNLMKTCISSIQDIHQVWNLF--KKQTQ 2284

Query: 1877 SICISTLVEMSKNSS-------LPSLSLVRDIVEDMKCDMEMFDLPVSFNKDDLSKTLRS 1929
                    + +   S       +  L L+  IV+ ++       L + FN D+  + L  
Sbjct: 2285 QTQQQIQQDGATIGSGGVGLITIEQLDLLSTIVDALE------KLSIQFNLDNNQEHLNR 2338

Query: 1930 IYYLQQSEAVHQPVK-------FEWVAGDLIRAIECGEWIVLDNANFCNPTVLDRINSLV 1982
            I  ++Q     + ++       FEW+ G LI+A+E G WI++DN NFCNPTVLDR+N L+
Sbjct: 2339 IQDVRQQIQRIKSIEKESVTGCFEWIDGLLIKALETGAWILIDNVNFCNPTVLDRLNPLL 2398

Query: 1983 EQERSIVVNECGLVDGNPVILKAHPKFRMFLTINAKHGEVSRAMRNRGVEIFLMNQNLSI 2042
            EQ+  +++NE G+VDG   ++K HP FR+FLT++ K GE+SRAMRNRG+EI++    LS+
Sbjct: 2399 EQDGVLMLNERGMVDGQVKVVKPHPNFRIFLTMDDKKGEISRAMRNRGIEIYMAADQLSL 2458

Query: 2043 NGCSNAAEDSERRDITRFLISCGIPRMELVSSMSEAH--LYAKAAGLRLGINITLLEITR 2100
                     S   D  + L + GIP   L  +M + H  ++ + +   +    TL ++  
Sbjct: 2459 -----METPSNNFDNQQLLTALGIPLESLTRTMIDFHNQIFTQLSS-TIENPCTLSQLLY 2512

Query: 2101 WVQLFKQLLIKGNQFLWSLHLSWEHTYL 2128
            W +L    L +G   L S+  S E  Y+
Sbjct: 2513 WGKLILDQLQRGFSLLNSIRNSMEQIYI 2540



 Score =  285 bits (730), Expect = 5e-75,   Method: Compositional matrix adjust.
 Identities = 199/649 (30%), Positives = 318/649 (48%), Gaps = 100/649 (15%)

Query: 4471 EQEHAEDGQMETNNMEKELHNIESLEHP-----SQGIQPNNAEMDYNRESESNLANSTDM 4525
            E+E  E+ Q      E++    +  E P       G + N +  D   + ESN  N+ D 
Sbjct: 5278 EKEQPEEDQTSLTTNEQQDETPKDSEQPLGVKDKTGSKSNVSNTDEEMKDESNQDNADDD 5337

Query: 4526 NSAAAPSVNFSSNEVPSLEISMPNSGDGSRLLSNSKPELQTDTPPSQIKQT--NPFRSIG 4583
            +    P+   S N+  +L+           L S   P+     PP + KQ   NP+RS+G
Sbjct: 5338 SGMTQPTP--SENDTGALK----------NLKSQPPPQSSAQQPPKKQKQVDPNPYRSMG 5385

Query: 4584 DAMADWKERAKVSADT-----------QDHQPEAEHHIDDESATEFRYVPDSE-----QS 4627
            DA  +WK+R  +  +            ++  P+ + +  +    ++ ++ D E     + 
Sbjct: 5386 DANKEWKKRLNLKQEQEEEEEEQSSEPKEKAPKQDPNAKENENQDYEFIKDDEKLDKDEE 5445

Query: 4628 TSQALGNATADQINDDLQVKQSSMEDENRVQKE-------------------EHNTDRAP 4668
            T QAL  AT  Q+ D   + Q+  +D+   Q+E                   EH  D   
Sbjct: 5446 TDQALAAATDTQLQD---IPQNKAQDDQAEQEEDQMDIDEEDDMDVDHKQEVEHQDDSKQ 5502

Query: 4669 GDDHNLEVPHLQASQ-----------------SRTNKSENANNLEHREIQTDTYVQDSVQ 4711
              D N ++   +  Q                  +  + +  + L  +E  T   +++   
Sbjct: 5503 QLDENKKISMSKLKQDQLKQQKEKEKEKLEKDQQDGQDDELDGLNQKEQFTKEQLENLTN 5562

Query: 4712 ----------GETDETFGDFVSFKQPPADEKTVMRDDLANDRELSTPMEI-NITDVDMKG 4760
                      G+  E   D     +   +EK + R+DL   R+     +I N ++ ++  
Sbjct: 5563 LDKEKAVLDDGDDQEMEQDGDQDDEESVEEKKLTREDLDRMRQELEQYKIENSSNPEIGT 5622

Query: 4761 PIVDWKSVELTTMKLSQELAEQLRLVMEPTLASKLQGDYRTGKRINMKKVIPYIASHFRR 4820
             +  WK  E  T  LSQ+L EQLRL++EPTLA+KLQGDY++GKRINMKKVIPYIAS F++
Sbjct: 5623 EL--WKKYEQLTNDLSQDLCEQLRLILEPTLATKLQGDYKSGKRINMKKVIPYIASQFKK 5680

Query: 4821 DKIWLRRTKPNKRNYQVVIAVDDSRSMSEGKCGKVAIEALVTVCRAMSQLEVGQFAVASF 4880
            DKIWLRRTKPNKR YQV++A+DD+ SM+    G  A+EA+  + RAMS+LEVGQ  +  F
Sbjct: 5681 DKIWLRRTKPNKRQYQVLLAIDDTESMAAYHSGGFALEAMTMISRAMSRLEVGQLGIVRF 5740

Query: 4881 GKKGNVKVLHDFDQVFNGEAGTNMISSLSFEQDNKLEDEPVADLLMHLNTMLDTAVARSR 4940
            G+  +V+++H FDQVF+ + G  +I+   F+Q          +++  L+  L       +
Sbjct: 5741 GE--DVQLVHSFDQVFSDQTGPEIITQFKFQQTK-------TNMVNFLSKTLQIMDMNKQ 5791

Query: 4941 TPSGQNPLQQLVLIISDG-KFHEKENLKRCVRNVLNRKRMIAYVLLDG--HEESIMDSLE 4997
            + SG+ P  QLV I+SDG    + E  K+ +R    +   I ++++D   +  SI+D   
Sbjct: 5792 SSSGE-PAMQLVFIVSDGWSLRDPETTKKYLREASIKNVFIVFIVIDNPVNNNSILDFES 5850

Query: 4998 VSYQGTKLTMGKYMDSFPFPYYVMLKNIEALPRTLADLLRQWFELMQSA 5046
            +S+   K+    YM  FPF YYV+L+++  +P  L+D LRQWF+L +S 
Sbjct: 5851 ISFNNGKIQRTNYMSEFPFMYYVILRSLNNIPSILSDTLRQWFDLTKST 5899



 Score =  115 bits (287), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 80/224 (35%), Positives = 132/224 (58%), Gaps = 11/224 (4%)

Query: 719 LRSYVLTNSVTEHIVNLACAVYIKKYPVLLQGPTSSGKTSLVRFLAAQTGHE-FVRINNH 777
           ++  V TN+V++++ +LA AV + K P+L++G T SGKT+++  L+  TG++  +RI+  
Sbjct: 272 VQKLVYTNTVSQNLNSLAIAVGLGK-PILIEGVTGSGKTTMIEELSRITGNDNIIRIHLG 330

Query: 778 EHTDLQEYLGTYVT-DSHGKLQFQEGALVKAVREGHWIVLDELNLAPSDVLEALNRLLDD 836
           + TD +  LGTY+T D+ G+ ++Q GAL +AV+EG WI++++++LAP +VL  L  LL +
Sbjct: 331 DQTDSKVLLGTYITSDTPGEFKWQAGALTQAVQEGRWILIEDIDLAPIEVLSVLIPLL-E 389

Query: 837 NRELFVPELQETIPAHPNFMLFATQNPPVLYGGRKILSRAFRNRFIEVHVDEIPEDELIT 896
           NR LF+P   E I A   F LFATQ    L+G     SR  +N  I  H+      E ++
Sbjct: 390 NRTLFIPGRGEVIEASNGFQLFATQ---TLFGSH---SRD-QNANILSHLWTRVVIEALS 442

Query: 897 ILEQRCSIACSYATRMVQVMKDLQTHRQNSRVFAGKHGFITPRD 940
             E +  +   +    V + K ++T     RV + +   I+P D
Sbjct: 443 PTEMKQVLLTLFPQLTVMISKFIETFNLLLRVISNQSISISPTD 486



 Score =  100 bits (248), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 63/195 (32%), Positives = 113/195 (57%), Gaps = 7/195 (3%)

Query: 1442 TTSKNVFRVLRGMQLPKPLLLEGSPGVGKTSLIVALAGFSGH-NVVRINLSEQTDMMDLL 1500
            T S+N+  +   + L KP+L+EG  G GKT++I  L+  +G+ N++RI+L +QTD   LL
Sbjct: 280  TVSQNLNSLAIAVGLGKPILIEGVTGSGKTTMIEELSRITGNDNIIRIHLGDQTDSKVLL 339

Query: 1501 GSDLPVEGENGMEFAWSDGILLQALKNGSWVLLDELNLAPQSVLEGLNAILDHRAEVFIP 1560
            G+   +  +   EF W  G L QA++ G W+L+++++LAP  VL  L  +L++R  +FIP
Sbjct: 340  GT--YITSDTPGEFKWQAGALTQAVQEGRWILIEDIDLAPIEVLSVLIPLLENRT-LFIP 396

Query: 1561 ELGQTYKCPPSFRVFACQNPSSQGGGRKGLPKSFLNR-FTKVYVDELSESDYSFICKSQY 1619
              G+  +    F++FA Q  +  G   +    + L+  +T+V ++ LS ++   +  + +
Sbjct: 397  GRGEVIEASNGFQLFATQ--TLFGSHSRDQNANILSHLWTRVVIEALSPTEMKQVLLTLF 454

Query: 1620 PSIKDDILKKLISFN 1634
            P +   I K + +FN
Sbjct: 455  PQLTVMISKFIETFN 469



 Score = 89.7 bits (221), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 66/286 (23%), Positives = 131/286 (45%), Gaps = 10/286 (3%)

Query: 3362 TYNAYKDPNPSILFKMVEPLTALQEKVRYFLDEWPGHPGLLKILDIITSLLAIPLSTPXX 3421
            TYN Y+D N S +  + EPL + +++V   L E+P    L  ++ +I  L+  P + P  
Sbjct: 4026 TYNIYRDSNISEIGIIREPLISFRKRVFELLVEYPEQANLTLMVKLIDRLMTYPATDPLA 4085

Query: 3422 XXXXXXXXXXXXAQTLQENDSKFF-LKDHLPQLFIIVSSWQRLELECWPILLQEVLEKYE 3480
                        +   +   SK   +++HL ++  ++  W++LE+E WP + Q   ++ E
Sbjct: 4086 KILTGLELLLRKSLEWESFASKAVSIQNHLNEISSLIVRWRKLEIESWPSIFQSQEKEAE 4145

Query: 3481 SNALKLWFPLRALLT---QSCDXXXXXXXXXXXXXXXFVQTSSIGEFKRRLHLLLAFHGE 3537
              ALK WF L  L+     S +               ++ +SS+G+F  R+ LL +F+ +
Sbjct: 4146 VKALKSWFILYDLINDEPSSPELEDENLSKNFHTLQQYLYSSSLGDFLTRIELLKSFYKQ 4205

Query: 3538 LSDGAGVGAYSSNS--LKKIQNILYNMFGYYMQFLPLVLXXXXXXXXXXXXDLKDQVKLY 3595
            L+    +   S N+   +K+ +I+YN+F Y+  F+                   + ++L 
Sbjct: 4206 LNSTIKLIGTSKNTNYKQKLSDIIYNIFKYFENFISRFEDRLAKSIKPIEDKALEFIRLS 4265

Query: 3596 RWEQDPHSASIENFKR----TRQKVFKLLQCFNDILQKPVMVLLNQ 3637
            RW+ +      E  K+    + + + K+   + ++L +P+  +  Q
Sbjct: 4266 RWDDNRLLTQYERLKQHIEVSHRNLAKVTIKYKNVLAQPLHDIFTQ 4311



 Score = 52.0 bits (123), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 21/148 (14%)

Query: 3745 KKNQKKTALSNLFKTLEECGLSKHRPMGREGNELAAPSPFLEQSYITTHLLQQVISKK-- 3802
            K+ +K+ AL  L     E GLS H  + R       P   L+ SY+        IS    
Sbjct: 4456 KRQEKEFALKELMSKFHEMGLSYH--INR------YPQEQLQISYLFNVRHLPTISDNQG 4507

Query: 3803 -MPEDASVAHATLLSTNNWK---NANQQYFKCLAMMQQLRQISLKFNKDLGLEEVNRATS 3858
             +P     + + + + N  K    A+Q Y++ ++ + +LRQ+S+++N DL  + V R   
Sbjct: 4508 YLP----TSFSKITADNGAKLLDQADQYYYRIVSRVHRLRQLSIEYNSDLSSKHVQRING 4563

Query: 3859 FMDHLLSIMSEQRHFAYNMFEQLNEFRH 3886
            +++H LSI+  QR+   N+ + +N + H
Sbjct: 4564 YVEHFLSIIINQRN---NLIDSINSWNH 4588

Query: CNT0024955
Subject: sp|Q12019|MDN1_YEAST Midasin OS=Saccharomyces cerevisiae (strain ATCC
/ ATCC 24843) GN=mdn1 PE=1 SV=1

 Score = 1398 bits (3618), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 829/2075 (39%), Positives = 1183/2075 (57%), Gaps = 153/2075 (7%)

Query: 5    QKWPILLYGPVGAGKTALINKLAQIGGNRVLFIHMDEQMDGRTLIGSYVCTEKPGEFKWS 64
            QK PILL GP G GK  LI ++A   G +++ IH+ +  D + LIG+Y  + KPGEF+W 
Sbjct: 151  QKRPILLAGPEGIGKKFLITQIAAKLGQQIIRIHLSDSTDPKMLIGTYT-SPKPGEFEWQ 209

Query: 65   PGSLTQAVIKGFWIVFEDIDKAPSDVQSILLPLLEGSSSFSVGHAEAVEVAENFRLFATV 124
            PG LTQAVI G WI+F +I+ APS+V S+LLPLLE          E +    +F++FAT 
Sbjct: 210  PGVLTQAVITGKWILFTNIEHAPSEVLSVLLPLLEKRQLVIPSRGETIYAKGSFQMFAT- 268

Query: 125  TTSKNDVSHALEGRLTFSALWRKV-MVGEPNRKDMIDIIHGCYPSLESISAKLIDTFEKA 183
                     +++ ++    LW+ + +  +P+  + ++++   YP L  I   L   ++  
Sbjct: 269  --------SSMKTKILGQRLWQILDLTYQPD--ECVEVVSTLYPVLSIICPTLYSVYKDI 318

Query: 184  NLLVSYQFGGLNLAGGSSECLVQRFSLRDLLKWCKRIRGVDLNF----KGLGLSSSCCKL 239
              L S +      +  ++  + +R  LRD  K+ KR+  +   F      + +S      
Sbjct: 319  FDLFSQR------SFLATSKIYRRLCLRDFYKFIKRVAFLYHKFMIPSDHVVISQELQDA 372

Query: 240  IYFEAVDIFASSLSSLDKRLYVAREIAKLFCVPHGAETISPSDKPIIQARHTDLQVGRVT 299
            ++ EA+D+F + + S D    V R +A    +P           P+ Q    ++ +GR +
Sbjct: 373  VFKEAIDMFGAFIPSRDGFDLVVRNVAIELNIPPEKALQLRYSIPVFQNLEHNINIGRCS 432

Query: 300  LQCSDKPALIQKGPFADIRRALEVLERVACSIKFNEPVLLVGETGTGKTTLVQNLASWLK 359
            L+            +A    +L +LE++A  ++ NEP+LLVGETGTGKTT +Q LA  L 
Sbjct: 433  LKKLSTIRSCSTNSYAFTSSSLGLLEQLAAGVQTNEPLLLVGETGTGKTTTIQLLAGLLG 492

Query: 360  QPLTVVNLSQQSDISDLLGGFKPADARSICFPLYIEFKDLFCRSFSGKDNEAILRHCDVY 419
            Q +TV+N+SQQ++ SD+LGG+KP +A ++  PL+  F D+F ++FS K N   +      
Sbjct: 493  QKVTVINMSQQTESSDMLGGYKPINASTLGLPLHERFIDIFEQTFSSKKNAKFISMASTS 552

Query: 420  VMEKKWKKLLRALEKCVEKAQKLIDXXXXXXXXXXXXXPLPAQV--ISDWDSFSSRLNAA 477
                +WK  L+  ++  + ++ ++D              L  QV   + W  F   +   
Sbjct: 553  ARRFRWKTCLKIWKEACKLSKTVLDGQQPLPNPQKRQKRLSNQVELRNQWAKFEKEVEDF 612

Query: 478  CSQI-GSEIGMSFQFVEGAFVSALRNGHWILLDEVNLAPPETLQRIGAVLDGESGTLCLA 536
               + G   G  F FVEGA V A+R+GHW+LLDE+NLA  ETL+ IG +L      + L+
Sbjct: 613  EKVLTGGSNGFMFSFVEGALVKAVRSGHWVLLDEINLASLETLEPIGQLLSSYESGILLS 672

Query: 537  ERGDVDYIERHPCFRMFACMNPATDAGKRELPYTFRSRFTEFFVXX-XXXXXXXXXFVSK 595
            ERGD+  I  H  FR+F CMNP+TD GKREL  +FRSRFTE +V             + K
Sbjct: 673  ERGDITPITPHKNFRLFGCMNPSTDVGKRELEPSFRSRFTEIYVHSPDQNLDDLLSIIQK 732

Query: 596  YLDGLHAA-KGVADSIVRFYKAAKKES-EEKLQDGANQKPQFSLRSLSRSLGYIKNAERK 653
            Y+  L    + V   +   Y+ AK  S +  L DGA Q+P +++R+LSR+L Y+      
Sbjct: 733  YIGSLCIGNEHVIREVAELYQVAKSLSLDGSLVDGAGQRPHYTVRTLSRTLSYVTEIAPI 792

Query: 654  FGFKKALYDGFCMFFLTMLDAPSAKIINNLIVSLLLD--------------GRVPPR--- 696
            +G +++LY+GFCM FLT+LD  S  ++ N +V   L                +VP     
Sbjct: 793  YGLRRSLYEGFCMSFLTLLDHTSESLLYNHVVRFTLGELNRDQQNAILKQIPKVPDHSSY 852

Query: 697  ISFADYFVEKPKLLNGSESDDFLRSYVLTNSVTEHIVNLACAVYIKKYPVLLQGPTSSGK 756
            I+F  Y++ +     GS   +    Y++T  V ++++N+A A   + +P+L+QGPTSSGK
Sbjct: 853  IAFCHYWLRR-----GSFPVEEQEHYIITPFVQKNLLNIARACSTRMFPILIQGPTSSGK 907

Query: 757  TSLVRFLAAQTGHEFVRINNHEHTDLQEYLGTYVTDSHGKLQFQEGALVKAVREGHWIVL 816
            TS++ ++A +TGH+FVRINNHEHTDLQEY+GTYVTD +G L F+EG LV+A+R G+WIVL
Sbjct: 908  TSMIEYVAKKTGHKFVRINNHEHTDLQEYIGTYVTDDNGSLSFREGVLVEALRNGYWIVL 967

Query: 817  DELNLAPSDVLEALNRLLDDNRELFVPELQETIPAHPNFMLFATQNPPVLYGGRKILSRA 876
            DELNLAP+DVLEALNRLLDDNRELF+PE Q  +  HP FMLFATQNPP +Y GRK LSRA
Sbjct: 968  DELNLAPTDVLEALNRLLDDNRELFIPETQVLVKPHPEFMLFATQNPPGVYAGRKHLSRA 1027

Query: 877  FRNRFIEVHVDEIPEDELITILEQRCSIACSYATRMVQVMKDLQTHRQNSRVFAGKHGFI 936
            FRNRF+E+H D+IPE+EL TIL +RC IA SYA ++VQV ++L   RQ +R+F  K+ F 
Sbjct: 1028 FRNRFLEIHFDDIPENELETILHKRCKIAPSYAAKIVQVFRELSLRRQTTRIFEQKNSFA 1087

Query: 937  TPRDLFRWANRYRLFEGKSYEDLAKDGYLLLAERLRDDTEKAVVQEVLERHLHVKLSISN 996
            T RDLFRWA R    E   Y+ LA++GY+LLAER RD  +K  VQEV+E+ + VK+    
Sbjct: 1088 TLRDLFRWAFR----EAVGYQQLAENGYMLLAERARDQKDKLAVQEVIEKVMKVKIDTDG 1143

Query: 997  LYN---MEVSCDNNLSRESIRLRVQETFGNITWTESMWRLYFLIERCYRSREPVLLVGET 1053
            +YN   ME+  D +L         +     + WT  M RL+ L+ RC  ++EPVLLVG+T
Sbjct: 1144 IYNLDSMEIFQDMSLK--------EGPLSKVVWTRPMIRLFCLVWRCLLAKEPVLLVGDT 1195

Query: 1054 GGGKTTVCQVLSAVLGVKLHILNCHQYTETSDFIGGFCPIRDRSKIAMEFKHLITKMKQL 1113
            G GKTTVCQ+L+  L  +LHI+N HQ TE  D IG   P+R+RS +              
Sbjct: 1196 GCGKTTVCQILAECLHKELHIINAHQDTENGDIIGAQRPVRNRSAV-------------- 1241

Query: 1114 KIFIHVAGDMSFPADISGAVSVVNHIDEILDRYIKEKELFPQVPPHDFAAMEQIKLDLMQ 1173
                    + S  + +    +V   +D I D   K ++L       + + + + ++    
Sbjct: 1242 --------NYSLHSQLCEKFNVQESLDSIDDLIEKFEKLSSSEKNDNLSNLIERQI---- 1289

Query: 1174 LHKRWQAIFLWQDGSLVQAMKNGDLFLIDEISLADDSVLERLNSVLEPERKLSLAEKGGS 1233
               +++++F W DG+LV AMK GD FL+DEISLADDSVLERLNSVLE  R L+L E   +
Sbjct: 1290 --IKYRSLFEWHDGALVTAMKQGDFFLLDEISLADDSVLERLNSVLELSRTLTLVEHSNA 1347

Query: 1234 VLEKVVAHPNFFILATMNPGGDYGKKELSPALRNRFTEVWVPAVTNVDELKSIAIERFTN 1293
             +  + A   F   ATMNPGGDYGKKELSPALRNRFTE+WVP + + +++  I   +  N
Sbjct: 1348 AV-SLTAKDGFAFFATMNPGGDYGKKELSPALRNRFTEIWVPPMVDTEDILKIVEGKLHN 1406

Query: 1294 AEVSCFGDCIVNFWMWF-NQLHTGRMLTIRDLLSWISFINVTE---RNLGPQQAXXXXXX 1349
             ++      +V +  W  N+     +++IRD+LS + FIN  E    NL    A      
Sbjct: 1407 NKIE-LARPLVEYAKWHANEYLYTDVISIRDVLSAVEFINACEILDLNLVLFNAVSMVFI 1465

Query: 1350 XXXXXXXXXXMNVSKTEATELRRTCLSFLLEELQKVEGKPLNSDLHDLKNYGWGDHTREI 1409
                      ++ +       R+ C +    +L ++ G  +               + +I
Sbjct: 1466 DALGSFTTFSLSNNLASLHAERQRCFA----KLNELAGSNI-----------MASKSADI 1510

Query: 1410 DIGQPD-HFGIMPFYIDTGHFTRKQQGFQFMAPTTSKNVFRVLRGMQLPKPLLLEGSPGV 1468
             I   D  F I  F I  G        +     TT  N  +VLR +Q+ KP+LLEGSPGV
Sbjct: 1511 SIKFSDSSFFIGDFGIPLGDSVESDSTYSLHTDTTLMNASKVLRALQVLKPILLEGSPGV 1570

Query: 1469 GKTSLIVALAGFSGHNVVRINLSEQTDMMDLLGSDLPVEGENGMEFAWSDGILLQALKNG 1528
            GKTSLI ALA  +GH +VRINLS+QTD+MDL GSD+PVEG  G +FAW D   L A++NG
Sbjct: 1571 GKTSLITALARETGHQLVRINLSDQTDLMDLFGSDVPVEGGEGGQFAWRDAPFLAAMRNG 1630

Query: 1529 SWVLLDELNLAPQSVLEGLNAILDHRAEVFIPELGQTYKCPPSFRVFACQNPSSQGGGRK 1588
             WVLLDELNLA QSVLEGLNA LDHR E +IPEL + +K  P+FRVFA QNP  QGGGRK
Sbjct: 1631 HWVLLDELNLASQSVLEGLNACLDHRNEAYIPELDKVFKAHPNFRVFAAQNPQHQGGGRK 1690

Query: 1589 GLPKSFLNRFTKVYVDELSESDYSFICKSQYPSIKDDILKKLISFNNRLYMDTMIHKKYG 1648
            GLP+SF+NRF+ VYV+ L E D   I    Y  + +D   K+I F  RL  +      +G
Sbjct: 1691 GLPRSFINRFSVVYVEALKEKDMIEIAACNYHQVNEDWRLKIIKFMFRLQDNIEKDISFG 1750

Query: 1649 QEGSPWEFNLRDIIRSCEMIVGACETARGYPETSMVDCFLNTVYLQRMRTVADREEVVKL 1708
              GSPWEFNLRD +R  +++      A  Y   S  D +L  + L RMRTV DR    +L
Sbjct: 1751 SFGSPWEFNLRDTLRWLQLL----NDAPKYTCVSPAD-YLEVMVLHRMRTVEDRVRTCEL 1805

Query: 1709 FEEVFQTKYSIHEIKMLYVNPQCLVVGSASIRRNRVHSCKVQNSQLNILPGTLHSLEAAM 1768
            F+EVF   Y    I    ++ QC  VG + + R+      + +SQ NIL   L  LE+ +
Sbjct: 1806 FKEVFDIDYEPRTIG-FSLSSQCFKVGHSLLVRDVERQKTLLDSQ-NILQSQLPVLESVI 1863

Query: 1769 HCINQGWLCILVGQHSSGKTSLIRLLAQLSGNTLNEVNLSSATDVSELLGCFEQYNFFRH 1828
             CIN+ W CILVG  ++GKT ++RLLA ++G  + E+ ++S TD  +L+G +EQ +    
Sbjct: 1864 TCINKKWPCILVGDTATGKTCILRLLAAIAGAKIKEMAVNSDTDTMDLIGEYEQID---- 1919

Query: 1829 YKVVISQVERYIDEYFS-LSQYIQWKSLVADRKTLFVKWFEFVIAKKFSSICISTLVEMS 1887
                   + R   E F+ LSQ +           + +K+  F     F    + TL   S
Sbjct: 1920 -------ISRKASELFTDLSQQLL---------NIVIKYRNF--DNIFRETSLYTLTTTS 1961

Query: 1888 KNSSLPSLSLVRDIVEDMKCDMEMFDLPVSFNKDDLSKTLRSIYYLQQSEAVHQPV-KFE 1946
              +   + +L++ +V+ +  D       +  +  D+ +  R +     +E    P  +FE
Sbjct: 1962 FKTHSQAFTLLQKVVDQL--DQLKIHETLVHSLGDIHEKARKLL----AEFSASPAGRFE 2015

Query: 1947 WVAGDLIRAIECGEWIVLDNANFCNPTVLDRINSLVEQERSIVVNECGLVDGNPVILKAH 2006
            W  G L++A+E G W VLDNAN C+P VLDR+NSL+E +  ++VNE    DG+P  +K H
Sbjct: 2016 WFDGYLLKAVEEGHWFVLDNANLCSPAVLDRLNSLLEHKGVLIVNEKTTEDGHPKTIKPH 2075

Query: 2007 PKFRMFLTINAKHGEVSRAMRNRGVEIFLMNQNLS 2041
            P FR+FLT+N  +GE+SRAMRNRGVEIFL+ + L+
Sbjct: 2076 PNFRLFLTVNPVYGELSRAMRNRGVEIFLLKEALT 2110



 Score =  335 bits (860), Expect = 3e-90,   Method: Compositional matrix adjust.
 Identities = 359/1355 (26%), Positives = 609/1355 (44%), Gaps = 214/1355 (15%)

Query: 7    WPILLYGPVGAGKTALINKLAQIGGNRVLFIHMDEQMDGRTLIGSYVCTEKPGEFKWSPG 66
            +PIL+ GP  +GKT++I  +A+  G++ + I+  E  D +  IG+YV T+  G   +  G
Sbjct: 895  FPILIQGPTSSGKTSMIEYVAKKTGHKFVRINNHEHTDLQEYIGTYV-TDDNGSLSFREG 953

Query: 67   SLTQAVIKGFWIVFEDIDKAPSDVQSILLPLLEGSSSFSVGHAEA-VEVAENFRLFAT-- 123
             L +A+  G+WIV ++++ AP+DV   L  LL+ +    +   +  V+    F LFAT  
Sbjct: 954  VLVEALRNGYWIVLDELNLAPTDVLEALNRLLDDNRELFIPETQVLVKPHPEFMLFATQN 1013

Query: 124  ---VTTSKNDVSHALEGRLTFSALWRKVMVGEPNRKDMIDIIHGCYPSLESISAKLIDTF 180
               V   +  +S A   R      + ++   +    ++  I+H       S +AK++  F
Sbjct: 1014 PPGVYAGRKHLSRAFRNR------FLEIHFDDIPENELETILHKRCKIAPSYAAKIVQVF 1067

Query: 181  EKANLLVSYQFGGLNLAGGSSECLVQRFS---LRDLLKWCKRIRGVDLNFKGLGLSSSCC 237
             +           L+L   ++    Q+ S   LRDL +W  R        + +G      
Sbjct: 1068 RE-----------LSLRRQTTRIFEQKNSFATLRDLFRWAFR--------EAVGYQQ--- 1105

Query: 238  KLIYFEAVDIFASSLSSLDKRLYVAREIAKLFCVPHGAETISPSDKPIIQARHTDLQVGR 297
              +      + A        +L V   I K+  V    + I   D   I     D+    
Sbjct: 1106 --LAENGYMLLAERARDQKDKLAVQEVIEKVMKVKIDTDGIYNLDSMEI---FQDMS--- 1157

Query: 298  VTLQCSDKPALIQKGPFADI---RRALEVLERVACSIKFNEPVLLVGETGTGKTTLVQNL 354
                       +++GP + +   R  + +   V   +   EPVLLVG+TG GKTT+ Q L
Sbjct: 1158 -----------LKEGPLSKVVWTRPMIRLFCLVWRCLLAKEPVLLVGDTGCGKTTVCQIL 1206

Query: 355  ASWLKQPLTVVNLSQQSDISDLLGGFKPADARS-ICFPLYIEFKDLFCRSFSGKDNEAIL 413
            A  L + L ++N  Q ++  D++G  +P   RS + + L+ +     C  F+ +++    
Sbjct: 1207 AECLHKELHIINAHQDTENGDIIGAQRPVRNRSAVNYSLHSQL----CEKFNVQES---- 1258

Query: 414  RHCDVYVMEKKWKKLLRALEKCVEKAQKLIDXXXXXXXXXXXXXPLPAQVISDWDSFSSR 473
                           L +++  +EK +KL                         D+ S+ 
Sbjct: 1259 ---------------LDSIDDLIEKFEKLSSSEKN-------------------DNLSNL 1284

Query: 474  LNAACSQIGSEIGMSFQFVEGAFVSALRNGHWILLDEVNLAPPETLQRIGAVLDGESGTL 533
            +     +  S     F++ +GA V+A++ G + LLDE++LA    L+R+ +VL+  S TL
Sbjct: 1285 IERQIIKYRS----LFEWHDGALVTAMKQGDFFLLDEISLADDSVLERLNSVLEL-SRTL 1339

Query: 534  CLAERGDVDY-IERHPCFRMFACMNPATDAGKRELPYTFRSRFTEFFVXXXXXXXXXXXF 592
             L E  +    +     F  FA MNP  D GK+EL    R+RFTE +V            
Sbjct: 1340 TLVEHSNAAVSLTAKDGFAFFATMNPGGDYGKKELSPALRNRFTEIWVPPMVDTED---- 1395

Query: 593  VSKYLDG-LHAAK-GVADSIVRFYKAAKKESEEKLQDGANQKPQFSLRSLSRSLGYIKNA 650
            + K ++G LH  K  +A  +V +   AK  + E L          S+R +  ++ +I NA
Sbjct: 1396 ILKIVEGKLHNNKIELARPLVEY---AKWHANEYLYTDV-----ISIRDVLSAVEFI-NA 1446

Query: 651  ERKFGFKKALYDGFCMFFLTMLDAPSAKIINNLIVSL-------------------LLDG 691
                     L++   M F+  L + +   ++N + SL                   +   
Sbjct: 1447 CEILDLNLVLFNAVSMVFIDALGSFTTFSLSNNLASLHAERQRCFAKLNELAGSNIMASK 1506

Query: 692  RVPPRISFAD--YFVEK--PKLLNGSESDDFLRSYVL-TNSVTEHIVNLACAVYIKKYPV 746
                 I F+D  +F+      L +  ESD    +Y L T++   +   +  A+ + K P+
Sbjct: 1507 SADISIKFSDSSFFIGDFGIPLGDSVESDS---TYSLHTDTTLMNASKVLRALQVLK-PI 1562

Query: 747  LLQGPTSSGKTSLVRFLAAQTGHEFVRINNHEHTDLQEYLGTYVT---DSHGKLQFQEGA 803
            LL+G    GKTSL+  LA +TGH+ VRIN  + TDL +  G+ V       G+  +++  
Sbjct: 1563 LLEGSPGVGKTSLITALARETGHQLVRINLSDQTDLMDLFGSDVPVEGGEGGQFAWRDAP 1622

Query: 804  LVKAVREGHWIVLDELNLAPSDVLEALNRLLDDNRELFVPELQETIPAHPNFMLFATQNP 863
             + A+R GHW++LDELNLA   VLE LN  LD   E ++PEL +   AHPNF +FA QNP
Sbjct: 1623 FLAAMRNGHWVLLDELNLASQSVLEGLNACLDHRNEAYIPELDKVFKAHPNFRVFAAQNP 1682

Query: 864  PVLYGGRKILSRAFRNRFIEVHVDEIPEDELITILEQRCSIACSY-------ATRMVQVM 916
                GGRK L R+F NRF  V+V+ + E ++I I       AC+Y         ++++ M
Sbjct: 1683 QHQGGGRKGLPRSFINRFSVVYVEALKEKDMIEI------AACNYHQVNEDWRLKIIKFM 1736

Query: 917  KDLQTHRQNSRVFAGKHGFITP-----RDLFRWANRYRLFEGKSYEDLAKDGYL--LLAE 969
              LQ + +    F     F +P     RD  RW     L +   Y  ++   YL  ++  
Sbjct: 1737 FRLQDNIEKDISFG---SFGSPWEFNLRDTLRWLQ--LLNDAPKYTCVSPADYLEVMVLH 1791

Query: 970  RLRDDTEKAVVQEVLERHLHVKLSISNL-YNMEVSC----DNNLSRESIRLRVQETFGNI 1024
            R+R   ++    E+ +    +      + +++   C     + L R+  R +      NI
Sbjct: 1792 RMRTVEDRVRTCELFKEVFDIDYEPRTIGFSLSSQCFKVGHSLLVRDVERQKTLLDSQNI 1851

Query: 1025 TWTESMWRLYFLIERCYRSREPVLLVGETGGGKTTVCQVLSAVLGVKLHILNCHQYTETS 1084
               +S   +   +  C   + P +LVG+T  GKT + ++L+A+ G K+  +  +  T+T 
Sbjct: 1852 --LQSQLPVLESVITCINKKWPCILVGDTATGKTCILRLLAAIAGAKIKEMAVNSDTDTM 1909

Query: 1085 DFIGGFCPIRDRSKIAMEF-----KHLITKMKQLKIFIHVAGDMSFPADI-------SGA 1132
            D IG +  I D S+ A E      + L+  + + + F ++  + S            S A
Sbjct: 1910 DLIGEYEQI-DISRKASELFTDLSQQLLNIVIKYRNFDNIFRETSLYTLTTTSFKTHSQA 1968

Query: 1133 VSVVNHIDEILDRYIKEKELFPQVPPHDFAAM-EQIKLDLMQLHKRWQAIFLWQDGSLVQ 1191
             +++  + + LD+    + L      H    + E+ +  L +        F W DG L++
Sbjct: 1969 FTLLQKVVDQLDQLKIHETLV-----HSLGDIHEKARKLLAEFSASPAGRFEWFDGYLLK 2023

Query: 1192 AMKNGDLFLIDEISLADDSVLERLNSVLEPERKLSLAEKGG--SVLEKVVAHPNFFILAT 1249
            A++ G  F++D  +L   +VL+RLNS+LE +  L + EK       + +  HPNF +  T
Sbjct: 2024 AVEEGHWFVLDNANLCSPAVLDRLNSLLEHKGVLIVNEKTTEDGHPKTIKPHPNFRLFLT 2083

Query: 1250 MNPGGDYGKKELSPALRNRFTEVWV--PAVTNVDE 1282
            +NP   YG  ELS A+RNR  E+++   A+T +D+
Sbjct: 2084 VNPV--YG--ELSRAMRNRGVEIFLLKEALTEIDK 2114



 Score =  290 bits (743), Expect = 1e-76,   Method: Compositional matrix adjust.
 Identities = 267/914 (29%), Positives = 448/914 (49%), Gaps = 94/914 (10%)

Query: 4171 EGILSELLEAHRTTSEMTHALGDLLIHLFAEGFGSTDDTTEDASDGPQQDAXXXXXXXXX 4230
            E +L   +  H +  +    +  L   +   GF S D   E  S+  + ++         
Sbjct: 3860 ESVLDYFINVHNSNLDSLSKISTLFFMVANNGFCSPDLPQEGKSNSGELESGTGLGSGVG 3919

Query: 4231 XKESASSKIDDISQLEGTANEMDALRKPDQAPKNDDDAVEMQDDFNAELSDVSEDPEGND 4290
              E  ++ +++   LE  ANE D     +Q+  ++ +A E++ D N    D S   E  +
Sbjct: 3920 A-EDITNTLNEDDDLEELANEEDT---ANQSDLDESEARELESDMNGVTKD-SVVSENEN 3974

Query: 4291 SGDEDDDTNLENQMGDTG-DASEMVGKKSWDKDEDDDPNRSTEKYESGSSAKETQKNDRE 4349
            S  E+++ +L+ ++ D   D S  + +K WD+  ++D   + +K    S+A     N+ +
Sbjct: 3975 SDSEEENQDLDEEVNDIPEDLSNSLNEKLWDEPNEEDLLETEQKSNEQSAAN----NESD 4030

Query: 4350 LRAK--DEGALEEDPMETDCDEQGKNNNL----EDDPSTCEDVDQDTNDLMDKADAYDDR 4403
            L +K  D  ALE+   +   DE+  ++++    E  P   E+  Q   +  D  D  +D 
Sbjct: 4031 LVSKEDDNKALEDKDRQEKEDEEEMSDDVGIDDEIQPDIQENNSQPPPENEDHLDLPEDL 4090

Query: 4404 TAPELP---EPKDDSEDVDMDGT-EHIDEMDADGEE-LSPEEEKLAADGCLXXXXXXXXX 4458
               E         D ED+DM+   E+ +E DA+ +E +   E+ L  +  L         
Sbjct: 4091 KLDEKEGDVSKDSDLEDMDMEAADENKEEADAEKDEPMQDFEDPLEENNTLDEDIQQDDF 4150

Query: 4459 XXXQHGDNEI--DGEQEHAEDGQMETNNMEKELHNIESLEHPSQGIQPNNAEMDYNRESE 4516
                  D ++  DG +E+ ++ +  T +  K    +E  E P      N+ +MD      
Sbjct: 4151 SDLAEDDEKMNEDGFEENVQENEESTEDGVKSDEELEQGEVPEDQAIDNHPKMDAKSTFA 4210

Query: 4517 SNLANSTDMNSAAAPSVNFSSNEVPSLEISMPNSGDGSRLLSNSKPELQ----TDTPPSQ 4572
            S  A+  + +            E  + E  +  +G      S+++ ++Q    T TP   
Sbjct: 4211 SAEADEENTDKGIVGENEELGEEDGAAESGVRGNGTADGEFSSAE-QVQKGEDTSTPKEA 4269

Query: 4573 IKQTN-PFRSIGDAMADWKERAKVSA--DTQDHQPEAEHHIDDESATEFRYVPDSEQSTS 4629
            + + +  ++S+GD + +W++  ++    D  + Q +A    DD   +EF +V + E+   
Sbjct: 4270 MSEADRQYQSLGDHLREWQQANRIHEWEDLTESQSQA---FDD---SEFMHVKEDEEEDL 4323

Query: 4630 QALGNATADQINDDLQVKQSSMEDENRVQKEEHNTDRAPGDDHNLEVPHLQASQSRTNKS 4689
            QALGNA  DQI                      + DR    + N +      S + TN +
Sbjct: 4324 QALGNAEKDQIK---------------------SIDRDESANQNPD------SMNSTNIA 4356

Query: 4690 EN-ANNLEHREIQTDTYVQDSVQGETDETFGDFVSFKQPPADEKTVMRDDLANDRELSTP 4748
            E+ A+ +  +++Q    + D  Q   D    +F S  Q    EK     +L+ D ++   
Sbjct: 4357 EDEADEVGDKQLQDGQDISDIKQTGEDTLPTEFGSINQ---SEKVF---ELSEDEDIEDE 4410

Query: 4749 M---EINITDVDMKGPIVD----WKSVELTTMKLSQELAEQLRLVMEPTLASKLQGDYRT 4801
            +    + IT++    PI +    W   E +T +LS EL EQLRL++EPTLA+K+QGD+RT
Sbjct: 4411 LPDYNVKITNLPAAMPIDEARDLWNKHEDSTKQLSIELCEQLRLILEPTLATKMQGDFRT 4470

Query: 4802 GKRINMKKVIPYIASHFRRDKIWLRRTKPNKRNYQVVIAVDDSRSMSEGKCGKVAIEALV 4861
            GKR+NMK++IPYIAS F++DKIW+RR KP+KR YQV+I++DDS+SMSE     +A+E L 
Sbjct: 4471 GKRLNMKRIIPYIASQFKKDKIWMRRVKPSKRTYQVMISIDDSKSMSESGSTVLALETLA 4530

Query: 4862 TVCRAMSQLEVGQFAVASFGKKGNVKVLHDFDQVFNGEAGTNMISSLSFEQDNKLEDEPV 4921
             V +A+S LEVGQ AV  FG++   ++LH FD+ F+ E+G  M S  +FEQ N      +
Sbjct: 4531 LVTKALSLLEVGQIAVMKFGEQP--ELLHPFDKQFSSESGVQMFSHFTFEQSNT-NVLAL 4587

Query: 4922 ADLLMHLNTMLDTAVARSRTPSGQNPLQQLVLIISDGKFHEKENLKRCVRNVLNRKRMIA 4981
            AD  M      +TA +  R+ S    ++QL +IISDG   + +++++ +R     K MI 
Sbjct: 4588 ADASMKCFNYANTA-SHHRSNSD---IRQLEIIISDGICEDHDSIRKLLRRAQEEKVMIV 4643

Query: 4982 YVLLDG----HEESIMDSLEVSY----QGT-KLTMGKYMDSFPFPYYVMLKNIEALPRTL 5032
            +V+LD      + SI+D  +V Y     GT  L +  Y+D F F YY++++NIE LP+ L
Sbjct: 4644 FVILDNVNTQKKSSILDIKKVYYDTKEDGTMDLKIQPYIDEFAFDYYLVVRNIEELPQLL 4703

Query: 5033 ADLLRQWFELMQSA 5046
            +  LRQWF+ M + 
Sbjct: 4704 SSALRQWFQQMSNT 4717



 Score =  283 bits (725), Expect = 2e-74,   Method: Compositional matrix adjust.
 Identities = 311/1180 (26%), Positives = 534/1180 (45%), Gaps = 160/1180 (13%)

Query: 721  SYVLTNSVTEHIVNLACAVYIKKYPVLLQGPTSSGKTSLVRFLAAQTGHEFVRINNHEHT 780
            S VLT S  E++ N      ++K P+LL GP   GK  L+  +AA+ G + +RI+  + T
Sbjct: 131  SLVLTKSTQENL-NRITPYLVQKRPILLAGPEGIGKKFLITQIAAKLGQQIIRIHLSDST 189

Query: 781  DLQEYLGTYVTDSHGKLQFQEGALVKAVREGHWIVLDELNLAPSDVLEALNRLLDDNREL 840
            D +  +GTY +   G+ ++Q G L +AV  G WI+   +  APS+VL  L  LL + R+L
Sbjct: 190  DPKMLIGTYTSPKPGEFEWQPGVLTQAVITGKWILFTNIEHAPSEVLSVLLPLL-EKRQL 248

Query: 841  FVPELQETIPAHPNFMLFATQNPPVLYGGRK---ILSRAFRNRFIEVHVDEIPED--ELI 895
             +P   ETI A  +F +FAT +      G++   IL   ++           P++  E++
Sbjct: 249  VIPSRGETIYAKGSFQMFATSSMKTKILGQRLWQILDLTYQ-----------PDECVEVV 297

Query: 896  TILEQRCSIACSYATRMVQVMKDLQTHRQ---NSRVFAGKHGFITPRDLFRWANRYRLFE 952
            + L    SI C     + + + DL + R     S+++      +  RD +++  R     
Sbjct: 298  STLYPVLSIICPTLYSVYKDIFDLFSQRSFLATSKIYRR----LCLRDFYKFIKRVAFLY 353

Query: 953  GKSYEDLAKDGYLLLAERLRD-----------------DTEKAVVQEVL-------ERHL 988
             K    +    ++++++ L+D                 D    VV+ V        E+ L
Sbjct: 354  HKF---MIPSDHVVISQELQDAVFKEAIDMFGAFIPSRDGFDLVVRNVAIELNIPPEKAL 410

Query: 989  HVKLSISNLYNMEVSCDNNLSRESIR----LRVQETFGNITWTESMWRLYFLIERCYRSR 1044
             ++ SI    N+E +   N+ R S++    +R   T  +  +T S   L   +    ++ 
Sbjct: 411  QLRYSIPVFQNLEHNI--NIGRCSLKKLSTIRSCST-NSYAFTSSSLGLLEQLAAGVQTN 467

Query: 1045 EPVLLVGETGGGKTTVCQVLSAVLGVKLHILNCHQYTETSDFIGGFCPIRDRSKIAME-- 1102
            EP+LLVGETG GKTT  Q+L+ +LG K+ ++N  Q TE+SD +GG+ PI + S + +   
Sbjct: 468  EPLLLVGETGTGKTTTIQLLAGLLGQKVTVINMSQQTESSDMLGGYKPI-NASTLGLPLH 526

Query: 1103 ------FKHLITKMKQLKIFIHVAGDMS-----------FPADISGAVSVVNHIDEILDR 1145
                  F+   +  K  K FI +A   +           +      + +V++    + + 
Sbjct: 527  ERFIDIFEQTFSSKKNAK-FISMASTSARRFRWKTCLKIWKEACKLSKTVLDGQQPLPNP 585

Query: 1146 YIKEKELFPQVPPHD-FAAMEQIKLDLMQLHKRWQAIFLWQ--DGSLVQAMKNGDLFLID 1202
              ++K L  QV   + +A  E+   D  ++       F++   +G+LV+A+++G   L+D
Sbjct: 586  QKRQKRLSNQVELRNQWAKFEKEVEDFEKVLTGGSNGFMFSFVEGALVKAVRSGHWVLLD 645

Query: 1203 EISLADDSVLERLNSVLEP-ERKLSLAEKGGSVLEKVVAHPNFFILATMNPGGDYGKKEL 1261
            EI+LA    LE +  +L   E  + L+E+G   +  +  H NF +   MNP  D GK+EL
Sbjct: 646  EINLASLETLEPIGQLLSSYESGILLSERGD--ITPITPHKNFRLFGCMNPSTDVGKREL 703

Query: 1262 SPALRNRFTEVWVPAV-TNVDELKSIAIERFTNAEVSCFGD-----CIVNFWMWFNQLHT 1315
             P+ R+RFTE++V +   N+D+L SI I+++  +   C G+      +   +     L  
Sbjct: 704  EPSFRSRFTEIYVHSPDQNLDDLLSI-IQKYIGS--LCIGNEHVIREVAELYQVAKSLSL 760

Query: 1316 GRML----------TIRDLLSWISFINVT------ERNLGPQQAXXXXXXXXXXXXXXXX 1359
               L          T+R L   +S++          R+L                     
Sbjct: 761  DGSLVDGAGQRPHYTVRTLSRTLSYVTEIAPIYGLRRSLYEGFCMSFLTLLDHTSESLLY 820

Query: 1360 MNVSKTEATELRRTCLSFLLEELQKVEGKPLNSDLHDLKNYGWGDHTREIDIGQPDHFGI 1419
             +V +    EL R   + +L+++ KV   P +S      +Y W        + + +H+ I
Sbjct: 821  NHVVRFTLGELNRDQQNAILKQIPKV---PDHSSYIAFCHY-WL-RRGSFPVEEQEHYII 875

Query: 1420 MPFYIDTGHFTRKQQGFQFMAPTTSKNVFRVLRGMQLPKPLLLEGSPGVGKTSLIVALAG 1479
             PF          Q+    +A   S  +F          P+L++G    GKTS+I  +A 
Sbjct: 876  TPFV---------QKNLLNIARACSTRMF----------PILIQGPTSSGKTSMIEYVAK 916

Query: 1480 FSGHNVVRINLSEQTDMMDLLGSDLPVEGENGMEFAWSDGILLQALKNGSWVLLDELNLA 1539
             +GH  VRIN  E TD+ + +G+   V  +NG   ++ +G+L++AL+NG W++LDELNLA
Sbjct: 917  KTGHKFVRINNHEHTDLQEYIGT--YVTDDNG-SLSFREGVLVEALRNGYWIVLDELNLA 973

Query: 1540 PQSVLEGLNAILDHRAEVFIPELGQTYKCPPSFRVFACQNPSSQGGGRKGLPKSFLNRFT 1599
            P  VLE LN +LD   E+FIPE     K  P F +FA QNP     GRK L ++F NRF 
Sbjct: 974  PTDVLEALNRLLDDNRELFIPETQVLVKPHPEFMLFATQNPPGVYAGRKHLSRAFRNRFL 1033

Query: 1600 KVYVDELSESDYSFICKSQYPSIKDDILKKLISFNNRLYMDTMIHKKYGQEGSPWEFNLR 1659
            +++ D++ E++   I   +   I      K++     L +     + + Q+ S     LR
Sbjct: 1034 EIHFDDIPENELETILHKRC-KIAPSYAAKIVQVFRELSLRRQTTRIFEQKNSFA--TLR 1090

Query: 1660 DIIRSCEMIVGACETARGYPETSMVDCFLNTVYLQRMRTVADREEVVKLFEEVFQTKYSI 1719
            D+ R       A   A GY + +     L     +R R   D+  V ++ E+V + K   
Sbjct: 1091 DLFR------WAFREAVGYQQLAENGYML---LAERARDQKDKLAVQEVIEKVMKVKIDT 1141

Query: 1720 HEIKMLYVNPQCLVVGSASIRRNRVHSCKVQNSQLNILPGTLHSLEAAMHCINQGWLCIL 1779
              I   Y      +    S++   +         + +             C+      +L
Sbjct: 1142 DGI---YNLDSMEIFQDMSLKEGPLSKVVWTRPMIRLFC-------LVWRCLLAKEPVLL 1191

Query: 1780 VGQHSSGKTSLIRLLAQLSGNTLNEVNLSSATDVSELLGC 1819
            VG    GKT++ ++LA+     L+ +N    T+  +++G 
Sbjct: 1192 VGDTGCGKTTVCQILAECLHKELHIINAHQDTENGDIIGA 1231



 Score = 60.8 bits (146), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 64/296 (21%), Positives = 125/296 (42%), Gaps = 22/296 (7%)

Query: 3351 RQTCAPSLECNTYNAYKDPNPSILFKMVEPLTALQEKVRYFLDEWPGHPGLLKILDIITS 3410
            RQ   P +    YN Y DPNPS   ++ + +  ++ +    +  WP +  L  + D I +
Sbjct: 3117 RQYWTPPV----YNFYSDPNPSKAIEVRDLIKIVESRAISLIKNWPENFVLRGLKDAIDA 3172

Query: 3411 LLAI-PLSTPXXXXXXXXXXXXXXAQTLQENDSKFFLKDHLPQLFIIVSSWQRLELECWP 3469
            +L + P S                ++  +    ++ L + +  +   +  W++ EL  W 
Sbjct: 3173 ILNLSPFSPIAEYLSKLERVFHLLSEWEKLASREYSLANEMDLIKKKIIDWRKFELSNWN 3232

Query: 3470 ILLQEVLEKY---ESNALKLWFPLRALLT----QSCDXXXXXXXXXXXXXXXFVQTSSIG 3522
             LL+  LE+Y   E    +L+  L+ ++     ++                 F+   ++G
Sbjct: 3233 NLLK--LEEYKLSERVYPRLYSILQFIILKPFFENSKFTKQNLCESASIIVQFITDLTVG 3290

Query: 3523 EFKRRLHLLLAFHGELSDGAGVGAYSSNSLKKIQNILYNMFGYYMQFLPLVLXXXXXXXX 3582
            EF+  L  LL+F           A S      I  +L N++ Y+ QFL  V         
Sbjct: 3291 EFQLCLKCLLSFSQH--------AASLRICHGIDAMLLNIYHYFEQFLSKVSEAIHTQKQ 3342

Query: 3583 XXXXDLKDQVKLYRWEQDPHSASIENFKRTRQKVFKLLQCFNDILQKPVMVLLNQE 3638
                 +K+++ L  W+     A  E+ K++  ++FK+L  + ++L++PV   L+Q+
Sbjct: 3343 SLENSIKERILLMSWKDTNVYALKESAKKSHAELFKVLHRYREVLRQPVSSYLSQK 3398

Query: CNT0024955
Subject: sp|Q9NU22|MDN1_HUMAN Midasin OS=Homo sapiens GN=MDN1 PE=1 SV=2
204508 / S288c) GN=MDN1 PE=1 SV=1

 Score = 1328 bits (3438), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 768/1913 (40%), Positives = 1096/1913 (57%), Gaps = 175/1913 (9%)

Query: 8    PILLYGPVGAGKTALINKLAQIGG--NRVLFIHMDEQMDGRTLIGSYVCTEKPGEFKWSP 65
            PI+L G  G+GKT LIN+L++  G  + ++ IH+ EQ D + LIG+Y   +KPG F+W  
Sbjct: 310  PIMLIGKAGSGKTFLINELSKYMGCHDSIVKIHLGEQTDAKLLIGTYTSGDKPGTFEWRA 369

Query: 66   GSLTQAVIKGFWIVFEDIDKAPSDVQSILLPLLEGSSSFSVGHAEAVEVAENFRLFATVT 125
            G L  AV +G W++ EDIDKAP+DV SILL LLE          E V+ A  F+L +TV 
Sbjct: 370  GVLATAVKEGRWVLIEDIDKAPTDVLSILLSLLEKRELTIPSRGETVKAANGFQLISTVR 429

Query: 126  TSKN---DVSHALEG-RLTFSALWRKVMVGEPNRKDMIDIIHGCYPSLESISAKLIDTFE 181
             +++   D S+ +    +    +W  + + EP+ +D+  I+   +P L ++  KLID+++
Sbjct: 430  INEDHQKDSSNKIYNLNMIGMRIWNVIELEEPSEEDLTHILAQKFPILTNLIPKLIDSYK 489

Query: 182  KA-NLLVSYQFGGLNLAGGSSECLVQRFSLRDLLKWCKRIRGVDLNFKGLGLS------- 233
               ++ ++ +F  LN  G  +  +    S+RDL+K C+R+   D+ FK  G++       
Sbjct: 490  NVKSIYMNTKFISLN-KGAHTRVV----SVRDLIKLCERL---DILFKNNGINKPDQLIQ 541

Query: 234  SSCCKLIYFEAVDIFASSLS----------SLDKRLYVAREIAKLFCVPHGAETISPSDK 283
            SS    I+ EA D FA ++           ++ + L +A     LF   H          
Sbjct: 542  SSVYDSIFSEAADCFAGAIGEFKALEPIIQAIGESLDIASSRISLFLTQH---------V 592

Query: 284  PIIQARHTDLQVGRVTL---QCSDKPALIQKGPFADIRRALEVLERVACSIKFNEPVLLV 340
            P ++     +++GR  L   + + +   +    FA    +L ++E+++  I+  EPVLLV
Sbjct: 593  PTLENLDDSIKIGRAVLLKEKLNIQKKSMNSTLFAFTNHSLRLMEQISVCIQMTEPVLLV 652

Query: 341  GETGTGKTTLVQNLASWLKQPLTVVNLSQQSDISDLLGGFKPADARSICFPLYIEFKDLF 400
            GETGTGKTT+VQ LA  L + LTV+N+SQQ++  DLLGG+KP +++++  P+   F+ LF
Sbjct: 653  GETGTGKTTVVQQLAKMLAKKLTVINVSQQTETGDLLGGYKPVNSKTVAVPIQENFETLF 712

Query: 401  CRSFSGKDNEAILRHCDVYVMEKKWKKLLRALEKCVEKAQ---KLIDXXXXXXXXXXXXX 457
              +FS K NE   +       + +WK +++   +  + AQ   K+ +             
Sbjct: 713  NATFSLKKNEKFHKMLHRCFNKNQWKNVVKLWNEAYKMAQSILKITNTENENENAKKKKR 772

Query: 458  PLPAQ----VISDWDSFSSRLNAACSQIGS-EIGMSFQFVEGAFVSALRNGHWILLDEVN 512
             L       ++  W  F+  +    +Q  S E    F FVEG+ V  +R G W+LLDEVN
Sbjct: 773  RLNTHEKKLLLDKWADFNDSVKKFEAQSSSIENSFVFNFVEGSLVKTIRAGEWLLLDEVN 832

Query: 513  LAPPETLQRIGAVL-DGESGTLCLAERGDVDYIERHPCFRMFACMNPATDAGKRELPYTF 571
            LA  +TL+ I  +L + +S ++ L+E+GD + I+ HP FR+FACMNPATD GKR+LP   
Sbjct: 833  LATADTLESISDLLTEPDSRSILLSEKGDAEPIKAHPDFRIFACMNPATDVGKRDLPMGI 892

Query: 572  RSRFTEFFVXX-XXXXXXXXXFVSKYLDGLHAA-KGVADSIVRFYKAAKKESEEK-LQDG 628
            RSRFTE +V             + KY+     + + V + I   Y  AKK S+   + DG
Sbjct: 893  RSRFTEIYVHSPERDITDLLSIIDKYIGKYSVSDEWVGNDIAELYLEAKKLSDNNTIVDG 952

Query: 629  ANQKPQFSLRSLSRSLGYIKNAERKFGFKKALYDGFCMFFLTMLDAPSAKIINNLIVSLL 688
            +NQKP FS+R+L+R+L Y+ +    +G +++LYDGFCM FLT+LD  S  I+  +I    
Sbjct: 953  SNQKPHFSIRTLTRTLLYVTDIIHIYGLRRSLYDGFCMSFLTLLDQKSEAILKPVIEKFT 1012

Query: 689  LDGRV---------------PPRISFADYFVEKPKLLNGSESDDFLRSYVLTNSVTEHIV 733
            L GR+               P  + F  Y+++K     G  +      Y++T  V ++++
Sbjct: 1013 L-GRLKNVKSIMSQTPPSPGPDYVQFKHYWMKK-----GPNTIQEQAHYIITPFVEKNMM 1066

Query: 734  NLACAVYIKKYPVLLQGPTSSGKTSLVRFLAAQTGHEFVRINNHEHTDLQEYLGTYVTDS 793
            NL  A   K++PVL+QGPTSSGKTS++++LA  TGH+FVRINNHEHTDLQEYLGTYVTD 
Sbjct: 1067 NLVRATSGKRFPVLIQGPTSSGKTSMIKYLADITGHKFVRINNHEHTDLQEYLGTYVTDD 1126

Query: 794  HGKLQFQEGALVKAVREGHWIVLDELNLAPSDVLEALNRLLDDNRELFVPELQETIPAHP 853
             GKL F+EG LV+A+R+G+WIVLDELNLAP+DVLEALNRLLDDNRELF+PE QE +  HP
Sbjct: 1127 TGKLSFKEGVLVEALRKGYWIVLDELNLAPTDVLEALNRLLDDNRELFIPETQEVVHPHP 1186

Query: 854  NFMLFATQNPPVLYGGRKILSRAFRNRFIEVHVDEIPEDELITILEQRCSIACSYATRMV 913
            +F+LFATQNPP +YGGRKILSRAFRNRF+E+H D+IP+DEL  IL +RC IA SYA ++V
Sbjct: 1187 DFLLFATQNPPGIYGGRKILSRAFRNRFLELHFDDIPQDELEIILRERCQIAPSYAKKIV 1246

Query: 914  QVMKDLQTHRQNSRVFAGKHGFITPRDLFRWANRYRLFEGKSYEDLAKDGYLLLAERLRD 973
            +V + L   R  SR+F  K+ F T RDLFRWA R    +   YE LA  GY+LLAER R 
Sbjct: 1247 EVYRQLSIERSASRLFEQKNSFATLRDLFRWALR----DAVGYEQLAASGYMLLAERCRT 1302

Query: 974  DTEKAVVQEVLERHLHVKLSISNLYNMEVSCDNNLSRESIRLRVQETFGNITWTESMWRL 1033
              EK  V++ LE+ + VKL +   Y             S+  +  E  G++TWT+ M RL
Sbjct: 1303 PQEKVTVKKTLEKVMKVKLDMDQYY------------ASLEDKSLEAIGSVTWTKGMRRL 1350

Query: 1034 YFLIERCYRSREPVLLVGETGGGKTTVCQVLSAVLGVKLHILNCHQYTETSDFIGGFCPI 1093
              L+  C +++EPVLLVGETG GKTT+CQ+L+  +G +L  LN HQ TET D +G   P+
Sbjct: 1351 SVLVSSCLKNKEPVLLVGETGCGKTTICQLLAQFMGRELITLNAHQNTETGDILGAQRPV 1410

Query: 1094 RDRSKIAMEFKHLITKMKQLKIFIHVAGDMSFPADISGAVSVVNHIDEILDRYIKEKELF 1153
            R+RS+I  +       +K LK  +++A D                + E+L  Y K     
Sbjct: 1411 RNRSEIQYKL------IKSLKTALNIANDQDV------------DLKELLQLYSKS---- 1448

Query: 1154 PQVPPHDFAAMEQIKLDLMQLHKRWQAIFLWQDGSLVQAMKNGDLFLIDEISLADDSVLE 1213
                  +    E ++L++ +L      +F W DG L+QAM+ G+ FL+DEISLADDSVLE
Sbjct: 1449 -----DNKNIAEDVQLEIQKLRDSLNVLFEWSDGPLIQAMRTGNFFLLDEISLADDSVLE 1503

Query: 1214 RLNSVLEPERKLSLAEKGGSVLEKVVAHPNFFILATMNPGGDYGKKELSPALRNRFTEVW 1273
            RLNSVLEPER L LAE+G S    V A  NF   ATMNPGGDYGKKELSPALRNRFTE+W
Sbjct: 1504 RLNSVLEPERSLLLAEQGSSD-SLVTASENFQFFATMNPGGDYGKKELSPALRNRFTEIW 1562

Query: 1274 VPAVTNVDELKSIAIERFTNAEVSCFGDCIVNFWMWFNQL-----HTGRMLTIRDLLSWI 1328
            VP++ + +++  I   R    ++    + IV F  WF +       T  ++++RD+L+W+
Sbjct: 1563 VPSMEDFNDVNMIVSSRLLE-DLKDLANPIVKFSEWFGKKLGGGNATSGVISLRDILAWV 1621

Query: 1329 SFIN-----VTERNLGPQQAXXXXXXXXXXXXXXXXMNVSKTEATELRRTCLSFLLE--- 1380
             FIN     +  ++    Q                 +  ++ +   LR  C+  LL+   
Sbjct: 1622 EFINKVFPKIQNKSTALIQGASMVFIDALGTNNTAYLAENENDLKSLRTECIIQLLKLCG 1681

Query: 1381 ---ELQKVEGKPLNSDLHDLKNYGWGDHTREIDIGQPDHFGIMPFYIDTGHFTRKQ-QGF 1436
               ELQ++E                   T EI + Q D   +  F I    F   Q   F
Sbjct: 1682 DDLELQQIE-------------------TNEIIVTQ-DELQVGMFKI--PRFPDAQSSSF 1719

Query: 1437 QFMAPTTSKNVFRVLRGMQLPKPLLLEGSPGVGKTSLIVALAGFSGHNVVRINLSEQTDM 1496
               APTT+ N+ RV+R MQ+ KP+LLEGSPGVGKTSLI ALA  +G+ + RINLSEQTD+
Sbjct: 1720 NLTAPTTASNLVRVVRAMQVHKPILLEGSPGVGKTSLITALANITGNKLTRINLSEQTDL 1779

Query: 1497 MDLLGSDLPVEGENGMEFAWSDGILLQALKNGSWVLLDELNLAPQSVLEGLNAILDHRAE 1556
            +DL G+D P  GE   EF W D   L+A+K G WVLLDE+NLA QSVLEGLNA LDHR E
Sbjct: 1780 VDLFGADAP--GERSGEFLWHDAPFLRAMKKGEWVLLDEMNLASQSVLEGLNACLDHRGE 1837

Query: 1557 VFIPELGQTYKCPPSFRVFACQNPSSQGGGRKGLPKSFLNRFTKVYVDELSESDYSFICK 1616
             +IPEL  ++ C P+F VFA QNP  QGGGRKGLPKSF+NRF+ V++D L+  D   I K
Sbjct: 1838 AYIPELDISFSCHPNFLVFAAQNPQYQGGGRKGLPKSFVNRFSVVFIDMLTSDDLLLIAK 1897

Query: 1617 SQYPSIKDDILKKLISFNNRLYMDTMIHKKYGQEGSPWEFNLRDIIRSCEMI--VGACET 1674
              YPSI+ DI+ K+I   + L       K +G  GSPWEFNLRD +R  +++     CE 
Sbjct: 1898 HLYPSIEPDIIAKMIKLMSTLEDQVCKRKLWGNSGSPWEFNLRDTLRWLKLLNQYSICED 1957

Query: 1675 ARGYPETSMVDCFLNTVYLQRMRTVADREEVVKLFEEVFQTKYSIHEIKMLYVNPQCLVV 1734
               +        F++ +  QR RT++D+ +   L E++F  K+S  E           + 
Sbjct: 1958 VDVFD-------FVDIIVKQRFRTISDKNKAQLLIEDIF-GKFSTKENFFKLTEDYVQIN 2009

Query: 1735 GSASIRRNRVHSCKVQNSQLNILPGTLHSLEAAMHCINQGWLCILVGQHSSGKTSLIRLL 1794
               ++R         QN  L  L   +   E+ +  IN  W  +LVG  +SGKT  IR L
Sbjct: 2010 NEVALRNPHYRYPITQN--LFPLECNVAVYESVLKAINNNWPLVLVGPSNSGKTETIRFL 2067

Query: 1795 AQLSGNTLNEVNLSSATDVSELLGCFEQYNFFRHYKVVISQVERYIDEYFSLS 1847
            A + G  ++  +++S  D  ++LG +EQ +  R    +  ++   + E  S++
Sbjct: 2068 ASILGPRVDVFSMNSDIDSMDILGGYEQVDLTRQISYITEELTNIVREIISMN 2120



 Score =  369 bits (947), Expect = e-100,   Method: Compositional matrix adjust.
 Identities = 368/1382 (26%), Positives = 624/1382 (45%), Gaps = 219/1382 (15%)

Query: 745  PVLLQGPTSSGKTSLVRFLAAQTG-HE-FVRINNHEHTDLQEYLGTYVT-DSHGKLQFQE 801
            P++L G   SGKT L+  L+   G H+  V+I+  E TD +  +GTY + D  G  +++ 
Sbjct: 310  PIMLIGKAGSGKTFLINELSKYMGCHDSIVKIHLGEQTDAKLLIGTYTSGDKPGTFEWRA 369

Query: 802  GALVKAVREGHWIVLDELNLAPSDVLEALNRLLDDNRELFVPELQETIPAHPNFMLFAT- 860
            G L  AV+EG W+++++++ AP+DVL  L  LL+  REL +P   ET+ A   F L +T 
Sbjct: 370  GVLATAVKEGRWVLIEDIDKAPTDVLSILLSLLE-KRELTIPSRGETVKAANGFQLISTV 428

Query: 861  --------QNPPVLYGGRKILSRAFRNRFIEVHVDEIPEDELITILEQRCSIACSYATRM 912
                     +   +Y    I  R +      + ++E  E++L  IL Q+  I  +   ++
Sbjct: 429  RINEDHQKDSSNKIYNLNMIGMRIWN----VIELEEPSEEDLTHILAQKFPILTNLIPKL 484

Query: 913  VQVMKDLQTHRQNSRVFAGKHG----FITPRDLFRWANRY-------------RLFEGKS 955
            +   K++++   N++  +   G     ++ RDL +   R              +L +   
Sbjct: 485  IDSYKNVKSIYMNTKFISLNKGAHTRVVSVRDLIKLCERLDILFKNNGINKPDQLIQSSV 544

Query: 956  YEDLAKDGYLLLAERLRD-DTEKAVVQEVLERHLHVKLSISNLYNMEVSCDNNLSRESIR 1014
            Y+ +  +     A  + +    + ++Q + E        IS      V    NL  +SI+
Sbjct: 545  YDSIFSEAADCFAGAIGEFKALEPIIQAIGESLDIASSRISLFLTQHVPTLENLD-DSIK 603

Query: 1015 ----------LRVQETFGNIT---WTESMWRLYFLIERCYRSREPVLLVGETGGGKTTVC 1061
                      L +Q+   N T   +T    RL   I  C +  EPVLLVGETG GKTTV 
Sbjct: 604  IGRAVLLKEKLNIQKKSMNSTLFAFTNHSLRLMEQISVCIQMTEPVLLVGETGTGKTTVV 663

Query: 1062 QVLSAVLGVKLHILNCHQYTETSDFIGGF---------CPIRDRSKIAMEFKHLITKMKQ 1112
            Q L+ +L  KL ++N  Q TET D +GG+          PI++  +        + K ++
Sbjct: 664  QQLAKMLAKKLTVINVSQQTETGDLLGGYKPVNSKTVAVPIQENFETLFNATFSLKKNEK 723

Query: 1113 LKIFIHVAGDMSFPADI-----------SGAVSVVNHIDEILDRYIKEKELFPQVPPHDF 1161
                +H   + +   ++              + + N  +E  +   K++ L      H+ 
Sbjct: 724  FHKMLHRCFNKNQWKNVVKLWNEAYKMAQSILKITNTENENENAKKKKRRL----NTHEK 779

Query: 1162 AAMEQIKLDLMQLHKRWQA---------IFLWQDGSLVQAMKNGDLFLIDEISLADDSVL 1212
              +     D     K+++A         +F + +GSLV+ ++ G+  L+DE++LA    L
Sbjct: 780  KLLLDKWADFNDSVKKFEAQSSSIENSFVFNFVEGSLVKTIRAGEWLLLDEVNLATADTL 839

Query: 1213 ERLNSVL-EPE-RKLSLAEKGGSVLEKVVAHPNFFILATMNPGGDYGKKELSPALRNRFT 1270
            E ++ +L EP+ R + L+EKG +  E + AHP+F I A MNP  D GK++L   +R+RFT
Sbjct: 840  ESISDLLTEPDSRSILLSEKGDA--EPIKAHPDFRIFACMNPATDVGKRDLPMGIRSRFT 897

Query: 1271 EVWVPAVT-NVDELKSIAIERFTNAEVS--CFGDCIVNFWMWFNQLHTGRMLTIRDLLSW 1327
            E++V +   ++ +L SI  +      VS    G+ I   ++   +L     +        
Sbjct: 898  EIYVHSPERDITDLLSIIDKYIGKYSVSDEWVGNDIAELYLEAKKLSDNNTI-------- 949

Query: 1328 ISFINVTERNLGPQQAXXXXXXXXXXXXXXXXMNVSKTEATELRRT-----CLSFLLEEL 1382
                 V   N  P  +                +         LRR+     C+SFL    
Sbjct: 950  -----VDGSNQKPHFSIRTLTRTLLYVTDIIHI-------YGLRRSLYDGFCMSFLTLLD 997

Query: 1383 QKVEG--KPL--NSDLHDLKNYGWGDHTREIDIGQPDHFGIMPFYIDTGHFTRKQQGFQF 1438
            QK E   KP+     L  LKN            G PD+     +++  G  T ++Q    
Sbjct: 998  QKSEAILKPVIEKFTLGRLKNVKSIMSQTPPSPG-PDYVQFKHYWMKKGPNTIQEQAHYI 1056

Query: 1439 MAPTTSKNVFRVLRGMQLPK-PLLLEGSPGVGKTSLIVALAGFSGHNVVRINLSEQTDMM 1497
            + P   KN+  ++R     + P+L++G    GKTS+I  LA  +GH  VRIN  E TD+ 
Sbjct: 1057 ITPFVEKNMMNLVRATSGKRFPVLIQGPTSSGKTSMIKYLADITGHKFVRINNHEHTDLQ 1116

Query: 1498 DLLGSDLPVEGENGMEFAWSDGILLQALKNGSWVLLDELNLAPQSVLEGLNAILDHRAEV 1557
            + LG+   V  + G + ++ +G+L++AL+ G W++LDELNLAP  VLE LN +LD   E+
Sbjct: 1117 EYLGT--YVTDDTG-KLSFKEGVLVEALRKGYWIVLDELNLAPTDVLEALNRLLDDNREL 1173

Query: 1558 FIPELGQTYKCPPSFRVFACQNPSSQGGGRKGLPKSFLNRFTKVYVDELSESDYSFICKS 1617
            FIPE  +     P F +FA QNP    GGRK L ++F NRF +++ D++ + +   I + 
Sbjct: 1174 FIPETQEVVHPHPDFLLFATQNPPGIYGGRKILSRAFRNRFLELHFDDIPQDELEIILRE 1233

Query: 1618 QYPSIKDDILKKLISFNNRLYMDTMIHKKYGQEGSPWEFNLRDIIRSCEMIVGACETARG 1677
            +   I     KK++    +L ++    + + Q+ S     LRD+ R       A   A G
Sbjct: 1234 RC-QIAPSYAKKIVEVYRQLSIERSASRLFEQKNSFA--TLRDLFR------WALRDAVG 1284

Query: 1678 YPETSMVDCFLNTVYLQRMRTVADREEVVKLFEEVFQTKYSIHEIKMLYVNPQCLVVGSA 1737
            Y + +     L     +R RT  ++  V K  E+V + K  + +      +     +GS 
Sbjct: 1285 YEQLAASGYML---LAERCRTPQEKVTVKKTLEKVMKVKLDMDQYYASLEDKSLEAIGSV 1341

Query: 1738 SIRRNRVHSCKVQNSQLNILPGTLHSLEAAMHCINQGWLCILVGQHSSGKTSLIRLLAQL 1797
            +  +           +L++L  +         C+      +LVG+   GKT++ +LLAQ 
Sbjct: 1342 TWTKGM--------RRLSVLVSS---------CLKNKEPVLLVGETGCGKTTICQLLAQF 1384

Query: 1798 SGNTLNEVNLSSATDVSELLGCFEQYNFFRHYKVVISQVERYIDEYFSLSQYIQWKSLVA 1857
             G  L  +N    T+  ++LG           + V ++ E            IQ+K L+ 
Sbjct: 1385 MGRELITLNAHQNTETGDILGA---------QRPVRNRSE------------IQYK-LIK 1422

Query: 1858 DRKTLFVKWFEFVIAKKFSSICISTLVEMSKNSSLPSLSLVRDIVEDMKCDMEMFDLPVS 1917
              KT               +I     V++ +   L S S  ++I ED++ +++       
Sbjct: 1423 SLKTAL-------------NIANDQDVDLKELLQLYSKSDNKNIAEDVQLEIQKL----- 1464

Query: 1918 FNKDDLSKTLRSIYYLQQSEAVHQPVKFEWVAGDLIRAIECGEWIVLDNANFCNPTVLDR 1977
              +D L+                  V FEW  G LI+A+  G + +LD  +  + +VL+R
Sbjct: 1465 --RDSLN------------------VLFEWSDGPLIQAMRTGNFFLLDEISLADDSVLER 1504

Query: 1978 INSLVEQERSIVVNECGLVDGNPVILKAHPKFRMFLTIN--AKHG--EVSRAMRNRGVEI 2033
            +NS++E ERS+++ E G  D    ++ A   F+ F T+N    +G  E+S A+RNR  EI
Sbjct: 1505 LNSVLEPERSLLLAEQGSSDS---LVTASENFQFFATMNPGGDYGKKELSPALRNRFTEI 1561

Query: 2034 FL 2035
            ++
Sbjct: 1562 WV 1563



 Score =  363 bits (931), Expect = 2e-98,   Method: Compositional matrix adjust.
 Identities = 367/1342 (27%), Positives = 613/1342 (45%), Gaps = 174/1342 (12%)

Query: 5    QKWPILLYGPVGAGKTALINKLAQIGGNRVLFIHMDEQMDGRTLIGSYVCTEKPGEFKWS 64
            +++P+L+ GP  +GKT++I  LA I G++ + I+  E  D +  +G+YV T+  G+  + 
Sbjct: 1075 KRFPVLIQGPTSSGKTSMIKYLADITGHKFVRINNHEHTDLQEYLGTYV-TDDTGKLSFK 1133

Query: 65   PGSLTQAVIKGFWIVFEDIDKAPSDVQSILLPLLEGSSSFSVGHA-EAVEVAENFRLFAT 123
             G L +A+ KG+WIV ++++ AP+DV   L  LL+ +    +    E V    +F LFAT
Sbjct: 1134 EGVLVEALRKGYWIVLDELNLAPTDVLEALNRLLDDNRELFIPETQEVVHPHPDFLLFAT 1193

Query: 124  VTTSKNDVSHALEGRLTFSALWRKVMVG---EPNRKDMIDII--HGCYPSLESISAKLID 178
                  +      GR   S  +R   +    +   +D ++II    C  +  S + K+++
Sbjct: 1194 -----QNPPGIYGGRKILSRAFRNRFLELHFDDIPQDELEIILRERCQIA-PSYAKKIVE 1247

Query: 179  TFEKANLLVSYQFGGLNLAGGSSECLVQRFS---LRDLLKWCKR--IRGVDLNFKGLGLS 233
             + +           L++   +S    Q+ S   LRDL +W  R  +    L   G  L 
Sbjct: 1248 VYRQ-----------LSIERSASRLFEQKNSFATLRDLFRWALRDAVGYEQLAASGYMLL 1296

Query: 234  SSCCKLIYFEAVDIFASSLSSLDKRLYVAREIAKLFCVPHGAETISPSDKPIIQARHTDL 293
            +  C+    E V +      +L+K + V  ++ + +         S  DK +        
Sbjct: 1297 AERCRTPQ-EKVTV----KKTLEKVMKVKLDMDQYYA--------SLEDKSL-------E 1336

Query: 294  QVGRVTLQCSDKPALIQKGPFADIRRALEVLERVACSIKFNEPVLLVGETGTGKTTLVQN 353
             +G VT           KG      R L VL  V+  +K  EPVLLVGETG GKTT+ Q 
Sbjct: 1337 AIGSVTWT---------KG-----MRRLSVL--VSSCLKNKEPVLLVGETGCGKTTICQL 1380

Query: 354  LASWLKQPLTVVNLSQQSDISDLLGGFKPADARSICFPLYIEFKDLFCRSFSGKDNEAIL 413
            LA ++ + L  +N  Q ++  D+LG  +P   RS      I++K    +S     N A  
Sbjct: 1381 LAQFMGRELITLNAHQNTETGDILGAQRPVRNRS-----EIQYK--LIKSLKTALNIAND 1433

Query: 414  RHCDVYVMEKKWKKLLRALEKCVEKAQKLIDXXXXXXXXXXXXXPLPAQVISDWDSFSSR 473
            +  D+       K+LL+   K                              SD  + +  
Sbjct: 1434 QDVDL-------KELLQLYSK------------------------------SDNKNIAED 1456

Query: 474  LNAACSQIGSEIGMSFQFVEGAFVSALRNGHWILLDEVNLAPPETLQRIGAVLDGESGTL 533
            +     ++   + + F++ +G  + A+R G++ LLDE++LA    L+R+ +VL+ E  +L
Sbjct: 1457 VQLEIQKLRDSLNVLFEWSDGPLIQAMRTGNFFLLDEISLADDSVLERLNSVLEPER-SL 1515

Query: 534  CLAERGDVD-YIERHPCFRMFACMNPATDAGKRELPYTFRSRFTEFFVXXXXXXXXXXXF 592
             LAE+G  D  +     F+ FA MNP  D GK+EL    R+RFTE +V            
Sbjct: 1516 LLAEQGSSDSLVTASENFQFFATMNPGGDYGKKELSPALRNRFTEIWVPSMEDFNDVNMI 1575

Query: 593  VSKYLDGLHAAKGVADSIVRFYKAAKKESEEKLQDGANQKPQFSLRSLSRSLGYIKNAER 652
            VS  L  L   K +A+ IV+F +   K    KL  G       SLR +   + +I     
Sbjct: 1576 VSSRL--LEDLKDLANPIVKFSEWFGK----KLGGGNATSGVISLRDILAWVEFINKVFP 1629

Query: 653  KFGFKK-ALYDGFCMFFLTMLDAPSAKII----NNL-------IVSLLL---DGRVPPRI 697
            K   K  AL  G  M F+  L   +   +    N+L       I+ LL    D     +I
Sbjct: 1630 KIQNKSTALIQGASMVFIDALGTNNTAYLAENENDLKSLRTECIIQLLKLCGDDLELQQI 1689

Query: 698  SFADYFVEKPKLLNG-----SESDDFLRSYVLTNSVT-EHIVNLACAVYIKKYPVLLQGP 751
               +  V + +L  G        D    S+ LT   T  ++V +  A+ + K P+LL+G 
Sbjct: 1690 ETNEIIVTQDELQVGMFKIPRFPDAQSSSFNLTAPTTASNLVRVVRAMQVHK-PILLEGS 1748

Query: 752  TSSGKTSLVRFLAAQTGHEFVRINNHEHTDLQEYLGTYVT-DSHGKLQFQEGALVKAVRE 810
               GKTSL+  LA  TG++  RIN  E TDL +  G     +  G+  + +   ++A+++
Sbjct: 1749 PGVGKTSLITALANITGNKLTRINLSEQTDLVDLFGADAPGERSGEFLWHDAPFLRAMKK 1808

Query: 811  GHWIVLDELNLAPSDVLEALNRLLDDNRELFVPELQETIPAHPNFMLFATQNPPVLYGGR 870
            G W++LDE+NLA   VLE LN  LD   E ++PEL  +   HPNF++FA QNP    GGR
Sbjct: 1809 GEWVLLDEMNLASQSVLEGLNACLDHRGEAYIPELDISFSCHPNFLVFAAQNPQYQGGGR 1868

Query: 871  KILSRAFRNRFIEVHVDEIPEDELITILEQ-RCSIACSYATRMVQVMKDLQTHRQNSRVF 929
            K L ++F NRF  V +D +  D+L+ I +    SI      +M+++M  L+      +++
Sbjct: 1869 KGLPKSFVNRFSVVFIDMLTSDDLLLIAKHLYPSIEPDIIAKMIKLMSTLEDQVCKRKLW 1928

Query: 930  --AGKHGFITPRDLFRWA---NRYRLFEGKSYEDLAKDGYLLLAERLRDDTEKAVVQEVL 984
              +G       RD  RW    N+Y + E     D      +++ +R R  ++K   Q ++
Sbjct: 1929 GNSGSPWEFNLRDTLRWLKLLNQYSICEDVDVFDFVD---IIVKQRFRTISDKNKAQLLI 1985

Query: 985  ERHLHVKLSISNLYNME---VSCDNNLSRESIRLRVQETFGNITWTESMWRLYFLIERCY 1041
            E       +  N + +    V  +N ++  +   R   T  N+   E    +Y  + +  
Sbjct: 1986 EDIFGKFSTKENFFKLTEDYVQINNEVALRNPHYRYPIT-QNLFPLECNVAVYESVLKAI 2044

Query: 1042 RSREPVLLVGETGGGKTTVCQVLSAVLGVKLHILNCHQYTETSDFIGGFCPI---RDRSK 1098
             +  P++LVG +  GKT   + L+++LG ++ + + +   ++ D +GG+  +   R  S 
Sbjct: 2045 NNNWPLVLVGPSNSGKTETIRFLASILGPRVDVFSMNSDIDSMDILGGYEQVDLTRQISY 2104

Query: 1099 IAMEFKHLITKM--KQLKIFIHVAGDMSFPADISGAVSVVNHIDEILDRYIKEKELFPQV 1156
            I  E  +++ ++    +K+  +    M     +   ++ +   ++  D   +    F  +
Sbjct: 2105 ITEELTNIVREIISMNMKLSPNATAIMEGLNLLKYLLNNIVTPEKFQDFRNRFNRFFSHL 2164

Query: 1157 PPHDFAAMEQIKLDLMQ--LHKRWQAIFLWQDGSLVQAMKNGDLFLIDEISLADDSVLER 1214
              H       + ++ M   + K     F W DG LV+A++ G   ++D  +L   SVL+R
Sbjct: 2165 EGHPLLKTMSMNIEKMTEIITKEASVKFEWFDGMLVKAVEKGHWLILDNANLCSPSVLDR 2224

Query: 1215 LNSVLEPERKLSLAEKGGSVLEKVV--AHPNFFILATMNPGGDYGKKELSPALRNRFTEV 1272
            LNS+LE +  L + E      +  V   HPNF +  TM+P   YG  ELS A+RNR  E+
Sbjct: 2225 LNSLLEIDGSLLINECSQEDGQPRVLKPHPNFRLFLTMDPK--YG--ELSRAMRNRGVEI 2280

Query: 1273 WVPAVTNVDEL--KSIAIERFT 1292
            +      +DEL  +S A +R T
Sbjct: 2281 Y------IDELHSRSTAFDRLT 2296



 Score =  267 bits (683), Expect = 1e-69,   Method: Compositional matrix adjust.
 Identities = 237/808 (29%), Positives = 390/808 (48%), Gaps = 131/808 (16%)

Query: 4324 DDDPNRSTEKY--ESGSSAKETQKNDRELRAKDEGALEEDPMETDCDEQGKNNNL--EDD 4379
            +DDPN   +K   +  S   + +  D+ L  K++   EED    + DEQ ++N    ++D
Sbjct: 4149 EDDPNAIDDKMWDDKASDNSKEKDTDQNLDGKNQ---EEDVQAAENDEQQRDNKEGGDED 4205

Query: 4380 PSTCEDVDQDTN---------DLMDKADAYDDRTAPEL----PE------PKD---DSE- 4416
            P+  ED D++           D+ ++ D   D    +L    PE      P+D   DSE 
Sbjct: 4206 PNAPEDGDEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEH 4265

Query: 4417 ---DVDMDGTEHIDEMDADGEELSPEEEKLAADGCLXXXXXXXXXXXXQHGDNEIDGEQE 4473
               D D+D ++ + + D + EE+  E+E++  +  +            + G  E  GE E
Sbjct: 4266 EESDEDVDMSDGMPD-DLNKEEVGNEDEEVKQESGIESDNEND-----EPGPEEDAGETE 4319

Query: 4474 HAEDGQMETNNMEKELHNIESLEHPSQGIQ----------PNNAEMDYNRE--SESNL-- 4519
             A D + E    + ++ N E  E    G +            +A M+ N+E   E N   
Sbjct: 4320 TALDEE-EGAEEDVDMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNTEG 4378

Query: 4520 -------ANSTDMNSAAAPSVNFSSNEVPSLEISMPNSGD--GSRLLSNSKPELQTDTPP 4570
                   A++ D++  AA   +  S    +         D  GS    N+  E Q D   
Sbjct: 4379 LDGVEEKADTEDIDQEAAVQQDSGSKGAGADATDTQEQDDVGGSGTTQNTYEEDQEDVTK 4438

Query: 4571 ----SQIKQTNPFRSIGDAMADWKERAKVSADTQDHQPEAEH-HIDDESATEFRYVPDSE 4625
                S+ + T   + +GD+M ++  R +   + Q +  E E+   ++E   EF +V  + 
Sbjct: 4439 NNEESREEATAALKQLGDSMKEYHRRRQDIKEAQTNGEEDENLEKNNERPDEFEHVEGAN 4498

Query: 4626 QST-SQALGNATADQ---INDDLQVKQSSMEDENRVQKEEHNTDRAPGDDHNLEVPHLQA 4681
              T +QALG+AT DQ   I++D+ +     E E  V ++E   D    DD  +++     
Sbjct: 4499 TETDTQALGSATQDQLQTIDEDMAIDDDREEQE--VDQKELVED---ADDEKMDI----- 4548

Query: 4682 SQSRTNKSENANNLEHREIQTDTYVQDSVQGETDETFGDFVSFKQPPAD-EKTVMRDDLA 4740
                          +  E+ +D    D+   + D     F+  ++   D E  +  +  +
Sbjct: 4549 --------------DEEEMLSDIDAHDA-NNDVDSKKSGFIGKRKSEEDFENELSNEHFS 4593

Query: 4741 NDRELSTPMEINITDVDMKGPIVD---------------WKSVELTTMKLSQELAEQLRL 4785
             D+E  + ++  I +++   P                  W   E++T  L   L EQLRL
Sbjct: 4594 ADQEDDSEIQSLIENIEDNPPDASASLTPERSLEESRELWHKSEISTADLVSRLGEQLRL 4653

Query: 4786 VMEPTLASKLQGDYRTGKRINMKKVIPYIASHFRRDKIWLRRTKPNKRNYQVVIAVDDSR 4845
            ++EPTLA+KL+GDY+TGKR+NMK++IPYIAS FR+DKIWLRRTKP+KR YQ++IA+DDS+
Sbjct: 4654 ILEPTLATKLKGDYKTGKRLNMKRIIPYIASQFRKDKIWLRRTKPSKRQYQIMIALDDSK 4713

Query: 4846 SMSEGKCGKVAIEALVTVCRAMSQLEVGQFAVASFGKKGNVKVLHDFDQVFNGEAGTNMI 4905
            SMSE KC K+A ++L  V + ++QLE G  ++  FG+  N+K +H FDQ F+ E+G    
Sbjct: 4714 SMSESKCVKLAFDSLCLVSKTLTQLEAGGLSIVKFGE--NIKEVHSFDQQFSNESGARAF 4771

Query: 4906 SSLSFEQDNKLEDEPVADLLMHLNTMLDTAVARSRTPSGQNPLQQLVLIISDGKFHEKEN 4965
                F Q+ K +   V  L+     + + A A        N   QL ++ISDG   + E 
Sbjct: 4772 QWFGF-QETKTD---VKKLVAESTKIFERARAMV-----HNDQWQLEIVISDGICEDHET 4822

Query: 4966 LKRCVRNVLNRKRMIAYVLLDG--HEESIMDSLEVS-----YQGTKLTMGKYMDSFPFPY 5018
            +++ VR     K M+ +V++DG    ESI+D  +V+     Y   +L + KY+D+FPF +
Sbjct: 4823 IQKLVRRARENKIMLVFVIIDGITSNESILDMSQVNYIPDQYGNPQLKITKYLDTFPFEF 4882

Query: 5019 YVMLKNIEALPRTLADLLRQWFELMQSA 5046
            YV++ +I  LP  L+ +LRQ+F  + S+
Sbjct: 4883 YVVVHDISELPEMLSLILRQYFTDLASS 4910



 Score =  147 bits (372), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 159/633 (25%), Positives = 280/633 (44%), Gaps = 83/633 (13%)

Query: 1452 RGMQLPKPLLLEGSPGVGKTSLIVALAGFSG--HNVVRINLSEQTDMMDLLGSDLPVEGE 1509
            R +Q   P++L G  G GKT LI  L+ + G   ++V+I+L EQTD   L+G+     G+
Sbjct: 303  RKIQNSTPIMLIGKAGSGKTFLINELSKYMGCHDSIVKIHLGEQTDAKLLIGT--YTSGD 360

Query: 1510 NGMEFAWSDGILLQALKNGSWVLLDELNLAPQSVLEGLNAILDHRAEVFIPELGQTYKCP 1569
                F W  G+L  A+K G WVL+++++ AP  VL  L ++L+ R E+ IP  G+T K  
Sbjct: 361  KPGTFEWRAGVLATAVKEGRWVLIEDIDKAPTDVLSILLSLLEKR-ELTIPSRGETVKAA 419

Query: 1570 PSFRVFACQ--NPSSQGGGRK---GLPKSFLNRFTKVYVDELSESDYSFICKSQYPSIKD 1624
              F++ +    N   Q         L    +  +  + ++E SE D + I   ++P + +
Sbjct: 420  NGFQLISTVRINEDHQKDSSNKIYNLNMIGMRIWNVIELEEPSEEDLTHILAQKFPILTN 479

Query: 1625 DILKKLISFNN--RLYMDT-MIHKKYGQEGSPWEFNLRDIIRSCEMI-VGACETARGYPE 1680
             I K + S+ N   +YM+T  I    G        ++RD+I+ CE + +         P+
Sbjct: 480  LIPKLIDSYKNVKSIYMNTKFISLNKGAHTRV--VSVRDLIKLCERLDILFKNNGINKPD 537

Query: 1681 TSMVDCFLNTVYLQRMRTVADREEVVKLFEEVFQ-------------TKYSIHEIKMLYV 1727
              +     ++++ +     A      K  E + Q             + +    +  L  
Sbjct: 538  QLIQSSVYDSIFSEAADCFAGAIGEFKALEPIIQAIGESLDIASSRISLFLTQHVPTLEN 597

Query: 1728 NPQCLVVGSASIRRNRVHSCKVQNSQLN--ILPGTLHSL---EAAMHCINQGWLCILVGQ 1782
                + +G A + + +++   +Q   +N  +   T HSL   E    CI      +LVG+
Sbjct: 598  LDDSIKIGRAVLLKEKLN---IQKKSMNSTLFAFTNHSLRLMEQISVCIQMTEPVLLVGE 654

Query: 1783 HSSGKTSLIRLLAQLSGNTLNEVNLSSATDVSELLGCFEQYNFFRHYKVVISQVERYIDE 1842
              +GKT++++ LA++    L  +N+S  T+  +LLG ++  N       +    E   + 
Sbjct: 655  TGTGKTTVVQQLAKMLAKKLTVINVSQQTETGDLLGGYKPVNSKTVAVPIQENFETLFNA 714

Query: 1843 YFSLSQ-------------YIQWKSLVADRKTLFVKWFE-FVIAKKFSSICISTLVEMSK 1888
             FSL +               QWK++V         W E + +A+  S + I+     ++
Sbjct: 715  TFSLKKNEKFHKMLHRCFNKNQWKNVVK-------LWNEAYKMAQ--SILKITNTENENE 765

Query: 1889 NSSLPSLSLVRDIVEDMKCDMEMFDLPVSFNKDDLSKTLRSIYYLQQSEAVHQPVKFEWV 1948
            N+      L      +      + D    FN D + K      +  QS ++     F +V
Sbjct: 766  NAKKKKRRL------NTHEKKLLLDKWADFN-DSVKK------FEAQSSSIENSFVFNFV 812

Query: 1949 AGDLIRAIECGEWIVLDNANFCNPTVLDRINSLVEQ--ERSIVVNECGLVDGNPVILKAH 2006
             G L++ I  GEW++LD  N      L+ I+ L+ +   RSI+++E G  D  P+  KAH
Sbjct: 813  EGSLVKTIRAGEWLLLDEVNLATADTLESISDLLTEPDSRSILLSEKG--DAEPI--KAH 868

Query: 2007 PKFRMFLTINAKHGEVSR----AMRNRGVEIFL 2035
            P FR+F  +N       R     +R+R  EI++
Sbjct: 869  PDFRIFACMNPATDVGKRDLPMGIRSRFTEIYV 901



 Score =  136 bits (343), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 56/93 (60%), Positives = 77/93 (82%)

Query: 1943 VKFEWVAGDLIRAIECGEWIVLDNANFCNPTVLDRINSLVEQERSIVVNECGLVDGNPVI 2002
            VKFEW  G L++A+E G W++LDNAN C+P+VLDR+NSL+E + S+++NEC   DG P +
Sbjct: 2190 VKFEWFDGMLVKAVEKGHWLILDNANLCSPSVLDRLNSLLEIDGSLLINECSQEDGQPRV 2249

Query: 2003 LKAHPKFRMFLTINAKHGEVSRAMRNRGVEIFL 2035
            LK HP FR+FLT++ K+GE+SRAMRNRGVEI++
Sbjct: 2250 LKPHPNFRLFLTMDPKYGELSRAMRNRGVEIYI 2282



 Score = 65.5 bits (158), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 36/114 (31%), Positives = 60/114 (52%), Gaps = 11/114 (9%)

Query: 1506 VEGENGMEFAWSDGILLQALKNGSWVLLDELNLAPQSVLEGLNAILDHRAEVFIPELGQT 1565
            +  E  ++F W DG+L++A++ G W++LD  NL   SVL+ LN++L+    + I E  Q 
Sbjct: 2184 ITKEASVKFEWFDGMLVKAVEKGHWLILDNANLCSPSVLDRLNSLLEIDGSLLINECSQE 2243

Query: 1566 YKCP------PSFRVFACQNPSSQGGGRKGLPKSFLNRFTKVYVDELSESDYSF 1613
               P      P+FR+F   +P         L ++  NR  ++Y+DEL     +F
Sbjct: 2244 DGQPRVLKPHPNFRLFLTMDPK-----YGELSRAMRNRGVEIYIDELHSRSTAF 2292



 Score = 62.8 bits (151), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 55/246 (22%), Positives = 98/246 (39%), Gaps = 13/246 (5%)

Query: 3388 VRYFLDEWPGHPGLLKILDIITSLLAIPLSTPXXXXXXXXXXXXXX-AQTLQENDSKFFL 3446
            V   L +WP H  L ++  +    L  P+ TP               A+  +   S+  L
Sbjct: 3305 VLKLLKQWPEHATLKELYRVSQEFLNYPIKTPLARQLQKIEQIYTYLAEWEKYASSEVSL 3364

Query: 3447 KDHLPQLFIIVSSWQRLELECWPILLQEVLEKYESNALKLWFPLRALLTQSC-----DXX 3501
             + +  +  ++ SW++LEL  W  L      K   +  K WF L   +  S         
Sbjct: 3365 NNTVKLITDLIVSWRKLELRTWKGLFNSEDAKTRKSIGKWWFYLYESIVISNFVSEKKET 3424

Query: 3502 XXXXXXXXXXXXXFVQTSSIGEFKRRLHLLLAFHGELSDGAGVGAYSSNSLKKIQNILYN 3561
                         F   S++GEF  RL L+ AF+  +     +G  SS    KI  +L+N
Sbjct: 3425 APNATLLVSSLNLFFSKSTLGEFNARLDLVKAFYKHIQ---LIGLRSS----KIAGLLHN 3477

Query: 3562 MFGYYMQFLPLVLXXXXXXXXXXXXDLKDQVKLYRWEQDPHSASIENFKRTRQKVFKLLQ 3621
               +Y QF PL+             ++ D + L  W+     A  ++ +++   ++K+++
Sbjct: 3478 TIKFYYQFKPLIDERITNGKKSLEKEIDDIILLASWKDVNVDALKQSSRKSHNNLYKIVR 3537

Query: 3622 CFNDIL 3627
             + D+L
Sbjct: 3538 KYRDLL 3543

Query: CNT0024955
Subject: sp|Q4L6B6|Y1500_STAHJ Uncharacterized protein SH1500
SV=1

 Score =  940 bits (2430), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 702/2198 (31%), Positives = 1108/2198 (50%), Gaps = 279/2198 (12%)

Query: 3    VNQKWPILLYGPVGAGKTALINKLA-QIGGNRVLFIHMDEQMDGRTLIGSYVCTEKPGEF 61
            V+    +LL GP  +G+TAL++ LA ++G    + +H+    D R LIGSYV T KPG+F
Sbjct: 21   VSSGQAVLLCGPSASGRTALLSHLASKLGAKPPIPLHLTTAQDTRDLIGSYVMTNKPGDF 80

Query: 62   KWSPGSLTQAVIKGFWIVFEDIDKAPSDVQSILLPLLEGSSSFSVGHAEAVEVAENFRLF 121
            ++  G L  A   G WI  E+I     D   +L  ++  + + SVG  + + V  +FR+ 
Sbjct: 81   RFILGPLAYAAQSGRWISIEEITTISQDSLLLLSSVV-NTRTLSVGSYQ-ISVHPDFRIH 138

Query: 122  ATVTTSKNDVSHALEGRLTFSALWRKVMVGEPNRKDMIDIIHGCYPSLESISAKLIDTFE 181
            A     K     AL   +  S  +  V+    N    +   H C   + +I A       
Sbjct: 139  A-----KTSADPALLSTIVKSMFYPLVLPPLGNHLFQVLTKH-CNRGICTILAH------ 186

Query: 182  KANLLVSYQFGGLNLAGGSSECLVQRFSLRDLLKWCKRIRGVDLNFKGLGLSSSCCKLIY 241
                 +  QF    L  G       R S  D++KW +RI   DL+ K  G  +   K + 
Sbjct: 187  -----IHVQFETHRLTAG-------RISASDMVKWARRI---DLDLKNGG--AVLNKAVQ 229

Query: 242  FEAVDIFASSLSS-LD--KRLYVAREIAKLFCVPHGAE--------------------TI 278
              +    A++L S LD   R+ + +   + F + +  E                     +
Sbjct: 230  EASAGTAATTLVSWLDDNTRMVMIKNAWEAFVLRYSKEQTRRAFLDILRLSLNIHEELML 289

Query: 279  SPSDKPIIQARHTDLQ----VGRVTLQCSDKPALIQKGPFADIRRALEVLERVACSIKFN 334
            S   K  +  RH   Q     GRV+L   + P                +LE ++ +I+ N
Sbjct: 290  STLLKIKVDIRHDYTQKRLVCGRVSLPFYESPDERSLDDICRTNHTTRLLEIISSAIRNN 349

Query: 335  EPVLLVGETGTGKTTLVQNLASWLKQPLTVVNLSQQSDISDLLGGFKPA----------D 384
            EP+LLVG TG GKTT +Q +A  L + L VVN+S Q+D +DLLGG+ PA          D
Sbjct: 350  EPLLLVGPTGIGKTTCLQVIARALGKKLHVVNMSSQTDAADLLGGYVPATLDRILRNLYD 409

Query: 385  ARSICFPLYIEFK--DLFC----RSFSGKDNEAILRHCDVYVMEKKWKKLLRALEKCVEK 438
            A +    LYI  +   +F     +S++ KD    L +C+   +    + L + + + VE+
Sbjct: 410  AITGSLGLYISVRKNQIFVTELHKSYAEKDIAKFLANCET-ALSGMRQVLRKEVGEVVEQ 468

Query: 439  A---QKLIDXXXXXXXXXXXXXPLPAQVISDWDSFSSRLNAA-CSQIGSE-IGMSFQFVE 493
                Q++                   Q + D    ++ L+   C ++ ++   M+F++ E
Sbjct: 469  GSTEQRVSHDKKYARRGTYENSLYFLQSLGDTLEQATELHKILCHEVETKKPTMAFKYQE 528

Query: 494  GAFVSALRNGHWILLDEVNLAPPETLQRIGAVLDGESGTLCLAERGDVDYIERHPCFRMF 553
            G  V AL  G WIL+DE+NLA  + L  I  +++ E   + + ++G   ++ ++P FR+F
Sbjct: 529  GLLVQALVKGDWILIDEINLASYDLLDVISQLVNPEHNEIAIPDKG---FVAKNPHFRVF 585

Query: 554  ACMNPATDAGKRELPYTFRSRFTEFFVXXXXXXXXXXXFVSKYL---DGL-HAAKGVADS 609
            A MNP +D GK++LP T R  FTE  V               YL   D +    +G+  +
Sbjct: 586  AAMNPGSDVGKKDLPPTIRRCFTEINVSEMSDDVDIVALTKSYLRMDDAMIEDRQGLDPN 645

Query: 610  IV-RFYKAAKKESEEKLQDGANQK-PQFSLRSLSRSLGYIKNAERKFGFKKALYDGFCMF 667
            +V + +   K  ++  L   A  K P FSLRSL R+L +        G ++++Y+GF + 
Sbjct: 646  VVYQLFTVLKARAKTDLVTAAEAKSPCFSLRSLCRALSFAHRFRAAAGLRRSMYEGFMLA 705

Query: 668  FLTMLDAPSAKIINNLIVSLLLDGR---------VPP----------RISFADYFV---- 704
            F +ML+  S + ++ LI+  LL+G          + P          + +  D  V    
Sbjct: 706  FGSMLNEKSRQAVHALILDKLLNGNKEYLLNPFIIQPFNKPCTAMIFQATTKDEAVTVEY 765

Query: 705  EKPKLLNGSESDDFLRS----YVLTNSVTEHIVNLACAVYIKKYPVLLQGPTSSGKTSLV 760
            ++P+  +G   ++  R+    YVLT S   ++  ++ A+   + P+LL+G TSSGKTSL+
Sbjct: 766  QEPQAAHGFLEEEKSRARSTDYVLTKSTRSYMTTISRAI-AAQLPILLEGTTSSGKTSLI 824

Query: 761  RFLAAQTGHEFVRINNHEHTDLQEYLGTYVTDS-HGKLQFQEGALVKAVREGHWIVLDEL 819
            + +A Q G    RINNHEHTDL EY G+Y  D   G+L F++G LV  +++GHW++LDEL
Sbjct: 825  KHIAKQFGCPITRINNHEHTDLSEYFGSYQPDPLTGQLVFKDGPLVTGMKQGHWVILDEL 884

Query: 820  NLAPSDVLEALNRLLDDNRELFVPELQETIPAHPNFMLFATQNPPVLYGGRKILSRAFRN 879
            N+A S++LEALNRLLDDNREL VP+ QE +   P F+LFATQNP   Y GRK+LS AF+N
Sbjct: 885  NMASSEILEALNRLLDDNRELLVPDTQEIVRPAPGFLLFATQNPSGSYAGRKMLSEAFQN 944

Query: 880  RFIEVHVDEIPEDELITILEQRCS---IACSYATRM---VQVMKDLQTHRQNSRVFAGKH 933
            RFI +   +I  +EL  IL  R +   +A  Y  ++   +Q +K   +HR N+ V    +
Sbjct: 945  RFIMIEFADISTEELKEILINRSTSRHLAPQYCEKLITTIQAIKMQLSHRNNNAVMT--N 1002

Query: 934  GFITPRDLFRWANRYRLFEGKSYEDLAKDGYLLLAERLRDDTEKAVVQEVLERHLHVK-L 992
              IT RDLFR A+R      ++  +LA   + L+ ER RD  +K +V E++ ++L +K  
Sbjct: 1003 ALITLRDLFRVADRL----PRTLTELAMGIFELIGERQRDPADKQLVAEIIAKNLGLKTF 1058

Query: 993  SISNL---YNMEVSCDNNLSRESIRLRVQE-------TFGNITWTESMWRLYFLIERCYR 1042
            S+S     Y + V    ++  ++++             F +I WT SM RL+ L+     
Sbjct: 1059 SVSAAEQEYAIRVRPIQSMIEKALKAGADSPKSAFLLKFQDIVWTPSMIRLFALLFTSVS 1118

Query: 1043 SREPVLLVGETGGGKTTVCQVLSAVLGVKLHILNCHQYTETSDFIGGFCPIRDRSKIAME 1102
            + E  LLVG +G GKTT  ++++A++  +L  +N H++TE++DFIG   P+R R  +   
Sbjct: 1119 NGESPLLVGVSGAGKTTSVELIAAIMAQQLVQVNLHKHTESADFIGSLRPLRSRESM--- 1175

Query: 1103 FKHLITKMKQLKIFIHVAGDMSFPADISGAVSVVNHIDEILDRYIKEKELFPQVPPHDFA 1162
              HL + +K+                   A +  N     +D+ +             +A
Sbjct: 1176 HAHL-SVLKEY------------------AATTTN-----VDKAV-------------YA 1198

Query: 1163 AMEQIKLDLMQLHKRWQAIFLWQDGSLVQAMKNGDLFLIDEISLADDSVLERLNSVLEPE 1222
             +++++  L         +F W+DG ++  MK G + L+DE+SLAD+SVLERLNSVLE  
Sbjct: 1199 EIKRLETTL------GTKLFEWEDGPILNCMKRGHILLLDEVSLADESVLERLNSVLETS 1252

Query: 1223 RKLSLAEKGGSVLEKVVAHPNFFILATMNPGGDYGKKELSPALRNRFTEVWVPAVTNVDE 1282
            R+L++AE   ++   V+AH  F ++ATMNP GDYGKKELSPA+R+R TE W+P + +++E
Sbjct: 1253 RELTVAE-NPNMPRPVIAHTGFKLIATMNPAGDYGKKELSPAMRSRLTEFWMPHIRDINE 1311

Query: 1283 LKSIAIERFTNAEVSCFG--------DCIVNFWMWFNQL-HTGRM-----LTIRDLLSWI 1328
            ++ I   +     +   G          + +F+   +++  +GR+     L+IRD+L+  
Sbjct: 1312 VRMILTRKLQKTAIYRLGHQQGLDVVSLLADFFAEMDRITQSGRLGDVFTLSIRDILAVC 1371

Query: 1329 SFINVTERNLGPQQAXXXXXXXXXXXXXXXXMNVSKTEATELRRTCLSFLLEELQKVEGK 1388
             +I   +   G +                  +   +T+   +   C     E +  +  +
Sbjct: 1372 DYITEVQTKEGTELGQMLIDAVTLSILDGLPV---RTQLGNM-PACREVKHEMVLYLANR 1427

Query: 1389 PLNSDLHDLK-----NYGWGDHTREIDIGQPDHFGIM------PFYIDTGHFTRKQQGFQ 1437
             L+++L D+             T E+   Q     ++      P Y +     RK   F+
Sbjct: 1428 ILSANLTDIDLIQDLTVSISKDTNELTFLQASTQTVLATIPPGPQY-NHAKALRKMTSFR 1486

Query: 1438 FMAPTTSKNVFRVLRGMQLPKPLLLEGSPGVGKTSLIVALAGFSGHNVVRINLSEQTDMM 1497
              APTT KN  R+ + ++  +P+LLEG PGVGK++L+ A+A   G+++VRINLSEQTD+ 
Sbjct: 1487 LDAPTTIKNACRIAKALRFQRPILLEGDPGVGKSALVSAIAEICGYSLVRINLSEQTDLS 1546

Query: 1498 DLLGSDLPVEGENGMEFAWSDGILLQALKNGSWVLLDELNLAPQSVLEGLNAILDHRAEV 1557
            DLLGSDLP   ENG  F W DG+LL+A+K G+++LLDELNLA Q+VLEGLN++LDHR  +
Sbjct: 1547 DLLGSDLP--AENG--FRWVDGVLLKAVKEGAFILLDELNLANQTVLEGLNSLLDHRRSL 1602

Query: 1558 FIPELGQTYKCPPSFRVFACQNPSSQGGGRKGLPKSFLNRFTKVYVDELSESDYSFICKS 1617
            FIPEL  + K P + R+F  QNP SQG GRKGLP+SF+NRF  VYVD L   DY +I  +
Sbjct: 1603 FIPELMLSVKSPDTLRIFGTQNPRSQGSGRKGLPQSFINRFLNVYVDVLKSQDYDWILSN 1662

Query: 1618 QYPSIKDDILKKLISFNNRLYMDTMIHKKYGQEGSPWEFNLRDIIRSCEMIVGACETARG 1677
             +  I   +L  ++    +L    +   K+G  G PWE N+RD++R C+M+      A+G
Sbjct: 1663 LFTDIPTYVLDYILGSTKQLRAG-LEELKFGISGGPWELNVRDMMRLCDMLTTTPGLAQG 1721

Query: 1678 YPETSMVDCFLNTVYLQRMRTVADREEVVKL------FEEVFQTKYSIH--EIKMLY-VN 1728
                +    + + ++  R RT  D   V  +       + V +   S H   ++ L+ V 
Sbjct: 1722 I-TLAHAKHYAHILFGYRFRTADDDAYVQNVLFSPHSLDSVAEATQSHHWYSLRPLWNVT 1780

Query: 1729 PQCLVVGSASIRRNRVHSCKVQNSQLN------ILPGTLHSLEAAMHCINQGWLCILVGQ 1782
               + +GS +I R       V  ++L+       L   L +LEA    + Q   CILVG 
Sbjct: 1781 EDVVKIGSLAIPRIDPVFRDVLGTKLSYAHTSCFLTAQLVALEALAVAVTQNLSCILVGS 1840

Query: 1783 HSSGKTSLIRLLAQLSGNTLNEVNLSSATDVSELLGCFEQYNFFRHYKVVISQVERYIDE 1842
              SGK+S++R LA +    L  ++ S+ATDVS+L+G +EQ +     K VI  +  ++  
Sbjct: 1841 PESGKSSILRTLADVVRQPLVHISASTATDVSDLIGAYEQVDVLYDLKSVIRDLCLFVHS 1900

Query: 1843 Y--------FSLSQYIQWKSLVADRKT---LFVKWFEFVIAKKFSSICISTLVEM----- 1886
                      S S++++  +   DR+    L  K     +    S +    L+E      
Sbjct: 1901 LPIKASYSAISFSEFLKDLTASLDREIGDGLGSKSRAISMESIVSEVVQKLLLEFMAKFS 1960

Query: 1887 ---------SKNSSL-PSLSLVRDIVE-DMKCDMEMFDLPVSFNKDDLSKTLRSIYYLQQ 1935
                     +KN SL  S  L +D    D +    M  +P      +L K++ S+Y   Q
Sbjct: 1961 PDLDSGGLAAKNFSLFCSEILTQDTTPVDERFSPHMPTIP------ELCKSMASLYLSTQ 2014

Query: 1936 SEAVHQPVKFEWVAGDLIRAIECGEWIVLDNANFCNPTVLDRINSLVEQERSIVVNECGL 1995
                 Q  +F W   +LIRA+E G W+ L NANFC P+VLDR+NSL+E+   + + E GL
Sbjct: 2015 QS---QTGRFVWRDSELIRALERGYWVELTNANFCMPSVLDRLNSLLERGGGLEILEQGL 2071

Query: 1996 VDGNPVILKAHPKFRMFLTINAKHGEVSRAMRNRGVEI 2033
             +   +  K HP FR+F++  A   ++SRA+RNR +E+
Sbjct: 2072 EETRSI--KVHPNFRLFISY-APTSDISRALRNRSLEL 2106



 Score =  232 bits (592), Expect = 5e-59,   Method: Compositional matrix adjust.
 Identities = 227/845 (26%), Positives = 397/845 (46%), Gaps = 110/845 (13%)

Query: 4232 KESASSKIDDISQLEGTANEMDALRKPDQAPKNDDDAVEMQDDFNAELSDVSEDPEGNDS 4291
            KE+A    +D   L G  N+ D  ++  Q    DD+A+EMQ+DF      +  D E  DS
Sbjct: 4058 KEAAKELCED--DLMGNQNDRD--QQEQQEKDGDDEAIEMQNDFGGMSESLHHDIEEEDS 4113

Query: 4292 GDEDDDTNLENQMGDTGDASEMVGKKSWDKDEDDDPNRSTEKYESGSSAKETQKNDRELR 4351
               D++  LE +MGD  +  E + ++++++D+D     S E+ ++ ++  +T     EL 
Sbjct: 4114 NGSDEEEVLEKEMGD--EQGEAIDERNYNEDDDSAEEYSDEQKKNTNNNNDTM----ELA 4167

Query: 4352 AKDEGALEEDPMETD-CDEQGKNNNLEDDPSTCED---VDQDTNDLMDKADAYDDRTAPE 4407
            A+++   ++D + ++  D  G+ +  + D +   D    + D NDL DK      ++   
Sbjct: 4168 AQEK---DQDSINSELSDPSGEQHEEQADATGSTDEQAQEDDYNDLDDKN--LSGQSDLS 4222

Query: 4408 LPEPKDDSEDVDMDGTEHIDEMDADGEELS-PEEEKLAADGCLXXXXXXXXXXXXQHGDN 4466
            +PE   + E V+ +  E   +M     +LS P+++  A +               +H ++
Sbjct: 4223 VPEADGEDETVNEELEEEQQQM----SDLSNPDQDACAIEEDDDRDLPSSDENAEEHDEH 4278

Query: 4467 E--IDGEQEHAEDGQMETNNMEKELHNIESLEHPSQGIQPNNAEMDYNRESESNLANSTD 4524
            E  +D +   A D Q   N+ +++    +++   +Q  Q  N E +  +++E +  N TD
Sbjct: 4279 EAPVDIDDNEASDEQSTYNDNDRD----DAINISAQQ-QATNDEEEMQKDTEYDQENITD 4333

Query: 4525 MNSAAAPSVNFSSNEVPSLEISMPNSGDGSRLLSNSKPELQTDTP---------PSQIKQ 4575
             N  A        NEV + +    +  +      N + + + ++           + +K+
Sbjct: 4334 SNPDA--------NEVGTNDQKQTHEDNDQFRQENIEDQWEAESTENSQGEGAESADLKE 4385

Query: 4576 TNPFRSIGDAMADWKERAKVSADTQDHQPEAEHHID----DESATEFRYVPDSEQSTSQA 4631
             NP  S+ +    WKER  +  D +  + EA    D         EF    DS+     A
Sbjct: 4386 GNPDMSLEEFQRIWKERLNIH-DRESEKDEAAEPQDMPLQSNKTVEF---DDSKSGRDGA 4441

Query: 4632 LGNATADQINDDLQVKQSSMEDENRVQKEEHNT---------DRAPGDDHNLEVP-HLQA 4681
            LG   +   N    +     ++ N  +  EHN+         DR P +  N E+    + 
Sbjct: 4442 LGLTESKHRN----LTNQEFDNPNEERNVEHNSSCETSQSSHDRPPAEHLNPEISDEGEE 4497

Query: 4682 SQSRTNKSENANNLEHREIQTDTYVQDSVQGETDETFGDFVSFKQPPADEKTVMRDDLAN 4741
            S + ++K E A     RE   D                       P  +    +   LA+
Sbjct: 4498 SSTASDKQEQAVLSHMRESSKD--------------------LLNPEGEVYQELAVSLAS 4537

Query: 4742 DRELSTPMEINITDVDMKGPIVDWKSVELTTMKLSQELAEQLRLVMEPTLASKLQGDYRT 4801
            +     P ++          ++D       T   +  LAE+LR+++EPT+ S L+GD+RT
Sbjct: 4538 EETKRAPEDVAAASARGNHLLLDLIK---QTSAAAFSLAERLRIILEPTVTSDLKGDFRT 4594

Query: 4802 GKRINMKKVIPYIASHFRRDKIWLRRTKPNKRNYQVVIAVDDSRSMSEGKCGKVAIEALV 4861
            GK++N++++IP+IAS F++DKIWLRRTKP+KR YQV++AVDDS SM+     K A++A+ 
Sbjct: 4595 GKKLNLRRIIPFIASEFQKDKIWLRRTKPSKRVYQVLLAVDDSSSMA--PIAKYALQAIT 4652

Query: 4862 TVCRAMSQLEVGQFAVASFGKKGNVKVLHDFDQVFNGEAGTNMISSLSFEQDNKLEDEPV 4921
             +  A   LEVGQ +V SFG+K   ++L      +N  +    I S +F Q+    +  V
Sbjct: 4653 LLFNACKFLEVGQLSVFSFGQK--FELLLPITDQYNDASLAYAIGSFTFAQN----ETRV 4706

Query: 4922 ADLLMHLNTMLDTAVARSRTPSGQNPLQQLVLIISDGKFHEKENLKRCVRNVLNRKRMIA 4981
            +D +   +  LD+     R   G +   QL+L+ISDG+  EK  + R +R  + R ++  
Sbjct: 4707 SDAISIASDYLDSV----RFFKGSDSALQLLLMISDGRLKEKGGVAREIRKCMGRGQLPV 4762

Query: 4982 YVLLDGHEESIMDSLEVSY----QGTKL-TMGKYMDSFPFPYYVMLKNIEALPRTLADLL 5036
             ++LD  ++SIMD   VS+     G ++     Y+D FPF  Y +L++IE LP TL  ++
Sbjct: 4763 LIVLDTDKKSIMDIKSVSFITDSSGKRVRQTSMYLDDFPFQCYALLRHIEDLPETLVAVI 4822

Query: 5037 RQWFE 5041
            ++W E
Sbjct: 4823 KRWIE 4827



 Score = 83.2 bits (204), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 108/408 (26%), Positives = 170/408 (41%), Gaps = 61/408 (14%)

Query: 2    AVNQKWPILLYGPVGAGKTALINKLAQIGGNRVLFIHMDEQMDGRTLIGSYVCTEKPGEF 61
            A+  + PILL G   +GKT+LI  +A+  G  +  I+  E  D     GSY      G+ 
Sbjct: 803  AIAAQLPILLEGTTSSGKTSLIKHIAKQFGCPITRINNHEHTDLSEYFGSYQPDPLTGQL 862

Query: 62   KWSPGSLTQAVIKGFWIVFEDIDKAPSDVQSILLPLLEGSSSFSVGHA-EAVEVAENFRL 120
             +  G L   + +G W++ ++++ A S++   L  LL+ +    V    E V  A  F L
Sbjct: 863  VFKDGPLVTGMKQGHWVILDELNMASSEILEALNRLLDDNRELLVPDTQEIVRPAPGFLL 922

Query: 121  FATVTTSKNDVSHALEGRLTFSALWRKVMVGEPNRKDMIDIIHGCYPSLESI-------- 172
            FAT      + S +  GR   S  ++       NR  MI+        L+ I        
Sbjct: 923  FAT-----QNPSGSYAGRKMLSEAFQ-------NRFIMIEFADISTEELKEILINRSTSR 970

Query: 173  ------SAKLIDTFEKANLLVSYQFGGLNLAGGSSECLVQRFSLRDLLKWCKRIRGVDLN 226
                    KLI T +   + +S++    N     +  L+   +LRDL +   R+    L 
Sbjct: 971  HLAPQYCEKLITTIQAIKMQLSHR----NNNAVMTNALI---TLRDLFRVADRLPRT-LT 1022

Query: 227  FKGLGLSSSCCKLIYFEAVDIFASSLSSLDKRLYVAREIAK-----LFCVPHGAETISPS 281
               +G+         FE +          DK+L VA  IAK      F V    +  +  
Sbjct: 1023 ELAMGI---------FELIG--ERQRDPADKQL-VAEIIAKNLGLKTFSVSAAEQEYAIR 1070

Query: 282  DKPIIQARHTDLQVGRVTLQCSDKPALIQKGPFADIRRALEVLERVA---CSIKFNEPVL 338
             +PI       L+ G      S K A + K  F DI     ++   A    S+   E  L
Sbjct: 1071 VRPIQSMIEKALKAG----ADSPKSAFLLK--FQDIVWTPSMIRLFALLFTSVSNGESPL 1124

Query: 339  LVGETGTGKTTLVQNLASWLKQPLTVVNLSQQSDISDLLGGFKPADAR 386
            LVG +G GKTT V+ +A+ + Q L  VNL + ++ +D +G  +P  +R
Sbjct: 1125 LVGVSGAGKTTSVELIAAIMAQQLVQVNLHKHTESADFIGSLRPLRSR 1172



 Score = 58.2 bits (139), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 43/131 (32%), Positives = 68/131 (51%), Gaps = 14/131 (10%)

Query: 785  YLGTYVTDSHGKLQFQEGALVKAVREGHWIVLDELNLAPSDVLEALNRLLDDNRELFVPE 844
            YL T  + + G+  +++  L++A+  G+W+ L   N     VL+ LN LL+    L + E
Sbjct: 2010 YLSTQQSQT-GRFVWRDSELIRALERGYWVELTNANFCMPSVLDRLNSLLERGGGLEILE 2068

Query: 845  --LQET--IPAHPNFMLFATQNPPVLYGGRKILSRAFRNRFIEVHVD-EIPEDELITILE 899
              L+ET  I  HPNF LF      + Y     +SRA RNR +E+ +D ++    L+ I+ 
Sbjct: 2069 QGLEETRSIKVHPNFRLF------ISYAPTSDISRALRNRSLELSIDIQVSHYNLLDIV- 2121

Query: 900  QRCSIACSYAT 910
             RC    S A+
Sbjct: 2122 -RCVYTSSTAS 2131

Query: CNT0024955
Subject: sp|Q2FH29|Y1302_STAA3 Uncharacterized protein SAUSA300_1302
OS=Staphylococcus haemolyticus (strain JCSC1435)
GN=SH1500 PE=3 SV=1

 Score = 95.5 bits (236), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 65/204 (31%), Positives = 109/204 (53%), Gaps = 7/204 (3%)

Query: 730 EHIVNLACAVYIKKYPVLLQGPTSSGKTSLVRFLAAQTGHEFVRINNHEHTDLQEYLG-- 787
           E + N A A++     +LL+GPT SGKT L   L+A       ++N     D +  LG  
Sbjct: 11  ESVFNDAKALFNLNKNILLKGPTGSGKTKLAETLSAAVNTPMHQVNCSVDLDAESLLGFK 70

Query: 788 TYVTDSHGKLQ--FQEGALVKAVREGHWIVLDELNLAPSDVLEALNRLLDDNRELFVPEL 845
           T  T+  G+ +  F +G ++KA+REGH + +DE+N+A  + L  LN +LD  R+L  P  
Sbjct: 71  TIKTNEQGQQEIVFIDGPVIKAMREGHILYIDEINMAKPETLPILNGVLDYRRQLTNPFT 130

Query: 846 QETIPAHPNFMLFATQNPPVLYGGRKILSRAFRNRFIEVHVDEIPEDELITILEQRCSIA 905
            E I A P F + A  N    Y G   ++ A +NRF+ + VD I  D L  +++Q+  + 
Sbjct: 131 GEVIKAAPGFNVIAAINEG--YVGTLPMNEALKNRFVVIQVDYIDGDILKDVIKQQSQLQ 188

Query: 906 -CSYATRMVQVMKDLQTHRQNSRV 928
             +   ++++  +DL+T  +  ++
Sbjct: 189 DDAIIEQIIKFNEDLRTMSKQGQI 212



 Score = 78.6 bits (192), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 60/199 (30%), Positives = 95/199 (47%), Gaps = 8/199 (4%)

Query: 1443 TSKNVFRVLRGM-QLPKPLLLEGSPGVGKTSLIVALAGFSGHNVVRINLSEQTDMMDLLG 1501
            + ++VF   + +  L K +LL+G  G GKT L   L+      + ++N S   D   LLG
Sbjct: 9    SDESVFNDAKALFNLNKNILLKGPTGSGKTKLAETLSAAVNTPMHQVNCSVDLDAESLLG 68

Query: 1502 SDLPVEGENGM-EFAWSDGILLQALKNGSWVLLDELNLAPQSVLEGLNAILDHRAEVFIP 1560
                   E G  E  + DG +++A++ G  + +DE+N+A    L  LN +LD+R ++  P
Sbjct: 69   FKTIKTNEQGQQEIVFIDGPVIKAMREGHILYIDEINMAKPETLPILNGVLDYRRQLTNP 128

Query: 1561 ELGQTYKCPPSFRVFACQNPSSQGGGRKGLP--KSFLNRFTKVYVDELSESDYSFICKSQ 1618
              G+  K  P F V A  N    G     LP  ++  NRF  + VD +       + K Q
Sbjct: 129  FTGEVIKAAPGFNVIAAINEGYVG----TLPMNEALKNRFVVIQVDYIDGDILKDVIKQQ 184

Query: 1619 YPSIKDDILKKLISFNNRL 1637
                 D I++++I FN  L
Sbjct: 185  SQLQDDAIIEQIIKFNEDL 203



 Score = 53.5 bits (127), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 35/115 (30%), Positives = 61/115 (53%), Gaps = 5/115 (4%)

Query: 1160 DFAAMEQIKLDLMQLHKRWQAIFLWQDGSLVQAMKNGDLFLIDEISLADDSVLERLNSVL 1219
            D  A   +    ++ +++ Q   ++ DG +++AM+ G +  IDEI++A    L  LN VL
Sbjct: 60   DLDAESLLGFKTIKTNEQGQQEIVFIDGPVIKAMREGHILYIDEINMAKPETLPILNGVL 119

Query: 1220 EPERKLSLAEKGGSVLEKVVAHPNFFILATMNPGGDYGKKELSPALRNRFTEVWV 1274
            +  R+L+    G    E + A P F ++A +N G   G   ++ AL+NRF  + V
Sbjct: 120  DYRRQLTNPFTG----EVIKAAPGFNVIAAINEGY-VGTLPMNEALKNRFVVIQV 169