Score =  612 bits (1578), Expect = e-175,   Method: Compositional matrix adjust.
 Identities = 421/1207 (34%), Positives = 607/1207 (50%), Gaps = 159/1207 (13%)

Query: 2277 LQLLVAHRRIIFCPSNIDTDLNCCLCVNLISL---------------------------- 2308
            L++L  +R +I  P N D +   CL   LI+L                            
Sbjct: 2120 LRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAGSVEGFGLEAEARMTTWHIMIPSDIE 2179

Query: 2309 --------LCDKRQNVQNITIDVFKYLLVHRRAALEDLL-VSRPNQGQQLDVLHGGFDKL 2359
                    + + RQ +      V+  L+  ++  LE+L  VS P   +      G  D  
Sbjct: 2180 PDGGYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVSLPVNDR------GHVDIA 2233

Query: 2360 LTRSLSE--FFEWYQNIEQVVNKVLEQCAGIMWVQYIAGSAKFPGVRIKGMEG--RRKKE 2415
            L R L E    + +QN      K + +   ++       S    G  +  + G  R +KE
Sbjct: 2234 LARPLIEEAGLKCWQNHLAHEKKCISRGEALVPTTQSKLSRVSSGFGLSKLTGSRRNRKE 2293

Query: 2416 MGRKSREAAKLDLRHWEQVNERRYALDLVRDTMSTELRVVRQDKYGWILHAESEWQCHLQ 2475
             G      +  ++  W   +     + +VRD + T+ +  ++ +   + +   EW C ++
Sbjct: 2294 SGLHKHSPSPQEISQWMFTH-----IAVVRDLVDTQYKEYQERQQNALKYVTEEW-CQIE 2347

Query: 2476 -QLVHERGIF--PLSKSSFSEEPEWQLCPIEGPYRMRKKLECCKLKIDTIQNILDGQFEL 2532
             +L+ ERG++  P+     S   +W L   EGP RMRKK+    ++ D   N      E 
Sbjct: 2348 CELLRERGLWGPPIG----SHLDKWMLEMTEGPCRMRKKM----VRNDMFYNHYPYVPET 2399

Query: 2533 EKPELSKGKFEN--GPDSSESKPYFQLLTDGGKQNGSDGEPFDEPFFDKLDSVKDAVSAK 2590
            E+ E S GK        S +SK Y+  L  G                     V+DA+   
Sbjct: 2400 EQ-EASVGKPARYRRAISYDSKEYYLRLASGNPA-----------------IVQDAIVES 2441

Query: 2591 NEWNDDKASSINEASLHSALELGAKSSAVSVPIEESTQGRSDMGSPRQSSMKIDDVKIAD 2650
            +E       +  +   H    +      V  P++ S +   D G         D +  + 
Sbjct: 2442 SE-----GEATQQEPEHGEDTIAKVKGLVKPPLKRS-RSAPDGGDEETQEQLQDQIAESG 2495

Query: 2651 DKSDKELHDNGEYLIRPFLEPFEKIRFKYNCERVISLDKHDGIFLIGEFSLYVIENFYID 2710
               ++E  DN   L+R  LE  EKI+  Y C RV  LD  +G+ L G+      E+FY  
Sbjct: 2496 SIEEEEKTDNAT-LLR-LLEEGEKIQHMYRCARVQGLDTSEGLLLFGK------EHFY-- 2545

Query: 2711 DSGCFCEKECEDELSVIDQALGVKKDVSGSVDFQSKSTLSWSTPAKSLVGGRAWAYSGGA 2770
                           VID        ++ + + +   TL  +     +  G   A  G +
Sbjct: 2546 ---------------VIDGF-----TMTATREIRDIETLPPNMHEPIIPRG---ARQGPS 2582

Query: 2771 WGKEKVHSSGNLPHPWRMWKLDSVHEILKRDYQLRPVAIEIFSMDGCNDLLVFHKKEREE 2830
                       L     ++  + + E+ KR Y L+P+A+E+FS DG N LL F K  R +
Sbjct: 2583 ----------QLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNK 2632

Query: 2831 VFKNLVAINLPRNSMLDTTISGSSKQESNE-GSRLFKIMA--KSFSKRWQNGEISNFQYL 2887
            V++  +A+ +P  +    ++SG     S E GS L   +   KS ++RW+ GEISNFQYL
Sbjct: 2633 VYQRFLAV-VPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYL 2691

Query: 2888 MHLNTLAGRGYSDLTQYPVFPWVLADYESENLDLSNPKTFRRLDKPMGCQTPEGEDEFRK 2947
            MHLNTLAGR Y+DL QYPVFPW+L+DY+SE +DL+NPKTFR L KPMG QT E   +++K
Sbjct: 2692 MHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKK 2751

Query: 2948 RYESWDDP--EVPKFHYGSHYSSAGIVLFYLLRLPPFSTENQKLQGGQFDHADRLFNSIR 3005
            RY+ W+DP  E P +HYG+HYSSA IV  YL+R+ PF+    +LQGG FD ADR+F+S+R
Sbjct: 2752 RYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVR 2811

Query: 3006 DTWLSAAGKGNTSDVKELIPEFFYMPEFLENRFNLDLGEKQSGEKVGDVVLPLWAKGSAR 3065
            + W SA+ K N +DVKELIPEFFY+PEFL N  N DLG KQ+G K+GDV+LP WAKG  R
Sbjct: 2812 EAWYSAS-KHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPR 2870

Query: 3066 EFISKHREALESNYVSENLHHWIDLIFGYKQRGKAAEESVNVFYHYTYEGSVDIDSVTDP 3125
            EFI  HREALE +YVS +LH WIDLIFGYKQ+G AA E+VNVF+H  YEG VDI ++ DP
Sbjct: 2871 EFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDP 2930

Query: 3126 AMKASILAQINHFGQTPKQLFLKPHVKRRTDRKL---------PPHP------LKHSSHL 3170
              + + +  IN+FGQ PKQLF KPH  +R   +L         PP          H  +L
Sbjct: 2931 LKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGISVPPGATSDKIFFHHLDNL 2990

Query: 3171 --AAHEIRKSSSPITQIVTLNDKILIAGTNNLLKPRTYTKYVAWGFPDRSLRFISYEQDK 3228
              +   +++   P+ QIV  +  IL    N +L P  + K  AWG+ D S R  +YE DK
Sbjct: 2991 RPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDK 3050

Query: 3229 LLSTHENLHGGNQIQCASVSHDGHILVTGADDGLVNVWRVSKFGPRALRRLKLEKPLCGH 3288
             ++ +E L    QI CA V  +  +++TG    +V VW +     +A + L L++ L GH
Sbjct: 3051 AVTVYECLSEWGQILCA-VCPNPKLVITGGTSTVVCVWEMGTSKEKA-KPLTLKQALLGH 3108

Query: 3289 TAKITCLQVSQPYMLIVSGSDDCTVIIWDLSSMAFVRQLPEFPASVSAIYVNDLTGEIVT 3348
            T  +TC   S  Y +IVSGS D T IIWDL+ ++F+ QL    A VSA+ +N+LTG+IV+
Sbjct: 3109 TDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVS 3168

Query: 3349 AAGILLAVWSINGDCLALIKASQLPSDSILSVTSSTFSDWLDTKWYATGHQSGAVKVWQM 3408
             AG  + VWSING+ +  +      S  I+    S  ++W       TGH  G V+ W+M
Sbjct: 3169 CAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRM 3228

Query: 3409 VHCSNPD 3415
                 P+
Sbjct: 3229 EFLQVPE 3235



 Score =  100 bits (250), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 103/423 (24%), Positives = 172/423 (40%), Gaps = 49/423 (11%)

Query: 972  GERSWPPAAGYSFVCWFQFRNFLKSQSKDTDVSKFASSKKRSGSSGLHERHILRIFS--- 1028
            GER +PP +G S+ CWF   +F  S   +    +  +  +R+ SS  H   +  + S   
Sbjct: 1090 GERFFPPPSGLSYSCWFCIEHF--SSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKD 1147

Query: 1029 ----VGATNNDNATYAELYLQEDGVLTLATSNXXXXXXXXXXXXXXRWHHLAVIHSKPNA 1084
                V         Y + + +E     +                  +WHHLA++ S+   
Sbjct: 1148 RSLIVSTKEELLQNYVDDFSEESSFYEILPC--CARFRCGELVVEGQWHHLALLMSR--- 1202

Query: 1085 LAGLFQASFAYVYLNGKLRHTGKLGYSPCPPG----------KQLQVTIGTSVGNARVSD 1134
              G+ + S A +YL+G+L  T KL Y    PG            +   +GT     +++ 
Sbjct: 1203 --GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIAS 1260

Query: 1135 LTWKLRSCYLFEEVLSPGCICFMYILGRGYRGLFQDTDLLQFVP-NQACGGGSMAILDSL 1193
            L W+L   +  EEVL P  +  +Y LG  Y G FQ       VP   A   G      SL
Sbjct: 1261 LVWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAV----CVPCKDAKSEGVTPSPVSL 1316

Query: 1194 DADVTLAANGQRLDAASKQGDLKADGSGIVWDLERLGNLSLQLSGKKLIFAFDGTSTEFI 1253
             A+  ++     L  +S               + R+  +  +L  K +      +S E  
Sbjct: 1317 VAEEKVSFGLYALSVSS-------------LTVARIRKVYNKLDSKAIAKQLGISSHE-- 1361

Query: 1254 RSSGSFSMLNLVDPMSAAASPIGGIPRLGRLCGDIYICKQGVIGETIRPIGGMELVLALV 1313
             ++    + N    ++  A  IG    +G L    ++ K   +  T++ IGG   +L LV
Sbjct: 1362 NATPVKLVHNAAGHLNGPARTIGAA-LIGYLGVRTFVPKP--VATTLQYIGGAAAILGLV 1418

Query: 1314 EAAETRDMLHMALTLLACALHQNPQNLKDMQIYRGYHLLALFLRRRMSLFDMQSLEIFFQ 1373
              A   + L+ A+  L C +  NP   K+M+  +GY LLA+ L+++ SL +   L + F 
Sbjct: 1419 AMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFS 1478

Query: 1374 IAA 1376
            +  
Sbjct: 1479 LVG 1481



 Score = 72.0 bits (175), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 140/708 (19%), Positives = 261/708 (36%), Gaps = 139/708 (19%)

Query: 8   FSFVVGRAFVTDIEKLKISSKTRSLDVAPVLKFFSEVTKDGISPGANLLTSVEILVS-GP 66
           F+  V R  VT+I + + S+K+       +++F      +  S G  LLT++ +L S G 
Sbjct: 80  FTTQVSRLMVTEIRR-RASNKSTEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQ 138

Query: 67  IDKQSLLDSGIFCCLIQVLNALLD-PDVTIQRPNSTTDHEDNLVLQKVYDEVGPNRRLEV 125
                +    +   L++ L    D P V    P +    ++ L L +        RR  +
Sbjct: 139 KTVDCMTTMSVPSTLVKCLYLFFDLPHV----PEAGGGAQNELPLAE--------RRGLL 186

Query: 126 EGSVVHIMKALASHPSAAQSLIEDDSLQLLFQMVAKGSLIVFSRYKEGLVPLHSIQLHRH 185
           + + V I+  L S  S A+ L + D LQLLF  +                P +++   + 
Sbjct: 187 QKAFVQILVKLCSFVSPAEELAQKDDLQLLFSAIT------------SWCPPYNLPWRKS 234

Query: 186 AMQILGLLLVNDNGSTAKYIRKHHLIKVLLLSVKDFDPDCGDAAFTVGIVDLLLKCVELS 245
           A ++L  + ++ +G +   ++  H  + L   V++      D    + IV++        
Sbjct: 235 AGEVL--MTISRHGLSVNVVKYIHEKECLSTCVQNMQQ--SDDLSPLEIVEMFAGLSCFL 290

Query: 246 YRAEAASVRLREDIHNAHGYQFLVQFALTLSNMTKNQGFQSTHYDTFDEQEIASDGSKNS 305
             +   S  L +D     GY FL    L L      QG ++   D               
Sbjct: 291 KDSSDVSQTLLDDFRIWQGYNFLCDLLLRL-----EQGKEAECRDA-------------- 331

Query: 306 RGQNSNEQEHSSIQYLSPTLSRLLDVLVSLAQTGPNE-------SPRNYGGKGSKSTQNK 358
                              L  L+ ++ SL   G +E       +   +   G    Q  
Sbjct: 332 -------------------LKDLVSLVTSLTTYGVSELKPAGVTTGAPFLLPGFAVPQPA 372

Query: 359 GGGHSKSRTSSSDWLGDELWEKENDKIKDLEAVQMLQDILIKADSWKLQAEVLNRLFKIF 418
           G GHS                     +++++A  +LQ+  +KA +  L   +L+ +  I+
Sbjct: 373 GKGHS---------------------VRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIY 411

Query: 419 SGHIENYSLCQQLRTVPLLILNMAGFPSHLQEIILKILEYAVTVVNCVPXXXXXXXXXXX 478
                NY + +   T+      ++  P  +Q    ++LE+ V  +N +P           
Sbjct: 412 MADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILL 470

Query: 479 XXPITSALKQTILSFFVKLLSFDQQYKKVLREVGVLEVMLDDLKQHRILGPD-QQTVNSD 537
               +       +   +K    D  +K V REVG+LEVM++ L ++  L  D  Q +N  
Sbjct: 471 KSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPAQALNEQ 530

Query: 538 QLERKNSSNNFKKHLDNKDVIITSPKLMESGSGKFPIFDVEATIAIAWDCMVSLLKKAEV 597
              R NSS   +KHL                              +  + +  LL+ +  
Sbjct: 531 GDSRNNSSVEDQKHL----------------------------ALLVMEALTVLLQGSNT 562

Query: 598 NQASFRSASGVTVMLPFLVSDVHRSGVLRILSCLIIEDTSQAHPEELGVLVEILKSGMVT 657
           N   FR   G       +     R   L  +  L++    +   +++G L+     G++ 
Sbjct: 563 NAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGE---DDMGTLL-----GLMH 614

Query: 658 SASGSQYRLTLDAKCDTMGAMWRILGVNNSAQKVFGEATGFSLLLTTL 705
           SA  ++ +L    K D + A+  +L  ++ ++ VF +  GF  + + L
Sbjct: 615 SAPPTELQL----KTDILRALLSVLRESHRSRTVFRKVGGFVYITSLL 658

 Score =  594 bits (1531), Expect = e-169,   Method: Compositional matrix adjust.
 Identities = 320/758 (42%), Positives = 443/758 (58%), Gaps = 91/758 (12%)

Query: 2679 YNCERVISLDKHDGIFLIGEFSLYVIENFYIDDSGCFCEKECEDELSVIDQALGVKKDVS 2738
            YNC  V  +DK +GI +     +Y+ + +Y D        E   ++S +++ +  +    
Sbjct: 2816 YNCGSVDGMDKIEGILIFCPVYMYIFDGYYKD--------ENTGDISEVEEKINSE---- 2863

Query: 2739 GSVDFQSKSTLSWSTPAKSLVGGRAWAYSGGAWGKEKVHSSGNLPHPWRMWKLDSVHEIL 2798
                                     W   G     +K      + H +  W  + + ++L
Sbjct: 2864 -------------------------WLPEGTVLPMKK-----KIIHYFLKWAYEDIRDVL 2893

Query: 2799 KRDYQLRPVAIEIFSMDGCNDLLVFHKK-EREEVFKNLVAINLPRNSMLDTTISGSSK-- 2855
            KR Y LR VA+EIFS DG N+L+V+  +  R+EV+  LV      N     TI G ++  
Sbjct: 2894 KRRYLLRQVALEIFSTDGRNNLVVYRDEPTRDEVYHTLV-----NNVSSHNTIGGDAQGI 2948

Query: 2856 -----------------QESNEGSRLFKIMAKS-FSKRWQNGEISNFQYLMHLNTLAGRG 2897
                                    R   I  KS  + +WQ G+ISNFQYLMHLNTLAGR 
Sbjct: 2949 TGGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLKWQQGQISNFQYLMHLNTLAGRS 3008

Query: 2898 YSDLTQYPVFPWVLADYESENLDLSNPKTFRRLDKPMGCQTPEGEDEFRKRYESWDDPE- 2956
            Y+DLTQYPVFPWVL+DYESE LD+ +PK +R L KPMG        +FR+R+E+WDD E 
Sbjct: 3009 YNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPMGALEESRAQKFRERFENWDDQEP 3068

Query: 2957 ------VPKFHYGSHYSSAGIVLFYLLRLPPFSTENQKLQGGQFDHADRLFNSIRDTWLS 3010
                  VPKFHYG+HYSSA IVL+YL+RL PF+    KLQGG++D  DRLF+SI + W S
Sbjct: 3069 NEHGHKVPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQPDRLFSSITEAWAS 3128

Query: 3011 AAGKGNTSDVKELIPEFFYMPEFLENRFNLDLGEKQSGEKVGDVVLPLWAKGSAREFISK 3070
            ++ +G+T  V ELIPEF+Y+ EFL N    + G KQ GE + D++LP WAKGS +EFI  
Sbjct: 3129 SS-QGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIILPPWAKGSPQEFIKL 3187

Query: 3071 HREALESNYVSENLHHWIDLIFGYKQRGKAAEESVNVFYHYTYEGSVDIDSVTDPAMKAS 3130
            HR+ALES+YVSE+LH WIDLIFGY+Q+GKAA++S+NVFY+ TYEG+V+ID+++DP  KA+
Sbjct: 3188 HRKALESDYVSEHLHEWIDLIFGYRQQGKAADDSLNVFYYLTYEGAVNIDAISDPVEKAA 3247

Query: 3131 ILAQINHFGQTPKQLFLKPHVKRRTDRKLPPHPLKHSSHLAAHEIRKSSSPITQIVTLND 3190
             +AQIN+FGQTPKQLF KPH KR       P    ++  L  + I+    P+ QI  +ND
Sbjct: 3248 TIAQINNFGQTPKQLFDKPHPKRNATLMGLPF---YAKALTGNFIKDIGEPVGQIRLIND 3304

Query: 3191 KILIAGTNNLLKPRTYTKYVAWGFPDRSLRFISYEQDKLLSTHENLHGGNQIQCASVSHD 3250
            +    G N +L P  ++KY+ WG PD S+R+ + ++ K+L  H   H G  + C + + D
Sbjct: 3305 RATCVGFNKVLLPPNHSKYMLWGLPDGSIRYNTGDKIKVLEDH---HDG-PLTCLTATED 3360

Query: 3251 GHILVTGADDGLVNVWRVSKFGPRALRRLKLEKPLCGHTAKITCLQVSQPYMLIVSGSDD 3310
            G I V+G  D L+ V+         L+R  L K L GHT  ITC+  S+PY +IVSGSDD
Sbjct: 3361 GRICVSGGSDSLICVYN--------LKRFSLAKRLSGHTGSITCVSASRPYSIIVSGSDD 3412

Query: 3311 CTVIIWDLSSMAFVRQLPEFPASVSAIYVNDLTGEIVTAAGILLAVWSINGDCLALIKAS 3370
             T IIWDL+ + +VR L      +S I ++D TGEIV  +G  ++V+++NG+ L   K S
Sbjct: 3413 RTCIIWDLNRLCYVRSLDAHEGPISCIGIHDTTGEIVVCSGTTISVYTVNGELLINYKTS 3472

Query: 3371 QLPSDSILSVTSSTFSDWLDTKWYATGHQSGAVKVWQM 3408
            Q+ +D I     S   +WL      TGH+ G VKVW +
Sbjct: 3473 QIANDQITCCIWSKGPEWLGENVLLTGHRDGKVKVWGL 3510



 Score =  147 bits (370), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 188/878 (21%), Positives = 352/878 (40%), Gaps = 153/878 (17%)

Query: 574  IFDVEATIAIAWDCMVSLLKKAEVNQASFRSASGVTVMLPFLVSDVHRSGVLRILSCLII 633
            I  VE+   I  D +  L+ +   N +  RS S   ++L FL     R   LRIL  LI 
Sbjct: 719  IIKVES-FQILLDSLFILISENPDNISLIRSFSIFNILLRFLPYSSVRGKSLRILQQLIK 777

Query: 634  EDTSQAHPEELGVLVEILKSGMVTSASGSQYRLTLDAKCDTMGAMWRILGVNNSAQKVFG 693
             D      E  G L+++L     TS +   Y +    K D + A  ++  ++  A+  F 
Sbjct: 778  YDPEPTQKEFDG-LIKVL-----TSVNKENYPM----KSDILNATRKLFNISKHARDSFR 827

Query: 694  EATGFSLLLTTLHGFXXXXXXXXXXXXN---AYIKVFTYLLRVVTAGVSDNAVNRMKLHA 750
            E  GF  +++                 N     +++   + R  T+ +  N +NR     
Sbjct: 828  EHGGFVSIISVFISLESSFSPNRKDSRNWDMEKLELIESICRCTTSALCGNVINRENFEQ 887

Query: 751  IISSQTFLDLLSESGLLCVDHENQVIQLMLELALEIVIPPFLASEGLTKSNAIENESSHN 810
             I  +TF   L  +G+L  +    V+  + ++  E       AS+ ++    I N  S N
Sbjct: 888  QIGYKTFSSCLIMTGVLGTEFSKSVVDFIFDMVTE----NLNASDQISNQMIINNVESFN 943

Query: 811  LLLTPSGPINPDKERVYNAGAVRVLIRSLLLFTPMVQLKLLDLIEKLARAGPFNQESLTS 870
            ++L     I P  E                      +L+++  I K+A  G +NQE+L+ 
Sbjct: 944  VILD----IIPHIE------------------NKDFRLQIISRINKMAEYGRYNQEALSK 981

Query: 871  VGCVELLLETI-HPFXXXXXXXXXYALKIVEVLGSYRLSASELRMLIRYVLQMRMKNSGH 929
            +   + +L                  L +++ +G+  LS SELR  ++    ++ ++S  
Sbjct: 982  LSIPDWILSRFPSNLSNANDPLQPLLLSLIQTVGANCLSGSELRQFVKL---LQPEHSPE 1038

Query: 930  IIVEMMEKLILMGDVASENISLAPFVEMDMSKIGHAAIQVSLGERSWPPAAGYSFVCWFQ 989
            ++++++  +       +++    P+ E ++SKI    I+V + ER+WPP  GY+ + W  
Sbjct: 1039 VLLKILSSM-------AKSPPTPPYFEFNLSKIPFGYIRVPITERAWPPTNGYTIMFWLY 1091

Query: 990  FRNF--LKSQSKDTDVSKFASSKKRSGSSGLHERHILRIFSVGATNNDNATYAELYLQED 1047
               F  + + + + + S  +++   S ++  +  +  +I  V   ++D  +   +YL+ +
Sbjct: 1092 IDKFPTVNNNNNNNNSSNNSNNSNNSNNNNNNNNNNDQIDLVHIYSDDKKSSLYIYLK-N 1150

Query: 1048 GVLT--LATSNXXXXXXXXXXXXXXRWHHLAVIHSKPNALAGLFQASFAYVYLNGKLRHT 1105
            G++T  +  S+              +W+H+ ++H++      L   +   ++++G L++T
Sbjct: 1151 GIITVNIINSSKYVIEIPSYKFVEGKWYHIGIVHAR-----RLLGGTDFKLFVDGFLKYT 1205

Query: 1106 GKLGYSPC--PPGKQLQVTIGTSVGNARVSDLTWKLRSCYLFEEVLSPGCICFMYILGRG 1163
                  P     G  L   IG S  N   +D  W++ + YL E+ L    I  +Y LG  
Sbjct: 1206 ATKAQYPAQITSGSMLICDIGVSNQNRFPTDSIWRIGTFYLLEDSLGAKHINTIYFLGPN 1265

Query: 1164 YRGLFQDTDLLQFVPNQAC----GGGSMAILDSLDADVTLAANGQRLDAASKQGDLKADG 1219
            Y   F+     +F P Q          MAI D              LD   + G L    
Sbjct: 1266 YASNFKG----RFSPYQTYEIVNSANLMAIKD--------------LDYGDQLGPLN--- 1304

Query: 1220 SGIVWDLERLGNLSLQLSGKKLIFAFDGTSTEFIRSSGSFSML------NLVDPMS---- 1269
                     L  +S+Q+   K++      S + IR++ S  ++       +++ +S    
Sbjct: 1305 ---------LAKVSMQIDENKILVGL-CASNKLIRTNNSSKVVYNEIFNGIINELSQNHG 1354

Query: 1270 ----AAASPIGGIPRL---------------------------------------GRLCG 1286
                  +SP G  P L                                       G L G
Sbjct: 1355 VALNVFSSPNGTSPNLTGLQNNNNNNNNSGGSNSKKDLEGRVEIINQADLTTKLRGVLIG 1414

Query: 1287 DIYICKQGVIGETIRPIGGMELVLALVEAAETRDMLHMALTLLACALHQNPQNLKDMQIY 1346
             +   ++  + ++I+ IGGM + L L+E A + + L  +L LL   +  +P N  +M   
Sbjct: 1415 SVEAFRRNKVADSIKKIGGMPISLLLLEKANSEETLFDSLGLLVGLIQYHPTNTHEMSQI 1474

Query: 1347 RGYHLLALFLRRRMS--LFDMQSLEIFFQIAACEASFS 1382
             GY LLA  L+++ S  LF+   LE+ F +     + S
Sbjct: 1475 NGYELLAWVLKKKASLGLFNSNILELLFDLIGINGNCS 1512



 Score = 66.6 bits (161), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 100/464 (21%), Positives = 183/464 (39%), Gaps = 89/464 (19%)

Query: 2075 VLDFIAEVLSDFVTEQVKASQLIENILESVHLYVDGESVLVFQGLCLSRFINFXXXXXXX 2134
            V+ F+ +++   + +  KA  +IE +LE        E  +++    L   +         
Sbjct: 2129 VVKFLCQIMLSAMRKTSKAISIIEMVLEGAPTTATDEEFILYHSRILLDLMYVVETNITK 2188

Query: 2135 XXXXXXXXXXXIRWSTNLDALCWMIVDRVYMGSFPQPSGVLKTLEFLLSMLQLANKDGRI 2194
                        R  +NL  L  M+VDRV +    + + ++      L ++++  K   +
Sbjct: 2189 TEFFDNE-----RVHSNLIKLSSMLVDRVNLDQLVKNNKIIIAKRIFLFIVKILEK---L 2240

Query: 2195 EEAAPGGKRLLSISRGNKQLEAYIHSILKNTNRMILYCFLPSFLVSIGEDDXXXXXXXXN 2254
            E    G             L+  + S+ K+ NR+ILY      L++   D          
Sbjct: 2241 EADRVG-------------LQKTVQSLYKSLNRIILY------LINHTTDTDLSF----- 2276

Query: 2255 EXXXXXXXXXXXXXXXXXXXTVLQLLVAHRRIIFCPSNIDTDLNCCLCVNLISL-LCDKR 2313
                                 V   ++ H+RIIF  +N+D+D     C  L  L + D+ 
Sbjct: 2277 ---------------------VANHIINHQRIIFSENNLDSDFMNAFCYPLYKLVISDQH 2315

Query: 2314 QNVQNITIDVFKYLL-------VHRRAALEDLLVSRPNQGQQLDV--LHGGFDKLLTRSL 2364
            ++V N +I +++ LL       +   A +  L VS  +  +Q ++  L  GF+ L   S 
Sbjct: 2316 EHVDN-SIKLWRLLLSLKTSSYIESLATVLQLKVSSGSNQRQSEIIDLKPGFELLRNTSG 2374

Query: 2365 S------EFFEWYQNIEQVVNKVLEQCAGIMWVQYIAGSAKFPGVR-IKGMEGRRKKEMG 2417
            +      EF  W  +  Q + +V E+      + +     K      +  ++ RR + + 
Sbjct: 2375 NGAFNNDEFKLWINDNIQTITQVFEENPKKQHLSFKNNEKKHSSEHTLPSLKSRRTERLS 2434

Query: 2418 RKSREAAKLDLRHWEQVNER--RYALDLVRDTMSTELRVVRQDKYGWILHAESEWQCHLQ 2475
            +K R+  K D  H E+ ++   + A   VR + S   + ++Q +         +W+    
Sbjct: 2435 KKQRQDRK-DQSHQEEKSKHITKKAQYFVR-SESDRRKKIKQLESDKQKFNAIQWENMRA 2492

Query: 2476 QLVHERGIF------PLSKSSFSEEPEWQLCPIEGPYRMRKKLE 2513
            Q+  ER ++      PL K        W+L   EGPYRMRKK+E
Sbjct: 2493 QITRERAVWGPSEPHPLDK--------WKLDSTEGPYRMRKKME 2528



 Score = 57.4 bits (137), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/133 (23%), Positives = 68/133 (51%)

Query: 386 KDLEAVQMLQDILIKADSWKLQAEVLNRLFKIFSGHIENYSLCQQLRTVPLLILNMAGFP 445
           K+  A ++L+   +K++  + + ++L+R+  ++S +  N+ L Q   T+   I       
Sbjct: 498 KNGNAFKVLERYFLKSNYEENRVKILDRILSVYSSNTVNFILLQHTSTLTKFIQEYESLS 557

Query: 446 SHLQEIILKILEYAVTVVNCVPXXXXXXXXXXXXXPITSALKQTILSFFVKLLSFDQQYK 505
           + L+  ++KI+ + VTV+NCVP               +    + I      L++F+ +YK
Sbjct: 558 NGLKYHVMKIVCFVVTVLNCVPFQELSTFSLLVGENPSFYTLEMINQLITTLVNFEFRYK 617

Query: 506 KVLREVGVLEVML 518
            + RE G+L++++
Sbjct: 618 HIFRETGLLDILV 630

 Score =  486 bits (1252), Expect = e-136,   Method: Compositional matrix adjust.
 Identities = 292/768 (38%), Positives = 410/768 (53%), Gaps = 88/768 (11%)

Query: 2673 EKIRFKYNCERVISLDKHDGIFLIGEFSLYVIENFYIDDSG-CFCEKECEDELSVIDQAL 2731
            EK+  K++   V      +G+ L G    Y+ ENF +  +G  +C + C   +S      
Sbjct: 2388 EKVTQKFSLVIVQGHLVSEGVLLFGHQHFYICENFTLSPTGDVYCTRHCLSNISDPFIFN 2447

Query: 2732 GVKKDVSGSVDFQSKSTLSWSTPAKSLVGGRAWAYSGGAWGKEKVHSSGNLPHPWRMWKL 2791
               KD         +ST  +S                      + HS  ++         
Sbjct: 2448 LCSKD---------RSTDHYSC---------------------QCHSYADM--------- 2468

Query: 2792 DSVHEILKRDYQLRPVAIEIFSMDGCNDLLVFHKKEREEVFKNLVAINLPRNSMLDTTIS 2851
                E+ +  + L+ +A+EIF  +G +  LVF+  +R + FK+  +           ++ 
Sbjct: 2469 ---RELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQ--------PSLK 2517

Query: 2852 GSSKQESNEGSRLFKIMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYSDLTQYPVFPWVL 2911
            G +  E     R +    +   ++WQ  +ISNF+YLM+LNT AGR  +D  QYPVFPWVL
Sbjct: 2518 GKATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVL 2577

Query: 2912 ADYESENLDLSNPKTFRRLDKPMGCQTPEGEDEFRKRYESWDDPE---VPKFHYGSHYSS 2968
            ADY SE L+L+NPK FR L KPMG QT E + +F +R++  +  E     + HY +HYSS
Sbjct: 2578 ADYTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSS 2637

Query: 2969 AGIVLFYLLRLPPFSTENQKLQGGQFDHADRLFNSIRDTWLSAAGKGNTSDVKELIPEFF 3028
            A IV  YL+R+PPF+     LQGG FD ADR+F+S++ TW SA+ + N SDV+EL PEFF
Sbjct: 2638 AIIVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESAS-RENMSDVRELTPEFF 2696

Query: 3029 YMPEFLENRFNLDLGEKQSGEKVGDVVLPLWAKGSAREFISKHREALESNYVSENLHHWI 3088
            Y+PEFL N   ++ G  Q G  +GDV LP WA G  R+FIS HR+ALES++VS NLHHWI
Sbjct: 2697 YLPEFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWI 2756

Query: 3089 DLIFGYKQRGKAAEESVNVFYHYTYEGSVDIDSVTDPAMKASILAQINHFGQTPKQLFLK 3148
            DLIFGYKQ+G AA ++VN+F+ Y Y   +D+ S+TDP +K++IL  +++FGQ PKQLF K
Sbjct: 2757 DLIFGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTK 2816

Query: 3149 PHVKRRTDRK------------LPPHPLK--------HSSHLAAHEIR----KSSSP--- 3181
            PH  R    K            LP HP            S +   ++      S SP   
Sbjct: 2817 PHPARTAAGKPLPGKDVSTPVSLPGHPQPFFYSLQSLRPSQVTVKDMYLFSLGSESPKGA 2876

Query: 3182 ITQIVTLNDKILIAGTNNLLKPRTYTKYVAWGFPDRSLRFISYEQDKLLSTHENLHGGNQ 3241
            I  IV+    IL    N +L P  + +  +WGF D S    SY  DK+L T ENL    +
Sbjct: 2877 IGHIVSTEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGR 2936

Query: 3242 IQCASVSHDGHILVTGADDGLVNVWRVS--KFGPRALRRLKLEKPLCGHTAKITCLQVSQ 3299
              CA V      +VT     +V VW +S  K  PR LR   L + L GHT  +TCL  S 
Sbjct: 2937 CLCA-VCPSPTTIVTSGTSTVVCVWELSMTKGRPRGLR---LRQALYGHTQAVTCLAASV 2992

Query: 3300 PYMLIVSGSDDCTVIIWDLSSMAFVRQLPEFPASVSAIYVNDLTGEIVTAAGILLAVWSI 3359
             + L+VSGS DCT I+WDL  +  V +LP     +SAI ++D++G IV+ AG  L++W++
Sbjct: 2993 TFSLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNV 3052

Query: 3360 NGDCLALIKASQLPSDSILSVTSSTFSDWLDTKWYATGHQSGAVKVWQ 3407
            NG  LA I  +  P  +I          W  ++   TG Q G V+VW+
Sbjct: 3053 NGQPLASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWK 3100

 Score =  442 bits (1138), Expect = e-123,   Method: Compositional matrix adjust.
 Identities = 281/775 (36%), Positives = 412/775 (53%), Gaps = 78/775 (10%)

Query: 2669 LEPFEKIRFKYNCERVISLDKHDGIFLIGEFSLYVIENFYIDDSGCFCEKECEDELSVID 2728
            +E  + I+  YN  R+  L+  +GI L+G+  LY+++NF++           ++E+    
Sbjct: 1734 IESGDSIQDVYNVSRIFGLEATEGILLLGKQYLYLMDNFFL---------RSDNEI---- 1780

Query: 2729 QALGVKKDVSGSVDFQSKSTLSWSTPAKSLVGGRAWAYSGGAWGKEKVHSSGNLPHPWRM 2788
                        VD    S +    P   L+  ++ + SG      KV    +  + W  
Sbjct: 1781 ------------VDVNDNSIIDERDPYLQLLHLQSLSSSG------KVRRHISKENNWH- 1821

Query: 2789 WKLDSVHEILKRDYQLRPVAIEIFSMDGCNDLLVF-HKKEREEVFKNLVA----INLPRN 2843
            W    +  +LKR Y LR V +E+F  DG + L +  + K R+ +++ LVA     ++   
Sbjct: 1822 WDFIDLSLVLKRFYLLRDVGLELFFKDGRSFLTILSNTKNRDSLYQKLVARAPGADVLST 1881

Query: 2844 SMLDTTISGSSKQESNEGSRLFKIMAKSFS--------KRWQNGEISNFQYLMHLNTLAG 2895
            S   T++S    + + + + L   +A + S        KRW+  EISNF YL  +NTLAG
Sbjct: 1882 SHFATSMSRDLGKANGKSNFLSSKLANALSFSTTHPATKRWERREISNFNYLQIVNTLAG 1941

Query: 2896 RGYSDLTQYPVFPWVLADYESENLDLSNPKTFRRLDKPMGCQTPEGEDEFRKRYE---SW 2952
            R Y+DLTQYPVFPWV+ADY S+ LDL+NPKT+R   KPMG Q PE E +F +RY+     
Sbjct: 1942 RTYNDLTQYPVFPWVIADYTSKELDLNNPKTYRNFCKPMGAQHPERESQFNERYDLLLGL 2001

Query: 2953 DDPEVPKFHYGSHYSSAGIVLFYLLRLPPFSTENQKLQGGQFDHADRLFNSIRDTWLSAA 3012
            +D +   FHYG+HYSSA IV  YL+RL PF      LQGGQFDHADRLF SI   W S++
Sbjct: 2002 NDSQQQPFHYGTHYSSAMIVCSYLIRLRPFVDSYLALQGGQFDHADRLFYSIEQAWRSSS 2061

Query: 3013 GKGNTSDVKELIPEFFYMPEFLENRFNLDLGEKQS-GEKVGDVVLPLWAKGSAREFISKH 3071
             K N +DV+ELIPEFFY+ E   N    D G +Q     + DV+LP WAKG    F+ K+
Sbjct: 2062 -KENMADVRELIPEFFYLSEMFINGNGFDFGSRQKESTPINDVILPPWAKGDPAIFVQKN 2120

Query: 3072 REALESNYVSENLHHWIDLIFGYKQRGKAAEESVNVFYHYTYEGSVDIDSVTDPAMKASI 3131
            REALES YVS +LH WIDL+FG KQRG  A  + NVF+H +Y+G++D++++ +    A+ 
Sbjct: 2121 REALESKYVSAHLHEWIDLVFGCKQRGDEAVAATNVFHHLSYQGAIDLENIENEFELAAA 2180

Query: 3132 LAQINHFGQTPKQLFLKPHVKRR---TDRKLPPHPLKHSSHLAAHEIRKSSSPITQIVTL 3188
            +  I++FGQTPKQ+F KPH +R    TD  L P+        + H + +S SPI +I   
Sbjct: 2181 VGIIHNFGQTPKQVFKKPHPQRGPDFTDTPLGPYLFGRFED-SIHLLFQSCSPIIRICKK 2239

Query: 3189 NDKI----------LIAGTNNLLKPRTYTKYVAWGFPDRSLRFISYEQDKLLSTHENLHG 3238
               I            A     L P T   ++AWG  D +++ IS + DK     E LH 
Sbjct: 2240 VAHIQYDPSKDEVGAFAADYTPLGPNT---FLAWGRVDNTVQLISDQLDKQPVMFEELHS 2296

Query: 3239 GNQIQCASVSHDGHILVTGADDGLVNVWRVSKFGPRALRRLKLEKPLCGHTAKITCLQVS 3298
                    V+ D    +T + D  + +W +S   P    +  L++ L GH  +ITC+ V 
Sbjct: 2297 EKITHV--VACDERTFLTASLDLTLRLWTLSTNKP---IKASLKRVLYGHRYRITCVTVC 2351

Query: 3299 QPYMLIVSGSDDCTVIIWDLSSMAFVRQLPEFPASVSAIYVNDLTGEIVTAAGILLAVWS 3358
            + + +IVSG     +IIWDL+   FV  L  +   +  I VN    EI  + G    V +
Sbjct: 2352 KAFSIIVSGDAGGNLIIWDLNRAEFVSSLSVYKLPIQTIAVNARNAEIAFSTGFYCCVVN 2411

Query: 3359 INGDCLALIKASQLPSD-SILSVTSSTF-----SDWLDTKWYATGHQSGAVKVWQ 3407
            +NG  L   K S++ ++ S  ++  S F     S+WL    + TGH  G +++W+
Sbjct: 2412 VNGKILVKDKLSRIYNENSDENILCSCFYTGANSEWLHKNLFITGHPDGIIRIWE 2466