Query: CNT0025457
Subject: sp|Q8GY23|UPL1_ARATH E3 ubiquitin-protein ligase UPL1 OS=Arabidopsis

thaliana GN=UPL2 PE=1 SV=3

 Score = 1098 bits (2839), Expect = 0.0,   Method: Compositional matrix adjust.
Identities = 681/1497 (45%), Positives = 858/1497 (57%), Gaps = 125/1497 (8%)

Query: 2187 LRLEEGINGINVFDHIEVFGGSNNLSG--DTLRVMPL------DIFGTRR----QGRSTS 2234
+R E ++G+ DH ++ G S +G D + P D+F RR + R +
Sbjct: 2219 VRWREALDGL---DHFQIVGRSGGGNGFIDDITAEPFEGVNVDDLFALRRSLGFERRRQT 2275

Query: 2235 IYNLLGRAGD--HGVFDHPLLEEPSSVLHLPQQRQQENLVE------------------- 2273
+ R+G HG F HPL PS + +
Sbjct: 2276 GRSSFDRSGSEVHG-FQHPLFSRPSQTGNTASVSASAGSISRHSEAGSYDVAQFYMFDSP 2334

Query: 2274 -MAFSDRNHDNSSSRL----------DAIFRSLRSGRSGHRFNMWLDDSPQRTGSAAPAV 2322
+ F D S RL D + S R G + W D + S + ++
Sbjct: 2335 VLPFDQVPVDPFSDRLGGGGAPPPLTDYSVVGMDSSRRGVGDSRWTDVGHPQPSSLSASI 2394

Query: 2323 PEGIEELLVSQLRRPTP-EQPDEQSTPAGGAEENDQSNQQHLHQSETEAG-GDAPTEQNE 2380
+ IEE ++ LR P + E+ T +E Q + SET G G+ EQ+E
Sbjct: 2395 AQLIEEHFITNLRASAPVDTVVERETNTTEVQEQQQPDVPPSVGSETVLGDGNEGGEQSE 2454

Query: 2381 NNDNAVTPAARSELDGSESADPAPPS---NALQREVSGASEHATEMQYERSDAVVRDVEA 2437
++ L+ +E P P + N + R G A Q +R EA
Sbjct: 2455 EHE---------LLNNNEVMHPLPLNSTPNEIDRMEVGEGGGAPIEQVDR--------EA 2497

Query: 2438 VSQASSGSGATLGESLRSLEVEIGSVEGHDDGDRHGASDRLPLGDLQAASRSRRPPGSVV 2497
V SS G + ++++ V DD D S+ P D+ +S SV
Sbjct: 2498 VHLISSAQGQSDTSGIQNVSV-TAIPPPVDDPD----SNFQPSVDVDMSSDGAEGNQSVQ 2552

Query: 2498 LGSSRDISLESVSEVPQNQNQESDQNADEGDQEPNRAADTDSIDPTFLEALPEDLRAEVL 2557
S D +S + Q+ +D+ DEG + RA + ++IDPTFLEALPEDLRAEVL
Sbjct: 2553 -PSPLDGDNNELSSMEATQDVRNDEQVDEGSLD-GRAPEVNAIDPTFLEALPEDLRAEVL 2610

Query: 2558 SSRQNQVTQTSNEQPQNDGDIDPEFLAALPPDIREEVXXXXXXXXXXXSQELEGQPVEMD 2617
+S+Q Q Q +P + DIDPEFLAALPP+I+ EV Q+ +GQPV+MD
Sbjct: 2611 ASQQAQSVQPPTYEPPSVDDIDPEFLAALPPEIQREVLAQQRAQRML--QQSQGQPVDMD 2668

Query: 2618 AVSIIATFPSEIREEVXXXXXXXXXXXXXXXXXXXXNMLRERFAHRYHSGS-LFGMNXXX 2676
SIIAT P+++REEV MLR+R Y + S +FG
Sbjct: 2669 NASIIATLPADLREEVLLTSSEAVLAALPPPLLAEAQMLRDRAMRHYQARSRVFG--SSH 2726

Query: 2677 XXXXXXXXXXXXXXXLDRNAGD-------SSRQPTSKPIETEGSPLVDKDALKALIRLLR 2729
++R G SS K E EG PLV+ DALK+LIRLLR
Sbjct: 2727 RLNNRRNGLGYRLTGMERGVGVTIGQRDVSSSADGLKVKEIEGDPLVNADALKSLIRLLR 2786

Query: 2730 VVQPLYKGQLQRLLLNLCAHRESRKSLVQILVDMLMLDLQGSSKKSIDATEPPFRLYGCH 2789
+ QPL KG LQRLLLNLCAH +R +LVQ+L+DM+ +++ + S A P RLYGC
Sbjct: 2787 LAQPLGKGLLQRLLLNLCAHSFTRANLVQLLLDMIRPEME--TLPSELALTNPQRLYGCQ 2844

Query: 2790 ANITYSRPQSTDGVPPLVSRRVLETLTYLARNHPNVAKLLLFLEFPCPPTCHAETSDQRR 2849
N+ Y R Q +G+PPLV RRVLE LTYLA NH VA +L + + + R+
Sbjct: 2845 LNVVYGRSQLLNGLPPLVFRRVLEVLTYLATNHSAVADMLFYFD-----SSLLSQLSSRK 2899

Query: 2850 GK-AVLMEGDSEQNAYAXXXXXXXXXXXXYMRSVAHLEQLLNLLEVVMLNAENEI----- 2903
GK V E DS ++S +HL ++ LL+VV+ A + I
Sbjct: 2900 GKEKVTHETDSRDLEIPLVVFLKLLNRPQLLQSTSHLALVMGLLQVVVYTAASRIEGWSP 2959

Query: 2904 TQAKLEAASEKPSGPENATQDAQEXXXXXXXXXXXXXXEDSSKLPPVDGESSLQKVLQSL 2963
+ E KP G E +++ ++ E L + L
Sbjct: 2960 SSGVPEKLENKPVGEEASSETQKDAESELSVARRKNCAE-------------LYNIFLQL 3006

Query: 2964 PQAELRLLCSLLAHDGLSDNAYLLVAEVLKKIVALAPFFCCHFINELAHSMQNLTLCAMK 3023
PQ++L LC LL ++GLSD Y L EVLKK+ A+ F EL+ L+ ++
Sbjct: 3007 PQSDLCNLCMLLGYEGLSDKIYSLAGEVLKKLAAVDVTHRKFFTKELSELASGLSSSTVR 3066

Query: 3024 ELHLYEDSEKALLSTSSANGTAILRVVQALSSLVTTLQEKK-DPDHPAEKDHSDALSQIS 3082
L ++K +T S G +ILRV+Q LSSL +T+ + D +++ + + +
Sbjct: 3067 VLATLSTTQKMSQNTCSMAGASILRVLQVLSSLTSTIDDSNVGTDKETDQEEQNIMQGL- 3125

Query: 3083 EINTALDALWLELSNCISKIESSSEYXXXXXXXXXXXXXXXXGVAPPLPAGTQNILPYIE 3142
AL+ LW EL CIS E ++ L GTQ++LP IE
Sbjct: 3126 --KVALEPLWQELGQCISMTELQLDHTAATSNVNPGDHVLGISPTSSLSPGTQSLLPLIE 3183

Query: 3143 SFFVTCEKLRPGQPDAIQEASTSDMEDAXXXXXXXXXXXXHANLDEKHNA---FVKFSEK 3199
+FFV CEK++ P +Q+ +T + + +K + F KF EK
Sbjct: 3184 AFFVLCEKIQ--TPSMLQQDATVTAGEVKESSTHGSSSKTIVDSQKKIDGSVTFSKFVEK 3241

Query: 3200 HRRLLNAFIRQNPGLLEKSFSLMLKIPRLIEFDNKRAYFRSKIKHQHDHHHS-PVRISVR 3258
HRRLLN+F+RQNP LLEKSFS+MLK PRLI+FDNK+AYFRS+I+HQHD H S P+RISVR
Sbjct: 3242 HRRLLNSFVRQNPSLLEKSFSMMLKAPRLIDFDNKKAYFRSRIRHQHDQHISGPLRISVR 3301

Query: 3259 RAYILEDSYNQLRMRSPQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT 3318
RAY+LEDSYNQLRMRSPQDLKGRL V FQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT
Sbjct: 3302 RAYVLEDSYNQLRMRSPQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT 3361

Query: 3319 TVGNDLTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTY 3378
TVGND TFQPNPNSVYQTEHLSYFKFVGR+V KALFDGQLLDV+FTRSFYKHILGVKVTY
Sbjct: 3362 TVGNDATFQPNPNSVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVKVTY 3421

Query: 3379 HDIEAIDPAYYKNLKWMLENDISDVLDLSFSMDADEEKRILYEKAEVTDYELIPGGRNIK 3438
HDIEA+DP YYKNLKW+LEND+SD+LDL+FSMDADEEK ILYEK EVTDYEL PGGRNI+
Sbjct: 3422 HDIEAVDPDYYKNLKWLLENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNIR 3481

Query: 3439 VTEENKHEYVNRVAEHRLTTAIRPQITSFMEGFNELIPEELISIFNDKELELLISGLPDI 3498
VTEE KHEYV+ VA+H LT+AIRPQI +F+EG NELIP EL+SIFNDKELELLISGLP+I
Sbjct: 3482 VTEETKHEYVDLVADHILTSAIRPQINAFLEGLNELIPRELVSIFNDKELELLISGLPEI 3541

Query: 3499 DLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGI 3558
D DDLKANTEY+ Y++ SPVI+WFWE+V+ FSKED ARFLQFVTGTSKVPLEGF ALQGI
Sbjct: 3542 DFDDLKANTEYTSYTVGSPVIRWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGI 3601

Query: 3559 SGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKEQLQERLLLAIHEANEGFGFG 3615
SGPQR QIHKAYGS LPSAHTCFNQLDLPEY SKEQ+QERLLLAIHEANEGFGF
Sbjct: 3602 SGPQRLQIHKAYGSPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIHEANEGFGFA 3658



Score = 1019 bits (2635), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 725/2122 (34%), Positives = 1076/2122 (50%), Gaps = 215/2122 (10%)

Query: 36 SEPPAKVKAFIDRVISIPLHDIAIPLSGFRWEFNKGNFHHWKPLFMHFDTYFKTQISSRK 95
SE P K+ FI+ V S+PL I PL+ FRWEF+KG+FHHW LF HFDT+F+ + RK
Sbjct: 9 SEVPTKISLFINSVTSVPLELIQEPLASFRWEFDKGDFHHWVDLFYHFDTFFEKHVKVRK 68

Query: 96 DLLLSDDMAEGDP-LPKNTILQILRVMQIVLENCQNKTSFAGLE-HFRLLLASSDPEIXX 153
DL + ++ E DP PK+ +LQ+LRV+++VLENC NK + E H LLLAS+D ++
Sbjct: 69 DLRIEEEFDESDPPFPKDAVLQVLRVIRLVLENCTNKQFYTSYEQHLSLLLASTDADVVE 128

Query: 154 XXXXXXXXXXKINPSKLHMNGKLINCGAINSHLLSLAQGWGSKEEGLGLYSCVVANERNQ 213
K K I ++N L SLAQGWG KEEGLGL SC
Sbjct: 129 ACLQTLAAFLKRPTGKYS-----IRDASLNLKLFSLAQGWGGKEEGLGLTSCAT------ 177

Query: 214 QEGLCLFPADMENKYDGTQHRLGSTLHFEYNLAPAQDPDQSSDKAKPSNLCVIHIPDLHL 273
E+ D +LG TL FE+ A + P + P L VIH+PD+ +
Sbjct: 178 -----------EHSCDQLFLQLGCTLLFEF-YASDESPSE-----LPGGLQVIHVPDVSM 220

Query: 274 QKEDDLSILKQCVDKFNVPSEHRFSLFTRIRYAHAFNSPRTCRLYSRISLLAFIVLVQSS 333
+ E DL +L + V NVP RF+L TR+R+A AF+S T + Y+ I L AFIVLVQ+S
Sbjct: 221 RSESDLELLNKLVIDHNVPPSLRFALLTRLRFARAFSSLATRQQYTCIRLYAFIVLVQAS 280

Query: 334 DAHDELTSFFTNEPEYINELIRLVRSEEFVPGPIRXXXXXXXXXXXXXXXSSHERARXXX 393
+ + SFF EPE++NEL+ LV E+ VP IR S +R R
Sbjct: 281 GDTENVVSFFNGEPEFVNELVTLVSYEDTVPAKIRILCLQSLVAL------SQDRTRQPT 334

Query: 394 XXXXXXXXXNRMVLLSVLQKAIXXXXXXXXXXXXXIVDAXXXXXXXXXXXXXXXGTTVRG 453
+R +L ++QKAI +A + +R
Sbjct: 335 VLTAVTSGGHRGLLSGLMQKAIDSVICNTSKWSLAFAEALLSLVTVLVSSSSGC-SAMRE 393

Query: 454 SGMVXXXXXXXQDNDPSHMHLVCLAVKTLQKLMEYSSPAVSLFKDLGGVELLSQRLHVEV 513
+G++ +D DP H+HLV AV L+ M+YS+PA +LF+DLGG++ RL EV
Sbjct: 394 AGLIPTLVPLIKDTDPQHLHLVSTAVHILEVFMDYSNPAAALFRDLGGLDDTIFRLKQEV 453

Query: 514 QRVIGVDSHNSMVTSDALKSEEDHL-----------YSQKRLIKALLKALGSATYSPANP 562
R D +V ED Y ++ L+KALL+A+ TY+P N
Sbjct: 454 SRT--EDDVKEIVCCSGSNGPEDDTEQLPYSEALISYHRRLLLKALLRAISLGTYAPGN- 510

Query: 563 ARSQSSNDNSLPISLSLIFQNVDKFGGDIYFSAVTVMSEIIHKDPTCFPSLKELGLPDAF 622
S ++ LP L +IF+ FGG ++ A TVMS++IHKDPTCF +L GL AF
Sbjct: 511 TNLYGSEESLLPECLCIIFRRAKDFGGGVFSLAATVMSDLIHKDPTCFNALDSAGLTSAF 570

Query: 623 LSSVSAGVIPSCKALICVPNGLGAICLNNQGLEAVRETSALRFLVDTFTSRKYLIPM-NE 681
L ++S VI S +A+ C+P L A+CLNN GL+AV++ +ALR V F+S YL + ++
Sbjct: 571 LDAISDEVICSAEAITCIPQCLDALCLNNSGLQAVKDRNALRCFVKIFSSPSYLKALTSD 630

Query: 682 GXXXXXXXXXXXXRHVQSLRSTGVDIIIEIINKLSSPREDKSNEPAASSDERTE-----M 736
RH SLR+ GVD+ IEI+N + + S+D T+ M
Sbjct: 631 TPGSLSSGLDELLRHQSSLRTYGVDMFIEILNSILIIGSGMEATTSKSADVPTDAAPVPM 690

Query: 737 ETDAEGRDLVSAMDSSEDGT-----NDEQFSHLSIFHVMVLVHRTMENSETCRLFVEKGG 791
E D + + L + D +E + N E F + +V L ++N+E C LFVEK G
Sbjct: 691 EIDVDEKSL-AVSDEAEPSSDTSPANIELFLPDCVCNVARLFETVLQNAEVCSLFVEKKG 749

Query: 792 XXXXXXXXXRP------SITQS------------SGGMPIALHS--------TMELDTVA 825
P S+ QS S G+ L S T L
Sbjct: 750 IDTVLQLFSLPLMPLSTSLGQSFSVAFKNFSPQHSAGLARILCSYLREHLKKTNNLLVSI 809

Query: 826 SSGEVAKLEKGAIPSXXXXXXXXXXAASKDNRWMN---ALLSEFGDSSRDVLEDIGRVHR 882
++ KLE S N + +++SE ++ DVL+++G ++
Sbjct: 810 EGTQLLKLESAVQTKILRSLSCLEGMLSLSNFLLKGSASVISELSAANADVLKELGITYK 869

Query: 883 EVLWQISLFEEKKVEPETSSPLANDSQQDAAV------GDVDDSRYTSFRQYLDPLLRRR 936
+ +WQ++L + K + + S A+D+ A+ D D S + R Y +P+ R
Sbjct: 870 QTIWQMALCNDTKEDEKKSVDRASDNSVSASSSTAERESDEDSSNALAVR-YTNPVSIRS 928

Query: 937 GSGWNIESQVSDLINIYRDIGRAAGDSQRYPSAGLPXXXXXXXXXXXXXXX-------XX 989
S +I + +++ R GR R+ A +
Sbjct: 929 SSSQSIWGGHREFLSVVRS-GRGVHGHTRHAIARMRGGRTRRHLESFNFDSEIPADLPVT 987

Query: 990 TKSEEDKKRSEHSSCCDMMRSLSYHINHLFMELGKAMLLTSRRENSPXXXXXXXXXXXXX 1049
+ S E KK+S +++ L+ + F L K +RR
Sbjct: 988 SSSHELKKKSTEVLIAEILNKLNCTLRFFFTSLVKGFTSANRRRIDGPSLSSASKTLGTA 1047

Query: 1050 XXXXXXEHLNFEGHTISSERETTVSTKCRYLGKVVEFIDGILLD-RPESCNPIMLNSFYC 1108
E LNF+G+ ++ +T++S KCRYLGKVV+ I + D R C M+NSFY
Sbjct: 1048 LAKVFLEALNFQGYGAAAGPDTSLSLKCRYLGKVVDDITFLTFDTRRRVCFTAMVNSFYV 1107

Query: 1109 RGVIQAILTTFEATSELLFSMNRLPSSPMETDSKSVKEDRETDSSWIYGPLSSYGAILDH 1168
G + +LTTFEATS+LL+ + + + KS + + + S W+ L +Y LD+
Sbjct: 1108 HGTFKELLTTFEATSQLLWKVPFSIRASSTENEKSGERNLWSHSKWLVDTLQNYCRALDY 1167

Query: 1169 LVTSSFILS-SSTRQLLEQP----IFSGNIRFPQDAEKFMKLLQSRVLKTVLPIWTHPQF 1223
V S+++LS +S QLL QP + G P++ E F++ LQS+VL+ +LPIW HP F
Sbjct: 1168 FVNSTYLLSPTSQTQLLVQPASVDLSIGLFPVPREPETFVRNLQSQVLEVILPIWNHPMF 1227

Query: 1224 PECNVELISSVTSIMRHVYSGV----EVKNTAINTGARLAGP-PPDENAISLIVEMGFSR 1278
P+CN ++SVTS++ H+YSGV E ++ A + A P PDE + +IVEMGFSR
Sbjct: 1228 PDCNPNFVASVTSLVTHIYSGVVDTRENRSGATQGTNQRALPLQPDEAIVGMIVEMGFSR 1287

Query: 1279 ARAEEALRQVGTNSVEIATDWLFSHPEEP-QEDDELARALAMSLGNSDTSAQEEDG-KSN 1336
+RAE+ALR+VGTNSVE+A DWLF++PE+P QEDDELA+ALA+SLGNS + + ED K
Sbjct: 1288 SRAEDALRRVGTNSVEMAMDWLFTNPEDPVQEDDELAQALALSLGNSSETPKLEDTEKPV 1347

Query: 1337 DLELEEETVQLPPIDEVLSSCLRLLQTKESLAFPVRDMLLTMSSQNDGQNRVKVLTYLID 1396
D+ EE + PP+DEV+++ ++L Q+ +S+AFP+ D+ +T+ ++N G++R K++ YLI
Sbjct: 1348 DVPQEEAEPKEPPVDEVIAASVKLFQSDDSIAFPLVDLFVTLCNRNKGEDRPKIVFYLIQ 1407

Query: 1397 HLKNCLMSSDPLKST-ALSALFHVLALILHGDTAAREVASKAGLVKVALNLLCSWELEPR 1455
LK L+ D K T AL+ + H+LAL+L D RE+A++ G+V VA+ +L + L+
Sbjct: 1408 QLK--LVQLDFSKDTGALTMIPHILALVLSEDDNTREIAAQDGIVAVAIGILTDFNLKSE 1465

Query: 1456 QGEISDVPNWVPSCFLSIDRMLQLDPK--------------------------LPDVTEL 1489
P + + L + MLQ + L D
Sbjct: 1466 SETDILAPKCISALLLVLSMMLQAQTRLSSEYVEGNQGGSLVLSDSPQDSTAALKDALSS 1525

Query: 1490 DVLKKDNSNTQTSVVIXXXXXXXXXXXXXTGXXXXXXXXXXXXICCKCIQKQLPSATMHA 1549
DV K +++ S+ TG I C I++++P+ M A
Sbjct: 1526 DVAKGESNQALESMF-----------GKSTGYLTMEESSKVLLIACGLIKQRVPAMIMQA 1574

Query: 1550 ILQLCATLTKLHAAAICFLESGGLHALLSLPTSSLFSGFNSVASTIIRHILEDPHTLQQA 1609
+LQLCA LTK HA AI FLE+GGL +L +LP F G+++VAS I+RH++EDP TLQ A
Sbjct: 1575 VLQLCARLTKSHALAIQFLENGGLSSLFNLPKKCFFPGYDTVASVIVRHLVEDPQTLQIA 1634

Query: 1610 MELEIRHSLVTAANRHANPRVTPRNFVQNLAFVVYRDPVIFMKAAQAVCQIEMVGDRPYV 1669
ME EIR +L + RH RV PR F+ +A V+ RDPV+FMKA + CQ+E G +V
Sbjct: 1635 METEIRQTL--SGKRHIG-RVLPRTFLTTMAPVISRDPVVFMKAVASTCQLESSGGTDFV 1691

Query: 1670 VLLXXXXXXXXXXXXXXXXXXXXXTSGAATKMTSGD---MALGSPVS-SQGKQTDLNTKN 1725
+L T SG +L P+ S+ K D + K
Sbjct: 1692 IL----------------------TKEKEKPKVSGSEHGFSLNEPLGISENKLHDGSGKC 1729

Query: 1726 VKSNRKPPQSFVTVIEYLLDLVMSFIPPPRAEDRPDGESSTASSTDMDIDSSAKGKGKAV 1785
KS+R+ P +F+ VI+ L+D+V+SF R E GE++ S D+D + + K KGK+
Sbjct: 1730 SKSHRRVPTNFIQVIDQLIDIVLSFPGLKRQE----GEAANLISMDVD-EPTTKVKGKSK 1784

Query: 1786 AVTPEESKHAIQEATASLAKSAFVLKLLTDVLLTYASSIQVVLRHDADLSNARGPNRIGI 1845
PE+++ E + LA+ F+LKLL+D++L Y V+LR D ++S RG N
Sbjct: 1785 VGEPEKAELG-SEKSEELARVTFILKLLSDIVLMYLHGTSVILRRDTEISQLRGSNLPDD 1843

Query: 1846 S--SGGVFSHILQHFLPHSTKQKKERKADGDWRYKLATRANQFLVASSIRSAEGRKRIFS 1903
S +GG+ H++ LP S ++ +W+ KL+ +A+ FLV RS EGRKRI +
Sbjct: 1844 SPGNGGLIYHVIHRLLPISLEK---FVGPEEWKEKLSEKASWFLVVLCSRSNEGRKRIIN 1900

Query: 1904 EICSIFVDFT----DSPAGCKPPILRMNAYVDLLNDILSARSPT----GSSLSAESAVTF 1955
E+ + F S P R+ A+ +L+ IL+ S + G S + A +
Sbjct: 1901 ELTRVLSVFASLGRSSSQSVLLPDKRVLAFANLVYSILTKNSSSSNFPGCGCSPDVAKSM 1960

Query: 1956 VEVGLVQYLSKTLQVIDLDHPDSAKIVTAIVKALEVVTKEHVHSADLNAKGENSSKVVSD 2015
++ G +Q L+ L VIDLDHPD+ K+VT I+K+LE +T+ NA + S+V ++
Sbjct: 1961 IDGGTIQCLTSILNVIDLDHPDAPKLVTLILKSLETLTRAA------NAAEQLKSEVPNE 2014

Query: 2016 QSNLDPSSNRFQALDTTQPTEM 2037
Q N D S R + T+ TE+
Sbjct: 2015 QKNTD-SDERHDSHGTSTSTEV 2035

Query: CNT0025457
Subject: sp|Q9P4Z1|TOM1_NEUCR E3 ubiquitin-protein ligase TOM1-like

thaliana GN=UPL1 PE=1 SV=3

 Score = 1080 bits (2793), Expect = 0.0,   Method: Compositional matrix adjust.
Identities = 598/1125 (53%), Positives = 723/1125 (64%), Gaps = 40/1125 (3%)

Query: 2509 VSEVPQNQNQESDQNADEGDQEPNRAADTDSIDPTFLEALPEDLRAEVLSSRQNQVTQTS 2568
+S + +N +D+ +EG + RA + ++IDPTFLEALPEDLRAEVL+S+Q Q Q
Sbjct: 2579 LSSMEATENVRNDEQVEEGSLD-GRAPEVNAIDPTFLEALPEDLRAEVLASQQAQSVQPP 2637

Query: 2569 NEQPQNDGDIDPEFLAALPPDIREEVXXXXXXXXXXXSQELEGQPVEMDAVSIIATFPSE 2628
+P DIDPEFLAALPPDI+ EV Q+ +GQ V+MD SIIAT P++
Sbjct: 2638 TYEPPPVDDIDPEFLAALPPDIQTEVLAQQRAQRMV--QQSQGQAVDMDNASIIATLPAD 2695

Query: 2629 IREEVXXXXXXXXXXXXXXXXXXXXNMLRERFAHRYHS-GSLFGMNXXXXXXXXXXXXXX 2687
+REEV MLR+R Y + S+FG +
Sbjct: 2696 LREEVLLTSSEAVLAALPSPLLAEAQMLRDRAMSHYQARSSVFG-SSHRLNNRRNGLGYN 2754

Query: 2688 XXXXLDRNAGD-------SSRQPTSKPIETEGSPLVDKDALKALIRLLRVVQPLYKGQLQ 2740
+DR G SS K E EG PLV+ DALK+LIRLLR+ QPL KG LQ
Sbjct: 2755 RLTGMDRGVGVTIGQRAVSSSADGLKVKEIEGDPLVNADALKSLIRLLRLAQPLGKGLLQ 2814

Query: 2741 RLLLNLCAHRESRKSLVQILVDMLMLDLQGSSKKSIDATEPPFRLYGCHANITYSRPQST 2800
RLLLNLCAH +R +LVQ+L+DM+ +++ S + A P RLYGC +N+ Y R Q
Sbjct: 2815 RLLLNLCAHSFTRANLVQLLLDMIRPEMETSPSEL--AITNPQRLYGCQSNVVYGRSQLL 2872

Query: 2801 DGVPPLVSRRVLETLTYLARNHPNVAKLLLFLEFPCPPTCHAETSDQRRGK-AVLMEGDS 2859
+G+PPLV RRVLE LTYLA NH VA +L + + + R+GK V DS
Sbjct: 2873 NGLPPLVFRRVLEVLTYLATNHSAVADMLFYFD-----SSLLSQLSSRKGKEKVTHVTDS 2927

Query: 2860 EQNAYAXXXXXXXXXXXXYMRSVAHLEQLLNLLEVVMLNAENEI-----TQAKLEAASEK 2914
++S +HL ++ LL+VV+ A + I + E K
Sbjct: 2928 RDLEIPLVVFLKLLNRPQLLQSTSHLGLVMGLLQVVVYTAASRIEGWSPSSGVPEKLENK 2987

Query: 2915 PSGPENATQDAQEXXXXXXXXXXXXXXEDSSKLPPVDGESSLQKVLQSLPQAELRLLCSL 2974
P G E +++ ++ + + + + LPQ++L LC L
Sbjct: 2988 PVGEEASSETRKDAESELVGEADLSVARRKNC-------AEIYNIFLQLPQSDLCNLCIL 3040

Query: 2975 LAHDGLSDNAYLLVAEVLKKIVALAPFFCCHFINELAHSMQNLTLCAMKELHLYEDSEKA 3034
L ++GLSD Y L EVLKK+ A+ F EL+ +L+ ++EL +K
Sbjct: 3041 LGYEGLSDKIYSLAGEVLKKLAAVDVAHRKFFTKELSELASSLSSSTVRELATLSSKQKM 3100

Query: 3035 LLSTSSANGTAILRVVQALSSLVTTLQEKKDPDHPAEKDHSDALSQISEINTALDALWLE 3094
ST S G +ILRV+Q LSSL + + E + + Q +N AL+ LW E
Sbjct: 3101 SRSTGSMAGASILRVLQVLSSLTSPIDESNVGTERETEQEEQNIMQ--RLNVALEPLWHE 3158

Query: 3095 LSNCISKIESSSEYXXXXXXXXXXXXXXXXGVAPPLPAGTQNILPYIESFFVTCEKLRPG 3154
LS CIS E ++ L GTQ +LP IE+FFV CEK++
Sbjct: 3159 LSQCISMTELQLDHTAAASNINPGDHVLGISPTSSLSPGTQRLLPLIEAFFVLCEKIQ-- 3216

Query: 3155 QPDAIQEASTSDMEDAXXXXXXXXXXXXHANLDEKHNA---FVKFSEKHRRLLNAFIRQN 3211
P +Q+ + + + +K + F KF+EKHRRLLN+FIRQN
Sbjct: 3217 TPSMLQQDTNVTAGEVKESSAHGSSSKTSVDSQKKTDGSVTFSKFAEKHRRLLNSFIRQN 3276

Query: 3212 PGLLEKSFSLMLKIPRLIEFDNKRAYFRSKIKHQHDHHHS-PVRISVRRAYILEDSYNQL 3270
P LLEKS S+MLK PRLI+FDNK+AYFRS+I+HQHD H S P+RISVRRAY+LEDSYNQL
Sbjct: 3277 PSLLEKSLSMMLKAPRLIDFDNKKAYFRSRIRHQHDQHISGPLRISVRRAYVLEDSYNQL 3336

Query: 3271 RMRSPQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDLTFQPNP 3330
RMRSPQDLKGRL V FQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGND TFQPNP
Sbjct: 3337 RMRSPQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDATFQPNP 3396

Query: 3331 NSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPAYYK 3390
NSVYQTEHLSYFKFVGR+V KALFDGQLLDV+FTRSFYKHILGVKVTYHDIEA+DP YYK
Sbjct: 3397 NSVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYK 3456

Query: 3391 NLKWMLENDISDVLDLSFSMDADEEKRILYEKAEVTDYELIPGGRNIKVTEENKHEYVNR 3450
NLKW+LEND+SD+LDL+FSMDADEEK ILYEK EVTDYEL PGGRNI+VTEE KHEYV+
Sbjct: 3457 NLKWLLENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDL 3516

Query: 3451 VAEHRLTTAIRPQITSFMEGFNELIPEELISIFNDKELELLISGLPDIDLDDLKANTEYS 3510
VA H LT AIRPQI +F+EGFNELIP EL+SIFNDKELELLISGLP+ID DDLKANTEY+
Sbjct: 3517 VAGHILTNAIRPQINAFLEGFNELIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYT 3576

Query: 3511 GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 3570
Y+ SPVI WFWE+V+ FSKED ARFLQFVTGTSKVPLEGF ALQGISGPQR QIHKAY
Sbjct: 3577 SYTAGSPVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAY 3636

Query: 3571 GSTNHLPSAHTCFNQLDLPEYTSKEQLQERLLLAIHEANEGFGFG 3615
G+ LPSAHTCFNQLDLPEY SKEQLQERLLLAIHEA+EGFGF
Sbjct: 3637 GAPERLPSAHTCFNQLDLPEYQSKEQLQERLLLAIHEASEGFGFA 3681



Score = 1023 bits (2645), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 717/2106 (34%), Positives = 1077/2106 (51%), Gaps = 206/2106 (9%)

Query: 36 SEPPAKVKAFIDRVISIPLHDIAIPLSGFRWEFNKGNFHHWKPLFMHFDTYFKTQISSRK 95
SE P+K+K+FI+ V S+PL I PL+ FRWEF+KG+FHHW LF +FDT+F+ + RK
Sbjct: 9 SEVPSKIKSFINSVTSVPLELIHEPLACFRWEFDKGDFHHWVDLFNYFDTFFEKHVQVRK 68

Query: 96 DLLLSDDMAEGDP-LPKNTILQILRVMQIVLENCQNKTSFAGLE-HFRLLLASSDPEIXX 153
DL + ++ E DP PK+ +LQ+LRV+++VLENC NK ++ E H LLLAS+D ++
Sbjct: 69 DLHIEENFEESDPPFPKDAVLQVLRVIRVVLENCTNKHFYSSYEQHLSLLLASTDADVVE 128

Query: 154 XXXXXXXXXXKINPSKLHMNGKLINCGAINSHLLSLAQGWGSKEEGLGLYSCVVANERNQ 213
K K I ++NS L SLAQGWG KEEGLGL SC
Sbjct: 129 ACLQTLAAFLKRQIGKYS-----IRDASLNSKLFSLAQGWGGKEEGLGLTSCAA------ 177

Query: 214 QEGLCLFPADMENKYDGTQHRLGSTLHFEYNLAPAQDPDQSSDKAKPSNLCVIHIPDLHL 273
EN D +LG TLHFE+ P S P L VIH+PD+ +
Sbjct: 178 -----------ENSCDQVSLQLGRTLHFEFY------PSDESPSELPGGLQVIHVPDVSI 220

Query: 274 QKEDDLSILKQCVDKFNVPSEHRFSLFTRIRYAHAFNSPRTCRLYSRISLLAFIVLVQSS 333
E DL +L + V NVP RF+L TR+R+A AF+S T + ++ I L AF+VLVQ+S
Sbjct: 221 CAESDLELLNKLVIDHNVPPSLRFALLTRMRFARAFSSLATRQQFTCIRLYAFVVLVQAS 280

Query: 334 DAHDELTSFFTNEPEYINELIRLVRSEEFVPGPIRXXXXXXXXXXXXXXXSSHERARXXX 393
+ + SFF EPE++NEL+ LV E+ VP IR S +R R
Sbjct: 281 GDTENVVSFFNGEPEFVNELVTLVSYEDTVPEKIRILCLLSLVAL------SQDRTRQPT 334

Query: 394 XXXXXXXXXNRMVLLSVLQKAIXXXXXXXXXXXXXIVDAXXXXXXXXXXXXXXXGTTVRG 453
+R +L ++QKAI +A + +R
Sbjct: 335 VLTAVTSGGHRGLLSGLMQKAIDSVVCITSKWSLAFAEALLSLVTVLVSSSSGC-SAMRE 393

Query: 454 SGMVXXXXXXXQDNDPSHMHLVCLAVKTLQKLMEYSSPAVSLFKDLGGVELLSQRLHVEV 513
+G++ +D DP H+HLV AV L+ M+YS+PA +LF+DLGG++ RL +EV
Sbjct: 394 AGLIPTLVPLIKDTDPQHLHLVSAAVHILEAFMDYSNPAAALFRDLGGLDDTIFRLKLEV 453

Query: 514 QRVIGVDSHNSMVTSDALKSEEDHLYSQKRLIK--------ALLKALGSATYSPANPARS 565
R D +SD+ + + L + LI ALL+A+ TY+P N
Sbjct: 454 SRTED-DVKEKNCSSDSNGPDTEQLPYSEALISYHRRLLLKALLRAISLGTYAPGN-TNL 511

Query: 566 QSSNDNSLPISLSLIFQNVDKFGGDIYFSAVTVMSEIIHKDPTCFPSLKELGLPDAFLSS 625
S ++ LP L +IF+ FGG ++ A TVMS++IHKDPTCF +L GL FL +
Sbjct: 512 YGSEESLLPECLCIIFRRAKDFGGGVFSLAATVMSDLIHKDPTCFNALDSAGLTSTFLDA 571

Query: 626 VSAGVIPSCKALICVPNGLGAICLNNQGLEAVRETSALRFLVDTFTSRKYLIPMN-EGXX 684
+S VI S +A+ C+P L A+CLNN GL+AV++ +ALR V FTS YL + +
Sbjct: 572 ISDEVICSAEAITCIPQCLDALCLNNSGLQAVKDRNALRCFVKIFTSPSYLRALTGDTPG 631

Query: 685 XXXXXXXXXXRHVQSLRSTGVDIIIEIINK-------LSSPREDKSNEPAASSDERTEME 737
RH SLR+ GVD+ IEI+N + + ++ P +++ E++
Sbjct: 632 SLSSGLDELLRHQSSLRTYGVDMFIEILNSMLIIGSGMEATTSKSADVPTSAAPVPMEID 691

Query: 738 TDAEGRDLVSAMDSSEDGT--NDEQFSHLSIFHVMVLVHRTMENSETCRLFVEKGGXXXX 795
D + + + S D + N E F + +V L ++N+E C LFVEK G
Sbjct: 692 VDEKSLAVSDEAEPSSDTSPANIELFLPDCVCNVARLFETVLQNAEVCSLFVEKKGIDAV 751

Query: 796 XXXXXRP------SITQS------------SGGMPIALHSTM-------ELDTVASSG-E 829
P S+ QS S G+ + S + ++ V+ G +
Sbjct: 752 LQLFSLPLMPLSTSLGQSFSVAFKNFSPQHSAGLARIVCSYLREHLKKTKILLVSIEGTQ 811

Query: 830 VAKLEKGAIPSXXXXXXXXXXAASKDNRWMN---ALLSEFGDSSRDVLEDIGRVHREVLW 886
+ KLE S N + +++SE + DVL+++G +++ +W
Sbjct: 812 LLKLESAIQTKILRSLSCLEGMLSLSNFLLKGSASVISELSAADADVLKELGITYKQTIW 871

Query: 887 QISLF------EEKKVEPETSSPLANDSQQDAAVGDVDDSRYTSFRQYLDPLLRRRGSGW 940
Q++L E+K V+ + + ++ S D D S + R Y +P+ R S
Sbjct: 872 QMALCNDTKEDEKKSVDRGSDNSVSASSSTAERESDEDSSNALAVR-YTNPVSIRSSSSQ 930

Query: 941 NIESQVSDLINIYRDIGRAAGDSQRYPSAGLPXXXXXXXXXXXXXXX-------XXTKSE 993
+I + ++I R G R+ A + + S
Sbjct: 931 SIWGGDREFLSIVRS-GEGIHGRTRHAIARMRGGRTRRHLESFNFDSEIPADLPVTSSSH 989

Query: 994 EDKKRSEHSSCCDMMRSLSYHINHLFMELGKAMLLTSRRENSPXXXXXXXXXXXXXXXXX 1053
E KK+S +++ L+ + F L K +RR
Sbjct: 990 ELKKKSTEVLIAEILNKLNCTLRFFFTALVKGFTSANRRRIDGASLSSASKTLGTALAKV 1049

Query: 1054 XXEHLNFEGHTISSERETTVSTKCRYLGKVVEFIDGILLD-RPESCNPIMLNSFYCRGVI 1112
E LNF+G+ ++ E ++S KCRYLGKVV+ I + D R C M+NSFY G
Sbjct: 1050 FLEALNFDGYGAAAGHEKSLSVKCRYLGKVVDDITFLSFDTRRRVCFTAMVNSFYVHGTF 1109

Query: 1113 QAILTTFEATSELLFSMN-RLPSSPMETDSKSVKEDRETDSSWIYGPLSSYGAILDHLVT 1171
+ +LTTFEATS+LL+++ +P+S E + K + + + S W+ L +Y LD+ V
Sbjct: 1110 KELLTTFEATSQLLWTVPFSIPASSTENE-KPGERNIWSHSKWLVDTLQNYCRALDYFVN 1168

Query: 1172 SSFILS-SSTRQLLEQP----IFSGNIRFPQDAEKFMKLLQSRVLKTVLPIWTHPQFPEC 1226
S+++LS +S QLL QP + G P++ E F++ LQS+VL +LPIW HP FP+C
Sbjct: 1169 STYLLSPTSQTQLLVQPASVGLSIGLFPVPREPETFVRNLQSQVLDVILPIWNHPMFPDC 1228

Query: 1227 NVELISSVTSIMRHVYSGV---EVKNTAINTGARLAGPP--PDENAISLIVEMGFSRARA 1281
N ++SVTS++ H+YSGV + + G P DE+ + +IVEMGFSR+RA
Sbjct: 1229 NPNFVASVTSLVTHIYSGVVDARENRSGVTRGINQRALPLQLDESIVGMIVEMGFSRSRA 1288

Query: 1282 EEALRQVGTNSVEIATDWLFSHPEEP-QEDDELARALAMSLGNSDTSAQEEDG-KSNDLE 1339
E ALR+VGTNSVE+A DWLF++PE+P QEDDELA+ALA+SLGNS + + ED K D+
Sbjct: 1289 EIALRRVGTNSVEMAMDWLFTNPEQPVQEDDELAQALALSLGNSSETPKLEDTEKPVDVP 1348

Query: 1340 LEEETVQLPPIDEVLSSCLRLLQTKESLAFPVRDMLLTMSSQNDGQNRVKVLTYLIDHLK 1399
EE + PP+DEV+++ ++L Q+ +S+AFP+ D+ +T+ ++N G++R K+++YLI LK
Sbjct: 1349 QEEAEPKEPPVDEVIAASVKLFQSDDSMAFPLMDLFVTLCNRNKGEDRPKIVSYLIQQLK 1408

Query: 1400 NCLMSSDPLKST-ALSALFHVLALILHGDTAAREVASKAGLVKVALNLLCSWELEPRQGE 1458
L+ D K T AL+ + H+LAL+L D RE+A++ G+V VA+ +L + L+
Sbjct: 1409 --LVQLDFSKDTGALTMIPHILALVLSEDDNTREIAAQDGIVTVAIGILTDFNLKSESET 1466

Query: 1459 ISDVPNWVPSCFLSIDRMLQLDPKLP-------------------DVTEL--DVLKKDNS 1497
P + + L + MLQ KL D T D L D +
Sbjct: 1467 EILAPKCISALLLVLSMMLQAQTKLSSEYVEGNQGGSLVPSDSPQDSTAALKDALSSDVA 1526

Query: 1498 NTQTSVVIXXXXXXXXXXXXXTGXXXXXXXXXXXXICCKCIQKQLPSATMHAILQLCATL 1557
+++ + TG I C I++ +P+ M A+LQLCA L
Sbjct: 1527 KGESNQAL------ELIFGKSTGYLTMEEGHKALLIACGLIKQHVPAMIMQAVLQLCARL 1580

Query: 1558 TKLHAAAICFLESGGLHALLSLPTSSLFSGFNSVASTIIRHILEDPHTLQQAMELEIRHS 1617
TK HA AI FLE+GGL +L +LP F G+++VAS I+RH++EDP TLQ AME EIR +
Sbjct: 1581 TKSHALAIQFLENGGLSSLFNLPKKCCFPGYDTVASVIVRHLVEDPQTLQIAMETEIRQT 1640

Query: 1618 LVTAANRHANPRVTPRNFVQNLAFVVYRDPVIFMKAAQAVCQIEMVGDRPYVVLLXXXXX 1677
L + RH RV PR F+ +A V+ RDPV+FMKA + CQ+E G R +V+L
Sbjct: 1641 L--SGKRHIG-RVLPRTFLTTMAPVISRDPVVFMKAVASTCQLESSGGRDFVIL------ 1691

Query: 1678 XXXXXXXXXXXXXXXXTSGAATKMTSGDMALGSPVS-SQGKQTDLNTKNVKSNRKPPQSF 1736
SG + +L P+ S+ K D++ K KS+R+ P +F
Sbjct: 1692 --------SKEKEKPKVSG-----SEHGFSLNEPLGISENKLHDVSGKCSKSHRRVPANF 1738

Query: 1737 VTVIEYLLDLVMSFIPPPRAEDRPDGESSTASSTDMDIDS-SAKGKGKAVAVTPEES--- 1792
+ VI+ L+DLV+SF PR + + DGE++ S M++D + K KGK+ PE++
Sbjct: 1739 IQVIDQLIDLVLSF---PRVKRQEDGETNLIS---MEVDEPTTKVKGKSKVGEPEKASSS 1792

Query: 1793 ------KHAIQEATASLAKSAFVLKLLTDVLLTYASSIQVVLRHDADLSNARGPNRIGIS 1846
K I E + LA+ F+LKLL+D++L Y+ V+LR D ++S RG N S
Sbjct: 1793 RVGEPEKAEIPEKSEELARVTFILKLLSDIVLMYSHGTSVILRRDTEISQLRGSNLPDDS 1852

Query: 1847 --SGGVFSHILQHFLPHSTKQKKERKADGDWRYKLATRANQFLVASSIRSAEGRKRIFSE 1904
+GG+ H++ LP S ++ +W+ KL+ +A+ FLV RS EGRKRI +E
Sbjct: 1853 PGNGGLIYHVIHRLLPISLEK---FVGPEEWKEKLSEKASWFLVVLCSRSNEGRKRIINE 1909

Query: 1905 ICSIFVDFT----DSPAGCKPPILRMNAYVDLLNDILSARSPT------GSSLSAESAVT 1954
+ + F S P R+ A+ +L+ IL+ S + G S + A +
Sbjct: 1910 LSRVLSVFASLGRSSSKSVLLPDKRVLAFANLVYSILTKNSSSSSSNFPGCGCSPDVAKS 1969

Query: 1955 FVEVGLVQYLSKTLQVIDLDHPDSAKIVTAIVKALEVVTKEHVHSADLNAKGENSSKVVS 2014
++ G +Q L+ L VIDLDHPD+ K+VT I+K+LE +T+ NA + S+V +
Sbjct: 1970 MMDGGTIQCLTSILHVIDLDHPDAPKLVTLILKSLETLTRAA------NAAEQLKSEVPN 2023

Query: 2015 DQSNLD 2020
++ N D
Sbjct: 2024 EKKNRD 2029

Query: CNT0025457
Subject: sp|O13834|PTR1_SCHPO E3 ubiquitin-protein ligase ptr1

OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A /
CBS 708.71 / DSM 1257 / FGSC 987) GN=B11B22.010 PE=3 SV=4

 Score =  539 bits (1389), Expect = e-152,   Method: Compositional matrix adjust.
Identities = 378/1176 (32%), Positives = 567/1176 (48%), Gaps = 175/1176 (14%)

Query: 2540 IDPTFLEALPEDLRAEVL----SSRQNQVTQTSNEQPQNDGDIDPEFLAALPPDIREEVX 2595
ID +LEALPE+ R EV+ S+R++Q + +++ +N ++ EFL ALP ++R E+
Sbjct: 2976 IDAEYLEALPEEFRDEVIAQAISTRRSQAREQVSQEGENT-EVFQEFLEALPEELRNEIL 3034

Query: 2596 XXXXXXXXXXSQE--LEGQ---PVEMDAVSIIATFPSEIREEVXXXXXXXXXXXXXXXXX 2650
++ GQ P +MD SI+ TFP +R++V
Sbjct: 3035 HQEQHEQRRRERQNAAGGQDLGPADMDPASILLTFPPGLRQQVLLDQGEDIMEHLGPELA 3094

Query: 2651 XXXNML--RERFAHRYHSGSLFGMNXXXXXXXXXXXXXXXXXXLDRNAGDSSRQPTSKPI 2708
L R R H G + AG + Q K
Sbjct: 3095 AEARTLVARHRQLHAQQGGQAASRSRDAQRPT--------------EAGAGTVQKIQKRT 3140

Query: 2709 ETEGSPLVDKDALKALIRLLRVVQP-LYKGQLQRLLLNLCAHRESR----KSLVQILVD- 2762
+ ++DK + L+RL+ V Q + L + NLC +R++R SL+QIL D
Sbjct: 3141 VVQ---MLDKQGIATLLRLMFVSQQGSIRSSLFSIFANLCENRQNRLDVISSLLQILQDG 3197

Query: 2763 ----------MLMLDLQGSSKKSIDATEP-PFR---LYGCHANITYSRPQSTDGVPPLVS 2808
+ + K DA P P + G + N + P S++ P L+
Sbjct: 3198 CANMDAVERSFAQISHKAKQLKEKDAKTPHPLKRSLTGGTNNNGQF--PASSEVSPLLIV 3255

Query: 2809 RRVLETLTYLARNHPNVAKLLLFLEFPCPPTCHAETSDQRRGKAVLMEGDSEQNAYAXXX 2868
++ L+ L L++ +P++ + L T S R+GK + G +++ +A
Sbjct: 3256 QQCLDLLVELSKLNPHIPSVFLTEHETVASTLKRSLS--RKGKGKDVNGKAQK--FAINS 3311

Query: 2869 XXXXXXXXXYMRSVAHLEQLLNLLEVVMLN------------------------------ 2898
M S A ++ L +LL V +
Sbjct: 3312 LLTLLDRSLVMESSAVMQVLADLLNKVTIPLQAIERRRKEAEEQAKKKKEAEEKAATERE 3371

Query: 2899 -----------------AENEITQAKLEAASEKPSGPENATQDAQEXXXXXXXXXXXXXX 2941
A+ E TQ E+ SG + A QD +
Sbjct: 3372 AANAPEEQASTSTEQTPAQQEATQQPSESTPAAASGQQPAQQDQENKELEAP-------- 3423

Query: 2942 EDSSKLPPVDGESSLQKVLQ----SLPQAELRLLCSLLAHDGLSDNAYLLVAEVLKKIVA 2997
K D +S +K+ Q ++P+ L+L+ ++ S + +K +
Sbjct: 3424 --KEKADEKDVQSDEKKIRQLTPPTIPEHNLKLVINIFVARECSSKTFQNTISTIKNLSN 3481

Query: 2998 LAPFFCCHFINELAHSMQNLTLCAMKEL-----HLYEDSEK--------ALLSTSSANGT 3044
+ P F +EL + L+ + +L H+ + A S ++
Sbjct: 3482 I-PGAKKVFGDELVRQARVLSENILSDLDNLLPHILKAESGTQIQGVALAKFSPGASEQN 3540

Query: 3045 AILRVVQALSSLVTTLQEKKDPDHPAEKDHSDALSQISEINTALDALWLELSNCISKIES 3104
+LRV+ AL L + +K+D E D L + N +W +LS C+S I
Sbjct: 3541 KLLRVLTALDHLFDSKSKKQDKPAEGENTKEDLLGSLY-WNPTFGKMWDKLSACLSAIRQ 3599

Query: 3105 SSEYXXXXXXXXXXXXXXXXGVAPPLPAGTQNILPYIESFFVTCEKLRPGQPDAIQEAST 3164
+LP IES V C+ A+ A++
Sbjct: 3600 RDNMLNVATI----------------------LLPLIESLMVVCKNTTLSDASAVSNANS 3637

Query: 3165 SDMEDAXXXXXXXXXXXXHANLDEKHNAFVKFSEKHRRLLNAFIRQNPGLLEKSFSLMLK 3224
D F F+E+HRR+LN +R NP L+ +FSL++K
Sbjct: 3638 Q----------KEMLLTSPPPEDRIAGLFFTFTEEHRRILNELVRHNPKLMSGTFSLLVK 3687

Query: 3225 IPRLIEFDNKRAYFRSKI--KHQHDHH-HSPVRISVRRAYILEDSYNQLRMRSPQDLK-G 3280
P+++EFDNKR YF + K+Q H P+++ VRR ++ DS+ L + +LK G
Sbjct: 3688 NPKVLEFDNKRNYFNRSVHSKYQQTRHSFPPLQLQVRREHVFHDSFRSLYYKKADELKFG 3747

Query: 3281 RLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGND-LTFQPNPNSVYQTEHL 3339
+L + FQGEEG+DAGG+TREW+Q+LSR +FD +LF V +D TF PN S EHL
Sbjct: 3748 KLNIRFQGEEGVDAGGVTREWFQVLSRQMFDPNYVLFVPVSSDRTTFHPNKLSPINDEHL 3807

Query: 3340 SYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPAYYKNLKWMLEND 3399
+FKF+GR++GKAL++G+LL+ +F+R+ YK ILG V+ D+E+ DP YYK+L WMLEND
Sbjct: 3808 PFFKFIGRIIGKALYEGRLLECYFSRAVYKRILGKPVSVKDMESFDPDYYKSLVWMLEND 3867

Query: 3400 ISDVLDLSFSMDADEEKRILYEKAEVTDYELIPGGRNIKVTEENKHEYVNRVAEHRLTTA 3459
I+D++ +FS++ D ++ + +V D LI GRNI VTEENKHEYV + EH+L T+
Sbjct: 3868 ITDIITETFSVEDD-----VFGEVKVVD--LIENGRNIPVTEENKHEYVRLIVEHKLITS 3920

Query: 3460 IRPQITSFMEGFNELIPEELISIFNDKELELLISGLPDIDLDDLKANTEYSGYSIASPVI 3519
++ Q+ +F+ GF+E+IPEELI+IFN++ELELLISGLPDID+DD KANTEY YS +P I
Sbjct: 3921 VKDQMKAFLTGFHEIIPEELIAIFNEQELELLISGLPDIDIDDWKANTEYHNYSAGAPQI 3980

Query: 3520 QWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSA 3579
QWFW V+ F KE+ A+ LQFVTGTSKVPL GF L+G++G RF IH+ YGS + LPS+
Sbjct: 3981 QWFWRAVRSFDKEELAKLLQFVTGTSKVPLNGFKELEGMNGVSRFNIHRDYGSKDRLPSS 4040

Query: 3580 HTCFNQLDLPEYTSKEQLQERLLLAIHEANEGFGFG 3615
HTCFNQLDLPEY + E L+ +LL AI ++ FGF
Sbjct: 4041 HTCFNQLDLPEYENYETLRSQLLKAITAGSDYFGFA 4076



Score = 53.5 bits (127), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 50/227 (22%), Positives = 92/227 (40%), Gaps = 28/227 (12%)

Query: 1462 VPNWVPSCFLSIDRMLQLDPKLPDVTELDVLKKDNSNTQTSVVIXXXXXXXXXXXXXTGX 1521
+P W+P L + ML D + PD+ +K+D+ ++ + +
Sbjct: 1769 LPPWIPYILLIFEIMLFKDAQPPDIKWKQPVKEDDPIEESVIEVKEPNFLAEHRSSLLTT 1828

Query: 1522 XXXXXXXXXXXICCKCIQKQLPSATMHAILQLCATLTKLHAAAICFLESGGLHALLSLPT 1581
I K+ A ++L++ LT+ HA A E L L +
Sbjct: 1829 LLD---------FLPRIGKEESLAV--SVLRILVVLTRDHAVAKIVGEKKNLQRLFVMAK 1877

Query: 1582 SSLFSGFNSVAST--------IIRHILEDPHTLQQAMELEIRHSLVTAANRHANPRVTPR 1633
+G + T I+RHI+ED TL+Q E +IRH + + A P + P+
Sbjct: 1878 QLCGAGSTRLKQTHISEHIRQILRHIIEDEETLRQIFETDIRHLMTSRQRPSAAPGLEPQ 1937

Query: 1634 NFVQNLAFVVYRDPVIFMKAAQAVCQ----IEMVGD-----RPYVVL 1671
+++ A + R P F++ + + + + +GD P++VL
Sbjct: 1938 AYLRTQAHLALRSPKTFVEVSTELLKLNRAVSHLGDGTLRSTPFLVL 1984

Query: CNT0025457
Subject: sp|Q756G2|TOM1_ASHGO Probable E3 ubiquitin-protein ligase TOM1

OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
GN=ptr1 PE=1 SV=1

 Score =  476 bits (1225), Expect = e-133,   Method: Compositional matrix adjust.
Identities = 245/583 (42%), Positives = 360/583 (61%), Gaps = 62/583 (10%)

Query: 3039 SSANGTAILRVVQALSSLVTTLQEKKDPDHPAEKDHSDA-LSQISEI--NTALDALWLEL 3095
+S+N +LR ++AL + E++ P ++ S + Q+ E N +LW L
Sbjct: 2701 ASSNQAKLLRCLKALDYIF----ERR----PKGQEQSPGNIIQLLEFYDNLKFSSLWEVL 2752

Query: 3096 SNCISKIESSSEYXXXXXXXXXXXXXXXXGVAPPLPAGTQNILPYIESFFVTCEKLRPGQ 3155
S C+S + + + + +LP IES V C +
Sbjct: 2753 SECLSALRDHTS----------------------ITHVSTVLLPLIESLMVICRLVFIEL 2790

Query: 3156 PDAIQEASTSDMEDAXXXXXXXXXXXXHANLDEKHNAFVKFSEKHRRLLNAFIRQNPGLL 3215
P+ + + + +E F+ F+E+HR+++N + P L+
Sbjct: 2791 PEDVGKHISPILE-------------------RFKTLFISFTEEHRKIINMMVFTTPSLM 2831

Query: 3216 EKSFSLMLKIPRLIEFDNKRAYFRSKIKHQH-DHHHSPVRISVRRAYILEDSYNQLRMRS 3274
SFSL++K P+++EF+NKR YF ++ + + P+ I+VRR ++ DSY L +
Sbjct: 2832 SGSFSLLVKNPKVLEFENKRNYFNRQLHEEAAKEQYPPLNITVRRDHVFLDSYRALHFKD 2891

Query: 3275 PQDLK-GRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTV-GNDLTFQPNPNS 3332
++K +L +HF+ EEG+DAGG+TREW Q+L+R +F+ LF V G+ TF PN +S
Sbjct: 2892 ADEVKFSKLNIHFRDEEGVDAGGVTREWLQVLARQMFNPDYALFLPVTGDATTFHPNRDS 2951

Query: 3333 VYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPAYYKNL 3392
+HLS+FKF GR++GKAL+DG+LLD HF+R+ YKH+L V+ DIE++DP YYK+L
Sbjct: 2952 SVNPDHLSFFKFTGRIIGKALYDGRLLDCHFSRAVYKHMLHRSVSVKDIESLDPDYYKSL 3011

Query: 3393 KWMLENDISDVLDLSFSMDADEEKRILYEKAEVTDYELIPGGRNIKVTEENKHEYVNRVA 3452
WML NDI+D++ F++ EK + EK V +LIP GRNI VTE NK YVNR+
Sbjct: 3012 VWMLNNDITDIITEEFAV----EKDVFGEKTVV---DLIPNGRNIPVTELNKQNYVNRMV 3064

Query: 3453 EHRLTTAIRPQITSFMEGFNELIPEELISIFNDKELELLISGLPDIDLDDLKANTEYSGY 3512
+++L +++ Q+ S ++GF+++IP LI IFN++ELELLISGLP+ID+DD K NTEY GY
Sbjct: 3065 DYKLRESVKDQLKSLLDGFSDIIPSHLIQIFNEQELELLISGLPEIDIDDWKNNTEYHGY 3124

Query: 3513 SIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGS 3572
+++SP +QWFW V+ F +E++A+ LQF TGTSKVPL GF L+G+SG QRF IHK+YGS
Sbjct: 3125 NVSSPQVQWFWRAVRSFDEEERAKLLQFATGTSKVPLNGFKELEGMSGFQRFNIHKSYGS 3184

Query: 3573 TNHLPSAHTCFNQLDLPEYTSKEQLQERLLLAIHEANEGFGFG 3615
N LP +HTCFNQLDLPEY + EQL+ LL AI+E +EGFGF
Sbjct: 3185 LNRLPQSHTCFNQLDLPEYDTYEQLRSMLLTAINEGSEGFGFA 3227



Score = 85.9 bits (211), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 65/253 (25%), Positives = 122/253 (48%), Gaps = 6/253 (2%)

Query: 469 PSHMHLVCLAVKTLQKLMEYSSPAVSLFKDLGGVELLSQRLHVEVQRVIGVDSHNSMVTS 528
P ++V ++ L L++ S A F + G+++L R+ E++ G+ S +
Sbjct: 423 PQATYVVARSIVMLDHLIDGYSMAFPDFSESKGLDMLVDRVQYELEA--GLQDIKSGKGN 480

Query: 529 DALKSEEDHLYSQKR--LIKALLKALGSATYSPANPARSQSSNDNSLPISLSLIFQNVDK 586
+ D+ S R L+K LLK + S + ++ D+SL SL+ + ++ +
Sbjct: 481 PEIVLNMDYAISYDRYFLLKNLLKFVLHLIQSGGSVVELRNLIDSSLISSLAFLLEHHEV 540

Query: 587 FGGDIYFSAVTVMSEIIHKDPTCFPSLKELGLPDAFLSSVSAGVIPSCKALICVPNGLGA 646
+G +++ S +MS IH +PTC+ + E L AFL +V+ ++ S A+ +P GA
Sbjct: 541 YGSNLFASTTNIMSTFIHNEPTCYGIIHEKKLSHAFLDAVNRKILNSSDAITSIPLAFGA 600

Query: 647 ICLNNQGLEAVRETSALRFLVDTFTSRKYLIPM--NEGXXXXXXXXXXXXRHVQSLRSTG 704
ICLN+QG + E + + L FTS + + ++ RH SL+
Sbjct: 601 ICLNSQGFDLFLEKNPIPQLFSIFTSLNHCKSLISSDNAAILGTYIDELMRHQPSLKDPI 660

Query: 705 VDIIIEIINKLSS 717
V +I + +++S+
Sbjct: 661 VKMIFKACDQVSA 673

Query: CNT0025457
Subject: sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo

OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) GN=TOM1 PE=3 SV=2

 Score =  451 bits (1159), Expect = e-125,   Method: Compositional matrix adjust.
Identities = 232/534 (43%), Positives = 334/534 (62%), Gaps = 54/534 (10%)

Query: 3088 LDALWLELSNCISKIESSSEYXXXXXXXXXXXXXXXXGVAPPLPAGTQNILPYIESFFVT 3147
L +W+ LSNC+++ E P + +LP IES V
Sbjct: 2773 LGHIWVSLSNCLTRFEEK----------------------PRMSTSATILLPLIESLMVV 2810

Query: 3148 CE--KLRPGQPDAI--QEASTSDMEDAXXXXXXXXXXXXHANLDEKHNAFVKFSEKHRRL 3203
C+ K+R + DA+ EA D N F F++ H++L
Sbjct: 2811 CKHSKVRETK-DALLKYEAKKCDFARTPV-----------------ENLFFAFTDLHKKL 2852

Query: 3204 LNAFIRQNPGLLEKSFSLMLKIPRLIEFDNKRAYFRSKIKHQHDHHHSPVRISVRRAYIL 3263
LN IR NP L+ FSL++K P++++FDNKR YF ++++ H + ISVRR ++
Sbjct: 2853 LNEMIRSNPKLMSGPFSLLVKNPKILDFDNKRYYFTAQLR-AITHDRPKLSISVRREHVF 2911

Query: 3264 EDSYNQLRMRSPQDLK-GRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGN 3322
DSY L +S +D+K +L + F+GE G+DAGG+TREWYQ+LSR +F+ LF V +
Sbjct: 2912 LDSYRSLFFKSNEDIKISKLEISFKGEAGVDAGGITREWYQVLSRQMFNPDYALFIPVAS 2971

Query: 3323 D-LTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDI 3381
D TF+PN S EHLS+FKF+G ++GKA+ D LD HF+R YK+ILG V D+
Sbjct: 2972 DKTTFRPNRTSGINPEHLSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGKPVALKDM 3031

Query: 3382 EAIDPAYYKNLKWMLENDISDVLDLSFSMDADEEKRILYEKAEVTDYELIPGGRNIKVTE 3441
E++D YYK+L W+LENDI+D+++ +FS++ D+ Y + +V ELI G ++ VTE
Sbjct: 3032 ESLDLDYYKSLIWILENDITDIIEETFSVETDD-----YGEHKVI--ELIENGAHVAVTE 3084

Query: 3442 ENKHEYVNRVAEHRLTTAIRPQITSFMEGFNELIPEELISIFNDKELELLISGLPDIDLD 3501
+NKH+YV ++ E++L T+++ Q+ +F++GF +IP++LISIF+++ELELL+SGLPDID+D
Sbjct: 3085 QNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELLVSGLPDIDVD 3144

Query: 3502 DLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGP 3561
D K NT Y Y+ I +FW V+ F KE++A+ LQFVTGTSKVPL GF L G++G
Sbjct: 3145 DWKNNTIYVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGI 3204

Query: 3562 QRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKEQLQERLLLAIHEANEGFGFG 3615
+F IH+ YGS + LPS+HTCFNQLDLP Y S E L+ LLLAI+E +EGFG
Sbjct: 3205 SKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFGIA 3258



Score = 52.8 bits (125), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 29/97 (29%), Positives = 51/97 (52%)

Query: 570 DNSLPISLSLIFQNVDKFGGDIYFSAVTVMSEIIHKDPTCFPSLKELGLPDAFLSSVSAG 629
D+ + ++ + I +N FG + A+ V+ II+ +PT + L E G L +
Sbjct: 536 DSPILLAFNKILENRPVFGYTLVSHALDVVQTIINTEPTIYQVLVESGTIPYILQNFDQF 595

Query: 630 VIPSCKALICVPNGLGAICLNNQGLEAVRETSALRFL 666
+ P+ L +P + AICLN GL+ V+E + L++L
Sbjct: 596 LGPTSDLLCMLPEVISAICLNTDGLKQVKEKNLLKYL 632