Score =  704 bits (1818), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 548/2050 (26%), Positives = 968/2050 (47%), Gaps = 225/2050 (10%)

Query: 1265 LRSKNIEQQVGTVTALNFCLALRPPLLKLSPELVN---FLQEALQIAEADETVWVTKMMN 1321
            LR +    Q+G +    FC  L+P L  +   +V    F  E L + EA+++  +TK+  
Sbjct: 15   LRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDSA-LTKLPC 73

Query: 1322 AKIIMTWNKLRTACIELLCTAMAWGDLKAPNHSDLRAKIISMFFKSLTCRTTEIVNVAKE 1381
             K + +   LR     +            P     R KII+  FK+L    +E+    + 
Sbjct: 74   YKSLPSLVPLR-----IAALNALAACNYLPQS---REKIIAALFKALNSTNSELQEAGEA 125

Query: 1382 GLRQVVQQQRMPKDLLQSSLRPILVNLAHTRSLTMPXXXXXXXXXXXXSNWFNVTLGAKL 1441
             +R+ ++   +  D + + +RP+L+ L   RSLT+              N FN     ++
Sbjct: 126  CMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQM 185

Query: 1442 LDHLKKWLEPEKLAQSQKSWKAGDEPKIAAAMIELFHLLPPAASKFLDDLVTLVIDLERA 1501
            + HL+KW+E   +         G+E KI +A+I LFHL+P A    +   + +V++ ERA
Sbjct: 186  MQHLRKWMEVVVITHKGGQRSDGNEMKICSAIINLFHLIPAAPQTLVKPPLEVVMETERA 245

Query: 1502 LPEDQFYSEINSPYRAPLAKFLNRYAVEAVDYFL--ARLSHPKYFRRFM-YIICSDTGEL 1558
            +       E  SP+R PL KFL R+  + V+ F+  A L+ P++ R FM ++   D   L
Sbjct: 246  M-----LIEAGSPFREPLIKFLTRHPSQTVELFMMGATLNDPQWSRMFMSFLKHKDARPL 300

Query: 1559 RDQLAKSPQKILASAFSQFYSQTEAAGNQSSSVKDEGLTGAITEGFTGQSSSNMATGSDS 1618
            RD LA +P +        F +     G Q+          A+  G    S+SNM    D 
Sbjct: 301  RDVLAANPNR--------FITLLLPGGAQT----------AVRPG--SSSTSNMRL--DL 338

Query: 1619 YFNGLELISTLVKLMPEWLCNNRVVFDTLLLAWKSPSRIDRLQNEQELSLPQVMESKRLI 1678
             F  +++IS +VK    WL +   +   L   W S +  +R + E  ++     E K L 
Sbjct: 339  QFQAIKIISIIVKNDDAWLASQHSLVSQLRRVWVSETFQERHRKEN-MAATNWKEPKLLA 397

Query: 1679 KCFLNYLRHDRTEVGALFDMLSIFLYRSRIDYSFLKEFYVIEVAEGYAPNLKKIILNHFL 1738
             C LNY + +  ++  LF +L  F  R   + +FLKE+   E+ + Y+   K+ +   F+
Sbjct: 398  FCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFV 457

Query: 1739 NIFQSKHYGQDHLVVAMQILILPMLAHSFQNGQSWEVVDP---------SIIKTIVDKLL 1789
              F   ++G +     +Q ++ P   +SF+ G+  +++ P         SI    + K+L
Sbjct: 458  E-FNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVL 516

Query: 1790 DPPEEVSA---------EYDEPXXXXXXXXXXXXXXXXQSDLVHHRKELIKFGWNHLKRE 1840
            DP ++            +Y                    S L    + L+ F W  L  +
Sbjct: 517  DPEKQADMLDSLRIYLLQYATLLVEHAPHHIHDNNKNRNSKL----RRLMTFAWPCLLSK 572

Query: 1841 ---DNSSKQWAFVNVCHFLEAYQAPEKIILQVFIALLRTCQPENKLLVKQALDILMPALP 1897
               D + +    + + H +  +   +KI+LQVF +LL+    E + +V+QA+ IL PA+P
Sbjct: 573  ACVDPACRYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVP 632

Query: 1898 RRLPPGDSRMPIWIRYTKKILVEEGHSIPNMIHIFQLIVRHADLFYSCRAHFVPQMVNSL 1957
             R+  G   +  W   T+KI+VEEGH++P ++HI   IV+H  ++Y  R H V  MV+++
Sbjct: 633  ARMEDGHQMLTHW---TRKIIVEEGHTVPQLVHILHPIVQHFKVYYPVRHHLVQHMVSAM 689

Query: 1958 SRLGLPYNTTAENRRLAIELAGLVVAWERQRQSEMKVVQESENTSQIGDMLSPVIGGDPK 2017
             RLG   + T E RRLA++L+ +V+ WE QR  + +   + +  S  G+ ++ V     K
Sbjct: 690  QRLGFTPSVTIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSS-GEGVNSV---SIK 745

Query: 2018 RSSDVPTFGDDLSKRVKVEPGLQPLCVMSPGGASIPNIETPGSSGQPDEEYKP-NAAMEE 2076
            R   V +  +   KR +   G   +  +     S+P  ++  +        KP +    +
Sbjct: 746  RGLSVDSAQE--VKRFRAATG--AISAVFGRSQSLPGADSLLA--------KPIDKQHTD 793

Query: 2077 MIITFLIRVSLVIEPKDKESSS----MYKQALDLLTQAL--EVWPNANVKFNYLEKLLGN 2130
             ++ FLIRV+  +      + S    + ++ ++LL  AL  ++W  + +K  + +KLL  
Sbjct: 794  TVVNFLIRVACQVNDNTNTAGSPGEVLSRRCVNLLKTALRPDMWCKSELKLQWFDKLLMT 853

Query: 2131 L-TPSQSKDPATALAQGLDVMNKVLEKQPRLFIRNNINHISQILEPCFNNKMLDAGKSLC 2189
            +  P+Q       +  GL+V+N +L       I ++   + + +  C         +++ 
Sbjct: 854  VEQPNQVN--YGNICTGLEVLNFLLTVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVH 911

Query: 2190 SLLKMVFSAFPLEAATTP-----QDIKLLYQRVQDLIQKHLAAVTTPQISLEPSNANSII 2244
            SLL  + S FP E +T+      ++++ LY  V  +I + L          + ++AN   
Sbjct: 912  SLLSRLMSIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYE------KATSANPSQ 965

Query: 2245 SFALFVLNALAEVQK-NFIDPFIGLLLRVLQRLARDMGSSAGNHVRQGQRPEQDSSVNSR 2303
             F   +++  A     ++ID  I + +R LQ++ R+       H+   Q     +   + 
Sbjct: 966  LFGTLMIHKSACCNNPSYIDRLISVFMRSLQKMVRE-------HL-NPQTASGSTEATAA 1017

Query: 2304 PTVDPMVISNMKTVLKLISERV-MASSEFRRSMGQTLQALLSEKGTDPSVLLCILDMIKA 2362
             T + +++S     L L+  R+ + S E R++  QT+   L EK  D  +L  ++ +++ 
Sbjct: 1018 GTSELVMLS-----LDLVKTRLAVMSMEMRKNFIQTILTSLIEKSPDAKILRAVVKIVEE 1072

Query: 2363 WIEDDYRLASSTGSVSSLNPKEIIAYLQKLSVVDRKSFPPSVQEEWDAKYLQLLYSLCGD 2422
            W++++  +A++     +L  K I+  L K+     K FP  +  E +A++L L+  +  D
Sbjct: 1073 WVKNNSPMAAN--QTPTLREKSIL--LVKMMTYIEKRFPEDL--ELNAQFLDLVNYVYRD 1126

Query: 2423 TAKYQMALRQEYFHKVERQYMLGLRAKDPEMRKRFFKLYHDYVGKTLFARLQFIIQTQDW 2482
             A        E   K+E  ++ GLR   P +R +FF+++ + + + ++ RL ++  +Q+W
Sbjct: 1127 EALSG----SELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNW 1182

Query: 2483 EAVSDVFWLKQGLDLILAILVENEPITLAANSARVPALMTSGPVSDR--------MIMPQ 2534
            EA+   FW+KQ ++L+LA+  ++  I  +   A +P++     ++D         +   +
Sbjct: 1183 EAMGSHFWIKQCIELLLAVCEKSTAIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVK 1242

Query: 2535 QAPDAQESL----------------DGTSL-------------SFDSLTTRHAQFLNEAS 2565
            Q P  +E+                 D TS                  LT RH +FL+   
Sbjct: 1243 QEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDTLR 1302

Query: 2566 KLVVADVMAPLRELAFADPNVAYHLWVLVFPIVWVTLHKEEQVALAKPIIALLSKDYHKR 2625
            ++    +++   +L      +A   WV +FP +W  L   +Q ALA  I   L    H+ 
Sbjct: 1303 EVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCSGSHQV 1362

Query: 2626 QQGCRPNVAQALLEGLHLSHPQPRMPSELIKYIGKTCNAWHTSIALLESHMMHMN----- 2680
            Q+ C+P+     +E +    P   M   ++KY+GKT N W  S  +LE            
Sbjct: 1363 QRDCQPSALNCFVEAMSQCVPPIPMRPCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLPI 1422

Query: 2681 -----------------EAKCSESLAELYRLLNEDDMRYGLWKRRSITAETRAGLSLVQH 2723
                             + +  +SLAELY LL E+DM  GLW++R   +ET   ++  QH
Sbjct: 1423 KPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKFSETATAIAYEQH 1482

Query: 2724 GYWQQAQNLFYQAMIKATQGTYNNTVPKA---EMCLWEEQWLSCATQLGQWEVLADFG-- 2778
            G+++QAQ  + +AM KA +    +    A   E  LWE+ W+ C+ +L QWE L +FG  
Sbjct: 1483 GFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALTEFGQS 1542

Query: 2779 KGVENYEILLDCLWKAPDWTYMKENVI------PKAQVEETPKLRLIQSFFTLHDKGTNG 2832
            KG  N  ++L+C W+  +WT MKE ++      PK   E   K+ + + +  +       
Sbjct: 1543 KGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPK---EMAWKVNMYRGYLAICHPEEQQ 1599

Query: 2833 VGEAENLVSKGVELALEQWWQLPEMSVQSRMPLLQQFQQLVEVKESSKILLDIANGNKPX 2892
            +   E LV     LA+ +W +LP +      PLLQ  QQ++E++E+++I   +   N   
Sbjct: 1600 LSFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTN--- 1656

Query: 2893 XXXXXXXXXXXXXFADLKDILETWRLRTPNEWDNMTVWYDLLQWRNEMYNSVIDAFKDFG 2952
                           D+K +++TWR R P   D+++ W  +  WR   Y +++ A+++  
Sbjct: 1657 -------LGRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSVFMWRQHHYQAIVTAYENSS 1709

Query: 2953 QTNPQLHH--LGYRDKAWNVNKLAHIARKQGLPDVCVTILDKMYGHATMEVQEAFVKICE 3010
              +P  ++  LG    A  + +   IARKQGL +V + IL +++   T+ + + F KI +
Sbjct: 1710 HHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQ 1769

Query: 3011 QAKAYLEMKG-----ELVSGLNLINNTNLEFFPVKNKAEIFRLRGDFLLKMNDCENANVA 3065
            Q K YL++ G     E + GL +I +TNL++F  +  AE + L+G FL ++N  E AN A
Sbjct: 1770 QVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKA 1829

Query: 3066 YSNAITLFKHLPKAWISWGNYCDMVFKETKDEIWLEYAVSCFFQGIKY-GVSNSRSHLAR 3124
            +S A+ +   L KAW  WG+Y + +F + +       A++C+    ++   S SR +LA+
Sbjct: 1830 FSAAVQMHDVLVKAWAMWGDYLESIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAK 1889

Query: 3125 ILYLLSFDTQNEPAGRALDKYLEQLPHWVWLSWIPQLLLSLQRSEAQHCKLVLLKIAQVY 3184
            +L+LLSFD        A+DKY   +P   WL+WIPQLL  L  SE +    ++ ++ +VY
Sbjct: 1890 VLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVY 1949

Query: 3185 PQALYYWLRT 3194
            PQA+Y+ +RT
Sbjct: 1950 PQAVYFPIRT 1959



 Score =  209 bits (531), Expect = 4e-52,   Method: Compositional matrix adjust.
 Identities = 142/473 (30%), Positives = 241/473 (50%), Gaps = 39/473 (8%)

Query: 3410 KEYKQDFERDLDPESATTFPAT--LAELTERLKHWKNVLQSNVEDRFPAILKLEEESKIL 3467
            ++ K  F  D D     + P +  L  L  +LK W  +L++  + + P    +EE+ + L
Sbjct: 2120 QKLKGQFTTDFD----FSVPGSMKLHNLISKLKKWIKILEAKTK-QLPKFFLIEEKCRFL 2174

Query: 3468 RDF--HVVDIELPGQYFTDQEVAPDHT-VKLDRVGPDIPIVRRHGSSFRRLTLIGSDGSQ 3524
             +F     ++E+PG++   +   P H  +K+ R  P + IV++H ++ RRL + G +G  
Sbjct: 2175 SNFSAQTAEVEIPGEFLMPK---PTHYYIKIARFMPRVEIVQKHNTAARRLHIRGHNGKI 2231

Query: 3525 RHFIVQT-SLTPNARSDERMLQLFRVLNKMFDKHKESRQRHLAIHTPIIIPVWSQVRMVE 3583
              ++V   +    +R +ER+LQL R+LN   +K KE+ +RHL    P ++ V  Q+R+VE
Sbjct: 2232 YPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVE 2291

Query: 3584 DDLMYSTFLEVYEINCARHNREADSPITIFKEQLN--QAISGQVSPEAVVELRLQAYNEI 3641
            D+    + +E+Y+  CA+   E D+PI+ + ++L   QA   Q S + + ++      E+
Sbjct: 2292 DNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASHQVLRDI----LKEV 2347

Query: 3642 TKNIVNDNIFSQYMHKILPTGNHLWTFKKQFAIQVALSCFMSYMLQIGGRAPNKILFAKN 3701
              N+V  ++  ++     P     WTF+K F IQ+AL  F  ++L +    P  +  A++
Sbjct: 2348 QSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQD 2407

Query: 3702 TGKI----FQNDFHPAYDPNGMIEFNELVPFRLTRNMQAFFSNFGVEGLIVSAMCSAAQS 3757
            TGK+    F+ D +   D  G ++ N  VPFRLT N+  F +  GV G + ++M + A+ 
Sbjct: 2408 TGKLNVAYFRFDIN---DATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARC 2464

Query: 3758 VVSPKQSQHIWHHLAMFFRDELLSWSWRRPLGIPSVPVAAGMINPLDFQQKVINNVEHVI 3817
               P  +  +   L    RDE+++W  +      S   AAG    +D QQ +++ V+  +
Sbjct: 2465 FAQP--NFKVDGVLKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQ-LVSLVQKAV 2521

Query: 3818 TRIKLISPHYLADEEENSSEPPQSVQRGVTDLVEAALSSRNLCMMDPTWHPWF 3870
            T I +   H LA  +   S+        V  LV AA S  NLC MDP WHPW 
Sbjct: 2522 TAI-MTRLHNLAQFDGGESK--------VNTLVAAANSLDNLCRMDPAWHPWL 2565

 Score =  639 bits (1649), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 499/1857 (26%), Positives = 856/1857 (46%), Gaps = 229/1857 (12%)

Query: 2076 EMIITFLIRVSLVIEPKDKESSSMYKQALDLLTQALEV--WPNANVKFNYLEKLLGNLTP 2133
            E I+TFLI+  L + P+  E + + K+ L L         W +  +  N+ EK+L ++  
Sbjct: 2008 EAILTFLIKF-LSLFPEPVEENPLSKKGLSLFNDLFSFPRWKDCQLNSNFFEKILVDMDF 2066

Query: 2134 SQSKDPATALAQGLDVMNKVLEKQPRLFIRNNINHISQILEPCFNNKMLDAGKSLCSLLK 2193
            + +      +A  L V   +L+ +   +I+   +HI  +++       L    SL  ++ 
Sbjct: 2067 NDNN--YRTVANTLFVFGVILKNRGMEYIQREYSHIIALIDKSLRCGKLPVTHSLEQIIL 2124

Query: 2194 MVFSAFPLEA-----ATTPQDIKLLYQRVQDLIQKHLAAVTTPQISLEPSNANSIISFAL 2248
            ++  + P +A          D K   Q +  +I  +LAA T         N  S I +  
Sbjct: 2125 LLLQSHPTQAEEEEDTNEADDFK---QLLLSVIHDNLAAAT---------NIESAICYLQ 2172

Query: 2249 FVLNALAEVQKNFIDPFIGLLLRVLQRLARDMGSSAGNHVRQGQRPEQDSSVNSRPTVDP 2308
             V ++  E     + P    L +  Q++ARD      + V   Q   Q S   + P+   
Sbjct: 2173 IVKSSNPEALDGLLLP----LNKCFQKVARD------HIVACMQSAIQASGKVTLPSASD 2222

Query: 2309 MVISNMKTVLKLISERVMASSEFRRSMGQTLQALLSEKGTDPSVLLCILDMIKAWIEDDY 2368
             V   + + +++I  R+ +  + RR     +  LL EK +   +   IL++ K W+    
Sbjct: 2223 TVSKLLISFIEIIRVRMASLGDQRRWFLSVVVQLL-EKSSSFELCEHILNVTKEWV---- 2277

Query: 2369 RLASSTGSVSSLNPKEIIAYLQKLSVVDRKSFPPSVQEEWDAKYLQLLYSLCGDTAKYQM 2428
                     S L  KE  A L K+     ++F      +   +   LL ++  D     +
Sbjct: 2278 ----IVKRDSFLTVKEKTALLLKM-----RTFEGRFDNKLYIEACDLLSTIYRDP----I 2324

Query: 2429 ALRQEYFHKVERQYMLGLRAKDPEMRKRFFKLYHDYVGKTLFARLQFIIQTQDWEAVSDV 2488
                E   ++++ ++L   +KD ++R  F  ++   + + +++RL FI+    W+ +  +
Sbjct: 2325 FAHTELTARLKQAFLLATASKDTKIRMDFMDIFDSSMSRNVYSRLTFILDATSWDTIPSI 2384

Query: 2489 FWLKQGLDLILAILVENEPITLAANSARVPALMTSGPVSDRMIMPQQAPDAQESLDGTSL 2548
            +W+KQ   ++L  +   +P+ L  NS R   +  + P+   +      P+     +G+++
Sbjct: 2385 YWIKQANYILLGAINAKQPVRLTDNSLRFAPVPMTKPILSSL------PEVFSKHNGSAI 2438

Query: 2549 SFDSLT--TRHAQFLNEASKLVVADVMAPLRELAFADPNVAYHLWVLVFPIVWVTLHKEE 2606
                 T   +   FL    +L V  ++ PL  +       A  LW  +FP+ W  L  + 
Sbjct: 2439 PLGRFTFFKQLDLFLKRNKELTVQKIIFPLAHIQMLSDADANKLWQYIFPLAWKILSSDN 2498

Query: 2607 QVALAKPIIALLSKDYHKRQQGCRPNVAQALLEGLHLSHPQPRMPSELIKYIGKTCNAWH 2666
            +  L+K +I LL++DYH +Q   RPNV   L+        +  +P  L+KY+GK    +H
Sbjct: 2499 RSDLSKSLIYLLTRDYHIKQVNNRPNVISTLVSSFVKCAAKLELPPHLVKYLGKLYGVYH 2558

Query: 2667 TSIALLESHM-----MHMNEAKCSES----LAELYRLLNEDDMRYGLWKRRSITAETRAG 2717
             S++LLE  +     M+ N AK  ES    +AELY  LNEDDM YG W+R     +T+  
Sbjct: 2559 ESVSLLEIQLSDKYDMYQN-AKVQESRADAVAELYASLNEDDMFYGHWRRNCKYLQTQVA 2617

Query: 2718 LSLVQHGYWQQAQNLFYQAMIKATQGTYNNTVP--KAEMCLWEEQWLSCATQLGQWEVLA 2775
            LS  Q G W +AQ L+ QA  KA     +  +P  ++E  LWE+QW+ CA +L QW+VL 
Sbjct: 2618 LSYEQLGMWGRAQQLYEQAQTKAR----SEAIPFSESEYNLWEDQWVMCAQKLQQWDVLT 2673

Query: 2776 DFGKGVENYEILLDCLWKAPDWTYMKENV---IPKAQVEETPKLRLIQSFFTLHDKGTN- 2831
            +  K   + E+LL+C W+  DW+  +E++   I       TP+    Q F TL    +  
Sbjct: 2674 ELAKHEGSSELLLECAWRISDWSNNRESLEVAIKSLSDVPTPRKLTFQCFMTLQKSVSQP 2733

Query: 2832 -GVGEAENLVSKGVELALEQWWQLPEMSVQSRMPLLQQFQQLVEVKESSKI---LLDIAN 2887
              + E + ++S+ ++LAL +W QLPE   QS   LL  FQQ VE++E++ I   L  I  
Sbjct: 2734 LAIKEFQQVLSEAIQLALIKWHQLPEKVNQSHYSLLHLFQQFVELQEAATIYSHLNAINF 2793

Query: 2888 GNKPXXXXXXXXXXXXXXFADLKDILETWRLRTPNEWDNMTVWYDLLQWRNEMYNSV--- 2944
             N P                 +K  L+ W+ R PN WD++ +W DL+ WR  +++ +   
Sbjct: 2794 QNLPTNVQL------------IKSALQVWQERLPNVWDDINLWRDLISWRQIVFSMINRV 2841

Query: 2945 -------IDAFKDFGQTNP---QLHHLGYRDKAWNVNKLAHIARKQGLPDVCVTILDKMY 2994
                   I A      +NP        GY + AW +N+ AH+ARK  LP VC+  L K+Y
Sbjct: 2842 YLPLVPTIQANSSADSSNPPNTSFLFRGYHETAWLINRFAHVARKHKLPSVCLNQLTKIY 2901

Query: 2995 GHATMEVQEAFVKICEQAKAYLEMKGELVSGLNLINNTNLEFFPVKNKAEIFRLRGDFLL 3054
                +E+QEAF K+ EQ   YL+   +L +GL ++ NTNL +F  + K+E   L+G FL 
Sbjct: 2902 TLPNIEIQEAFYKLREQVLCYLQNPRDLKTGLEVVTNTNLMYFNSRQKSEFVTLKGKFLE 2961

Query: 3055 KMNDCENANVAYSNAITLFKHLPKAWISWGNYCDMVFKETKDEIWLEY-AVSCFFQGI-K 3112
            K+N  E AN  Y+ A+ +   LPKAW  WG Y D++F ++ D +     A+SC+ Q    
Sbjct: 2962 KLNRGEEANQMYAAAVQIDLGLPKAWAEWGRYNDLLFNKSPDNLSAACNAISCYLQAAGT 3021

Query: 3113 YGVSNSRSHLARILYLLSFDTQNEPAGRALDKYLEQLPHWVWLSWIPQLLLSLQRSEAQH 3172
            Y  S +R  LAR+L+LLS +       +A + Y   +P W WL++IPQLL SL + + + 
Sbjct: 3022 YQSSKARKMLARVLWLLSLNDSAGTIVKAFESYKGDIPVWHWLTFIPQLLNSLSKGDTKC 3081

Query: 3173 CKLVLLKIAQVYPQALYYWLRTYLMERRDVATKTEMGRIXXXXXXXXXXXXXXXXXXSEG 3232
              +VL KIA+ YPQAL++ LR                                       
Sbjct: 3082 APVVLKKIAKSYPQALFFTLR--------------------------------------- 3102

Query: 3233 NARTSNLGGGNMTSDNQVHQATQSGGAAVSHDGGNLQGQESDRSNVEGG-TSAGHDQGQP 3291
                        T+   + Q  ++  AA   +  +   +  D  +++    S       P
Sbjct: 3103 ------------TAREDIAQVKRTEMAAWKSNTTDENKRNEDILSIQSNFLSTNQSTNAP 3150

Query: 3292 SSTGADGSQMPARRNNGLGWVTSAASAFDAAKDIMEALRSKHTNLANELEVLLSEIGSRF 3351
            ++   DG                +   ++   +IM  L++ +  LA  +E L+ +I ++F
Sbjct: 3151 ATNKEDGL---------------SKKVWEYIDEIMSILKTAYPLLALTMETLVDQIQAKF 3195

Query: 3352 VTLPEERLLAVVNALLHRCYKYPTATTGEVPQSLKKELSGVCRACFSQDAVNKHVDFVKE 3411
                +     +V ALL+   ++ +   G V   +K  L     +  S  A N   D+ K+
Sbjct: 3196 KCKNDGDAFRLVVALLNDAVQH-SIRLGIVTDEMK--LPSSTESNLSLFADNILPDYCKQ 3252

Query: 3412 -YKQDFERDLDPESATTFPATLAELTERLKHWKNVLQSNVEDRFPAILKLEEESKILRDF 3470
             +K+DF  + +   +  F         +L+ W++  +  +  + P    LE+ S  L +F
Sbjct: 3253 LFKEDFIVNSNGLKSYIF---------KLRKWRSYFE-RLLSKVPKKQYLEQYSSFLCEF 3302

Query: 3471 H---VVDIELPGQYFTDQEVAPDHTVKLDRVGPDIPIVRRHGSSFRRLTLIGSDGSQRHF 3527
            H     +IE+PGQY   ++     +  ++R  P++ ++  HG  +RRL++  + G+   F
Sbjct: 3303 HHQKFDEIEVPGQYLLHKDNNNSFSC-IERFLPEVELIVGHGVCYRRLSIRSNGGTIHPF 3361

Query: 3528 IVQTSLTPNARSDERMLQLFRVLNKMFDKHKESRQRHLAIHTPIIIPVWSQVRMVEDDLM 3587
            ++Q     N+R +ER +QL R LN     + E+R+R L  + P +IP+ S +R++ED   
Sbjct: 3362 VIQYPSARNSRREERFMQLTRYLNDALALNCETRRRCLKFYIPAVIPLSSHIRLLEDQPS 3421

Query: 3588 YSTFLEVYEINCARHNREADSPITIFKEQLNQ---AISGQVSPEA-----------VVEL 3633
              T  ++YEI   R+N   D P  +F  +L++    ++ Q+S E+           +   
Sbjct: 3422 SITLQKIYEIYSERNNFSRDDPKELFTNELSKHMMELNSQISQESTDAEKLANRKQLFSR 3481

Query: 3634 RLQAYNEITKNIVNDNIFSQYMHKILPTGNHLWTFKKQFAIQVALSCFMSYMLQIGGRAP 3693
            R+  +  I K      I   Y   I    + LW F+K F+ Q A   F++Y+L I  R P
Sbjct: 3482 RIGMFENIQKLYSPSTILKDYFSSIFTNYSDLWLFRKNFSYQYACFSFITYILSINNRIP 3541

Query: 3694 NKILFAKNTGKIFQNDFHPAYDPNGMIEFN-ELVPFRLTRNMQAFFSNFGVEGLIVSAMC 3752
             K++F++++G ++  +  P+   +  +  N E+VPFR T N++ F      EGL+  ++ 
Sbjct: 3542 AKLVFSRDSGGVWTTEALPSMVSSTPVYHNGEIVPFRFTPNIKEFIGKTCTEGLLGPSIM 3601

Query: 3753 SAAQSVVSPKQSQHIWHHLAMFFRDELLSWSWRRPLGIPSVPVAAGMINPLDFQQKVINN 3812
            + A+++  P     ++  L +F RD+L  W  ++  G   VP    M+N      KV +N
Sbjct: 3602 AIARALSKPDFDLDMY--LGIFIRDDLFWWLAQQTKG---VPADFSMLN------KVNSN 3650

Query: 3813 VEHVITRIKLISPHYLADEEENSSEPPQSVQRGVTDLVEAALSSRNLCMMDPTWHPW 3869
             + ++ R+  +S     +           V +   D +  A SS+ L  MD  W PW
Sbjct: 3651 TDLIMRRVASLSQVAYGN---------LPVNQTAIDYLAQASSSKVLAQMDVLWAPW 3698



 Score =  320 bits (821), Expect = 7e-86,   Method: Compositional matrix adjust.
 Identities = 252/955 (26%), Positives = 457/955 (47%), Gaps = 70/955 (7%)

Query: 4   INSSNMEQHSQKLLEPDLPVQVRLQLAMEVRDSLEMTHTPDYLNFLRCYFRAFSAILSNF 63
           ++ S  E    +L +  L  + +   A+E+RD+L+     D L   +  F  F  +L + 
Sbjct: 39  MDVSQCEHWHNRLCDVGLDSKQKANTAIEIRDALD-----DVLVTEKTNFETFIPLLEDT 93

Query: 64  TAPQGTEN-------AEHKLRNVVIEILNRLPHSEVLRPFVQDLLKLSLRVLTQDNEDNA 116
            +    E        A H+LR  ++E+L +    +    FV     + LR++  DNE+ A
Sbjct: 94  LSLLEKERPVFSSLAATHRLRIALLELLKKSGSYKGFEAFVNRTFAVLLRIVVNDNEEMA 153

Query: 117 LLAIRIVFDLLRNFRPTVEAEVQPFLDFVVTIYRNFPNTVTHFFDNPNVSANIAAAVPNQ 176
           +LA+++V  L ++     +  VQ FL  VV  Y++    V+  F  P  + N  ++ P  
Sbjct: 154 VLALKLVVLLFKDHSSLAKGHVQEFLSIVVENYKSMTTVVSEAFP-PRSAPNTPSSHPMS 212

Query: 177 HLDPTADAPGTVAVPGGGQLNPSARSFKIVTESPLVVMFLFQLYAKLVQTNIPYLLPLMV 236
                + A   +   G   +  ++ SFK+  E P++V  LFQ Y  L+   +P L PL++
Sbjct: 213 AASSASPAEIGMEHAGPKMIPKASSSFKVTAEFPIIVFLLFQTYKDLIPKMLPLLAPLVL 272

Query: 237 SAISIKGPDK----------------VPPHLKTP--FVELKGAQVKTLSFLTYLLKSNAD 278
             IS++ P +                V P L+    + +L  AQ+K+ SFL YLL+S   
Sbjct: 273 QFISLRPPPQAEARRLAESQKEVFIGVVPSLRRNHLYNDLISAQIKSFSFLAYLLRSFGA 332

Query: 279 HIKSYEESICKSIVNLLVTCPPDSVSIRKELLVGLKQVLNTEYRRGLFPLIDTLLDERVL 338
            +K +E SI    + L + CP +    R+ELLV  + VL+T+Y RG  P +D LLD ++L
Sbjct: 333 ALKQFESSIPICTLQLFMDCPSELYQTRRELLVATRHVLSTDYLRGFLPYVDQLLDTKIL 392

Query: 339 IGTGRVCIETLRPLAYTLLAELVHYVRGDLSLPQLSRIIYLFSRNMHDSSLTLVIHTTSA 398
           +G+G     +LRP+A+++LA+++HYVR +LS  Q+ ++I L+   + D   T  I   + 
Sbjct: 393 VGSGITSQHSLRPMAFSMLADMLHYVRMELSPQQIYKVILLYFSILMDDFYTSAIQAMAT 452

Query: 399 RLMLNLVEPIY---EKGIDQPSMDEARILLGRILDAFVGKFRTLKRTIPQLLEEGEEGKE 455
           +L+LNLVE I    +    +  +    + L R L +   +F  L+ +    L+E  + K+
Sbjct: 453 KLILNLVERIVALEDFSTSRSLLFAILLCLLRKLTSLNFEFMKLRDS----LQENADLKQ 508

Query: 456 HQNLRMKLEVPL-QTVLNLQPPLEYTKEINDYKSLIRTLVLGMKTIIWSITHAHWPRPXX 514
            +    K ++P+ +       P    K + D   L +  +LG+K +++ +   + P    
Sbjct: 509 IKIEENKHDLPMFENPTGAAQPSGLDK-LKDCIFLFKNTLLGIKPVLFGLKQRNIPLANG 567

Query: 515 XXXXXXNLS------------------VQPFRGLREDEVRKTSGVLKSGVHCL-----AL 551
                   S                  V+  +G    +  + +GV KS  +       + 
Sbjct: 568 SIFTAQEWSEKLHLSSTNEVLLFRRLLVESLKGFSYYQTDEKTGVFKSSKNLAYSQLDSS 627

Query: 552 FKEKDEERDILQCFSQMLAIM----EARDIMDMFSFCMPDLFDCMITNNQLLHIFSSLLQ 607
                 +    +   +MLA +    +    +++     P++F+C++ N  LLHIF   + 
Sbjct: 628 LTTNPSKLLEEKELLEMLATLFLHLDPSVFVEILESEFPNIFECLVDNLALLHIFQFWMS 687

Query: 608 APKVLRPFTDVLINFLVSSKLDALKQPDSPAAKLVLQLFRFLFVAAAKAPESCERTLQPH 667
                   T ++++F   + L  +    S    ++L+LF+  F+     PE     L+PH
Sbjct: 688 NEVTSVNCTGIVLSFCCDN-LAKIGSGQSTRVSVLLRLFKLAFMTVNVFPEKNAEVLRPH 746

Query: 668 VPVIMEVCMKSATEVEKPLGYMHLLRSMFRALNIAKFDSLMRDLIPSLQPCLNMLLSMLD 727
           +  I+   ++  T+  +PL Y++L++++FR ++  KFDSL ++++P LQ  L     ++ 
Sbjct: 747 ISYIISTSLELTTDAVEPLNYVYLMKALFRNISGGKFDSLYKEILPLLQVMLECFNRLIF 806

Query: 728 GPTSEDMRDLILELCLILPARLSSLLPHIPRLMKPLVLALKGSDDLVSLALRTLEFWIDS 787
             TS   ++L  ELCL LP RLS LLPH+  LMKPL++ALKG  ++ S  LR  E  +D+
Sbjct: 807 TVTSTSQKELYAELCLTLPIRLSVLLPHMNFLMKPLIVALKGPPEIASQGLRIFELCLDN 866

Query: 788 LNPDFLEPSMANLMSDVILALWSH--LRPPPYTWGTKSLELLGKLGGRNRRFLKEPLALE 845
           L  +FL+P + ++M D+++ LW+H  L          ++ +LGK+GGRNR+        +
Sbjct: 867 LTQEFLDPLLDSIMPDLLICLWNHSRLNQSNNQLHQSAVRILGKMGGRNRQIYLGTFGFD 926

Query: 846 CKENPEHGLRLVLTFEPATPFLVPLDRCIHFAVSAVMQGNSMEAFYRKQALQFIR 900
             ++      +  +F+ ++            +  AV+   + +   +KQA Q ++
Sbjct: 927 FLQDENIFPSIQFSFQGSSQNFSLEHSKFLMSSCAVLNNQNSDLEEKKQAFQMVK 981



 Score =  149 bits (377), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 104/338 (30%), Positives = 168/338 (49%), Gaps = 11/338 (3%)

Query: 1215 VELFNPNTSIVVRKNVQACLSLLASRTGXXXXXXXXXXXXXXXXXXXXRSLRSKNIEQQV 1274
            +EL +PN    VR  VQ  +  +++ +                     + LR+     Q+
Sbjct: 1256 LELLHPNDH--VRNTVQQAIENISNNSKLSVVDLLLPIKDRLLSPIFGKPLRALPFTIQI 1313

Query: 1275 GTVTALNFCLALRPPLLKLSPELVNFLQEALQIAEADETVWVT--KMMNAKIIMTWNKLR 1332
            G + A+ +CL   P  L L+ EL    +E + +A+A++   VT  K   +K   +  KLR
Sbjct: 1314 GHIDAITYCLHRSPSFLDLTDELYRLFRETIALADAEDEALVTMLKTSQSKDSSSLRKLR 1373

Query: 1333 TACIELLCTAMAWGDLKAPNHSDLRAKIISMFFKSLTCRTTEIVNVAKEGLRQVV-QQQR 1391
              C+ LL  ++       P H+  R KII++FFK L     EI +VA + LR V+ Q Q+
Sbjct: 1374 ATCLHLLFASLVAHKFDQPQHAQTRTKIIAIFFKDLYSPHKEIYSVAIDALRHVLSQNQK 1433

Query: 1392 MPKDLLQSSLRPILVNLAHTRSLTMPXXXXXXXXXXXXSNWFNVTLGAKLLDHLKKWLEP 1451
            +PK+LLQS LRPIL+NL+    L++             +N+F V +G KLL HL    + 
Sbjct: 1434 LPKELLQSGLRPILMNLSDHNKLSVNGLEGLSRLLRLLTNYFKVEIGRKLLQHLNVLSDS 1493

Query: 1452 EKLAQSQKS-WKAGDEPKIAAAMIELFHLLPPAASKFLDDLVTLVIDLERALPEDQFYSE 1510
            + L  +  S  K     +I  +++ +F  LPP +++FL DL++ V+++E  L +   YS 
Sbjct: 1494 KVLETASLSLLKTNPRIEIIVSLVNVFRDLPPLSAQFLGDLLSSVVNIEAVLRK---YS- 1549

Query: 1511 INSPYRAPLAKFLNRYAVEAVDYFLARLSHPKYFRRFM 1548
             NSP R PL  F++ +A +   Y L    +     RF+
Sbjct: 1550 -NSPLRKPLYSFMDLHANDTWMYILNNARNGDLITRFV 1586



 Score =  119 bits (299), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 59/178 (33%), Positives = 103/178 (57%), Gaps = 8/178 (4%)

Query: 1825 HRKELIKFGWNHLKREDNSSKQWAFVNVCHFLEAYQAPEKIILQVFIALLRTCQPENKLL 1884
            +RK +I   WN++K ED   KQ A+  +  F+ AY  P KI+  V++++L+T QPE +  
Sbjct: 1827 YRKSVIMSAWNYIKLEDPMVKQAAYATIACFISAYDTPAKIVTPVYVSILKTYQPEVRAF 1886

Query: 1885 VKQALDILMPALPRRLP-PGDSRMPIWIRYTKKILVEEGHSIPNMIHIFQLIVRHADLFY 1943
            ++ +L  L+  L  RL  P DS  P+W +  + ++ E+   I   + ++Q I +  DLF+
Sbjct: 1887 IEFSLASLLSVLTARLSSPSDSTFPLWAKLPRLVISEDVQGISQPLTVYQFICKAPDLFF 1946

Query: 1944 SCRAHFVPQMVNSLSRLGLPYNTTAENRRLAIELAGLVVAWERQRQSEMKVVQESENT 2001
            SC +HF+  MVN+L +L    + + E R+LA+++    + W+R++        ESEN+
Sbjct: 1947 SCCSHFIVPMVNALPKLVSFSSASTEPRKLALDIVQTFINWQRKQ-------NESENS 1997

 Score =  580 bits (1495), Expect = e-165,   Method: Compositional matrix adjust.
 Identities = 472/1855 (25%), Positives = 845/1855 (45%), Gaps = 215/1855 (11%)

Query: 2078 IITFLIR-VSLVIEPKDKESSSMYKQALDLLTQALE--VWPNANVKFNYLEKLLGNLTPS 2134
            I+++L R V L  EP    +  +  +A+ LL + L    W +  +K ++  K + +   +
Sbjct: 1952 ILSYLFRFVCLFSEPF---TEGLCSEAISLLERLLSSGTWASLGMKLSFFTKSITHFDAT 2008

Query: 2135 QSKDPATALAQGLDVMNKVLEKQPRLFIRNNINHISQILEPCFNNKMLDAGKSLCSLLKM 2194
             +   +   A  L  ++ V+      +I  N++ +  +LE    N+ +    ++ + +  
Sbjct: 2009 DAN--SVMFANSLRTLSIVVGHSDSAWIEENLSDLKFLLEKSLENESVGVQSAIGNFVST 2066

Query: 2195 VFSAFPLEAATTPQDI-KLLYQRVQDLIQKHLAAVTTPQISLEPSNANSIISFALFVLNA 2253
            + +      +     I   ++  +    ++ L + +  +++L               +  
Sbjct: 2067 ILTLSNTHPSIAGNPIFNDIWTSIASWTERRLQSCSQIEVTLP-------------CVEC 2113

Query: 2254 LAEVQKNFIDPFIGLLLRVLQRLARDMGSSAGNHVRQGQRPEQDS-SVNSRPTVDPMVIS 2312
              + +K+ +   +   +R   ++A++  S        G +P  +S ++     VD  V S
Sbjct: 2114 FFKYKKDALHTLLPGFMRCFHKVAKEFLS-------LGSQPSGNSLNLQIVNAVDERV-S 2165

Query: 2313 NMKTVLKLISERVMASSEFRRSMGQTLQALLSEKGTDPSVLLCILDMIKAWIEDDYRLAS 2372
             +K++++L    +    + RR     L  ++ EK +   +   +L++++ WI +      
Sbjct: 2166 ILKSMIELGCSYISYLGDQRRWFLSALVQII-EKSSSYEICNYLLEIVRGWIMN------ 2218

Query: 2373 STGSVSSLNPKEIIAYLQKLSVVDRKSFPPSVQEEWDAKYLQLLYSLCGDTAKYQMALRQ 2432
                V     KE  A L K+   + + F  + Q +   KYL    S   D  + +     
Sbjct: 2219 --SPVPVPTVKEKAALLLKMVTFEGR-FSQNEQNDLFNKYL----SFIADIYEMEPYKNS 2271

Query: 2433 EYFHKVERQYMLGLRAKDPEMRKRFFKLYHDYVGKTLFARLQFIIQTQDWEAVSDVFWLK 2492
            E   ++E  Y+LG R  + ++++RF K  +      LF+R QF++ +Q WE++S+ +W+ 
Sbjct: 2272 ELTFRLEAVYLLGTRVANKKLKERFIKGLNSSFPSDLFSRFQFLLGSQHWESLSNTYWIV 2331

Query: 2493 QGLDLILAILVENEPITLAANSARVPALMTSGPVSDRMIMPQQAPDAQESLDGTSLSFDS 2552
            Q L++ L+   +   +       + P L +   +  R         AQ+    T +  ++
Sbjct: 2332 Q-LNIFLSRCFD---LNQRCQFYKKPKLFSCFSIYCREFDEDLTSQAQD----TEMLHNN 2383

Query: 2553 LTTRHAQFLNEASKLVVADVMAPLRELAFADPNVAYHLWVLVFPIVWVTLHKEEQVALAK 2612
            L        N+ S ++V+D + P+  L F++  +A +LW   F     +  K+E      
Sbjct: 2384 LLKYGIIDFNQNS-MLVSDFVLPVLSLQFSNSKIAEYLWRDFFNASVCSFTKDEIPLCIG 2442

Query: 2613 PIIALLSKDYHKRQQGCRPNVAQALLEGLHLSHPQPRMPSELIKYIGKTCNAWHTSIALL 2672
             II+ LS++YH R  G  PNV + +L  +  S     +P  L+ Y+ KT    H  I LL
Sbjct: 2443 SIISFLSREYHIRLLGKTPNVLETILTSIVSSDMPIPLPPHLLVYLSKTYGLHHYCILLL 2502

Query: 2673 ESHM----------MHMNEAKCSESLAELYRLLNEDDMRYGLWKRRSITAETRAGLSLVQ 2722
            E+ +          + +    C ++L+++Y  L+E D+ +GLW+RR+   ET    S  Q
Sbjct: 2503 ENSLQNNPGLSEDELTVYHKSCLDALSDIYYSLDEHDLYHGLWRRRANFLETEVATSHEQ 2562

Query: 2723 HGYWQQAQNLFYQAMIKATQGT--YNNTVPKAEMCLWEEQWLSCATQLGQWEVLADFGKG 2780
               W++AQ ++  A +K   G+  Y+ T    E   W + W+ CA +L QW+VL DF K 
Sbjct: 2563 CHEWEKAQLVYEHAQLKVCTGSLPYSPT----EHGFWLDHWILCAQKLNQWDVLFDFSKQ 2618

Query: 2781 VENYEILLDCLWKAPDWTYMKENVIPKAQVEETPKLRLIQS------FFTLHDKGTNGVG 2834
                E+ L+C W+  DW+  +++ + KA    +P   L +       +     +    V 
Sbjct: 2619 EGCAELYLECAWRLSDWS-TEQDTLEKATKSLSPFTSLRRHTADALLYLNKTQRKMGSVT 2677

Query: 2835 EAENLVSKGVELALEQWWQLPEMSVQSRMPLLQQFQQLVEVKESSKILLDIANGNKPXXX 2894
            E   ++ + ++ +L +W QLP+   QS + LL  FQ++VE++E+  I   + + N     
Sbjct: 2678 EFSRIIDECMQFSLRRWQQLPKRVYQSHVSLLHHFQEIVELQEAFGIYSQLNDTN----- 2732

Query: 2895 XXXXXXXXXXXFADLKDILETWRLRTPNEWDNMTVWYDLLQWRNEMYNSVIDAF------ 2948
                         D+K +L+ WR R PN WD++ +W DL+ WR  ++ S+   F      
Sbjct: 2733 ----IHNIDNKLRDIKVVLQGWRERLPNVWDDIDIWSDLIAWRQSVFKSINKVFLPLVSI 2788

Query: 2949 ----KDFGQTNPQLH-HLGYRDKAWNVNKLAHIARKQGLPDVCVTILDKMYGHATMEVQE 3003
                 +   TN   + + GY + AW +N+ AH+AR   LP+VC+  L K+Y    +E+QE
Sbjct: 2789 AQQSTNKSNTNSVSYLYRGYHELAWIINRFAHVARVHHLPEVCINQLTKIYTLPNIEIQE 2848

Query: 3004 AFVKICEQAKAYLEMKGELVSGLNLINNTNLEFFPVKNKAEIFRLRGDFLLKMNDCENAN 3063
            AF+K+ EQA+ + E   E+  GL +INNTNL +F  + KAE F L+G F  ++ + + AN
Sbjct: 2849 AFLKLREQAECHYESPSEMQLGLEVINNTNLMYFRNRQKAEFFTLKGMFQNRLGEKDEAN 2908

Query: 3064 VAYSNAITLFKHLPKAWISWGNYCDMVFKETKDEIWLEY-AVSCF-FQGIKYGVSNSRSH 3121
             A++ A+ +     KAW  WG Y D +F+    EI     AVSCF         SNS+  
Sbjct: 2909 QAFATAVQIDIGSGKAWSEWGLYHDELFQANPQEIHHACNAVSCFLQASSLLSSSNSKPL 2968

Query: 3122 LARILYLLSFDTQNEPAGRALDKYLEQLPHWVWLSWIPQLLLSLQRSEAQHCKLVLLKIA 3181
            L R+L+LLS D  +      +  +  ++P W W+ +IPQLL +L   E+ H + +L++IA
Sbjct: 2969 LTRVLWLLSVDDSHGSVSEVVSSFKSEIPTWNWIPFIPQLLSALSHRESIHARAILIQIA 3028

Query: 3182 QVYPQALYYWLRT----YLMERRDVATKTEMGRIXXXXXXXXXXXXXXXXXXSEGNARTS 3237
            + YPQ+L++ LRT    +LM ++  A                            GN+R  
Sbjct: 3029 KTYPQSLHFQLRTAYEDFLMLKKQQAANV-----------------------LRGNSR-- 3063

Query: 3238 NLGGGNMTSDNQVHQATQSGGAAVSHDGGNLQGQESDRSNVEGGTSAGHDQGQPSSTGAD 3297
             L   + +SDN+                 +L    S  S  +  +      G PSS  + 
Sbjct: 3064 -LRENDSSSDNK---------------SKDLSPSGSFSSVSQFNSK----NGSPSSIDSS 3103

Query: 3298 GSQMPARRNNGLGWVTSAASAFDAAKDIMEALRSKHTNLANELEVLLSEIGSRFVTLPEE 3357
                          +++   A++   D+   L++ +  LA  +E ++ +I +R  + PEE
Sbjct: 3104 EKHQ----------ISTVKPAWELIADVTSILKTAYPLLALTMETMVDQIHTRLKSFPEE 3153

Query: 3358 RLLAVVNALLHRCYKYPTATTGEVPQSLKKELSGVCRACFSQDAVNKHVDFVKEYKQDF- 3416
                ++ ALL+   +Y +        + +  +S      F+++ +   V   + + +DF 
Sbjct: 3154 DAYRLIVALLNDGLQYISRLGVVSKNTFQLPMSQANIQRFAENVLP--VSVREAFLRDFV 3211

Query: 3417 ERDLDPESATTFPATLAELTERLKHWKNVLQSNVEDRFPAILKLEEESKILRDFH---VV 3473
            E  LD          L    ++L+ W+   + N+ D+ P  L LE+ S  L +F      
Sbjct: 3212 ETKLD----------LLTYVDKLRMWRKKFE-NILDQRPKFLHLEQCSLYLSEFQHQKFD 3260

Query: 3474 DIELPGQYFTDQEVAPDHTVKLDRVGPDIPIVRRHGSSFRRLTLIGSDGSQRHFIVQTSL 3533
            ++E+PGQY  D+    D  V+L+R  P++ +VR H   ++RLTL G DG    F +Q   
Sbjct: 3261 EVEIPGQYLLDKNNNNDF-VRLERFVPNVDLVRGHTMCYKRLTLRGYDGKLYPFALQYPA 3319

Query: 3534 TPNARSDERMLQLFRVLNKMFDKHKESRQRHLAIHTPIIIPVWSQVRMVEDDLMYSTFLE 3593
            T ++R +ERMLQL    N +     E + R+ +   P  IP+ S +R++ D   Y T   
Sbjct: 3320 TRHSRREERMLQLLGTFNTVLRSKIEIQNRNFSFQIPSSIPLSSHMRIIADKPSYVTMQT 3379

Query: 3594 VYEINCARHNREADSPITIFKEQLNQAI------------------SGQVSPEAVVELRL 3635
            + +  C       D  I  + ++L   +                    Q+  +  ++LR+
Sbjct: 3380 ISDEYCKNRGMPLDYGIRFYFDRLQTGLIQLKRASASMLSNSTVEEKKQIFRQRALQLRM 3439

Query: 3636 QAYNEITKNIVNDNIFSQYMHKILPTGNHLWTFKKQFAIQVALSCFMSYMLQIGGRAPNK 3695
            Q    +  ++  ++I+  Y +K        W F++ F  Q A    M+Y+  IGGR+P K
Sbjct: 3440 QLLETLNSSVFPESIYYDYFYKTFERYCDFWFFRRTFTTQYAYMIIMTYVFNIGGRSPQK 3499

Query: 3696 ILFAKNTGKIFQNDFHPAYDPNGMIEFN-ELVPFRLTRNMQAFFSNFGVEGLIVSAMCSA 3754
            +   K++G++   D  P+   N  +  N E VPFRLT  +Q   S+ GVEGL+   + S 
Sbjct: 3500 LFIVKDSGQVMSQDLLPSMTSNQPVFHNTEAVPFRLTPPIQYLISDLGVEGLLSGLVMSI 3559

Query: 3755 AQSVVSPKQSQHIWHHLAMFFRDELLSWSWRRPLGIPSVPVAAGMINPLDFQQKVINNVE 3814
            AQS+ SP  +  I  +L+++ RDE+  WS ++   IP           +   + V  NVE
Sbjct: 3560 AQSLSSP--TTDIKQYLSLYVRDEVFWWSKQQRKPIP---------QGIQLFETVKVNVE 3608

Query: 3815 HVITRIKLISPHYLADEEENSSEPPQSVQRGVTDLVEAALSSRNLCMMDPTWHPW 3869
             +  RI +IS +   D   N +         + DLV  A + + L  MD  W  W
Sbjct: 3609 LLFRRISVISHNVPEDLPLNQT---------LVDLVSQATNPQQLAQMDQLWQAW 3654



 Score =  353 bits (905), Expect = 1e-95,   Method: Compositional matrix adjust.
 Identities = 236/834 (28%), Positives = 420/834 (50%), Gaps = 60/834 (7%)

Query: 74  HKLRNVVIEILNRLPHSEVLRPFVQDLLKLSLRVLTQDNEDNALLAIRIVFDLLRNFRPT 133
           ++L+   + ++    H +  + + Q  +   + ++  DNE+ A+  ++++ D+ + F+  
Sbjct: 73  NELKIEALTLIQSCAHRDEFKQYAQSCVLSFISLIKADNEEVAVFCLKVIMDIFKTFKFC 132

Query: 134 VEAEVQPFLDFVVTIYRNFPNTV-THFFDNP--NVSANIAAAVPNQHLDPTA---DAPGT 187
           +E+  QPF D V+ +  N P  + + F +NP  N   N   A  +     T+       +
Sbjct: 133 IESTAQPFFDLVLELSTNLPYLIPSIFVENPKSNEEENTTLAFGSYLSTETSIIQQRVNS 192

Query: 188 VAVPGGGQLNPSARSFKIVTESPLVVMFLFQLYAKLVQTNIPYLLPLMVSAISIKGPDKV 247
           +A+     L  +++SF++  E P++++ + Q Y +     +  ++P  +  + I  P  +
Sbjct: 193 LAI-STQPLELASQSFRVYVECPVIIVLILQAYRQAAFPGVQAIIPCFLKMVQIDVPIDI 251

Query: 248 PPHL----------------KTPFVELKGAQVKTLSFLTYLLKSNADHIKSYEESICKSI 291
             +                 K  +     AQVKTLSFL Y+L+++ + + S ++ I   +
Sbjct: 252 ASYAMIEKDSSIDFIEFIRNKYQYRNFFMAQVKTLSFLAYILRTHPNTL-SEKDIIPDIV 310

Query: 292 VNLLVTCPPDSVSIRKELLVGLKQVLNTEYRRGLFPLIDTLLDERVLIGTGRVCIETLRP 351
           + LL  CP D    RKELLV  + +L+T  +      +D LLD  +L+G G    + LRP
Sbjct: 311 IKLLRRCPFDMCFARKELLVATRHILSTNLKSLFVKKLDFLLDLNILLGNGVGTQKLLRP 370

Query: 352 LAYTLLAELVHYVRGDLSLPQLSRIIYLFSRNMHDSSLTLVIHTTSARLMLNLVEPIYEK 411
           LA++ LA+L+H+VR +L+  Q+ + I ++S NMHD +L++ + T  ARL+LN+V+    +
Sbjct: 371 LAFSTLADLLHHVRDELNETQIRKSIMIYSTNMHDLTLSIGLQTMGARLILNMVD----R 426

Query: 412 GIDQPSMDEARILLGRILDAFVGKFRTLKRTIPQLLEEGEEGKEHQNLRMKLEVPLQTVL 471
            I  PS+ +A  LL  I D+FV KF  L  ++ Q  ++  E +  +        P     
Sbjct: 427 MISLPSIPDAIFLLLSIFDSFVNKFSELNDSLDQFFKKKYEEEIKETKSPTRSSP----- 481

Query: 472 NLQPPLEYTKEINDYKSLIRTLVLGMKTIIWSI--THAHWPRPXXXXXXXXNLSVQPFRG 529
             +    ++  +ND   L + L+ G++ +++ +    +               +++PF  
Sbjct: 482 --RDLSSFSTSVNDGSFLFKNLMFGLRALMYGLRTCKSRCIEIGGEQFSGFLTNIKPFEA 539

Query: 530 LREDEV-----------RKTSGVLKSGVHC---------LALFKEKDEERDILQCFSQML 569
           +   ++           R     L++   C         ++      +E+D L+ F+ + 
Sbjct: 540 VTFQKLFFEVGKGFSYFRPEQVYLETFFCCEEESLDRPAISTLPRNKDEKDCLEVFATIF 599

Query: 570 AIMEARDIMDMFSFCMPDLFDCMITNNQLLHIFSSLLQAPKVLRPFTDVLINFLVSSKLD 629
             +E    + +F   +P  FD +  N  L HI   LL        F ++L+ FL+S +++
Sbjct: 600 IHLEPSIFLKVFETNLPTFFDQLKKNLTLFHIPQFLLSNESTSSKFLNILLRFLLS-RIE 658

Query: 630 ALKQPDSPAAKLVLQLFRFLFVAAAKAPESCERTLQPHVPVIMEVCMKSATEVEKPLGYM 689
            L   D     ++L+LFR  FV  +      E  L+P+V  I+  CMK A      L Y 
Sbjct: 659 ELGSSDIRHGSVLLRLFRLSFVTVSMFATENEPVLRPYVSEIIVKCMKLAPNSANSLNYY 718

Query: 690 HLLRSMFRALNIAKFDSLMRDLIPSLQPCLNMLLSMLDGPTSEDMRDLILELCLILPARL 749
           +LLR++FR +   +F+SL ++++P L   L    S+L    +   +DL  ELCL +P RL
Sbjct: 719 YLLRALFRGIGGGRFESLYKEVMPLLHALLEAFNSLLISARTPKEKDLFTELCLTIPVRL 778

Query: 750 SSLLPHIPRLMKPLVLALKGSDDLVSLALRTLEFWIDSLNPDFLEPSMANLMSDVILALW 809
           S LLP++  LM+PLV++LK S +LVS  LRT E  +D+L PDFL+P MA  + D++ ALW
Sbjct: 779 SLLLPYMSYLMRPLVMSLKSSQELVSQGLRTFELCLDNLTPDFLDPIMAPYIEDLMNALW 838

Query: 810 SHLRPPPYTWGTK--SLELLGKLGGRNRRFLKEPLALECKENPEHGLRLVLTFE 861
           SHL+P PY +     +L++LGKLGGRNR+ L    +L+    P +   L+L+ +
Sbjct: 839 SHLQPLPYNYNHSHTALKILGKLGGRNRKLLDRVQSLKNSPEPNNDFTLLLSIK 892



 Score =  171 bits (434), Expect = 9e-41,   Method: Compositional matrix adjust.
 Identities = 135/462 (29%), Positives = 220/462 (47%), Gaps = 33/462 (7%)

Query: 1103 SPPPSVRVAVFEELLPRLLHCCYGSTWXXXXXXXXXXXXXXXK-VSVDTLCIFQVRVVRG 1161
            +P  +  + +FE LL    H CY   W               +  S   L   QV ++  
Sbjct: 1096 NPERAFILPIFEVLLSDFRHKCYDPHWYKKYGGCFGLECLIEQDHSSKWLFDRQVDILTA 1155

Query: 1162 LIHVLKRLPMHA-NKEQEETNHVLTQVLRVVNNADEANSEHRRQSFQGVVEFLAVELFNP 1220
            L   LK          ++    VL Q+ R +  + +       +   G++  L +EL N 
Sbjct: 1156 LFFTLKDTTSEVPTVCKDHVMDVLKQLFRKIYASKDT------EIAPGILGHLVLELSNH 1209

Query: 1221 NTSIVVRKNVQACLSLLASRTGXXXXXXXXXXXXXXXXXXXXRSLRSKNIEQQVGTVTAL 1280
            N+  VVR + Q  LSLL+  +                     + LR+     Q+G + A+
Sbjct: 1210 NS--VVRSSTQKLLSLLSELSNTPIVKLVSPFKERLLSPIFAKPLRALPFHIQIGHIDAV 1267

Query: 1281 NFCLALRPPLLKLSPELVNFLQEALQIAEADETVWV-----TKMMNAKIIMTWNKLRTAC 1335
            N+C++L   L+  S EL+  + E   +AEAD+   +     +   NA +++   +LR  C
Sbjct: 1268 NYCISLGSELITFSDELIRLIHETTALAEADDDALIGIGKTSHFKNAALLI---RLRVVC 1324

Query: 1336 IELLCTAMAWGDLKAPNHSDLRAKIISMFFKSLTCRTTEIVNVAKEGLRQVVQQ-QRMPK 1394
            +ELL T +   D   P H+ LR  II +FFKSL  ++ E++  A  GL+  +Q+ Q++ K
Sbjct: 1325 VELLSTCILKIDFNNPQHAHLREGIIVVFFKSLYAKSKELIEAASLGLKNALQEDQKLSK 1384

Query: 1395 DLLQSSLRPILVNLAHTRSLTMPXXXXXXXXXXXXSNWFNVTLGAKLLDHLKKWLEPEKL 1454
            +LLQ++LRPIL N++  R L++             +N+F V +G KLLDHLK  LE    
Sbjct: 1385 ELLQTTLRPILYNISDYRRLSVAGLEGLGRLLRLLTNYFKVEIGRKLLDHLKALLENVDF 1444

Query: 1455 AQ-SQKSWKAGDEPKIAAAMIELFHLLPPAASKFLDDLVTLVID----LERALPEDQFYS 1509
             + S        E KI  A+I+LFHLLP  A++F+D+L+  V++    L+R  P   ++S
Sbjct: 1445 QKVSSLPLFCQTEMKIVRALIDLFHLLPNNANRFMDELLICVVEFSLRLQRTFP--NYFS 1502

Query: 1510 EINSPYRAPLAKFLNRYAVEAVDYFLARLSHPKYFRRFMYII 1551
            E       PL K++NRY  +A  +F+ R     +   F+ ++
Sbjct: 1503 E-------PLLKYVNRYPEDAWKFFMVRYDEAAFTSVFVELL 1537



 Score = 70.1 bits (170), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 41/162 (25%), Positives = 81/162 (50%), Gaps = 1/162 (0%)

Query: 1823 VHHRKELIKFGWNHLKREDNSSKQWAFVNVCHFLEAYQAPEKIILQVFIALLRTCQPENK 1882
            V H+ E++K        ED   KQ +   +  F+   Q P +++  V++ALL++   E +
Sbjct: 1771 VQHQTEMLKMCSLFGNSEDVMIKQLSIYVMSLFILRSQFPYELVNVVYMALLKSSPIEVR 1830

Query: 1883 LLVKQALDILMPALPRRLPPGDSRMPIWIRYTKKILVEEGHSIPNMIHIFQLIVRHADLF 1942
             LVK + D +   +     P   + PIW     +++  +  +I  +++++  I  H+D+F
Sbjct: 1831 HLVKSSFDNIFSYIFSE-EPESKKSPIWFELPLQVISSQSQNISQLLNVYDFISSHSDIF 1889

Query: 1943 YSCRAHFVPQMVNSLSRLGLPYNTTAENRRLAIELAGLVVAW 1984
               R  +VP +++SL + G   N   E R L++ L  +++ W
Sbjct: 1890 IEHRGRYVPILIDSLYKFGAIPNPNPEIRALSLGLIKVLLEW 1931

 Score =  569 bits (1466), Expect = e-161,   Method: Compositional matrix adjust.
 Identities = 399/1400 (28%), Positives = 677/1400 (48%), Gaps = 140/1400 (10%)

Query: 1826 RKELIKFGWNHLKREDNSSKQWAFVNVCHFLEAYQAPEKIILQVFIALLRTCQPENKLLV 1885
            +K++IKF WN +K ED   KQ A++   +F+  +  P K++ QVF+ALLR+   E + LV
Sbjct: 1883 KKDIIKFCWNFIKLEDTLIKQSAYLVTSYFISKFDFPIKVVTQVFVALLRSSHVEARYLV 1942

Query: 1886 KQALDILMPALPRRLPPGDSRMPIWIRYTKKILVEEGHSIPNMIHIFQLIVRHADLFYSC 1945
            KQ+LD+L P L  R+    +    WI + K+++VE   S  N++  +Q ++ H DLF++ 
Sbjct: 1943 KQSLDVLTPVLHERMNAAGTP-DTWINWVKRVMVENSSSQNNIL--YQFLISHPDLFFNS 1999

Query: 1946 RAHFVPQMVNSLSRLGLPYNTTAENRRLAIELAGLVVAWERQRQSEMKVVQESENTSQIG 2005
            R  F+  +++ ++++    N+ +++  LAI+LA L++ WE  +  E+  V  ++  S  G
Sbjct: 2000 RDLFISNIIHHMNKITFMSNSNSDSHTLAIDLASLILYWE-NKTLEITNVNNTKTDSD-G 2057

Query: 2006 DMLSPVIGGDPKRSSDVPTFGDDLSKRVKVEPGLQPLCVMSPGGASIPNIETPGSSGQPD 2065
            D    V+  D K  SD+                       +P  A    I    ++  P 
Sbjct: 2058 D----VVMSDSK--SDI-----------------------NPVEADTTAIIVDANNNSP- 2087

Query: 2066 EEYKPNAAMEEMIITFLIRVSLVIEPKDKESSSMYKQALDLLTQAL--EVWPNANVKFNY 2123
                 +  + E    FLIR       +  E+  +  +A+++L++ +  + W N NVK  Y
Sbjct: 2088 ----ISLHLREACTAFLIRYVCASNHRAIETE-LGLRAINILSELISDKHWTNVNVKLVY 2142

Query: 2124 LEKLLGNLTPSQSKDPATALAQGLDVMNKVLEKQPRLFIRNNINHISQILEPCFNNKMLD 2183
             EK L       S++        LDV+    + + + +I  N+  I  +LE C  +   D
Sbjct: 2143 FEKFLI-FQDLDSENILYYCMNALDVLYVFFKNKTKEWIMENLPTIQNLLEKCIKSDHHD 2201

Query: 2184 AGKSLCSLLKMVFSAFPLEAATTPQDIKLLYQRVQDLIQKHLAAVTTPQISLEPSNANSI 2243
              ++L  +L+++  A   +  +   + +      +  IQ   + +T          A   
Sbjct: 2202 VQEALQKVLQVIMKAIKAQGVSVIIEEE---SPGKTFIQMLTSVITQDLQETSSVTAGVT 2258

Query: 2244 ISFALFVLNALAEVQKNFID---PFIGLLLRVLQRLARDMGSSAGNHVRQGQRPEQDSSV 2300
            +++ LF+         NF D   P +  L++   +L +D       H+   Q  +  +  
Sbjct: 2259 LAWVLFM---------NFPDNIVPLLTPLMKTFSKLCKD-------HLSISQPKDAMALE 2302

Query: 2301 NSRPTVDPMVISNMKTVLKLISERVMASSEFRRSMGQTLQALLSEKGTDPSVLLCILDMI 2360
             +R T        ++ VL ++S +V    + RR    T+ ALL +   D + L  I++M 
Sbjct: 2303 EARITTKL-----LEKVLYILSLKVSLLGDSRRPFLSTV-ALLIDHSMDQNFLRKIVNMS 2356

Query: 2361 KAWIEDDYRLASSTGSVSSLNPKEIIAYLQKLSVVDRKSFPPSVQEEWDAKYLQLLYSLC 2420
            ++WI +     +          KE  A L K+   + +   PS+         +L Y + 
Sbjct: 2357 RSWIFNTEIFPTV---------KEKAAILTKMLAFEIRG-EPSLS--------KLFYEIV 2398

Query: 2421 GDTAKYQMALRQEYFHKVERQYMLGLRAKDPEMRKRFFKLYHDYVGKTLFARLQFIIQTQ 2480
                  +     E   ++E+ +++G R +D  +RKRF  +  + + + +  RL ++I+ Q
Sbjct: 2399 LKLFDQEHFNNTEITVRMEQPFLVGTRVEDIGIRKRFMTILDNSLERDIKERLYYVIRDQ 2458

Query: 2481 DWEAVSDVFWLKQGLDLILAILVENEPITLAANSARVPALMTSGPVSDRMIMPQQAPDAQ 2540
            +WE ++D  WL Q L L+       + ++L       P      P   +  +P+ A    
Sbjct: 2459 NWEFIADYPWLNQALQLLYGSFNREKELSLKNIYCLSP------PSILQEYLPENAEMVT 2512

Query: 2541 ESLDGTSLSFDSLTTRHAQFLNEASKLVVADVMAPLRELAFADPNVAYHLWVLVFPIVWV 2600
            E  D   L   +    H   +    +++ +D +  L E+ + DP   +  WV +FP V+ 
Sbjct: 2513 EVND---LELSNFVKGHIASMQGLCRIISSDFIDSLIEIFYQDPKAIHRAWVTLFPQVYK 2569

Query: 2601 TLHKEEQVALAKPIIALLSKDYHKRQQGCRPNVAQALLEGLHLSHPQPRMPSELIKYIGK 2660
            ++ K E+    + II LLSK YH RQ   R NV   LL+ +        +P  L+KY+  
Sbjct: 2570 SIPKNEKYGFVRSIITLLSKPYHTRQISSRTNVINMLLDSIS-KIESLELPPHLVKYLAI 2628

Query: 2661 TCNAWHTSIALLES----------HMMHMNEAKCSESLAELYRLLNEDDMRYGLWKRRSI 2710
            + NAW+ SI +LES           ++  NE    ++L ELY  L E+DM YGLW+RR+ 
Sbjct: 2629 SYNAWYQSINILESIQSNTSIDNTKIIEANE----DALLELYVNLQEEDMFYGLWRRRAK 2684

Query: 2711 TAETRAGLSLVQHGYWQQAQNLFYQAMIKATQGTYNNTVPKAEMCLWEEQWLSCATQLGQ 2770
              ET  GLS  Q G W +AQ L+  A +KA  G       ++E  LWE+ W+ CA +L  
Sbjct: 2685 YTETNIGLSYEQIGLWDKAQQLYEVAQVKARSGAL--PYSQSEYALWEDNWIQCAEKLQH 2742

Query: 2771 WEVLADFGKGVENYEILLDCLWKAPDWTYMK---ENVIPKAQVEETPKLRLIQSFFTLHD 2827
            W+VL +  K     ++LL+C W+  DW   +   E  +       TP+ ++ ++F  L +
Sbjct: 2743 WDVLTELAKHEGFTDLLLECGWRVADWNSDRDALEQSVKSVMDVPTPRRQMFKTFLALQN 2802

Query: 2828 --KGTNGVGEAENLVSKGVELALEQWWQLPEMSVQSRMPLLQQFQQLVEVKESSKILLDI 2885
              +   G  E   L  +G++L+L +W  LP     +   LL  FQQ +E  E+++I  ++
Sbjct: 2803 FAESRKGDQEVRKLCDEGIQLSLIKWVSLPIRYTPAHKWLLHGFQQYMEFLEATQIYANL 2862

Query: 2886 ANGNKPXXXXXXXXXXXXXXFADLKDILETWRLRTPNEWDNMTVWYDLLQWRNEMYNSVI 2945
                                  ++K IL+ WR R PN WD++ +W DL+ WR   +  + 
Sbjct: 2863 HTTT---------VQNLDSKAQEIKRILQAWRDRLPNTWDDVNMWNDLVTWRQHAFQVIN 2913

Query: 2946 DAF--------KDFGQTNPQLH-HLGYRDKAWNVNKLAHIARKQGLPDVCVTILDKMYGH 2996
            +A+        +    +N   H + GY + AW +N+ AH+ARK  +PDVC++ L ++Y  
Sbjct: 2914 NAYLPLIPALQQSNSNSNINTHAYRGYHEIAWVINRFAHVARKHNMPDVCISQLARIYTL 2973

Query: 2997 ATMEVQEAFVKICEQAKAYLEMKGELVSGLNLINNTNLEFFPVKNKAEIFRLRGDFLLKM 3056
              +E+QEAF+K+ EQAK + +   EL +GL++I+NTNL +F    KAE F L+G FL K+
Sbjct: 2974 PNIEIQEAFLKLREQAKCHYQNMNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKL 3033

Query: 3057 NDCENANVAYSNAITLFKHLPKAWISWGNYCDMVFKETKDEI-WLEYAVSCFFQGIK-YG 3114
               E AN A++ A+ +  +L KAW  WG + D    E  + I +   A+SC+ Q    Y 
Sbjct: 3034 RAYEEANQAFATAVQIDLNLAKAWAQWGFFNDRRLSEEPNNISFASNAISCYLQAAGLYK 3093

Query: 3115 VSNSRSHLARILYLLSFDTQNEPAGRALDKYLEQLPHWVWLSWIPQLLLSLQRSEAQHCK 3174
             S  R  L RIL+L+S D  +     A D +  ++P W W+++IPQLL SL   EA   +
Sbjct: 3094 NSKIRELLCRILWLISIDDASGMLTNAFDSFRGEIPVWYWITFIPQLLTSLSHKEANMVR 3153

Query: 3175 LVLLKIAQVYPQALYYWLRT 3194
             +L++IA+ YPQAL++ LRT
Sbjct: 3154 HILIRIAKSYPQALHFQLRT 3173



 Score =  360 bits (925), Expect = 5e-98,   Method: Compositional matrix adjust.
 Identities = 301/1124 (26%), Positives = 515/1124 (45%), Gaps = 147/1124 (13%)

Query: 6    SSNMEQHSQKLLEPDLPVQVRLQLAMEVRDSLEMTHTP-DYLNFLRCYFRAFSAILSNFT 64
            +  +EQ + +  + D  +Q R     E+ D +E+ ++P DY  FL+         L    
Sbjct: 4    TEQIEQFASRFRDDDATLQSRYSTLSELYDIMELLNSPEDYHFFLQAVIPLLLNQLKEVP 63

Query: 65   APQGTENAEHKLRNVVIEILNRLPHSEVLRPFVQDLLKLSLRVLTQDNEDNALLAIRIVF 124
                  + E KLRN +++I NR   ++  +P+  ++L+  L VL ++NE+N +L ++++ 
Sbjct: 64   ISYDAHSPEQKLRNSMLDIFNRCLMNQTFQPYAMEVLEFLLSVLPKENEENGILCMKVLT 123

Query: 125  DLLRNFRPTVEAEVQPFLDFVVTIYRNFPNTVTHFFDNPNVSANIAAAVPNQHLDPTADA 184
             L ++F+  ++ ++  F+  ++ IY+N PN +   F     +       P +   P AD 
Sbjct: 124  TLFKSFKSILQDKLDSFIRIIIQIYKNTPNLINQTFYEAGKAEQGDLDSPKE---PQADE 180

Query: 185  ----------------------PGTVAVPGGGQLNPSARSFKIVTESPLVVMFLFQLYAK 222
                                  P          L  S  SFKI++E P+ ++ L+  Y +
Sbjct: 181  LLDEFSKNDEEKDFPSKQSSTEPRFENSTSSNGLRSSMFSFKILSECPITMVTLYSSYKQ 240

Query: 223  LVQTNIPYLLPLMVSAISIK---------GPDKVPPHLKTPFVELKG---------AQVK 264
            L  T++P   PL+++ ++I+           +    H  +   E+           AQ+K
Sbjct: 241  LTSTSLPEFTPLIMNLLNIQIKQQQEAREQAESRGEHFTSISTEIINRPAYCDFILAQIK 300

Query: 265  TLSFLTYLLKSN--ADHIKSYEESICKSIVNLLVTCPPDSVSIRKELLVGLKQVLNTEYR 322
              SFL Y+       + ++ Y   +   I+ LL  CP +  S RKELL   + +L+T Y+
Sbjct: 301  ATSFLAYVFIRGYAPEFLQDYVNFVPDLIIRLLQDCPSELSSARKELLHATRHILSTNYK 360

Query: 323  RGLFPLIDTLLDERVLIGTGRVCIETLRPLAYTLLAELVHYVRGDLSLPQLSRIIYLFSR 382
            +   P +D L DER+LIG G    ETLRPLAY+ +A+ +H +R +L L ++ + I +++ 
Sbjct: 361  KLFLPKLDYLFDERILIGNGFTMHETLRPLAYSTVADFIHNIRSELQLSEIEKTIKIYTG 420

Query: 383  NMHDSSLTLVIHTTSARLMLNLVEPIYEKGIDQP-SMDEARILLGRILDAFVGKFRTLKR 441
             + D SL L +   SA+L+LNLVE I + G + P     A+ LL  I+D+++ +F+TL R
Sbjct: 421  YLLDESLALTVQIMSAKLLLNLVERILKLGKENPQEAPRAKKLLMIIIDSYMNRFKTLNR 480

Query: 442  ---TIPQLLEEGEEGKEHQNLRMKLEV--------------------------PLQTVLN 472
               TI +     E  K+ +  ++K  +                          P +  +N
Sbjct: 481  QYDTIMKYYGRYETHKKEKAEKLKNSIQDNDKESEEFMRKVLEPSDDDHLMPQPKKEDIN 540

Query: 473  LQPPLEYTKE-----------------------------INDYKSLIRTLVLGMKTIIWS 503
              P +E T+                              I D   L RTL+  +KTII  
Sbjct: 541  DSPDVEMTESDKVVKNDVEMFDIKNYAPILLLPTPTNDPIKDAFYLYRTLMSFLKTIIHD 600

Query: 504  ITHAHWPRPXXXXXXXXNLSVQPFRGLREDEVRKTSGVLKSGVHCLALFKEKDEER---- 559
            +   + P P         L     R    +EV     +    +  L  FK+ +E+     
Sbjct: 601  LKVFN-PPPNEYTVANPKLWASVSRVFSYEEVIVFKDLFHECIIGLKFFKDHNEKLSPET 659

Query: 560  -----DILQCFSQMLAIMEARDIMDMFSFC----------------MPDLFDCMITNNQL 598
                 DI      + A  +AR++MD  +F                 +P +++ M+ ++ L
Sbjct: 660  TKKHFDISMPSLPVSATKDARELMDYLAFMFMQMDNATFNEIIEQELPFVYERMLEDSGL 719

Query: 599  LHIFSSLLQAPKVLRPFTDVLINFLVSSKLDALKQPDSPAAKLVLQLFRFLFVAAAKAPE 658
            LH+  S L +      F  +L+ FL   KL  L   D   + ++++LF+  F++    P 
Sbjct: 720  LHVAQSFLTSEITSPNFAGILLRFL-KGKLKDLGNVDFNTSNVLIRLFKLSFMSVNLFPN 778

Query: 659  SCERTLQPHVPVIMEVCMKSATEVEKPLGYMHLLRSMFRALNIAKFDSLMRDLIPSLQPC 718
              E  L PH+  ++   +K +T  E+PL Y +L+R++FR++   +F++L R + P LQ  
Sbjct: 779  INEVVLLPHLNDLILNSLKYSTTAEEPLVYFYLIRTLFRSIGGGRFENLYRSIKPILQVL 838

Query: 719  LNMLLSMLDGPTSEDMRDLILELCLILPARLSSLLPHIPRLMKPLVLALKGSDDLVSLAL 778
            L  L  M+        R+L +ELC+ +P RLS L P++P LMKPLV AL+   DLVS  L
Sbjct: 839  LQSLNQMILTARLPHERELYVELCITVPVRLSVLAPYLPFLMKPLVFALQQYPDLVSQGL 898

Query: 779  RTLEFWIDSLNPDFLEPSMANLMSDVILALWSHLRPPPYTWGTKS--LELLGKLGGRNRR 836
            RTLE  ID+L  ++ +P +  ++ DV  AL++ L+P P+        + +LGKLGGRNR+
Sbjct: 899  RTLELCIDNLTAEYFDPIIEPVIDDVSKALFNLLQPQPFNHAISHNVVRILGKLGGRNRQ 958

Query: 837  FLKEPLALECKENPEHGLRLVLTFE-PATPFLVPLDRC--IHFAVSAVMQGNSMEAFYRK 893
            FLK P  L   E  E  +  +  F+    P  VPL     I  A++ ++Q    +  YRK
Sbjct: 959  FLKPPTDL--TEKTELDIDAIADFKINGMPEDVPLSVTPGIQSALN-ILQSYKSDIHYRK 1015

Query: 894  QALQFIRVCLDSLLNLRENVPGEGVSPGVLGTLLISSLDPSRRRNDASDMKGDLG-VKTK 952
             A +++  C+  L+            P     LL ++++  +      +   DL     K
Sbjct: 1016 SAYKYL-TCVLLLM-----TKSSAEFPTNYTELLKTAVNSIKLERIGIEKNFDLEPTVNK 1069

Query: 953  TQLLAEKSVFKVLLVAIIAANSDTSLTDEKDDFVVDLCRHFAML 996
                 ++++F  LL ++  A S   L D+  D + +L  HF +L
Sbjct: 1070 RDYSNQENLFLRLLESVFYATSIKELKDDAMDLLNNLLDHFCLL 1113



 Score =  211 bits (536), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 157/580 (27%), Positives = 276/580 (47%), Gaps = 76/580 (13%)

Query: 3323 KDIMEALRSKHTNLANELEVLLSEIGSRFVTLPEERLLAVVNALL------HRCYKYPTA 3376
            +++   L++ +  LA  LE L+++I  RF +  +E L  ++N LL      +    +P  
Sbjct: 3209 QELNNILKTAYPLLALSLESLVAQINDRFKSTTDEDLFRLINVLLIDGTLNYNRLPFPRK 3268

Query: 3377 TTGEVPQSLKKEL---SGVCRACFSQDAVNKHVDFVKEYKQDFERDLDPESATTFPATLA 3433
               ++P++ +K L   S    A + +   N   DF+ + K D+E  +             
Sbjct: 3269 N-PKLPENTEKNLVKFSTTLLAPYIRPKFN--ADFI-DNKPDYETYI------------- 3311

Query: 3434 ELTERLKHWKNVLQSNVEDRFPAILKLEEESKILRDFH---VVDIELPGQYFTDQEVAPD 3490
               +RL++W+  L++ + DR      LE     L +FH     DIE+PGQY  +++    
Sbjct: 3312 ---KRLRYWRRRLENKL-DRASKKENLEVLCPHLSNFHHQKFEDIEIPGQYLLNKDNNV- 3366

Query: 3491 HTVKLDRVGPDIPIVRRHGSSFRRLTLIGSDGSQRHFIVQTSLTPNARSDERMLQLFRVL 3550
            H +K+ R  P +  VR   SS+RRL + G DGS   F VQ     ++R +ERM QL+R+ 
Sbjct: 3367 HFIKIARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVRHSRREERMFQLYRLF 3426

Query: 3551 NKMFDKHKESRQRHLAIHTPIIIPVWSQVRMVEDDLMYSTFLEVYEINCARHNREADSPI 3610
            NK   K+ E+R+R +  + PI IP+  QVR++ D + ++T  E++   C +   + D   
Sbjct: 3427 NKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCKKKGFDPDDIQ 3486

Query: 3611 TIFKEQLNQAISGQVSPEAVVELRLQAYNEITKNIVNDNIFSQYMHKILPTGNHLWTFKK 3670
                ++LN A    +    +  L+++ +N I    V  N+   +   +       W F+K
Sbjct: 3487 DFMADKLNAAHDDALPAPDMTILKVEIFNSIQTMFVPSNVLKDHFTSLFTQFEDFWLFRK 3546

Query: 3671 QFAIQVALSCFMSYMLQIGGRAPNKILFAKNTGKIFQNDFHPAYDP-------------- 3716
            QFA Q +   FMSYM+ I  R P+KI   K +G +F  +  P+  P              
Sbjct: 3547 QFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSRFPYERVKPLLKNHDLS 3606

Query: 3717 ----NGMIEFNELVPFRLTRNMQAFFSNFGVEGLIVSAMCSAAQSVVSPKQSQHIWHHLA 3772
                + +   NE VPFRLT N+Q+   +  +EG+    + + +++++ P    + +  LA
Sbjct: 3607 LPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELNTY--LA 3664

Query: 3773 MFFRDELLSW--SWRRPLGIPSVPVAAGMINPLDFQQKVINNVEHVITRIKLISPHYLAD 3830
            +F RDE++SW  +  RP+          + NP   ++ V  NV+ +I ++  +       
Sbjct: 3665 LFIRDEIISWFSNLHRPI----------IENP-QLREMVQTNVDLIIRKVAQLG------ 3707

Query: 3831 EEENSSEPPQSVQRGVTDLVEAALSSRNLCMMDPTWHPWF 3870
               + +  P    + + D + +A+S RNL   D  + PWF
Sbjct: 3708 ---HLNSTPTVTTQFILDCIGSAVSPRNLARTDVNFMPWF 3744



 Score =  175 bits (444), Expect = 7e-42,   Method: Compositional matrix adjust.
 Identities = 126/460 (27%), Positives = 212/460 (46%), Gaps = 18/460 (3%)

Query: 1101 VYSPPPSVRVAVFEELLPRLLHCCYGSTWXXXXXXXXXXXXXXXKVSVDTLCI--FQVRV 1158
            +Y    ++  +   EL  + +H CY  T+                V   ++ +  +Q  +
Sbjct: 1178 IYGEELALSHSFIPELAKQFIHLCYDETYYNKRGGVLGIKVLIDNVKSSSVFLKKYQYNL 1237

Query: 1159 VRGLIHVLKRLPMHANKEQEETNHVLTQVLRVVNNADEANSEHRRQSFQGVVEFLAVELF 1218
              GL+ VLK     A     ++   L   L  +  AD    +   +  +  +  +  EL 
Sbjct: 1238 ANGLLFVLKDTQSEAPSAITDSAEKLLIDLLSITFADVKEEDLGNKVLENTLTDIVCELS 1297

Query: 1219 NPNTSIVVRKNVQACLSLLASRTGXXXXXXXXXXXXXXXXXXXXRSLRSKNIEQQVGTVT 1278
            N N    VR   Q  L  +++ TG                    + LR+     Q+G V 
Sbjct: 1298 NANPK--VRNACQKSLHTISNLTGIPIVKLMDHSKQFLLSPIFAKPLRALPFTMQIGNVD 1355

Query: 1279 ALNFCLALRPPLLKLSPELVNFLQEALQIAEADETVWVTKMMNAKIIMTWNKL---RTAC 1335
            A+ FCL+L    L  + EL   LQE++ +A+A++    T +       T  +L   R AC
Sbjct: 1356 AITFCLSLPNTFLTFNEELFRLLQESIVLADAEDESLSTNIQKTTEYSTSEQLVQLRIAC 1415

Query: 1336 IELLCTAMAWGDLKAPNHSDLRAKIISMFFKSLTCRTTEIVNVAKEGLR-QVVQQQRMPK 1394
            I+LL  A+   +       ++R +I+++FFK++   + EI+N   E L+  + +  ++PK
Sbjct: 1416 IKLLAIALKNEEFATAQQGNIRIRILAVFFKTMLKTSPEIINTTYEALKGSLAENSKLPK 1475

Query: 1395 DLLQSSLRPILVNLAHTRSLTMPXXXXXXXXXXXXSNWFNVTLGAKLLDHLKKWLEPEKL 1454
            +LLQ+ L+P+L+NL+  + LT+P              +F V +G KLLDHL  W   E L
Sbjct: 1476 ELLQNGLKPLLMNLSDHQKLTVPGLDALSKLLELLIAYFKVEIGRKLLDHLTAWCRVEVL 1535

Query: 1455 AQSQKSWKAGDEP-KIAAAMIELFHLLPPAASKFLDDLVTLVIDLERALPEDQFYSEINS 1513
                    A   P KI  ++I +FHLLPP A  FL+DL+  V+ LER L       +++S
Sbjct: 1536 DTLFGQDLAEQMPTKIIVSIINIFHLLPPQADMFLNDLLLKVMLLERKL-----RLQLDS 1590

Query: 1514 PYRAPLAKFLNRYAVEAVDYFLARLSHPKYFRRFMYIICS 1553
            P+R PLA++LNR+     +YF   ++     R+ +  +C+
Sbjct: 1591 PFRTPLARYLNRFHNPVTEYFKKNMT----LRQLVLFMCN 1626