Score =  617 bits (1591), Expect = e-176,   Method: Compositional matrix adjust.
 Identities = 420/1215 (34%), Positives = 612/1215 (50%), Gaps = 190/1215 (15%)

Query: 2379 LQLLIANKRLVLCPSNVDNDLMCCFC---INLMA-------LLRDKRLTAQNLAVDLLKY 2428
            L++L  N+ L+L P N D + + C     INL A       L  + R+T  ++ +     
Sbjct: 2120 LRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAGSVEGFGLEAEARMTTWHIMI----- 2174

Query: 2429 LVVHRRPSLEDLLVSKPNQGQQMDILHGGLDKLLTGSTTAFFEWLQSSQQTISKV----- 2483
                  PS  D+   +P+ G   DI  G    L+      + E + S +Q + ++     
Sbjct: 2175 ------PS--DI---EPDGGYSQDISEGR-QLLIKAVNRVWTELIHSKKQVLEELFKVSL 2222

Query: 2484 ----------------LDQCALIMWVQYIT--------GSAKFPGVRIKGMEVRR----- 2514
                            +++  L  W  ++         G A  P  + K   V       
Sbjct: 2223 PVNDRGHVDIALARPLIEEAGLKCWQNHLAHEKKCISRGEALVPTTQSKLSRVSSGFGLS 2282

Query: 2515 KKDMGRKLREIAKLD--SRHWEQINERRY-NLDLVRDVMSTELRAIRQDKYGWILHGESE 2571
            K    R+ R+ + L   S   ++I++  + ++ +VRD++ T+ +  ++ +   + +   E
Sbjct: 2283 KLTGSRRNRKESGLHKHSPSPQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEE 2342

Query: 2572 WQSQLQQLVHERGIFPVRQLSTEPAWQLCAVEGPYRMRKKLEPSKFKIDTIHNVLASNLG 2631
            W     +L+ ERG++     S    W L   EGP RMRKK+     + D  +N       
Sbjct: 2343 WCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKM----VRNDMFYNHYPY--- 2395

Query: 2632 LDDVKITKKEDGHMVMTSGSDTMSGLNLLTYDTERKDLDAADFASFKDEDDIFKGGSTVS 2691
               V  T++E       S          ++YD++   L  A       +D I +      
Sbjct: 2396 ---VPETEQE------ASVGKPARYRRAISYDSKEYYLRLASGNPAIVQDAIVE------ 2440

Query: 2692 PPIGWTDDKSSINEQSLHSATEHGAKSSSFSYHMTESVHG--KSEFNSPRRAPSVKGTDT 2749
                      S   ++     EHG  + +        V G  K      R AP   G D 
Sbjct: 2441 ----------SSEGEATQQEPEHGEDTIA-------KVKGLVKPPLKRSRSAPD--GGDE 2481

Query: 2750 RTSEDK----------SEKELLDNGEYLIRPYLEPSEKIRHKYNCERVAGLDKHDGIFLI 2799
             T E             E+E  DN   L+R  LE  EKI+H Y C RV GLD  +G+ L 
Sbjct: 2482 ETQEQLQDQIAESGSIEEEEKTDNAT-LLR-LLEEGEKIQHMYRCARVQGLDTSEGLLLF 2539

Query: 2800 GELSLYIIENFYIDDSNCIYEKGNEDELSVIDQALGVKKDVLGSCDSHQKSPSTWGATAK 2859
            G+   Y+I+ F +  +  I +                    + +   +   P        
Sbjct: 2540 GKEHFYVIDGFTMTATREIRD--------------------IETLPPNMHEPI------- 2572

Query: 2860 VLLGGRAWAYNGGAWGKEKLCSSSNLPHPWHMWKLDSVHELLKRDYQLRPVAIEIFSMDG 2919
            +  G R      G    ++ CS         ++  + + E+ KR Y L+P+A+E+FS DG
Sbjct: 2573 IPRGARQ-----GPSQLKRTCS---------IFAYEDIKEVHKRRYLLQPIAVEVFSGDG 2618

Query: 2920 CNELLVFHKKEREDVFKNLTAMNLPRNSMLDTTISASSKQDSG---EGSRLFKIMA--KS 2974
             N LL F K  R  V++   A+ +P  S+ D++ S S ++ +    +GS L   +   KS
Sbjct: 2619 RNYLLAFQKGIRNKVYQRFLAV-VP--SLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKS 2675

Query: 2975 FSKRWQSGEITNFQYLMHLNTLAGRGYSDLTQYPVFPWVLADYESDTLDLRNPQTFRKLD 3034
             ++RW+ GEI+NFQYLMHLNTLAGR Y+DL QYPVFPW+L+DY+S+ +DL NP+TFR L 
Sbjct: 2676 VTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLA 2735

Query: 3035 KPMGCQTEGGEEEFRKRYDSWDDP--EVPKFHYGSHYSSAGIVLFYLLRLPPFSMENQKL 3092
            KPMG QT+    +++KRY  W+DP  E P +HYG+HYSSA IV  YL+R+ PF+    +L
Sbjct: 2736 KPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRL 2795

Query: 3093 QGGQFDHADRLFNSVKDTWVSAAGKSNTSDVKELIPEFYYLPEFLENQFNLDLGEKQSGE 3152
            QGG FD ADR+F+SV++ W SA+ K N +DVKELIPEF+YLPEFL N  N DLG KQ+G 
Sbjct: 2796 QGGHFDLADRMFHSVREAWYSAS-KHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGT 2854

Query: 3153 KVGDVVLPPWAKGSSREFIRKHREALESDYVSENLHHWIDLIFGYKQRGKAAEDAVNVFY 3212
            K+GDV+LPPWAKG  REFIR HREALE DYVS +LH WIDLIFGYKQ+G AA +AVNVF+
Sbjct: 2855 KLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFH 2914

Query: 3213 HYTYEGNVDIDSVSDPTMKASILAQINHFGQTPKQLFQKPHPQRRTDRK---------VL 3263
            H  YEG VDI +++DP  + + +  IN+FGQ PKQLF+KPHP +R   +         V 
Sbjct: 2915 HLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGISVP 2974

Query: 3264 PHPLRYSAYLTHQE--------IRKTTSSVSQIVTYNDKILIAAANSFLKPVNYSEYISW 3315
            P       +  H +        +++    V QIV  +  IL    N  L P  +++  +W
Sbjct: 2975 PGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPAWNKTFAW 3034

Query: 3316 GFPDRSLRILTYDQDKLVSTHENLHGGSQIQCTGVSHDGNILTTGGDDGVVAVWRFFKDG 3375
            G+ D S R+ TY+ DK V+ +E L    QI C  V  +  ++ TGG   VV VW      
Sbjct: 3035 GYADLSCRLGTYESDKAVTVYECLSEWGQILC-AVCPNPKLVITGGTSTVVCVWEMGTSK 3093

Query: 3376 TR-RLLRMEKALCAHTAKITCIYVSQPYSLIVSGSDDCSVILWDLTSLAFVKQLPRFPAS 3434
             + + L +++AL  HT  +TC   S  Y +IVSGS D + I+WDL  L+F+ QL    A 
Sbjct: 3094 EKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAP 3153

Query: 3435 VSALHVNNLTGEILTGAGVLFAVWSVNGDCLAVVNTSQLPSDLILSVASTTNSDWQDTNW 3494
            VSAL +N LTG+I++ AG    VWS+NG+ +  VNT    S  I+    +  ++W   N 
Sbjct: 3154 VSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNV 3213

Query: 3495 YVTGHQSGAVKVWKM 3509
             VTGH  G V+ W+M
Sbjct: 3214 IVTGHSDGVVRFWRM 3228



 Score =  108 bits (271), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 108/419 (25%), Positives = 172/419 (41%), Gaps = 48/419 (11%)

Query: 1092 GERTWPPVSGYSFVCWFQFQNFF---RSHPKEAEKTSKGSYSKRNGQVMRIFSVGAVDDA 1148
            GER +PP SG S+ CWF  ++F     +HP       + + S     V     + A D +
Sbjct: 1090 GERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRS 1149

Query: 1149 NTLYAELYLHDNGVFTIATSNSSSLSFP-------GIEMEEGKWHHLAVVHSKPNALAGL 1201
              +  +  L  N V   +  +S     P       G  + EG+WHHLA++ S+     G+
Sbjct: 1150 LIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELVVEGQWHHLALLMSR-----GM 1204

Query: 1202 FQSSVASLYLDGKLRHTGKLGYSPS----------PFGKSLQVTLGTPAIRAKVSDLSWR 1251
             ++S A+LYLDG+L  T KL Y  S          P   ++   +GTP  + +++ L WR
Sbjct: 1205 LKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWR 1264

Query: 1252 LRCCYLFEEVLTPGSICFMYILGQGYRGLFQDTDLLRFVPNWACGGEVMAILDSLELEVI 1311
            L   +  EEVL P S+  +Y LG  Y G FQ                V       + E +
Sbjct: 1265 LGPTHFLEEVLPPSSVTTIYELGPNYVGSFQ---------------AVCVPCKDAKSEGV 1309

Query: 1312 APSGSQRV-DSAMKQGNSRLESSGIVWDMERLRNLSLQLSGKKLIFAFDGTSSDAFRASG 1370
             PS    V +  +  G   L  S +   + R+R +  +L  K +      +S +   A+ 
Sbjct: 1310 TPSPVSLVAEEKVSFGLYALSVSSLT--VARIRKVYNKLDSKAIAKQLGISSHE--NATP 1365

Query: 1371 TLSLLNLVDPTSAAASPIGGIPRYGRLSGDVYVCNQCTIGDTVQTVGGIPVVLALVEAAE 1430
               + N     +  A  IG     G L    +V     +  T+Q +GG   +L LV  A 
Sbjct: 1366 VKLVHNAAGHLNGPARTIGAA-LIGYLGVRTFVPK--PVATTLQYIGGAAAILGLVAMAS 1422

Query: 1431 TRDXXXXXXXXXXXXXXXXXQNVKDMQSLRGYHLLALFLHRRMSLFDMQSLDIFFRIAA 1489
              +                    K+M+ ++GY LLA+ L ++ SL +   L + F +  
Sbjct: 1423 DVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVG 1481

 Score =  597 bits (1540), Expect = e-170,   Method: Compositional matrix adjust.
 Identities = 332/845 (39%), Positives = 479/845 (56%), Gaps = 112/845 (13%)

Query: 2782 YNCERVAGLDKHDGIFLIGELSLYIIENFYIDDSNCIYEKGNEDELSVIDQALGVKKDVL 2841
            YNC  V G+DK +GI +   + +YI + +Y D+        N  ++S +++ +       
Sbjct: 2816 YNCGSVDGMDKIEGILIFCPVYMYIFDGYYKDE--------NTGDISEVEEKIN------ 2861

Query: 2842 GSCDSHQKSPSTWGATAKVLLGGRAWAYNGGAWGKEKLCSSSNLPHPWHMWKLDSVHELL 2901
                      S W     VL              K+K+       H +  W  + + ++L
Sbjct: 2862 ----------SEWLPEGTVLPM------------KKKII------HYFLKWAYEDIRDVL 2893

Query: 2902 KRDYQLRPVAIEIFSMDGCNELLVFHKK-EREDVFKNLTAMNLPRNSMLDTTISASSKQD 2960
            KR Y LR VA+EIFS DG N L+V+  +  R++V+  L       N     TI   ++  
Sbjct: 2894 KRRYLLRQVALEIFSTDGRNNLVVYRDEPTRDEVYHTLV-----NNVSSHNTIGGDAQGI 2948

Query: 2961 SGEGSR-------------------LFKIMAKS-FSKRWQSGEITNFQYLMHLNTLAGRG 3000
            +G  +                       I  KS  + +WQ G+I+NFQYLMHLNTLAGR 
Sbjct: 2949 TGGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLKWQQGQISNFQYLMHLNTLAGRS 3008

Query: 3001 YSDLTQYPVFPWVLADYESDTLDLRNPQTFRKLDKPMGCQTEGGEEEFRKRYDSWDDPE- 3059
            Y+DLTQYPVFPWVL+DYES+ LD+ +P+ +R L KPMG   E   ++FR+R+++WDD E 
Sbjct: 3009 YNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPMGALEESRAQKFRERFENWDDQEP 3068

Query: 3060 ------VPKFHYGSHYSSAGIVLFYLLRLPPFSMENQKLQGGQFDHADRLFNSVKDTWVS 3113
                  VPKFHYG+HYSSA IVL+YL+RL PF+    KLQGG++D  DRLF+S+ + W S
Sbjct: 3069 NEHGHKVPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQPDRLFSSITEAWAS 3128

Query: 3114 AAGKSNTSDVKELIPEFYYLPEFLENQFNLDLGEKQSGEKVGDVVLPPWAKGSSREFIRK 3173
            ++ + +T  V ELIPEFYYL EFL N    + G KQ GE + D++LPPWAKGS +EFI+ 
Sbjct: 3129 SS-QGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIILPPWAKGSPQEFIKL 3187

Query: 3174 HREALESDYVSENLHHWIDLIFGYKQRGKAAEDAVNVFYHYTYEGNVDIDSVSDPTMKAS 3233
            HR+ALESDYVSE+LH WIDLIFGY+Q+GKAA+D++NVFY+ TYEG V+ID++SDP  KA+
Sbjct: 3188 HRKALESDYVSEHLHEWIDLIFGYRQQGKAADDSLNVFYYLTYEGAVNIDAISDPVEKAA 3247

Query: 3234 ILAQINHFGQTPKQLFQKPHPQRRTDRKVLPHPLRYSAYLTHQEIRKTTSSVSQIVTYND 3293
             +AQIN+FGQTPKQLF KPHP+R      LP    Y+  LT   I+     V QI   ND
Sbjct: 3248 TIAQINNFGQTPKQLFDKPHPKRNATLMGLPF---YAKALTGNFIKDIGEPVGQIRLIND 3304

Query: 3294 KILIAAANSFLKPVNYSEYISWGFPDRSLRILTYDQDKLVSTHENLHGGSQIQCTGVSHD 3353
            +      N  L P N+S+Y+ WG PD S+R  T D+ K++  H   H G  + C   + D
Sbjct: 3305 RATCVGFNKVLLPPNHSKYMLWGLPDGSIRYNTGDKIKVLEDH---HDGP-LTCLTATED 3360

Query: 3354 GNILTTGGDDGVVAVWRFFKDGTRRLLRMEKALCAHTAKITCIYVSQPYSLIVSGSDDCS 3413
            G I  +GG D ++ V+        +   + K L  HT  ITC+  S+PYS+IVSGSDD +
Sbjct: 3361 GRICVSGGSDSLICVYNL------KRFSLAKRLSGHTGSITCVSASRPYSIIVSGSDDRT 3414

Query: 3414 VILWDLTSLAFVKQLPRFPASVSALHVNNLTGEILTGAGVLFAVWSVNGDCLAVVNTSQL 3473
             I+WDL  L +V+ L      +S + +++ TGEI+  +G   +V++VNG+ L    TSQ+
Sbjct: 3415 CIIWDLNRLCYVRSLDAHEGPISCIGIHDTTGEIVVCSGTTISVYTVNGELLINYKTSQI 3474

Query: 3474 PSDLILSVASTTNSDWQDTNWYVTGHQSGAVKVWKM------------VHYTSDEAANSK 3521
             +D I     +   +W   N  +TGH+ G VKVW +             +  ++   N+ 
Sbjct: 3475 ANDQITCCIWSKGPEWLGENVLLTGHRDGKVKVWGLETRLLPDNNNSNNNNNNNNNNNNN 3534

Query: 3522 SKSPPSTLGGMSLNGQTQEYR--LLLQKVL---KAHKHPVTALCLPPDLKQLLSGDASGH 3576
            +   PST      N    +++  ++L+      ++H   +T++ L  D ++  +GD +G 
Sbjct: 3535 ATQIPST------NNNKLKFKNVIILRATFSNSQSHSTAITSIFLTNDQQKFYTGDITGR 3588

Query: 3577 LFSWS 3581
            +  WS
Sbjct: 3589 VCMWS 3593



 Score =  122 bits (307), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 177/848 (20%), Positives = 326/848 (38%), Gaps = 126/848 (14%)

Query: 705  DCLFYLLKRAEPNQQTFRSSNGVNTILPFLVSESHRSGVLRLLSCLIIEDSLQAHPEEIG 764
            D LF L+     N    RS +  N +L FL   S R   LR+L  LI  D  +   +E  
Sbjct: 730  DSLFILISENPDNISLIRSFSIFNILLRFLPYSSVRGKSLRILQQLIKYDP-EPTQKEFD 788

Query: 765  SLIEILKSGMVSTSSGSQQKLDNDAKCDTFGALWRILGANSSAQRIFGEATGFSLLLTTL 824
             LI++L S           K +   K D   A  ++   +  A+  F E  GF  +++  
Sbjct: 789  GLIKVLTS---------VNKENYPMKSDILNATRKLFNISKHARDSFREHGGFVSIISVF 839

Query: 825  HSFQNDXXXXXXXXXX--XXHMKIFGFLMRAMTAAVYSNPVNRIRLHTILSSNTFYDLLS 882
             S ++                +++   + R  T+A+  N +NR      +   TF   L 
Sbjct: 840  ISLESSFSPNRKDSRNWDMEKLELIESICRCTTSALCGNVINRENFEQQIGYKTFSSCLI 899

Query: 883  ESGLLCVDCEKHVIXXXXXXXXXXXXPPTSNLQVESISSENPEDESGFLSATSFGLSRLD 942
             +G+L  +  K V+                   +  + +EN       L+A+     ++ 
Sbjct: 900  MTGVLGTEFSKSVVDF-----------------IFDMVTEN-------LNASD----QIS 931

Query: 943  KERIYNASAVVVLIRSLL--VFTPKVQLELLRFIEKLANAGPFNQENLTSVGCVGLLLET 1000
             + I N      +I  ++  +     +L+++  I K+A  G +NQE L+ +     +L  
Sbjct: 932  NQMIINNVESFNVILDIIPHIENKDFRLQIISRINKMAEYGRYNQEALSKLSIPDWILSR 991

Query: 1001 INPFLEGSS-PILNHALRIVEVLGAYXXXXXXXXXXXXYILQLKVKCSGHLFVNMMDKLI 1059
                L  ++ P+    L +++ +GA             ++  L+ + S  + + ++  + 
Sbjct: 992  FPSNLSNANDPLQPLLLSLIQTVGA---NCLSGSELRQFVKLLQPEHSPEVLLKILSSMA 1048

Query: 1060 QIEDVRQGSISLAPFIELDMSKAGHSSIQVSLGERTWPPVSGYSFVCWFQFQNFFRSHPK 1119
            +       S    P+ E ++SK     I+V + ER WPP +GY+ + W     F   +  
Sbjct: 1049 K-------SPPTPPYFEFNLSKIPFGYIRVPITERAWPPTNGYTIMFWLYIDKFPTVNNN 1101

Query: 1120 EAEKTSKGSYSKRNGQVMRIFSVGAVDDANTLY-------AELYLH-DNGVFTIATSNSS 1171
                 S  + +  N       +    D  + ++       + LY++  NG+ T+   NSS
Sbjct: 1102 NNNNNSSNNSNNSNNSNNNNNNNNNNDQIDLVHIYSDDKKSSLYIYLKNGIITVNIINSS 1161

Query: 1172 S--LSFPGIEMEEGKWHHLAVVHSKPNALAGLFQSSVASLYLDGKLRHTGKLGYSPSPF- 1228
               +  P  +  EGKW+H+ +VH++      L   +   L++DG L++T      P+   
Sbjct: 1162 KYVIEIPSYKFVEGKWYHIGIVHAR-----RLLGGTDFKLFVDGFLKYTATKAQYPAQIT 1216

Query: 1229 -GKSLQVTLGTPAIRAKVSDLSWRLRCCYLFEEVLTPGSICFMYILGQGYRGLFQDTDLL 1287
             G  L   +G        +D  WR+   YL E+ L    I  +Y LG  Y   F+     
Sbjct: 1217 SGSMLICDIGVSNQNRFPTDSIWRIGTFYLLEDSLGAKHINTIYFLGPNYASNFKG---- 1272

Query: 1288 RFVP----NWACGGEVMAILDSLELEVIAPSGSQRVDSAMKQ--------GNSRL----E 1331
            RF P           +MAI D    + + P    +V   + +         +++L     
Sbjct: 1273 RFSPYQTYEIVNSANLMAIKDLDYGDQLGPLNLAKVSMQIDENKILVGLCASNKLIRTNN 1332

Query: 1332 SSGIVWDMERLRNLSLQLSGK-----KLIFAFDGTSSD-------------------AFR 1367
            SS +V++ E    +  +LS        +  + +GTS +                      
Sbjct: 1333 SSKVVYN-EIFNGIINELSQNHGVALNVFSSPNGTSPNLTGLQNNNNNNNNSGGSNSKKD 1391

Query: 1368 ASGTLSLLNLVDPTSAAASPIGGIPRYGRLSGDVYVCNQCTIGDTVQTVGGIPVVLALVE 1427
              G + ++N  D T+            G L G V    +  + D+++ +GG+P+ L L+E
Sbjct: 1392 LEGRVEIINQADLTTKLR---------GVLIGSVEAFRRNKVADSIKKIGGMPISLLLLE 1442

Query: 1428 AAETRDXXXXXXXXXXXXXXXXXQNVKDMQSLRGYHLLALFLHRRMS--LFDMQSLDIFF 1485
             A + +                  N  +M  + GY LLA  L ++ S  LF+   L++ F
Sbjct: 1443 KANSEETLFDSLGLLVGLIQYHPTNTHEMSQINGYELLAWVLKKKASLGLFNSNILELLF 1502

Query: 1486 RIAACGAS 1493
             +     +
Sbjct: 1503 DLIGINGN 1510



 Score = 67.8 bits (164), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 92/458 (20%), Positives = 175/458 (38%), Gaps = 78/458 (17%)

Query: 2176 VLDFIAQILADIISEQLKATLFIESILECVPLFVDIDSALVFQGLCLSRLMNFXXXXXXX 2235
            V+ F+ QI+   + +  KA   IE +LE  P     +  +++    L  LM         
Sbjct: 2129 VVKFLCQIMLSAMRKTSKAISIIEMVLEGAPTTATDEEFILYHSRILLDLM-----YVVE 2183

Query: 2236 XXXXXXXXXXXSRWSANLDPLCWMIVDRVYMGCFPTPVGVLRTLEFLMSMLQLSNKDGRI 2295
                        R  +NL  L  M+VDRV +        ++      + ++++  K    
Sbjct: 2184 TNITKTEFFDNERVHSNLIKLSSMLVDRVNLDQLVKNNKIIIAKRIFLFIVKILEK---- 2239

Query: 2296 EDAVPSGKGILSIARGGRQLDPYIHAILKNTNRMVMYCFLPTFLKNMGEDDLLANLAFLT 2355
                      L   R G  L   + ++ K+ NR+++Y      L N   D          
Sbjct: 2240 ----------LEADRVG--LQKTVQSLYKSLNRIILY------LINHTTD---------- 2271

Query: 2356 ETGRSLGIFKPSQEDYTVDICTVLQLLIANKRLVLCPSNVDNDLMCCFCINLMALLRDKR 2415
                              D+  V   +I ++R++   +N+D+D M  FC  L  L+   +
Sbjct: 2272 -----------------TDLSFVANHIINHQRIIFSENNLDSDFMNAFCYPLYKLVISDQ 2314

Query: 2416 LTAQNLAVDLLKYLV-------VHRRPSLEDLLVSKPNQGQQMDI--LHGGLDKLLTGST 2466
                + ++ L + L+       +    ++  L VS  +  +Q +I  L  G + L   S 
Sbjct: 2315 HEHVDNSIKLWRLLLSLKTSSYIESLATVLQLKVSSGSNQRQSEIIDLKPGFELLRNTSG 2374

Query: 2467 TAFFE------WLQSSQQTISKVLDQCALIMWVQYITGSAKFPGVR-IKGMEVRRKKDMG 2519
               F       W+  + QTI++V ++      + +     K      +  ++ RR + + 
Sbjct: 2375 NGAFNNDEFKLWINDNIQTITQVFEENPKKQHLSFKNNEKKHSSEHTLPSLKSRRTERLS 2434

Query: 2520 RKLREIAKLDSRHWEQ----INERRYNLDLVRDVMSTELRAIRQDKYGWILHGESEWQSQ 2575
            +K R+  K D  H E+    I ++             +++ +  DK  +      +W++ 
Sbjct: 2435 KKQRQDRK-DQSHQEEKSKHITKKAQYFVRSESDRRKKIKQLESDKQKF---NAIQWENM 2490

Query: 2576 LQQLVHERGIFPVRQLSTEPAWQLCAVEGPYRMRKKLE 2613
              Q+  ER ++   +      W+L + EGPYRMRKK+E
Sbjct: 2491 RAQITRERAVWGPSEPHPLDKWKLDSTEGPYRMRKKME 2528



 Score = 63.9 bits (154), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 37/133 (27%), Positives = 67/133 (50%)

Query: 505 KDLEAIQMLQDIFLKADNLEVQAEVLNRMFKIFSSHLENYKLCQQLRTVPLFILNMGGFP 564
           K+  A ++L+  FLK++  E + ++L+R+  ++SS+  N+ L Q   T+  FI       
Sbjct: 498 KNGNAFKVLERYFLKSNYEENRVKILDRILSVYSSNTVNFILLQHTSTLTKFIQEYESLS 557

Query: 565 PALQEVILKILEYAVTVVNCIPXXXXXXXXXXXXXPISTSLKHTILSFFVKLLSFDQQYK 624
             L+  ++KI+ + VTV+NC+P               S      I      L++F+ +YK
Sbjct: 558 NGLKYHVMKIVCFVVTVLNCVPFQELSTFSLLVGENPSFYTLEMINQLITTLVNFEFRYK 617

Query: 625 KVLREVGVLGALL 637
            + RE G+L  L+
Sbjct: 618 HIFRETGLLDILV 630

 Score =  504 bits (1299), Expect = e-142,   Method: Compositional matrix adjust.
 Identities = 285/726 (39%), Positives = 394/726 (54%), Gaps = 53/726 (7%)

Query: 2897 VHELLKRDYQLRPVAIEIFSMDGCNELLVFHKKEREDVFKNLTAMNLPRNSMLDTTISAS 2956
            + EL +  + L+ +A+EIF  +G ++ LVF+  +R   FK+  +           ++   
Sbjct: 2468 MRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQ--------PSLKGK 2519

Query: 2957 SKQDSGEGSRLFKIMAKSFSKRWQSGEITNFQYLMHLNTLAGRGYSDLTQYPVFPWVLAD 3016
            +  +     R +    +   ++WQ  +I+NF+YLM+LNT AGR  +D  QYPVFPWVLAD
Sbjct: 2520 ATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLAD 2579

Query: 3017 YESDTLDLRNPQTFRKLDKPMGCQTEGGEEEFRKRYDSWDDPE---VPKFHYGSHYSSAG 3073
            Y S+TL+L NP+ FR L KPMG QT+  + +F +R+   +  E     + HY +HYSSA 
Sbjct: 2580 YTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAI 2639

Query: 3074 IVLFYLLRLPPFSMENQKLQGGQFDHADRLFNSVKDTWVSAAGKSNTSDVKELIPEFYYL 3133
            IV  YL+R+PPF+     LQGG FD ADR+F+SVK TW SA+ + N SDV+EL PEF+YL
Sbjct: 2640 IVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESAS-RENMSDVRELTPEFFYL 2698

Query: 3134 PEFLENQFNLDLGEKQSGEKVGDVVLPPWAKGSSREFIRKHREALESDYVSENLHHWIDL 3193
            PEFL N   ++ G  Q G  +GDV LPPWA G  R+FI  HR+ALESD+VS NLHHWIDL
Sbjct: 2699 PEFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDL 2758

Query: 3194 IFGYKQRGKAAEDAVNVFYHYTYEGNVDIDSVSDPTMKASILAQINHFGQTPKQLFQKPH 3253
            IFGYKQ+G AA DAVN+F+ Y Y   +D+ S++DP +K++IL  +++FGQ PKQLF KPH
Sbjct: 2759 IFGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPH 2818

Query: 3254 PQRRTDRKVL--------------PHPLRYS-------------AYLTHQEIRKTTSSVS 3286
            P R    K L              P P  YS              YL          ++ 
Sbjct: 2819 PARTAAGKPLPGKDVSTPVSLPGHPQPFFYSLQSLRPSQVTVKDMYLFSLGSESPKGAIG 2878

Query: 3287 QIVTYNDKILIAAANSFLKPVNYSEYISWGFPDRSLRILTYDQDKLVSTHENLHGGSQIQ 3346
             IV+    IL    N  L P  ++   SWGF D S  + +Y  DK++ T ENL    +  
Sbjct: 2879 HIVSTEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGRCL 2938

Query: 3347 CTGVSHDGNILTTGGDDGVVAVWRF-FKDGTRRLLRMEKALCAHTAKITCIYVSQPYSLI 3405
            C  V      + T G   VV VW      G  R LR+ +AL  HT  +TC+  S  +SL+
Sbjct: 2939 C-AVCPSPTTIVTSGTSTVVCVWELSMTKGRPRGLRLRQALYGHTQAVTCLAASVTFSLL 2997

Query: 3406 VSGSDDCSVILWDLTSLAFVKQLPRFPASVSALHVNNLTGEILTGAGVLFAVWSVNGDCL 3465
            VSGS DC+ ILWDL  L  V +LP     +SA+ +++++G I++ AG   ++W+VNG  L
Sbjct: 2998 VSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNGQPL 3057

Query: 3466 AVVNTSQLPSDLILSVASTTNSDWQDTNWYVTGHQSGAVKVWKMVHYTSDEAANSKSKSP 3525
            A + T+  P   I          W  +   +TG Q G V+VWK              + P
Sbjct: 3058 ASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSVPGRPAGEEP 3117

Query: 3526 PSTLGGMSLNGQTQEYRLLLQKVL---------KAHKHP-VTALCLPPDLKQLLSGDASG 3575
            P+     S  G   E  L L + L          +   P VTAL +  +  +LL GD  G
Sbjct: 3118 PAQ--PPSPRGHKWEKNLALSRELDVSIALTGKPSKTSPAVTALAVSRNHTKLLVGDERG 3175

Query: 3576 HLFSWS 3581
             +F WS
Sbjct: 3176 RIFCWS 3181



 Score = 65.1 bits (157), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 102/462 (22%), Positives = 166/462 (35%), Gaps = 75/462 (16%)

Query: 1070 SLAP-FIELDMSKAGHSSI---------------QVSLG-----ERTWPPVSGYSFVCWF 1108
            +LAP F+E DMS  G+  +                VS G      R +PP  G +F CWF
Sbjct: 1017 ALAPSFVEFDMSVEGYGCLFIPTLSTVMGTSTEYSVSGGIGTGATRPFPPPGGLTFSCWF 1076

Query: 1109 QFQNF---FRSHPKEAEKTSKGSYSKRNGQVMRIFSVGAVDDANTLYAELYLHDNGVFTI 1165
                       HP       +  +  R  Q    FSV    D  +L       +     +
Sbjct: 1077 LISRHGAATEGHPLRFLTLVR--HLARTEQPFVCFSVSLCPDDLSLVVSTEEKEFQPLDV 1134

Query: 1166 ATSNSSSLSFPGIEMEE--------GKWHHLAVVHSKPNALAGLFQSSVASLYLDGKLRH 1217
                  S    G +++         G+WHHLAVV +K      + +    S  LDG++  
Sbjct: 1135 MEPEDDSEPSAGCQLQVRCGQLLACGQWHHLAVVVTKE-----MKRHCTVSTCLDGQVIG 1189

Query: 1218 TGKLGYS---PSPFGK-------SLQVTLGTPAIRAKVSDLSWRLRCCYLFEEVLTPGSI 1267
            + K+ Y    P PF          +   + TP +  + S L WRL   YLFEE ++  ++
Sbjct: 1190 SAKMLYIQALPGPFLSMDPSAFVDVYGYIATPRVWKQKSSLIWRLGPTYLFEEAISMETL 1249

Query: 1268 CFMYILGQGYRGLFQDTDLLRFVPNWACGGEVMAILDSLELEVIAPSGSQRVDSAMKQGN 1327
              +  LG  Y G FQ                V    + L+ E       +RV   +   +
Sbjct: 1250 EVINKLGPRYCGNFQ---------------AVHVQGEDLDSEATPFVAEERVSFGLHIAS 1294

Query: 1328 SRLESSGIVWDMERLRNLSLQLSGKKLIFAFDGTSSDAFRASGTLSLLNLVDPTSAAASP 1387
            S + S      +  +RN   ++  + +    + +S D   A     L N     S +   
Sbjct: 1295 SSITS------VADIRNAYNEVDSRLIAKEMNISSRD--NAMPVFLLRNCAGHLSGSLRT 1346

Query: 1388 IGGIPRYGRLSGDVYVCNQCTIGDTVQTVGGIPVVLALVEAAETRDXXXXXXXXXXXXXX 1447
            IG +   G+L   V V +      ++  +GG  ++L L+  A                  
Sbjct: 1347 IGAV-AVGQLG--VRVFHSSPAASSLDFIGGPAILLGLISLATDDHTMYAAVKVLHSVLT 1403

Query: 1448 XXXQNVKDMQSLRGYHLLALFLHRRMSLFDMQSLDIFFRIAA 1489
                    MQ + GY ++A  L ++ SL + +   +   +A 
Sbjct: 1404 SNAMCDFLMQHICGYQIMAFLLRKKASLLNHRIFQLILSVAG 1445

 Score =  454 bits (1167), Expect = e-126,   Method: Compositional matrix adjust.
 Identities = 279/728 (38%), Positives = 385/728 (52%), Gaps = 100/728 (13%)

Query: 2892 WKLDSVHELLKRDYQLRPVAIEIFSMDGC---NELLVFHKKEREDVFKNLTAMNLPRNSM 2948
            W  D + E+ KR + L+  AIEIF   G      L  F+K    D+  +L  M+ P  + 
Sbjct: 3428 WSYDDIIEIHKRRHVLKNNAIEIFLGSGVPHKTYLFAFNKPSDRDIVYDLI-MSKPLPNR 3486

Query: 2949 LDTTISASSKQDSGEGSRLFKIMAKSFSKRWQSGEITNFQYLMHLNTLAGRGYSDLTQYP 3008
            +D                   I+  S +K+WQSG I+NF+YLMHLNTLAGR ++DLTQYP
Sbjct: 3487 VDYAAEVHGN-----------ILKMSITKKWQSGLISNFEYLMHLNTLAGRSFNDLTQYP 3535

Query: 3009 VFPWVLADYESDTLDLRNPQTFRKLDKPMGCQTEGGEEEFRKRYDSWDDPEVPKFHYGSH 3068
            +FP++L DYES+ LDL NP TFR   KPMG Q     E+F ++Y+   +     +HYGSH
Sbjct: 3536 IFPFILRDYESEVLDLENPNTFRDFTKPMGAQDPKRLEKFIEKYNDLLEMNEKPYHYGSH 3595

Query: 3069 YSSAGIVLFYLLRLPPFSMENQKLQGGQFDHADRLFNSVKDTWVSAAGKSNTSDVKELIP 3128
            YS+ G VL +L+RL PF+      QGG+FD  DR F+S+  +W  ++  SN SDVKELIP
Sbjct: 3596 YSNIGSVLHFLVRLQPFTSYFIDFQGGRFDVPDRAFHSIAQSWNLSSSISN-SDVKELIP 3654

Query: 3129 EFYYLPEFLENQFNLDLGEKQSGEKVGDVVLPPWAKGSSREFIRKHREALESDYVSENLH 3188
            EF+YL +FL N     +G KQ+G KV DV+LPPWA    R FI+KH EALE  YVSENLH
Sbjct: 3655 EFFYLSDFLVNSNKFFMGIKQNGVKVDDVILPPWAHNDPRLFIKKHNEALECKYVSENLH 3714

Query: 3189 HWIDLIFGYKQRGKAAEDAVNVFYHYTYEGNVDIDSVSDPTMKASILAQINHFGQTPKQL 3248
            HWIDL+FGYKQ+G+AA  A N+F+  TYEG VDIDS+ D   + + +AQI+ +GQTPKQ+
Sbjct: 3715 HWIDLLFGYKQQGEAAVKAHNMFFPLTYEGAVDIDSIEDQLNRDAAVAQIHSYGQTPKQI 3774

Query: 3249 FQKPHPQ-------RRTDRKVLPHPLRYSAYLTHQEIRKTTSSVSQIVTYNDK--ILIAA 3299
            F KPHP+       R T   +   P R ++Y+  Q      S +  I   ND   I +  
Sbjct: 3775 FTKPHPKKNWSKTIRLTQDSIFTKPERLTSYIMFQ----YRSPIGSITIANDSSPIHLTP 3830

Query: 3300 ANSFLKPVNYSEYISWGFPDRSLRILTYDQDKLVSTHENLHGGSQIQCTGVSHDGNILTT 3359
                  P N ++ ISWG  D++LR+ + D  K++S  E L+    I C  ++ +G +  T
Sbjct: 3831 QRILFFPDN-NKSISWGHWDQNLRVNSIDTGKVLSIIEVLN--DDIICGDITKNGRLFVT 3887

Query: 3360 GGDDGVVAVWRFFKDGTRRLLRMEKA--------LCAHTAKITCIYVSQPYSLIVSGSDD 3411
            GG  G V VW+   +    + R E+         L  HT  I C+ VSQ YS+IVSGS D
Sbjct: 3888 GGTAGTVKVWKRCNNDGTIMTRKERGDNLSLWSTLYGHTNSILCVTVSQEYSIIVSGSKD 3947

Query: 3412 CSVILWDLTSLAFVKQLPR------------------FPASVSALHVNNLTG------EI 3447
             + I+WDL  L ++  L                    F  ++     NN  G        
Sbjct: 3948 SNCIIWDLNRLTYINSLQHDHPVTCVQVSPTFGYIATFETNIYNKQNNNSGGGGSKNDNS 4007

Query: 3448 LTGAGVLFAVWSVNGDCLAVVNTSQLPSDLILSVASTTNSDWQDTNWYVTGHQSGAVKVW 3507
            + G+G L  +WS+NG  LA  N     +D +  +  T+     +TN  +TG +SG + +W
Sbjct: 4008 INGSGCL-RLWSINGTLLAKQN---FVNDRVNCMIFTSTIQGVNTNLLITGMESGTIILW 4063

Query: 3508 KMVHYTSDEAANSKSKSPPSTLGGMSLNGQTQEYRLLLQKVLKAHKHPVTALCLPPDLKQ 3567
                     A N                   Q+ R L+       K  +TAL +  D  Q
Sbjct: 4064 --------NAWN------------------LQKIRTLVS------KSTITALAVSKDNTQ 4091

Query: 3568 LLSGDASG 3575
            L+SGD +G
Sbjct: 4092 LISGDING 4099