Query: CNT0033387
Subject: sp|Q6ZS30|NBEL1_HUMAN Neurobeachin-like protein 1 OS=Homo sapiensOS=Dictyostelium discoideum GN=lvsC PE=3 SV=2
Score = 605 bits (1560), Expect = e-174, Method: Compositional matrix adjust.
Identities = 324/744 (43%), Positives = 444/744 (59%), Gaps = 60/744 (8%)
Query: 2667 RWDLSQVKAVHSTRYLLQYSALEXXXXXXXXXXXXXXXXQRLAKDIGVMIVDLHNGRGSG 2726
RW +K VH RYLL+ SA+E +R ++N S
Sbjct: 1770 RWPNEMIKDVHLRRYLLRGSAIEIFMRDKTNYLFNFKKNER---------NKVYNKINSV 1820
Query: 2727 KSTRGKEHIIDYIDRRKACELAEDARKQWRRREMSNFDYLVTLNTLAGRSYNDMTQYPVF 2786
K KE + ++ + A +W+ R +SNFDYL+TLNT+AGR+YND+TQYPVF
Sbjct: 1821 KREFSKEPTLS------PSDMLKKATSEWQARRISNFDYLMTLNTIAGRTYNDLTQYPVF 1874
Query: 2787 PWILSDYTSEKLDLSDHASFRDLSKPVGALNQKRFELFEERFQNFTDPDIPSFYYGSHYS 2846
PW+++DYTS LDL+ +FRDLSKP+GALN+KR E+F++R+++F DP IP FYYGSHYS
Sbjct: 1875 PWVIADYTSPVLDLNKAETFRDLSKPIGALNEKRLEIFKDRYESFDDPVIPKFYYGSHYS 1934
Query: 2847 SMGIVLFYLLRLEPFTLLHRQLQGGKLDHADRLFHSVESAFQNCLTNSGDVKELVPEFFY 2906
S GIVLFYL+RLEPFT LQGG+ DH DR+F S+ A+ N LT+S DVKEL+PEF+Y
Sbjct: 1935 SAGIVLFYLIRLEPFTTQFLNLQGGRFDHPDRMFDSIALAWDNSLTSSTDVKELIPEFYY 1994
Query: 2907 LPEFLVNSNGYYLGVKQDGEALGDIVLPPWAKRSPELFIQLNREALESEYVSDHIHEWID 2966
+PEFL N N G+KQ+G + D++LPPWA SP FI++NREALES+YVS H+HEWID
Sbjct: 1995 MPEFLTNHNHINFGIKQNGIGIEDVLLPPWAS-SPSDFIRINREALESDYVSSHLHEWID 2053
Query: 2967 LMFGYKQRGRPAVEAANVFYHLTYEGAVDLDAMEDCTERTAIEDQIAGFGQTPIQLFKKK 3026
L+FG KQRG+ A E NVFY+LTYEG+VD+D++ED T R A E QI FGQTP QLF KK
Sbjct: 2054 LIFGIKQRGKQAKEVFNVFYYLTYEGSVDIDSIEDETTRRATESQINNFGQTPTQLFSKK 2113
Query: 3027 HP-RRGPAQPIARPLYYAPAS------ITMTSTIP-----APSPSPGQKVTKVVFVGLID 3074
H +R P + P + + +T+ P P P+P + L+
Sbjct: 2114 HHIQRDPLNESHISILKTPPNQLQAYFLKITNKNPIVYVYIPEPNP-------IMSYLVA 2166
Query: 3075 GLVVTINKSLSVVVRTWITPALQNFTFSSSQDSYFGISQEVVLSRKIYGPIVDDVSLSSC 3134
V I+KS + W P+ N S F + R+I P +DV++S
Sbjct: 2167 DKVTVIDKSRTTTNHKWF-PSTPNDKISPFT---FELDPSSTTKRRIGLPFANDVTISPN 2222
Query: 3135 CFGTLLVRSSSFLLTCGHWDNSFKVISLDGGDLVQSNSQHKDVVTSLSVAVDGSVVVTGS 3194
CF + ++++C HWDNSFK+ +D L+QS +HKD VT LS+A DG ++TGS
Sbjct: 2223 CFA--ITSDGRYVISCAHWDNSFKLSFVDSAKLIQSVVKHKDTVTCLSLASDGQTLITGS 2280
Query: 3195 RDTTVMVWDIEHTTVSTRRLGSIKDTLTEKHRKSDTVVISDKPRHVLCGHDDAITSVAVR 3254
+DTTVMVW I +T + G+ K +D P H+L GHDD IT V V
Sbjct: 2281 KDTTVMVWRI----ATTNKSGAPK--------------FNDVPDHILYGHDDEITCVDVN 2322
Query: 3255 VELDIVVSGSKDSTCIFHTLRTGRYVRSIRHPNRCPVTNLKVSQHGLVVVYSHGDLSLHV 3314
V LDI +SGSKD TCI H L+ G YVRSI P + P++ + +S G +V+YS DL +++
Sbjct: 2323 VGLDISISGSKDGTCIIHNLKHGEYVRSIYLPRQSPISLIAISNQGYIVIYSQADLMIYL 2382
Query: 3315 CSINGKWLASVDVKGRLNCMDISHCGHFLVCGGDQGQVLVFKLQTLEVVRRYEGAGVAVT 3374
SING L +VD RL+ + IS +L+ GG++G V++ L L+ G +
Sbjct: 2383 YSINGGLLKTVDTHERLHSIIISKDSEYLITGGERGVVVIRTLFNLKPTNHKLVFGTPIH 2442
Query: 3375 SLTV-TPEDCFLVGTHDGALVVFS 3397
SL + + + +VG DG L++ +
Sbjct: 2443 SLAMASDQKHLMVGLEDGRLLIIA 2466
Score = 304 bits (779), Expect = 3e-81, Method: Compositional matrix adjust.
Identities = 229/833 (27%), Positives = 386/833 (46%), Gaps = 65/833 (7%)
Query: 952 LLRGMREVLETDLTHYQALFRDGECFVHIVTLLNEERPAEVGSQLSLDVLFTLTRLLQGN 1011
+L G+R++++ + Q LF+ F+ IV L+N + E S L VL T+ L+ N
Sbjct: 1 MLDGIRQIIKNN-PKKQNLFKKFRVFIKIVNLVNADDKKERLSVLCHSVLRTVILLMANN 59
Query: 1012 EASKASFRSIVGAGYKTLEFVLIELHNGKPSREXXXXXXXXXVDGSFD-PSNMLIQNEDV 1070
K FR+ +G Y T++ ++I+ G S VDG FD +IQN D
Sbjct: 60 PKIKKHFRNHIG--YDTIKDLIIK-SEGIVSETTMNILFDMIVDGEFDIEYKYVIQNPDS 116
Query: 1071 VLLYFSILQRCNEQDRVNGLDTFQLLLEESTANRAACVRAGLLSLLLEWFAKETDVALIV 1130
LL F++L+ + + LD F +++E+ T N++ C L+ LLE K + +
Sbjct: 117 CLLIFNLLKYFPTKLQHEILDRFTVMVEKCTTNQSVCCNCHLIYNLLEAIYKGQPMEVTT 176
Query: 1131 KFGRLMQMIGGHSISGKDMRSIFALLRSSKDGLRPRHGTLLLQIFQGML--KEQGPAVFF 1188
K +L++ +G HS++ ++++ +F LL+S + P + LL Q + + GP V+F
Sbjct: 177 KILKLIERLGIHSVTVRELKKLFGLLKSEQGDYLPPTTSALLTTLQNISNSRNPGPQVYF 236
Query: 1189 DLSGRDSGIVVTSPLRWPSNRGFSFCAWARVESF--PAGSSPKAPEGMMGLFSFLSENGK 1246
D G+DS I++ + +WP +GFSFC W R+ESF P G+ PE LFSFLS++G
Sbjct: 237 DFDGKDSCIILPTFDKWPFPKGFSFCTWVRIESFVDPTGT----PEYKPRLFSFLSDSGC 292
Query: 1247 GCSATISSEQFVVESISNKRQITSLKV--QLQTKRWYHICVTHNTQRALSGGNTIKVYID 1304
G +Q V +++N + + + WY + V ++ L N I++YI+
Sbjct: 293 GIEVLFIYQQLQVLTVNNHQSKAVFQSPPTFVEREWYFVSVVYSIN--LISSNEIRIYIN 350
Query: 1305 GELVASDRFRYPKVGEMLTRCTIGASAPITTVDVIGFNKISGGFSAPFCGQLGPLYLFDD 1364
G+ A + G + IG ++ K+SG P GQ+G +FD+
Sbjct: 351 GQQSAKSSIKLNISGTLWNHFKIGNNS----------KKMSGERECPLYGQMGAFNIFDE 400
Query: 1365 AMSAEQAMGVFSLGPDYMYSFLPSEVGYVPENISTDSIINDKDGLAFKMVFGYNAQASSG 1424
++S Q +++LGP++ SF E ST S + L + YN +A G
Sbjct: 401 SLSPSQIQAIYTLGPNFNTSFQDVEG-------STKSAHTFESSLTSHLFLNYNCRALDG 453
Query: 1425 RALFDISPVLEYSPDPILYDATIMSGTLLCYRHLVQDSVQCVGGIGVFFPLLTQLDQPVC 1484
D +P + + YDAT++S C ++D + C+GGI V FPL+ Q++ P+
Sbjct: 454 DLCLDNTPDIGGDKN---YDATLVSIN-PCVSRDIKDIIYCLGGIKVLFPLIQQINNPIS 509
Query: 1485 TAS---------------DVMGNTSDQKYVEGYPIDSHVAVEVIDLLTAVLDGNLANQQY 1529
S + + I+ + +V+ L +L + ANQ+
Sbjct: 510 PLSLELITNENNNNNNNNLSLSSQQQTLEQLQQSINIKLTNQVLALFKFMLKESEANQEE 569
Query: 1530 MRNMSGMSILGFLLQSVSPQHLTVDVVAALERLVTTXXXXXXXXXXXXXXXEALVKLYFN 1589
M G S++G+LLQ +SP++LT+ + E L N
Sbjct: 570 MLRCQGFSVMGYLLQQISPEYLTIGCTNIFIDM-------SNQISDPTLVEEVYSNLMLN 622
Query: 1590 PHIWIFTPLIVHRELYVSLINYFKKDGSLLRSVCGLPRVLDMLRQFYW-DKPKRKALGTK 1648
IWI T + R L V + + + + + +LD++ FYW D K +A
Sbjct: 623 FCIWIKTKYELQRNLLVIIKQIVFEKYDQVSDIITVQLILDIMNDFYWYDDSKNEAHRNH 682
Query: 1649 PLLHPVTKAVIGERPNRSEISELRQLVLILAEGGLREKASLVDIKALVAFLEASEDDICV 1708
H K ++ +RP+ S I ELRQ++ + LR + S DI+A++ FL +D +
Sbjct: 683 ---HFFNKDILSKRPSISNIRELRQILFEVLRILLRHQKS-TDIQAIIKFLIYCKDYQQL 738
Query: 1709 KDVLFMVLSLLTQKSFVASFIEHVNSLGGITILLNLIRRPQEDIRLLAFRLIG 1761
+++ VL L F + + LGG + L L++ E +R A +LI
Sbjct: 739 IEMMEFVLGLNGNGHNCQQFFDEIMGLGGTDVFLTLLKIDDEGVRNTAIQLIS 791
Score = 63.2 bits (152), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 45/139 (32%), Positives = 72/139 (51%), Gaps = 12/139 (8%)
Query: 2332 EAKHLKSTTSQRIQDVEALLSELDDANLAESQQKTALEDQSHVALGTI---CSVDRCRQT 2388
E K L S +R + + ++ D+ E++ A E ++ L +I + C +
Sbjct: 1490 EEKSLYSWLEKRKKKLTKVVLNTDEK---EAESFNAAERKADNDLNSIHVKLWMPECERR 1546
Query: 2389 AAQLAYDEE-QQAISEQWCHMFRYLTDERGPWSTVPFPNDVTLHWKLDKMEDPVRRRLKL 2447
A L E + + QW + R LT+ERGPW T + +HWKLDK E+ R R+KL
Sbjct: 1547 ALHLYKARELRNQTTVQWRKILRSLTNERGPWGTT----ESIVHWKLDKTENSSRMRIKL 1602
Query: 2448 RRNYHFNKEYLHPATSISK 2466
+RNY F+ E+L+ A + S+
Sbjct: 1603 KRNYKFD-EHLNCAINDSE 1620
Query: CNT0033387
Subject: sp|P50851|LRBA_HUMAN Lipopolysaccharide-responsive and beige-likeGN=NBEAL1 PE=2 SV=3
Score = 508 bits (1308), Expect = e-143, Method: Compositional matrix adjust.
Identities = 356/1046 (34%), Positives = 515/1046 (49%), Gaps = 206/1046 (19%)
Query: 2397 EQQAISEQWCHMFRYLTDERGPWSTVPFPNDVTLHWKLDKMEDPVRRRLKLRRNYHFNKE 2456
+Q A +W + YLT ERGPW+ +HWKL +E+ R RLKL NY+F
Sbjct: 1767 QQLATLRRWKAIQLYLTCERGPWAK---RKQNPIHWKLANVENYSRMRLKLVPNYNFKTH 1823
Query: 2457 YLHPATSISKGPPVDLVNERGSSVELLMGGVRQFLLKGMRGVTEESLSDGEDNQLKSNDV 2516
A + G + + + SS LL+ V+Q +SD +++L +
Sbjct: 1824 EEASALRDNLG----IQHSQPSSDTLLLEVVKQV-----------KVSDMVEDKLDLPEE 1868
Query: 2517 EVTPAEADVDSSRRSEETGVAAGVTEEGGTLQEHVQVALPEEAGEEEVLLSVSCIMVSAK 2576
++T A +VD E+ +E+++L C +++
Sbjct: 1869 DIT-ARVNVDEKE---------------------------EQDQKEKLVLMEDCELITII 1900
Query: 2577 RKVAGRLEVMQSSLHFYGEFIVEGTGGRSVFNNAGGLNYPDAVTMEKGFNKSKMSGRRDF 2636
+ GRLE+ ++FY G + D V GF DF
Sbjct: 1901 DVIPGRLEITTQHIYFYD----------------GSIEKEDGV----GF---------DF 1931
Query: 2637 LDGSEVDRGNAMERLDPMQGGLVKGIKRHSRWDLSQVKAVHSTRYLLQYSALEXXXXXXX 2696
+W SQ++ +H RY L+ SALE
Sbjct: 1932 ------------------------------KWPHSQIREIHLRRYNLRRSALEIFHVDQS 1961
Query: 2697 XXXXXXXXXQRLAKDIGVMIVDLHNGRGSGKSTRGKEHIIDYIDRRKACEL--AEDARKQ 2754
R I ++ LH+ Y R EL A ++
Sbjct: 1962 NYFLNFKKEVR--NKIYSRLLSLHSPNS-------------YYGSRSPQELFKASGLTQK 2006
Query: 2755 WRRREMSNFDYLVTLNTLAGRSYNDMTQYPVFPWILSDYTSEKLDLSDHASFRDLSKPVG 2814
W RE+SNFDYL+ +NT+AGR+YND+ QYPVFPWIL DYTSE+LDL++ A FRDLSKP+G
Sbjct: 2007 WVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIG 2066
Query: 2815 ALNQKRFELFEERFQNFTDP--DIPSFYYGSHYSSMGIVLFYLLRLEPFTLLHRQLQGGK 2872
+N+K + E+++NF DP I F+YG+HYS+ V+ YL+R+EPFT LH QLQ G+
Sbjct: 2067 VVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGR 2126
Query: 2873 LDHADRLFHSVESAFQNCLTNSGDVKELVPEFFYLPEFLVNSNGYYLGVKQ-DGEALGDI 2931
D ADR FHS+ + +Q + N DVKEL+PEFFY PEFL N N + LG Q E + D+
Sbjct: 2127 FDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDV 2186
Query: 2932 VLPPWAKRSPELFIQLNREALESEYVSDHIHEWIDLMFGYKQRGRPAVEAANVFYHLTYE 2991
+LP WAK S E FI +R+ALESEYVS H+HEWIDL+FGYKQRG AVEA NVFY+ +YE
Sbjct: 2187 ILPKWAK-SAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYE 2245
Query: 2992 GAVDLDAMEDCTERTAIEDQIAGFGQTPIQLFKKKHPRRGPA-QPIARPLYYAPASITMT 3050
GAVDLDA+ D ER A+E I FGQTP QL K+ HP R A + + +P +++ +
Sbjct: 2246 GAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLF 2305
Query: 3051 STIPAPSPSPGQKVTKVVFV-GLIDG-----------------------LVVTINKSLSV 3086
+P K F+ G+ DG L++TI+ + +
Sbjct: 2306 QHLPE---------LKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVI 2356
Query: 3087 VVRTWITPALQN----FTFSSSQDSYFGISQEVVLSRKIYGPIVDDVSLSSCCFGTLLVR 3142
W+ P +N FTF Q +Q R I G + ++S F ++
Sbjct: 2357 GTHGWL-PYDRNISNYFTFIKDQTVTNPKTQ-----RSINGSFAPGLEITSKLF--VVSH 2408
Query: 3143 SSSFLLTCGHWDNSFKVISLDGGDLVQSNSQHKDVVTSLSVAVDGSVVVTGSRDTTVMVW 3202
+ L + G+WDNS +V+SL G ++ +H D+VT L+ G +++GSRDTT M+W
Sbjct: 2409 DAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIW 2468
Query: 3203 DIEHTTVSTRRLGSIKDTLTEKHRKSDTVVISDKPRHVLCGHDDAITSVAVRVELDIVVS 3262
I T++ G V ++ KP +L GH + + SV + ELD+ VS
Sbjct: 2469 QI------TQQGGV-------------PVGLASKPFQILYGHTNEVLSVGISTELDMAVS 2509
Query: 3263 GSKDSTCIFHTLRTGRYVRSIRHPNRCP----VTNLKVSQHGLVVVYSHGDL-------- 3310
GS+D T I HT++ G+Y+R++R P + NL +S G +VVYS +
Sbjct: 2510 GSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKN 2569
Query: 3311 SLHVCSINGKWLASVDVKGRLNCMDISHCGHFLVCGGDQGQVLVFKLQTLEVVRRYEGAG 3370
+LH+ SINGK+L S +K +++ DI G +V G QG + + L +L +
Sbjct: 2570 ALHLFSINGKYLGSQILKEQVS--DICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMR 2627
Query: 3371 VAVTSLTVTPE-DCFLVGTHDGALVV 3395
+ + + VT E LVG DG L+V
Sbjct: 2628 LPIHCVCVTKEYSHILVGLEDGKLIV 2653
Score = 92.8 bits (229), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 180/865 (20%), Positives = 335/865 (38%), Gaps = 163/865 (18%)
Query: 946 ISIVFDLLRGMREVLE-TDLTHYQALFRDGECFVHIVTLLNEERPAEVG-SQLSLDVLFT 1003
I++ +L + +L+ TD QA+F + CF H++ LL + + L++ +
Sbjct: 323 IALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGQLDCLAISTIQA 382
Query: 1004 LTRLLQGNEASKASFRSIVGAGYKTLEFVLIELHNGKPSREXXXXXXXXXVDGSFDPSNM 1063
LT ++ + A+K F+ +G Y + VL L G+P E V+G +
Sbjct: 383 LTAVMNKSPAAKEVFKERIG--YTHMLEVLKSL--GQPPLELLKELMNMAVEGDHTSVGI 438
Query: 1064 L-IQNEDVVLLYFSILQRCNEQD-RVNGLDTFQLLLEESTANRAACVRAGLLSLLLEWFA 1121
L I N +LL L D ++ D + + + +R CV A + ++E
Sbjct: 439 LGISNVQPLLLLIQWLPELQSHDLQIFISDWLKRICCINRQSRTTCVNANMGIRIIETLD 498
Query: 1122 KETDV------ALIVKFGRLMQMIGGHSISGKDMRSIFALLRSSKDGLRPRHGTLLLQIF 1175
+ + LI G L G S+S +++R + LLR + + T + +
Sbjct: 499 LHSSLHQTCAENLIAIHGSL----GSQSVSSEEIRRLLRLLRVDESESVHPYVTPVTRAI 554
Query: 1176 QGMLKE---QGPAVFFDLSGRDSGIVVTSPLRWPSNRGFSFCAWARVES--FPAGSSPKA 1230
M ++ + +F+LS +GI V +WP + FSF AW ++ G + K
Sbjct: 555 LTMARKLSLESALQYFNLSHSMAGISVPPIQKWPGS-AFSFSAWFCLDQDQLTLGIANKG 613
Query: 1231 PEGMMGLFSFLSENGKGCSATISSEQFVVESISNKRQITSLKVQLQT---KRWYHICVTH 1287
+ L+SF + +G G A I+ +V ++ KR+ ++ + + W++I V H
Sbjct: 614 GKRKQ-LYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITVVH 672
Query: 1288 NTQRALSGGNTIKVYIDGELVASDRFRYPKVGEMLTRCTIGA------------------ 1329
+ G + + +Y +G+ S R+P + E T C IG+
Sbjct: 673 MPGKRPFGQSFVYIYDNGQQKVSAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPF 732
Query: 1330 SAPIT-----------------TVD---------VIGFNKISGGFSAPFCGQLGPLYLFD 1363
S+PIT T++ G G GQLG + +F
Sbjct: 733 SSPITPHRTSFGGILSSASWGGTIEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFY 792
Query: 1364 DAMSAEQAMGVFSLGPDYM--YSFLPSEVGYVPENISTDSIINDKDGLAFKMVFGYNAQA 1421
+ + Q ++ GP+ + + S++ +P NI + Y A+A
Sbjct: 793 EPLQPPQVKALYLAGPNCLSPWKCQESDMADLPGNI----------------LLYYTAKA 836
Query: 1422 SSGRALFDISPVLEYSPDPILYDATIMSGTLLCYRHL---VQDSVQCVGGIGVFFPLLTQ 1478
D+S + G L + + ++D + C+GG+ V FPLL Q
Sbjct: 837 CKNSICLDLS-------------TNCLHGRLTGNKVVNWDIKDIINCIGGLNVLFPLLEQ 883
Query: 1479 LDQPVCTASDVMGNTSDQKYVEGYP----------------------IDSHVAVEVIDLL 1516
+ + G ++K P ++ ++ I ++
Sbjct: 884 I------SHFSEGQIPEEKNESTVPESVTPVEGDWLVWTSTKASESRLERNLVATFILIV 937
Query: 1517 TAVLDGNLANQQYMRNMSGMSILGFLLQSVSPQHLTVDVVAALERLVTTXXXXXXXXXXX 1576
+ + NQ + + G++ LG LLQ V + V+V+ A++ L+
Sbjct: 938 KHFIQRHPINQGNLIHSHGVATLGALLQKVPSTLMDVNVLMAVQLLI----EQVSLEKNM 993
Query: 1577 XXXXEALVKLYFNPHIWIFT--PLIVHRELYVSLINYFKKDGSLLRSVCGLPRVLDMLRQ 1634
+ L F+ IW P + Y+S I K + R G+ +LD LR
Sbjct: 994 QLLQQMYQYLLFDFRIWNRGDFPFRIGHIQYLSTI--IKDSRRVFRKKYGVQFLLDTLRI 1051
Query: 1635 FYWDKPKRKALGTKPLLHPVTKAVIGERPNRSEISELRQLVLILAEGGLREKASLVDIKA 1694
+Y + K L + R R+ + L + L +GG E +I++
Sbjct: 1052 YYGNGCKYNELSLDDI-----------RTIRTSLYGL--IKYFLCKGGSHE-----EIQS 1093
Query: 1695 LVAFLEASEDD---ICVKDVLFMVL 1716
++ ++ A+ ++ + DVLF +L
Sbjct: 1094 IMGYIAATNEEEQLFGILDVLFSLL 1118
Query: CNT0033387
Subject: sp|Q9ESE1|LRBA_MOUSE Lipopolysaccharide-responsive and beige-likeanchor protein OS=Homo sapiens GN=LRBA PE=1 SV=4
Score = 497 bits (1279), Expect = e-140, Method: Compositional matrix adjust.
Identities = 287/778 (36%), Positives = 440/778 (56%), Gaps = 50/778 (6%)
Query: 2641 EVDRGNA-MERLDPMQGGLVKGIKRHSRWDLSQVKAVHSTRYLLQYSALEXXXXXXXXXX 2699
EVD + +++DP +G+ H +W ++++++ S RYLLQ +ALE
Sbjct: 2107 EVDEEDPNFKKIDPKILAYTEGL--HGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVM 2164
Query: 2700 XXXXXXQRLAKDIGVMI-VDLHNGRGSGKSTRGKEHIIDYIDRRKACELAEDARKQWRRR 2758
+ K + + V + G ++ R I R+ + A + ++W+ R
Sbjct: 2165 FNFPDPATVKKVVNYLPRVGVGTSFGLPQTRR-----ISLASPRQLFK-ASNMTQRWQHR 2218
Query: 2759 EMSNFDYLVTLNTLAGRSYNDMTQYPVFPWILSDYTSEKLDLSDHASFRDLSKPVGALNQ 2818
E+SNF+YL+ LNT+AGRSYND+ QYPVFPW++++Y SE+LDL+ +FRDLSKP+GALN
Sbjct: 2219 EISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTNFRDLSKPIGALNP 2278
Query: 2819 KRFELFEERFQNFTDPDIPSFYYGSHYSSMGIVLFYLLRLEPFTLLHRQLQGGKLDHADR 2878
KR F ER++++ D +P F+YG+HYS+ VL +LLR+EPFT LQGGK DHADR
Sbjct: 2279 KRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADR 2338
Query: 2879 LFHSVESAFQNCLTNSGDVKELVPEFFYLPEFLVNSNGYYLGVKQDGEALGDIVLPPWAK 2938
F S+ A++N ++ D+KEL+PEF+YLPE VN N Y LGV DG + D+ LPPWAK
Sbjct: 2339 TFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAK 2398
Query: 2939 RSPELFIQLNREALESEYVSDHIHEWIDLMFGYKQRGRPAVEAANVFYHLTYEGAVDLDA 2998
S E F+ +NR ALESE+VS +H+WIDL+FGYKQ+G AV A NVFY+LTYEGAV+L++
Sbjct: 2399 TSEE-FVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNS 2457
Query: 2999 MEDCTERTAIEDQIAGFGQTPIQLFKKKHPRRGPAQPIARPLYYAPASITMTSTIPAPSP 3058
+ D R A+E QI FGQTP QL + HP RG A ++ ++ A + + PS
Sbjct: 2458 ITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQVSPLMFTDKAQQDVIMVLKFPSN 2517
Query: 3059 SPGQKVTKVVFVGLIDGLVVTINKSLSVVVRTWIT-PALQNFTFSSSQDSYFGISQEV-- 3115
SP V GL V+T+ + V W PA Q + QD + + E+
Sbjct: 2518 SPVTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQ----GAVQDQPYQLPVEIDP 2573
Query: 3116 -------VLSRKIYGPIVDDVSLSSCCFGTLLVRSSSFLLTCGHWDNSFKVISLDGGDLV 3168
+ R+I + + + S CF ++ + ++L CG WD SF+V S D G L+
Sbjct: 2574 LIASNTGMHRRQITDLLDQSIQVHSQCF--VITSDNRYILVCGFWDKSFRVYSTDTGRLI 2631
Query: 3169 QSNSQHKDVVTSLSVA---VDGSV-VVTGSRDTTVMVWDIEHTTVSTRRLGSIKDTLTEK 3224
Q H DVVT L+ + + G+ +++GSRD T+++W + I D
Sbjct: 2632 QVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLW------YWNGKCSGIGD----- 2680
Query: 3225 HRKSDTVVISDKPRHVLCGHDDAITSVAVRVELDIVVSGSKDSTCIFHTLRTGRYVRSIR 3284
+ S+T PR +L GHD +T AV EL +V+SGS++ C+ H++ G +R++
Sbjct: 2681 NPGSETAA----PRAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLIHSM-NGDLLRTLE 2735
Query: 3285 HPNRCPVTNL-KVSQHGLVVVYSHGDLSLHVCSINGKWLASVDVKGRLNCMDISHCGHFL 3343
P C L + S+ G V++ L S+NGK A+++ + + +S G +L
Sbjct: 2736 GPENCLKPKLIQASREGHCVIFYENGL-FCTFSVNGKLQATMETDDNIRAIQLSRDGQYL 2794
Query: 3344 VCGGDQGQVLVFKLQTLEVVRRYEGAGVAVTSLTVT-PEDCFLVGTHDGALVVFSLEF 3400
+ GGD+G V+V ++ L+ + Y G + ++ ++ + C + G G++V+F +F
Sbjct: 2795 LTGGDRGVVVVRQVSDLKQLFAYPGCDAGIRAMALSYDQRCIISGMASGSIVLFYNDF 2852
Score = 190 bits (482), Expect = 2e-46, Method: Compositional matrix adjust.
Identities = 196/903 (21%), Positives = 378/903 (41%), Gaps = 135/903 (14%)
Query: 1054 VDGSFD-PSNMLIQNEDVVLLYFSILQRCNEQDRVNGLDTFQLLLEESTANRAACVRAGL 1112
V G FD N +IQ + + +L++C+ + F +L++S N C GL
Sbjct: 74 VGGQFDLEMNFIIQEGESINCMVDLLEKCDITCQAEVWSMFTAILKKSIRNLQVCTEVGL 133
Query: 1113 LSLLLEWFAKETDVALIVKFGRLMQMIGGHSISGKDMRSIFALLRSSKDGLRPRHGTLLL 1172
+ +L K D + ++ ++ ++++ ++++ F+ L+ K G P H LL
Sbjct: 134 VEKVLGKIEK-VDNMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDK-GRWPPHAGKLL 191
Query: 1173 QIFQGMLKEQGPAVFFDLSGRDSGIVVTSPL-RWPSNRGFSFCAWARVESFPAGSSPKAP 1231
+ + M ++ GP FF+ G+ + + P+ +WP GF+F W R++ ++
Sbjct: 192 SVLKHMPQKYGPDAFFNFPGKSAAAIALPPIAKWPYQNGFTFHTWLRMDPV---NNINVD 248
Query: 1232 EGMMGLFSFLSENGKGCSATISSEQFVVESISNKRQ--ITSLKVQLQTKRWYHICVTHNT 1289
+ L+ F + G G SA +V SI +K + +K + ++WY + + H
Sbjct: 249 KDKPYLYCFRTSKGLGYSAHFVGGCLIVTSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIY 308
Query: 1290 QRALSGGNTIKVYIDGELVASDRFR-YPKVGEMLTRCTIGASAPITTVDVIGFNKISGGF 1348
R + ++ Y++GEL + + + +C +G+S T D N++
Sbjct: 309 NRW--KNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSE---TADA---NRV---- 356
Query: 1349 SAPFCGQLGPLYLFDDAMSAEQAMGVFSLGPDY--MYSFLPSEVGYVPENISTDSIINDK 1406
FCGQ+ +YLF +A++A Q ++ LG Y + F ++ E+ ++
Sbjct: 357 ---FCGQMTAVYLFSEALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEH---HKLLLYD 410
Query: 1407 DGLAFKMVFGYNAQASSGRALFDISP-----VLEYSPDPILYDATIMSGTLLCYRHLVQD 1461
L+ + F YN +A+ + + SP + +SP A ++ H +Q
Sbjct: 411 GKLSSAIAFTYNPRATDAQLCLESSPKDNPSIFVHSP-----HALMLQDVKAVLTHSIQS 465
Query: 1462 SVQCVGGIGVFFPLLTQLDQPVCTASDVMGNTSDQKYVEGYPIDSHVAVEVIDLLTAVLD 1521
++ +GG+ V FPL QLD ++Y+ ID + ++ + +L
Sbjct: 466 AMHSIGGVQVLFPLFAQLDY--------------RQYLSD-EIDLTICSTLLAFIMELLK 510
Query: 1522 GNLANQQYMRNMSGMSILGFLLQSVSPQHLTVDVVAALERLVTTXXXXXXXXXXXXXXXE 1581
++A Q+ M G ++G+ L+ S H++ A LE + +
Sbjct: 511 NSIAMQEQMLACKGFLVIGYSLEKSSKSHVS---RAVLELCLAFSKYLSNLQNGMPLLKQ 567
Query: 1582 ALVKLYFNPHIWIFTPLIVHRELYVSLINYFKKDGSL---LRSVCGLPRVLDMLRQFYWD 1638
+ NP IWI TP V LY L F ++ +R V + ++ L+ +YW
Sbjct: 568 LCDHVLLNPAIWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWA 627
Query: 1639 KPKRKALGTKPLLHPVTKAVIGERPNRSEISELRQLV------LILAEGGLREKASLVDI 1692
+ G P K + G RPN+ E+ LR + L++ + G++E ++
Sbjct: 628 VNPQDRSGITP------KGLDGPRPNQKEMLSLRAFLLMFIKQLVMKDSGVKED----EL 677
Query: 1693 KALVAFLEASEDDICVKDVLFMVLSLLTQKSFVASFIEHVNSLGGITILLNLIRRPQEDI 1752
+A++ +L +D + DVL ++++L+++ S I + G+ ++ L+ E I
Sbjct: 678 QAILNYLLTMHEDDNLMDVLQLLVALMSEHP--NSMIPAFDQRNGLRVIYKLLASKSEGI 735
Query: 1753 RLLAFRLIGVLIVAMFEKKGAGSSFLGTSKATAEFQRVEKIKVNH-VFSVMIESVT--TF 1809
R+ A + +G + + K+ A ++ + H +FS++ E + T
Sbjct: 736 RVQALKAMGYFLKHLAPKRKA------------------EVMLGHGLFSLLAERLMLQTN 777
Query: 1810 PFTDAVRATLFDILLGEAGPKQLPQEGSINEQANPVAAKSLSRAKLTTQISNFFRVPEKP 1869
T LF+IL+ + G + V K + +I N
Sbjct: 778 LITMTTYNVLFEILIEQIGTQ--------------VIHKQHPDPDSSVKIQN-------- 815
Query: 1870 GERVGAFVLPQVLRILFRVLANS----EDSMLRLEILKDTLGLLEANPLNSEALTLEPAW 1925
PQ+L+++ +L NS E +R L D + L + N +L W
Sbjct: 816 ---------PQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVW 866
Query: 1926 QGW 1928
Q W
Sbjct: 867 QEW 869
Query: CNT0033387
Subject: sp|Q6ZQA0|NBEL2_MOUSE Neurobeachin-like protein 2 OS=Mus musculusanchor protein OS=Mus musculus GN=Lrba PE=1 SV=1
Score = 494 bits (1272), Expect = e-139, Method: Compositional matrix adjust.
Identities = 289/779 (37%), Positives = 439/779 (56%), Gaps = 52/779 (6%)
Query: 2641 EVDRGNA-MERLDPMQGGLVKGIKRHSRWDLSQVKAVHSTRYLLQYSALEXXXXXXXXXX 2699
EVD + +++DP +G+ H +W ++++++ S RYLLQ +ALE
Sbjct: 2100 EVDEEDPNFKKIDPKILAYTEGL--HGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVM 2157
Query: 2700 XXXXXXQRLAKDIGVMI-VDLHNGRGSGKSTRGKEHIIDYIDRRKACELAEDARKQWRRR 2758
+ K + + V + G ++ R I R+ + A + ++W+ R
Sbjct: 2158 FNFPDPATVKKVVNYLPRVGVGTSFGLPQTRR-----ISLATPRQLFK-ASNMTQRWQHR 2211
Query: 2759 EMSNFDYLVTLNTLAGRSYNDMTQYPVFPWILSDYTSEKLDLSDHASFRDLSKPVGALNQ 2818
E+SNF+YL+ LNT+AGRSYND+ QYPVFPW++++Y SE+LDL+ ++FRDLSKP+GALN
Sbjct: 2212 EISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPSNFRDLSKPIGALNP 2271
Query: 2819 KRFELFEERFQNFTDPDIPSFYYGSHYSSMGIVLFYLLRLEPFTLLHRQLQGGKLDHADR 2878
KR F ERF+++ D +P F+YG+HYS+ VL +LLR+EPFT LQGGK DHADR
Sbjct: 2272 KRAAFFAERFESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADR 2331
Query: 2879 LFHSVESAFQNCLTNSGDVKELVPEFFYLPEFLVNSNGYYLGVKQDGEALGDIVLPPWAK 2938
F SV A++N ++ D+KEL+PEF+YLPE VN N Y LGV DG + D+ LPPWAK
Sbjct: 2332 TFSSVSRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAK 2391
Query: 2939 RSPELFIQLNREALESEYVSDHIHEWIDLMFGYKQRGRPAVEAANVFYHLTYEGAVDLDA 2998
S E F+++NR ALESE+VS +H+WIDL+FGYKQ+G AV A NVFY+LTYEGAV+L++
Sbjct: 2392 TSEE-FVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNS 2450
Query: 2999 MEDCTERTAIEDQIAGFGQTPIQLFKKKHPRRGPAQPIARPLYYAPASITMTSTIPAPSP 3058
+ D R A+E QI FGQTP QL + HP RG A + ++ A + + PS
Sbjct: 2451 ITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQASPLMFTDQAQQDVIMVLKFPSN 2510
Query: 3059 SPGQKVTKVVFVGLIDGLVVTINKSLSVVVRTWIT-PALQNFTFSSSQDSYFGISQEV-- 3115
SP V GL V+T+ + V W PA Q + QD + + E+
Sbjct: 2511 SPVTHVAANTQPGLAMPAVITVTANRLFAVNKWHNLPAHQG----AVQDQPYQLPVEIDP 2566
Query: 3116 -------VLSRKIYGPIVDDVSLSSCCFGTLLVRSSSFLLTCGHWDNSFKVISLDGGDLV 3168
R++ + + + S CF ++ + ++L CG WD SF+V S D G L+
Sbjct: 2567 LIACGTGTHRRQVTDLLDQSIQVHSQCF--VITSDNRYILVCGFWDKSFRVYSTDTGKLI 2624
Query: 3169 QSNSQHKDVVTSLSVA---VDGSV-VVTGSRDTTVMVWDIEHTTVSTRRLGSIKDTLTEK 3224
Q H DVVT L+ + + G+ +++GSRD T+++W + K +
Sbjct: 2625 QVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLW-----------YWNGKSSGIGD 2673
Query: 3225 HRKSDTVVISDKPRHVLCGHDDAITSVAVRVELDIVVSGSKDSTCIFHTLRTGRYVRSIR 3284
+ +T PR +L GHD IT AV EL +V+SGS++ C+ H++ G +R++
Sbjct: 2674 NPGGETAT----PRAILTGHDYEITCAAVCAELGLVLSGSQEGPCLIHSM-NGDLLRTLE 2728
Query: 3285 HPNRCPVTNL-KVSQHG-LVVVYSHGDLSLHVCSINGKWLASVDVKGRLNCMDISHCGHF 3342
P C L + S+ G V+ Y +G S+NGK A+V+ + + +S G +
Sbjct: 2729 GPENCLKPKLIQASREGHCVIFYENG--CFCTFSVNGKLQATVETDDHIRAIQLSRDGQY 2786
Query: 3343 LVCGGDQGQVLVFKLQTLEVVRRYEGAGVAVTSLTVT-PEDCFLVGTHDGALVVFSLEF 3400
L+ GGD G V+V ++ L+ + Y G + ++ ++ + C + G G++V+F +F
Sbjct: 2787 LLTGGDNGVVIVRQVSDLKQLFAYPGCDAGIRAMALSFDQRCIISGMASGSIVLFYNDF 2845
Score = 197 bits (500), Expect = 1e-48, Method: Compositional matrix adjust.
Identities = 195/901 (21%), Positives = 379/901 (42%), Gaps = 131/901 (14%)
Query: 1054 VDGSFD-PSNMLIQNEDVVLLYFSILQRCNEQDRVNGLDTFQLLLEESTANRAACVRAGL 1112
V G FD N +IQ + ++ +L++C+ + F +L++S N C GL
Sbjct: 74 VGGQFDLEMNFIIQEGESIMCMVELLEKCDVTCQAEVWSMFTAILKKSIRNLQVCTEVGL 133
Query: 1113 LSLLLEWFAKETDVALIVKFGRLMQMIGGHSISGKDMRSIFALLRSSKDGLRPRHGTLLL 1172
+ +L K D + ++ ++ ++++ ++++ F+ L+ K G P H LL
Sbjct: 134 VEKVLGKIEK-VDSMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDK-GQWPPHAGKLL 191
Query: 1173 QIFQGMLKEQGPAVFFDLSGRDSGIVVTSPL-RWPSNRGFSFCAWARVESFPAGSSPKAP 1231
+ + M ++ GP FF+ G+ + + P+ RWP GF+F W R++ ++
Sbjct: 192 SVLKHMPQKYGPDAFFNFPGKSAAAIALPPIARWPYQNGFTFHTWLRMDPV---NNINVD 248
Query: 1232 EGMMGLFSFLSENGKGCSATISSEQFVVESISNKRQ--ITSLKVQLQTKRWYHICVTHNT 1289
+ L+ F + G G SA ++ SI +K + +K + ++WY + + H
Sbjct: 249 KDKPYLYCFRTSKGLGYSAHFVGGCLIITSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIY 308
Query: 1290 QRALSGGNTIKVYIDGELVASDRFR-YPKVGEMLTRCTIGASAPITTVDVIGFNKISGGF 1348
R + ++ Y++GEL + + + +C +G+S T D N++
Sbjct: 309 NRW--KNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSE---TADA---NRV---- 356
Query: 1349 SAPFCGQLGPLYLFDDAMSAEQAMGVFSLGPDY--MYSFLPSEVGYVPENISTDSIINDK 1406
FCGQ+ +YLF DA++A Q ++ LG Y + F ++ E+ ++
Sbjct: 357 ---FCGQMTAVYLFSDALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEH---HKLLLYD 410
Query: 1407 DGLAFKMVFGYNAQASSGRALFDISP-----VLEYSPDPILYDATIMSGTLLCYRHLVQD 1461
L+ + F YN +A+ + + SP + +SP A ++ H +Q
Sbjct: 411 GKLSSAIAFMYNPRATDAQLCLESSPKDNPSIFVHSP-----HALMLQDVKAVLTHSIQS 465
Query: 1462 SVQCVGGIGVFFPLLTQLDQPVCTASDVMGNTSDQKYVEGYPIDSHVAVEVIDLLTAVLD 1521
++ +GG+ V FPL QLD ++Y+ +D + ++ + +L
Sbjct: 466 AMHSIGGVQVLFPLFAQLDY--------------KQYLSD-EVDLTICTTLLAFIMELLK 510
Query: 1522 GNLANQQYMRNMSGMSILGFLLQSVSPQHLTVDVVAALERLVTTXXXXXXXXXXXXXXXE 1581
++A Q+ M G ++G+ L+ S H++ A LE + +
Sbjct: 511 NSIAMQEQMLACKGFLVIGYSLEKSSKSHVS---RAVLELCLAFSKYLSNLQNGMPLLKQ 567
Query: 1582 ALVKLYFNPHIWIFTPLIVHRELYVSLINYFKKDGSL---LRSVCGLPRVLDMLRQFYWD 1638
+ NP +WI TP V LY L F ++ +R V + ++ L+ +YW
Sbjct: 568 LCDHILLNPAVWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWA 627
Query: 1639 KPKRKALGTKPLLHPVTKAVIGERPNRSEISELRQLV------LILAEGGLREKASLVDI 1692
+ G P K + G RPN+ EI LR + L++ + G++E ++
Sbjct: 628 VNPQDRSGITP------KGLDGPRPNQKEILSLRAFLLMFIKQLVMKDSGVKED----EL 677
Query: 1693 KALVAFLEASEDDICVKDVLFMVLSLLTQKSFVASFIEHVNSLGGITILLNLIRRPQEDI 1752
+A++ +L +D + DVL ++++L+ + S I + G+ ++ L+ E I
Sbjct: 678 QAILNYLLTMHEDDNLMDVLQLLVALMAEHP--NSMIPAFDQRNGLRVIYKLLASKSEGI 735
Query: 1753 RLLAFRLIGVLIVAMFEKKGAGSSFLGTSKATAEFQRVEKIKVNH-VFSVMIESVTTFPF 1811
R+ A + +G + + K+ A ++ + H +FS++ E +
Sbjct: 736 RVQALKALGYFLKHLAPKRKA------------------EVMLGHGLFSLLAERLML--Q 775
Query: 1812 TDAVRATLFDILLGEAGPKQLPQEGSINEQANPVAAKSLSRAKLTTQISNFFRVPEKPGE 1871
T+ + T++++L E I + V K T +I N
Sbjct: 776 TNLITMTMYNVLF----------EILIEQICTQVIHKQHPDPDSTVKIQN---------- 815
Query: 1872 RVGAFVLPQVLRILFRVLANS----EDSMLRLEILKDTLGLLEANPLNSEALTLEPAWQG 1927
PQ+L+++ +L NS E +R L D + L + N +L WQ
Sbjct: 816 -------PQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQE 868
Query: 1928 W 1928
W
Sbjct: 869 W 869
Query: CNT0033387
Subject: sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiensGN=Nbeal2 PE=2 SV=2
Score = 476 bits (1226), Expect = e-133, Method: Compositional matrix adjust.
Identities = 288/703 (40%), Positives = 398/703 (56%), Gaps = 83/703 (11%)
Query: 2738 YIDRRKACEL--AEDARKQWRRREMSNFDYLVTLNTLAGRSYNDMTQYPVFPWILSDYTS 2795
Y+ R E+ A ++W +RE+SNF+YL+ LNT+AGR+YND++QYPVFPW+L DY S
Sbjct: 2037 YLSSRSPLEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVS 2096
Query: 2796 EKLDLSDHASFRDLSKPVGALNQKRFELFEERFQNFTDP--DIPSFYYGSHYSSMGIVLF 2853
LDLS+ A FRDLSKP+G +N K +L E++++F DP I F+YG+HYS+ V+
Sbjct: 2097 PVLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMH 2156
Query: 2854 YLLRLEPFTLLHRQLQGGKLDHADRLFHSVESAFQNCLTNSGDVKELVPEFFYLPEFLVN 2913
YL+R+EPFT LH QLQ G+ D +DR FHSV +A+Q L + DVKEL+PEFFY P+FL N
Sbjct: 2157 YLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLEN 2216
Query: 2914 SNGYYLGVKQ-DGEALGDIVLPPWAKRSPELFIQLNREALESEYVSDHIHEWIDLMFGYK 2972
NG+ LG Q E +GD+VLPPWA SPE FIQ +R+ALESEYVS H+HEWIDL+FGYK
Sbjct: 2217 QNGFDLGCLQLTNEKVGDVVLPPWAG-SPEDFIQKHRQALESEYVSTHLHEWIDLIFGYK 2275
Query: 2973 QRGRPAVEAANVFYHLTYEGAVDLDAMEDCTERTAIEDQIAGFGQTPIQLFKKKHPRRGP 3032
QRG A EA NVFY+ TYEGAVDLD + D ER A+E I+ FGQTP QL K+ HP R
Sbjct: 2276 QRGPAAEEALNVFYYCTYEGAVDLDHVADERERKALEGIISNFGQTPCQLLKEPHPPRLS 2335
Query: 3033 AQPIARPLYYAPASITMTSTIPAPSPSPGQKVT--KVVF-------VGLIDGLV------ 3077
A+ A L + + SPS Q + K F V L+ LV
Sbjct: 2336 AEEAANRL----------ARLDTNSPSIFQNLNQLKAFFAEVVSEAVPLVLALVPHRQSH 2385
Query: 3078 -----------VTINKSLSVVVRTWITPALQNFT--FSSSQDSYFGISQEVVLSRKIYGP 3124
VT++ S + TW+ P +N F+ S+D G + + + + GP
Sbjct: 2386 SFITQSSSDMLVTVSASGLLGTHTWL-PYDRNINNYFTFSKDPTMGSPK---VQKLLSGP 2441
Query: 3125 IVDDVSLSSCCFGTLLVRSSSFLLTCGHWDNSFKVISLDGGDLVQSNSQHKDVVTSLSVA 3184
V D +S+ + L + GHWD S +V SL G L+ S+H D+VT L++
Sbjct: 2442 WVSDSGVSAQALA--VAPDGKLLFSGGHWDGSLRVTSLPRGRLLNQLSRHLDIVTCLALD 2499
Query: 3185 VDGSVVVTGSRDTTVMVWDIEHTTVSTRRLGSIKDTLTEKHRKSDTVVISDKPRHVLCGH 3244
G +++GSRDTT MVW + + + ++ KP VL GH
Sbjct: 2500 TCGIYLISGSRDTTCMVWRL-------------------LQQSGLSAGLAPKPVQVLYGH 2540
Query: 3245 DDAITSVAVRVELDIVVSGSKDSTCIFHTLRTGRYVRSIRHPNRC---PVTNLKVSQHGL 3301
A++ VA+ ELD+ VSGS+D T I HT+R G++V ++R P P+++L + G
Sbjct: 2541 VAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPPGATLPGPISHLALGAEGQ 2600
Query: 3302 VVVYSHG--------DLSLHVCSINGKWLASVDVKGRLNCMDISHCGHFLVCGGDQGQVL 3353
+VV S SLH+ S+NG+ ASV + + + ++ F++ G Q +
Sbjct: 2601 IVVQSSACERPGAQVTYSLHLYSVNGRLRASVTLTEQPTALTVAE--DFVLLGTAQCSLH 2658
Query: 3354 VFKLQTLEVVRRYEGAGVAVTSLTVTPEDC-FLVGTHDGALVV 3395
+ L L V V S++VT E LVG DG L+V
Sbjct: 2659 ILHLNKLRPAVPPLPMKVPVHSVSVTKERSHVLVGLEDGKLIV 2701
Score = 135 bits (340), Expect = 6e-30, Method: Compositional matrix adjust.
Identities = 204/918 (22%), Positives = 352/918 (38%), Gaps = 183/918 (19%)
Query: 968 QALFRDGECFVHIVTLLNEER-------PAEVGSQLS---------------------LD 999
QA F CF H++ L+ + P E S L+ +
Sbjct: 323 QATFLSNNCFEHLIRLIQNSKLYLQARAPPEGDSDLATWLLTEPDVQKVLDQDTDAIAVH 382
Query: 1000 VLFTLTRLLQGNEASKASFRSIVGAGYKTLEFVLIELHNGKPSREXXXXXXXXXVDG--S 1057
V+ LT ++ G+ ++K F+ +G Y+ L+ VL +G P+ V+G S
Sbjct: 383 VVRVLTCIMSGSPSAKEVFKERIG--YQHLQEVLQS--HGPPTHRLLQELLNMAVEGDHS 438
Query: 1058 FDPSNMLIQNEDVVLLYFSILQRCNEQD-RVNGLDTFQLLLEESTANRAACVRAGLLSLL 1116
P I+NE VL+ L + R+ L + A+R CV+AGL+ L
Sbjct: 439 MHPPPP-IRNEQPVLVLMQWLPALPTAELRLFLAQRLWWLCDSCPASRTTCVQAGLVGYL 497
Query: 1117 LEWFAKETDVALIVKFGRLMQMIGGHSISGKDMRSIFALL--------RSSKDGLRPRHG 1168
LE T + + L + +S + + L S + + RH
Sbjct: 498 LETLNTGTALGARCQEQLLALLQALGRVSLRPLELRRLLRPPPGLDSESSGNESQKARHA 557
Query: 1169 TLLLQIFQGMLKEQGPAV---FFDLSGRDSGIVVTSPLRWPSNRGFSFCAWARVESFPA- 1224
+++ GM + +GPA +FDL+ +GI+V RWP GF+F AW ++S A
Sbjct: 558 GAVIRALSGMARHRGPARALRYFDLTPSMAGIMVPPVQRWP-GAGFTFHAWLCLQSSEAV 616
Query: 1225 -GSSPKAPEGMMGLFSFLSENGKGCSATISSEQFVVESISNKRQITSL---KVQLQTKRW 1280
S+P P L+SF + +G G A ++ +V ++ +++ ++ +V W
Sbjct: 617 PTSAPSRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYVTVNLPEVSFADSAW 676
Query: 1281 YHICVTHNTQRALSGGNTIKVYIDGELVASDRFRYPKVGEMLTRCTIGASA--------- 1331
+ + + H R N + V+ DG LV + FR+P + E + C IG++
Sbjct: 677 HCVAIVHVPGRRPFSQNLVNVFKDGHLVKTVPFRFPSLSEPFSSCCIGSAGHRTTTTTTG 736
Query: 1332 -PITTVD----------------------------------------VIGFNKISGGFSA 1350
P ++V + G G
Sbjct: 737 LPASSVSTALAHTHPSLTRSQSVPASTGLGWGPGLGTPLQEGSVSSTLAGTQDTRWGSPT 796
Query: 1351 PFCGQLGPLYLFDDAMSAEQAMGVFSLGPDYMYSFLPSEVGYVPENISTDSIINDKDGLA 1410
G+LG + +F +A+ + SLGP+ F P +
Sbjct: 797 SLEGELGAVAIFHEALQPSALRVLCSLGPNEPAPFKPE---------------GELHEFG 841
Query: 1411 FKMVFGYNAQASSGRALFDISPVLEYSPDPILYDATIMSGTLLCYR---HLVQDSVQCVG 1467
K++ Y+ QA D+SP + G L +R V+D V CVG
Sbjct: 842 TKLLLHYSPQACKNNICLDLSP------------GHGLDGRLTGHRVETWDVKDVVNCVG 889
Query: 1468 GIGVFFPLLTQLD-QP------VCTASDVMG-NTSDQKYVEG--YPI--------DSHVA 1509
G+GV PLL ++ QP C D++G + + +G P+ + +
Sbjct: 890 GMGVLLPLLERVAVQPQEAEAGPCETHDLVGPELTSGRNTQGLLLPLGKSSEDRMERNAV 949
Query: 1510 VEVIDLLTAVLDGNLANQQYMRNMSGMSILGFLLQSVSPQHLTVDVVAALERLVTTXXXX 1569
+ +L L + NQ+ + G +I+G LL+ V + ++V+ + + L+
Sbjct: 950 AAFLLMLRNFLQNHTVNQESLVQCQGPAIIGALLRKVPSSAMDMNVLMSAQLLM----EQ 1005
Query: 1570 XXXXXXXXXXXEALVKLYFNPHIWIFTPLIV---HRELYVSLINYFKKDGSLLRSVCGLP 1626
L FN H+W + V H + S++ ++ LR G+
Sbjct: 1006 AAADGGGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSMVREHRQK---LRKKYGVQ 1062
Query: 1627 RVLDMLRQFYWDKPKRKALGTKPLLHPVTKAVIGERP-NRSEISELRQLVLILAEGGLRE 1685
+LD LR Y P+R ERP ++ ++ +L L L
Sbjct: 1063 FLLDALRTHY--SPQR------------------ERPLAADDLRTVQTSLLGLVREFLVR 1102
Query: 1686 KASLVDIKALVAFLEASEDDICVKDVLFMVLSLLTQKSFVASFIEHVNSLGGITILLNLI 1745
S+ D++ ++ FL A+ DD V L ++L+LL + LG + +LL L+
Sbjct: 1103 NFSVEDMQVVLNFLAATGDDGQVVGTLELLLTLLQGSPVQDPLAAFLLELGNLEVLLALL 1162
Query: 1746 RRPQEDIRLLAFRLIGVL 1763
RP+ LL R+ +L
Sbjct: 1163 VRPK-STPLLTDRVCKIL 1179