Query: CNT0033555
Subject: sp|P29375|KDM5A_HUMAN Lysine-specific demethylase 5A OS=Homo sapiensOS=Arabidopsis thaliana GN=MBD9 PE=2 SV=1
Score = 307 bits (786), Expect = 3e-82, Method: Compositional matrix adjust.
Identities = 225/694 (32%), Positives = 349/694 (50%), Gaps = 127/694 (18%)
Query: 1406 GKESNLHALEEEQSGTKNAVEVFKGTVSKGI-AFLAEAHIPLLKFLVSDLKFRISRGL-- 1462
K ++ L+E+++G + ++ + + A L AHI LL+ L+ +L+ +++ +
Sbjct: 846 AKNTSASELKEKKAGDSSDFKISDSSRGSCVGALLTRAHISLLQVLICELQSKVAAFVDP 905
Query: 1463 NEDEVEEPKKRGRKRICDVGPLPPEFGD--DLPMNAVTWPEVAHRYLVAILDVKKHGDIT 1520
N D E +RGRK+ D L + LP+N TWPE+A RY++++L + + +
Sbjct: 906 NFDSGESRSRRGRKK--DDSTLSAKRNKLHMLPVNEFTWPELARRYILSLLSMDGNLESA 963
Query: 1521 ELAPDERKKLMRYFXXXXXXXXXXXXXXXXXXSDAQNLTNAVFVLDTQHYSWKVLAEAEK 1580
E+A E K+ R D L ++ + +LAEA K
Sbjct: 964 EIAARESGKVFRCL-----------------QGDGGLLCGSLTGVAGMEADSMLLAEAIK 1006
Query: 1581 ELTVRMPKTVEKDIVIFVPQEWD-VALTPINPAPKKAKNRKTGDLDPLPKWVEALEPVRK 1639
+++ + T E D++ + D + T N +GD +P+W + LEPV+K
Sbjct: 1007 KISGSL--TSENDVLSVEDDDSDGLDATETNTC--------SGD---IPEWAQVLEPVKK 1053
Query: 1640 MPTNLGTKLKLQVQEALDYDPPDWAKGTLEWSLSKGTFKSNAAGTTKRAVLEVLAQYHGE 1699
+PTN+GT+++ V EAL+ +PP+WAK LE S+SK +K NA+G TK+AVL +LA G
Sbjct: 1054 LPTNVGTRIRKCVYEALERNPPEWAKKILEHSISKEIYKGNASGPTKKAVLSLLADIRGG 1113
Query: 1700 ELKAINAPRIRKVKAAPSAEHLMQRCRIVLREVAKADSKQVFGNLMGGASAVKSSKD--- 1756
+L + +K ++ +M++CR VLR VA AD +V L+G S D
Sbjct: 1114 DLVQRSIKGTKKRTYISVSDVIMKKCRAVLRGVAAADEDKVLCTLLGRKLLNSSDNDDDG 1173
Query: 1757 -VGT---LARPLDFRTIDARLAAGAYGGSTDAFAADMRQIWKNVESVHKSGSAILELANT 1812
+G+ ++RPLDFRTID RLAAGAY GST+AF D+ ++W ++ ++ ++L T
Sbjct: 1174 LLGSPAMVSRPLDFRTIDLRLAAGAYDGSTEAFLEDVLELWSSIRVMYADQPDCVDLVAT 1233
Query: 1813 LSQLFEKLYLKQVVSLIKGMPDTK-------DDKEKVSDVDTKVDGSVRSNSKAGTKGSG 1865
LS+ F+ LY +VV L++ + D + + K+++ D+ V
Sbjct: 1234 LSEKFKSLYEAEVVPLVQKLKDYRKLECLSAEMKKEIKDIVVSV---------------- 1277
Query: 1866 NAADDKLGKAPWEDDTTCRVCGVDEDYDSILLCDGCDAEYHIYCLVPPLEKVPKGNWFCP 1925
+KL KAPW D+ C+VCGVD+D DS+LLCD CDAEYH YCL PPL ++P GNW+CP
Sbjct: 1278 ----NKLPKAPW-DEGVCKVCGVDKDDDSVLLCDTCDAEYHTYCLNPPLIRIPDGNWYCP 1332
Query: 1926 SCVAVEEGYPEAPSLGEAELREMQEEKERPVAGSILKLEYEDEKVPSIVLEKKPEAEKIG 1985
SCV + R QE E S L ++ + K
Sbjct: 1333 SCVIAK--------------RMAQEALE------------------SYKLVRRRKGRKYQ 1360
Query: 1986 RELRSGIVAGLAVEDEALCEEPDAHFPAVEISVEALLKKLEEKDYWQLSLPDKLFVLKFL 2045
EL + E AH V +EEKDYW+ S +++ +LK L
Sbjct: 1361 GELTRASM------------ELTAHLADV----------MEEKDYWEFSAEERILLLKLL 1398
Query: 2046 CDEALKTPQARAHLEKSVEVTLELQQQLRDLVAE 2079
CDE L + HLE+ E +E+QQ+LR L +E
Sbjct: 1399 CDELLSSSLVHQHLEQCAEAIIEMQQKLRSLSSE 1432
Score = 80.1 bits (196), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 86/314 (27%), Positives = 128/314 (40%), Gaps = 66/314 (21%)
Query: 2363 DAQATASKILE----DKDARTKALQTARELDMKITKLGSKLFNLTLRREHIGTDHLGREY 2418
DA + AS+ L+ D A + +Q L I + S+L ++RR+ +GTD GR Y
Sbjct: 1585 DASSQASQELQACQQDLSATSNEIQN---LQQSIRSIESQLLKQSIRRDFLGTDASGRLY 1641
Query: 2419 WALTGIDGRPCLVVADTSAPQERAGQGTNSGSCSQTVEFQGIEDRTTSPIVPSVSKGSSE 2478
W D P ++V S S + V+ I + SP + +V G
Sbjct: 1642 WGCCFPDENPRILV-------------DGSISLQKPVQADLIGSKVPSPFLHTVDHGR-- 1686
Query: 2479 DKEKDVLNLKTMQERTKWVHYKGDKALDELVKWLSPRDQHERVLRISIYHWRRSLYPRHL 2538
L L + W +Y+ + + ELV+WL D ER LR SI W+R Y
Sbjct: 1687 ------LRL------SPWTYYETETEISELVQWLHDDDLKERDLRESILWWKRLRYGD-- 1732
Query: 2539 LYMPDMKTAVTTTEPSKVVDESRAIKETPFSEMEEISHIRSFPAVNARKLLLKRHTALNT 2598
+ K A + P ++ ME+ R P + LK+
Sbjct: 1733 -VQKEKKQAQNLSAPVFAT----GLETKAAMSMEK----RYGPCIKLEMETLKKR----- 1778
Query: 2599 SSRSDLVHQKESHDSKEILDKKSSVLRRCECLELLWDSRYHCLSCHETYESSAEFQTHS- 2657
+ V ++E L RCECLE + S HCL CH+T+ S EF+ H+
Sbjct: 1779 -GKKTKVAEREK-------------LCRCECLESILPSMIHCLICHKTFASDDEFEDHTE 1824
Query: 2658 NDCPPGSKPSTENG 2671
+ C P S +TE G
Sbjct: 1825 SKCIPYSL-ATEEG 1837
Score = 70.9 bits (172), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 61/214 (28%), Positives = 86/214 (40%), Gaps = 57/214 (26%)
Query: 582 LNQLRTFITALKGNLAEDWRVILRKRPTGAQE-KFYLSPAKRKYRSRQDVARFLGL---- 636
L LR FI+ G L + WRV R+ G Q Y +P + + S Q+VA +LGL
Sbjct: 254 LQNLRHFISERHGVLEDGWRVEFRQPLNGYQLCAVYCAPNGKTFSSIQEVACYLGLAING 313
Query: 637 -------------------VDDPKCQRTK-------PCNLGTSLDK-----PLDKNNSHP 665
+ PK ++T P G+S+ P + P
Sbjct: 314 NYSCMDAEIRNENSLLQERLHTPKRRKTSRWPNNGFPEQKGSSVSAQLRRFPFNGQTMSP 373
Query: 666 PASQAN--------------------AVTNLPMFCGDVMIEKLGVIDSRPTYSDEHHIWP 705
A ++ A PM D + LG ID R +Y + + I+P
Sbjct: 374 FAVKSGTHFQAGGSLSSGNNGCGCEEAKNGCPMQFEDFFVLSLGRIDIRQSYHNVNVIYP 433
Query: 706 VGFRSSWHDPETRSYCISEVEDGGELGPIFRVTR 739
+G++S WHD T S EV DG GPIF+VTR
Sbjct: 434 IGYKSCWHDKITGSLFTCEVSDGNS-GPIFKVTR 466
Score = 58.9 bits (141), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 34/93 (36%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 192 EAVDAVMEIHGVRKQVTGHAVSFPGVAGPESGRLCHCCSRPESSKSTIFCDKCERGFHVD 251
E V+ V IH G P P+ C C RPES + + CD CERGFH+
Sbjct: 55 EPVEVVRSIHDNPDPAPGAPAEVPE---PDRDASCGACGRPESIELVVVCDACERGFHMS 111
Query: 252 CVKHWPKPAQELDVWHCGPC--GLQPGHYWPLG 282
CV + A D W C C G + WPLG
Sbjct: 112 CVNDGVEAAPSAD-WMCSDCRTGGERSKLWPLG 143
Query: CNT0033555
Subject: sp|Q9P1Y6|PHRF1_HUMAN PHD and RING finger domain-containing protein 1GN=KDM5A PE=1 SV=3
Score = 80.9 bits (198), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 44/125 (35%), Positives = 60/125 (48%), Gaps = 12/125 (9%)
Query: 1824 QVVSLIKGMPDTKDDKEKVSDVDTKVDG-SVRSNSKAGTKGSGNAADDKLGKAPWEDDTT 1882
+VV L G D +D+ + V + D +++ + GT + D
Sbjct: 247 KVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVN-----------FVDLYV 295
Query: 1883 CRVCGVDEDYDSILLCDGCDAEYHIYCLVPPLEKVPKGNWFCPSCVAVEEGYPEAPSLGE 1942
C CG + D +LLCDGCD YH +CL+PPL VPKG+W CP CVA E P E
Sbjct: 296 CMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFE 355
Query: 1943 AELRE 1947
+RE
Sbjct: 356 QAVRE 360
Query: CNT0033555
Subject: sp|Q80Y84|KDM5B_MOUSE Lysine-specific demethylase 5B OS=Mus musculusOS=Homo sapiens GN=PHRF1 PE=1 SV=3
Score = 80.9 bits (198), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 31/52 (59%), Positives = 36/52 (69%)
Query: 1878 EDDTTCRVCGVDEDYDSILLCDGCDAEYHIYCLVPPLEKVPKGNWFCPSCVA 1929
ED T C VCG + D +LLCDGCDA YH+ CL PPL++VP WFCP C A
Sbjct: 181 EDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAA 232
Query: CNT0033555
Subject: sp|Q9UGL1|KDM5B_HUMAN Lysine-specific demethylase 5B OS=Homo sapiensGN=Kdm5b PE=1 SV=1
Score = 80.9 bits (198), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 44/114 (38%), Positives = 57/114 (50%), Gaps = 19/114 (16%)
Query: 1823 KQVVSLIKGMPDTKDDKEKVSDVDTKVDGSVRSNSKAGTKGSGNAADDKLGKAPWEDDTT 1882
K++ S IK P K D E S+ + K+ K + A D +
Sbjct: 271 KEMKSTIKQEPTEKKDCELESE---------KEKPKSRAKKTATAVDLYV---------- 311
Query: 1883 CRVCGVDEDYDSILLCDGCDAEYHIYCLVPPLEKVPKGNWFCPSCVAVEEGYPE 1936
C +CG D D +LLCDGCD YH +CLVPPL VPKG+W CP C+A E P+
Sbjct: 312 CLLCGSGNDEDRLLLCDGCDDSYHTFCLVPPLHDVPKGDWRCPKCLAQECNKPQ 365
Query: CNT0033555
Subject: sp|A6H619|PHRF1_MOUSE PHD and RING finger domain-containing protein 1GN=KDM5B PE=1 SV=3
Score = 79.7 bits (195), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 31/58 (53%), Positives = 38/58 (65%)
Query: 1879 DDTTCRVCGVDEDYDSILLCDGCDAEYHIYCLVPPLEKVPKGNWFCPSCVAVEEGYPE 1936
D C +CG D D +LLCDGCD YH +CL+PPL VPKG+W CP C+A E P+
Sbjct: 308 DLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQ 365