Query: CNT0034414
Subject: sp|Q8IZQ1|WDFY3_HUMAN WD repeat and FYVE domain-containing protein 3OS=Dictyostelium discoideum GN=lvsA PE=3 SV=2
Score = 623 bits (1606), Expect = e-178, Method: Compositional matrix adjust.
Identities = 351/873 (40%), Positives = 494/873 (56%), Gaps = 111/873 (12%)
Query: 2841 PEEANYLEQEMHEDGEYLIRPHLEPGERIRFRYNCERVVGLDKRDGIFLIGEKCLYVIEN 2900
P + +YL+ M +D P L YNC V G+DK +GI + +Y+ +
Sbjct: 2795 PYDQSYLKDAMRKD------PRLNG-----IMYNCGSVDGMDKIEGILIFCPVYMYIFDG 2843
Query: 2901 YIIDENKCIKEKGEERDLSVIDRALGVRANSARVVDTHSSKQGEVVADSW-PGGRAWAYS 2959
Y DEN D+S ++ E + W P G
Sbjct: 2844 YYKDENTG--------DISEVE---------------------EKINSEWLPEGTV---- 2870
Query: 2960 GGAWGKEKVKAGQNMPHPWRMWKLESVHELLKRRYQLRPVAIELFSMDGCNDLLVFHKN- 3018
+ + + H + W E + ++LKRRY LR VA+E+FS DG N+L+V+
Sbjct: 2871 --------LPMKKKIIHYFLKWAYEDIRDVLKRRYLLRQVALEIFSTDGRNNLVVYRDEP 2922
Query: 3019 ERDEVFKNLLAMNLPRNSMLDTTISAASKQEAG-------------------EGGRLFKM 3059
RDEV+ L+ N TI ++ G R +
Sbjct: 2923 TRDEVYHTLV-----NNVSSHNTIGGDAQGITGGQTGNDDNDDHHGGGGGRGVRDRFTSI 2977
Query: 3060 MAKS-FSKRWQNGEISNFQYLMHLNTLAGRGYNDLTQYPVFPWILKDYTSEELDLSNPDT 3118
KS + +WQ G+ISNFQYLMHLNTLAGR YNDLTQYPVFPW+L DY SEELD+ +P
Sbjct: 2978 WRKSPLTLKWQQGQISNFQYLMHLNTLAGRSYNDLTQYPVFPWVLSDYESEELDIDDPKV 3037
Query: 3119 FRRLDKPMGALHPEREKEFRKRYETWEDPE-------IPRFHYGSHYSSAGSVLFYLIRL 3171
+R L KPMGAL R ++FR+R+E W+D E +P+FHYG+HYSSA VL+YLIRL
Sbjct: 3038 YRDLSKPMGALEESRAQKFRERFENWDDQEPNEHGHKVPKFHYGTHYSSAAIVLYYLIRL 3097
Query: 3172 PPFSQENKQLQGGSFDHSDRLFNSIKDTWLSASQGNTADVKELIPEFFYLPEFLENRFGF 3231
PF+Q +LQGG +D DRLF+SI + W S+SQG+T V ELIPEF+YL EFL N F
Sbjct: 3098 EPFTQHFLKLQGGRWDQPDRLFSSITEAWASSSQGSTGVVMELIPEFYYLDEFLVNNNKF 3157
Query: 3232 DFGTKQSGEKVNDVLLPPWAKGSAREFVRKHREALESQYVSENLHHWIDLIFGFKQRGKP 3291
+FGTKQ GE ++D++LPPWAKGS +EF++ HR+ALES YVSE+LH WIDLIFG++Q+GK
Sbjct: 3158 NFGTKQGGEPIDDIILPPWAKGSPQEFIKLHRKALESDYVSEHLHEWIDLIFGYRQQGKA 3217
Query: 3292 AVEALNVFYYLTYEGAVDIDRVPDPGMKAAILAQINHFGQTPKLLFTKPHSKRKWVQKQP 3351
A ++LNVFYYLTYEGAV+ID + DP KAA +AQIN+FGQTPK LF KPH KR
Sbjct: 3218 ADDSLNVFYYLTYEGAVNIDAISDPVEKAATIAQINNFGQTPKQLFDKPHPKR-----NA 3272
Query: 3352 LALALRNY-HLLAPQEMRPLSSRVSQIVIFQDKVYAAGANRILKPPSYSKYLSWGFSDRS 3410
+ L Y L ++ + V QI + D+ G N++L PP++SKY+ WG D S
Sbjct: 3273 TLMGLPFYAKALTGNFIKDIGEPVGQIRLINDRATCVGFNKVLLPPNHSKYMLWGLPDGS 3332
Query: 3411 LRIVSYDQERLLSTHENLHDDGPVLCAGFSRDGRILVTGGSDGVVSVWRQRKDGLRGQRR 3470
+R + D+ ++L H DGP+ C + DGRI V+GGSD ++ V+ +R
Sbjct: 3333 IRYNTGDKIKVLEDHH----DGPLTCLTATEDGRICVSGGSDSLICVY--------NLKR 3380
Query: 3471 LHLQKSLCAHTQSVICLAVSQPYSLIVSGSKDRTVIFWDLSSLEYVRQLPELPDPPTAIH 3530
L K L HT S+ C++ S+PYS+IVSGS DRT I WDL+ L YVR L P + I
Sbjct: 3381 FSLAKRLSGHTGSITCVSASRPYSIIVSGSDDRTCIIWDLNRLCYVRSLDAHEGPISCIG 3440
Query: 3531 ANDMTGEVVTASGTTLSVWSINGDCLAAVNTSHVAADTILSITSPHLSDWMEASWYVTGH 3590
+D TGE+V SGTT+SV+++NG+ L TS +A D I +W+ + +TGH
Sbjct: 3441 IHDTTGEIVVCSGTTISVYTVNGELLINYKTSQIANDQITCCIWSKGPEWLGENVLLTGH 3500
Query: 3591 QNGVIRLWHMEL----DNHSKLDRKASHRISDSWGLNMSKSCITGGPPEYQLVLYKVLS- 3645
++G +++W +E DN++ + ++ +++ + + + ++L S
Sbjct: 3501 RDGKVKVWGLETRLLPDNNNSNNNNNNNNNNNNNATQIPSTNNNKLKFKNVIILRATFSN 3560
Query: 3646 --WHKKPVTALSLGNDLKQLCSGDAGGHLVSWT 3676
H +T++ L ND ++ +GD G + W+
Sbjct: 3561 SQSHSTAITSIFLTNDQQKFYTGDITGRVCMWS 3593
Score = 159 bits (401), Expect = 6e-37, Method: Compositional matrix adjust.
Identities = 193/863 (22%), Positives = 350/863 (40%), Gaps = 153/863 (17%)
Query: 764 DCLLSLLKKSDGNQTVFRKANGVGYILPLVASASQRSGALRVLSCLICEDVNQAHADELK 823
D L L+ ++ N ++ R + +L + +S R +LR+L LI D + E
Sbjct: 730 DSLFILISENPDNISLIRSFSIFNILLRFLPYSSVRGKSLRILQQLIKYDP-EPTQKEFD 788
Query: 824 SLLKIAHSGIVYGQNGLPIGLDTEGKEDILWAVWRILGANFTTRVVFGDGNGFGLLLSVL 883
L+K+ S + P+ K DIL A ++ + R F + GF ++SV
Sbjct: 789 GLIKVLTS---VNKENYPM------KSDILNATRKLFNISKHARDSFREHGGFVSIISVF 839
Query: 884 EGIQSRHENSSAESVADEAAFVPNLT-------EHMEVLDALLHVVTVGAAEYPPNRNKL 936
++ E++F PN E +E+++++ T NR
Sbjct: 840 --------------ISLESSFSPNRKDSRNWDMEKLELIESICRCTTSALCGNVINRENF 885
Query: 937 HECISSQTFKRLLQTSGLLCSDFEEKVAERLFDVALERVLSPSQSALGLPILLQGDGTKS 996
+ I +TF L +G+L ++F + V + +FD+ E + + Q +
Sbjct: 886 EQQIGYKTFSSCLIMTGVLGTEFSKSVVDFIFDMVTENLNASDQIS-------------- 931
Query: 997 FRIPGAEKDFPVNPGQIAQIDVYNPGAIAVLLFFLPQFSAK-LQLRILIQVERIVSKSPW 1055
Q+ + N + V+L +P K +L+I+ ++ ++ +
Sbjct: 932 -----------------NQMIINNVESFNVILDIIPHIENKDFRLQIISRINKMAEYGRY 974
Query: 1056 NQNALTSAGCVGDLLEAVKSMMQTKPSPLLSYSLKIVEVLGSFRLSYSEMQTLGRIIWLN 1115
NQ AL+ +L S + PL L +++ +G+ LS SE++ +++
Sbjct: 975 NQEALSKLSIPDWILSRFPSNLSNANDPLQPLLLSLIQTVGANCLSGSELRQFVKLLQPE 1034
Query: 1116 RDASDGKMGQRLLLMVERMXXXXXXXXXXXXXXXXIEFRMSRIGHACIRTPLGDRAWPPT 1175
+ LL ++ M EF +S+I IR P+ +RAWPPT
Sbjct: 1035 HSP------EVLLKILSSM-------AKSPPTPPYFEFNLSKIPFGYIRVPITERAWPPT 1081
Query: 1176 AGYSFVCWARFEKL-------TQSGPNTNGAEATKESNRNRSGSLGSVLRIFTVGTAEEK 1228
GY+ + W +K + + N + +N N + + + + + + ++K
Sbjct: 1082 NGYTIMFWLYIDKFPTVNNNNNNNNSSNNSNNSNNSNNNNNNNNNNDQIDLVHIYSDDKK 1141
Query: 1229 STVCAELFLSDSGVLTL-ATSPTSYVC-FKGVRLEEGIWYHLTIVHNKPNALAGLFQSSV 1286
S++ L +G++T+ + + YV + EG WYH+ IVH + L +
Sbjct: 1142 SSLYIYL---KNGIITVNIINSSKYVIEIPSYKFVEGKWYHIGIVHAR-----RLLGGTD 1193
Query: 1287 AHLYLNGSLRHTG-KLGYSASPTEKSLQVT-IGTPPSFSEVSPLTWQLGSCYLFEEVLPA 1344
L+++G L++T K Y A T S+ + IG + W++G+ YL E+ L A
Sbjct: 1194 FKLFVDGFLKYTATKAQYPAQITSGSMLICDIGVSNQNRFPTDSIWRIGTFYLLEDSLGA 1253
Query: 1345 PAIFFMYVLGRGYRGLFQDTDLLQFIP---YEACGGGNLMVLESLDT-ELLASLRAEGVS 1400
I +Y LG Y F+ +F P YE NLM ++ LD + L L VS
Sbjct: 1254 KHINTIYFLGPNYASNFKG----RFSPYQTYEIVNSANLMAIKDLDYGDQLGPLNLAKVS 1309
Query: 1401 QSAG--------------VALSEGSGVIWDLEKLARFWAQLCGRH----LIFAYDGSNAE 1442
+ + S V+++ E +L H +F+ +
Sbjct: 1310 MQIDENKILVGLCASNKLIRTNNSSKVVYN-EIFNGIINELSQNHGVALNVFSSPNGTSP 1368
Query: 1443 NVVP--------------------AGAISIVNLVDPMSAAASVLGGLPRLARIYGDVHIC 1482
N+ G + I+N D + VL G V
Sbjct: 1369 NLTGLQNNNNNNNNSGGSNSKKDLEGRVEIINQADLTTKLRGVL---------IGSVEAF 1419
Query: 1483 TPCNIADSMRKVGGVAVVLAMIEAADTCETLHLALSVLVSMLQSNPRNARDMQACRGYHL 1542
+ADS++K+GG+ + L ++E A++ ETL +L +LV ++Q +P N +M GY L
Sbjct: 1420 RRNKVADSIKKIGGMPISLLLLEKANSEETLFDSLGLLVGLIQYHPTNTHEMSQINGYEL 1479
Query: 1543 LALFLHRR--MDCFEARDLDFLF 1563
LA L ++ + F + L+ LF
Sbjct: 1480 LAWVLKKKASLGLFNSNILELLF 1502
Score = 52.0 bits (123), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/121 (24%), Positives = 58/121 (47%)
Query: 595 QTFQDIFLKTGNXXXXXXXXXXXXXXFASHPDNYVLVQELRTMPLFLQNMGKYLLILQER 654
+ + FLK+ ++S+ N++L+Q T+ F+Q L+
Sbjct: 504 KVLERYFLKSNYEENRVKILDRILSVYSSNTVNFILLQHTSTLTKFIQEYESLSNGLKYH 563
Query: 655 LLKVLEYAVTVVNCVPEQELLSLCYLLQQPYESSLRKIVLTFFEKLLSFDRNYKKVLREV 714
++K++ + VTV+NCVP QEL + L+ + +++ L++F+ YK + RE
Sbjct: 564 VMKIVCFVVTVLNCVPFQELSTFSLLVGENPSFYTLEMINQLITTLVNFEFRYKHIFRET 623
Query: 715 G 715
G
Sbjct: 624 G 624
Query: CNT0034414
Subject: sp|Q6VNB8|WDFY3_MOUSE WD repeat and FYVE domain-containing protein 3OS=Homo sapiens GN=WDFY3 PE=1 SV=2
Score = 617 bits (1591), Expect = e-176, Method: Compositional matrix adjust.
Identities = 367/1009 (36%), Positives = 543/1009 (53%), Gaps = 108/1009 (10%)
Query: 2627 LELVREAMAAELRVLRQDKYGWILHAENGWANHLQQLVHERGIW--PIVSEVRDEEPDWQ 2684
+ +VR+ + + + ++ + + + W +L+ ERG+W PI S + W
Sbjct: 2315 IAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDK----WM 2370
Query: 2685 LCPTEGPYXXXXXXXXXXXXISVFEKSQLMVERETEALDRCTPIDVINPSDKENALHNQY 2744
L TEGP + + E+ET P D +Y
Sbjct: 2371 LEMTEGPCRMRKKMVRNDMFYNHYPYVP-ETEQETNVASEIPSKQPETPDDIPQKKPARY 2429
Query: 2745 VDIFNFDTQKRLGYSSKEFLVSLEEDISELKNEIGEEEEDVLSARVDWNEEPFPSGSESQ 2804
++ + Y SKE+ + L + + E + +A+ + P E
Sbjct: 2430 --------RRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQE------PEHGEDT 2475
Query: 2805 VPKAMSVASLKL--------AGEEVTDQTLGSSQGRGSPAEKDVPEEANYLEQEMHEDGE 2856
+ K + L G+E + L +D E + +E+E D
Sbjct: 2476 IAKVKGLVKPPLKRSRSAPDGGDEENQEQL-----------QDQIAEGSSIEEEEKTDNA 2524
Query: 2857 YLIRPHLEPGERIRFRYNCERVVGLDKRDGIFLIGEKCLYVIENYIIDENKCIKEKGEER 2916
L+R LE GE+I+ Y C RV GLD +G+ L G++ YVI+ + + + E R
Sbjct: 2525 TLLR-LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATR------EIR 2577
Query: 2917 DLSVIDRALGVRANSARVVDTHSSKQGEVVADSWPGGRAWAYSGGAWGKEKVKAGQNMPH 2976
D+ + N + ++QG +
Sbjct: 2578 DIETLP------PNMHEPIIPRGARQGP---------------------------SQLKR 2604
Query: 2977 PWRMWKLESVHELLKRRYQLRPVAIELFSMDGCNDLLVFHKNERDEVFKNLLAMNLPRNS 3036
++ E + E+ KRRY L+P+A+E+FS DG N LL F K R++V++ LA+ +P S
Sbjct: 2605 TCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAV-VP--S 2661
Query: 3037 MLDTTISAASKQ-----EAGEGGRLFKMMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYN 3091
+ D++ S + ++ E G G + KS ++RW+ GEISNFQYLMHLNTLAGR YN
Sbjct: 2662 LTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYN 2721
Query: 3092 DLTQYPVFPWILKDYTSEELDLSNPDTFRRLDKPMGALHPEREKEFRKRYETWEDP--EI 3149
DL QYPVFPWIL DY SEE+DL+NP TFR L KPMGA ER +++KRY+ WEDP E
Sbjct: 2722 DLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGET 2781
Query: 3150 PRFHYGSHYSSAGSVLFYLIRLPPFSQENKQLQGGSFDHSDRLFNSIKDTWLSASQGNTA 3209
P +HYG+HYSSA V YL+R+ PF+Q +LQGG FD +DR+F+S+++ W SAS+ N A
Sbjct: 2782 PAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMA 2841
Query: 3210 DVKELIPEFFYLPEFLENRFGFDFGTKQSGEKVNDVLLPPWAKGSAREFVRKHREALESQ 3269
DVKELIPEFFYLPEFL N FD G KQ+G K+ DV+LPPWAKG REF+R HREALE
Sbjct: 2842 DVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECD 2901
Query: 3270 YVSENLHHWIDLIFGFKQRGKPAVEALNVFYYLTYEGAVDIDRVPDPGMKAAILAQINHF 3329
YVS +LH WIDLIFG+KQ+G AVEA+NVF++L YEG VDI + DP + A + IN+F
Sbjct: 2902 YVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNF 2961
Query: 3330 GQTPKLLFTKPHSKRKW------------VQKQPLALALRNYHL--LAPQ--EMRPLSSR 3373
GQ PK LF KPH ++ V + + +HL L P ++ L
Sbjct: 2962 GQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEP 3021
Query: 3374 VSQIVIFQDKVYAAGANRILKPPSYSKYLSWGFSDRSLRIVSYDQERLLSTHENLHDDGP 3433
V QIV + A N++L PP+++K +WG++D S R+ +Y+ ++ ++ +E L + G
Sbjct: 3022 VGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQ 3081
Query: 3434 VLCAGFSRDGRILVTGGSDGVVSVWRQRKDGLRGQRRLHLQKSLCAHTQSVICLAVSQPY 3493
+LCA + ++++TGG+ VV VW + + + L+++L HT +V C S Y
Sbjct: 3082 ILCA-ICPNPKLVITGGTSTVVCVWEMGTSKEKA-KTVTLKQALLGHTDTVTCATASLAY 3139
Query: 3494 SLIVSGSKDRTVIFWDLSSLEYVRQLPELPDPPTAIHANDMTGEVVTASGTTLSVWSING 3553
+IVSGS+DRT I WDL+ L ++ QL P +A+ N++TG++V+ +GT + VWSING
Sbjct: 3140 HIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSING 3199
Query: 3554 DCLAAVNTSHVAADTILSITSPHLSDWMEASWYVTGHQNGVIRLWHMEL 3602
+ + +VNT + I+ +++W + VTGH +GV+R W ME
Sbjct: 3200 NPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEF 3248
Score = 125 bits (313), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 114/418 (27%), Positives = 183/418 (43%), Gaps = 48/418 (11%)
Query: 1168 GDRAWPPTAGYSFVCWARFEKLTQSGPNTNGAEATKESNRNRSGS-----LGSVL----R 1218
G+R +PP +G S+ W E + S PN + R S L VL R
Sbjct: 1090 GERFFPPPSGLSYSSWFCIEHFS-SPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDR 1148
Query: 1219 IFTVGTAEEKSTVCAELFLSDSGVLTLATSPTSYVCFKGVRLEEGIWYHLTIVHNKPNAL 1278
V T EE + F +S + + C G + EG W+HL +V +K
Sbjct: 1149 SLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRC--GELIIEGQWHHLVLVMSK---- 1202
Query: 1279 AGLFQSSVAHLYLNGSLRHTGKLGYSAS----------PTEKSLQVTIGTPPSFSEVSPL 1328
G+ ++S A LY++G L +T KL Y S P ++ IGTPP+ +++ L
Sbjct: 1203 -GMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASL 1261
Query: 1329 TWQLGSCYLFEEVLPAPAIFFMYVLGRGYRGLFQDTDLLQFIPYEACGGGNLMVLESLDT 1388
W+LG + EEVLP+ + +Y LG Y G FQ C E +
Sbjct: 1262 VWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQ----------AVCMPCKDAKSEGVVP 1311
Query: 1389 ELLASLRAEGVSQSAGVALSEGSGVIWDLEKLARFWAQLCGRHLIFAYDGSNAENVVPAG 1448
++ + E VS ALS S + + K+ + +L + + S+ EN P
Sbjct: 1312 SPVSLVPEEKVSFGL-YALSVSSLTVARIRKV---YNKLDSKAIAKQLGISSHENATPVK 1367
Query: 1449 AISIVNLVDPMSAAASVLGGLPRLARI-YGDVHICTPCNIADSMRKVGGVAVVLAMIEAA 1507
I N ++ +A +G A I Y V P +A +++ VGG A +L ++ A
Sbjct: 1368 LIH--NSAGHLNGSARTIGA----ALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMA 1421
Query: 1508 DTCETLHLALSVLVSMLQSNPRNARDMQACRGYHLLALFLHRRMDCFEARDLDFLFRI 1565
E L+ A+ LV +++SNP +++M+ +GY LLA+ L ++ + L F +
Sbjct: 1422 SDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSL 1479
Score = 68.6 bits (166), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 71/302 (23%), Positives = 126/302 (41%), Gaps = 19/302 (6%)
Query: 588 IRDIEIVQTFQDIFLKTGNXXXXXXXXXXXXXXFASHPDNYVLVQELRTMPLFLQNMGKY 647
+R+++ Q+ FLK + + NY +++ T+ F + + K
Sbjct: 378 VRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISK- 436
Query: 648 LLILQERLLKVLEYAVTVVNCVPEQELLSLCYLLQQPYESSLRKIVLTFFEKLLSFDRNY 707
L +Q + ++LE+ V +N +P +EL+S+ LL+ I + K D +
Sbjct: 437 LPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIF 496
Query: 708 KKVLREVGXXXXXXXXXRRCGLSEVSAFKNSSEPL-VKSPSRELCIFEDMVTVG-LTWDC 765
K V REVG + + K+ ++ L + SR ED + L +
Sbjct: 497 KDVFREVGLLEVMVNLLHKYA----ALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMET 552
Query: 766 LLSLLKKSDGNQTVFRKANGVGYILPLVASASQRSGALRVLSCLICEDVNQAHADELKSL 825
L LL+ S+ N +FR+ G +V R AL + L+ ++ D++ +L
Sbjct: 553 LTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLV---LSPNGDDDMGTL 609
Query: 826 LKIAHSGIVYGQNGLPIGLDTEGKEDILWAVWRILGANFTTRVVFGDGNGFGLLLSVLEG 885
L + HS P L K DIL A+ +L + +R VF GF + S+L
Sbjct: 610 LGLMHSAP-------PTELQL--KTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVA 660
Query: 886 IQ 887
++
Sbjct: 661 ME 662
Query: CNT0034414
Subject: sp|Q7LKZ7|BPH1_SCHPO Beige protein homolog 1 OS=SchizosaccharomycesOS=Mus musculus GN=Wdfy3 PE=1 SV=1
Score = 617 bits (1590), Expect = e-176, Method: Compositional matrix adjust.
Identities = 371/1003 (36%), Positives = 544/1003 (54%), Gaps = 113/1003 (11%)
Query: 2627 LELVREAMAAELRVLRQDKYGWILHAENGWANHLQQLVHERGIW--PIVSEVRDEEPDWQ 2684
+ +VR+ + + + ++ + + + W +L+ ERG+W PI S + W
Sbjct: 2314 IAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDK----WM 2369
Query: 2685 LCPTEGPYXXXXXXXXXXXXISVFEKSQLMVERETEALDRCTPIDVINPSDKENALHNQY 2744
L TEGP + + E E EA V P+ A+
Sbjct: 2370 LEMTEGPCRMRKKMVRNDM---FYNHYPYVPETEQEA-------SVGKPARYRRAI---- 2415
Query: 2745 VDIFNFDTQKRLGYSSKEFLVSLEE-DISELKNEIGEEEE-DVLSARVDWNEEPFPSGSE 2802
Y SKE+ + L + + +++ I E E + + E+
Sbjct: 2416 ------------SYDSKEYYLRLASGNPAIVQDAIVESSEGEATQQEPEHGEDTIAKVKG 2463
Query: 2803 SQVPKAMSVASLKLAGEEVTDQTLGSSQGRGSPAEKDVPEEANYLEQEMHEDGEYLIRPH 2862
P S G+E T + L +D E+ +E+E D L+R
Sbjct: 2464 LVKPPLKRSRSAPDGGDEETQEQL-----------QDQIAESGSIEEEEKTDNATLLR-L 2511
Query: 2863 LEPGERIRFRYNCERVVGLDKRDGIFLIGEKCLYVIENYIIDENKCIKEKGEERDLSVID 2922
LE GE+I+ Y C RV GLD +G+ L G++ YVI+ + + + E RD+ +
Sbjct: 2512 LEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATR------EIRDIETLP 2565
Query: 2923 RALGVRANSARVVDTHSSKQGEVVADSWPGGRAWAYSGGAWGKEKVKAGQNMPHPWRMWK 2982
N + ++QG + ++
Sbjct: 2566 ------PNMHEPIIPRGARQGP---------------------------SQLKRTCSIFA 2592
Query: 2983 LESVHELLKRRYQLRPVAIELFSMDGCNDLLVFHKNERDEVFKNLLAMNLPRNSMLDTTI 3042
E + E+ KRRY L+P+A+E+FS DG N LL F K R++V++ LA+ +P S+ D++
Sbjct: 2593 YEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAV-VP--SLTDSSE 2649
Query: 3043 SAASKQ-----EAGEGGRLFKMMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYNDLTQYP 3097
S + ++ E G G + KS ++RW+ GEISNFQYLMHLNTLAGR YNDL QYP
Sbjct: 2650 SVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYP 2709
Query: 3098 VFPWILKDYTSEELDLSNPDTFRRLDKPMGALHPEREKEFRKRYETWEDP--EIPRFHYG 3155
VFPWIL DY SEE+DL+NP TFR L KPMGA ER +++KRY+ WEDP E P +HYG
Sbjct: 2710 VFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYG 2769
Query: 3156 SHYSSAGSVLFYLIRLPPFSQENKQLQGGSFDHSDRLFNSIKDTWLSASQGNTADVKELI 3215
+HYSSA V YL+R+ PF+Q +LQGG FD +DR+F+S+++ W SAS+ N ADVKELI
Sbjct: 2770 THYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELI 2829
Query: 3216 PEFFYLPEFLENRFGFDFGTKQSGEKVNDVLLPPWAKGSAREFVRKHREALESQYVSENL 3275
PEFFYLPEFL N FD G KQ+G K+ DV+LPPWAKG REF+R HREALE YVS +L
Sbjct: 2830 PEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHL 2889
Query: 3276 HHWIDLIFGFKQRGKPAVEALNVFYYLTYEGAVDIDRVPDPGMKAAILAQINHFGQTPKL 3335
H WIDLIFG+KQ+G AVEA+NVF++L YEG VDI + DP + A + IN+FGQ PK
Sbjct: 2890 HEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQ 2949
Query: 3336 LFTKPHSKRK----------WVQKQPLALALRNY--HL--LAPQ--EMRPLSSRVSQIVI 3379
LF KPH ++ + P A + + + HL L P ++ L V QIV
Sbjct: 2950 LFKKPHPPKRVRSRLNGDNIGISVPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVC 3009
Query: 3380 FQDKVYAAGANRILKPPSYSKYLSWGFSDRSLRIVSYDQERLLSTHENLHDDGPVLCAGF 3439
+ A N++L PP+++K +WG++D S R+ +Y+ ++ ++ +E L + G +LCA
Sbjct: 3010 TDKGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCA-V 3068
Query: 3440 SRDGRILVTGGSDGVVSVWRQRKDGLRGQRRLHLQKSLCAHTQSVICLAVSQPYSLIVSG 3499
+ ++++TGG+ VV VW + + L L+++L HT +V C S Y +IVSG
Sbjct: 3069 CPNPKLVITGGTSTVVCVWEMGTSKEKA-KPLTLKQALLGHTDTVTCATASLAYHIIVSG 3127
Query: 3500 SKDRTVIFWDLSSLEYVRQLPELPDPPTAIHANDMTGEVVTASGTTLSVWSINGDCLAAV 3559
S+DRT I WDL+ L ++ QL P +A+ N++TG++V+ +GT + VWSING+ + +V
Sbjct: 3128 SRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSV 3187
Query: 3560 NTSHVAADTILSITSPHLSDWMEASWYVTGHQNGVIRLWHMEL 3602
NT + I+ +++W + VTGH +GV+R W ME
Sbjct: 3188 NTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEF 3230
Score = 127 bits (318), Expect = 3e-27, Method: Compositional matrix adjust.
Identities = 112/418 (26%), Positives = 182/418 (43%), Gaps = 48/418 (11%)
Query: 1168 GDRAWPPTAGYSFVCWARFEKLTQSGPNTNGAEATKESNRNRSGS-----LGSVL----R 1218
G+R +PP +G S+ CW E + S PN + R S L VL R
Sbjct: 1090 GERFFPPPSGLSYSCWFCIEHFS-SPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDR 1148
Query: 1219 IFTVGTAEEKSTVCAELFLSDSGVLTLATSPTSYVCFKGVRLEEGIWYHLTIVHNKPNAL 1278
V T EE + F +S + + C G + EG W+HL ++ ++
Sbjct: 1149 SLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRC--GELVVEGQWHHLALLMSR---- 1202
Query: 1279 AGLFQSSVAHLYLNGSLRHTGKLGYSAS----------PTEKSLQVTIGTPPSFSEVSPL 1328
G+ ++S A LYL+G L T KL Y S P ++ +GTPP+ +++ L
Sbjct: 1203 -GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASL 1261
Query: 1329 TWQLGSCYLFEEVLPAPAIFFMYVLGRGYRGLFQDTDLLQFIPYEACGGGNLMVLESLDT 1388
W+LG + EEVLP ++ +Y LG Y G FQ +P + + T
Sbjct: 1262 VWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAV----CVPCKDAKSEGV-------T 1310
Query: 1389 ELLASLRAEGVSQSAGVALSEGSGVIWDLEKLARFWAQLCGRHLIFAYDGSNAENVVPAG 1448
SL AE ALS S + + K+ + +L + + S+ EN P
Sbjct: 1311 PSPVSLVAEEKVSFGLYALSVSSLTVARIRKV---YNKLDSKAIAKQLGISSHENATPVK 1367
Query: 1449 AISIVNLVDPMSAAASVLGGLPRLARI-YGDVHICTPCNIADSMRKVGGVAVVLAMIEAA 1507
+ N ++ A +G A I Y V P +A +++ +GG A +L ++ A
Sbjct: 1368 LVH--NAAGHLNGPARTIGA----ALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMA 1421
Query: 1508 DTCETLHLALSVLVSMLQSNPRNARDMQACRGYHLLALFLHRRMDCFEARDLDFLFRI 1565
E L+ A+ LV +++SNP +++M+ +GY LLA+ L ++ + L F +
Sbjct: 1422 SDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSL 1479
Score = 75.1 bits (183), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 3/112 (2%)
Query: 3647 HKKPVTALSLGNDLKQLCSGDAGGHLVSWTLPDDGFKQTPSLEIEP---DQCTTCQKELD 3703
H VTAL + D ++ GD+ G + SW++ D + ++ D C+ C
Sbjct: 3391 HPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFS 3450
Query: 3704 TPEKKHHCRNCGQISCADCCNNHIVLEDLGYFSPVRVCGSCCESRQSSTGRQ 3755
E++HHCRNCGQ+ C C ++ L SPVRVC +C S Q G +
Sbjct: 3451 LTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAE 3502
Score = 69.7 bits (169), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 72/302 (23%), Positives = 125/302 (41%), Gaps = 19/302 (6%)
Query: 588 IRDIEIVQTFQDIFLKTGNXXXXXXXXXXXXXXFASHPDNYVLVQELRTMPLFLQNMGKY 647
+R+I+ Q+ FLK + + NY +++ T+ F + + K
Sbjct: 378 VRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISK- 436
Query: 648 LLILQERLLKVLEYAVTVVNCVPEQELLSLCYLLQQPYESSLRKIVLTFFEKLLSFDRNY 707
L +Q + ++LE+ V +N +P +EL+S+ LL+ I + K D +
Sbjct: 437 LPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIF 496
Query: 708 KKVLREVGXXXXXXXXXRRCGLSEVSAFKNSSEPL-VKSPSRELCIFEDMVTVG-LTWDC 765
K V REVG + + K+ ++ L + SR ED + L +
Sbjct: 497 KDVFREVGLLEVMVNLLHKYA----ALLKDPAQALNEQGDSRNNSSVEDQKHLALLVMEA 552
Query: 766 LLSLLKKSDGNQTVFRKANGVGYILPLVASASQRSGALRVLSCLICEDVNQAHADELKSL 825
L LL+ S+ N +FR+ G +V R AL + L+ + D++ +L
Sbjct: 553 LTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGE---DDMGTL 609
Query: 826 LKIAHSGIVYGQNGLPIGLDTEGKEDILWAVWRILGANFTTRVVFGDGNGFGLLLSVLEG 885
L + HS P L K DIL A+ +L + +R VF GF + S+L
Sbjct: 610 LGLMHSAP-------PTELQL--KTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVA 660
Query: 886 IQ 887
++
Sbjct: 661 ME 662
Query: CNT0034414
Subject: sp|Q6ZS81|WDFY4_HUMAN WD repeat- and FYVE domain-containing protein 4pombe (strain 972 / ATCC 24843) GN=lvs1 PE=1 SV=2
Score = 490 bits (1262), Expect = e-138, Method: Compositional matrix adjust.
Identities = 315/925 (34%), Positives = 478/925 (51%), Gaps = 102/925 (11%)
Query: 2863 LEPGERIRFRYNCERVVGLDKRDGIFLIGEKCLYVIENYIIDENKCIKEKGEERDLSVID 2922
+E G+ I+ YN R+ GL+ +GI L+G++ LY+++N+ + + E + D S+ID
Sbjct: 1734 IESGDSIQDVYNVSRIFGLEATEGILLLGKQYLYLMDNFFLRSDN---EIVDVNDNSIID 1790
Query: 2923 RALGVRANSARVVDTHSSKQGEVVADSWPGGRAWAYSGGAWGKEKVKAGQNMPHPWRMWK 2982
D + S KV+ + + W W
Sbjct: 1791 ER-----------DPYLQLLHLQSLSS---------------SGKVRRHISKENNWH-WD 1823
Query: 2983 LESVHELLKRRYQLRPVAIELFSMDGCNDLLVF-HKNERDEVFKNLLA----MNLPRNSM 3037
+ +LKR Y LR V +ELF DG + L + + RD +++ L+A ++ S
Sbjct: 1824 FIDLSLVLKRFYLLRDVGLELFFKDGRSFLTILSNTKNRDSLYQKLVARAPGADVLSTSH 1883
Query: 3038 LDTTISAASKQEAGEGGRLFKMMAKSFS--------KRWQNGEISNFQYLMHLNTLAGRG 3089
T++S + G+ L +A + S KRW+ EISNF YL +NTLAGR
Sbjct: 1884 FATSMSRDLGKANGKSNFLSSKLANALSFSTTHPATKRWERREISNFNYLQIVNTLAGRT 1943
Query: 3090 YNDLTQYPVFPWILKDYTSEELDLSNPDTFRRLDKPMGALHPEREKEFRKRYETW---ED 3146
YNDLTQYPVFPW++ DYTS+ELDL+NP T+R KPMGA HPERE +F +RY+ D
Sbjct: 1944 YNDLTQYPVFPWVIADYTSKELDLNNPKTYRNFCKPMGAQHPERESQFNERYDLLLGLND 2003
Query: 3147 PEIPRFHYGSHYSSAGSVLFYLIRLPPFSQENKQLQGGSFDHSDRLFNSIKDTWLSASQG 3206
+ FHYG+HYSSA V YLIRL PF LQGG FDH+DRLF SI+ W S+S+
Sbjct: 2004 SQQQPFHYGTHYSSAMIVCSYLIRLRPFVDSYLALQGGQFDHADRLFYSIEQAWRSSSKE 2063
Query: 3207 NTADVKELIPEFFYLPEFLENRFGFDFGTKQS-GEKVNDVLLPPWAKGSAREFVRKHREA 3265
N ADV+ELIPEFFYL E N GFDFG++Q +NDV+LPPWAKG FV+K+REA
Sbjct: 2064 NMADVRELIPEFFYLSEMFINGNGFDFGSRQKESTPINDVILPPWAKGDPAIFVQKNREA 2123
Query: 3266 LESQYVSENLHHWIDLIFGFKQRGKPAVEALNVFYYLTYEGAVDIDRVPDPGMKAAILAQ 3325
LES+YVS +LH WIDL+FG KQRG AV A NVF++L+Y+GA+D++ + + AA +
Sbjct: 2124 LESKYVSAHLHEWIDLVFGCKQRGDEAVAATNVFHHLSYQGAIDLENIENEFELAAAVGI 2183
Query: 3326 INHFGQTPKLLFTKPHSKR-KWVQKQPLALAL-----RNYHLLAPQEMRPLSSRVSQIVI 3379
I++FGQTPK +F KPH +R PL L + HLL Q P+ ++
Sbjct: 2184 IHNFGQTPKQVFKKPHPQRGPDFTDTPLGPYLFGRFEDSIHLLF-QSCSPIIRICKKVAH 2242
Query: 3380 FQ-----DKVYAAGANRILKPPSYSKYLSWGFSDRSLRIVSYDQERLLSTHENLHDDGPV 3434
Q D+V A A+ P + +L+WG D +++++S ++ E LH +
Sbjct: 2243 IQYDPSKDEVGAFAAD--YTPLGPNTFLAWGRVDNTVQLISDQLDKQPVMFEELHSEK-- 2298
Query: 3435 LCAGFSRDGRILVTGGSDGVVSVWRQRKDGLRGQRRLHLQKSLCAHTQSVICLAVSQPYS 3494
+ + D R +T D + +W + + L++ L H + C+ V + +S
Sbjct: 2299 ITHVVACDERTFLTASLDLTLRLWTLSTN---KPIKASLKRVLYGHRYRITCVTVCKAFS 2355
Query: 3495 LIVSGSKDRTVIFWDLSSLEYVRQLPELPDPPTAIHANDMTGEVVTASGTTLSVWSINGD 3554
+IVSG +I WDL+ E+V L P I N E+ ++G V ++NG
Sbjct: 2356 IIVSGDAGGNLIIWDLNRAEFVSSLSVYKLPIQTIAVNARNAEIAFSTGFYCCVVNVNGK 2415
Query: 3555 CLAAVNTSHV----AADTIL--SITSPHLSDWMEASWYVTGHQNGVIRLWHMELDNHSKL 3608
L S + + + IL + S+W+ + ++TGH +G+IR+W L +++KL
Sbjct: 2416 ILVKDKLSRIYNENSDENILCSCFYTGANSEWLHKNLFITGHPDGIIRIWEKRLQSNAKL 2475
Query: 3609 DRKASHRISDSWGLNMSKSCITGGPPEYQLVLYKVLSWH----KKPVTALSLGNDLKQLC 3664
+ + ++ W ++ + QL K L + ++ + ++ + +
Sbjct: 2476 EAEKNNADRPKWRFHLLR----------QLQHTKGLGRNRVATRQNIITITPNGQARGIF 2525
Query: 3665 SGDAGGHLVSWTLPDDGFKQTPSLEIEPDQ----CTTCQKELDTPEKKHHCRNCGQIS-C 3719
+GD G + SW LPD T ++ +E D C+ C E + CR CG + C
Sbjct: 2526 AGDDKGQVFSWMLPD----TTSNVHLEKDNTSELCSLCDSRFSLMEWRSQCRACGNSNVC 2581
Query: 3720 ADCCNNHIVLEDLGYFSPVRVCGSC 3744
+DC + +L+D + ++ C C
Sbjct: 2582 SDCVS---MLKD----TNIKTCYEC 2599
Query: CNT0034414
Subject: sp|Q86JF2|LVSB_DICDI BEACH domain-containing protein lvsBOS=Homo sapiens GN=WDFY4 PE=1 SV=3
Score = 489 bits (1259), Expect = e-137, Method: Compositional matrix adjust.
Identities = 280/736 (38%), Positives = 404/736 (54%), Gaps = 67/736 (9%)
Query: 2986 VHELLKRRYQLRPVAIELFSMDGCNDLLVFHKNERDEVFKNLLAMNLPRNSMLDTTISAA 3045
+ EL + R+ L+ +A+E+F +G + LVF+ N+R + FK+ + ++
Sbjct: 2468 MRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQ--------PSLKGK 2519
Query: 3046 SKQEAGEGGRLFKMMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYNDLTQYPVFPWILKD 3105
+ E R + + ++WQ +ISNF+YLM+LNT AGR ND QYPVFPW+L D
Sbjct: 2520 ATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLAD 2579
Query: 3106 YTSEELDLSNPDTFRRLDKPMGALHPEREKEFRKRYETWEDPE---IPRFHYGSHYSSAG 3162
YTSE L+L+NP FR L KPMGA ER+ +F +R++ E E + HY +HYSSA
Sbjct: 2580 YTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAI 2639
Query: 3163 SVLFYLIRLPPFSQENKQLQGGSFDHSDRLFNSIKDTWLSASQGNTADVKELIPEFFYLP 3222
V YL+R+PPF+Q LQGGSFD +DR+F+S+K TW SAS+ N +DV+EL PEFFYLP
Sbjct: 2640 IVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESASRENMSDVRELTPEFFYLP 2699
Query: 3223 EFLENRFGFDFGTKQSGEKVNDVLLPPWAKGSAREFVRKHREALESQYVSENLHHWIDLI 3282
EFL N G +FG Q G + DV LPPWA G R+F+ HR+ALES +VS NLHHWIDLI
Sbjct: 2700 EFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLI 2759
Query: 3283 FGFKQRGKPAVEALNVFYYLTYEGAVDIDRVPDPGMKAAILAQINHFGQTPKLLFTKPHS 3342
FG+KQ+G AV+A+N+F+ Y +D+ + DP +K+ IL +++FGQ PK LFTKPH
Sbjct: 2760 FGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHP 2819
Query: 3343 KRKWVQK---------------------------QPLALALRNYHLLAPQEMRPLSSRVS 3375
R K +P + +++ +L + P + +
Sbjct: 2820 ARTAAGKPLPGKDVSTPVSLPGHPQPFFYSLQSLRPSQVTVKDMYLFSLGSESPKGA-IG 2878
Query: 3376 QIVIFQDKVYAAGANRILKPPSYSKYLSWGFSDRSLRIVSYDQERLLSTHENLHDDGPVL 3435
IV + + A N++L PP +++ SWGF D S + SY +++L T ENL G L
Sbjct: 2879 HIVSTEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGRCL 2938
Query: 3436 CAGFSRDGRILVTGGSDGVVSVWRQRKDGLRGQRRLHLQKSLCAHTQSVICLAVSQPYSL 3495
CA +VT G+ VV VW R R L L+++L HTQ+V CLA S +SL
Sbjct: 2939 CA-VCPSPTTIVTSGTSTVVCVWELSMTKGR-PRGLRLRQALYGHTQAVTCLAASVTFSL 2996
Query: 3496 IVSGSKDRTVIFWDLSSLEYVRQLPELPDPPTAIHANDMTGEVVTASGTTLSVWSINGDC 3555
+VSGS+D T I WDL L +V +LP + +AI +D++G +V+ +G LS+W++NG
Sbjct: 2997 LVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNGQP 3056
Query: 3556 LAAVNTSHVAADTILSITSPHLSDWMEASWYVTGHQNGVIRLWHMELDNHSKLDRKASHR 3615
LA++ T+ I W + +TG Q+G++R+W E S R A
Sbjct: 3057 LASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSVPGRPAGEE 3116
Query: 3616 I--------SDSWGLNMSKS-------CITGGPPEYQLVLYKVLSWHKKPVTALSLGNDL 3660
W N++ S +TG P S VTAL++ +
Sbjct: 3117 PPAQPPSPRGHKWEKNLALSRELDVSIALTGKP-----------SKTSPAVTALAVSRNH 3165
Query: 3661 KQLCSGDAGGHLVSWT 3676
+L GD G + W+
Sbjct: 3166 TKLLVGDERGRIFCWS 3181
Score = 68.2 bits (165), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 106/470 (22%), Positives = 174/470 (37%), Gaps = 102/470 (21%)
Query: 1151 IEFRMSRIGHACIRTPL--------------------GDRAWPPTAGYSFVCWARFEKLT 1190
+EF MS G+ C+ P R +PP G +F CW
Sbjct: 1023 VEFDMSVEGYGCLFIPTLSTVMGTSTEYSVSGGIGTGATRPFPPPGGLTFSCWFLI---- 1078
Query: 1191 QSGPNTNGAEATKESNRNRSGSLGSVLRIFTVG---TAEEKSTVCAELFLS-DSGVLTLA 1246
+R+ + + G LR T+ E+ VC + L D L ++
Sbjct: 1079 ---------------SRHGAATEGHPLRFLTLVRHLARTEQPFVCFSVSLCPDDLSLVVS 1123
Query: 1247 T----------------SPTSYVCFKGVR----LEEGIWYHLTIVHNKPNALAGLFQSSV 1286
T S S C VR L G W+HL +V K + +
Sbjct: 1124 TEEKEFQPLDVMEPEDDSEPSAGCQLQVRCGQLLACGQWHHLAVVVTKE-----MKRHCT 1178
Query: 1287 AHLYLNGSLRHTGKLGY---------SASPTE-KSLQVTIGTPPSFSEVSPLTWQLGSCY 1336
L+G + + K+ Y S P+ + I TP + + S L W+LG Y
Sbjct: 1179 VSTCLDGQVIGSAKMLYIQALPGPFLSMDPSAFVDVYGYIATPRVWKQKSSLIWRLGPTY 1238
Query: 1337 LFEEVLPAPAIFFMYVLGRGYRGLFQDTDLLQFIPYEACGGGNLMVLESLDTELLASLRA 1396
LFEE + + + LG Y G FQ + E LD+E +
Sbjct: 1239 LFEEAISMETLEVINKLGPRYCGNFQAVHVQG---------------EDLDSEATPFVAE 1283
Query: 1397 EGVSQSAGVALSEGSGVIWDLEKLARFWAQLCGRHLIFAYDGSNAENVVPAGAISIVNLV 1456
E VS +A S I + + + ++ R + + S+ +N +P + N
Sbjct: 1284 ERVSFGLHIA----SSSITSVADIRNAYNEVDSRLIAKEMNISSRDNAMP--VFLLRNCA 1337
Query: 1457 DPMSAAASVLGGLPRLARIYGDVHICTPCNIADSMRKVGGVAVVLAMIEAADTCETLHLA 1516
+S + +G + + ++ V +P A S+ +GG A++L +I A T++ A
Sbjct: 1338 GHLSGSLRTIGAV-AVGQLGVRVFHSSPA--ASSLDFIGGPAILLGLISLATDDHTMYAA 1394
Query: 1517 LSVLVSMLQSNPRNARDMQACRGYHLLALFLHRRMDCFEARDLDFLFRIA 1566
+ VL S+L SN MQ GY ++A L ++ R + +A
Sbjct: 1395 VKVLHSVLTSNAMCDFLMQHICGYQIMAFLLRKKASLLNHRIFQLILSVA 1444
Score = 53.9 bits (128), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 126/582 (21%), Positives = 223/582 (38%), Gaps = 97/582 (16%)
Query: 582 PDLEG----------RIRDIEIVQTFQDIFLKTGNXXXXXXXXXXXXXXFASHPDNYVLV 631
P LEG +++++ Q Q++F K + +A + N+ L+
Sbjct: 364 PQLEGFKFHHEASGVTVKNLQAFQVLQNVFHKASDSVLCIQVLSVIRTMWAWNARNFFLL 423
Query: 632 Q-ELRTMPLFLQNMGKYLLILQERLLKVLEYAVTVVNCVPEQELLSLCYLLQQPYESSLR 690
+ L+ + F++ M +QE ++LE V ++ VP + L + +L+++ S
Sbjct: 424 EWTLQPISQFVEIMPLKPAPVQEHFFQLLEALVFELHYVPHEILRKVQHLIKESPGPSCT 483
Query: 691 KIVLTFFEKLLSFDRNYKKVLREVGXXXXXXXXXRRCGLSEVSAFKNSSEPLVKSPSREL 750
+ L + D + + R+ G R+ + S P V+ P REL
Sbjct: 484 LMALQSILSIAGGDPLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKVSTPGVQDPEREL 543
Query: 751 -CIFEDMVTVGLTWDCLLSLLKKSDGNQTVFRKANGVGYILPLVASASQRSGALRVLSCL 809
C+ +V ++LLK S N V + V +I + R +L +L
Sbjct: 544 TCVMLRIV---------VTLLKGSVRNAVVLKDHGMVPFIKIFLDDECYREASLSIL--- 591
Query: 810 ICEDVNQAHADELKSLLKIAHSGIVYGQNGLPIGLDTEGKEDILWAVWRILGANFTTRVV 869
E ++ +A+E S++ A G+ L + L RIL R
Sbjct: 592 --EQLSAINAEEYMSIIVGALCSSTQGELQLKLDLLKSLL--------RIL-VTPKGRAA 640
Query: 870 FGDGNGFGLLLSVLEGIQSRHENSSAESVADEAAFVPNLTEHMEVLDALLHVVTVGAAEY 929
F +GF LLS+L ++ + ++ A P T +E++ L V+
Sbjct: 641 FRVSSGFNGLLSLLSDLEGSLQEPPLQAW---GAVSPRQT--LELVLYTLCAVSAALHWD 695
Query: 930 PPN-----RNKLHECISSQ-----TFKRLLQTSGLLCSDFEEKVAERLFDVALERVLSPS 979
P N RN L E ++ F L + LL S + K R F L S S
Sbjct: 696 PVNGYFFRRNGLFEKLAEDLCLLGCFGALEEEGNLLRSWVDTKA--RPFADLLGTAFSSS 753
Query: 980 -------QSALGL----------PILLQGDGTKSFRIPGA--------------EKDFPV 1008
QS L + + L+GD +S R +++F
Sbjct: 754 GSLPPRIQSCLQILGFLDSMASGTLHLRGDLKESLRTKQGPVVDVQKGETGSDPQRNFKQ 813
Query: 1009 NPGQIAQID-----VYNPGAIAVLLFFL--------PQFSAKLQLRILIQVERIVSKSPW 1055
P ++D + +PG + +++ L PQ S ++Q + ++ +V KS
Sbjct: 814 WPDLEERMDEGDAAIMHPGVVCIMVRLLPRLYHEDHPQLSEEIQCSLASHIQSLV-KSEK 872
Query: 1056 NQNALTSAGCVGDLLEAVKSMMQTKPSPLLSYSLKIVEVLGS 1097
N+ + AG +G L+ + + T SPL S ++I E L S
Sbjct: 873 NRQVMCEAGLLGTLMASCHRALVTSGSPLHSRLIRIFEKLAS 914