Score =  725 bits (1871), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 564/2079 (27%), Positives = 979/2079 (47%), Gaps = 258/2079 (12%)

Query: 1281 LRSKHAEQQVGTVMALNFCLALRPPLLKMR---QELSNILQESLQIAEADESVLNGKFMN 1337
            LR + A  Q+G +    FC  L+P L  M     E      E L + EA++S L  K   
Sbjct: 15   LRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDSALT-KLPC 73

Query: 1338 PKMAATLTKLRTVCIELLCTAMAWADFKTQSHAELRSRIIAMFFKSLTCRTPEIVAVAKE 1397
             K   +L  LR   +  L        +  QS    R +IIA  FK+L     E+    + 
Sbjct: 74   YKSLPSLVPLRIAALNALAACN----YLPQS----REKIIAALFKALNSTNSELQEAGEA 125

Query: 1398 GLRQVIQQQKMPKELLQSSLRPILVNLAHYKNLTMPXXXXXXXXXXXXSNWFNVTLGEKL 1457
             +R+ ++   +  + + + +RP+L+ L  Y++LT+              N FN    +++
Sbjct: 126  CMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQM 185

Query: 1458 MEHLKKWLEPEKLSSSQKSWKAGEEPKIAGAIIELFHLLPPAAQKFLDQLVTLTMQLEAA 1517
            M+HL+KW+E   ++        G E KI  AII LFHL+P A Q  +   + + M+ E A
Sbjct: 186  MQHLRKWMEVVVITHKGGQRSDGNEMKICSAIINLFHLIPAAPQTLVKPPLEVVMETERA 245

Query: 1518 LPPSQVYSELNSPYRLPLTKFLNRYAPEAVDYFL--GRLTQPTVFRRFMDIIQSEGGQPL 1575
            +       E  SP+R PL KFL R+  + V+ F+    L  P   R FM  ++ +  +PL
Sbjct: 246  M-----LIEAGSPFREPLIKFLTRHPSQTVELFMMGATLNDPQWSRMFMSFLKHKDARPL 300

Query: 1576 REELARSPNKIIQSAFPAVEENXXXXXXXXXXXXXXXXXXXXXQATAEAQFQGVALVSAL 1635
            R+ LA +PN+ I    P   +                          + QFQ + ++S +
Sbjct: 301  RDVLAANPNRFITLLLPGGAQTAVRPGSSSTSNMRL-----------DLQFQAIKIISII 349

Query: 1636 VKLLPDWLHQNRAVFDALVRLWQSPARQARLINEQGLSLNQVKESKRLVKCFLNYLRHDK 1695
            VK    WL    ++   L R+W S   Q R   E   + N  KE K L  C LNY + + 
Sbjct: 350  VKNDDAWLASQHSLVSQLRRVWVSETFQERHRKENMAATNW-KEPKLLAFCLLNYCKRNY 408

Query: 1696 AEVNVLFEMLSIFLVRTRIDYTFLKEFYMVEVGEGYSPQEKKAVLLCFLELFQTKRLPQD 1755
             ++ +LF++L  F  R   + TFLKE+   E+ + YS  +K+A+   F+E F       +
Sbjct: 409  GDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFVE-FNDPNFGDE 467

Query: 1756 VLVVAMQMLILPMLTHSFQQNQCWDVVD---------ATIIKTIIEKLLDPPEEVSADYD 1806
            +    +Q ++ P   +SF++ +   ++           +I    I K+LDP  E  AD  
Sbjct: 468  LKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDP--EKQADML 525

Query: 1807 ESXXXXXXXXXXXXXXXXPSDLVHHRK-------ELIKFGWNHLKRE---ESASKQWAFV 1856
            +S                P  +  + K        L+ F W  L  +   + A +    +
Sbjct: 526  DSLRIYLLQYATLLVEHAPHHIHDNNKNRNSKLRRLMTFAWPCLLSKACVDPACRYSGHL 585

Query: 1857 NVCQFLEAYQAPEKIILQVFVALLRTCQPEHRVLVKQALDILMPALPRRLPLGENKIPIW 1916
             +   +  +   +KI+LQVF +LL+    E R +V+QA+ IL PA+P R+  G   +  W
Sbjct: 586  LLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDGHQMLTHW 645

Query: 1917 IRYTKKILVEEGHSVPNLIHIFQLLVRHANLFYNCRAQFVPQMVNSLSRLGLPQNTPLEN 1976
               T+KI+VEEGH+VP L+HI   +V+H  ++Y  R   V  MV+++ RLG   +  +E 
Sbjct: 646  ---TRKIIVEEGHTVPQLVHILHPIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSVTIEQ 702

Query: 1977 RRLAIDLAGLVVMWEKRRQAEAKGSSTEGDGQSKSAGAEGQVPAEAIAAGGAPSGTKRTA 2036
            RRLA+DL+ +V+ WE +R    K    + D    S+G                 G    +
Sbjct: 703  RRLAVDLSEVVIKWELQR---IKDQQPDSDMDPNSSG----------------EGVNSVS 743

Query: 2037 EAAGLTGVGDEASKRTKSESG-LPGLAGMSPNLPTGPTNSIPNIGTPGSMGQADEEFKPN 2095
               GL+    +  KR ++ +G +  + G S +LP    +S+  +  P      D      
Sbjct: 744  IKRGLSVDSAQEVKRFRAATGAISAVFGRSQSLPGA--DSL--LAKPIDKQHTD------ 793

Query: 2096 AAMEEMIINFLIRVALV----TEPKDKETQAMYKQALELLTQAL--EVWPHANVKFNYLE 2149
                  ++NFLIRVA      T       + + ++ + LL  AL  ++W  + +K  + +
Sbjct: 794  -----TVVNFLIRVACQVNDNTNTAGSPGEVLSRRCVNLLKTALRPDMWCKSELKLQWFD 848

Query: 2150 KIL-SAQQPAGQSKDPATALAQGLDVMNKAVEKQPHLFIRNNVHHIIQVLEPSFNCKLPE 2208
            K+L + +QP   ++     +  GL+V+N  +       I ++   + + +     C   +
Sbjct: 849  KLLMTVEQP---NQVNYGNICTGLEVLNFLLTVLQSPAILSSFKPLQRGIAACMTCGNTK 905

Query: 2209 IGNSLCTLLKMVFEAFPVDASDT-----HQDVKLLHQKVEELIQKQLTT----VTSNPTQ 2259
            +  ++ +LL  +   FP + S +     +++++ L+  V ++I + LT      ++NP+Q
Sbjct: 906  VLRAVHSLLSRLMSIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATSANPSQ 965

Query: 2260 PPVEASVINVMISFTLNVLKTLVAGNKQYVDKFMLYLVRVFHRLAREMATTSAQLARQQG 2319
                       +  TL + K+    N  Y+D+ +   +R   ++ RE       L  Q  
Sbjct: 966  -----------LFGTLMIHKSACCNNPSYIDRLISVFMRSLQKMVRE------HLNPQTA 1008

Query: 2320 HRPEADATNQTGRGSADL-SLSVNNLKTLMKLISERVLLLPESKRLFCQMLPTVLGEKGT 2378
                + +T  T  G+++L  LS++ +KT + ++S       E ++ F Q + T L EK  
Sbjct: 1009 ----SGSTEATAAGTSELVMLSLDLVKTRLAVMSM------EMRKNFIQTILTSLIEKSP 1058

Query: 2379 DTGVLLAILELVRDWVEHDFKGSNQVASTAPLVIKDVVAFMQRLAQVDCSGMTPAVLEEW 2438
            D  +L A++++V +WV+++   S   A+  P + +  +  ++ +  ++     P  L E 
Sbjct: 1059 DAKILRAVVKIVEEWVKNN---SPMAANQTPTLREKSILLVKMMTYIE--KRFPEDL-EL 1112

Query: 2439 DRMYLKLLHRLCSDTTKYNLSVRQEVFQKVERQFMLGLRSRDPEMRQKFFTLYHDSISKT 2498
            +  +L L++ +  D          E+  K+E  F+ GLR   P +R KFF ++ +S+ + 
Sbjct: 1113 NAQFLDLVNYVYRDEALSG----SELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRR 1168

Query: 2499 LFTRLQYIIQTQEWEALSDVFWLKQCLDLLLAILVEHEPITLAPNSAQVPPL-------- 2550
            ++ RL Y+  +Q WEA+   FW+KQC++LLLA+  +   I  +   A +P +        
Sbjct: 1169 VYERLLYVTCSQNWEAMGSHFWIKQCIELLLAVCEKSTAIGTSCQGAMLPSITNVINLAD 1228

Query: 2551 --------MASGVVP---ERAGMQLQACD--------PPD-----------ESDGATPTF 2580
                    M + V     ER   + +  D        P D           E D      
Sbjct: 1229 SHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLH 1288

Query: 2581 MGIVNKHARFLNEVSKLQVADLVMPLRELAHTDAHVAYHMWVLVFPIVWATLQKEEQVML 2640
            M + N+H +FL+ + +++   L+    +L H    +A   WV +FP +W  L   +Q  L
Sbjct: 1289 M-LTNRHDKFLDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHAL 1347

Query: 2641 AKPMITLLSKEYHSKQLDKRPNVVQALLEGLSLSQPQPKIPSE--LIKFLGKTYNAWHIA 2698
            A  +   L    H  Q D +P+ +   +E  ++SQ  P IP    ++K+LGKT+N W  +
Sbjct: 1348 AGEISPFLCSGSHQVQRDCQPSALNCFVE--AMSQCVPPIPMRPCVLKYLGKTHNLWFRS 1405

Query: 2699 ISLLESHVM---------------------LFPQETRCFDALAELYRMLNEEDVRYGLWK 2737
              +LE                         + P +    D+LAELY +L EED+  GLW+
Sbjct: 1406 TLMLEHQAFEKGLSLPIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQ 1465

Query: 2738 RRTITADTRAGLSLLQHGLWQRAQDVFYNAMNKATQGS--YNAGVVSKAEMCLWEEQWVA 2795
            +R   ++T   ++  QHG +++AQ+ +  AM+KA +     NA      E  LWE+ W+ 
Sbjct: 1466 KRCKFSETATAIAYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIR 1525

Query: 2796 CAKRLSQWDILVDFGRSVENYD--ILLDTLIKVPDWTLLKETVLPKAQVDESP------K 2847
            C+K L+QW+ L +FG+S  + +  ++L+   +V +WT +KE ++   QV+ S       K
Sbjct: 1526 CSKELNQWEALTEFGQSKGHINPYLVLECAWRVSNWTAMKEALV---QVEVSCPKEMAWK 1582

Query: 2848 FRMVQAYVALNDGSLASVTEADGRVGQGVELALHQWWQLPEMAVQSHIPXXXXXXXXXXX 2907
              M + Y+A+       ++  +  V     LA+ +W +LP +    H P           
Sbjct: 1583 VNMYRGYLAICHPEEQQLSFIERLVEMASSLAIREWRRLPHVVSHVHTP----------L 1632

Query: 2908 XXSARVLLEIGNGNKPQPQGSGQV-AGIQ----GPAGAYVDLKDILETWRLRTPNEWDEL 2962
              +A+ ++E+        Q + Q+ AG+Q    G   +  D+K +++TWR R P   D+L
Sbjct: 1633 LQAAQQIIEL--------QEAAQINAGLQPTNLGRNNSLHDMKTVVKTWRNRLPIVSDDL 1684

Query: 2963 TVWMDLLQWRNHMYNTVINAFKGFSETNPQLHQ--LGFRDKAWSVNKLAYVARRQGLYEV 3020
            + W  +  WR H Y  ++ A++  S  +P  +   LG    A ++ +   +AR+QGL  V
Sbjct: 1685 SHWSSVFMWRQHHYQAIVTAYENSSHHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNV 1744

Query: 3021 CVSVLNKMYGFLTMEVQEAFVKIREQAKAYLEMKG-----ELASGLSLINTTNLEYFPLQ 3075
             + +L++++   T+ + + F KIR+Q K YL++ G     E   GL +I +TNL+YF  +
Sbjct: 1745 ALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKE 1804

Query: 3076 HKAEIFRLKGDFLQKMNDMENANQAYCTAISLYKHLPKGWISWGNHCDQVY-KETNEDLW 3134
              AE + LKG FL ++N  E AN+A+  A+ ++  L K W  WG++ + ++ KE    L 
Sbjct: 1805 MTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLESIFVKERQLHLG 1864

Query: 3135 LEYAVSCFLQGIKYGSK-HGRNHLARVLFLLSFDNQTGSVSKAFDKYCDSIPQWVWLAWI 3193
            +  A++C+L   ++ ++   R +LA+VL+LLSFD+   +++ A DKYC  +P   WLAWI
Sbjct: 1865 VS-AITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWI 1923

Query: 3194 PQLLLSLQRPEAASCKNVILKLAAVFPQALYYWLRTYLL 3232
            PQLL  L   E     N+I ++  V+PQA+Y+ +RT  L
Sbjct: 1924 PQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYL 1962



 Score =  210 bits (534), Expect = 2e-52,   Method: Compositional matrix adjust.
 Identities = 149/470 (31%), Positives = 228/470 (48%), Gaps = 40/470 (8%)

Query: 3459 KREFERDLDPDSASTFPATLAELTEKLKTWKGVLQSNVEDRLPAVLKXXXXXXXXXXF-- 3516
            K +F  D D     +    L  L  KLK W  +L++  + +LP              F  
Sbjct: 2123 KGQFTTDFDFSVPGSM--KLHNLISKLKKWIKILEAKTK-QLPKFFLIEEKCRFLSNFSA 2179

Query: 3517 HVLDIEVPGQYFNDQEVAPDHT-VKLDRIGADVPIVRRHGSSHRRLTLVGNDGSQKHFLV 3575
               ++E+PG++   +   P H  +K+ R    V IV++H ++ RRL + G++G    +LV
Sbjct: 2180 QTAEVEIPGEFLMPK---PTHYYIKIARFMPRVEIVQKHNTAARRLHIRGHNGKIYPYLV 2236

Query: 3576 QT-SLTPSARSDERMVQLFRVLNRLLDKHKESRRRHLAFNTPIIIPVWPQVRLVEDDLMY 3634
               +    +R +ER++QL R+LN  L+K KE+ +RHL F  P ++ V PQ+RLVED+   
Sbjct: 2237 MNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSS 2296

Query: 3635 STFGEVYEINCARYGREADLPITHFKERLN--QAITGQLNLEALVDLRLHTYNEITNRFV 3692
             +  E+Y+  CA+ G E D PI+ + +RL   QA   Q + + L D+      E+ +  V
Sbjct: 2297 LSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASHQVLRDI----LKEVQSNMV 2352

Query: 3693 SENVFSQFMYKTLPTCNHLWTFKKQFAVQLALSGFMSYMLQIGGRSPNKILFAKNTGKV- 3751
              ++  ++   T P     WTF+K F +QLAL GF  ++L +   +P  +  A++TGK+ 
Sbjct: 2353 PRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLN 2412

Query: 3752 ---FQNDFHPAYDIHGMVEFAEPVPFRLTRNLQTFFTPFGVEGLFISSMCAAAQAVVAPK 3808
               F+ D +   D  G ++   PVPFRLT N+  F T  GV G   +SM A A+    P 
Sbjct: 2413 VAYFRFDIN---DATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQP- 2468

Query: 3809 NQHVKHQLAMFFRDELIXXXXXXXXXXXXANGTAG---GMSSAELKTKVAENVEQVITRV 3865
            N  V   L    RDE+I                AG    M S +L + V + V  ++TR+
Sbjct: 2469 NFKVDGVLKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRL 2528

Query: 3866 QKIAPQCFPEEEENSTEPPQSVQRGVSDLVDAALRPKSLCMMDPTWHPWF 3915
              +A   F   E             V+ LV AA    +LC MDP WHPW 
Sbjct: 2529 HNLAQ--FDGGESK-----------VNTLVAAANSLDNLCRMDPAWHPWL 2565

 Score =  567 bits (1462), Expect = e-161,   Method: Compositional matrix adjust.
 Identities = 404/1460 (27%), Positives = 706/1460 (48%), Gaps = 183/1460 (12%)

Query: 1825 PSDLVHHRKELIKFGWNHLKREESASKQWAFVNVCQFLEAYQAPEKIILQVFVALLRTCQ 1884
            P  +   +K++IKF WN +K E++  KQ A++    F+  +  P K++ QVFVALLR+  
Sbjct: 1876 PEIIAEIKKDIIKFCWNFIKLEDTLIKQSAYLVTSYFISKFDFPIKVVTQVFVALLRSSH 1935

Query: 1885 PEHRVLVKQALDILMPALPRRLPLGENKIPIWIRYTKKILVEEGHSVPNLIHIFQLLVRH 1944
             E R LVKQ+LD+L P L  R+         WI + K+++VE   S  N++  +Q L+ H
Sbjct: 1936 VEARYLVKQSLDVLTPVLHERMN-AAGTPDTWINWVKRVMVENSSSQNNIL--YQFLISH 1992

Query: 1945 ANLFYNCRAQFVPQMVNSLSRLGLPQNTPLENRRLAIDLAGLVVMWEKR--RQAEAKGSS 2002
             +LF+N R  F+  +++ ++++    N+  ++  LAIDLA L++ WE +         + 
Sbjct: 1993 PDLFFNSRDLFISNIIHHMNKITFMSNSNSDSHTLAIDLASLILYWENKTLEITNVNNTK 2052

Query: 2003 TEGDGQSKSAGAEGQV-PAEAIAAGGAPSGTKRTAEAAGLTGVGDEASKRTKSESGLPGL 2061
            T+ DG    + ++  + P E                 A  T +  +A             
Sbjct: 2053 TDSDGDVVMSDSKSDINPVE-----------------ADTTAIIVDA------------- 2082

Query: 2062 AGMSPNLPTGPTNSIPNIGTPGSMGQADEEFKPNAAMEEMIINFLIRVALVTEPKDKETQ 2121
                            N  +P S+            + E    FLIR    +  +  ET+
Sbjct: 2083 ----------------NNNSPISLH-----------LREACTAFLIRYVCASNHRAIETE 2115

Query: 2122 AMYKQALELLTQAL--EVWPHANVKFNYLEKILSAQQPAGQSKDPATALAQGLDVMNKAV 2179
             +  +A+ +L++ +  + W + NVK  Y EK L  Q     S++        LDV+    
Sbjct: 2116 -LGLRAINILSELISDKHWTNVNVKLVYFEKFLIFQD--LDSENILYYCMNALDVLYVFF 2172

Query: 2180 EKQPHLFIRNNVHHIIQVLEPSFNCKLPEIGNSLCTLLKMVFEAFPVDASDTHQDVKLLH 2239
            + +   +I  N+  I  +LE        ++  +L  +L+++ +A                
Sbjct: 2173 KNKTKEWIMENLPTIQNLLEKCIKSDHHDVQEALQKVLQVIMKAIKA------------- 2219

Query: 2240 QKVEELIQKQ------LTTVTSNPTQPPVEASVINVMISFTLNVLKTLVAGNKQYVDKFM 2293
            Q V  +I+++      +  +TS  TQ   E S +   ++        L       +   +
Sbjct: 2220 QGVSVIIEEESPGKTFIQMLTSVITQDLQETSSVTAGVTLAW----VLFMNFPDNIVPLL 2275

Query: 2294 LYLVRVFHRLAREMATTSAQLARQQGHRPEADATNQTGRGSADLSLSVNNLKTLMKLISE 2353
              L++ F +L ++  + S         +P+     +  R +  L      L+ ++ ++S 
Sbjct: 2276 TPLMKTFSKLCKDHLSIS---------QPKDAMALEEARITTKL------LEKVLYILSL 2320

Query: 2354 RVLLLPESKRLFCQMLPTVLGEKGTDTGVLLAILELVRDWVEHDFKGSNQVASTAPLVIK 2413
            +V LL +S+R F   +  +L +   D   L  I+ + R W+      + ++  T    +K
Sbjct: 2321 KVSLLGDSRRPFLSTV-ALLIDHSMDQNFLRKIVNMSRSWI-----FNTEIFPT----VK 2370

Query: 2414 DVVAFMQRLAQVDCSGMTPAVLEEWDRMYLKLLHRLCSDTTKYNLSVRQEVFQKVERQFM 2473
            +  A + ++   +  G  P++ + +  + LKL      D   +N     E+  ++E+ F+
Sbjct: 2371 EKAAILTKMLAFEIRG-EPSLSKLFYEIVLKLF-----DQEHFN---NTEITVRMEQPFL 2421

Query: 2474 LGLRSRDPEMRQKFFTLYHDSISKTLFTRLQYIIQTQEWEALSDVFWLKQCLDLLLAILV 2533
            +G R  D  +R++F T+  +S+ + +  RL Y+I+ Q WE ++D  WL Q L LL     
Sbjct: 2422 VGTRVEDIGIRKRFMTILDNSLERDIKERLYYVIRDQNWEFIADYPWLNQALQLLYGSFN 2481

Query: 2534 EHEPITLAPNSAQVPPLMASGVVPERAGMQLQACDPPDESDGATPTFMGIVNKHARFLNE 2593
              + ++L       PP +    +PE A M  +  D               V  H   +  
Sbjct: 2482 REKELSLKNIYCLSPPSILQEYLPENAEMVTEVND---------LELSNFVKGHIASMQG 2532

Query: 2594 VSKLQVADLVMPLRELAHTDAHVAYHMWVLVFPIVWATLQKEEQVMLAKPMITLLSKEYH 2653
            + ++  +D +  L E+ + D    +  WV +FP V+ ++ K E+    + +ITLLSK YH
Sbjct: 2533 LCRIISSDFIDSLIEIFYQDPKAIHRAWVTLFPQVYKSIPKNEKYGFVRSIITLLSKPYH 2592

Query: 2654 SKQLDKRPNVVQALLEGLSLSQPQPKIPSELIKFLGKTYNAWHIAISLLES-HVMLFPQE 2712
            ++Q+  R NV+  LL+ +S  +   ++P  L+K+L  +YNAW+ +I++LES         
Sbjct: 2593 TRQISSRTNVINMLLDSISKIE-SLELPPHLVKYLAISYNAWYQSINILESIQSNTSIDN 2651

Query: 2713 TRCF----DALAELYRMLNEEDVRYGLWKRRTITADTRAGLSLLQHGLWQRAQDVFYNAM 2768
            T+      DAL ELY  L EED+ YGLW+RR    +T  GLS  Q GLW +AQ ++  A 
Sbjct: 2652 TKIIEANEDALLELYVNLQEEDMFYGLWRRRAKYTETNIGLSYEQIGLWDKAQQLYEVAQ 2711

Query: 2769 NKATQGSYNAGVVSKAEMCLWEEQWVACAKRLSQWDILVDFGRSVENYDILLDTLIKVPD 2828
             KA  G   A   S++E  LWE+ W+ CA++L  WD+L +  +     D+LL+   +V D
Sbjct: 2712 VKARSG---ALPYSQSEYALWEDNWIQCAEKLQHWDVLTELAKHEGFTDLLLECGWRVAD 2768

Query: 2829 WT----LLKETVLPKAQVD-ESPKFRMVQAYVALNDGSLASVTEADGR--VGQGVELALH 2881
            W      L+++V  K+ +D  +P+ +M + ++AL + + +   + + R    +G++L+L 
Sbjct: 2769 WNSDRDALEQSV--KSVMDVPTPRRQMFKTFLALQNFAESRKGDQEVRKLCDEGIQLSLI 2826

Query: 2882 QWWQLPEMAVQSHIPXXXXXXXXXXXXXSARVLLEIGNGNKPQPQGSGQVAGIQGPAGAY 2941
            +W  LP     +H               + ++              +     +Q      
Sbjct: 2827 KWVSLPIRYTPAHKWLLHGFQQYMEFLEATQIY------------ANLHTTTVQNLDSKA 2874

Query: 2942 VDLKDILETWRLRTPNEWDELTVWMDLLQWRNHMYNTVINAF--------KGFSETNPQL 2993
             ++K IL+ WR R PN WD++ +W DL+ WR H +  + NA+        +  S +N   
Sbjct: 2875 QEIKRILQAWRDRLPNTWDDVNMWNDLVTWRQHAFQVINNAYLPLIPALQQSNSNSNINT 2934

Query: 2994 HQL-GFRDKAWSVNKLAYVARRQGLYEVCVSVLNKMYGFLTMEVQEAFVKIREQAKAYLE 3052
            H   G+ + AW +N+ A+VAR+  + +VC+S L ++Y    +E+QEAF+K+REQAK + +
Sbjct: 2935 HAYRGYHEIAWVINRFAHVARKHNMPDVCISQLARIYTLPNIEIQEAFLKLREQAKCHYQ 2994

Query: 3053 MKGELASGLSLINTTNLEYFPLQHKAEIFRLKGDFLQKMNDMENANQAYCTAISLYKHLP 3112
               EL +GL +I+ TNL YF    KAE F LKG FL K+   E ANQA+ TA+ +  +L 
Sbjct: 2995 NMNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAYEEANQAFATAVQIDLNLA 3054

Query: 3113 KGWISWGNHCD-QVYKETNEDLWLEYAVSCFLQGIK-YGSKHGRNHLARVLFLLSFDNQT 3170
            K W  WG   D ++ +E N   +   A+SC+LQ    Y +   R  L R+L+L+S D+ +
Sbjct: 3055 KAWAQWGFFNDRRLSEEPNNISFASNAISCYLQAAGLYKNSKIRELLCRILWLISIDDAS 3114

Query: 3171 GSVSKAFDKYCDSIPQWVWLAWIPQLLLSLQRPEAASCKNVILKLAAVFPQALYYWLRTY 3230
            G ++ AFD +   IP W W+ +IPQLL SL   EA   +++++++A  +PQAL++ LRT 
Sbjct: 3115 GMLTNAFDSFRGEIPVWYWITFIPQLLTSLSHKEANMVRHILIRIAKSYPQALHFQLRTT 3174

Query: 3231 -----LLERRDIA---NKPD 3242
                 +++R+ +A   +KPD
Sbjct: 3175 KEDFAVIQRQTMAVMGDKPD 3194



 Score =  521 bits (1342), Expect = e-147,   Method: Compositional matrix adjust.
 Identities = 456/1724 (26%), Positives = 778/1724 (45%), Gaps = 239/1724 (13%)

Query: 8    EQHARRFLEQDLSMQNRLTLATEVRDSIEIVHTSE-YLNFLKSYFVVFSNLLTKITKPQA 66
            EQ A RF + D ++Q+R +  +E+ D +E++++ E Y  FL++   +  N L ++     
Sbjct: 8    EQFASRFRDDDATLQSRYSTLSELYDIMELLNSPEDYHFFLQAVIPLLLNQLKEVPISYD 67

Query: 67   TDNVEHKLRNVVIEILNRLPHSEVLRLFVQDLLKLSMHVLACDNEENGLICLRIIFDLHK 126
              + E KLRN +++I NR   ++  + +  ++L+  + VL  +NEENG++C++++  L K
Sbjct: 68   AHSPEQKLRNSMLDIFNRCLMNQTFQPYAMEVLEFLLSVLPKENEENGILCMKVLTTLFK 127

Query: 127  NFRPALEPDVQQFLDFVREIYQNFRATVT-YFFEESSAPDVQLAA-----AHHNLGYMGQ 180
            +F+  L+  +  F+  + +IY+N    +   F+E   A    L +     A   L    +
Sbjct: 128  SFKSILQDKLDSFIRIIIQIYKNTPNLINQTFYEAGKAEQGDLDSPKEPQADELLDEFSK 187

Query: 181  MRSPAGGPM--------------SGQLNQSTRSFKVVTECPLIVMFLFQLYPRYVPTNIP 226
                   P               S  L  S  SFK+++ECP+ ++ L+  Y +   T++P
Sbjct: 188  NDEEKDFPSKQSSTEPRFENSTSSNGLRSSMFSFKILSECPITMVTLYSSYKQLTSTSLP 247

Query: 227  LLLPLMVSAIGIPGPTEVPPTLKNVYAELKGAQ-VKIDASIAG--MFIGIFLCWLQTVSF 283
               PL+++ + I    +     +   AE +G     I   I     +    L  ++  SF
Sbjct: 248  EFTPLIMNLLNIQIKQQQEAREQ---AESRGEHFTSISTEIINRPAYCDFILAQIKATSF 304

Query: 284  LTYL-LRSFA-DCIRPHEDXXXXXXXXXXXXCPDSVS-IRKELLVATRHVLATDFRRGFF 340
            L Y+ +R +A + ++ + +            CP  +S  RKELL ATRH+L+T++++ F 
Sbjct: 305  LAYVFIRGYAPEFLQDYVNFVPDLIIRLLQDCPSELSSARKELLHATRHILSTNYKKLFL 364

Query: 341  PQIDTLLDERVLVGTGRACYETLRPLAYSLLAELIHHVRLDLSLPQLSRIVYLFSRNVHD 400
            P++D L DER+L+G G   +ETLRPLAYS +A+ IH++R +L L ++ + + +++  + D
Sbjct: 365  PKLDYLFDERILIGNGFTMHETLRPLAYSTVADFIHNIRSELQLSEIEKTIKIYTGYLLD 424

Query: 401  SSLPLSVQTTCVRLMLNLVETIFGRRVDHLSREE------GRALLGRILDAFVSKFGTLK 454
             SL L+VQ    +L+LNLVE     R+  L +E        + LL  I+D+++++F TL 
Sbjct: 425  ESLALTVQIMSAKLLLNLVE-----RILKLGKENPQEAPRAKKLLMIIIDSYMNRFKTLN 479

Query: 455  HSIPQLLEEDG-------------------EDRKERRTLRSRLE---------LPVQAAL 486
                 +++  G                    D++    +R  LE          P +  +
Sbjct: 480  RQYDTIMKYYGRYETHKKEKAEKLKNSIQDNDKESEEFMRKVLEPSDDDHLMPQPKKEDI 539

Query: 487  N-----------------------------LQVPPEHSKEVMDCKQLLKTLIMGMKTLVW 517
            N                             L +P   +  + D   L +TL+  +KT++ 
Sbjct: 540  NDSPDVEMTESDKVVKNDVEMFDIKNYAPILLLPTPTNDPIKDAFYLYRTLMSFLKTIIH 599

Query: 518  SITHFNATPLPQMNNAPVP------VKGMREEEVRLASGILKSGLHCLALFKEKDEE--- 568
             +  FN  P P       P       +    EEV +   +    +  L  FK+ +E+   
Sbjct: 600  DLKVFN--PPPNEYTVANPKLWASVSRVFSYEEVIVFKDLFHECIIGLKFFKDHNEKLSP 657

Query: 569  ----------------------KEMYTHYSSVFAVMEHRNLMDMFSLCMPQLFDCMLANL 606
                                  +E+  + + +F  M++    ++    +P +++ ML + 
Sbjct: 658  ETTKKHFDISMPSLPVSATKDARELMDYLAFMFMQMDNATFNEIIEQELPFVYERMLEDS 717

Query: 607  QLLQIFSTLLYTPKVTKHFADVLVNYLVTSKLDTLKQPDTPAAKLVLQLFRYLFVAVAKF 666
             LL +  + L +   + +FA +L+ +L   KL  L   D   + ++++LF+  F++V  F
Sbjct: 718  GLLHVAQSFLTSEITSPNFAGILLRFL-KGKLKDLGNVDFNTSNVLIRLFKLSFMSVNLF 776

Query: 667  SADCERVLQPHVITLMESCMKNATEVEKPLGYMQLLRTMFRALSGGKFELLFREFIPTLQ 726
                E VL PH+  L+ + +K +T  E+PL Y  L+RT+FR++ GG+FE L+R   P LQ
Sbjct: 777  PNINEVVLLPHLNDLILNSLKYSTTAEEPLVYFYLIRTLFRSIGGGRFENLYRSIKPILQ 836

Query: 727  PCLNMLLAMVEGPTGLDMIDLVVELCLTXXXXXXXXXXXXXXXMKPLVLALGGSDELVAL 786
              L  L  M+         +L VELC+T               MKPLV AL    +LV+ 
Sbjct: 837  VLLQSLNQMILTARLPHERELYVELCITVPVRLSVLAPYLPFLMKPLVFALQQYPDLVSQ 896

Query: 787  GLRTLEFWIDSLNPEFLEPSMATVMSDLILTLWSHLRPKPYXXXXXXXXXXXXXXX--RN 844
            GLRTLE  ID+L  E+ +P +  V+ D+   L++ L+P+P+                 RN
Sbjct: 897  GLRTLELCIDNLTAEYFDPIIEPVIDDVSKALFNLLQPQPFNHAISHNVVRILGKLGGRN 956

Query: 845  RRFLKEPLSLECKENPEHGLRLILTFE----PTTSFLVPLDRCIYLARAAVMGTQVGVDS 900
            R+FLK P  L   E  E  +  I  F+    P     VPL     +  A  +      D 
Sbjct: 957  RQFLKPPTDL--TEKTELDIDAIADFKINGMPED---VPLSVTPGIQSALNILQSYKSDI 1011

Query: 901  FYRKHALKFLRVCLASVLNLKGNVGGEGVTPGQLSTMFITSVDPSRRRAENPNVKGDLGV 960
             YRK A K+L  C   VL L      E   P   + +  T+V+  +   E   ++ +  +
Sbjct: 1012 HYRKSAYKYL-TC---VLLLMTKSSAEF--PTNYTELLKTAVNSIK--LERIGIEKNFDL 1063

Query: 961  K---TKTQLMAERSVFKVLLMTVIAASMELELQDGKDDFAANICRHFAMIFHVESAANNP 1017
            +    K     + ++F  LL +V  A+   EL+D   D   N+  HF ++  V +   N 
Sbjct: 1064 EPTVNKRDYSNQENLFLRLLESVFYATSIKELKDDAMDLLNNLLDHFCLL-QVNTTLLNK 1122

Query: 1018 GGNSGPHTVTASGVPNARTRSNRAQANLKELDPLIFLDAL-------------VAVLADE 1064
               +G   +     PN              LD  + LDA+             V VLA +
Sbjct: 1123 RNYNGTFNIDLKN-PNFM------------LDSSLILDAIPFALSYYIPEVREVGVLAYK 1169

Query: 1065 NRAHAKAALNGLNIFAETLLLLARSKHTGILTPRGVSTPGTXXXXXXXXXXXXXXXXXGV 1124
             R + K+ L    I+ E L L     H+ I                              
Sbjct: 1170 -RIYEKSCL----IYGEELAL----SHSFI------------------------------ 1190

Query: 1125 RVPVFEQLLPRLLHCCYGSTWQAQMGGVIGLGALVG--KATVEMLCQFQVRAVRALIYVL 1182
                  +L  + +H CY  T+  + GGV+G+  L+   K++   L ++Q      L++VL
Sbjct: 1191 -----PELAKQFIHLCYDETYYNKRGGVLGIKVLIDNVKSSSVFLKKYQYNLANGLLFVL 1245

Query: 1183 KRLPPHANAEQEEASXXXXXXXXXXXXXXXXXSEPRRQSFLGVVEVLAGELFNSNASYIV 1242
            K     A +   +++                  +   +     +  +  EL N+N    V
Sbjct: 1246 KDTQSEAPSAITDSAEKLLIDLLSITFADVKEEDLGNKVLENTLTDIVCELSNANPK--V 1303

Query: 1243 RKNVQSCLALLASRTGSEVSELLEPHYQPLLTPLVYKPLRSKHAEQQVGTVMALNFCLAL 1302
            R   Q  L  +++ TG  + +L++   Q LL+P+  KPLR+     Q+G V A+ FCL+L
Sbjct: 1304 RNACQKSLHTISNLTGIPIVKLMDHSKQFLLSPIFAKPLRALPFTMQIGNVDAITFCLSL 1363

Query: 1303 RPPLLKMRQELSNILQESLQIAEADESVLNGKFMNPKMAAT---LTKLRTVCIELLCTAM 1359
                L   +EL  +LQES+ +A+A++  L+         +T   L +LR  CI+LL  A+
Sbjct: 1364 PNTFLTFNEELFRLLQESIVLADAEDESLSTNIQKTTEYSTSEQLVQLRIACIKLLAIAL 1423

Query: 1360 AWADFKTQSHAELRSRIIAMFFKSLTCRTPEIVAVAKEGLR-QVIQQQKMPKELLQSSLR 1418
               +F T     +R RI+A+FFK++   +PEI+    E L+  + +  K+PKELLQ+ L+
Sbjct: 1424 KNEEFATAQQGNIRIRILAVFFKTMLKTSPEIINTTYEALKGSLAENSKLPKELLQNGLK 1483

Query: 1419 PILVNLAHYKNLTMPXXXXXXXXXXXXSNWFNVTLGEKLMEHLKKWLEPEKLSSSQKSWK 1478
            P+L+NL+ ++ LT+P              +F V +G KL++HL  W   E L +      
Sbjct: 1484 PLLMNLSDHQKLTVPGLDALSKLLELLIAYFKVEIGRKLLDHLTAWCRVEVLDTLFGQDL 1543

Query: 1479 AGEEP-KIAGAIIELFHLLPPAAQKFLDQLVTLTMQLEAALPPSQVYSELNSPYRLPLTK 1537
            A + P KI  +II +FHLLPP A  FL+ L+   M LE  L       +L+SP+R PL +
Sbjct: 1544 AEQMPTKIIVSIINIFHLLPPQADMFLNDLLLKVMLLERKL-----RLQLDSPFRTPLAR 1598

Query: 1538 FLNRYAPEAVDYFLGRLTQPTVFRRFMDIIQSEGGQPLREELAR 1581
            +LNR+     +YF   +T   +     +I+Q    + L E+  +
Sbjct: 1599 YLNRFHNPVTEYFKKNMTLRQLVLFMCNIVQRPEAKELAEDFEK 1642



 Score =  219 bits (557), Expect = 5e-55,   Method: Compositional matrix adjust.
 Identities = 167/587 (28%), Positives = 264/587 (44%), Gaps = 83/587 (14%)

Query: 3365 FEAAKDIMEALRTKHTNLANELEVMLTEIGARFVPLPEERLLAVVHALL----------- 3413
            +E  +++   L+T +  LA  LE ++ +I  RF    +E L  +++ LL           
Sbjct: 3205 WEYLQELNNILKTAYPLLALSLESLVAQINDRFKSTTDEDLFRLINVLLIDGTLNYNRLP 3264

Query: 3414 --HRCYKYPTATTAEVPQSLKKELAGVCRACFSVDTINKHVDFVTEYKREFERDLDPDSA 3471
               +  K P  T   + +     LA   R  F+ D I+   D+ T  KR           
Sbjct: 3265 FPRKNPKLPENTEKNLVKFSTTLLAPYIRPKFNADFIDNKPDYETYIKR----------- 3313

Query: 3472 STFPATLAELTEKLKTWKGVLQSNVEDRLPAVLKXXXXXXXXXXFH---VLDIEVPGQYF 3528
                         L+ W+  L++ + DR                FH     DIE+PGQY 
Sbjct: 3314 -------------LRYWRRRLENKL-DRASKKENLEVLCPHLSNFHHQKFEDIEIPGQYL 3359

Query: 3529 --NDQEVAPDHTVKLDRIGADVPIVRRHGSSHRRLTLVGNDGSQKHFLVQTSLTPSARSD 3586
               D  V   H +K+ R    V  VR   SS+RRL + G+DGS   F VQ      +R +
Sbjct: 3360 LNKDNNV---HFIKIARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVRHSRRE 3416

Query: 3587 ERMVQLFRVLNRLLDKHKESRRRHLAFNTPIIIPVWPQVRLVEDDLMYSTFGEVYEINCA 3646
            ERM QL+R+ N+ L K+ E+RRR + FN PI IP+ PQVR++ D + ++T  E++   C 
Sbjct: 3417 ERMFQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCK 3476

Query: 3647 RYGREADLPITHFKERLNQAITGQLNLEALVDLRLHTYNEITNRFVSENVFSQFMYKTLP 3706
            + G + D       ++LN A    L    +  L++  +N I   FV  NV          
Sbjct: 3477 KKGFDPDDIQDFMADKLNAAHDDALPAPDMTILKVEIFNSIQTMFVPSNVLKDHFTSLFT 3536

Query: 3707 TCNHLWTFKKQFAVQLALSGFMSYMLQIGGRSPNKILFAKNTGKVFQNDFHPA------- 3759
                 W F+KQFA Q +   FMSYM+ I  R+P+KI   K +G VF  +  P+       
Sbjct: 3537 QFEDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSRFPYERV 3596

Query: 3760 ------YDI-----HGMVEFAEPVPFRLTRNLQTFFTPFGVEGLFISSMCAAAQAVVAPK 3808
                  +D+       +    EPVPFRLT N+Q+      +EG+F  ++   ++A++ P 
Sbjct: 3597 KPLLKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPD 3656

Query: 3809 NQHVKHQLAMFFRDELIXXXXXXXXXXXXANGTAGGMSSAELKTKVAENVEQVITRVQKI 3868
            N+ +   LA+F RDE+I            +N     + + +L+  V  NV+ +I +V ++
Sbjct: 3657 NE-LNTYLALFIRDEII---------SWFSNLHRPIIENPQLREMVQTNVDLIIRKVAQL 3706

Query: 3869 APQCFPEEEENSTEPPQSVQRGVSDLVDAALRPKSLCMMDPTWHPWF 3915
                      NST  P    + + D + +A+ P++L   D  + PWF
Sbjct: 3707 G-------HLNST--PTVTTQFILDCIGSAVSPRNLARTDVNFMPWF 3744

 Score =  521 bits (1341), Expect = e-146,   Method: Compositional matrix adjust.
 Identities = 465/1779 (26%), Positives = 785/1779 (44%), Gaps = 216/1779 (12%)

Query: 313  CP-DSVSIRKELLVATRHVLATDFRRGFFPQIDTLLDERVLVGTGRACYETLRPLAYSLL 371
            CP ++  +RKELL+A RH+ ATD R+ F P I+ L DE +L+G G    +++RPLAYS L
Sbjct: 376  CPKEAAHLRKELLIAARHIFATDLRQKFIPSIEQLFDEDLLIGKG-VTLDSIRPLAYSTL 434

Query: 372  AELIHHVRLDLSLPQLSRIVYLFSRNVHDSSLPLSVQTTCVRLMLNLVETIFGRRVDHLS 431
            A+L HHVR  L++  L + V LFS+NVHD SL + +QT   +L+LNLV+ +  R      
Sbjct: 435  ADLAHHVRQSLNIDVLIKAVNLFSKNVHDESLAVGIQTMSCKLLLNLVDCL--RHHSETE 492

Query: 432  REEGRALLGRILDAFVSKFGTL-KHSIPQLLEE-DGED------RKERRTLRSRLELP-- 481
             +  +ALL ++L  FV KF T+ K  +P ++++  G                S +  P  
Sbjct: 493  PQRSKALLSKLLKVFVKKFETIAKIQLPLIIQKCKGHAFSGALVNSSGNASLSHINAPDL 552

Query: 482  VQAALNLQVPPE-----HSKEVMDCKQLLKTLIMGMKTLVWSI--THFNATPLPQMNNAP 534
                 N+QV        +S  V + + L+KTL+ G+KT+ W    + F  T     N+  
Sbjct: 553  KDDISNIQVSASGSQWIYSVNVAEFRSLVKTLVGGVKTITWGFFNSKFQLTDTKLANHEK 612

Query: 535  VPVKGMREEEVRLASGILKS-GLHCL----------ALFKEKDEEKEMYTHYSSVFAVME 583
            +    +    + L    +++  ++ +           L     EEKE+  H+S +F +M 
Sbjct: 613  IFGPEIVCSYIDLVYYAMEALDIYTINVNPNQQRTSGLISRSKEEKEVLEHFSGIFLMMH 672

Query: 584  HRNLMDMFSLCMPQLFDCMLANLQLLQIFSTLLYTPKVTKHFADVLVNYLVTSKLDTLKQ 643
             +N  ++FS  +  L + +  N  L  I ++ L  P  +  FA VLV YL+ +K++ +  
Sbjct: 673  SQNFQEIFSTTINFLVERIYKNQSLQVIANSFLANPTTSPLFATVLVEYLL-NKMEEMGS 731

Query: 644  PDTPAAKLVLQLFRYLFVAVAKFSADCERVLQPHVITLMESCMKNATEVEKPLGYMQLLR 703
             +   + L L+LF+ +F +V+ F  + E++L+PH+  ++   M+ A   E+P  Y  LLR
Sbjct: 732  -NLERSNLYLRLFKLVFGSVSLFPVENEQMLRPHLHKIVNRSMELALISEEPYNYFLLLR 790

Query: 704  TMFRALSGGKFELLFREFIPTLQPCLNMLLAMVEGPTGLDMIDLVVELCLTXXXXXXXXX 763
             +FR++ GG  +LL++EF+P L   L  L  +  G     M DL VELCLT         
Sbjct: 791  ALFRSIGGGSHDLLYQEFLPLLPNLLEGLNRLQSGFHKQHMRDLFVELCLTVPVRLSSLL 850

Query: 764  XXXXXXMKPLVLALGGSDELVALGLRTLEFWIDSLNPEFLEPSMATVMSDLILTLWSHLR 823
                  M PLV AL GS  L++ GLRTLE  +D+L P+FL   +  V + L+  LW  LR
Sbjct: 851  PYLPMLMDPLVSALNGSPTLISQGLRTLELCVDNLQPDFLYDHIQPVRAALMQALWKTLR 910

Query: 824  PKPYXXXXXXXXXXXXXXXRNRRFLKEPLSLECKENPEHGLRLILTF-EPTTSFLVPLDR 882
             +                  NR+ + EP +L    N +  + ++  F E  T    P+D 
Sbjct: 911  NQD-NAALVAFRVLGKFGGGNRKMMVEPQALSYIINDKPTISIVTYFQEYETPIDFPVDE 969

Query: 883  CIYLARAAVMGTQVGVDSFYRKHALKFLRVCLASVLNLKGNVGGEGVTPGQLSTMFITSV 942
             I  A  A +G+    D FYR+ + + +R  LA+ ++L             +     T V
Sbjct: 970  AIKSAFRA-LGSN-STDQFYRRQSWEVIRCFLAAFISLDDE--------KHMLLKLFTHV 1019

Query: 943  DPSRRRAEN-PNVKGDLGVKTKTQLMAERSVFKVLLMTVIAASMELELQDGKDDFAANIC 1001
            D    +  N    +   G +T       R   +  L+ ++ AS   +L+D      A + 
Sbjct: 1020 DFVENKIMNWSTFQHKAGNETV------RETHQTALIGMLVASATKDLRDSVCPVMAAVV 1073

Query: 1002 RHFAMIFHVESAANNP-GGNSGPHTVTASGVPNARTRSNRAQANLKELDPLIFLDALVAV 1060
            RH+ M+   + A   P  G    H +                      DP+I +DAL + 
Sbjct: 1074 RHYTMVAIAQQAGPFPQKGYQATHGI----------------------DPMILIDALASC 1111

Query: 1061 LADENRAHAKAALNGLNIFAETLLLLARSKHTGILTPRGVSTPGTXXXXXXXXXXXXXXX 1120
            +  E +   K  +  + I  +T         T I+  +                      
Sbjct: 1112 MGHEEKELCKPGIACMGIILDTA--------TNIMGNKD--------------------- 1142

Query: 1121 XXGVRVPVFEQLLPRLLHCCYGSTWQAQMGGVIGLGALVGKATVEMLCQFQVRAVRALIY 1180
                ++P+ + L  +++  CY   W +++GG   +  L    ++  L Q     ++A ++
Sbjct: 1143 -RACKLPIIQYLAEKMVSLCYDRPWYSKVGGCQAIQFLCKHMSLRALFQNLFNFLKAFMF 1201

Query: 1181 VLKRLPPHANAEQEEASXXXXXXX-------XXXXXXXXXXSEPRRQSFLGVVEVLAGEL 1233
            VL  L    +    E +                         + + ++   V+  L   +
Sbjct: 1202 VLMDLEGDVSNGAIEITKSYMKSMLEICLTPINECYKNIDLKDLQAKATYEVIHELVRHI 1261

Query: 1234 FNSNASYIVRKNVQSCLALLASRTGSEVSELLEPHYQPL--LTPLVYKPLRSKHAEQQVG 1291
             + N   IVR+     L  + +     VSE+++PH   L  + P     LR + A  Q+G
Sbjct: 1262 TSPNT--IVREESMVLLKHIGTIQSKTVSEVMDPHKDVLADIIPPKKHLLRHQPANAQIG 1319

Query: 1292 TVMALNFCLALRPPLLKMRQELSN-----ILQESLQIAEADESVLNGKFMNPKMAATLTK 1346
             +    FC  L P L  +  +L+N        E L ++EA+++ L  K    K    L  
Sbjct: 1320 LMDGNTFCTTLEPRLFTI--DLTNTYHKLFFHELLTLSEAEDATL-AKLDCYKNVPNLIP 1376

Query: 1347 LRTVCIELLCTAMAWADFKTQSHAELRSRIIAMFFKSLTCRTPEIVAVAKEGLRQVIQQQ 1406
            LRT  +  L      +D         + +II + FK +     E+   A   ++  I   
Sbjct: 1377 LRTSALRALAACHYISDIG------YKEKIINIIFKVMESDKSELQTTAFHCMKHFITGV 1430

Query: 1407 KMPKELLQSSLRPILVNLAHYKNLTMPXXXXXXXXXXXXSNWFNVTLGEKLMEHLKKWLE 1466
             + KE +QS++RP+L+ L  ++NL++P               FN  L E++++H  K +E
Sbjct: 1431 TLEKEKVQSAMRPLLLKLGDHRNLSIPAIKRLSYFTQIFPQMFNEKLSEQILQHCSKIME 1490

Query: 1467 ---PEKLSSSQK-----SWKAGEEPKIAGAIIELFHLLPPAAQKFLDQLVTLTMQLEAAL 1518
                E  S+S       S K GE  +    +IE+F  +  A+ K++++L  L ++ E  L
Sbjct: 1491 IFVSEYKSTSPNVNFFASSKGGEYEQKIVILIEMFFYI-SASVKYIEKLCQLVLKTEKNL 1549

Query: 1519 PPSQVYSELNSPYRLPLTKFLNRYAPEAVDYFLGR--LTQPTVFRRFMDIIQSEGGQPLR 1576
                   E +SPYR  L KFL R+  E VD FL    +  P   R F+ +++ E G   R
Sbjct: 1550 -----MIEASSPYREALIKFLQRFPTETVDLFLTESLMIDPQWNRLFIYLLKHETGVSFR 1604

Query: 1577 EELARSP-NKII-----QSAFPAVEENXXXXXXXXXXXXXXXXXXXXXQATAEAQFQGVA 1630
              +  S  N +I      + FP                              E Q Q V 
Sbjct: 1605 AVIKSSRYNNLIHYLNTHTEFPEA-------------------------LKYEIQHQAVL 1639

Query: 1631 LVSALVKLLPDWLHQNRAVFDALVRLWQSPARQARLINEQGLSLNQVKESKRLV-KCFLN 1689
            ++  L++    W+   + + DAL   WQ+    + L +E  L      +   L+ K  L+
Sbjct: 1640 IIFTLMESDDQWIPTRQDIVDALKNCWQNYL--STLSSEDVLC-----DLWHLIGKILLH 1692

Query: 1690 YLRHDKAEVNVLFEMLSIFLVRTRIDYTFLKEFYMVEVGEGYSPQEKKAVLLCFLELFQT 1749
            Y  ++  ++ +LF++L     R   D  FL++F    V + ++   K+     F+E F  
Sbjct: 1693 YFSNNTNDIELLFQLLRALCFRFIPDVYFLRDFLQHTVAQSFTVNWKRNAFFYFVENFNN 1752

Query: 1750 KRLPQDVLVVAMQMLILPMLTHSFQQNQCWDVVDA----------TIIKTIIEKLLDPPE 1799
              L +++    +  +I+P    SF + +   ++ A           I+   I K+ DP +
Sbjct: 1753 SFLSEELKAKIITAVIIPCFAVSFDKGEGNKLIGAPPTPYQEDEKNIVSVFINKVFDPDK 1812

Query: 1800 EVSADYDESXXXXXXXXX-----XXXXXXXPSDLVHHR-----KELIKFGWNHLKREES- 1848
            +    YD++                       D  + R     + L+ F W  L  + S 
Sbjct: 1813 Q----YDDAVRIALLQLACLLVERASQHIHDGDANNKRQGNKLRRLMTFAWPCLLSKSSV 1868

Query: 1849 --ASKQWAFVNVCQFLEAYQAPEKIILQVFVALLRTCQPEHRVLVKQALDILMPALPRRL 1906
               ++    + +   +      +KI+LQVF +LL+    E R +VKQALD+L PA+P R+
Sbjct: 1869 DPTARYHGHLLLSHIIARLAIHKKIVLQVFHSLLKGHALEARSIVKQALDVLTPAMPLRM 1928

Query: 1907 PLGENKIPIWIRYTKKILVEEGHSVPNLIHIFQLLVRHANLFYNCRAQFVPQMVNSLSRL 1966
              G   +  W   TKKI+VEEGH++  L HI QL++RH  +++  R Q V  ++N + RL
Sbjct: 1929 EDGNTMLTHW---TKKIIVEEGHAMQQLFHILQLIIRHYKVYFPVRHQLVQHLINYMQRL 1985

Query: 1967 GLPQNTPLENRRLAIDLAGLVVMWEKRRQAEAKGSSTEG 2005
            G P    +E+++LA+DLA +++ WE  R  + + + T+G
Sbjct: 1986 GFPPTASIEHKKLAVDLAEVIIKWELHRIKDDRETKTDG 2024



 Score =  406 bits (1043), Expect = e-112,   Method: Compositional matrix adjust.
 Identities = 320/1279 (25%), Positives = 590/1279 (46%), Gaps = 157/1279 (12%)

Query: 2089 DEEFKPNAAMEEMIINFLIR---VALVTEPKD-----KETQAMYKQALELLTQAL--EVW 2138
            D E K +   EE+I    ++   + LV   K      +ET    K  + LL  A+  E+W
Sbjct: 2017 DRETKTDGTEEELIQESSVKRSGIDLVETRKKSFDIIRETTVQGKCVM-LLKMAMRPEIW 2075

Query: 2139 PHA-NVKFNYLEKILSAQQPAGQSKDPATALAQGLDVMNKAVEKQPHLFIRNNVHHIIQV 2197
            P   ++K N+L+K+L+  +    + +    +  G+D +         +   + +  II+ 
Sbjct: 2076 PQPFDIKLNWLDKVLATVETPHHNLN---NICTGIDFLTFLTT----ILSPDQLVSIIRP 2128

Query: 2198 LEPSFNCKLPEIGNSLCTLLKM----VFEAFPVDASDTHQDVKLLHQKVEELIQKQLTTV 2253
            ++   +  +      +  L+ M    +   FP D    H+D+ LL+  V ++I + LT+ 
Sbjct: 2129 VQRGLSLCIIHQNTRIVRLMHMFLTRIMAIFPPDTQHKHEDLDLLYTAVSKMIAENLTSY 2188

Query: 2254 TSNPTQPPVEASVINVMISFTLNVLKTLVAGNKQYVDKFMLYLVRVFHRLARE-MATTSA 2312
              +P   P  +S+       TL +LK     N  Y+D+ ++  +RV + L R+ + T   
Sbjct: 2189 EKSPQ--PNASSLFG-----TLMILKACTTNNASYIDRILVQFIRVLNHLTRDHINTIGG 2241

Query: 2313 QLARQQGHRPEADATNQTGRGSADLSLSVNNLKTLMKLISERVLLLP-ESKRLFCQMLPT 2371
                 Q   P+++A        +            ++LI  R+ ++  E ++LF   +  
Sbjct: 2242 NTVISQS--PDSNALPLELLVLS------------LELIKNRIFVMSVEIRKLFIGTILV 2287

Query: 2372 VLGEKGTDTGVLLAILELVRDWVEHDFKGSNQVASTAPLVIKDVVAFMQRLAQVDCSGMT 2431
             L EK T+  ++  I++++ +W++        V +  P  I++  A + +L Q      T
Sbjct: 2288 SLIEKSTEVKIIKCIIKMLDEWIK---TKEPNVMTQVP-SIREKSALLVKLMQNVEKKFT 2343

Query: 2432 PAVLEEWDRMYLKLLHRLCSDTTKYNLSVRQEVFQKVERQFMLGLRSRDPEMRQKFFTLY 2491
              +  E +  +L++++ +  D     +  + E+  K+E  F+ GLR ++P +R KFF + 
Sbjct: 2344 DEI--ELNIQFLEIINFIYRD----EILKQTELTNKLEGAFLNGLRFQNPNVRSKFFEIL 2397

Query: 2492 HDSISKTLFTRLQYIIQTQEWEALSDVFWLKQCLDLLLAILVEHEPITLAPNSAQVPPLM 2551
              S+ + L  RL YII +Q W+ +   +W+KQC++LL+        I  +    ++P + 
Sbjct: 2398 DSSMRRRLHDRLLYIICSQAWDTIGSHYWIKQCIELLILTANTMMQIQCSNEQFKIPSI- 2456

Query: 2552 ASGVVPERAGMQLQA-------------------------------CDPPDESDGATP-- 2578
             + V+P  +    +                                 D  ++     P  
Sbjct: 2457 -TSVIPVNSSETQENSFVSFLSSHSESFDIIQTVDDKDDVYDIDLNADRKEDCQQILPNR 2515

Query: 2579 --TFMGIVNKHARFLNEVSKLQVADLVMPLRELAHTDAHVAYHMWVLVFPIVWATLQKEE 2636
              T + +V K A FL     ++   +++   +L H D  +A  +W+ +FP +W+   +++
Sbjct: 2516 RVTLVELVYKQAEFLEANRNIRTDQMLVATSQLCHIDTQLAQSVWLSMFPRIWSIFTEDQ 2575

Query: 2637 QVMLAKPMITLLSKEYHSKQLDKRPNVVQALLEGLSLSQPQPKIPSELIKFLGKTYNAWH 2696
            +  + K +I  LS   +  Q D  P+ +   +E L+   P   IP  L+ +LGK++N WH
Sbjct: 2576 RCNITKELIPFLSSGTNVNQKDCHPSTLNTFVESLTKCAPPIYIPPNLLAYLGKSHNLWH 2635

Query: 2697 IAISLLESHV-------------------MLFPQETRCFDALAELYRMLNEEDVRYGLWK 2737
             AI +LE                      +   Q    FD+L+++Y  ++EED+  GLW 
Sbjct: 2636 RAILVLEDMAVNQSMQSKDIDGGENQFSDLDVQQSNNIFDSLSKMYSSMHEEDLWAGLWL 2695

Query: 2738 RRTITADTRAGLSLLQHGLWQRAQDVFYNAMNKATQGSYNAGVVS---KAEMCLWEEQWV 2794
            +     +T   +S  Q G ++ AQ  +  AM K  Q   N GVV+    +E+ LWE  W+
Sbjct: 2696 KFAHYPETNIAVSYEQMGFFEEAQGAYDLAMTKFKQDLSN-GVVNTYVNSELLLWENHWM 2754

Query: 2795 ACAKRLSQWDILVDFGRSV--ENYDILLDTLIKVPDWTLLKETVLPKAQV---DESPKFR 2849
             CAK L+QWDIL+D+ ++   +N  ++L++  +VPDW L+K  +    Q        K  
Sbjct: 2755 RCAKELNQWDILLDYAQTNKDKNMFLILESSWRVPDWNLMKIALAKTEQCYLKHYGFKIN 2814

Query: 2850 MVQAYVALNDGSLASVTEADGRVGQGVELA----LHQWWQLPEMAVQSHIPXXXXXXXXX 2905
            + + Y+++    L       G + + VE+A    + +W +LP +    H+P         
Sbjct: 2815 LYKGYLSI----LHQEERQTGNIERYVEIASSLCIREWRRLPNIVSHIHLP--------- 2861

Query: 2906 XXXXSARVLLEIGNGNKPQPQGSGQVAGIQGPAGAYVDLKDILETWRLRTPNEWDELTVW 2965
                +++ ++E+   ++   QG  Q         +  D+K I++TWR R P   D+L+ W
Sbjct: 2862 -YLQASQQIMELHEASQIH-QGLAQSRN-----NSLHDMKAIVKTWRNRLPIISDDLSHW 2914

Query: 2966 MDLLQWRNHMYNTVINAFKGFSETNPQLHQLGFRDKAWSVNKLAYVARRQGLYEVCVSVL 3025
             D+  WR H Y  +    +  S+    +  LG    A ++     +AR+  L  VC   L
Sbjct: 2915 SDIFTWRQHHYQIITQHLEQQSDQGSTM--LGVHASAQAIISFGKIARKHNLTGVCQETL 2972

Query: 3026 NKMYGFLTMEVQEAFVKIREQAKAYLEM-----KGELASGLSLINTTNLEYFPLQHKAEI 3080
            +++Y   ++ + + F KIR+Q K YL+M     K E+   L +I +TNL+YF  +  AE 
Sbjct: 2973 SRIYTIPSVPIVDCFQKIRQQVKCYLQMPSTSGKNEINEALEVIESTNLKYFTGEMNAEF 3032

Query: 3081 FRLKGDFLQKMNDMENANQAYCTAISLYKHLPKGWISWGNHCDQVY-KETNEDLWLEYAV 3139
            + LKG  L ++   E A +++  A  L+  L K W  WG++ +Q++ KE    L ++ A+
Sbjct: 3033 YALKGLLLAQIGRSEEAGKSFSVAAQLHDGLTKAWAMWGDYMEQIFLKERKITLAVD-AL 3091

Query: 3140 SCFLQGIKYG-SKHGRNHLARVLFLLSFDNQTGSVSKAFDKYCDSIPQWVWLAWIPQLLL 3198
             C+LQ  +       R ++A+VL+ LS+DN T  +    +K+   IP   WL WIPQLL 
Sbjct: 3092 ICYLQASRNQIESKTRKYIAKVLWFLSYDNNTKILISTLEKHVAGIPPSYWLPWIPQLLC 3151

Query: 3199 SLQRPEAASCKNVILKLAAVFPQALYYWLRT-YLLERRDIANKPDMMRGTSNRTLAQVSS 3257
             L++ E     N++ ++  ++PQA+Y+ +RT YL  + +   K          + + +  
Sbjct: 3152 CLEQFEGDVILNLLSQIGRLYPQAVYFPIRTLYLTLKIEQREKHKTAEQAVKSSCSNIDG 3211

Query: 3258 TNVSNFANSSDVAASPATN 3276
            T +S F   +     P+ N
Sbjct: 3212 TTLS-FGRGASHGNIPSIN 3229



 Score =  161 bits (407), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 125/468 (26%), Positives = 212/468 (45%), Gaps = 34/468 (7%)

Query: 3459 KREFERDLDPDSASTFPATLAELTEKLKTWKGVLQSNVEDRLPAVLKXXXXXXXXXXF-- 3516
            K +F  D D          L  L  KLKTW  VL++ V+ +LP              F  
Sbjct: 3359 KEQFTNDFDFSKPGAMK--LHNLISKLKTWIKVLETKVK-KLPTSFLIEDKCRFLSNFSQ 3415

Query: 3517 HVLDIEVPGQYFNDQEVAPDHTVKLDRIGADVPIVRRHGSSHRRLTLVGNDGS-QKHFLV 3575
               ++E+PG+      ++  + V++ R    V IV+++ ++ RRL + G +G    + +V
Sbjct: 3416 KTAEVELPGELL--IPLSSHYYVRIARFMPRVEIVQKNNTAARRLYIRGTNGKIYPYLVV 3473

Query: 3576 QTSLTPSARSDERMVQLFRVLNRLLDKHKESRRRHLAFNTPIIIPVWPQVRLVEDDLMYS 3635
              S    AR +ER++QL R+LN  L+K KE+ RR L    P ++P+ PQ+RL ED+    
Sbjct: 3474 LDSGLGDARREERVLQLKRMLNYYLEKQKETSRRFLNITVPRVVPISPQMRLAEDNPNSI 3533

Query: 3636 TFGEVYEINCARYGREADLPITHFKERLNQA-ITGQLNLEALVDLRLHTYNEITNRFVSE 3694
            +  ++++  C     + D+PI  + +RL++    G      L+      ++EI    V +
Sbjct: 3534 SLLKIFKKCCQSMQVDYDMPIVKYYDRLSEVQARGTPTTHTLLR---EIFSEIQWTMVPK 3590

Query: 3695 NVFSQFMYKTLPTCNHLWTFKKQFAVQLALSGFMSYMLQIGGRSPNKILFAKNTGKVFQN 3754
             +   +  KT       W F+K   +QLAL+    + L +   + + +   +++G    N
Sbjct: 3591 TLLKHWALKTFLAATDFWHFRKMLTLQLALAFLCEHALNLTRLNADMMYLHQDSG--LMN 3648

Query: 3755 DFHPAYDIHG---MVEFAEPVPFRLTRNLQTFFTPFGVEGLFISSMCAAAQAVVAPKNQH 3811
              +  +D++     +    PVPFRLT N+  F T FG+ G   +++ A A+  + P N  
Sbjct: 3649 ISYFKFDVNDDKCQLNQHRPVPFRLTPNVGEFITHFGITGPLSAAIVATARCFIQP-NYK 3707

Query: 3812 VKHQLAMFFRDELIXXXXXXXXXXXXANGTAGGMSSAELKTK----VAENVEQVITRVQK 3867
            +   L    RDE+I              G+    S           V   V+ ++TR  K
Sbjct: 3708 LSSILQTILRDEIIALQKKGFRECKLIEGSEDRYSDGNCMEHSVNIVNSAVDIIMTRFNK 3767

Query: 3868 IAPQCFPEEEENSTEPPQSVQRGVSDLVDAALRPKSLCMMDPTWHPWF 3915
            I+   + +  EN         + +S LV +A    +LC MDP WHPW 
Sbjct: 3768 IS---YFDSIEN---------KKISVLVQSATNIDNLCRMDPAWHPWL 3803



 Score = 65.1 bits (157), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 42/125 (33%)

Query: 80  EILNRLPHSEVLRLFVQDLLKLSMHVLACDNEENGLICLRIIFDLHKNFRPALEPD---- 135
           E+++RLP +E LR  V+ ++ + + +L  DNEEN L+CLRII +LHK+FRP+   +    
Sbjct: 146 EMIHRLPITESLRQHVKTIITMMLKILKTDNEENVLVCLRIIIELHKHFRPSFNSEGMVE 205

Query: 136 --------------------------------------VQQFLDFVREIYQNFRATVTYF 157
                                                 +Q FL FV+EIY N    +T  
Sbjct: 206 IPKERLDESHALEVIVTDLCGPFFYKPEACNKAPVKCYIQLFLGFVKEIYTNLPNHLTSI 265

Query: 158 FEESS 162
           FE S+
Sbjct: 266 FETSN 270

 Score =  513 bits (1320), Expect = e-144,   Method: Compositional matrix adjust.
 Identities = 324/958 (33%), Positives = 500/958 (52%), Gaps = 82/958 (8%)

Query: 1280 PLRSKHAEQQVGTVMALNFCLALRP-PLLKMRQELSNILQESLQIAEADESVLNGK---- 1334
            PL+S     Q G +  L FCL+ +P PL+++  +   +LQE L +A  DES    +    
Sbjct: 1645 PLKSLSISLQTGVIDGLTFCLSQKPSPLIEIGADTVRVLQECLNVA-GDESSPTQQSQIK 1703

Query: 1335 FMNPKMAATLTKLRTVCIELLCTAMAWADFKTQSHAELRSRIIAMFFKSLTCRTPEIVAV 1394
              + K  +    LR   +E++ TAM   DF      E ++RII MFFK +T R  E+   
Sbjct: 1704 SSSAKSISATNNLRVCGVEMVATAMTCPDFLQFECLEFKNRIIRMFFKVVTARNKEMAMA 1763

Query: 1395 AKEGLRQVIQQQKMPKELLQSSLRPILVNLAHYKNLTMPXXXXXXXXXXXXSNWFNVTLG 1454
            AK GL   IQQQ++ ++LLQ+ LRP+L N+   K+L++P            SN FN  LG
Sbjct: 1764 AKRGLANSIQQQRLHRDLLQTCLRPVLSNITDPKSLSVPFLQGLSRLLELLSNCFNAALG 1823

Query: 1455 EKLMEHLKKWLEPEKLSSSQKSWKAGEEPKIAGAIIELFHLLPPAAQKFLDQLVTLTMQL 1514
            EKL E+LKK+ E  KLS     ++  EE KI  +II++FHLLPPAA K LD  + LT++L
Sbjct: 1824 EKLFEYLKKFEEAGKLSYLANKYRDSEEVKICASIIDIFHLLPPAA-KLLDSTIILTIRL 1882

Query: 1515 EAALPPSQVYSELNSPYRLPLTKFLNRYAPEAVDYFLGRLTQPTVFRRFMDIIQSEGGQP 1574
            E +L       E+ SPYR PL +FL +Y    ++ F+G+L Q  +  R + +      +P
Sbjct: 1883 EQSL-----CKEVTSPYREPLIRFLAKYPQRTIEIFMGQLPQFNLIFRLI-LKHQPLSKP 1936

Query: 1575 LREELARSPNKIIQSAFPAVEENXXXXXXXXXXXXXXXXXXXXXQATAEAQFQGVALVSA 1634
            + EELA + +  +++   +                           +A+ +F  +++VS 
Sbjct: 1937 IVEELANTYSIWLEAHLKS--------------------------PSADIRFHTLSMVSI 1970

Query: 1635 LVKLLPDWLHQNRAVFDALVRLWQSPARQARLI-NEQGLSLNQVKESKRLVKCFLNYLRH 1693
            + K LP+WL +NR V D L+  W+  +   +   N   +S   ++E+K +VKCFL Y + 
Sbjct: 1971 IRKQLPNWLPENRKVLDILIEYWRPLSHMIQSASNPLDISNQTLRETKIIVKCFLQYCKA 2030

Query: 1694 DKAEVNVLFEMLSIFLVRTRIDYTFLKEFYMVEVGEGYSPQEKKAVLLCFLELFQTKRLP 1753
               E ++ F MLS+  +R  +D+ FL+++Y  ++    + ++KK ++  FL  F+ + +P
Sbjct: 2031 HSEETDLYFYMLSVLTLRASMDFNFLRDYYQHDLAPSSTIEQKKKIIQTFLIFFKDQTIP 2090

Query: 1754 QDVLVVAMQMLILPMLTHSFQQ-----NQCWDVVDATIIKTIIEKLLDPPEEVSADYDES 1808
             D  V A+Q LI P+LT+ F Q     +    +++ ++   + ++ L+   EV A YD++
Sbjct: 2091 SDNKVQAIQNLITPILTNYFHQTDRNSSSGGGIIEDSLFIQLTKQTLE--TEVKASYDDT 2148

Query: 1809 XXXXXXXXXXXXXXXXPSDLVHHRKELIKFGWNHLKREESASKQWAFVNVCQFLEAYQAP 1868
                             S LV  RKELIKF WNHLK E+   KQ A++  C F+EAY+ P
Sbjct: 2149 LLIELLQLETLLVKNLSSVLVDCRKELIKFAWNHLKNEDLTCKQSAYILACGFIEAYETP 2208

Query: 1869 EKIILQVFVALLRTCQPEHRVLVKQALDILMPALPRRLPLGENKIPIWIRYTKKILVEEG 1928
             KI+LQV+V LLR  QPE + LVKQALDILMP    RLP G+ K   W+++TKKI+VEEG
Sbjct: 2209 HKIVLQVYVPLLRAYQPESKHLVKQALDILMPCFKTRLPGGDPKNSTWVKWTKKIIVEEG 2268

Query: 1929 HSVPNLIHIFQLLVRHANLFYNCRAQFVPQMVNSLSRLGLPQNTPLENRRLAIDLAGLVV 1988
            H+   L+HI QL+VRH  LFY  R+QFVP ++  L ++ L  N   EN++L+ID+A  ++
Sbjct: 2269 HTTAQLVHIIQLIVRHPQLFYPSRSQFVPHIILLLPKIALGSNLTAENKKLSIDIADTII 2328

Query: 1989 MWEKRRQAEAKGSSTEGDGQSKSAGAEGQVPAEAIAAGGAPSGTKRTAEAAGLTGVGDEA 2048
            +WEK R +  + S         +         +   +   P  T              E 
Sbjct: 2329 IWEKMRMSNLQQSIKTSSSSLPTTTTTTTSSNKPTDSSSLPPNTPIA-----------EG 2377

Query: 2049 SKRTKSESGLPGLAGMSPNLPTGPTNSIPNIGTPGSMGQADEEFKPNAAMEEMIINFLIR 2108
            S  T S+ G+      +PN+    ++S P  G        D+E++P  +  E I  FLIR
Sbjct: 2378 SITTPSQGGVA-----TPNV----SDSTPTPGIHHGATNIDDEYRPPLSAIEHISLFLIR 2428

Query: 2109 VALVTEPKDKETQAMYKQALELLTQALEVWPHANVKFNYLEKILSAQQPAGQSKDPATAL 2168
            +A            + ++  ELL Q L +WP  N+KF+  EK ++  QP          +
Sbjct: 2429 MA-------SNWYHINEKCSELLRQTLVIWPETNIKFSVFEKPMNTDQPQ--------MI 2473

Query: 2169 AQGLDVMNKAVEKQPHLFIRNNVHHIIQVLEPSFNCKLPEIGNSLCTLLKMVFEAFPV 2226
            +  L ++N   E Q + FI NNV  + Q L  + N    +I + L +L K +  AFP+
Sbjct: 2474 STCLSMLNLIAEYQVNTFIPNNVVALQQSLLQALNSDNAKISSLLGSLFKKILAAFPL 2531



 Score =  316 bits (809), Expect = 2e-84,   Method: Compositional matrix adjust.
 Identities = 190/677 (28%), Positives = 329/677 (48%), Gaps = 109/677 (16%)

Query: 2659 KRPNVVQALLEGLSLSQPQPKIPSELIKFLGKTYNAWHIAISLLESHVM----LFPQETR 2714
            + PNV++  +E L + +P PK+P E+I FLG+ YN W+ AI ++E  ++    L      
Sbjct: 3160 REPNVIKTWMETLGMCKPIPKVPIEVISFLGENYNCWYYAIRMIEQQLIDRQKLLDSTDI 3219

Query: 2715 CFDALAELYRMLNEEDVRYGLWKRRTITADTRAGLSLLQHGLWQRAQDVFYNAMNKATQG 2774
             +D L+ LY  + E+D+ YG++++R    +T+ GL L Q  ++Q +Q+VF +AMNK +  
Sbjct: 3220 NWDYLSYLYGAIGEKDLLYGIYRKRYQCDETKLGLLLEQFYMFQSSQEVFLSAMNKYS-- 3277

Query: 2775 SYNAGVVSKAEMCLWEEQWVACAKRLSQWDILVDFGRSVENYDILLDTLIKVPDWTLLKE 2834
            +       ++E  LWE+ W+ CAKRL+QW+ + +F +    YD+ +++  K+P W  +KE
Sbjct: 3278 AVGCKPTPRSENLLWEDHWLECAKRLNQWNFVHEFSKEKNMYDLTIESAWKIPQWNSVKE 3337

Query: 2835 TVLPKAQVDESPKFRMVQAYVALNDGSLASVTEADGRVGQGVELALHQWWQLPEMAVQSH 2894
             +       ++   +++Q Y   N+       E D  +    +L L +W  LPE + +SH
Sbjct: 3338 NMKKMMSQGDTSIRKILQGYFLTNEKRYH---EVDPAIVTSNQLILDKWVSLPERSFRSH 3394

Query: 2895 IPXXXXXXXXXXXXXSARVLLEIGNGNKPQPQGSGQVAGIQGPAGAYVDLKDILETWRLR 2954
                           S  +L EI N    Q     Q A +         +K I   WR R
Sbjct: 3395 TNSLVEMQQVVELQESVHILKEISNITLSQ-----QPADLSRSFLTSNYIKSIFNIWRER 3449

Query: 2955 TPNEWDELTVWMDLLQWRNHMYNTV----INAFKG------------------------- 2985
             PN+ ++L +W +L+ WR  ++N +    +N   G                         
Sbjct: 3450 LPNKDEDLLIWFELMAWRQQVFNIIGTPSMNGGIGANPVTPTNTTTTITNPDGTTTTTTT 3509

Query: 2986 -FSETNPQLHQLGFR-------DKAWSVNKLAYVARRQGLYEVCVSVLNKMYGFLTMEVQ 3037
                    ++Q+ F        + AW++NK +++ R+  + EVC++ L+KM+  L +E+ 
Sbjct: 3510 PLPPPQQPINQIEFASPRYMVLEMAWTMNKYSHIVRKHNIIEVCLNSLSKMFD-LQIELH 3568

Query: 3038 EAFVKIREQAKAYLEMKGELASGLSLINTTNLEYFPLQHKAEIFRLKGDFLQKMNDMENA 3097
            + F+ ++EQ K YL++     +G+S+IN+TNL++F    K E  +LKG+FL ++   + A
Sbjct: 3569 DIFLNLKEQIKCYLQLPTHYDTGISIINSTNLDFFTPMQKGEFLQLKGEFLNRLGRYDEA 3628

Query: 3098 NQAYCTAISLYKHLPKGWISWGNHCDQVYKETNEDL-----------------WLEYAVS 3140
            NQ++ +++S Y++  K WISW + CD  +  TN                    W E A+S
Sbjct: 3629 NQSFASSVSQYENSAKNWISWAHFCDNQF--TNHSSSSITPSSTPTTYDIKTQWAESAIS 3686

Query: 3141 CFLQGIKYGSKHGRNHLARVLFLLSFDNQTGSV--------------------------- 3173
            C++QGIK   K+G  ++ R+ +LL + N +G V                           
Sbjct: 3687 CYIQGIKCDPKYGSRYVPRIFWLL-YLNGSGEVPQQIQTQQQQQQAAAQGGLPPQPRKLT 3745

Query: 3174 --SKAFDKYCDS---IPQWVWLAWIPQLLLS----LQRPEAAS-CKNVILKLAAVFPQAL 3223
                 F  + +S   +PQW+WL ++PQL+      L  P     C  +I K+  +FP + 
Sbjct: 3746 PAQSVFQSFLNSWTILPQWIWLNYMPQLISGAANLLNFPGYGFLCWQMIGKICYLFPNSS 3805

Query: 3224 YYWLRTYLLERRDIANK 3240
            YY  R  +LE +  A+K
Sbjct: 3806 YYHFRKLVLEMKSNASK 3822



 Score =  226 bits (577), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 184/715 (25%), Positives = 338/715 (47%), Gaps = 112/715 (15%)

Query: 195 QSTRSFKVVTECPLIVMFLFQLYPRYVPTNIPLLLPLMVSAIGIPGPTEVPPTLKNVYAE 254
           +S  SFK++TECP++V+ LFQLY  Y+ +N+P  +PL++  + +  P     T  + Y +
Sbjct: 304 KSIESFKILTECPIVVILLFQLYNSYMSSNVPKFIPLIIETLSLQAPANSTVTHHSQYVD 363

Query: 255 LKGAQVKIDASIAGMFIGIFLCWLQTVSFLTYLLRSFADCIRPHEDXXXXXXXXXXXXCP 314
              AQVK                  T+  L Y+L+   + I+ + D            CP
Sbjct: 364 FIAAQVK------------------TLYLLAYVLKWHIEQIKQYSDRFPRSVIQLLQNCP 405

Query: 315 -DSVSIRKELLVATRHVLATDFRRGFFPQIDTLLDERVLVGTGRACYETLRPLAYSLLAE 373
             S +IRKELLV  RH+L++DF+  F   +D LLDE++++GT R  YE+LR +AY  LA+
Sbjct: 406 AHSSAIRKELLVTLRHILSSDFKSKFIVYLDLLLDEKIILGTSRTSYESLRSMAYGSLAD 465

Query: 374 LIHHVRLDLSLPQLSRIVYLFSRNVHDSSLPLSVQTTCVRLMLNLVETIFGRRVDHLSRE 433
            IH++R +L++ Q+S++V ++SR++HD + P+S+Q   V+L+++L++ I  +R       
Sbjct: 466 FIHNMRNELNINQISKVVAIYSRHLHDQTNPVSIQIMSVKLIISLMDVI--QRKQDPPEY 523

Query: 434 EGRALLGRILDAFVSKFGTLKHSIPQLLEEDGEDR----KERRTLRSRLELPVQAALNLQ 489
           + R+++ +++++F++KF +LK SIP+LL +  +++    K+ ++L+ +L+    A     
Sbjct: 524 KSRSIIYKVIESFINKFSSLKRSIPKLLADQQKEKEKELKDPQSLKDKLDGLSSANTTTS 583

Query: 490 VPPEHS--KEVMDCKQLLKTLIMGMKTLVWSITHFNATPLPQ------------------ 529
              E      V D + L+KT+   ++ + WS++   A P+ +                  
Sbjct: 584 STGEIIILDPVKDTRTLIKTMTSSLRNIFWSLS---ACPINKPGTGITTGAGATTTTTTN 640

Query: 530 ---MNNAPVPVKGMREEEVRLASGILKSGLHCLALFK----EKDEEKEMYTHYSSVFAVM 582
                  PV +     EE  L   + KS + C  ++        EEKEM  ++++ F ++
Sbjct: 641 TNNTIIPPVRIALPSIEESLLFIKLFKSTVKCFPIYGGCNPSPQEEKEMIENFTASFMML 700

Query: 583 EHRNLMDMFSLCMPQLFDCMLANLQLLQI----FSTLLYTP---KVTKHFADVLVNYLVT 635
           + R   ++ +  +P L+   L N  LL I     S     P   ++ + F +VL  +L  
Sbjct: 701 DQRTFQEVSTFILPFLYQRSLNNPSLLLIPQGFLSVTQMNPTGVQINRVFLEVLTPFLY- 759

Query: 636 SKLDTLKQPDTPAAKLVLQLFRYLFVAV-------------------------------- 663
            K+  L+  D P   ++ +L + +F A+                                
Sbjct: 760 EKIRNLQPTDKPDICMI-KLIKLIFNAIQPNNNSGVGGSGGSNSSGGGGGGGSNSSNNST 818

Query: 664 -----AKFSADCERVLQPHVITLMESCMKNATEVEKPLGYMQLLRTMFRALS----GGKF 714
                    + C + +   +I ++   +  + +++  + Y+ LL+T+F++ +      + 
Sbjct: 819 NSNTTTNIDSTCVQQVLSSMILILLKLITESKQIDS-IQYLLLLKTIFKSCTRPDQSKEI 877

Query: 715 ELLFREFIPTLQPCLNMLLAMVEGPTGLDMI-DLVVELCLTXXXXXXXXXXXXXXXMKPL 773
            LLF    P +   LN LL      T +  +  L++EL L+               +KPL
Sbjct: 878 TLLF----PIILETLNDLLLSSSHSTMIPAVQQLLIELSLSIPVQIATLLPSLHLLVKPL 933

Query: 774 VLALGGSDELVAL-GLRTLEFWIDSLNPEFLEPSMATVMSDLILTLWSHLRPKPY 827
           +LAL  S   +     R LE  +D+   +FL  +     S+ +  L  HLRP PY
Sbjct: 934 MLALDSSSSELLSTTFRILELIVDNATGDFLLFTFRDNKSEFLQILSKHLRPAPY 988



 Score =  138 bits (347), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 72/152 (47%), Positives = 104/152 (68%), Gaps = 3/152 (1%)

Query: 5   ANFEQHARRFLEQDLSMQNR--LTLATEVRDSIEIVHTSEYLNFLKSYFVVFSNLLTKIT 62
            NFE +ARR  E + + +    L L TE+RD+IE+VHT EY  FL   F VF N+L +  
Sbjct: 54  VNFESYARRCFELNNNNEQTQLLALVTEIRDNIELVHTVEYPTFLNFLFPVFYNILRQ-G 112

Query: 63  KPQATDNVEHKLRNVVIEILNRLPHSEVLRLFVQDLLKLSMHVLACDNEENGLICLRIIF 122
             Q  D  E K+RN +++ILN+LP++E+LR  +  LL+LSM++L  DNEEN L+CLRII 
Sbjct: 113 AVQFNDGPEQKIRNTILDILNKLPNNELLRPHILVLLQLSMYLLEVDNEENALVCLRIII 172

Query: 123 DLHKNFRPALEPDVQQFLDFVREIYQNFRATV 154
           +LHKN+R ALE ++Q FL+ V ++Y +  +T+
Sbjct: 173 ELHKNYRNALESEIQPFLNIVLKLYTDLPSTI 204



 Score = 89.0 bits (219), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 99/459 (21%), Positives = 191/459 (41%), Gaps = 74/459 (16%)

Query: 3521 IEVPGQYFNDQEVAPDHTVKLDRIGADVPIVRR-HGSSHRRLTLVGNDGSQKHFLVQTSL 3579
            +E+PGQY  +++   ++ VK++++G    +++  +G    R+TL G +G    FL+++S 
Sbjct: 4134 LEIPGQYNTNRDPNIENNVKVEKVGMFAKLIKHSNGMVCPRITLYGGNGKAYQFLIESS- 4192

Query: 3580 TPS-------------ARSDERMVQLFRVLNRLLDKHKESRRRHLAFNT-PIIIPVWPQV 3625
             PS             AR  ER  QL   +N +L K++E+RRR L  N+ P ++P+   +
Sbjct: 4193 -PSLINGITNSNNNNVARVYERKNQLLGSINSMLIKNRETRRRGLTLNSYPTVVPIKNSL 4251

Query: 3626 RLVED--DLMYSTFGEVYEINC--------------------------ARYGREADLPIT 3657
             ++++  +       EV+  +                           ++  ++ DL  T
Sbjct: 4252 TMIQNIGNDSIKQLAEVWYTHSNQSNLFKPMLKYKEMLLNSNLHTELLSKKDQDGDLEFT 4311

Query: 3658 HFKERLN---------QAITGQLNLEALVD-LRLHTYNEITNRFVSENVFSQFMYKTLPT 3707
            +  E  N          + +       ++D  +L  + E++     E + +      LPT
Sbjct: 4312 NITEDNNISSSSSSSSSSGSNSGENSPIIDSSKLVVFREMSKEIGDELMINYIQSTLLPT 4371

Query: 3708 -CNHLWTFKKQFAVQLALSGFMSYML--QIGGRSPNKILFAKNTGKVFQNDF-------H 3757
                 + FK  F+ Q  L   + Y+L   IG   P+KI   K+TG V+ ND+        
Sbjct: 4372 NYQDQYEFKLNFSNQFGLHSLLQYILFSDIGDIDPSKIYLTKSTGSVYYNDWSLKLTNRK 4431

Query: 3758 PAYDIHGMVEFAEPVPFRLTRNLQTFFTPFGVEGLFISSMCAAAQAVVAPKNQHVKHQLA 3817
              +D+     + +    RL+ N++ +  P  +EG ++SSM +    +   K+Q V + + 
Sbjct: 4432 LGFDLLQDNPYNQQQLLRLSPNIRNYLGPLYLEGSYLSSMISTCICLSDLKDQLV-NSIN 4490

Query: 3818 MFFRDELIXXXXXXXXXXXXANGTAGGMSSAELKTKVAENVEQVI-TRVQKIAPQCFPEE 3876
            +F  DE +             N         E   K    V Q++  R+  + P   P++
Sbjct: 4491 LFIFDEYMCMNNVEPLQQSEQNKDRN--IHYEFIDKTTATVHQMLENRIDSLTPSSQPDK 4548

Query: 3877 EENSTEPPQSVQRGVSDLVDAALRPKSLCMMDPTWHPWF 3915
                T     + + V+ L+  +L   ++  +D    PW 
Sbjct: 4549 ----TCFISPIVKKVNQLIQNSLS-SNISQLDQLSCPWL 4582



 Score = 70.5 bits (171), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 51/140 (36%), Positives = 80/140 (57%), Gaps = 10/140 (7%)

Query: 2410 LVIKDVVAFMQRLAQVDCSGMTPAVLEEWDRMYLKLLHRLCSDTTKYNLSVRQEVFQKVE 2469
            L IK+ + F+ +L +VD   ++ A   E    Y KL+    S  ++ N S +QE+ Q +E
Sbjct: 2803 LTIKEKINFLIKLGRVD--QLSNA---ELSLSYYKLV---LSFYSESNSSSKQELSQ-LE 2853

Query: 2470 RQFMLGLRSR-DPEMRQKFFTLYHDSISKTLFTRLQYIIQTQEWEALSDVFWLKQCLDLL 2528
              FM+GLR+  D  MR+  F + H SI  T + RL YII  Q+W+ L   +W+K  LDLL
Sbjct: 2854 PCFMMGLRNTVDQGMRKSLFNILHKSIGTTPYQRLNYIIGVQQWDILGTTYWIKHALDLL 2913

Query: 2529 LAILVEHEPITLAPNSAQVP 2548
            LAIL   + + ++   +++P
Sbjct: 2914 LAILPNDKFVKISNFCSKLP 2933