Score =  622 bits (1605), Expect = e-178,   Method: Compositional matrix adjust.
 Identities = 373/1005 (37%), Positives = 540/1005 (53%), Gaps = 116/1005 (11%)

Query: 2627 LELVREAMAAELRVLRQDKYGWILHAENGWADHLQQLVHERGIWPIVPEVCDEEPDWQLC 2686
            + +VR+ +  + +  ++ +   + +    W     +L+ ERG+W   P +      W L 
Sbjct: 2314 IAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWG--PPIGSHLDKWMLE 2371

Query: 2687 PTEGPYRMRKKLERRKKNLSILGKSQLMEERQNDGVYKVSPNDGVNPLDKENPLHDQYVD 2746
             TEGP RMRKK+ R                  ND  Y   P           P  +Q   
Sbjct: 2372 MTEGPCRMRKKMVR------------------NDMFYNHYPY---------VPETEQEAS 2404

Query: 2747 LFSSDTQKR-LGYSSKEFLASLEEDIGELKTEIGDDEEDMLSARVNWNEESFSGNSESQR 2805
            +      +R + Y SKE+   L      +        +D +        ES  G +  Q 
Sbjct: 2405 VGKPARYRRAISYDSKEYYLRLASGNPAIV-------QDAIV-------ESSEGEATQQE 2450

Query: 2806 PKAM--SVASLKLAGEEVIDQVLGSPHGSVSPAVEEIMPE--EANYLEQEMHEDGEYLIR 2861
            P+    ++A +K   +  + +   +P G      E++  +  E+  +E+E   D   L+R
Sbjct: 2451 PEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSIEEEEKTDNATLLR 2510

Query: 2862 PHLERGERIRFRYNCERVVGLDKRDGIFLIGEKCLYVIENYIIDENKCIKEKGEERDLSI 2921
              LE GE+I+  Y C RV GLD  +G+ L G++  YVI+ + +   +      E RD+  
Sbjct: 2511 -LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATR------EIRDIET 2563

Query: 2922 IDQALGVRANSTGVVDMNISKQTEVAADSWAGGRAWAYSGGAWGKEKVKAGQNMPHPWRM 2981
            +   +                                  G   G  ++K          +
Sbjct: 2564 LPPNMH---------------------------EPIIPRGARQGPSQLK------RTCSI 2590

Query: 2982 WKLESVHELLKRRYQLRPVAIELFSMDGCNDLLVFHKNERDEVFKTLLAMNLPRNSMLDT 3041
            +  E + E+ KRRY L+P+A+E+FS DG N LL F K  R++V++  LA+ +P  S+ D+
Sbjct: 2591 FAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAV-VP--SLTDS 2647

Query: 3042 TISAASKQ-----EAGEGGRLFKMMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYNDLTQ 3096
            + S + ++     E G G     +  KS ++RW+ GEISNFQYLMHLNTLAGR YNDL Q
Sbjct: 2648 SESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQ 2707

Query: 3097 YPVFPWILKDYTSEELDLSNPDTFRRLDKPMGALHPEREKEFRKRYETWEDP--EIPRFH 3154
            YPVFPWIL DY SEE+DL+NP TFR L KPMGA   ER  +++KRY+ WEDP  E P +H
Sbjct: 2708 YPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYH 2767

Query: 3155 YGSHYSSAGSVLFYLIRLPPFSQENKQLQGGAFDHADRLFNSIKDTYLSASQGNTADVKE 3214
            YG+HYSSA  V  YL+R+ PF+Q   +LQGG FD ADR+F+S+++ + SAS+ N ADVKE
Sbjct: 2768 YGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKE 2827

Query: 3215 LIPEFFYLPEFLENRFGFDFGVKQSGERVNDVLLPPWAKGSAREFVRKHREALESQYVSE 3274
            LIPEFFYLPEFL N   FD G KQ+G ++ DV+LPPWAKG  REF+R HREALE  YVS 
Sbjct: 2828 LIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSA 2887

Query: 3275 NLHHWIDLIFGFKQRGKPAVEALNVFYHLTYEGAVDIDRVPDPAMKAAVLAQINHFGQTP 3334
            +LH WIDLIFG+KQ+G  AVEA+NVF+HL YEG VDI  + DP  + A +  IN+FGQ P
Sbjct: 2888 HLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIP 2947

Query: 3335 KLLFTKPHPKRK----------WVQKQPLALALRNY--HL--LAPQ--EMRPLSSRVSQI 3378
            K LF KPHP ++           +   P A + + +  HL  L P    ++ L   V QI
Sbjct: 2948 KQLFKKPHPPKRVRSRLNGDNIGISVPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQI 3007

Query: 3379 VIFQDKVYAAGANRILKPPSFTKYLCWGFSDRSLRIISYEQERLLSTHENLHDDGPVLCT 3438
            V     + A   N++L PP++ K   WG++D S R+ +YE ++ ++ +E L + G +LC 
Sbjct: 3008 VCTDKGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILC- 3066

Query: 3439 GFSRDGRILVTGGADGVVSVWRQRKDXXXXXXXXXXXXXXCAHSQAVLCLAVSQPYSLIV 3498
                + ++++TGG   VV VW +                   H+  V C   S  Y +IV
Sbjct: 3067 AVCPNPKLVITGGTSTVVCVW-EMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIV 3125

Query: 3499 SGSKDRTVIFWDLSSLEYVRQLPELPEPPTAIHANDMTGEVVTAAGTTLSVWSINGDCLA 3558
            SGS+DRT I WDL+ L ++ QL     P +A+  N++TG++V+ AGT + VWSING+ + 
Sbjct: 3126 SGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIV 3185

Query: 3559 AVNTSHVAADTILSITSPHLSDWMEASWYVTGHQNGVIRLWHMEL 3603
            +VNT    +  I+      +++W   +  VTGH +GV+R W ME 
Sbjct: 3186 SVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEF 3230



 Score =  114 bits (286), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 102/418 (24%), Positives = 185/418 (44%), Gaps = 47/418 (11%)

Query: 1171 GDRTWPPTAGYSFVCWARFEKLSAQNGQNS-------SGAEASKELHRNRSGSLGSVLRI 1223
            G+R +PP +G S+ CW   E  S+    +          A +S++ +   +  L +  R 
Sbjct: 1090 GERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRS 1149

Query: 1224 LTVGTAEDKSSICAELFLSDSGVLTLATSPTSYLCFKGVRLEEGIWYHLTIVHNKPNALA 1283
            L V T E+      + F  +S    +      + C  G  + EG W+HL ++ ++     
Sbjct: 1150 LIVSTKEELLQNYVDDFSEESSFYEILPCCARFRC--GELVVEGQWHHLALLMSR----- 1202

Query: 1284 GLFQSSVAYLYLNGSLRHTGKLGYSAS----------PVGKPLQVTVGTSSSFSEVSPFT 1333
            G+ ++S A LYL+G L  T KL Y  S          PV   +   VGT  +  +++   
Sbjct: 1203 GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLV 1262

Query: 1334 WQLGSCYLFEEVLPAPAIFFMYVLGRGYRGLFQDTDMLRFIPYEACGGGNLMVLESLDTE 1393
            W+LG  +  EEVLP  ++  +Y LG  Y G FQ            C        E +   
Sbjct: 1263 WRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQ----------AVCVPCKDAKSEGVTPS 1312

Query: 1394 LLATLKAEGLSQNAGVAQLEGSGVIWDLEKLARFWAQLCGRHLIFAYDGSHAEDVVPAGV 1453
             ++ +  E +S   G+  L  S +   + ++ + + +L  + +      S  E+  P  +
Sbjct: 1313 PVSLVAEEKVS--FGLYALSVSSLT--VARIRKVYNKLDSKAIAKQLGISSHENATPVKL 1368

Query: 1454 MSMVNLVDPMSAAASVLGGLPRLARIHGDVHICT--PCNIADTMRKVGGVAVVLAMIEAA 1511
            +   N    ++  A  +G     A + G + + T  P  +A T++ +GG A +L ++  A
Sbjct: 1369 VH--NAAGHLNGPARTIG-----AALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMA 1421

Query: 1512 DSCETLHLALSVLVSMLQSNPRNARDMQACRGYHLLALFLHRRMDYFEARDLDFLFRI 1569
               E L+ A+  LV +++SNP  +++M+  +GY LLA+ L ++     +  L   F +
Sbjct: 1422 SDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSL 1479



 Score = 80.9 bits (198), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/112 (35%), Positives = 58/112 (51%), Gaps = 3/112 (2%)

Query: 3649 HKEPVTALSLGNDLKQLCSGDAGGHLVSWTLPDDGFKQTPSLEIEP---DQCTTCQKELN 3705
            H   VTAL +  D  ++  GD+ G + SW++ D   +      ++    D C+ C    +
Sbjct: 3391 HPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFS 3450

Query: 3706 LTEMKHHCRNCGQISCADCCNNHIVLEDLGYFSPVRVCGSCYESRQSCTGRQ 3757
            LTE +HHCRNCGQ+ C  C      ++ L   SPVRVC +CY S Q   G +
Sbjct: 3451 LTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAE 3502



 Score = 66.6 bits (161), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 76/347 (21%), Positives = 136/347 (39%), Gaps = 24/347 (6%)

Query: 591 IGDIEIVQTFQDVFLYTGNVMXXXXXXXXXXXXFASHPDNYVLVQERRTMPLFLQNMGSY 650
           + +I+     Q+ FL                  + +   NY +++ + T+  F + +   
Sbjct: 378 VRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKL 437

Query: 651 ALILQERLLKVLEYAVTVVNCIPEQELLSLCYLLQQPYASPLRKTVLSFFGKLLSFDRNY 710
             + Q +  ++LE+ V  +N IP +EL+S+  LL+   +       +    K    D  +
Sbjct: 438 PEV-QNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIF 496

Query: 711 KKVLREVGXXXXXXXXXRR-CGLSEDPISKDNAEPLVESPSLELHIFEDKVTIG-LAWEC 768
           K V REVG          +   L +DP    N     +  S      ED+  +  L  E 
Sbjct: 497 KDVFREVGLLEVMVNLLHKYAALLKDPAQALNE----QGDSRNNSSVEDQKHLALLVMEA 552

Query: 769 LLSLLKKSDGNQTVFRKANGVGYILPLVASASQRSGALRVLSCLICEDINQAHADELKSL 828
           L  LL+ S+ N  +FR+  G      +V     R  AL  +  L+   ++    D++ +L
Sbjct: 553 LTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLV---LSPNGEDDMGTL 609

Query: 829 LKIAHXXXXXXXXXXXXXLDIEAKEDILWCVWRILGANSTTRVVFGDGNGFGLLLSVLEG 888
           L + H              +++ K DIL  +  +L  +  +R VF    GF  + S+L  
Sbjct: 610 LGLMHSAPPT---------ELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVA 660

Query: 889 IHSGCNDPSVESIGDEAAPASSLAVHMEVLDALLHVITVAAAESPTN 935
           +    + P     G E    S +   +E+L  +   +T A    P N
Sbjct: 661 MERSLSSPPKN--GWEKVSQSQV---LELLHTVFCTLTAALRYEPAN 702

 Score =  609 bits (1570), Expect = e-173,   Method: Compositional matrix adjust.
 Identities = 338/872 (38%), Positives = 491/872 (56%), Gaps = 108/872 (12%)

Query: 2842 PEEANYLEQEMHEDGEYLIRPHLERGERIRFRYNCERVVGLDKRDGIFLIGEKCLYVIEN 2901
            P + +YL+  M +D      P L         YNC  V G+DK +GI +     +Y+ + 
Sbjct: 2795 PYDQSYLKDAMRKD------PRLNG-----IMYNCGSVDGMDKIEGILIFCPVYMYIFDG 2843

Query: 2902 YIIDENKCIKEKGEERDLSIIDQALGVRANSTGVVDMNISKQTEVAADSWAGGRAWAYSG 2961
            Y  DEN          D+S +++ +                              W   G
Sbjct: 2844 YYKDENTG--------DISEVEEKIN---------------------------SEWLPEG 2868

Query: 2962 GAWGKEKVKAGQNMPHPWRMWKLESVHELLKRRYQLRPVAIELFSMDGCNDLLVFHKN-E 3020
                 +K      + H +  W  E + ++LKRRY LR VA+E+FS DG N+L+V+     
Sbjct: 2869 TVLPMKK-----KIIHYFLKWAYEDIRDVLKRRYLLRQVALEIFSTDGRNNLVVYRDEPT 2923

Query: 3021 RDEVFKTLLAMNLPRNSMLDTTISAASKQEAG-------------------EGGRLFKMM 3061
            RDEV+ TL+      N     TI   ++   G                      R   + 
Sbjct: 2924 RDEVYHTLV-----NNVSSHNTIGGDAQGITGGQTGNDDNDDHHGGGGGRGVRDRFTSIW 2978

Query: 3062 AKS-FSKRWQNGEISNFQYLMHLNTLAGRGYNDLTQYPVFPWILKDYTSEELDLSNPDTF 3120
             KS  + +WQ G+ISNFQYLMHLNTLAGR YNDLTQYPVFPW+L DY SEELD+ +P  +
Sbjct: 2979 RKSPLTLKWQQGQISNFQYLMHLNTLAGRSYNDLTQYPVFPWVLSDYESEELDIDDPKVY 3038

Query: 3121 RRLDKPMGALHPEREKEFRKRYETWEDPE-------IPRFHYGSHYSSAGSVLFYLIRLP 3173
            R L KPMGAL   R ++FR+R+E W+D E       +P+FHYG+HYSSA  VL+YLIRL 
Sbjct: 3039 RDLSKPMGALEESRAQKFRERFENWDDQEPNEHGHKVPKFHYGTHYSSAAIVLYYLIRLE 3098

Query: 3174 PFSQENKQLQGGAFDHADRLFNSIKDTYLSASQGNTADVKELIPEFFYLPEFLENRFGFD 3233
            PF+Q   +LQGG +D  DRLF+SI + + S+SQG+T  V ELIPEF+YL EFL N   F+
Sbjct: 3099 PFTQHFLKLQGGRWDQPDRLFSSITEAWASSSQGSTGVVMELIPEFYYLDEFLVNNNKFN 3158

Query: 3234 FGVKQSGERVNDVLLPPWAKGSAREFVRKHREALESQYVSENLHHWIDLIFGFKQRGKPA 3293
            FG KQ GE ++D++LPPWAKGS +EF++ HR+ALES YVSE+LH WIDLIFG++Q+GK A
Sbjct: 3159 FGTKQGGEPIDDIILPPWAKGSPQEFIKLHRKALESDYVSEHLHEWIDLIFGYRQQGKAA 3218

Query: 3294 VEALNVFYHLTYEGAVDIDRVPDPAMKAAVLAQINHFGQTPKLLFTKPHPKRKWVQKQPL 3353
             ++LNVFY+LTYEGAV+ID + DP  KAA +AQIN+FGQTPK LF KPHPKR        
Sbjct: 3219 DDSLNVFYYLTYEGAVNIDAISDPVEKAATIAQINNFGQTPKQLFDKPHPKR-----NAT 3273

Query: 3354 ALALRNY-HLLAPQEMRPLSSRVSQIVIFQDKVYAAGANRILKPPSFTKYLCWGFSDRSL 3412
             + L  Y   L    ++ +   V QI +  D+    G N++L PP+ +KY+ WG  D S+
Sbjct: 3274 LMGLPFYAKALTGNFIKDIGEPVGQIRLINDRATCVGFNKVLLPPNHSKYMLWGLPDGSI 3333

Query: 3413 RIISYEQERLLSTHENLHDDGPVLCTGFSRDGRILVTGGADGVVSVWRQRKDXXXXXXXX 3472
            R  + ++ ++L  H     DGP+ C   + DGRI V+GG+D ++ V+  ++         
Sbjct: 3334 RYNTGDKIKVLEDHH----DGPLTCLTATEDGRICVSGGSDSLICVYNLKR--------F 3381

Query: 3473 XXXXXXCAHSQAVLCLAVSQPYSLIVSGSKDRTVIFWDLSSLEYVRQLPELPEPPTAIHA 3532
                    H+ ++ C++ S+PYS+IVSGS DRT I WDL+ L YVR L     P + I  
Sbjct: 3382 SLAKRLSGHTGSITCVSASRPYSIIVSGSDDRTCIIWDLNRLCYVRSLDAHEGPISCIGI 3441

Query: 3533 NDMTGEVVTAAGTTLSVWSINGDCLAAVNTSHVAADTILSITSPHLSDWMEASWYVTGHQ 3592
            +D TGE+V  +GTT+SV+++NG+ L    TS +A D I         +W+  +  +TGH+
Sbjct: 3442 HDTTGEIVVCSGTTISVYTVNGELLINYKTSQIANDQITCCIWSKGPEWLGENVLLTGHR 3501

Query: 3593 NGVIRLWHME---LDNHSKLDRRASHRISCSWGSNELSKSCVTGGPPEYQLVLYKVLS-- 3647
            +G +++W +E   L +++  +   ++  + +  + ++  +       +  ++L    S  
Sbjct: 3502 DGKVKVWGLETRLLPDNNNSNNNNNNNNNNNNNATQIPSTNNNKLKFKNVIILRATFSNS 3561

Query: 3648 -WHKEPVTALSLGNDLKQLCSGDAGGHLVSWT 3678
              H   +T++ L ND ++  +GD  G +  W+
Sbjct: 3562 QSHSTAITSIFLTNDQQKFYTGDITGRVCMWS 3593



 Score =  145 bits (367), Expect = 6e-33,   Method: Compositional matrix adjust.
 Identities = 184/872 (21%), Positives = 348/872 (39%), Gaps = 136/872 (15%)

Query: 767  ECLLSLLKKSDGNQTVFRKANGVGYILPLVASASQRSGALRVLSCLICEDINQAHADELK 826
            + L  L+ ++  N ++ R  +    +L  +  +S R  +LR+L  LI  D  +    E  
Sbjct: 730  DSLFILISENPDNISLIRSFSIFNILLRFLPYSSVRGKSLRILQQLIKYD-PEPTQKEFD 788

Query: 827  SLLKIAHXXXXXXXXXXXXXLDIEAKEDILWCVWRILGANSTTRVVFGDGNGFGLLLSVL 886
             L+K+                +   K DIL    ++   +   R  F +  GF  ++SV 
Sbjct: 789  GLIKVLTSVNKE---------NYPMKSDILNATRKLFNISKHARDSFREHGGFVSIISVF 839

Query: 887  EGIHSGCNDPSVESIGDEAAPASSLAVHMEVLDALLHVITVAAAESPTNRNKLHECVSSQ 946
              + S  +    +S   +          +E+++++    T A   +  NR    + +  +
Sbjct: 840  ISLESSFSPNRKDSRNWDME-------KLELIESICRCTTSALCGNVINRENFEQQIGYK 892

Query: 947  AFKRLLQRSGLLCPEFEQKVAERLFDVALERVHSPSQSNLGLPILSQGEGTKSFRIPGAE 1006
             F   L  +G+L  EF + V + +FD+  E +++  Q                       
Sbjct: 893  TFSSCLIMTGVLGTEFSKSVVDFIFDMVTENLNASDQI---------------------- 930

Query: 1007 GEFLVNPGQAAQMDVYNAGPIEVLLFFLPQFTVK-LQLRILVQVERFVNDSPWNQNALTS 1065
                     + QM + N     V+L  +P    K  +L+I+ ++ +      +NQ AL+ 
Sbjct: 931  ---------SNQMIINNVESFNVILDIIPHIENKDFRLQIISRINKMAEYGRYNQEALSK 981

Query: 1066 AGCVGHLLEVVKSMLQTKPSSLLSYALKIVEILGSFRLSASEMQTLGRIVWFNRDSSVGH 1125
                  +L    S L      L    L +++ +G+  LS SE++   +++         H
Sbjct: 982  LSIPDWILSRFPSNLSNANDPLQPLLLSLIQTVGANCLSGSELRQFVKLL------QPEH 1035

Query: 1126 MGQRLLQMVERMXXXXXXXXXXXXXXXXIEFRMSRMGHACLRTPLGDRTWPPTAGYSFVC 1185
              + LL+++  M                 EF +S++    +R P+ +R WPPT GY+ + 
Sbjct: 1036 SPEVLLKILSSMAKSPPTPPY-------FEFNLSKIPFGYIRVPITERAWPPTNGYTIMF 1088

Query: 1186 WARFEKL------SAQNGQNSSGAEASKELHRNRSGSLGSVLRILTVGTAEDKSSICAEL 1239
            W   +K       +  N  +++   ++   + N + +    + ++ + + + KSS+   L
Sbjct: 1089 WLYIDKFPTVNNNNNNNNSSNNSNNSNNSNNNNNNNNNNDQIDLVHIYSDDKKSSLYIYL 1148

Query: 1240 FLSDSGVLTLATSPTSYLCFK--GVRLEEGIWYHLTIVHNKPNALAGLFQSSVAYLYLNG 1297
                +G++T+    +S    +    +  EG WYH+ IVH +      L   +   L+++G
Sbjct: 1149 ---KNGIITVNIINSSKYVIEIPSYKFVEGKWYHIGIVHAR-----RLLGGTDFKLFVDG 1200

Query: 1298 SLRHTG-KLGYSASPV-GKPLQVTVGTSSSFSEVSPFTWQLGSCYLFEEVLPAPAIFFMY 1355
             L++T  K  Y A    G  L   +G S+     +   W++G+ YL E+ L A  I  +Y
Sbjct: 1201 FLKYTATKAQYPAQITSGSMLICDIGVSNQNRFPTDSIWRIGTFYLLEDSLGAKHINTIY 1260

Query: 1356 VLGRGYRGLFQDTDMLRFIP---YEACGGGNLMVLESLDT-ELLATLKAEGLSQNAGVAQ 1411
             LG  Y   F+     RF P   YE     NLM ++ LD  + L  L    +S      Q
Sbjct: 1261 FLGPNYASNFKG----RFSPYQTYEIVNSANLMAIKDLDYGDQLGPLNLAKVSM-----Q 1311

Query: 1412 LEGSGVIWDLEKLARFWAQLCGRHLIF--AYDGSHAEDVVPAGVMSMVNLVDPMSAAASV 1469
            ++ + ++  L    +         +++   ++G   E     GV   +N+    +  +  
Sbjct: 1312 IDENKILVGLCASNKLIRTNNSSKVVYNEIFNGIINELSQNHGV--ALNVFSSPNGTSPN 1369

Query: 1470 LGGLPRLAR-------------IHGDVHICTPCNIADTMRKV------------------ 1498
            L GL                  + G V I    ++   +R V                  
Sbjct: 1370 LTGLQNNNNNNNNSGGSNSKKDLEGRVEIINQADLTTKLRGVLIGSVEAFRRNKVADSIK 1429

Query: 1499 --GGVAVVLAMIEAADSCETLHLALSVLVSMLQSNPRNARDMQACRGYHLLALFLHRR-- 1554
              GG+ + L ++E A+S ETL  +L +LV ++Q +P N  +M    GY LLA  L ++  
Sbjct: 1430 KIGGMPISLLLLEKANSEETLFDSLGLLVGLIQYHPTNTHEMSQINGYELLAWVLKKKAS 1489

Query: 1555 MDYFEARDLDFLFRI----ASCEASFVQKPPQ 1582
            +  F +  L+ LF +     +C  +   + PQ
Sbjct: 1490 LGLFNSNILELLFDLIGINGNCSTTITSRAPQ 1521



 Score = 85.9 bits (211), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 96/480 (20%), Positives = 192/480 (40%), Gaps = 102/480 (21%)

Query: 2244 ILDFIAEVLAETLLEQAKSITVVESILEAVPMYVNSDAALIFQGLVLRRIINDLERRLMR 2303
            ++ F+ +++   + + +K+I+++E +LE  P     +  +++   +L  ++  +E  + +
Sbjct: 2129 VVKFLCQIMLSAMRKTSKAISIIEMVLEGAPTTATDEEFILYHSRILLDLMYVVETNITK 2188

Query: 2304 DSEENHKKLDKNRWAPNLDTLSWLLVDRVYMGAFAEAGGPL---NVLEYLLSMLQLANAD 2360
                  +  D  R   NL  LS +LVDRV +    +    +    +  +++ +L+   AD
Sbjct: 2189 T-----EFFDNERVHSNLIKLSSMLVDRVNLDQLVKNNKIIIAKRIFLFIVKILEKLEAD 2243

Query: 2361 GRVEDATPTAKGMLFTRSGGRQAESYVQSLLKNTNRMLMFCFLPQLINSPVEEDFPATNG 2420
                            R G ++    VQSL K+ NR++++     LIN   + D      
Sbjct: 2244 ----------------RVGLQKT---VQSLYKSLNRIILY-----LINHTTDTDL----- 2274

Query: 2421 KKINPSASGSEIVMESVPKCLERVSGDVGVTYQVILDKAAVLQLLLANRKIIFCTINVDL 2480
                                                  + V   ++ +++IIF   N+D 
Sbjct: 2275 --------------------------------------SFVANHIINHQRIIFSENNLDS 2296

Query: 2481 ELVCALCINLFPMALDTEQSNKTVVFEVWKALLTHRSSA----LEDVLITRGSQGSV--- 2533
            + + A C  L+ + +  +  +     ++W+ LL+ ++S+    L  VL  + S GS    
Sbjct: 2297 DFMNAFCYPLYKLVISDQHEHVDNSIKLWRLLLSLKTSSYIESLATVLQLKVSSGSNQRQ 2356

Query: 2534 --LMDVLHGGFDRLLKA------GVQDFFVWLQENWESVQRVLEQRASTIWRDYVSAASR 2585
              ++D L  GF+ L            +F +W+ +N +++ +V E+        + +   +
Sbjct: 2357 SEIID-LKPGFELLRNTSGNGAFNNDEFKLWINDNIQTITQVFEENPKKQHLSFKNNEKK 2415

Query: 2586 FPAARTKXXXXXXXXXXXXXXXXXXKMDTRHWEQMLER--RVALELVREA--MAAELRVL 2641
              +  T                   + D  H E+  +   + A   VR       +++ L
Sbjct: 2416 HSSEHTLPSLKSRRTERLSKKQRQDRKDQSHQEEKSKHITKKAQYFVRSESDRRKKIKQL 2475

Query: 2642 RQDKYGWILHAENGWADHLQQLVHERGIW-PIVPEVCDEEPDWQLCPTEGPYRMRKKLER 2700
              DK  +       W +   Q+  ER +W P  P   D+   W+L  TEGPYRMRKK+E+
Sbjct: 2476 ESDKQKF---NAIQWENMRAQITRERAVWGPSEPHPLDK---WKLDSTEGPYRMRKKMEK 2529



 Score = 54.3 bits (129), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/95 (28%), Positives = 54/95 (56%)

Query: 624 FASHPDNYVLVQERRTMPLFLQNMGSYALILQERLLKVLEYAVTVVNCIPEQELLSLCYL 683
           ++S+  N++L+Q   T+  F+Q   S +  L+  ++K++ + VTV+NC+P QEL +   L
Sbjct: 530 YSSNTVNFILLQHTSTLTKFIQEYESLSNGLKYHVMKIVCFVVTVLNCVPFQELSTFSLL 589

Query: 684 LQQPYASPLRKTVLSFFGKLLSFDRNYKKVLREVG 718
           + +  +    + +      L++F+  YK + RE G
Sbjct: 590 VGENPSFYTLEMINQLITTLVNFEFRYKHIFRETG 624

 Score =  501 bits (1290), Expect = e-141,   Method: Compositional matrix adjust.
 Identities = 325/940 (34%), Positives = 480/940 (51%), Gaps = 117/940 (12%)

Query: 2864 LERGERIRFRYNCERVVGLDKRDGIFLIGEKCLYVIENYIIDENKCIKEKGEERDLSIID 2923
            +E G+ I+  YN  R+ GL+  +GI L+G++ LY+++N+ +  +    E  +  D SIID
Sbjct: 1734 IESGDSIQDVYNVSRIFGLEATEGILLLGKQYLYLMDNFFLRSDN---EIVDVNDNSIID 1790

Query: 2924 Q-------ALGVRANSTGVVDMNISKQTEVAADSWAGGRAWAYSGGAWGKEKVKAGQNMP 2976
            +             +S+G V  +ISK+     ++W                         
Sbjct: 1791 ERDPYLQLLHLQSLSSSGKVRRHISKE-----NNWH------------------------ 1821

Query: 2977 HPWRMWKLESVHELLKRRYQLRPVAIELFSMDGCNDLLVF-HKNERDEVFKTLLA----M 3031
                 W    +  +LKR Y LR V +ELF  DG + L +  +   RD +++ L+A     
Sbjct: 1822 -----WDFIDLSLVLKRFYLLRDVGLELFFKDGRSFLTILSNTKNRDSLYQKLVARAPGA 1876

Query: 3032 NLPRNSMLDTTISAASKQEAGEGGRLFKMMAKSFS--------KRWQNGEISNFQYLMHL 3083
            ++   S   T++S    +  G+   L   +A + S        KRW+  EISNF YL  +
Sbjct: 1877 DVLSTSHFATSMSRDLGKANGKSNFLSSKLANALSFSTTHPATKRWERREISNFNYLQIV 1936

Query: 3084 NTLAGRGYNDLTQYPVFPWILKDYTSEELDLSNPDTFRRLDKPMGALHPEREKEFRKRYE 3143
            NTLAGR YNDLTQYPVFPW++ DYTS+ELDL+NP T+R   KPMGA HPERE +F +RY+
Sbjct: 1937 NTLAGRTYNDLTQYPVFPWVIADYTSKELDLNNPKTYRNFCKPMGAQHPERESQFNERYD 1996

Query: 3144 TW---EDPEIPRFHYGSHYSSAGSVLFYLIRLPPFSQENKQLQGGAFDHADRLFNSIKDT 3200
                  D +   FHYG+HYSSA  V  YLIRL PF      LQGG FDHADRLF SI+  
Sbjct: 1997 LLLGLNDSQQQPFHYGTHYSSAMIVCSYLIRLRPFVDSYLALQGGQFDHADRLFYSIEQA 2056

Query: 3201 YLSASQGNTADVKELIPEFFYLPEFLENRFGFDFGVKQS-GERVNDVLLPPWAKGSAREF 3259
            + S+S+ N ADV+ELIPEFFYL E   N  GFDFG +Q     +NDV+LPPWAKG    F
Sbjct: 2057 WRSSSKENMADVRELIPEFFYLSEMFINGNGFDFGSRQKESTPINDVILPPWAKGDPAIF 2116

Query: 3260 VRKHREALESQYVSENLHHWIDLIFGFKQRGKPAVEALNVFYHLTYEGAVDIDRVPDPAM 3319
            V+K+REALES+YVS +LH WIDL+FG KQRG  AV A NVF+HL+Y+GA+D++ + +   
Sbjct: 2117 VQKNREALESKYVSAHLHEWIDLVFGCKQRGDEAVAATNVFHHLSYQGAIDLENIENEFE 2176

Query: 3320 KAAVLAQINHFGQTPKLLFTKPHPKR-KWVQKQPLALAL-----RNYHLLAPQEMRPLSS 3373
             AA +  I++FGQTPK +F KPHP+R       PL   L      + HLL  Q   P+  
Sbjct: 2177 LAAAVGIIHNFGQTPKQVFKKPHPQRGPDFTDTPLGPYLFGRFEDSIHLLF-QSCSPIIR 2235

Query: 3374 RVSQIVIFQ-----DKVYAAGANRI-LKPPSFTKYLCWGFSDRSLRIISYEQERLLSTHE 3427
               ++   Q     D+V A  A+   L P +F   L WG  D ++++IS + ++     E
Sbjct: 2236 ICKKVAHIQYDPSKDEVGAFAADYTPLGPNTF---LAWGRVDNTVQLISDQLDKQPVMFE 2292

Query: 3428 NLHDDG---PVLCTGFSRDGRILVTGGADGVVSVWRQRKDXXXXXXXXXXXXXXCAHSQA 3484
             LH +     V C     D R  +T   D  + +W    +                H   
Sbjct: 2293 ELHSEKITHVVAC-----DERTFLTASLDLTLRLWTLSTNKPIKASLKRVLY---GHRYR 2344

Query: 3485 VLCLAVSQPYSLIVSGSKDRTVIFWDLSSLEYVRQLPELPEPPTAIHANDMTGEVVTAAG 3544
            + C+ V + +S+IVSG     +I WDL+  E+V  L     P   I  N    E+  + G
Sbjct: 2345 ITCVTVCKAFSIIVSGDAGGNLIIWDLNRAEFVSSLSVYKLPIQTIAVNARNAEIAFSTG 2404

Query: 3545 TTLSVWSINGDCLAAVNTSHV----AADTIL--SITSPHLSDWMEASWYVTGHQNGVIRL 3598
                V ++NG  L     S +    + + IL     +   S+W+  + ++TGH +G+IR+
Sbjct: 2405 FYCCVVNVNGKILVKDKLSRIYNENSDENILCSCFYTGANSEWLHKNLFITGHPDGIIRI 2464

Query: 3599 WHMELDNHSKLDRRASHRISCSWGSNELSKSCVTGGPPEYQLVLYKVLSWHKEPVTALSL 3658
            W   L +++KL+   ++     W  + L +   T G    ++         ++ +  ++ 
Sbjct: 2465 WEKRLQSNAKLEAEKNNADRPKWRFHLLRQLQHTKGLGRNRVAT-------RQNIITITP 2517

Query: 3659 GNDLKQLCSGDAGGHLVSWTLPDDGFKQTPSLEIEPDQ----CTTCQKELNLTEMKHHCR 3714
                + + +GD  G + SW LPD     T ++ +E D     C+ C    +L E +  CR
Sbjct: 2518 NGQARGIFAGDDKGQVFSWMLPD----TTSNVHLEKDNTSELCSLCDSRFSLMEWRSQCR 2573

Query: 3715 NCGQIS-CADCCNNHIVLEDLGYFSPVRVCGSCYESRQSC 3753
             CG  + C+DC +   +L+D    + ++ C  CY     C
Sbjct: 2574 ACGNSNVCSDCVS---MLKD----TNIKTCYECYRQMPLC 2606

 Score =  475 bits (1223), Expect = e-133,   Method: Compositional matrix adjust.
 Identities = 275/735 (37%), Positives = 392/735 (53%), Gaps = 64/735 (8%)

Query: 2987 VHELLKRRYQLRPVAIELFSMDGCNDLLVFHKNERDEVFKTLLAMNLPRNSMLDTTISAA 3046
            + EL + R+ L+ +A+E+F  +G +  LVF+ N+R + FK+  +           ++   
Sbjct: 2468 MRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQ--------PSLKGK 2519

Query: 3047 SKQEAGEGGRLFKMMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYNDLTQYPVFPWILKD 3106
            +  E     R +    +   ++WQ  +ISNF+YLM+LNT AGR  ND  QYPVFPW+L D
Sbjct: 2520 ATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLAD 2579

Query: 3107 YTSEELDLSNPDTFRRLDKPMGALHPEREKEFRKRYETWEDPE---IPRFHYGSHYSSAG 3163
            YTSE L+L+NP  FR L KPMGA   ER+ +F +R++  E  E     + HY +HYSSA 
Sbjct: 2580 YTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAI 2639

Query: 3164 SVLFYLIRLPPFSQENKQLQGGAFDHADRLFNSIKDTYLSASQGNTADVKELIPEFFYLP 3223
             V  YL+R+PPF+Q    LQGG+FD ADR+F+S+K T+ SAS+ N +DV+EL PEFFYLP
Sbjct: 2640 IVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESASRENMSDVRELTPEFFYLP 2699

Query: 3224 EFLENRFGFDFGVKQSGERVNDVLLPPWAKGSAREFVRKHREALESQYVSENLHHWIDLI 3283
            EFL N  G +FG  Q G  + DV LPPWA G  R+F+  HR+ALES +VS NLHHWIDLI
Sbjct: 2700 EFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLI 2759

Query: 3284 FGFKQRGKPAVEALNVFYHLTYEGAVDIDRVPDPAMKAAVLAQINHFGQTPKLLFTKPHP 3343
            FG+KQ+G  AV+A+N+F+   Y   +D+  + DP +K+ +L  +++FGQ PK LFTKPHP
Sbjct: 2760 FGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHP 2819

Query: 3344 KRKWVQK---------------------------QPLALALRNYHLLAPQEMRPLSSRVS 3376
             R    K                           +P  + +++ +L +     P  + + 
Sbjct: 2820 ARTAAGKPLPGKDVSTPVSLPGHPQPFFYSLQSLRPSQVTVKDMYLFSLGSESPKGA-IG 2878

Query: 3377 QIVIFQDKVYAAGANRILKPPSFTKYLCWGFSDRSLRIISYEQERLLSTHENLHDDGPVL 3436
             IV  +  + A   N++L PP + +   WGF D S  + SY  +++L T ENL   G  L
Sbjct: 2879 HIVSTEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGRCL 2938

Query: 3437 CTGFSRDGRILVTGGADGVVSVWRQRKDXXXXXXXXXXXXXXCAHSQAVLCLAVSQPYSL 3496
            C         +VT G   VV VW +                   H+QAV CLA S  +SL
Sbjct: 2939 C-AVCPSPTTIVTSGTSTVVCVW-ELSMTKGRPRGLRLRQALYGHTQAVTCLAASVTFSL 2996

Query: 3497 IVSGSKDRTVIFWDLSSLEYVRQLPELPEPPTAIHANDMTGEVVTAAGTTLSVWSINGDC 3556
            +VSGS+D T I WDL  L +V +LP   E  +AI  +D++G +V+ AG  LS+W++NG  
Sbjct: 2997 LVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNGQP 3056

Query: 3557 LAAVNTSHVAADTILSITSPHLSDWMEASWYVTGHQNGVIRLWHMELDNHSKLDRRASHR 3616
            LA++ T+      I          W  +   +TG Q+G++R+W  E    S   R A   
Sbjct: 3057 LASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSVPGRPAGEE 3116

Query: 3617 ISC--------SWGSN-----ELSKSCVTGGPPEYQLVLYKVLSWHKEPVTALSLGNDLK 3663
                        W  N     EL  S    G P          S     VTAL++  +  
Sbjct: 3117 PPAQPPSPRGHKWEKNLALSRELDVSIALTGKP----------SKTSPAVTALAVSRNHT 3166

Query: 3664 QLCSGDAGGHLVSWT 3678
            +L  GD  G +  W+
Sbjct: 3167 KLLVGDERGRIFCWS 3181



 Score = 63.2 bits (152), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 101/471 (21%), Positives = 173/471 (36%), Gaps = 103/471 (21%)

Query: 1154 IEFRMSRMGHACLRTPL--------------------GDRTWPPTAGYSFVCWARFEKLS 1193
            +EF MS  G+ CL  P                       R +PP  G +F CW       
Sbjct: 1023 VEFDMSVEGYGCLFIPTLSTVMGTSTEYSVSGGIGTGATRPFPPPGGLTFSCWFL----- 1077

Query: 1194 AQNGQNSSGAEASKELHRNRSGSLGSVLRILTVG---TAEDKSSICAELFLS-DSGVLTL 1249
                           + R+ + + G  LR LT+       ++  +C  + L  D   L +
Sbjct: 1078 ---------------ISRHGAATEGHPLRFLTLVRHLARTEQPFVCFSVSLCPDDLSLVV 1122

Query: 1250 AT----------------SPTSYLCFKGVR----LEEGIWYHLTIVHNKPNALAGLFQSS 1289
            +T                S  S  C   VR    L  G W+HL +V  K      + +  
Sbjct: 1123 STEEKEFQPLDVMEPEDDSEPSAGCQLQVRCGQLLACGQWHHLAVVVTKE-----MKRHC 1177

Query: 1290 VAYLYLNGSLRHTGKLGYSASPVGKPLQVT----------VGTSSSFSEVSPFTWQLGSC 1339
                 L+G +  + K+ Y  +  G  L +           + T   + + S   W+LG  
Sbjct: 1178 TVSTCLDGQVIGSAKMLYIQALPGPFLSMDPSAFVDVYGYIATPRVWKQKSSLIWRLGPT 1237

Query: 1340 YLFEEVLPAPAIFFMYVLGRGYRGLFQDTDMLRFIPYEACGGGNLMVLESLDTELLATLK 1399
            YLFEE +    +  +  LG  Y G FQ   +                 E LD+E    + 
Sbjct: 1238 YLFEEAISMETLEVINKLGPRYCGNFQAVHVQG---------------EDLDSEATPFVA 1282

Query: 1400 AEGLSQNAGVAQLEGSGVIWDLEKLARFWAQLCGRHLIFAYDGSHAEDVVPAGVMSMVNL 1459
             E +S    +A    S  I  +  +   + ++  R +    + S  ++ +P  V  + N 
Sbjct: 1283 EERVSFGLHIA----SSSITSVADIRNAYNEVDSRLIAKEMNISSRDNAMP--VFLLRNC 1336

Query: 1460 VDPMSAAASVLGGLPRLARIHGDVHICTPCNIADTMRKVGGVAVVLAMIEAADSCETLHL 1519
               +S +   +G +  + ++   V   +P   A ++  +GG A++L +I  A    T++ 
Sbjct: 1337 AGHLSGSLRTIGAV-AVGQLGVRVFHSSPA--ASSLDFIGGPAILLGLISLATDDHTMYA 1393

Query: 1520 ALSVLVSMLQSNPRNARDMQACRGYHLLALFLHRRMDYFEARDLDFLFRIA 1570
            A+ VL S+L SN      MQ   GY ++A  L ++      R    +  +A
Sbjct: 1394 AVKVLHSVLTSNAMCDFLMQHICGYQIMAFLLRKKASLLNHRIFQLILSVA 1444