Score =  644 bits (1662), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 443/1384 (32%), Positives = 672/1384 (48%), Gaps = 205/1384 (14%)

Query: 1905 KATPLVEATLEAVPLHIGGDIAVVFQGLCLYRVMNFLERRLQRDDEEAHKKLDRAR---- 1960
            K TPL++  LEA P          FQ   L  VM+ L        E+A   +        
Sbjct: 1981 KQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQV 2040

Query: 1961 WSSNLDAFSSLVVDRVYMGAFSDSAGVLKVLEFLLSMLQLANKHGRVEEAMTTGRSLLSL 2020
              +N+  F+  VVD+++ G F+  + +L  ++F++ ++  + +  +       G SL   
Sbjct: 2041 LVNNVFYFTQRVVDKLWQGMFNKESKLL--IDFIIQLIAQSKRRSQ-------GLSL--- 2088

Query: 2021 ARGGFKQLEPFVQSLLRNTNRMLLFCFLPSPTTNEELTSSNTGLLAKGGLDITLVLQLLI 2080
                         ++    NR +L+ F    +   +       LL          L++L 
Sbjct: 2089 ------------DAVYHCLNRTILYQF----SRAHKTVPQQVALLDS--------LRVLT 2124

Query: 2081 SHKKLVLCPGNVDSEFLQCL---LVNI-----------------------VPLLQDPRQA 2114
             ++ L+L PGN D EF+ CL   L+N+                       +P   +P  +
Sbjct: 2125 VNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGS 2184

Query: 2115 V-------RTLAVDACK----VLLHYRKEALEDILVLRHASGEALDVFHGGFDKLLASNS 2163
                    R L + A       L+H +K+ LE++  +     E   V       L+   +
Sbjct: 2185 YSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAA 2244

Query: 2164 IGFYTWFDD-AHD--------AIGRVLEQRASLAWMQFIGGAARFNSSRLKNFEVRRKRE 2214
            +    W +  AH+        A+    + + S     F  G ++   SR      R ++E
Sbjct: 2245 LK--CWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGF--GLSKLTGSR------RNRKE 2294

Query: 2215 MGRRMKDASKADGRHWEQMLERRVALDMVRDSLSAELRLMRQVKYGWVIHAENEWQDHIQ 2274
             G      S  +   W         + +VRD +  + +  ++ +   + +   EW     
Sbjct: 2295 SGLNKHSLSTQEISQW-----MFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIEC 2349

Query: 2275 QLMHERGLWPVVKPVAESDNEWQLCSTEGPYRMRKKLVRCKPKID----IXXXXXXXXXX 2330
            +L+ ERGLW    P+    ++W L  TEGP RMRKK+VR     +    +          
Sbjct: 2350 ELLRERGLWG--PPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVA 2407

Query: 2331 XVLPNGQAGFAVDIENP---------DYDSFFHIFSLGIDSPKKNAAKDYLESFDEEDTE 2381
              +P+ Q     DI             YDS  +   L   +P        +ES + E  +
Sbjct: 2408 SEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAI-VQDAIVESSEGEAAQ 2466

Query: 2382 SKGREDDANSLSTRG--DGTIERSRSAINDSGKSPESIQRSKSDAHGTAPGSSPTKXXXX 2439
             +    +      +G     ++RSRSA  D G      Q     A G++           
Sbjct: 2467 QEPEHGEDTIAKVKGLVKPPLKRSRSA-PDGGDEENQEQLQDQIAEGSS----------- 2514

Query: 2440 XXXXXXXXXXXXXXEYLIAPYLERGEKIRFRYNCERVAGLDKHDGIFLIGERCLYIIENY 2499
                             +   LE GEKI+  Y C RV GLD  +G+ L G+   Y+I+  
Sbjct: 2515 ------IEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDG- 2567

Query: 2500 FIDSAGRICEKGGEGELSVIDQALGVKTSISVVFESTQTATWSDTENTWPGGKAWACSGG 2559
                                             F  T T    D E   P         G
Sbjct: 2568 ---------------------------------FTMTATREIRDIETLPPNMHEPIIPRG 2594

Query: 2560 AWGKEKLSSGRQMPHSWRMWKLDSVHELLKRWYQLRPVAIELFSMDGCNDLLVFHKEERD 2619
            A          Q+  +  ++  + + E+ KR Y L+P+A+E+FS DG N LL F K  R+
Sbjct: 2595 A-----RQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRN 2649

Query: 2620 EVFKNLLSINLPRSSRLETAISGVSKLDSNEGGR-LFKTMA--KSFSKRWQNGEISNFQY 2676
            +V++  L++ +P  +    ++SG     S E G  L  T+   KS ++RW+ GEISNFQY
Sbjct: 2650 KVYQRFLAV-VPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQY 2708

Query: 2677 LMHLNTLAGRGYNDLTQYPVFPWVLADYESEELNLSNPTVYRRLDKPMGALSLEREDVFR 2736
            LMHLNTLAGR YNDL QYPVFPW+LADY+SEE++L+NP  +R L KPMGA + ER   ++
Sbjct: 2709 LMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYK 2768

Query: 2737 KRYDNWDDP--EIPKFHYGSHYSSAGTVLFYLIRLPPFSQENLKLQGGQFDHADRLFTNI 2794
            KRY +W+DP  E P +HYG+HYSSA  V  YL+R+ PF+Q  L+LQGG FD ADR+F ++
Sbjct: 2769 KRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSV 2828

Query: 2795 RDTWLSASQGNTADVKELVPEFFYLPEFLENKFDLDLGTKQSGEKVDDVVLPPWAKGSAR 2854
            R+ W SAS+ N ADVKEL+PEFFYLPEFL N  + DLG KQ+G K+ DV+LPPWAKG  R
Sbjct: 2829 REAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPR 2888

Query: 2855 EFIRKHREALESQYVSENLHHWIDLIFGYRQRGQAAVDATNVFYYLTYEGAVDIDSVRDP 2914
            EFIR HREALE  YVS +LH WIDLIFGY+Q+G AAV+A NVF++L YEG VDI ++ DP
Sbjct: 2889 EFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDP 2948

Query: 2915 ALKASTLAQINHFGQTPRQLFLKPHPGRKCQQ------------------KVPFGHVLRS 2956
              + +T+  IN+FGQ P+QLF KPHP ++ +                   K+ F H+   
Sbjct: 2949 LKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNL 3008

Query: 2957 SQLLAPQEIRNATTSIAQIVVSHDKVFSVGHNRLLKPRSYSKYIAWGFPDNSLRFVSYDQ 3016
               L P  ++     + QIV +   + +V  N++L P +++K  AWG+ D S R  +Y+ 
Sbjct: 3009 RPSLTP--VKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYES 3066

Query: 3017 DRLLSTHEGLHD-GTIVCAGFSRDGRTLVTGGEDGVASVWRLRKDGVRNQRRLHLQRALC 3075
            D+ ++ +E L + G I+CA    + + ++TGG   V  VW +     +  + + L++AL 
Sbjct: 3067 DKAMTVYECLSEWGQILCA-ICPNPKLVITGGTSTVVCVWEMGTSKEK-AKTVTLKQALL 3124

Query: 3076 AHSDSVTCLSVCQPYNLVVTGSSDCTVIFWDLSTLEFVRQLPQLPAPASAVHTNEMTGEI 3135
             H+D+VTC +    Y+++V+GS D T I WDL+ L F+ QL    AP SA+  NE+TG+I
Sbjct: 3125 GHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDI 3184

Query: 3136 VTAAGTMLVVWSVNGDCLAALNVSRLASEAIVSITSPVLSDWMETGWYVTGHQNGAIKLW 3195
            V+ AGT + VWS+NG+ + ++N     S+ I+      +++W      VTGH +G ++ W
Sbjct: 3185 VSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFW 3244

Query: 3196 RIDY 3199
            R+++
Sbjct: 3245 RMEF 3248



 Score = 80.5 bits (197), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 94/416 (22%), Positives = 149/416 (35%), Gaps = 52/416 (12%)

Query: 826  ISLGDRSWPPAAGYSFMCWLRFTGIEGKTKGGRSRPALRIFMVESVEEKGTVLAELYLND 885
            I  G+R +PP +G S+  W               R    +    S E+    LA +    
Sbjct: 1087 IGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAK 1146

Query: 886  SGLLTLATGPSSLLAFK---------------------GVRLEEGLWYHIVIVHNKPNAL 924
               L ++T    L  +                      G  + EG W+H+V+V +K    
Sbjct: 1147 DRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSK---- 1202

Query: 925  AGLFQSSVASLYVNGNLRHTGKLGYSPSSFG----------KTIQAVIGIPPQLSDVSSS 974
             G+ ++S A+LY++G L +T KL Y  S+ G           T+ A IG PP    ++S 
Sbjct: 1203 -GMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASL 1261

Query: 975  TWQMTGCYLFEEVLPSQAVCLVYALGRGYRGLFQDTDLLRFVPYEACGGGNLAVLEGLET 1034
             W++   +  EEVLPS  V  +Y LG  Y G FQ            C     A  EG+  
Sbjct: 1262 VWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQ----------AVCMPCKDAKSEGVVP 1311

Query: 1035 ASAGVNVQKGGDAAKYRIDGSGAVWELERLVSFWIQLSNKKLIFSFDXXXXXXXXXXXXS 1094
            +   +  ++      Y +  S     + R+   + +L +K +                  
Sbjct: 1312 SPVSLVPEEKVSFGLYALSVSSLT--VARIRKVYNKLDSKAIAKQLGISSHENATPVKL- 1368

Query: 1095 IVNLVEPLSAAASPLGGLPRIGRLVGDVEILNPCSFGDSMRKVGGMXXXXXXXXXXXTGE 1154
            I N    L+ +A  +G    IG L   V    P     +++ VGG              E
Sbjct: 1369 IHNSAGHLNGSARTIGA-ALIGYL--GVRTFVPKPVATTLQYVGGAAAILGLVAMASDVE 1425

Query: 1155 MXXXXXXXXXXXXYYNPRNTYDMLACRGYHLLVLFLHRRIRLFEVQDLELLFQIAA 1210
                           NP  + +M   +GY LL + L ++  L     L L F +  
Sbjct: 1426 GLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVG 1481



 Score = 59.7 bits (143), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 9/111 (8%)

Query: 3229 HLVLHKVLKSHTQPVTALHLSPDLKQLYSGDAGGHVTSWVLSTLDGSSVQP--------E 3280
            H    +   +H   VTAL +S D  ++  GD+ G V SW +S   G S           +
Sbjct: 3399 HTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGD 3458

Query: 3281 TCPWCQDVLDVAQLKRYCRNCGKFSCQRCGE-SAPVVELGYVDPVPICWSC 3330
            +C  C     + + + +CRNCG+  CQ+C    + +  L    PV +C +C
Sbjct: 3459 SCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNC 3509

 Score =  633 bits (1632), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 337/840 (40%), Positives = 485/840 (57%), Gaps = 106/840 (12%)

Query: 2471 YNCERVAGLDKHDGIFLIGERCLYIIENYFIDSAGRICEKGGEGELSVIDQALGVKTSIS 2530
            YNC  V G+DK +GI +     +YI + Y+ D           G++S +++ +       
Sbjct: 2816 YNCGSVDGMDKIEGILIFCPVYMYIFDGYYKDE--------NTGDISEVEEKIN------ 2861

Query: 2531 VVFESTQTATWSDTENTWPGGKAWACSGGAWGKEKLSSGRQMPHSWRMWKLDSVHELLKR 2590
                                   W   G       L   +++ H +  W  + + ++LKR
Sbjct: 2862 ---------------------SEWLPEGTV-----LPMKKKIIHYFLKWAYEDIRDVLKR 2895

Query: 2591 WYQLRPVAIELFSMDGCNDLLVFHKE-ERDEVFKNLLSINLPRSSRLETAISGVSKLDSN 2649
             Y LR VA+E+FS DG N+L+V+  E  RDEV+  L++ N+   + +     G++     
Sbjct: 2896 RYLLRQVALEIFSTDGRNNLVVYRDEPTRDEVYHTLVN-NVSSHNTIGGDAQGIT----- 2949

Query: 2650 EGGR--------------------LFKTMAKS--FSKRWQNGEISNFQYLMHLNTLAGRG 2687
             GG+                     F ++ +    + +WQ G+ISNFQYLMHLNTLAGR 
Sbjct: 2950 -GGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLKWQQGQISNFQYLMHLNTLAGRS 3008

Query: 2688 YNDLTQYPVFPWVLADYESEELNLSNPTVYRRLDKPMGALSLEREDVFRKRYDNWDDPE- 2746
            YNDLTQYPVFPWVL+DYESEEL++ +P VYR L KPMGAL   R   FR+R++NWDD E 
Sbjct: 3009 YNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPMGALEESRAQKFRERFENWDDQEP 3068

Query: 2747 ------IPKFHYGSHYSSAGTVLFYLIRLPPFSQENLKLQGGQFDHADRLFTNIRDTWLS 2800
                  +PKFHYG+HYSSA  VL+YLIRL PF+Q  LKLQGG++D  DRLF++I + W S
Sbjct: 3069 NEHGHKVPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQPDRLFSSITEAWAS 3128

Query: 2801 ASQGNTADVKELVPEFFYLPEFLENKFDLDLGTKQSGEKVDDVVLPPWAKGSAREFIRKH 2860
            +SQG+T  V EL+PEF+YL EFL N    + GTKQ GE +DD++LPPWAKGS +EFI+ H
Sbjct: 3129 SSQGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIILPPWAKGSPQEFIKLH 3188

Query: 2861 REALESQYVSENLHHWIDLIFGYRQRGQAAVDATNVFYYLTYEGAVDIDSVRDPALKAST 2920
            R+ALES YVSE+LH WIDLIFGYRQ+G+AA D+ NVFYYLTYEGAV+ID++ DP  KA+T
Sbjct: 3189 RKALESDYVSEHLHEWIDLIFGYRQQGKAADDSLNVFYYLTYEGAVNIDAISDPVEKAAT 3248

Query: 2921 LAQINHFGQTPRQLFLKPHPGRKCQ-QKVPFGHVLRSSQLLAPQEIRNATTSIAQIVVSH 2979
            +AQIN+FGQTP+QLF KPHP R      +PF      ++ L    I++    + QI + +
Sbjct: 3249 IAQINNFGQTPKQLFDKPHPKRNATLMGLPF-----YAKALTGNFIKDIGEPVGQIRLIN 3303

Query: 2980 DKVFSVGHNRLLKPRSYSKYIAWGFPDNSLRFVSYDQDRLLSTHEGLHDGTIVCAGFSRD 3039
            D+   VG N++L P ++SKY+ WG PD S+R+ + D+ ++L  H   HDG + C   + D
Sbjct: 3304 DRATCVGFNKVLLPPNHSKYMLWGLPDGSIRYNTGDKIKVLEDH---HDGPLTCLTATED 3360

Query: 3040 GRTLVTGGEDGVASVWRLRKDGVRNQRRLHLQRALCAHSDSVTCLSVCQPYNLVVTGSSD 3099
            GR  V+GG D +  V+ L        +R  L + L  H+ S+TC+S  +PY+++V+GS D
Sbjct: 3361 GRICVSGGSDSLICVYNL--------KRFSLAKRLSGHTGSITCVSASRPYSIIVSGSDD 3412

Query: 3100 CTVIFWDLSTLEFVRQLPQLPAPASAVHTNEMTGEIVTAAGTMLVVWSVNGDCLAALNVS 3159
             T I WDL+ L +VR L     P S +  ++ TGEIV  +GT + V++VNG+ L     S
Sbjct: 3413 RTCIIWDLNRLCYVRSLDAHEGPISCIGIHDTTGEIVVCSGTTISVYTVNGELLINYKTS 3472

Query: 3160 RLASEAIVSITSPVLSDWMETGWYVTGHQNGAIKLWRIDYASFAQXXXXXXXXXXXXXNV 3219
            ++A++ I         +W+     +TGH++G +K+W ++                   N 
Sbjct: 3473 QIANDQITCCIWSKGPEWLGENVLLTGHRDGKVKVWGLETRLLPDNNNSNNNNNNNNNNN 3532

Query: 3220 CFTGGTPEYH---------LVLHKVL---KSHTQPVTALHLSPDLKQLYSGDAGGHVTSW 3267
                  P  +         ++L       +SH+  +T++ L+ D ++ Y+GD  G V  W
Sbjct: 3533 NNATQIPSTNNNKLKFKNVIILRATFSNSQSHSTAITSIFLTNDQQKFYTGDITGRVCMW 3592



 Score =  104 bits (260), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 173/835 (20%), Positives = 313/835 (37%), Gaps = 148/835 (17%)

Query: 462  DCLLSLLKRNEANQTAFRKAHGFDALQPLLLSDIHRTYVLRVLSCLISEDTVQSHPEELK 521
            D L  L+  N  N +  R    F+ L   L     R   LR+L  LI  D   +  +E  
Sbjct: 730  DSLFILISENPDNISLIRSFSIFNILLRFLPYSSVRGKSLRILQQLIKYDPEPTQ-KEFD 788

Query: 522  ALLGTTRAGQGQGISFKAKTDILWAVFRILCSNPAAKDVFGEGKGFTLMHTVLESLED-F 580
             L+    +   +  ++  K+DIL A  ++   +  A+D F E  GF  + +V  SLE  F
Sbjct: 789  GLIKVLTSVNKE--NYPMKSDILNATRKLFNISKHARDSFREHGGFVSIISVFISLESSF 846

Query: 581  SGAEPRQR------MEIVNALLHVVTVGVAGHSVNRIRLNDCVLSHAFSAALLKTGLICG 634
            S      R      +E++ ++    T  + G+ +NR      +    FS+ L+ TG++  
Sbjct: 847  SPNRKDSRNWDMEKLELIESICRCTTSALCGNVINRENFEQQIGYKTFSSCLIMTGVLGT 906

Query: 635  DYEXXXXXXXXXXCLEKVQSPARNVDSFRAGTWDNEFISVDERRELFNAGLVQVALQLFD 694
            ++             E + +         +    N+ I      E FN  L  +      
Sbjct: 907  EFSKSVVDFIFDMVTENLNA---------SDQISNQMII--NNVESFNVILDIIPHIENK 955

Query: 695  DFSPKAQLKVVTSVEALSEGSLVNKDRLTLAGCLKMVLEILTPSASYS-----PAIWMHG 749
            DF    +L++++ +  ++E    N++ L+       +L     + S +     P +    
Sbjct: 956  DF----RLQIISRINKMAEYGRYNQEALSKLSIPDWILSRFPSNLSNANDPLQPLL---- 1007

Query: 750  MQIVKLLGSYRISSFELRALLRYMWQCRDYTYGQVAQRYIEALEGVVHXXXXXXXXXXXX 809
            + +++ +G+  +S  ELR  ++ +             +   + E ++             
Sbjct: 1008 LSLIQTVGANCLSGSELRQFVKLL-------------QPEHSPEVLLKILSSMAKSPPTP 1054

Query: 810  RFMDFSSRRNGHASVRISLGDRSWPPAAGYSFMCWL---RFTGIEGKTKGGRSRPA---- 862
             + +F+  +     +R+ + +R+WPP  GY+ M WL   +F  +        S       
Sbjct: 1055 PYFEFNLSKIPFGYIRVPITERAWPPTNGYTIMFWLYIDKFPTVNNNNNNNNSSNNSNNS 1114

Query: 863  ---------------LRIFMVESVEEKGTVLAELYLNDSGLLTLATGPSS--LLAFKGVR 905
                           + +  + S ++K ++   +YL + G++T+    SS  ++     +
Sbjct: 1115 NNSNNNNNNNNNNDQIDLVHIYSDDKKSSLY--IYLKN-GIITVNIINSSKYVIEIPSYK 1171

Query: 906  LEEGLWYHIVIVHNKPNALAGLFQSSVASLYVNGNLRHTGKLGYSPSSF--GKTIQAVIG 963
              EG WYHI IVH +      L   +   L+V+G L++T      P+    G  +   IG
Sbjct: 1172 FVEGKWYHIGIVHAR-----RLLGGTDFKLFVDGFLKYTATKAQYPAQITSGSMLICDIG 1226

Query: 964  IPPQLSDVSSSTWQMTGCYLFEEVLPSQAVCLVYALGRGYRGLFQDTDLLRFVP---YEA 1020
            +  Q    + S W++   YL E+ L ++ +  +Y LG  Y   F+     RF P   YE 
Sbjct: 1227 VSNQNRFPTDSIWRIGTFYLLEDSLGAKHINTIYFLGPNYASNFKG----RFSPYQTYEI 1282

Query: 1021 CGGGNLAVLEGLETAS--AGVNVQKGGDAAKYRIDGSGAVWELERLVSFWIQLSNKKLIF 1078
                NL  ++ L+       +N+ K       +ID +  +  L          ++ KLI 
Sbjct: 1283 VNSANLMAIKDLDYGDQLGPLNLAK----VSMQIDENKILVGL---------CASNKLIR 1329

Query: 1079 SFDXXXXXXXXXXXXSIVNLVE----PLSAAASPLGGLPRI------------------- 1115
            + +             I  L +     L+  +SP G  P +                   
Sbjct: 1330 TNNSSKVVYNEIFNGIINELSQNHGVALNVFSSPNGTSPNLTGLQNNNNNNNNSGGSNSK 1389

Query: 1116 GRLVGDVEILNPCSF--------------------GDSMRKVGGMXXXXXXXXXXXTGEM 1155
              L G VEI+N                         DS++K+GGM           + E 
Sbjct: 1390 KDLEGRVEIINQADLTTKLRGVLIGSVEAFRRNKVADSIKKIGGMPISLLLLEKANSEET 1449

Query: 1156 XXXXXXXXXXXXYYNPRNTYDMLACRGYHLLVLFLHRR--IRLFEVQDLELLFQI 1208
                         Y+P NT++M    GY LL   L ++  + LF    LELLF +
Sbjct: 1450 LFDSLGLLVGLIQYHPTNTHEMSQINGYELLAWVLKKKASLGLFNSNILELLFDL 1504



 Score = 95.9 bits (237), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 100/426 (23%), Positives = 186/426 (43%), Gaps = 63/426 (14%)

Query: 1905 KATPLVEATLEAVPLHIGGDIAVVFQGLCLYRVMNFLERRLQRDDEEAHKKLDRARWSSN 1964
            KA  ++E  LE  P     +  +++    L  +M  +E  + + +       D  R  SN
Sbjct: 2146 KAISIIEMVLEGAPTTATDEEFILYHSRILLDLMYVVETNITKTE-----FFDNERVHSN 2200

Query: 1965 LDAFSSLVVDRVYMGAFSDSAGVLKVLEFLLSMLQLANKHGRVEEAMTTGRSLLSLARGG 2024
            L   SS++VDRV +     +  ++      L ++++  K              L   R G
Sbjct: 2201 LIKLSSMLVDRVNLDQLVKNNKIIIAKRIFLFIVKILEK--------------LEADRVG 2246

Query: 2025 FKQLEPFVQSLLRNTNRMLLFCFLPSPTTNEELTSSNTGLLAKGGLDITLVLQLLISHKK 2084
               L+  VQSL ++ NR++L+  L + TT+                D++ V   +I+H++
Sbjct: 2247 ---LQKTVQSLYKSLNRIILY--LINHTTDT---------------DLSFVANHIINHQR 2286

Query: 2085 LVLCPGNVDSEFLQCLLVNIVPLLQDPRQAVRTLAVDACKVLLHYRK----EALEDILVL 2140
            ++    N+DS+F+      +  L+   +      ++   ++LL  +     E+L  +L L
Sbjct: 2287 IIFSENNLDSDFMNAFCYPLYKLVISDQHEHVDNSIKLWRLLLSLKTSSYIESLATVLQL 2346

Query: 2141 RHASG------EALDVFHGGFDKLL------ASNSIGFYTWFDDAHDAIGRVLEQRASLA 2188
            + +SG      E +D+   GF+ L       A N+  F  W +D    I +V E+     
Sbjct: 2347 KVSSGSNQRQSEIIDL-KPGFELLRNTSGNGAFNNDEFKLWINDNIQTITQVFEENPKKQ 2405

Query: 2189 WMQFIGGAARFNSSR-LKNFEVRRKREMGRRMKDASKADGRHWEQMLER--RVALDMVRD 2245
             + F     + +S   L + + RR   + ++ +   K D  H E+  +   + A   VR 
Sbjct: 2406 HLSFKNNEKKHSSEHTLPSLKSRRTERLSKKQRQDRK-DQSHQEEKSKHITKKAQYFVR- 2463

Query: 2246 SLSAELRLMRQVKYGWVIHAENEWQDHIQQLMHERGLWPVVKPVAESDNEWQLCSTEGPY 2305
            S S   + ++Q++         +W++   Q+  ER +W   +P     ++W+L STEGPY
Sbjct: 2464 SESDRRKKIKQLESDKQKFNAIQWENMRAQITRERAVWGPSEP--HPLDKWKLDSTEGPY 2521

Query: 2306 RMRKKL 2311
            RMRKK+
Sbjct: 2522 RMRKKM 2527



 Score = 59.7 bits (143), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 26/151 (17%)

Query: 239 FLALLDTLIDLAQVG------PVEESE-PGDLNYNKAKAVAIQSRCFPIFDGTRFKSNES 291
           F  LLD++  L  +G      PVE S  P   + N  K ++ Q+  +   +G  FK    
Sbjct: 451 FEQLLDSICSLVYIGYGNVSLPVENSSVPYQTSINNIKEISNQN--YISKNGNAFK---- 504

Query: 292 LTDGKVRDLFAVQVLQDIFLKSGNLNSQVEVLDRLLRLLASHMDNYLVVQELRTLSLFIL 351
                        VL+  FLKS    ++V++LDR+L + +S+  N++++Q   TL+ FI 
Sbjct: 505 -------------VLERYFLKSNYEENRVKILDRILSVYSSNTVNFILLQHTSTLTKFIQ 551

Query: 352 NMPALPRVLQGQLLKVLEHVVTVVNQVPEQE 382
              +L   L+  ++K++  VVTV+N VP QE
Sbjct: 552 EYESLSNGLKYHVMKIVCFVVTVLNCVPFQE 582

 Score =  476 bits (1226), Expect = e-134,   Method: Compositional matrix adjust.
 Identities = 309/926 (33%), Positives = 459/926 (49%), Gaps = 108/926 (11%)

Query: 2461 LERGEKIRFRYNCERVAGLDKHDGIFLIGERCLYIIENYFIDSAGRICEKGGEGELSVID 2520
            +E G+ I+  YN  R+ GL+  +GI L+G++ LY+++N+F+ S   I +       S+ID
Sbjct: 1734 IESGDSIQDVYNVSRIFGLEATEGILLLGKQYLYLMDNFFLRSDNEIVDVNDN---SIID 1790

Query: 2521 Q--ALGVKTSISVVFESTQTATWSDTENTWPGGKAWACSGGAWGKEKLSSGRQMPHSWRM 2578
            +         +  +  S +       EN W                              
Sbjct: 1791 ERDPYLQLLHLQSLSSSGKVRRHISKENNW-----------------------------H 1821

Query: 2579 WKLDSVHELLKRWYQLRPVAIELFSMDGCNDLLVF-HKEERDEVFKNLLS----INLPRS 2633
            W    +  +LKR+Y LR V +ELF  DG + L +  + + RD +++ L++     ++  +
Sbjct: 1822 WDFIDLSLVLKRFYLLRDVGLELFFKDGRSFLTILSNTKNRDSLYQKLVARAPGADVLST 1881

Query: 2634 SRLETAIS-------GVSK-LDSNEGGRLFKTMAKSFSKRWQNGEISNFQYLMHLNTLAG 2685
            S   T++S       G S  L S     L  +     +KRW+  EISNF YL  +NTLAG
Sbjct: 1882 SHFATSMSRDLGKANGKSNFLSSKLANALSFSTTHPATKRWERREISNFNYLQIVNTLAG 1941

Query: 2686 RGYNDLTQYPVFPWVLADYESEELNLSNPTVYRRLDKPMGALSLEREDVFRKRYD---NW 2742
            R YNDLTQYPVFPWV+ADY S+EL+L+NP  YR   KPMGA   ERE  F +RYD     
Sbjct: 1942 RTYNDLTQYPVFPWVIADYTSKELDLNNPKTYRNFCKPMGAQHPERESQFNERYDLLLGL 2001

Query: 2743 DDPEIPKFHYGSHYSSAGTVLFYLIRLPPFSQENLKLQGGQFDHADRLFTNIRDTWLSAS 2802
            +D +   FHYG+HYSSA  V  YLIRL PF    L LQGGQFDHADRLF +I   W S+S
Sbjct: 2002 NDSQQQPFHYGTHYSSAMIVCSYLIRLRPFVDSYLALQGGQFDHADRLFYSIEQAWRSSS 2061

Query: 2803 QGNTADVKELVPEFFYLPEFLENKFDLDLGTKQS-GEKVDDVVLPPWAKGSAREFIRKHR 2861
            + N ADV+EL+PEFFYL E   N    D G++Q     ++DV+LPPWAKG    F++K+R
Sbjct: 2062 KENMADVRELIPEFFYLSEMFINGNGFDFGSRQKESTPINDVILPPWAKGDPAIFVQKNR 2121

Query: 2862 EALESQYVSENLHHWIDLIFGYRQRGQAAVDATNVFYYLTYEGAVDIDSVRDPALKASTL 2921
            EALES+YVS +LH WIDL+FG +QRG  AV ATNVF++L+Y+GA+D++++ +    A+ +
Sbjct: 2122 EALESKYVSAHLHEWIDLVFGCKQRGDEAVAATNVFHHLSYQGAIDLENIENEFELAAAV 2181

Query: 2922 AQINHFGQTPRQLFLKPHPGRKCQ-QKVP-----FGHVLRSSQLL--APQEIRNATTSIA 2973
              I++FGQTP+Q+F KPHP R       P     FG    S  LL  +   I      +A
Sbjct: 2182 GIIHNFGQTPKQVFKKPHPQRGPDFTDTPLGPYLFGRFEDSIHLLFQSCSPIIRICKKVA 2241

Query: 2974 QIVV--SHDKVFSVGHNRLLKPRSYSKYIAWGFPDNSLRFVSYDQDRLLSTHEGLHDGTI 3031
             I    S D+V +   +    P   + ++AWG  DN+++ +S   D+     E LH   I
Sbjct: 2242 HIQYDPSKDEVGAFAAD--YTPLGPNTFLAWGRVDNTVQLISDQLDKQPVMFEELHSEKI 2299

Query: 3032 VCAGFSRDGRTLVTGGEDGVASVWRLRKDGVRNQRRLHLQRALCAHSDSVTCLSVCQPYN 3091
                 + D RT +T   D    +W L         +  L+R L  H   +TC++VC+ ++
Sbjct: 2300 THV-VACDERTFLTASLDLTLRLWTL---STNKPIKASLKRVLYGHRYRITCVTVCKAFS 2355

Query: 3092 LVVTGSSDCTVIFWDLSTLEFVRQLPQLPAPASAVHTNEMTGEIVTAAGTMLVVWSVNGD 3151
            ++V+G +   +I WDL+  EFV  L     P   +  N    EI  + G    V +VNG 
Sbjct: 2356 IIVSGDAGGNLIIWDLNRAEFVSSLSVYKLPIQTIAVNARNAEIAFSTGFYCCVVNVNGK 2415

Query: 3152 CLAALNVSRLASEA------IVSITSPVLSDWMETGWYVTGHQNGAIKLWRIDYASFAQX 3205
             L    +SR+ +E            +   S+W+    ++TGH +G I++W     S A+ 
Sbjct: 2416 ILVKDKLSRIYNENSDENILCSCFYTGANSEWLHKNLFITGHPDGIIRIWEKRLQSNAKL 2475

Query: 3206 XXXXXXXXXXXXNVCFTGGTPEYHLVLHKVLKSHT-----------QPVTALHLSPDLKQ 3254
                                P++   L + L+ HT           Q +  +  +   + 
Sbjct: 2476 EAEKN-----------NADRPKWRFHLLRQLQ-HTKGLGRNRVATRQNIITITPNGQARG 2523

Query: 3255 LYSGDAGGHVTSWVLSTLDGS-----SVQPETCPWCQDVLDVAQLKRYCRNCGKFS-CQR 3308
            +++GD  G V SW+L     +         E C  C     + + +  CR CG  + C  
Sbjct: 2524 IFAGDDKGQVFSWMLPDTTSNVHLEKDNTSELCSLCDSRFSLMEWRSQCRACGNSNVCSD 2583

Query: 3309 CGESAPVVELGYVDPVPICWSCSQHV 3334
            C      V +     +  C+ C + +
Sbjct: 2584 C------VSMLKDTNIKTCYECYRQM 2603

 Score =  471 bits (1212), Expect = e-132,   Method: Compositional matrix adjust.
 Identities = 275/727 (37%), Positives = 395/727 (54%), Gaps = 57/727 (7%)

Query: 2584 VHELLKRWYQLRPVAIELFSMDGCNDLLVFHKEERDEVFKNLLSINLPRSSRLETAISGV 2643
            + EL +  + L+ +A+E+F  +G +  LVF+  +R + FK+  S         + ++ G 
Sbjct: 2468 MRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCS--------FQPSLKGK 2519

Query: 2644 SKLDSNEGGRLFKTMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYNDLTQYPVFPWVLAD 2703
            +  +     R +    +   ++WQ  +ISNF+YLM+LNT AGR  ND  QYPVFPWVLAD
Sbjct: 2520 ATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLAD 2579

Query: 2704 YESEELNLSNPTVYRRLDKPMGALSLEREDVFRKRYDNWDDPE---IPKFHYGSHYSSAG 2760
            Y SE LNL+NP ++R L KPMGA + ER+  F +R+   +  E     + HY +HYSSA 
Sbjct: 2580 YTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAI 2639

Query: 2761 TVLFYLIRLPPFSQENLKLQGGQFDHADRLFTNIRDTWLSASQGNTADVKELVPEFFYLP 2820
             V  YL+R+PPF+Q    LQGG FD ADR+F +++ TW SAS+ N +DV+EL PEFFYLP
Sbjct: 2640 IVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESASRENMSDVRELTPEFFYLP 2699

Query: 2821 EFLENKFDLDLGTKQSGEKVDDVVLPPWAKGSAREFIRKHREALESQYVSENLHHWIDLI 2880
            EFL N   ++ G  Q G  + DV LPPWA G  R+FI  HR+ALES +VS NLHHWIDLI
Sbjct: 2700 EFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLI 2759

Query: 2881 FGYRQRGQAAVDATNVFYYLTYEGAVDIDSVRDPALKASTLAQINHFGQTPRQLFLKPHP 2940
            FGY+Q+G AAVDA N+F+   Y   +D+ S+ DP +K++ L  +++FGQ P+QLF KPHP
Sbjct: 2760 FGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHP 2819

Query: 2941 GRKCQQKV-----------------PFGHVLRSSQLLAPQEI------------RNATTS 2971
             R    K                  PF + L+S   L P ++             +   +
Sbjct: 2820 ARTAAGKPLPGKDVSTPVSLPGHPQPFFYSLQS---LRPSQVTVKDMYLFSLGSESPKGA 2876

Query: 2972 IAQIVVSHDKVFSVGHNRLLKPRSYSKYIAWGFPDNSLRFVSYDQDRLLSTHEGLHD-GT 3030
            I  IV +   + +V  N++L P  +++  +WGF D S    SY  D++L T E L   G 
Sbjct: 2877 IGHIVSTEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGR 2936

Query: 3031 IVCAGFSRDGRTLVTGGEDGVASVWRLRKDGVRNQRRLHLQRALCAHSDSVTCLSVCQPY 3090
             +CA       T+VT G   V  VW L     R  R L L++AL  H+ +VTCL+    +
Sbjct: 2937 CLCA-VCPSPTTIVTSGTSTVVCVWELSMTKGR-PRGLRLRQALYGHTQAVTCLAASVTF 2994

Query: 3091 NLVVTGSSDCTVIFWDLSTLEFVRQLPQLPAPASAVHTNEMTGEIVTAAGTMLVVWSVNG 3150
            +L+V+GS DCT I WDL  L  V +LP      SA+  ++++G IV+ AG  L +W+VNG
Sbjct: 2995 SLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNG 3054

Query: 3151 DCLAALNVSRLASEAIVSITSPVLSDWMETGWYVTGHQNGAIKLWRIDYASFAQXXXXXX 3210
              LA++  +     AI          W  +   +TG Q+G +++W+ +    +       
Sbjct: 3055 QPLASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMS-VPGRPA 3113

Query: 3211 XXXXXXXNVCFTGGTPEYHLVLHKVL---------KSHTQP-VTALHLSPDLKQLYSGDA 3260
                        G   E +L L + L          S T P VTAL +S +  +L  GD 
Sbjct: 3114 GEEPPAQPPSPRGHKWEKNLALSRELDVSIALTGKPSKTSPAVTALAVSRNHTKLLVGDE 3173

Query: 3261 GGHVTSW 3267
             G +  W
Sbjct: 3174 RGRIFCW 3180