Score =  641 bits (1654), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 443/1371 (32%), Positives = 669/1371 (48%), Gaps = 197/1371 (14%)

Query: 2046 KATPLVEATLEAVPLHIGGDIAVVFQGLCLYRVMNFLERRLQRDDEEAHKKLDRAR---- 2101
            K TPL++  LEA P          FQ   L  VM+ L        E+A   +        
Sbjct: 1981 KQTPLIDLLLEASPERSTRTQQKEFQTHVLDSVMDHLLAADVLLGEDASLPITSGGSYQV 2040

Query: 2102 WSSNLDAFSSLVVDRVYMGAFSDSAGVLKVLEFLLSMLQLANKHGRVEEAMTTGRSLLSL 2161
              +N+  F+  VVD+++ G F+  + +L  ++F++ ++  + +  +       G SL   
Sbjct: 2041 LVNNVFYFTQRVVDKLWQGMFNKESKLL--IDFIIQLIAQSKRRSQ-------GLSL--- 2088

Query: 2162 ARGGFKQLEPFVQSLLRNTNRMLLFCFLPSPTTNEELTSSNTGLLAKGGLDITLVLQLLI 2221
                         ++    NR +L+ F    +   +       LL          L++L 
Sbjct: 2089 ------------DAVYHCLNRTILYQF----SRAHKTVPQQVALLDS--------LRVLT 2124

Query: 2222 SHKKLVLCPGNVDSEFLQCL---LVNI----------------------VPLLQDPRQAV 2256
             ++ L+L PGN D EF+ CL   L+N+                      +P   +P    
Sbjct: 2125 VNRNLILGPGNHDQEFISCLAHCLINLHAGSVEGFGLEAEARMTTWHIMIPSDIEPDGGY 2184

Query: 2257 -------RTLAVDACK----VLLHYRKEALEDILVLRHASGEALDVFHGGFDKLLASNSI 2305
                   R L + A       L+H +K+ LE++  +     +      G  D  LA   I
Sbjct: 2185 SQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVSLPVND-----RGHVDIALARPLI 2239

Query: 2306 ---GFYTWFDD-AHD--AIGR----VLEQRASLAWMQFIGGAARFNSSRLKNFEVRRKRE 2355
               G   W +  AH+   I R    V   ++ L+ +    G ++   SR      R ++E
Sbjct: 2240 EEAGLKCWQNHLAHEKKCISRGEALVPTTQSKLSRVSSGFGLSKLTGSR------RNRKE 2293

Query: 2356 MGRRMKDASKADGRHWEQMLERRVALDMVRDSLSAELRLMRQVKYGWVIHAENEWQDHIQ 2415
             G      S  +   W         + +VRD +  + +  ++ +   + +   EW     
Sbjct: 2294 SGLHKHSPSPQEISQW-----MFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIEC 2348

Query: 2416 QLMHERGLWPVVKSVAESDNEWQLCSTEGPYRMRKKLVRCKPKIDIXXXXXXXXXXXVLP 2475
            +L+ ERGLW     +    ++W L  TEGP RMRKK+VR     D+              
Sbjct: 2349 ELLRERGLWG--PPIGSHLDKWMLEMTEGPCRMRKKMVRN----DMFYNHYPYVPETEQE 2402

Query: 2476 NGQAGFAVDIENPDYDSFFHIFSLGVDSPKKNAAKDYLESFDEEDTESKGREDDANSLST 2535
                  A       YDS  +   L   +P        +ES + E T+ +    +      
Sbjct: 2403 ASVGKPARYRRAISYDSKEYYLRLASGNPAI-VQDAIVESSEGEATQQEPEHGEDTIAKV 2461

Query: 2536 RG--DGTIERSRSAINDSGKSPESIQRSKSDAHGTAPGSSPTKTGXXXXXXXXXXXXXXX 2593
            +G     ++RSRSA +   +  +   + +    G+      T                  
Sbjct: 2462 KGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSIEEEEKTDNAT-------------- 2507

Query: 2594 GEYLIAPYLERGEKIRFRYNCERVAGLDKHDGIFLIGERCLYIIENYFIDSAGRICEKGG 2653
                +   LE GEKI+  Y C RV GLD  +G+ L G+   Y+I+               
Sbjct: 2508 ----LLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDG-------------- 2549

Query: 2654 EGELSVIDQALGVKTSISVVFESTQTATWSDTENTWPGGKAWACSGGAWGKEKLSSGRQM 2713
                                F  T T    D E   P         GA          Q+
Sbjct: 2550 --------------------FTMTATREIRDIETLPPNMHEPIIPRGA-----RQGPSQL 2584

Query: 2714 PHSWRMWKLDSVHELLKRWYQLRPVAIELFSMDGCNDLLVFHKEERDEVFKNLLSINLPR 2773
              +  ++  + + E+ KR Y L+P+A+E+FS DG N LL F K  R++V++  L++ +P 
Sbjct: 2585 KRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAV-VPS 2643

Query: 2774 SSRLETAISGVSKLDSNE-GGRLFKTMA--KSFSKRWQNGEISNFQYLMHLNTLAGRGYN 2830
             +    ++SG     S E G  L  T+   KS ++RW+ GEISNFQYLMHLNTLAGR YN
Sbjct: 2644 LTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYN 2703

Query: 2831 DLTQYPVFPWVLADYESEELNLSNPTVYRRLDKPMGALSLEREDVFRKRYDNWDDP--EI 2888
            DL QYPVFPW+L+DY+SEE++L+NP  +R L KPMGA + ER   ++KRY +W+DP  E 
Sbjct: 2704 DLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGET 2763

Query: 2889 PKFHYGSHYSSAGTVLFYLIRLPPFSQENLKLQGGQFDHADRLFTNIRDTWLSASQGNTA 2948
            P +HYG+HYSSA  V  YL+R+ PF+Q  L+LQGG FD ADR+F ++R+ W SAS+ N A
Sbjct: 2764 PAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMA 2823

Query: 2949 DVKELVPEFFYLPEFLENKFDLDLGTKQSGEKVDDVVLPPWAKGSAREFIRKHREALESQ 3008
            DVKEL+PEFFYLPEFL N  + DLG KQ+G K+ DV+LPPWAKG  REFIR HREALE  
Sbjct: 2824 DVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECD 2883

Query: 3009 YVSENLHHWIDLIFGYRQRGQAAVDATNVFYYLTYEGAVDIDSVRDPALKASTLAQINHF 3068
            YVS +LH WIDLIFGY+Q+G AAV+A NVF++L YEG VDI ++ DP  + +T+  IN+F
Sbjct: 2884 YVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNF 2943

Query: 3069 GQTPRQLFLKPHPGRKCQQ------------------KVPFGHVLRSSQLLAPQEIRNAT 3110
            GQ P+QLF KPHP ++ +                   K+ F H+      L P  ++   
Sbjct: 2944 GQIPKQLFKKPHPPKRVRSRLNGDNIGISVPPGATSDKIFFHHLDNLRPSLTP--VKELK 3001

Query: 3111 TSIAQIVVSHDKVFSVGHNRLLKPRSYSKYIAWGFPDNSLRFVSYDQDRLLSTHEGLHD- 3169
              + QIV +   + +V  N++L P +++K  AWG+ D S R  +Y+ D+ ++ +E L + 
Sbjct: 3002 EPVGQIVCTDKGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEW 3061

Query: 3170 GTIVCAGFSRDGRTLVTGGEDGVASVWRLRKDGVRNQRRLHLQRALCAHSDSVTCLSVCQ 3229
            G I+CA    + + ++TGG   V  VW +        + L L++AL  H+D+VTC +   
Sbjct: 3062 GQILCA-VCPNPKLVITGGTSTVVCVWEMGTSK-EKAKPLTLKQALLGHTDTVTCATASL 3119

Query: 3230 PYNLVVTGSSDCTVIFWDLSTLEFVRQLPQLPAPASAVHTNEMTGEIVTAAGTMLVVWSV 3289
             Y+++V+GS D T I WDL+ L F+ QL    AP SA+  NE+TG+IV+ AGT + VWS+
Sbjct: 3120 AYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSI 3179

Query: 3290 NGDCLAALNVSRLASEAIVSITSPVLSDWMETGWYVTGHQNGAIKLWRIDY 3340
            NG+ + ++N     S+ IV      +++W      VTGH +G ++ WR+++
Sbjct: 3180 NGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEF 3230



 Score = 77.4 bits (189), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 90/417 (21%), Positives = 148/417 (35%), Gaps = 60/417 (14%)

Query: 964  GDRSWPPAAGYSFMCWLRFTGIEGKTKGGRSRPALRIFMVESVEEKGTVLAELYLNDSGL 1023
            G+R +PP +G S+ CW               R    +    S E+    LA +       
Sbjct: 1090 GERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRS 1149

Query: 1024 LTLATGPSSLLAFK---------------------GVRLEEGLWYHIVIVHNKPNALAGL 1062
            L ++T    L  +                      G  + EG W+H+ ++ ++     G+
Sbjct: 1150 LIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELVVEGQWHHLALLMSR-----GM 1204

Query: 1063 FQSSVASLYVNGNLRHTGKLGYSPSSFG----------KTIQAVIGIPPQLSDVSSSTWQ 1112
             ++S A+LY++G L  T KL Y  S+ G           T+ A +G PP    ++S  W+
Sbjct: 1205 LKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWR 1264

Query: 1113 MTGCYLFEEVLPSQAVCLVYALGRGYRGLFQDTDLLRFVPYEACGGGNLAVLEGLETASA 1172
            +   +  EEVLP  +V  +Y LG  Y G FQ            C     A  EG+  +  
Sbjct: 1265 LGPTHFLEEVLPPSSVTTIYELGPNYVGSFQ----------AVCVPCKDAKSEGVTPSPV 1314

Query: 1173 GVNVQKGGDAAKYRIDGSGAVWELERLVSFWIQLSNKKLIFSFDXXXXXXXXXXXXSIVN 1232
             +  ++      Y +  S     + R+   + +L +K +                 + V 
Sbjct: 1315 SLVAEEKVSFGLYALSVSSLT--VARIRKVYNKLDSKAI-----AKQLGISSHENATPVK 1367

Query: 1233 LVEPLSAAASPLGGLPRI--GRLVG--DVEILNPCSFGDSMRKVGGMXXXXXXXXXXXTG 1288
            LV     AA  L G  R     L+G   V    P     +++ +GG              
Sbjct: 1368 LVH---NAAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDV 1424

Query: 1289 EMXXXXXXXXXXXXYYNPRNTYDMLACRGYHLLVLFLHRRIRLFEVQDLELLFQIAA 1345
            E               NP  + +M   +GY LL + L ++  L     L L F +  
Sbjct: 1425 EGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVG 1481



 Score = 58.9 bits (141), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 9/111 (8%)

Query: 3370 HLVLHKVLKSHTQPVTALHLSPDLKQLYSGDAGGHVTSWVLSTLDGSSVQP--------E 3421
            H    +   +H   VTAL +S D  ++  GD+ G V SW +S   G S           +
Sbjct: 3381 HTAFDRKDNTHPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGD 3440

Query: 3422 TCPWCQDVLDVAQLKRYCRNCGKFSCQRCGE-SAPVVELGYVDPVPICWSC 3471
            +C  C     + + + +CRNCG+  CQ+C    + +  L    PV +C +C
Sbjct: 3441 SCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNC 3491

 Score =  636 bits (1640), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 337/840 (40%), Positives = 486/840 (57%), Gaps = 106/840 (12%)

Query: 2612 YNCERVAGLDKHDGIFLIGERCLYIIENYFIDSAGRICEKGGEGELSVIDQALGVKTSIS 2671
            YNC  V G+DK +GI +     +YI + Y+ D           G++S +++ +       
Sbjct: 2816 YNCGSVDGMDKIEGILIFCPVYMYIFDGYYKDE--------NTGDISEVEEKIN------ 2861

Query: 2672 VVFESTQTATWSDTENTWPGGKAWACSGGAWGKEKLSSGRQMPHSWRMWKLDSVHELLKR 2731
                                   W   G       L   +++ H +  W  + + ++LKR
Sbjct: 2862 ---------------------SEWLPEGTV-----LPMKKKIIHYFLKWAYEDIRDVLKR 2895

Query: 2732 WYQLRPVAIELFSMDGCNDLLVFHKE-ERDEVFKNLLSINLPRSSRLETAISGVSKLDSN 2790
             Y LR VA+E+FS DG N+L+V+  E  RDEV+  L++ N+   + +     G++     
Sbjct: 2896 RYLLRQVALEIFSTDGRNNLVVYRDEPTRDEVYHTLVN-NVSSHNTIGGDAQGIT----- 2949

Query: 2791 EGGR--------------------LFKTMAKS--FSKRWQNGEISNFQYLMHLNTLAGRG 2828
             GG+                     F ++ +    + +WQ G+ISNFQYLMHLNTLAGR 
Sbjct: 2950 -GGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLKWQQGQISNFQYLMHLNTLAGRS 3008

Query: 2829 YNDLTQYPVFPWVLADYESEELNLSNPTVYRRLDKPMGALSLEREDVFRKRYDNWDDPE- 2887
            YNDLTQYPVFPWVL+DYESEEL++ +P VYR L KPMGAL   R   FR+R++NWDD E 
Sbjct: 3009 YNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPMGALEESRAQKFRERFENWDDQEP 3068

Query: 2888 ------IPKFHYGSHYSSAGTVLFYLIRLPPFSQENLKLQGGQFDHADRLFTNIRDTWLS 2941
                  +PKFHYG+HYSSA  VL+YLIRL PF+Q  LKLQGG++D  DRLF++I + W S
Sbjct: 3069 NEHGHKVPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQPDRLFSSITEAWAS 3128

Query: 2942 ASQGNTADVKELVPEFFYLPEFLENKFDLDLGTKQSGEKVDDVVLPPWAKGSAREFIRKH 3001
            +SQG+T  V EL+PEF+YL EFL N    + GTKQ GE +DD++LPPWAKGS +EFI+ H
Sbjct: 3129 SSQGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIILPPWAKGSPQEFIKLH 3188

Query: 3002 REALESQYVSENLHHWIDLIFGYRQRGQAAVDATNVFYYLTYEGAVDIDSVRDPALKAST 3061
            R+ALES YVSE+LH WIDLIFGYRQ+G+AA D+ NVFYYLTYEGAV+ID++ DP  KA+T
Sbjct: 3189 RKALESDYVSEHLHEWIDLIFGYRQQGKAADDSLNVFYYLTYEGAVNIDAISDPVEKAAT 3248

Query: 3062 LAQINHFGQTPRQLFLKPHPGRKCQ-QKVPFGHVLRSSQLLAPQEIRNATTSIAQIVVSH 3120
            +AQIN+FGQTP+QLF KPHP R      +PF      ++ L    I++    + QI + +
Sbjct: 3249 IAQINNFGQTPKQLFDKPHPKRNATLMGLPF-----YAKALTGNFIKDIGEPVGQIRLIN 3303

Query: 3121 DKVFSVGHNRLLKPRSYSKYIAWGFPDNSLRFVSYDQDRLLSTHEGLHDGTIVCAGFSRD 3180
            D+   VG N++L P ++SKY+ WG PD S+R+ + D+ ++L  H   HDG + C   + D
Sbjct: 3304 DRATCVGFNKVLLPPNHSKYMLWGLPDGSIRYNTGDKIKVLEDH---HDGPLTCLTATED 3360

Query: 3181 GRTLVTGGEDGVASVWRLRKDGVRNQRRLHLQRALCAHSDSVTCLSVCQPYNLVVTGSSD 3240
            GR  V+GG D +  V+ L        +R  L + L  H+ S+TC+S  +PY+++V+GS D
Sbjct: 3361 GRICVSGGSDSLICVYNL--------KRFSLAKRLSGHTGSITCVSASRPYSIIVSGSDD 3412

Query: 3241 CTVIFWDLSTLEFVRQLPQLPAPASAVHTNEMTGEIVTAAGTMLVVWSVNGDCLAALNVS 3300
             T I WDL+ L +VR L     P S +  ++ TGEIV  +GT + V++VNG+ L     S
Sbjct: 3413 RTCIIWDLNRLCYVRSLDAHEGPISCIGIHDTTGEIVVCSGTTISVYTVNGELLINYKTS 3472

Query: 3301 RLASEAIVSITSPVLSDWMETGWYVTGHQNGAIKLWRIDYAIFAQXXXXXXXXXXXXXNV 3360
            ++A++ I         +W+     +TGH++G +K+W ++  +                N 
Sbjct: 3473 QIANDQITCCIWSKGPEWLGENVLLTGHRDGKVKVWGLETRLLPDNNNSNNNNNNNNNNN 3532

Query: 3361 CFTGGTPEYH---------LVLHKVL---KSHTQPVTALHLSPDLKQLYSGDAGGHVTSW 3408
                  P  +         ++L       +SH+  +T++ L+ D ++ Y+GD  G V  W
Sbjct: 3533 NNATQIPSTNNNKLKFKNVIILRATFSNSQSHSTAITSIFLTNDQQKFYTGDITGRVCMW 3592



 Score =  107 bits (266), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 173/843 (20%), Positives = 315/843 (37%), Gaps = 152/843 (18%)

Query: 597  DCLLSLLKRNEANQTAFRKAHGFDALQPLLLSDIHRTYVLRILSCLISEDTVQSHPEELK 656
            D L  L+  N  N +  R    F+ L   L     R   LRIL  LI  D   +  +E  
Sbjct: 730  DSLFILISENPDNISLIRSFSIFNILLRFLPYSSVRGKSLRILQQLIKYDPEPTQ-KEFD 788

Query: 657  ALLGTTRAGEGQGITFKAKTDILWAVFRILCSNPAAKDVFGEGKGFTLMHTVLESLEDFS 716
             L+    +   +   +  K+DIL A  ++   +  A+D F E  GF  + +V  SLE  S
Sbjct: 789  GLIKVLTSVNKEN--YPMKSDILNATRKLFNISKHARDSFREHGGFVSIISVFISLE--S 844

Query: 717  GAEPR---------QRMEIVNALLHVVTVGVAGHSVNRIRLNDCVLSHAFSAALLKTGLI 767
               P          +++E++ ++    T  + G+ +NR      +    FS+ L+ TG++
Sbjct: 845  SFSPNRKDSRNWDMEKLELIESICRCTTSALCGNVINRENFEQQIGYKTFSSCLIMTGVL 904

Query: 768  CGDYEXXXXXXXXXXCLEKVQSPARNVDSFRAGTWDNEFISVDERRELFNAGLVQVALQL 827
              ++             E + +         +    N+ I      E FN  L  +    
Sbjct: 905  GTEFSKSVVDFIFDMVTENLNA---------SDQISNQMII--NNVESFNVILDIIPHIE 953

Query: 828  FDDFSPKAQLKVVTSVEALSEGSLVNKDRLTLAGCLKMVLEILTPSASYS-----PAIWM 882
              DF    +L++++ +  ++E    N++ L+       +L     + S +     P +  
Sbjct: 954  NKDF----RLQIISRINKMAEYGRYNQEALSKLSIPDWILSRFPSNLSNANDPLQPLL-- 1007

Query: 883  HGMQIVKLLGSYRISSFELRALLRYMWQCRDYTYGQVAQRYIEALEGVVRXXXXXXXXXX 942
              + +++ +G+  +S  ELR  ++ +             +   + E +++          
Sbjct: 1008 --LSLIQTVGANCLSGSELRQFVKLL-------------QPEHSPEVLLKILSSMAKSPP 1052

Query: 943  XXRFMDFSSRRNGHASVRISLGDRSWPPAAGYSFMCWL---RFTGIEGKTKGGRSRPA-- 997
               + +F+  +     +R+ + +R+WPP  GY+ M WL   +F  +        S     
Sbjct: 1053 TPPYFEFNLSKIPFGYIRVPITERAWPPTNGYTIMFWLYIDKFPTVNNNNNNNNSSNNSN 1112

Query: 998  -----------------LRIFMVESVEEKGTVLAELYLNDSGLLTLATGPSS--LLAFKG 1038
                             + +  + S ++K ++   +YL + G++T+    SS  ++    
Sbjct: 1113 NSNNSNNNNNNNNNNDQIDLVHIYSDDKKSSLY--IYLKN-GIITVNIINSSKYVIEIPS 1169

Query: 1039 VRLEEGLWYHIVIVHNKPNALAGLFQSSVASLYVNGNLRHTGKLGYSPSSF--GKTIQAV 1096
             +  EG WYHI IVH +      L   +   L+V+G L++T      P+    G  +   
Sbjct: 1170 YKFVEGKWYHIGIVHAR-----RLLGGTDFKLFVDGFLKYTATKAQYPAQITSGSMLICD 1224

Query: 1097 IGIPPQLSDVSSSTWQMTGCYLFEEVLPSQAVCLVYALGRGYRGLFQDTDLLRFVP---Y 1153
            IG+  Q    + S W++   YL E+ L ++ +  +Y LG  Y   F+     RF P   Y
Sbjct: 1225 IGVSNQNRFPTDSIWRIGTFYLLEDSLGAKHINTIYFLGPNYASNFKG----RFSPYQTY 1280

Query: 1154 EACGGGNLAVLEGLETAS--AGVNVQKGGDAAKYRIDGSGAVWELERLVSFWIQLSNKKL 1211
            E     NL  ++ L+       +N+ K       +ID +  +  L          ++ KL
Sbjct: 1281 EIVNSANLMAIKDLDYGDQLGPLNLAK----VSMQIDENKILVGL---------CASNKL 1327

Query: 1212 IFSFDXXXXXXXXXXXXSIVNLVE----PLSAAASPLGGLPRI----------------- 1250
            I + +             I  L +     L+  +SP G  P +                 
Sbjct: 1328 IRTNNSSKVVYNEIFNGIINELSQNHGVALNVFSSPNGTSPNLTGLQNNNNNNNNSGGSN 1387

Query: 1251 --GRLVGDVEILNPCSF--------------------GDSMRKVGGMXXXXXXXXXXXTG 1288
                L G VEI+N                         DS++K+GGM           + 
Sbjct: 1388 SKKDLEGRVEIINQADLTTKLRGVLIGSVEAFRRNKVADSIKKIGGMPISLLLLEKANSE 1447

Query: 1289 EMXXXXXXXXXXXXYYNPRNTYDMLACRGYHLLVLFLHRR--IRLFEVQDLELLFQIAAC 1346
            E              Y+P NT++M    GY LL   L ++  + LF    LELLF +   
Sbjct: 1448 ETLFDSLGLLVGLIQYHPTNTHEMSQINGYELLAWVLKKKASLGLFNSNILELLFDLIGI 1507

Query: 1347 EAS 1349
              +
Sbjct: 1508 NGN 1510



 Score = 94.0 bits (232), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 100/426 (23%), Positives = 185/426 (43%), Gaps = 63/426 (14%)

Query: 2046 KATPLVEATLEAVPLHIGGDIAVVFQGLCLYRVMNFLERRLQRDDEEAHKKLDRARWSSN 2105
            KA  ++E  LE  P     +  +++    L  +M  +E  + + +       D  R  SN
Sbjct: 2146 KAISIIEMVLEGAPTTATDEEFILYHSRILLDLMYVVETNITKTE-----FFDNERVHSN 2200

Query: 2106 LDAFSSLVVDRVYMGAFSDSAGVLKVLEFLLSMLQLANKHGRVEEAMTTGRSLLSLARGG 2165
            L   SS++VDRV +     +  ++      L ++++  K              L   R G
Sbjct: 2201 LIKLSSMLVDRVNLDQLVKNNKIIIAKRIFLFIVKILEK--------------LEADRVG 2246

Query: 2166 FKQLEPFVQSLLRNTNRMLLFCFLPSPTTNEELTSSNTGLLAKGGLDITLVLQLLISHKK 2225
               L+  VQSL ++ NR++L+  L + TT+                D++ V   +I+H++
Sbjct: 2247 ---LQKTVQSLYKSLNRIILY--LINHTTDT---------------DLSFVANHIINHQR 2286

Query: 2226 LVLCPGNVDSEFLQCLLVNIVPLLQDPRQAVRTLAVDACKVLLHYRK----EALEDILVL 2281
            ++    N+DS+F+      +  L+   +      ++   ++LL  +     E+L  +L L
Sbjct: 2287 IIFSENNLDSDFMNAFCYPLYKLVISDQHEHVDNSIKLWRLLLSLKTSSYIESLATVLQL 2346

Query: 2282 RHASG------EALDVFHGGFDKLL------ASNSIGFYTWFDDAHDAIGRVLEQRASLA 2329
            + +SG      E +D+   GF+ L       A N+  F  W +D    I +V E+     
Sbjct: 2347 KVSSGSNQRQSEIIDL-KPGFELLRNTSGNGAFNNDEFKLWINDNIQTITQVFEENPKKQ 2405

Query: 2330 WMQFIGGAARFNSSR-LKNFEVRRKREMGRRMKDASKADGRHWEQMLER--RVALDMVRD 2386
             + F     + +S   L + + RR   + ++ +   K D  H E+  +   + A   VR 
Sbjct: 2406 HLSFKNNEKKHSSEHTLPSLKSRRTERLSKKQRQDRK-DQSHQEEKSKHITKKAQYFVR- 2463

Query: 2387 SLSAELRLMRQVKYGWVIHAENEWQDHIQQLMHERGLWPVVKSVAESDNEWQLCSTEGPY 2446
            S S   + ++Q++         +W++   Q+  ER +W    S     ++W+L STEGPY
Sbjct: 2464 SESDRRKKIKQLESDKQKFNAIQWENMRAQITRERAVWG--PSEPHPLDKWKLDSTEGPY 2521

Query: 2447 RMRKKL 2452
            RMRKK+
Sbjct: 2522 RMRKKM 2527



 Score = 73.9 bits (180), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 112/508 (22%), Positives = 196/508 (38%), Gaps = 104/508 (20%)

Query: 43  SEQDFKRFWEEFRCGHSDKEKQEALEMALSVFCKLSRRHQNPAQLATSLVD-----TRQF 97
           + Q  K  W+EF    SDK+K   L   L  F  L    +      + +VD     ++ F
Sbjct: 146 TAQKLKLLWQEFLSSKSDKDKVMRLNKLLPYFIGLYEDKK--IDTKSPMVDIFGNNSKSF 203

Query: 98  AFVVARAFIADVDKIKSSTS------------QDTLAKSLIQ-----GKQEETANMLYVL 140
           +F ++R  + D+++I    +            ++T+AK + +       Q     +LY +
Sbjct: 204 SFAISRRLVKDINEIMKQANSPQQPPQPPQLIKETIAKEIYKFFSTTSGQVSGFELLYSI 263

Query: 141 ESLVSPPLD-VQPLLDAGLLSCLVHVLYSFLDLTDDFTKAPGNALGISTFLTESVLQVEG 199
           E L        + + +A + S LV  L  F  +   +T       GI          +E 
Sbjct: 264 EILSESNTSCAEAMAEASIPSMLVRCLQYFFLVP--YTTMMETTKGI----------IEE 311

Query: 200 EVVHILKALGSHLGAAQSLADDDSLQMLFAMVIQRPSSVHLAQLHRHVLQILGNVLSSDD 259
           +++  L  L     A + L   D+L  LFA++       H  +  R  +   G  L+   
Sbjct: 312 KLIRTLCFLSKQKSAIEELQKTDTLSTLFALMSNECPPSH--RPLRAKIGSFGLELTDLY 369

Query: 260 GSCAHYIHRHQLVKMLLRPVKE---FTCEXXXXXXXXXXXXXXXXCVEVSCRPGAGGINL 316
                YI+  +++  +++ +     FT E                 +++          L
Sbjct: 370 PPTITYINSKRVIANIIKDLTNYYMFTPESYVTLCRI--------IIKILSESSKKSTIL 421

Query: 317 REDLQNAHGYQLLVQFGXXXXXXXXXXXXXXXXXXXXXXXXXXXEETSSGQADLSTSFLA 376
            ++ Q   GY  LV                               E+S  +  L   F  
Sbjct: 422 LDEFQRNDGYTFLVD-------------------------SLFRLESSKDKPAL---FEQ 453

Query: 377 LLDTLIDLAQVG------PVEESE-PGDLNYNKAKAVAIQSRCFPIFDGTRFKSNESLTD 429
           LLD++  L  +G      PVE S  P   + N  K ++ Q+      +G  FK       
Sbjct: 454 LLDSICSLVYIGYGNVSLPVENSSVPYQTSINNIKEISNQNYISK--NGNAFK------- 504

Query: 430 GKVRDLFAVQVLQDIFLKSGNLNSQVEVLDRLLRLLASHMDNYLVVQELRTLSLFILNMP 489
                     VL+  FLKS    ++V++LDR+L + +S+  N++++Q   TL+ FI    
Sbjct: 505 ----------VLERYFLKSNYEENRVKILDRILSVYSSNTVNFILLQHTSTLTKFIQEYE 554

Query: 490 ALPRVLQGQLLKVLEHVVTVVNQVPEQE 517
           +L   L+  ++K++  VVTV+N VP QE
Sbjct: 555 SLSNGLKYHVMKIVCFVVTVLNCVPFQE 582

 Score =  475 bits (1222), Expect = e-133,   Method: Compositional matrix adjust.
 Identities = 308/926 (33%), Positives = 458/926 (49%), Gaps = 108/926 (11%)

Query: 2602 LERGEKIRFRYNCERVAGLDKHDGIFLIGERCLYIIENYFIDSAGRICEKGGEGELSVID 2661
            +E G+ I+  YN  R+ GL+  +GI L+G++ LY+++N+F+ S   I +       S+ID
Sbjct: 1734 IESGDSIQDVYNVSRIFGLEATEGILLLGKQYLYLMDNFFLRSDNEIVDVNDN---SIID 1790

Query: 2662 Q--ALGVKTSISVVFESTQTATWSDTENTWPGGKAWACSGGAWGKEKLSSGRQMPHSWRM 2719
            +         +  +  S +       EN W                              
Sbjct: 1791 ERDPYLQLLHLQSLSSSGKVRRHISKENNW-----------------------------H 1821

Query: 2720 WKLDSVHELLKRWYQLRPVAIELFSMDGCNDLLVF-HKEERDEVFKNLLS----INLPRS 2774
            W    +  +LKR+Y LR V +ELF  DG + L +  + + RD +++ L++     ++  +
Sbjct: 1822 WDFIDLSLVLKRFYLLRDVGLELFFKDGRSFLTILSNTKNRDSLYQKLVARAPGADVLST 1881

Query: 2775 SRLETAIS-------GVSK-LDSNEGGRLFKTMAKSFSKRWQNGEISNFQYLMHLNTLAG 2826
            S   T++S       G S  L S     L  +     +KRW+  EISNF YL  +NTLAG
Sbjct: 1882 SHFATSMSRDLGKANGKSNFLSSKLANALSFSTTHPATKRWERREISNFNYLQIVNTLAG 1941

Query: 2827 RGYNDLTQYPVFPWVLADYESEELNLSNPTVYRRLDKPMGALSLEREDVFRKRYD---NW 2883
            R YNDLTQYPVFPWV+ADY S+EL+L+NP  YR   KPMGA   ERE  F +RYD     
Sbjct: 1942 RTYNDLTQYPVFPWVIADYTSKELDLNNPKTYRNFCKPMGAQHPERESQFNERYDLLLGL 2001

Query: 2884 DDPEIPKFHYGSHYSSAGTVLFYLIRLPPFSQENLKLQGGQFDHADRLFTNIRDTWLSAS 2943
            +D +   FHYG+HYSSA  V  YLIRL PF    L LQGGQFDHADRLF +I   W S+S
Sbjct: 2002 NDSQQQPFHYGTHYSSAMIVCSYLIRLRPFVDSYLALQGGQFDHADRLFYSIEQAWRSSS 2061

Query: 2944 QGNTADVKELVPEFFYLPEFLENKFDLDLGTKQS-GEKVDDVVLPPWAKGSAREFIRKHR 3002
            + N ADV+EL+PEFFYL E   N    D G++Q     ++DV+LPPWAKG    F++K+R
Sbjct: 2062 KENMADVRELIPEFFYLSEMFINGNGFDFGSRQKESTPINDVILPPWAKGDPAIFVQKNR 2121

Query: 3003 EALESQYVSENLHHWIDLIFGYRQRGQAAVDATNVFYYLTYEGAVDIDSVRDPALKASTL 3062
            EALES+YVS +LH WIDL+FG +QRG  AV ATNVF++L+Y+GA+D++++ +    A+ +
Sbjct: 2122 EALESKYVSAHLHEWIDLVFGCKQRGDEAVAATNVFHHLSYQGAIDLENIENEFELAAAV 2181

Query: 3063 AQINHFGQTPRQLFLKPHPGRKCQ-QKVP-----FGHVLRSSQLL--APQEIRNATTSIA 3114
              I++FGQTP+Q+F KPHP R       P     FG    S  LL  +   I      +A
Sbjct: 2182 GIIHNFGQTPKQVFKKPHPQRGPDFTDTPLGPYLFGRFEDSIHLLFQSCSPIIRICKKVA 2241

Query: 3115 QIVV--SHDKVFSVGHNRLLKPRSYSKYIAWGFPDNSLRFVSYDQDRLLSTHEGLHDGTI 3172
             I    S D+V +   +    P   + ++AWG  DN+++ +S   D+     E LH   I
Sbjct: 2242 HIQYDPSKDEVGAFAAD--YTPLGPNTFLAWGRVDNTVQLISDQLDKQPVMFEELHSEKI 2299

Query: 3173 VCAGFSRDGRTLVTGGEDGVASVWRLRKDGVRNQRRLHLQRALCAHSDSVTCLSVCQPYN 3232
                 + D RT +T   D    +W L         +  L+R L  H   +TC++VC+ ++
Sbjct: 2300 THV-VACDERTFLTASLDLTLRLWTL---STNKPIKASLKRVLYGHRYRITCVTVCKAFS 2355

Query: 3233 LVVTGSSDCTVIFWDLSTLEFVRQLPQLPAPASAVHTNEMTGEIVTAAGTMLVVWSVNGD 3292
            ++V+G +   +I WDL+  EFV  L     P   +  N    EI  + G    V +VNG 
Sbjct: 2356 IIVSGDAGGNLIIWDLNRAEFVSSLSVYKLPIQTIAVNARNAEIAFSTGFYCCVVNVNGK 2415

Query: 3293 CLAALNVSRLASEA------IVSITSPVLSDWMETGWYVTGHQNGAIKLWRIDYAIFAQX 3346
             L    +SR+ +E            +   S+W+    ++TGH +G I++W       A+ 
Sbjct: 2416 ILVKDKLSRIYNENSDENILCSCFYTGANSEWLHKNLFITGHPDGIIRIWEKRLQSNAKL 2475

Query: 3347 XXXXXXXXXXXXNVCFTGGTPEYHLVLHKVLKSHT-----------QPVTALHLSPDLKQ 3395
                                P++   L + L+ HT           Q +  +  +   + 
Sbjct: 2476 EAEKN-----------NADRPKWRFHLLRQLQ-HTKGLGRNRVATRQNIITITPNGQARG 2523

Query: 3396 LYSGDAGGHVTSWVLSTLDGS-----SVQPETCPWCQDVLDVAQLKRYCRNCGKFS-CQR 3449
            +++GD  G V SW+L     +         E C  C     + + +  CR CG  + C  
Sbjct: 2524 IFAGDDKGQVFSWMLPDTTSNVHLEKDNTSELCSLCDSRFSLMEWRSQCRACGNSNVCSD 2583

Query: 3450 CGESAPVVELGYVDPVPICWSCSQHV 3475
            C      V +     +  C+ C + +
Sbjct: 2584 C------VSMLKDTNIKTCYECYRQM 2603

 Score =  471 bits (1213), Expect = e-132,   Method: Compositional matrix adjust.
 Identities = 257/648 (39%), Positives = 370/648 (57%), Gaps = 46/648 (7%)

Query: 2725 VHELLKRWYQLRPVAIELFSMDGCNDLLVFHKEERDEVFKNLLSINLPRSSRLETAISGV 2784
            + EL +  + L+ +A+E+F  +G +  LVF+  +R + FK+  S         + ++ G 
Sbjct: 2468 MRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCS--------FQPSLKGK 2519

Query: 2785 SKLDSNEGGRLFKTMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYNDLTQYPVFPWVLAD 2844
            +  +     R +    +   ++WQ  +ISNF+YLM+LNT AGR  ND  QYPVFPWVLAD
Sbjct: 2520 ATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLAD 2579

Query: 2845 YESEELNLSNPTVYRRLDKPMGALSLEREDVFRKRYDNWDDPE---IPKFHYGSHYSSAG 2901
            Y SE LNL+NP ++R L KPMGA + ER+  F +R+   +  E     + HY +HYSSA 
Sbjct: 2580 YTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAI 2639

Query: 2902 TVLFYLIRLPPFSQENLKLQGGQFDHADRLFTNIRDTWLSASQGNTADVKELVPEFFYLP 2961
             V  YL+R+PPF+Q    LQGG FD ADR+F +++ TW SAS+ N +DV+EL PEFFYLP
Sbjct: 2640 IVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESASRENMSDVRELTPEFFYLP 2699

Query: 2962 EFLENKFDLDLGTKQSGEKVDDVVLPPWAKGSAREFIRKHREALESQYVSENLHHWIDLI 3021
            EFL N   ++ G  Q G  + DV LPPWA G  R+FI  HR+ALES +VS NLHHWIDLI
Sbjct: 2700 EFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLI 2759

Query: 3022 FGYRQRGQAAVDATNVFYYLTYEGAVDIDSVRDPALKASTLAQINHFGQTPRQLFLKPHP 3081
            FGY+Q+G AAVDA N+F+   Y   +D+ S+ DP +K++ L  +++FGQ P+QLF KPHP
Sbjct: 2760 FGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHP 2819

Query: 3082 GRKCQQKV-----------------PFGHVLRSSQLLAPQEI------------RNATTS 3112
             R    K                  PF + L+S   L P ++             +   +
Sbjct: 2820 ARTAAGKPLPGKDVSTPVSLPGHPQPFFYSLQS---LRPSQVTVKDMYLFSLGSESPKGA 2876

Query: 3113 IAQIVVSHDKVFSVGHNRLLKPRSYSKYIAWGFPDNSLRFVSYDQDRLLSTHEGLHD-GT 3171
            I  IV +   + +V  N++L P  +++  +WGF D S    SY  D++L T E L   G 
Sbjct: 2877 IGHIVSTEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGR 2936

Query: 3172 IVCAGFSRDGRTLVTGGEDGVASVWRLRKDGVRNQRRLHLQRALCAHSDSVTCLSVCQPY 3231
             +CA       T+VT G   V  VW L     R  R L L++AL  H+ +VTCL+    +
Sbjct: 2937 CLCA-VCPSPTTIVTSGTSTVVCVWELSMTKGR-PRGLRLRQALYGHTQAVTCLAASVTF 2994

Query: 3232 NLVVTGSSDCTVIFWDLSTLEFVRQLPQLPAPASAVHTNEMTGEIVTAAGTMLVVWSVNG 3291
            +L+V+GS DCT I WDL  L  V +LP      SA+  ++++G IV+ AG  L +W+VNG
Sbjct: 2995 SLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNG 3054

Query: 3292 DCLAALNVSRLASEAIVSITSPVLSDWMETGWYVTGHQNGAIKLWRID 3339
              LA++  +     AI          W  +   +TG Q+G +++W+ +
Sbjct: 3055 QPLASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTE 3102