Query: CNT0038884
Subject: sp|Q6ZS30|NBEL1_HUMAN Neurobeachin-like protein 1 OS=Homo sapiensOS=Dictyostelium discoideum GN=lvsC PE=3 SV=2
Score = 451 bits (1159), Expect = e-126, Method: Compositional matrix adjust.
Identities = 271/770 (35%), Positives = 400/770 (51%), Gaps = 148/770 (19%)
Query: 2047 VTAIYATRYLLQHTALEIFFADAAPPVFLNFASHQVAKDVALKITSSKHVGSKGKAKHQI 2106
+ ++ RYLL+ +A+EIF D +F NF ++ K V KI S K SK
Sbjct: 1776 IKDVHLRRYLLRGSAIEIFMRDKTNYLF-NFKKNERNK-VYNKINSVKREFSKEPTL--- 1830
Query: 2107 HFVDRKRAIDLAEKARDCWRRRECSNFDYLMILNTLSGRSYNDLTQYPVFPWILSDYSSE 2166
D+ +KA W+ R SNFDYLM LNT++GR+YNDLTQYPVFPW+++DY+S
Sbjct: 1831 ------SPSDMLKKATSEWQARRISNFDYLMTLNTIAGRTYNDLTQYPVFPWVIADYTSP 1884
Query: 2167 ALDLSSPSVYRDLAKPVGALDEKRFQVFEERYNNFTDPDIPSFHYGSHYSSMGIVLFYLL 2226
LDL+ +RDL+KP+GAL+EKR ++F++RY +F DP IP F+YGSHYSS GIVLFYL+
Sbjct: 1885 VLDLNKAETFRDLSKPIGALNEKRLEIFKDRYESFDDPVIPKFYYGSHYSSAGIVLFYLI 1944
Query: 2227 RLEPFSSFHRTLQGGKFDHADRLFHSIQNTYANCLTNTSDVKEIIPEFFYMPEFLVNTNS 2286
RLEPF++ LQGG+FDH DR+F SI + N LT+++DVKE+IPEF+YMPEFL N N
Sbjct: 1945 RLEPFTTQFLNLQGGRFDHPDRMFDSIALAWDNSLTSSTDVKELIPEFYYMPEFLTNHNH 2004
Query: 2287 YYIGVKQDGQHLNNVILPPWAKVGLDLIRFQSHILIFFQGSPEEFIRLNREALESEHTSE 2346
G+KQ+G + +V+LPPWA SP +FIR+NREALES++ S
Sbjct: 2005 INFGIKQNGIGIEDVLLPPWA------------------SSPSDFIRINREALESDYVSS 2046
Query: 2347 NLHRWIDLIFGYKQRGKPAVEAANIFYYLTYEGTVELETMEDARQRASVEDQIANFGQTP 2406
+LH WIDLIFG KQRGK A E N+FYYLTYEG+V+++++ED R + E QI NFGQTP
Sbjct: 2047 HLHEWIDLIFGIKQRGKQAKEVFNVFYYLTYEGSVDIDSIEDETTRRATESQINNFGQTP 2106
Query: 2407 IQLFKKKHPKRGPPVPLLRPLYYSPASTTLVSTIPSR-SLSFGKSDEDHPVLYIGHCD-- 2463
QLF KKH + P+ + + +++ T P++ F K +P++Y+ +
Sbjct: 2107 TQLFSKKHHIQRDPL--------NESHISILKTPPNQLQAYFLKITNKNPIVYVYIPEPN 2158
Query: 2464 --------GKIISVTSQMVVSSRMWLXXXXXXXXXXXXXXXXXXXYGLGSEEWPCHKVRG 2515
K+ + ++ W P K+
Sbjct: 2159 PIMSYLVADKVTVIDKSRTTTNHKWFPST------------------------PNDKISP 2194
Query: 2516 YFTDFKLMSLTDGQTVQSLCQHKDVV---TCASVAADGSIVATGSRDTTVMVWETQLSSN 2572
+ + S T + L DV C ++ +DG V + + W+
Sbjct: 2195 FTFELDPSSTTKRRI--GLPFANDVTISPNCFAITSDGRYVISCAH------WDNSF--- 2243
Query: 2573 RTKRSDSKLAVSDKPRHV--LCGHDDAVTCVVVRTELDLVVSGSEDGTC----------- 2619
KL+ D + + + H D VTC+ + ++ +++GS+D T
Sbjct: 2244 -------KLSFVDSAKLIQSVVKHKDTVTCLSLASDGQTLITGSKDTTVMVWRIATTNKS 2296
Query: 2620 -----------ILY------------------------------TLRQGRYVRSLVHPSR 2638
ILY L+ G YVRS+ P +
Sbjct: 2297 GAPKFNDVPDHILYGHDDEITCVDVNVGLDISISGSKDGTCIIHNLKHGEYVRSIYLPRQ 2356
Query: 2639 KSISLLVVSPHGLVGLFSNKDLNFHSFSVNGKHLASAELNGRLSCMELSSCGEFVVCGGD 2698
ISL+ +S G + ++S DL + +S+NG L + + + RL + +S E+++ GG+
Sbjct: 2357 SPISLIAISNQGYIVIYSQADLMIYLYSINGGLLKTVDTHERLHSIIISKDSEYLITGGE 2416
Query: 2699 QGYVTVRKLHSLELVHRYDTAGSPIVSLCV-TPEDCFLVGTRDGRFLIYA 2747
+G V +R L +L+ + G+PI SL + + + +VG DGR LI A
Sbjct: 2417 RGVVVIRTLFNLKPTNHKLVFGTPIHSLAMASDQKHLMVGLEDGRLLIIA 2466
Score = 163 bits (413), Expect = 1e-38, Method: Compositional matrix adjust.
Identities = 132/521 (25%), Positives = 233/521 (44%), Gaps = 68/521 (13%)
Query: 555 LLSILRDVLQCDFPYYQALFREVECFVHIVSLLNEAYPEEHGKRLCLEVIATLIHLLKGN 614
+L +R +++ + P Q LF++ F+ IV+L+N +E LC V+ T+I L+ N
Sbjct: 1 MLDGIRQIIKNN-PKKQNLFKKFRVFIKIVNLVNADDKKERLSVLCHSVLRTVILLMANN 59
Query: 615 EASKLAFRSLVGPGYKMLETLLVNRYGYPTQDLLNALWNML--------------NEDVI 660
K FR+ +G Y ++ L++ G ++ +N L++M+ N D
Sbjct: 60 PKIKKHFRNHIG--YDTIKDLIIKSEGIVSETTMNILFDMIVDGEFDIEYKYVIQNPDSC 117
Query: 661 VLLLNFIHLCDPETQLKALDTFLQLLEESTANQSSCVRAGLLCSLMDWFSSENESVVLHK 720
+L+ N + + Q + LD F ++E+ T NQS C L+ +L++ V K
Sbjct: 118 LLIFNLLKYFPTKLQHEILDRFTVMVEKCTTNQSVCCNCHLIYNLLEAIYKGQPMEVTTK 177
Query: 721 LCHFIKLAGGHSMAGKEMRRMFSLLRSTSSS----KNNLILSTFKSMLSEQ--GPSVFFE 774
+ I+ G HS+ +E++++F LL+S + +L+T +++ + + GP V+F+
Sbjct: 178 ILKLIERLGIHSVTVRELKKLFGLLKSEQGDYLPPTTSALLTTLQNISNSRNPGPQVYFD 237
Query: 775 LSGKNSGIGIKTPFRWPINKGFSFMCWIRLESV-----SSEGMMSLFSFLTGDGKG---- 825
GK+S I + T +WP KGFSF W+R+ES + E LFSFL+ G G
Sbjct: 238 FDGKDSCIILPTFDKWPFPKGFSFCTWVRIESFVDPTGTPEYKPRLFSFLSDSGCGIEVL 297
Query: 826 ---------------CAAFISADKFFIEVLSLFSVAILVFLTLALSCHSTNYYTFRYPKV 870
A + F+E F V+++ + L +S + Y
Sbjct: 298 FIYQQLQVLTVNNHQSKAVFQSPPTFVEREWYF-VSVVYSINL-ISSNEIRIYINGQQSA 355
Query: 871 YDPVSCTIG---------ANATADQSSGFFSPLCGQLGPVYLFDDVLTPGQVEGVFMLGA 921
+ I N + S PL GQ+G +FD+ L+P Q++ ++ LG
Sbjct: 356 KSSIKLNISGTLWNHFKIGNNSKKMSGERECPLYGQMGAFNIFDESLSPSQIQAIYTLGP 415
Query: 922 GYMYSFLPSEAGCIPANMXXXXXXXXXXXXXXXMIFGYNALASSGRVLFDVAPVSEQSDA 981
+ SF E A+ + YN A G + D P +
Sbjct: 416 NFNTSFQDVEGSTKSAH-------TFESSLTSHLFLNYNCRALDGDLCLDNTP--DIGGD 466
Query: 982 VSHEATIMSGTQLCYRCLVQNNIHCVGGITVFFPLLTRFRH 1022
+++AT++S C +++ I+C+GGI V FPL+ + +
Sbjct: 467 KNYDATLVS-INPCVSRDIKDIIYCLGGIKVLFPLIQQINN 506
Score = 81.3 bits (199), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 51/127 (40%), Positives = 67/127 (52%), Gaps = 15/127 (11%)
Query: 1745 FLRAAKRQWVSAVETLNTETNDTRSLELRESKALEEQSLTVLNSIH----NSELSRRAAY 1800
+L K++ V LNT+ + S E KA + LNSIH E RRA +
Sbjct: 1497 WLEKRKKKLTKVV--LNTDEKEAESFNAAERKADND-----LNSIHVKLWMPECERRALH 1549
Query: 1801 QLKEDAEEQAVASQWCLIFRNLTDERGPWSSTTFPSDTLVWWKLDKTEDPLRRRLKLKRN 1860
K QW I R+LT+ERGPW +T +++V WKLDKTE+ R R+KLKRN
Sbjct: 1550 LYKARELRNQTTVQWRKILRSLTNERGPWGTT----ESIVHWKLDKTENSSRMRIKLKRN 1605
Query: 1861 YHFDQKL 1867
Y FD+ L
Sbjct: 1606 YKFDEHL 1612
Score = 67.4 bits (163), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 52/192 (27%), Positives = 93/192 (48%), Gaps = 12/192 (6%)
Query: 1102 NALSD-LLVRETVLKVYLNPSAWIYAPYVIQRELFLSL--INFLETRKYGNVCGVSRFLD 1158
N +SD LV E + LN WI Y +QR L + + I F + + ++ V LD
Sbjct: 604 NQISDPTLVEEVYSNLMLNFCIWIKTKYELQRNLLVIIKQIVFEKYDQVSDIITVQLILD 663
Query: 1159 MLHQFYW-DKPK------HRKMSKTVGTRDRPRQEELSQLRILILSLAETAIRDHMSVSD 1211
+++ FYW D K H +K + ++ RP + +LR ++ + +R H +D
Sbjct: 664 IMNDFYWYDDSKNEAHRNHHFFNKDILSK-RPSISNIRELRQILFEVLRILLR-HQKSTD 721
Query: 1212 AKSLISFIDRNDDLICVEEVLQMLLGLLGDPIFLSSFLECVHSLGGIHIFLNLLSRQQEV 1271
+++I F+ D + E+++ +LGL G+ F + + LGG +FL LL E
Sbjct: 722 IQAIIKFLIYCKDYQQLIEMMEFVLGLNGNGHNCQQFFDEIMGLGGTDVFLTLLKIDDEG 781
Query: 1272 IRLLALHVLGSL 1283
+R A+ ++ +
Sbjct: 782 VRNTAIQLISKI 793
Query: CNT0038884
Subject: sp|Q55DM1|LVSA_DICDI BEACH domain-containing protein lvsAGN=NBEAL1 PE=2 SV=3
Score = 395 bits (1014), Expect = e-109, Method: Compositional matrix adjust.
Identities = 277/789 (35%), Positives = 400/789 (50%), Gaps = 155/789 (19%)
Query: 2046 QVTAIYATRYLLQHTALEIFFADAAPPVFLNFASHQVAKDVALKITS---SKHVGSK--G 2100
Q+ I+ RY L+ +ALEIF D + FLNF K+V KI S S H + G
Sbjct: 1937 QIREIHLRRYNLRRSALEIFHVDQSN-YFLNFK-----KEVRNKIYSRLLSLHSPNSYYG 1990
Query: 2101 KAKHQIHFVDRKRAIDLAEKARDCWRRRECSNFDYLMILNTLSGRSYNDLTQYPVFPWIL 2160
Q F +A L +K W RE SNFDYL+ +NT++GR+YNDL QYPVFPWIL
Sbjct: 1991 SRSPQELF----KASGLTQK----WVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWIL 2042
Query: 2161 SDYSSEALDLSSPSVYRDLAKPVGALDEKRFQVFEERYNNFTDP--DIPSFHYGSHYSSM 2218
DY+SE LDL++P+V+RDL+KP+G ++EK + E+Y NF DP I FHYG+HYS+
Sbjct: 2043 QDYTSEELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNS 2102
Query: 2219 GIVLFYLLRLEPFSSFHRTLQGGKFDHADRLFHSIQNTYANCLTNTSDVKEIIPEFFYMP 2278
V+ YL+R+EPF++ H LQ G+FD ADR FHSI T+ + N DVKE+IPEFFY P
Sbjct: 2103 AGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFP 2162
Query: 2279 EFLVNTNSYYIGVKQDGQHL-NNVILPPWAKVGLDLIRFQSHILIFFQGSPEEFIRLNRE 2337
EFL N N + +G Q + L N+VILP WAK S E+FI +R+
Sbjct: 2163 EFLENQNQFNLGRLQISKELVNDVILPKWAK------------------SAEDFIYKHRK 2204
Query: 2338 ALESEHTSENLHRWIDLIFGYKQRGKPAVEAANIFYYLTYEGTVELETMEDARQRASVED 2397
ALESE+ S +LH WIDLIFGYKQRG AVEA N+FYY +YEG V+L+ + D ++R ++E
Sbjct: 2205 ALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEG 2264
Query: 2398 QIANFGQTPIQLFKKKHPKR-GPPVPLLRPLYYSPASTTLVSTIPSRSLSFGKSDEDH-P 2455
I NFGQTP QL K+ HP R + +P ++ L +P F + D P
Sbjct: 2265 MINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPELKSFFIEGISDGIP 2324
Query: 2456 VLYIGHCDGKIISVTSQ----MVVSSRMWLXXXXXXXXXXXXXXXXXXXYGLGSEEWPCH 2511
+L + S SQ ++++ M Y +G+ W +
Sbjct: 2325 LLKATIPKNQYRSFMSQGSPELLITISM--------------------NYVIGTHGWLPY 2364
Query: 2512 --KVRGYFTDFKLMSLTDGQTVQSL----CQHKDVVTCASVAADGS--IVATGSRDTTVM 2563
+ YFT K ++T+ +T +S+ ++ + V + + + + G D ++
Sbjct: 2365 DRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQ 2424
Query: 2564 VWETQLSSNRTKRSDSKLAVSDKPRHVLCGHDDAVTCVVVRTELDLVVSGSEDGTCILY- 2622
V +S + K +S RH+ D VTC+ ++SGS D TC+++
Sbjct: 2425 V----MSLTKGK------IISHIIRHM-----DIVTCLATDYCGIHLISGSRDTTCMIWQ 2469
Query: 2623 --------------------------------------------------TLRQGRYVRS 2632
T+++G+Y+R+
Sbjct: 2470 ITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRT 2529
Query: 2633 LVHPSRKSISL----LVVSPHGLVGLFSN-------KDLN-FHSFSVNGKHLASAELNGR 2680
L P S+ L L +S G + ++S+ KD N H FS+NGK+L S L +
Sbjct: 2530 LRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQ 2589
Query: 2681 LSCMELSSCGEFVVCGGDQGYVTVRKLHSLELVHRYDTAGSPIVSLCVTPE-DCFLVGTR 2739
+S ++ GE +V G QG++++R LHSL L PI +CVT E LVG
Sbjct: 2590 VS--DICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLE 2647
Query: 2740 DGRFLIYAV 2748
DG+ ++ V
Sbjct: 2648 DGKLIVVGV 2656
Score = 63.9 bits (154), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 87/328 (26%), Positives = 145/328 (44%), Gaps = 60/328 (18%)
Query: 549 IDIVLDLLSILRDVLQC-DFPYYQALFREVECFVHIVSLLNEAYPEEHGKRLCLEV--IA 605
I + + +L+ + +L C D P QA+F CF H++ LL + G+ CL + I
Sbjct: 323 IALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQ-GQLDCLAISTIQ 381
Query: 606 TLIHLLKGNEASKLAFRSLVGPGYKMLETLLVNRYGYPTQDLLNALWNML---------- 655
L ++ + A+K F+ +G + MLE L G P +LL L NM
Sbjct: 382 ALTAVMNKSPAAKEVFKERIGYTH-MLEVL--KSLGQPPLELLKELMNMAVEGDHTSVGI 438
Query: 656 ----NEDVIVLLLNFIHLCDPETQLKALDTFL-----QLLEESTANQSSCVRAGL---LC 703
N ++LL+ ++ PE Q L F+ ++ + ++++CV A + +
Sbjct: 439 LGISNVQPLLLLIQWL----PELQSHDLQIFISDWLKRICCINRQSRTTCVNANMGIRII 494
Query: 704 SLMDWFSSENESVVLHKLCHFIKLA-----GGHSMAGKEMRRMFSLLRSTSSSKNNLILS 758
+D SS LH+ C +A G S++ +E+RR+ LLR S + ++
Sbjct: 495 ETLDLHSS------LHQTCAENLIAIHGSLGSQSVSSEEIRRLLRLLRVDESESVHPYVT 548
Query: 759 -------TFKSMLSEQGPSVFFELSGKNSGIGIKTPFRWPINKGFSFMCWIRLES----- 806
T LS + +F LS +GI + +WP FSF W L+
Sbjct: 549 PVTRAILTMARKLSLESALQYFNLSHSMAGISVPPIQKWP-GSAFSFSAWFCLDQDQLTL 607
Query: 807 -VSSEG--MMSLFSFLTGDGKGCAAFIS 831
++++G L+SF TG G G AFI+
Sbjct: 608 GIANKGGKRKQLYSFFTGSGMGFEAFIT 635
Query: CNT0038884
Subject: sp|Q6VNB8|WDFY3_MOUSE WD repeat and FYVE domain-containing protein 3OS=Dictyostelium discoideum GN=lvsA PE=3 SV=2
Score = 387 bits (994), Expect = e-106, Method: Compositional matrix adjust.
Identities = 262/754 (34%), Positives = 373/754 (49%), Gaps = 164/754 (21%)
Query: 2039 FLFFKSLQVTAIYATRYLLQHTALEIFFADAAPPVFL----------------NFASHQV 2082
FL + + + RYLL+ ALEIF D + + N +SH
Sbjct: 2881 FLKWAYEDIRDVLKRRYLLRQVALEIFSTDGRNNLVVYRDEPTRDEVYHTLVNNVSSHNT 2940
Query: 2083 AKDVALKITSSK--------HVGSKGKAKHQIHFVDRKRAIDLAEKARDCWRRRECSNFD 2134
A IT + H G G + F R L K W++ + SNF
Sbjct: 2941 IGGDAQGITGGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLK----WQQGQISNFQ 2996
Query: 2135 YLMILNTLSGRSYNDLTQYPVFPWILSDYSSEALDLSSPSVYRDLAKPVGALDEKRFQVF 2194
YLM LNTL+GRSYNDLTQYPVFPW+LSDY SE LD+ P VYRDL+KP+GAL+E R Q F
Sbjct: 2997 YLMHLNTLAGRSYNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPMGALEESRAQKF 3056
Query: 2195 EERYNNFTDPD-------IPSFHYGSHYSSMGIVLFYLLRLEPFSSFHRTLQGGKFDHAD 2247
ER+ N+ D + +P FHYG+HYSS IVL+YL+RLEPF+ LQGG++D D
Sbjct: 3057 RERFENWDDQEPNEHGHKVPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQPD 3116
Query: 2248 RLFHSIQNTYANCLT-NTSDVKEIIPEFFYMPEFLVNTNSYYIGVKQDGQHLNNVILPPW 2306
RLF SI +A+ +T V E+IPEF+Y+ EFLVN N + G KQ G+ ++++ILPPW
Sbjct: 3117 RLFSSITEAWASSSQGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIILPPW 3176
Query: 2307 AKVGLDLIRFQSHILIFFQGSPEEFIRLNREALESEHTSENLHRWIDLIFGYKQRGKPAV 2366
AK GSP+EFI+L+R+ALES++ SE+LH WIDLIFGY+Q+GK A
Sbjct: 3177 AK-----------------GSPQEFIKLHRKALESDYVSEHLHEWIDLIFGYRQQGKAAD 3219
Query: 2367 EAANIFYYLTYEGTVELETMEDARQRASVEDQIANFGQTPIQLFKKKHPKRGPPVPLLRP 2426
++ N+FYYLTYEG V ++ + D ++A+ QI NFGQTP QLF K HPKR + L P
Sbjct: 3220 DSLNVFYYLTYEGAVNIDAISDPVEKAATIAQINNFGQTPKQLFDKPHPKRNATLMGL-P 3278
Query: 2427 LYYSPASTTLVSTIPSRSLSFGKSDEDHPVLYIGHCDGKIISVTSQMVVSSRMWLXXXXX 2486
Y + + I PV I ++I+ + V +++ L
Sbjct: 3279 FYAKALTGNFIKDI------------GEPVGQI-----RLINDRATCVGFNKVLL----- 3316
Query: 2487 XXXXXXXXXXXXXXYGLGSEEWPCHKVRGYFTDFKLMSLTDGQTVQSLCQHKDVVTCASV 2546
+GL P +R Y T K+ L D H +TC +
Sbjct: 3317 -----PPNHSKYMLWGL-----PDGSIR-YNTGDKIKVLED--------HHDGPLTCLTA 3357
Query: 2547 AADGSIVATGSRDTTVMVWETQLSSNRTKRSDSKLAVSDKPRHVLCGHDDAVTCVVVRTE 2606
DG I +G D+ + V+ + + +++ + L GH ++TCV
Sbjct: 3358 TEDGRICVSGGSDSLICVYNLK-----------RFSLAKR----LSGHTGSITCVSASRP 3402
Query: 2607 LDLVVSGSEDGTCILYTLRQGRYVRSLVHPSRKSISLLVVSPHGLVGLFSNKDLNFHSFS 2666
++VSGS+D TCI++ L + YVRS L+ H
Sbjct: 3403 YSIIVSGSDDRTCIIWDLNRLCYVRS---------------------------LDAHE-- 3433
Query: 2667 VNGKHLASAELNGRLSCMEL-SSCGEFVVCGGDQGYVTVRKLHSLELVHRYDTA--GSPI 2723
G +SC+ + + GE VVC G ++V ++ EL+ Y T+ +
Sbjct: 3434 ------------GPISCIGIHDTTGEIVVCSGTT--ISVYTVNG-ELLINYKTSQIANDQ 3478
Query: 2724 VSLCVTP-------EDCFLVGTRDGRFLIYAVET 2750
++ C+ E+ L G RDG+ ++ +ET
Sbjct: 3479 ITCCIWSKGPEWLGENVLLTGHRDGKVKVWGLET 3512
Query: CNT0038884
Subject: sp|Q8IZQ1|WDFY3_HUMAN WD repeat and FYVE domain-containing protein 3OS=Mus musculus GN=Wdfy3 PE=1 SV=1
Score = 377 bits (969), Expect = e-103, Method: Compositional matrix adjust.
Identities = 249/706 (35%), Positives = 349/706 (49%), Gaps = 96/706 (13%)
Query: 2041 FFKSLQVTAIYATRYLLQHTALEIFFADAAPPVFLNFAS------HQVAKDVALKITSSK 2094
F + ++ RYLLQ A+E+F D L F +Q V +T S
Sbjct: 2590 IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRN-YLLAFQKGIRNKVYQRFLAVVPSLTDSS 2648
Query: 2095 HVGSKGKAKHQIHFVDRKRAIDLAEKA-RDCWRRRECSNFDYLMILNTLSGRSYNDLTQY 2153
S + + + + EK+ W R E SNF YLM LNTL+GRSYNDL QY
Sbjct: 2649 ESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQY 2708
Query: 2154 PVFPWILSDYSSEALDLSSPSVYRDLAKPVGALDEKRFQVFEERYNNFTDP--DIPSFHY 2211
PVFPWILSDY SE +DL++P +R+LAKP+GA ++R +++RY ++ DP + P++HY
Sbjct: 2709 PVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHY 2768
Query: 2212 GSHYSSMGIVLFYLLRLEPFSSFHRTLQGGKFDHADRLFHSIQNT-YANCLTNTSDVKEI 2270
G+HYSS IV YL+R+EPF+ LQGG FD ADR+FHS++ Y+ N +DVKE+
Sbjct: 2769 GTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKEL 2828
Query: 2271 IPEFFYMPEFLVNTNSYYIGVKQDGQHLNNVILPPWAKVGLDLIRFQSHILIFFQGSPEE 2330
IPEFFY+PEFL N+N++ +G KQ+G L +VILPPWAK G P E
Sbjct: 2829 IPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAK-----------------GDPRE 2871
Query: 2331 FIRLNREALESEHTSENLHRWIDLIFGYKQRGKPAVEAANIFYYLTYEGTVELETMEDAR 2390
FIR++REALE ++ S +LH WIDLIFGYKQ+G AVEA N+F++L YEG V++ + D
Sbjct: 2872 FIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPL 2931
Query: 2391 QRASVEDQIANFGQTPIQLFKKKHPKRG--------------PPVPLLRPLYYSPASTTL 2436
+ + I NFGQ P QLFKK HP + PP +++
Sbjct: 2932 KETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGISVPPGATSDKIFFHHLDNLR 2991
Query: 2437 VSTIPSRSLSFGKSDEDHPVLYIGHCDGKIISVTSQMVVSSRMWLXXXXXXXXXXXXXXX 2496
S P + L PV I D I++V V+ W
Sbjct: 2992 PSLTPVKELK-------EPVGQIVCTDKGILAVEQNKVLIPPAW---------------- 3028
Query: 2497 XXXXYGLGSEEWPCHKVRGYFTDFKLMSLTDGQTVQSLCQHKDVVTCASVAADGSIVATG 2556
+ G + C ++ Y +D + TV + CA V + +V TG
Sbjct: 3029 -NKTFAWGYADLSC-RLGTYESDKAV-------TVYECLSEWGQILCA-VCPNPKLVITG 3078
Query: 2557 SRDTTVMVWETQLSSNRTKRSDSKLAVSDKPRHVLCGHDDAVTCVVVRTELDLVVSGSED 2616
T V VWE S + K K A L GH D VTC ++VSGS D
Sbjct: 3079 GTSTVVCVWEMGTSKEKAKPLTLKQA--------LLGHTDTVTCATASLAYHIIVSGSRD 3130
Query: 2617 GTCILYTLRQGRYVRSLVHPSRKSISLLVVSPHGLVG-LFSNKDLNFHSFSVNGKHLASA 2675
TCI++ L + ++ L R +S L ++ L G + S H +S+NG + S
Sbjct: 3131 RTCIIWDLNKLSFLTQL-RGHRAPVSALCINE--LTGDIVSCAGTYIHVWSINGNPIVSV 3187
Query: 2676 E-LNGR---LSCMELSSCGEF-----VVCGGDQGYVTVRKLHSLEL 2712
GR + C +S E+ +V G G V ++ L++
Sbjct: 3188 NTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQV 3233
Query: CNT0038884
Subject: sp|P50851|LRBA_HUMAN Lipopolysaccharide-responsive and beige-likeOS=Homo sapiens GN=WDFY3 PE=1 SV=2
Score = 376 bits (966), Expect = e-103, Method: Compositional matrix adjust.
Identities = 252/724 (34%), Positives = 354/724 (48%), Gaps = 93/724 (12%)
Query: 2041 FFKSLQVTAIYATRYLLQHTALEIFFADAAPPVFLNFAS------HQVAKDVALKITSSK 2094
F + ++ RYLLQ A+E+F D L F +Q V +T S
Sbjct: 2608 IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRN-YLLAFQKGIRNKVYQRFLAVVPSLTDSS 2666
Query: 2095 HVGSKGKAKHQIHFVDRKRAIDLAEKA-RDCWRRRECSNFDYLMILNTLSGRSYNDLTQY 2153
S + + + + EK+ W R E SNF YLM LNTL+GRSYNDL QY
Sbjct: 2667 ESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQY 2726
Query: 2154 PVFPWILSDYSSEALDLSSPSVYRDLAKPVGALDEKRFQVFEERYNNFTDP--DIPSFHY 2211
PVFPWIL+DY SE +DL++P +R+LAKP+GA ++R +++RY ++ DP + P++HY
Sbjct: 2727 PVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHY 2786
Query: 2212 GSHYSSMGIVLFYLLRLEPFSSFHRTLQGGKFDHADRLFHSIQNT-YANCLTNTSDVKEI 2270
G+HYSS IV YL+R+EPF+ LQGG FD ADR+FHS++ Y+ N +DVKE+
Sbjct: 2787 GTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKEL 2846
Query: 2271 IPEFFYMPEFLVNTNSYYIGVKQDGQHLNNVILPPWAKVGLDLIRFQSHILIFFQGSPEE 2330
IPEFFY+PEFL N+N++ +G KQ+G L +VILPPWAK G P E
Sbjct: 2847 IPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAK-----------------GDPRE 2889
Query: 2331 FIRLNREALESEHTSENLHRWIDLIFGYKQRGKPAVEAANIFYYLTYEGTVELETMEDAR 2390
FIR++REALE ++ S +LH WIDLIFGYKQ+G AVEA N+F++L YEG V++ + D
Sbjct: 2890 FIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPL 2949
Query: 2391 QRASVEDQIANFGQTPIQLFKKKHPKRGPPVPLLRPLYYSPASTTLVSTIPSRSLSFGKS 2450
+ + I NFGQ P QLFKK H PP + L A +++ S + F
Sbjct: 2950 KETATIGFINNFGQIPKQLFKKPH----PPKRVRSRLNGDNAGISVLPGSTSDKIFFHHL 3005
Query: 2451 DE-----------DHPVLYIGHCDGKIISVTSQMVVSSRMWLXXXXXXXXXXXXXXXXXX 2499
D PV I D I++V V+ W
Sbjct: 3006 DNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTW-----------------NK 3048
Query: 2500 XYGLGSEEWPCHKVRGYFTDFKLMSLTDGQTVQSLCQHKDVVTCASVAADGSIVATGSRD 2559
+ G + C ++ Y +D TV + CA + + +V TG
Sbjct: 3049 TFAWGYADLSC-RLGTYESD-------KAMTVYECLSEWGQILCA-ICPNPKLVITGGTS 3099
Query: 2560 TTVMVWETQLSSNRTKRSDSKLAVSDKPRHVLCGHDDAVTCVVVRTELDLVVSGSEDGTC 2619
T V VWE S + K K A L GH D VTC ++VSGS D TC
Sbjct: 3100 TVVCVWEMGTSKEKAKTVTLKQA--------LLGHTDTVTCATASLAYHIIVSGSRDRTC 3151
Query: 2620 ILYTLRQGRYVRSLVHPSRKSISLLVVSPHGLVG-LFSNKDLNFHSFSVNGKHLASAE-L 2677
I++ L + ++ L R +S L + + L G + S H +S+NG + S
Sbjct: 3152 IIWDLNKLSFLTQL-RGHRAPVSALCI--NELTGDIVSCAGTYIHVWSINGNPIVSVNTF 3208
Query: 2678 NGR---LSCMELSSCGEF-----VVCGGDQGYVTVRKLHSLELVHRYDTAGSPIVSLCVT 2729
GR + C +S E+ +V G G V + +E + +T +
Sbjct: 3209 TGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVV---RFWRMEFLQVPETPAPEPAEVLEM 3265
Query: 2730 PEDC 2733
EDC
Sbjct: 3266 QEDC 3269