Query: CNT0003975
Subject: sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiensOS=Dictyostelium discoideum GN=lvsC PE=3 SV=2
Score = 484 bits (1247), Expect = e-136, Method: Compositional matrix adjust.
Identities = 274/689 (39%), Positives = 380/689 (55%), Gaps = 88/689 (12%)
Query: 2179 KDRSWLMSSLHQIFSRRYLLRRSALELFMIDRSNFFFDFGSTEGRRNAYRAIVQARPLQL 2238
K + W + + RRYLLR SA+E+FM D++N+ F+F E RN + + +
Sbjct: 1767 KIKRWPNEMIKDVHLRRYLLRGSAIEIFMRDKTNYLFNFKKNE--RNKVYNKINSVKREF 1824
Query: 2239 SNIYLATQRPEQLLKRTQLMERWARWEISNFEYLMQLNTLAGRSYNDITQYPVFPWILSD 2298
S T P +LK+ W ISNF+YLM LNT+AGR+YND+TQYPVFPW+++D
Sbjct: 1825 SK--EPTLSPSDMLKKA--TSEWQARRISNFDYLMTLNTIAGRTYNDLTQYPVFPWVIAD 1880
Query: 2299 YSSKYLDLADPSSYRDLSKPVGALNPDRLTKFQERYSSFDDPIIPKFHYGSHYSSAGTVL 2358
Y+S LDL ++RDLSKP+GALN RL F++RY SFDDP+IPKF+YGSHYSSAG VL
Sbjct: 1881 YTSPVLDLNKAETFRDLSKPIGALNEKRLEIFKDRYESFDDPVIPKFYYGSHYSSAGIVL 1940
Query: 2359 YYLTRVEPFTTLSIQLQGGKFDHADRMFSDIGSTWNGVLEDMSDVKELVPELFYLPEILT 2418
+YL R+EPFTT + LQGG+FDH DRMF I W+ L +DVKEL+PE +Y+PE LT
Sbjct: 1941 FYLIRLEPFTTQFLNLQGGRFDHPDRMFDSIALAWDNSLTSSTDVKELIPEFYYMPEFLT 2000
Query: 2419 NENSIDFGTTQLGGKLDSVKLPPWAENPVDFIHKHRMALESEHVSAHLHEWIDLIFGYKQ 2478
N N I+FG Q G ++ V LPPWA +P DFI +R ALES++VS+HLHEWIDLIFG KQ
Sbjct: 2001 NHNHINFGIKQNGIGIEDVLLPPWASSPSDFIRINREALESDYVSSHLHEWIDLIFGIKQ 2060
Query: 2479 RGKEAILANNVFFYITYEGTVDVDKITDPVQQRATQDQIAYFGQTPSQLLTTPHLKKMRL 2538
RGK+A NVF+Y+TYEG+VD+D I D +RAT+ QI FGQTP+QL + H +
Sbjct: 2061 RGKQAKEVFNVFYYLTYEGSVDIDSIEDETTRRATESQINNFGQTPTQLFSKKHHIQRDP 2120
Query: 2539 ADVLHLQTIFRNPKEVKPYAV---------------PNPERCNLPAAAMHASSDSVVIVD 2583
+ H+ + P +++ Y + PNP L A D V ++D
Sbjct: 2121 LNESHISILKTPPNQLQAYFLKITNKNPIVYVYIPEPNPIMSYLVA-------DKVTVID 2173
Query: 2584 INAPAAHLAQHKWQPNTPDGQGMPFLFHHGKAIGSSSSGTFMRMFKGPTGSNSDEWHFPR 2643
+ HKW P+TP+ + PF F SS T R+
Sbjct: 2174 ---KSRTTTNHKWFPSTPNDKISPFTFE-----LDPSSTTKRRI---------------- 2209
Query: 2644 ALAFATSGIRSSAIVSITCD-KEIITGGHVDNSIRLISSDGAKALETARGHCAPVTCLAL 2702
L FA S +IT D + +I+ H DNS +L D AK +++ H VTCL+L
Sbjct: 2210 GLPFANDVTISPNCFAITSDGRYVISCAHWDNSFKLSFVDSAKLIQSVVKHKDTVTCLSL 2269
Query: 2703 SPDSNYLVTGSRDTTVLLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLANILADKSRR 2762
+ D L+TGS+DTTV++W +KS
Sbjct: 2270 ASDGQTLITGSKDTTVMVWRIAT-------------------------------TNKSGA 2298
Query: 2763 RRI-EGPIHILRGHFKEIVCCCVSSDLGIVVSCSQSSDVLLHSVRKGRLIRRLVGVEAHA 2821
+ + P HIL GH EI C V+ L I +S S+ ++H+++ G +R +
Sbjct: 2299 PKFNDVPDHILYGHDDEITCVDVNVGLDISISGSKDGTCIIHNLKHGEYVRSIYLPRQSP 2358
Query: 2822 ICL---SSDGIIMTWNKTSHNLSTFTLNG 2847
I L S+ G I+ +++ + +++NG
Sbjct: 2359 ISLIAISNQGYIVIYSQADLMIYLYSING 2387
Score = 110 bits (276), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 101/425 (23%), Positives = 171/425 (40%), Gaps = 76/425 (17%)
Query: 250 VMLNSRAAIVAGELIPWLPWESDSESIMSPRTRMVRGLLAILQACTRNRAMCSMAGLLGV 309
V+ N + ++ L+ + P + E I+ T MV + CT N+++C L+
Sbjct: 110 VIQNPDSCLLIFNLLKYFPTKLQHE-ILDRFTVMV-------EKCTTNQSVCCNCHLIYN 161
Query: 310 LLGSAERIFTEEVDSSEPMKWDGTPLCYCIQYLAGHSLSVIDLRKWFQVIRSTLTTVW-- 367
LL E + +PM+ T + I+ L HS++V +L+K F +++S
Sbjct: 162 LL--------EAIYKGQPMEV-TTKILKLIERLGIHSVTVRELKKLFGLLKSEQGDYLPP 212
Query: 368 ATPLMLAMEKAMVGKESRGPSCTFEFDXXXXXXXXXXXXRWPFTSGYAFATWIYVESFAD 427
T +L + + + GP F+FD +WPF G++F TW+ +ESF D
Sbjct: 213 TTSALLTTLQNISNSRNPGPQVYFDFDGKDSCIILPTFDKWPFPKGFSFCTWVRIESFVD 272
Query: 428 TLNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGEGT-AHMPRLFSFLSADNQGVEAY 486
GT + PRLFSFLS G+E
Sbjct: 273 P-----------------------------------TGTPEYKPRLFSFLSDSGCGIEVL 297
Query: 487 FHAQFLVVESGSGRGKKASLHFTHAFKPQCWYFIGLEHTCKHGLLGKAESELRLYIDGAL 546
F Q L V + + KA F + WYF+ + ++ L+ + +E+R+YI+G
Sbjct: 298 FIYQQLQVLTVNNHQSKAVFQSPPTFVEREWYFVSVVYSI--NLI--SSNEIRIYINGQQ 353
Query: 547 YETRPFEFPRISRPLAFCCIGTNPPPTMAGLQRRRRQCPLFAEMGPVYIFKEPIGPEKMA 606
+ IG N M+G R+CPL+ +MG IF E + P ++
Sbjct: 354 SAKSSIKLNISGTLWNHFKIGNNSKK-MSG----ERECPLYGQMGAFNIFDESLSPSQIQ 408
Query: 607 RLASRGGDILPSFGNGAGLPWLATNDHLQSMAEESSLLDAEIAGCIHLLYHPNLLSGRFC 666
+ + G + SF + G + + ++ + + L Y+ L G C
Sbjct: 409 AIYTLGPNFNTSFQDVEG------------STKSAHTFESSLTSHLFLNYNCRALDGDLC 456
Query: 667 PDASP 671
D +P
Sbjct: 457 LDNTP 461
Query: CNT0003975
Subject: sp|Q6ZQA0|NBEL2_MOUSE Neurobeachin-like protein 2 OS=Mus musculusGN=NBEAL2 PE=1 SV=2
Score = 476 bits (1226), Expect = e-134, Method: Compositional matrix adjust.
Identities = 316/929 (34%), Positives = 467/929 (50%), Gaps = 184/929 (19%)
Query: 1990 WKLDFMESSARMRQCLRRNYKGSDHFGAAANFEDHMDMKHDRENVIDPSNAPILAAEAIS 2049
WKL E+ +RMR L N+ +F+ H++ R+N+ P+ E S
Sbjct: 1827 WKLSSAETYSRMRLKLVPNH----------HFDPHLEASALRDNL---GEVPLTPTEEAS 1873
Query: 2050 MG-GINEEDEQADIDNLVESEAIDMEQNGKNQPKSSGMAEQPPQASTEYIDTPIANNQDV 2108
+ + +E + + L++ + Q G+++ +AE ++TP+
Sbjct: 1874 LPLAVTKEAKVSTPPELLQED-----QLGEDE-----LAE---------LETPMEA---- 1910
Query: 2109 VQGPSAVAPGYVPSELDE---RIVLELSSSMVRPLRVVRGTFQITTRRINFIVDNTEC-- 2163
+ELDE ++VL +V + VV G ++TT+ + F +TE
Sbjct: 1911 -------------AELDEQREKLVLSAECQLVTVVAVVPGLLEVTTQNVYFYDGSTERVE 1957
Query: 2164 --NGDGLDCSSEIRDQEKDRSWLMSSLHQIFSRRYLLRRSALELFMIDRSNFFFDF---- 2217
G G D ++ L ++ RR+ LRRSALELF ID++N+F +F
Sbjct: 1958 TEEGIGYDFRRP-----------LAQLREVHLRRFNLRRSALELFFIDQANYFLNFPCKV 2006
Query: 2218 --------------------GSTEGRRNAYRAIVQARPLQLSNIYLATQRPEQLLKRTQL 2257
T+ R Y +++ RP S YL+++ P+++L+ + L
Sbjct: 2007 GTTPVSSPSQTPRPQPGPIPPHTQVRNQVYSWLLRLRPP--SQGYLSSRSPQEMLRASGL 2064
Query: 2258 MERWARWEISNFEYLMQLNTLAGRSYNDITQYPVFPWILSDYSSKYLDLADPSSYRDLSK 2317
++W + EISNFEYLMQLNT+AGR+YND++QYPVFPW+L DY S LDL++P+ +RDLSK
Sbjct: 2065 TQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSNPAVFRDLSK 2124
Query: 2318 PVGALNPDRLTKFQERYSSFDDP--IIPKFHYGSHYSSAGTVLYYLTRVEPFTTLSIQLQ 2375
P+G +NP +E+Y SF+DP I KFHYG+HYS+A V++YL RVEPFT+L +QLQ
Sbjct: 2125 PIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQ 2184
Query: 2376 GGKFDHADRMFSDIGSTWNGVLEDMSDVKELVPELFYLPEILTNENSIDFGTTQLGG-KL 2434
G+FD +DR F + + W LE +DVKEL+PE FY P+ L N+N D G QL K+
Sbjct: 2185 SGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKV 2244
Query: 2435 DSVKLPPWAENPVDFIHKHRMALESEHVSAHLHEWIDLIFGYKQRGKEAILANNVFFYIT 2494
V LPPWA +P DFI +HR ALESE+VSAHLHEWIDLIFGYKQRG A A NVF+Y T
Sbjct: 2245 GDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWIDLIFGYKQRGPAAEEALNVFYYCT 2304
Query: 2495 YEGTVDVDKITDPVQQRATQDQIAYFGQTPSQLLTTPHLKKMRLADVLHL--------QT 2546
YEG VD+D +TD +++A + I+ FGQTP QLL PH ++ + H +
Sbjct: 2305 YEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEPHPTRLSAEEAAHRLARLDTNSPS 2364
Query: 2547 IFRNPKEVKPY-------AVP-----NPERCNLPAAAMHASSDSVVIVDINAPAAHLAQH 2594
IF++ E+K + VP P R + S D +V V + L H
Sbjct: 2365 IFQHLDELKAFFAEVVSDGVPLVLALVPHR-QPHSFITQGSPDLLVTVSAS---GLLGTH 2420
Query: 2595 KWQPNTPDGQGMPFLFHHGKAIGSSSSGTFMRMFKGPTGSNSDEWHFPRALAFATSGIRS 2654
W P + F F +GS + R+ GP W SG+
Sbjct: 2421 SWLPYDRNISNY-FSFSKDPTMGSHKT---QRLLSGP-------W-------VPGSGVSG 2462
Query: 2655 SAIVSITCDKEIITGGHVDNSIRLISSDGAKALETARGHCAPVTCLALSPDSNYLVTGSR 2714
A+ K + +GGH D S+R+ + K L H VTCLAL YL++GSR
Sbjct: 2463 QALAVAPDGKLLFSGGHWDGSLRVTALPRGKLLSQLSCHLDVVTCLALDTCGIYLISGSR 2522
Query: 2715 DTTVLLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLANILADKSRRRRIEGPIHILRG 2774
DTT ++W L+ LA K P+ +L G
Sbjct: 2523 DTTCMVW-----------------------RLLHQGGLSVGLAPK--------PVQVLYG 2551
Query: 2775 HFKEIVCCCVSSDLGIVVSCSQSSDVLLHSVRKGRLIRRLVGVEA------HAICLSSDG 2828
H + C +S++L + VS S+ V++H+VR+G+ + L + A + L S+G
Sbjct: 2552 HGAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLGATFPGPIFHLALGSEG 2611
Query: 2829 IIMT----WNK----TSHNLSTFTLNGIL 2849
I+ W + +++L +++NG L
Sbjct: 2612 QIVVQSSAWERPGAQVTYSLHLYSVNGKL 2640
Query: CNT0003975
Subject: sp|E7FAW3|NBEL2_DANRE Neurobeachin-like protein 2 OS=Danio rerioGN=Nbeal2 PE=2 SV=2
Score = 476 bits (1224), Expect = e-133, Method: Compositional matrix adjust.
Identities = 293/796 (36%), Positives = 426/796 (53%), Gaps = 134/796 (16%)
Query: 2122 SELDER---IVLELSSSMVRPLRVVRGTFQITTRRINFIVDNTECNGDGLDCSSEIRDQE 2178
+ELDE+ +VL +V + VV G +ITT+ + F +TE + +E
Sbjct: 1899 AELDEKREKLVLSAECQLVTVVAVVPGLLEITTQHVYFYDGSTE----------RVETEE 1948
Query: 2179 ---KDRSWLMSSLHQIFSRRYLLRRSALELFMIDRSNFFFDF------------------ 2217
D ++ L ++ RR+ LRRSALELF ID+SN+F +F
Sbjct: 1949 GIGHDFRRPLAQLREVHLRRFNLRRSALELFFIDQSNYFLNFPHKVAASSASSPCQAPRP 2008
Query: 2218 ------GSTEGRRNAYRAIVQARPLQLSNIYLATQRPEQLLKRTQLMERWARWEISNFEY 2271
T+ R Y +++ RP + YL+++ P ++L+ + L ++W + EISNFEY
Sbjct: 2009 QLYPIPSHTQLRNQVYSLLLRLRPP--TQGYLSSRSPLEMLRASGLTQKWVQREISNFEY 2066
Query: 2272 LMQLNTLAGRSYNDITQYPVFPWILSDYSSKYLDLADPSSYRDLSKPVGALNPDRLTKFQ 2331
LMQLNT+AGR+YND++QYPVFPW+L DY S LDL++P+ +RDLSKP+G +NP +
Sbjct: 2067 LMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPVLDLSNPAVFRDLSKPIGVVNPKHAQLVR 2126
Query: 2332 ERYSSFDDP--IIPKFHYGSHYSSAGTVLYYLTRVEPFTTLSIQLQGGKFDHADRMFSDI 2389
E+Y SF+DP I KFHYG+HYS+A V++YL RVEPFT+L +QLQ G+FD +DR F +
Sbjct: 2127 EKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSV 2186
Query: 2390 GSTWNGVLEDMSDVKELVPELFYLPEILTNENSIDFGTTQLGG-KLDSVKLPPWAENPVD 2448
+ W LE +DVKEL+PE FY P+ L N+N D G QL K+ V LPPWA +P D
Sbjct: 2187 AAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWAGSPED 2246
Query: 2449 FIHKHRMALESEHVSAHLHEWIDLIFGYKQRGKEAILANNVFFYITYEGTVDVDKITDPV 2508
FI KHR ALESE+VS HLHEWIDLIFGYKQRG A A NVF+Y TYEG VD+D + D
Sbjct: 2247 FIQKHRQALESEYVSTHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVADER 2306
Query: 2509 QQRATQDQIAYFGQTPSQLLTTPHLKKM-------RLADV-LHLQTIFRNPKEVKPY--- 2557
+++A + I+ FGQTP QLL PH ++ RLA + + +IF+N ++K +
Sbjct: 2307 ERKALEGIISNFGQTPCQLLKEPHPPRLSAEEAANRLARLDTNSPSIFQNLNQLKAFFAE 2366
Query: 2558 ----AVP-----NPERCNLPAAAMHASSDSVVIVDINAPAAHLAQHKWQPNTPDGQGMPF 2608
AVP P R + + +SSD +V V + + L H W P + F
Sbjct: 2367 VVSEAVPLVLALVPHRQSH-SFITQSSSDMLVTV---SASGLLGTHTWLPYDRNINNY-F 2421
Query: 2609 LFHHGKAIGSSSSGTFMRMFKGPTGSNSDEWHFPRALAFATSGIRSSAIVSITCDKEIIT 2668
F +GS ++ GP S+ SG+ + A+ K + +
Sbjct: 2422 TFSKDPTMGSPK---VQKLLSGPWVSD--------------SGVSAQALAVAPDGKLLFS 2464
Query: 2669 GGHVDNSIRLISSDGAKALETARGHCAPVTCLALSPDSNYLVTGSRDTTVLLWXXXXXXX 2728
GGH D S+R+ S + L H VTCLAL YL++GSRDTT ++W
Sbjct: 2465 GGHWDGSLRVTSLPRGRLLNQLSRHLDIVTCLALDTCGIYLISGSRDTTCMVW------- 2517
Query: 2729 XXXXXXXXXXXXXXXXXXXXXXXLANILADKSRRRRIEGPIHILRGHFKEIVCCCVSSDL 2788
L+ LA K P+ +L GH + C +S++L
Sbjct: 2518 ----------------RLLQQSGLSAGLAPK--------PVQVLYGHVAAVSCVAISTEL 2553
Query: 2789 GIVVSCSQSSDVLLHSVRKGRLI-------RRLVGVEAHAICLSSDGIIMTWN------- 2834
+ VS S+ V++H+VR+G+ + L G +H + L ++G I+ +
Sbjct: 2554 DMAVSGSEDGTVIIHTVRRGQFVAALRPPGATLPGPISH-LALGAEGQIVVQSSACERPG 2612
Query: 2835 -KTSHNLSTFTLNGIL 2849
+ +++L +++NG L
Sbjct: 2613 AQVTYSLHLYSVNGRL 2628
Score = 54.7 bits (130), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 3/99 (3%)
Query: 471 RLFSFLSADNQGVEAYFHAQFLVVESGSGRGKKASLHFTH-AFKPQCWYFIGLEHTCKHG 529
+L+SF ++ G EA+F A +V + R + +++ +F W+ + + H G
Sbjct: 629 QLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYVTVNLPEVSFADSAWHCVAIVHV--PG 686
Query: 530 LLGKAESELRLYIDGALYETRPFEFPRISRPLAFCCIGT 568
+++ + ++ DG L +T PF FP +S P + CCIG+
Sbjct: 687 RRPFSQNLVNVFKDGHLVKTVPFRFPSLSEPFSSCCIGS 725
Query: CNT0003975
Subject: sp|Q6ZS30|NBEL1_HUMAN Neurobeachin-like protein 1 OS=Homo sapiensGN=nbeal2 PE=1 SV=1
Score = 473 bits (1218), Expect = e-133, Method: Compositional matrix adjust.
Identities = 291/770 (37%), Positives = 407/770 (52%), Gaps = 119/770 (15%)
Query: 2126 ERIVLELSSSMVRPLRVVRGTFQITTRRINFIVDNTECNGDGLDCSSEIRDQEK----DR 2181
E++VL ++ + VV G ++TT + F D SSE + E+ D
Sbjct: 1989 EKLVLSEDCELITIVAVVPGRLEVTTHHLYFY-----------DGSSEKEETEEGIGFDF 2037
Query: 2182 SWLMSSLHQIFSRRYLLRRSALELFMIDRSNFFFDFGSTEGRRN-AYRAIVQARPLQLSN 2240
+S L ++ RRY LRRSALELF ID+S++F +F +G RN Y I+ RP L
Sbjct: 2038 KRPLSQLREVHLRRYNLRRSALELFFIDQSHYFINF--RKGVRNKVYSRILGLRPPNL-- 2093
Query: 2241 IYLATQRPEQLLKRTQLMERWARWEISNFEYLMQLNTLAGRSYNDITQYPVFPWILSDYS 2300
Y ++ P++LLK + L RW EISNFEYLMQLNT+AGR+YND++QYPVFPW+L DY+
Sbjct: 2094 FYFGSRSPQELLKASNLTHRWVCREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYT 2153
Query: 2301 SKYLDLADPSSYRDLSKPVGALNPDRLTKFQERYSSFDDPI--IPKFHYGSHYSSAGTVL 2358
S LDL DP+ +RDLSKP+G +NP +E+Y SF+DP I KFHYG+HYS+A V+
Sbjct: 2154 SAELDLDDPAVFRDLSKPIGVVNPRHAQNVREKYESFEDPTGTIDKFHYGTHYSNAAGVM 2213
Query: 2359 YYLTRVEPFTTLSIQLQGGKFDHADRMFSDIGSTWNGVLEDMSDVKELVPELFYLPEILT 2418
+Y+ R EPFT+L IQLQ GKFD ADR F I + W +E +DVKEL+PE FY PE L
Sbjct: 2214 HYMIRTEPFTSLHIQLQSGKFDCADRQFHSIAAAWQARMESPADVKELIPEFFYFPEFLE 2273
Query: 2419 NENSIDFGTTQLGG-KLDSVKLPPWAENPVDFIHKHRMALESEHVSAHLHEWIDLIFGYK 2477
N N D G Q+ K+++V LPPWA + DFI KHR ALESEHVSAHLHEWIDLIFGYK
Sbjct: 2274 NMNGFDLGCLQISQEKVNNVLLPPWASSREDFIRKHRKALESEHVSAHLHEWIDLIFGYK 2333
Query: 2478 QRGKEAILANNVFFYITYEGTVDVDKITDPVQQRATQDQIAYFGQTPSQLLTTPHLKKM- 2536
QRG EA+ A NVF+Y TYEG VD+D I + +++A + I+ FGQTP QLL PH +M
Sbjct: 2334 QRGPEAVEALNVFYYCTYEGAVDLDAIANETERKALEGIISNFGQTPCQLLKEPHPPRMS 2393
Query: 2537 --------------------RLADVLHLQTIFRNPKEVKPYAVPNPERCNLPAAAMHASS 2576
+L+ + + + + + VP N + + S
Sbjct: 2394 AENAFRRAARLDILPPNLFDQLSKLRSFKEVVSDGLALVQAVVPR----NQTRSFIIPGS 2449
Query: 2577 DSVVIVDINAPAAHLAQHKWQPNTPDGQGMPFLFHHGKAIGSSSSGTFMRMFKGPTGSNS 2636
D +V V N + H W P + K I + + + P+ SN
Sbjct: 2450 DILVTVSAN---GMIGTHSWLP-------------YDKNIAN-----YFTFTRDPSVSNP 2488
Query: 2637 DEWHFPRALAFATSGIRSSAIVSITCDKEII-TGGHVDNSIRLISSDGAKALETARGHCA 2695
F F+ S ++ ++ D ++ +GGH D S+R+ AK + H
Sbjct: 2489 KTQRFLSG-PFSPGVEMGSQVLVVSSDGRLLFSGGHWDCSLRVTMLGKAKLVGRICRHID 2547
Query: 2696 PVTCLALSPDSNYLVTGSRDTTVLLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLANI 2755
VTCLAL YL++GSRDTT ++W
Sbjct: 2548 VVTCLALDLCGIYLISGSRDTTCMVWQVLQQ--------------------------GGF 2581
Query: 2756 LADKSRRRRIEGPIHILRGHFKEIVCCCVSSDLGIVVSCSQSSDVLLHSVRKGRLIRRL- 2814
+ S R PI +L GH +E+ C +S++L + +S S+ V++HSVR+G+ + L
Sbjct: 2582 SSGLSPR-----PIQVLCGHDQEVTCVAISTELDMAISGSKDGTVIVHSVRRGQYLWTLR 2636
Query: 2815 ---------------VGVEAHAICLSSDGIIMTWNKTSHNLSTFTLNGIL 2849
VG+E H I + + + K + L +++NG L
Sbjct: 2637 PPCENCVSAPVAQLEVGMEGH-IVMQTVLEGRSAGKERYALHVYSVNGTL 2685
Score = 54.3 bits (129), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Query: 471 RLFSFLSADNQGVEAYFHAQ-FLVVESGSGRGKKASLHFTHAFKPQCWYFIGLEHTCKHG 529
+L+SF +A G EA+F + LVV + + A H F W+ + + H
Sbjct: 660 QLYSFFTASGTGFEAFFTTEEVLVVAVCTKKEYMAVSLPEHPFNDCAWHSVAIVHVPGRR 719
Query: 530 LLGKAESELRLYIDGALYETRPFEFPRISRPLAFCCIGT 568
G ++ + +Y+DG +T P FP ++ P CCIG+
Sbjct: 720 PFG--QNVVTVYVDGVQCKTAPLRFPSLNEPFTSCCIGS 756
Query: CNT0003975
Subject: sp|P50851|LRBA_HUMAN Lipopolysaccharide-responsive and beige-likeGN=NBEAL1 PE=2 SV=3
Score = 464 bits (1194), Expect = e-130, Method: Compositional matrix adjust.
Identities = 302/900 (33%), Positives = 460/900 (51%), Gaps = 146/900 (16%)
Query: 1958 IRAWRKLIHNLIEMKCLFGPFGDHLCNPDRVFWKLDFMESSARMRQCLRRNYKGSDHFGA 2017
+R W+ + + + C GP+ NP + WKL +E+ +RMR L NY H A
Sbjct: 1772 LRRWKAI---QLYLTCERGPWAKRKQNP--IHWKLANVENYSRMRLKLVPNYNFKTHEEA 1826
Query: 2018 AANFEDHMDMKHDRENVIDPSNAPILAAEAISMGGINEEDEQADIDNLVESEAIDMEQNG 2077
+A D++ ++H + PS+ +L E +Q + ++VE + +D+
Sbjct: 1827 SA-LRDNLGIQHSQ-----PSSDTLLL----------EVVKQVKVSDMVE-DKLDL---- 1865
Query: 2078 KNQPKSSGMAEQPPQASTEYIDTPIANNQDVVQGPSAVAPGYVPSELDERIVLELSSSMV 2137
P + T ++ QD E++VL ++
Sbjct: 1866 ------------PEEDITARVNVDEKEEQDQ----------------KEKLVLMEDCELI 1897
Query: 2138 RPLRVVRGTFQITTRRINFIVDNTECNGDGLDCSSEIRDQEKDRSWLMSSLHQIFSRRYL 2197
+ V+ G +ITT+ I F + E DG+ D W S + +I RRY
Sbjct: 1898 TIIDVIPGRLEITTQHIYFYDGSIE-KEDGVGF---------DFKWPHSQIREIHLRRYN 1947
Query: 2198 LRRSALELFMIDRSNFFFDFGSTEGRRNAYRAIVQARPLQLSNIYLATQRPEQLLKRTQL 2257
LRRSALE+F +D+SN+F +F E R Y ++ L N Y ++ P++L K + L
Sbjct: 1948 LRRSALEIFHVDQSNYFLNF-KKEVRNKIYSRLLS---LHSPNSYYGSRSPQELFKASGL 2003
Query: 2258 MERWARWEISNFEYLMQLNTLAGRSYNDITQYPVFPWILSDYSSKYLDLADPSSYRDLSK 2317
++W EISNF+YL+Q+NT+AGR+YND+ QYPVFPWIL DY+S+ LDL +P+ +RDLSK
Sbjct: 2004 TQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSK 2063
Query: 2318 PVGALNPDRLTKFQERYSSFDDPI--IPKFHYGSHYSSAGTVLYYLTRVEPFTTLSIQLQ 2375
P+G +N +E+Y +F+DP+ I KFHYG+HYS++ V++YL RVEPFTTL IQLQ
Sbjct: 2064 PIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQ 2123
Query: 2376 GGKFDHADRMFSDIGSTWNGVLEDMSDVKELVPELFYLPEILTNENSIDFGTTQLGGKL- 2434
G+FD ADR F I +TW ++++ DVKEL+PE FY PE L N+N + G Q+ +L
Sbjct: 2124 SGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELV 2183
Query: 2435 DSVKLPPWAENPVDFIHKHRMALESEHVSAHLHEWIDLIFGYKQRGKEAILANNVFFYIT 2494
+ V LP WA++ DFI+KHR ALESE+VSAHLHEWIDLIFGYKQRG A+ A NVF+Y +
Sbjct: 2184 NDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCS 2243
Query: 2495 YEGTVDVDKITDPVQQRATQDQIAYFGQTPSQLLTTPHLKKMRLADVLHLQT-------- 2546
YEG VD+D +TD +++A + I FGQTP QLL PH ++ + + T
Sbjct: 2244 YEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLN 2303
Query: 2547 IFRNPKEVKPYAVPNPERCNLPAAAMHASSDSVVIVDINAPAAHLAQHKWQPNTPDGQGM 2606
+F++ E+K + + SD + ++ P K Q + QG
Sbjct: 2304 LFQHLPELKSFFI-------------EGISDGIPLLKATIP-------KNQYRSFMSQGS 2343
Query: 2607 PFLF----------HHGKAIGSSSSGTFMRMFKGPTGSNSDEWHFPRAL--AFATSGIRS 2654
P L HG + + K T +N R++ +FA +
Sbjct: 2344 PELLITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKT---QRSINGSFAPGLEIT 2400
Query: 2655 SAIVSITCD-KEIITGGHVDNSIRLISSDGAKALETARGHCAPVTCLALSPDSNYLVTGS 2713
S + ++ D K + + G+ DNSI+++S K + H VTCLA +L++GS
Sbjct: 2401 SKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGS 2460
Query: 2714 RDTTVLLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLANILADKSRRRRIEGPIHILR 2773
RDTT ++W LA K P IL
Sbjct: 2461 RDTTCMIWQITQQGGVPVG-----------------------LASK--------PFQILY 2489
Query: 2774 GHFKEIVCCCVSSDLGIVVSCSQSSDVLLHSVRKGRLIRRLVGVEAHAICLSSDGIIMTW 2833
GH E++ +S++L + VS S+ V++H+++KG+ +R L ++ L+ + ++W
Sbjct: 2490 GHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISW 2549