Query: CNT0041033
Subject: sp|Q55DM1|LVSA_DICDI BEACH domain-containing protein lvsAOS=Mus musculus GN=Wdfy3 PE=1 SV=1
Score = 588 bits (1515), Expect = e-167, Method: Compositional matrix adjust.
Identities = 330/778 (42%), Positives = 443/778 (56%), Gaps = 71/778 (9%)
Query: 2703 LEHLEKIRFRYNCERVVGLDKHDGIFLIGELCLYVIENFY-IDDHGCICEKECEDELSII 2761
LE EKI+ Y C RV GLD +G+ L G+ E+FY ID +E I
Sbjct: 2512 LEEGEKIQHMYRCARVQGLDTSEGLLLFGK------EHFYVIDGFTMTATRE-------I 2558
Query: 2762 DQAQGLKKQFHGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEKVRVTGNLPHPW 2821
+ L H + + L
Sbjct: 2559 RDIETLPPNMH------------------------------EPIIPRGARQGPSQLKRTC 2588
Query: 2822 HMWKLDSVHEILKRDYELRRVAVEIFSMDGCNDLLVFHKKEREEVFRNLLAMNLPRNSML 2881
++ + + E+ KR Y L+ +AVE+FS DG N LL F K R +V++ LA+ +P +
Sbjct: 2589 SIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAV-VPSLTDS 2647
Query: 2882 DTTISGSAKQESKE-GSRLFKLMA--KSFTKRWQNGEISNFQYLMHLNTLAGRGYSDLTQ 2938
++SG S E GS L + KS T+RW+ GEISNFQYLMHLNTLAGR Y+DL Q
Sbjct: 2648 SESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQ 2707
Query: 2939 YPVFPWILADYDGESLDLSDPNNFRKLDKPMGCQTPEGEEEFRKRYESWDDP--EVPQFH 2996
YPVFPWIL+DYD E +DL++P FR L KPMG QT E +++KRY+ W+DP E P +H
Sbjct: 2708 YPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYH 2767
Query: 2997 YGSHYSSAGIVLFYLIRLPPFSAENQKLQGGQFDHADRLFNSIRETWLSAAGKGNTSDVK 3056
YG+HYSSA IV YL+R+ PF+ +LQGG FD ADR+F+S+RE W SA+ K N +DVK
Sbjct: 2768 YGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSAS-KHNMADVK 2826
Query: 3057 ELIPEFFYMPEFLENRFNLDLGEKQSGDKVGDVILPPWARGSVREFIRKHREALESDYVS 3116
ELIPEFFY+PEFL N N DLG KQ+G K+GDVILPPWA+G REFIR HREALE DYVS
Sbjct: 2827 ELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVS 2886
Query: 3117 ENLHHWIDLIFGHKQRGKAAENAVNVFYHYTYEGNVDVDAVTDPAMKASILAQINHFGQT 3176
+LH WIDLIFG+KQ+G AA AVNVF+H YEG VD+ + DP + + + IN+FGQ
Sbjct: 2887 AHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQI 2946
Query: 3177 PKQLFQKPHVKRRTDRK---------VPPHP------LKHSMHLVPR--NIRKCSSSINQ 3219
PKQLF+KPH +R + VPP H +L P +++ + Q
Sbjct: 2947 PKQLFKKPHPPKRVRSRLNGDNIGISVPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQ 3006
Query: 3220 IITFNDKLLLTGANCLLKPRGYKKYIRWGFPDRTLRFMSYDQDKLLSTHENLHEGNQIQC 3279
I+ + +L N +L P + K WG+ D + R +Y+ DK ++ +E L E QI C
Sbjct: 3007 IVCTDKGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILC 3066
Query: 3280 AGVSHDGRIVVTGAEDGLVSVWRVSKDGPRGSRRLRLEKSLCAHTAKVICLRVSQPYMMI 3339
A V + ++V+TG +V VW + + ++ L L+++L HT V C S Y +I
Sbjct: 3067 A-VCPNPKLVITGGTSTVVCVWEMGTSKEK-AKPLTLKQALLGHTDTVTCATASLAYHII 3124
Query: 3340 ASSSDDCTVIIWDLSSLSFVRQLPNFSVPVTVVYINDLTGEIVTAAGSVLAVWSINGDCL 3399
S S D T IIWDL+ LSF+ QL PV+ + IN+LTG+IV+ AG+ + VWSING+ +
Sbjct: 3125 VSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPI 3184
Query: 3400 SVVNTSQLPTDLIVSVAGSTFSDWLETTWYVTGHQSGALKVWRMVHCTDPVSVPSKTP 3457
VNT + IV S ++W VTGH G ++ WRM P P+ P
Sbjct: 3185 VSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVP-ETPAPEP 3241
Score = 49.3 bits (116), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
Query: 486 PCEQGSG-KVKDLEAVQMLQDIFLKAENKDLQAEVLNRMFKIFTSHLENYRICQELKTVP 544
P G G V++++A +LQ+ FLKA+ L +L+ + I+ + NY I + T+
Sbjct: 369 PQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLS 428
Query: 545 LLVLNMGGFPSSLQELILKILEYAVTVVNCVPEQELLSLCFLLQQPIDSELKHTILSFFV 604
+ P +Q ++LE+ V +N +P +EL+S+ LL+ + +
Sbjct: 429 QFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLL 487
Query: 605 KLTSFDQQYK 614
K T D +K
Sbjct: 488 KFTRHDYIFK 497
Query: CNT0041033
Subject: sp|Q8IZQ1|WDFY3_HUMAN WD repeat and FYVE domain-containing protein 3OS=Dictyostelium discoideum GN=lvsA PE=3 SV=2
Score = 583 bits (1503), Expect = e-166, Method: Compositional matrix adjust.
Identities = 309/737 (41%), Positives = 430/737 (58%), Gaps = 64/737 (8%)
Query: 2819 HPWHMWKLDSVHEILKRDYELRRVAVEIFSMDGCNDLLVFHKKEREEVFRNLLAMNLPRN 2878
H + W + + ++LKR Y LR+VA+EIFS DG N+L+V+ R+E R+ + L N
Sbjct: 2879 HYFLKWAYEDIRDVLKRRYLLRQVALEIFSTDGRNNLVVY----RDEPTRDEVYHTLVNN 2934
Query: 2879 SMLDTTISGSAK-------------------QESKEGSRLFKLMAKS-FTKRWQNGEISN 2918
TI G A+ R + KS T +WQ G+ISN
Sbjct: 2935 VSSHNTIGGDAQGITGGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLKWQQGQISN 2994
Query: 2919 FQYLMHLNTLAGRGYSDLTQYPVFPWILADYDGESLDLSDPNNFRKLDKPMGCQTPEGEE 2978
FQYLMHLNTLAGR Y+DLTQYPVFPW+L+DY+ E LD+ DP +R L KPMG +
Sbjct: 2995 FQYLMHLNTLAGRSYNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPMGALEESRAQ 3054
Query: 2979 EFRKRYESWDDPE-------VPQFHYGSHYSSAGIVLFYLIRLPPFSAENQKLQGGQFDH 3031
+FR+R+E+WDD E VP+FHYG+HYSSA IVL+YLIRL PF+ KLQGG++D
Sbjct: 3055 KFRERFENWDDQEPNEHGHKVPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQ 3114
Query: 3032 ADRLFNSIRETWLSAAGKGNTSDVKELIPEFFYMPEFLENRFNLDLGEKQSGDKVGDVIL 3091
DRLF+SI E W S++ +G+T V ELIPEF+Y+ EFL N + G KQ G+ + D+IL
Sbjct: 3115 PDRLFSSITEAWASSS-QGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIIL 3173
Query: 3092 PPWARGSVREFIRKHREALESDYVSENLHHWIDLIFGHKQRGKAAENAVNVFYHYTYEGN 3151
PPWA+GS +EFI+ HR+ALESDYVSE+LH WIDLIFG++Q+GKAA++++NVFY+ TYEG
Sbjct: 3174 PPWAKGSPQEFIKLHRKALESDYVSEHLHEWIDLIFGYRQQGKAADDSLNVFYYLTYEGA 3233
Query: 3152 VDVDAVTDPAMKASILAQINHFGQTPKQLFQKPHVKRRTDRKVPPHPLKHSMHLVPRNIR 3211
V++DA++DP KA+ +AQIN+FGQTPKQLF KPH KR P ++ L I+
Sbjct: 3234 VNIDAISDPVEKAATIAQINNFGQTPKQLFDKPHPKRNATLMGLPF---YAKALTGNFIK 3290
Query: 3212 KCSSSINQIITFNDKLLLTGANCLLKPRGYKKYIRWGFPDRTLRFMSYDQDKLLSTHENL 3271
+ QI ND+ G N +L P + KY+ WG PD ++R+ + D+ K+L H
Sbjct: 3291 DIGEPVGQIRLINDRATCVGFNKVLLPPNHSKYMLWGLPDGSIRYNTGDKIKVLEDH--- 3347
Query: 3272 HEGNQIQCAGVSHDGRIVVTGAEDGLVSVWRVSKDGPRGSRRLRLEKSLCAHTAKVICLR 3331
H+G + C + DGRI V+G D L+ V+ + +R L K L HT + C+
Sbjct: 3348 HDG-PLTCLTATEDGRICVSGGSDSLICVYNL--------KRFSLAKRLSGHTGSITCVS 3398
Query: 3332 VSQPYMMIASSSDDCTVIIWDLSSLSFVRQLPNFSVPVTVVYINDLTGEIVTAAGSVLAV 3391
S+PY +I S SDD T IIWDL+ L +VR L P++ + I+D TGEIV +G+ ++V
Sbjct: 3399 ASRPYSIIVSGSDDRTCIIWDLNRLCYVRSLDAHEGPISCIGIHDTTGEIVVCSGTTISV 3458
Query: 3392 WSINGDCLSVVNTSQLPTDLIVSVAGSTFSDWLETTWYVTGHQSGALKVWRMVHCTDP-- 3449
+++NG+ L TSQ+ D I S +WL +TGH+ G +KVW + P
Sbjct: 3459 YTVNGELLINYKTSQIANDQITCCIWSKGPEWLGENVLLTGHRDGKVKVWGLETRLLPDN 3518
Query: 3450 -------------VSVPSKTPSNRTGGLNLGNQKPEYXXXXXXXXXXXXQPVTSLHLTTD 3496
+ ++ PS L N +TS+ LT D
Sbjct: 3519 NNSNNNNNNNNNNNNNATQIPSTNNNKLKFKNVI--ILRATFSNSQSHSTAITSIFLTND 3576
Query: 3497 LKQLLSGDSAGHLLSWT 3513
++ +GD G + W+
Sbjct: 3577 QQKFYTGDITGRVCMWS 3593
Score = 72.0 bits (175), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 103/466 (22%), Positives = 175/466 (37%), Gaps = 91/466 (19%)
Query: 2115 VLDFMAEVCADIMTEQIKAVQALESILEMLPLYVDPECVVVFQGLCLSRVMNYXXXXXXX 2174
V+ F+ ++ M + KA+ +E +LE P E +++ L +M
Sbjct: 2129 VVKFLCQIMLSAMRKTSKAISIIEMVLEGAPTTATDEEFILYHSRILLDLMYVVETNITK 2188
Query: 2175 XXXXXXXXXXXXXWSANLDAFCWMIVDRVYMGAFPQPTGVL---RTLEFLLSILQLANKD 2231
+NL M+VDRV + + ++ R F++ IL+ D
Sbjct: 2189 TEFFDNERV-----HSNLIKLSSMLVDRVNLDQLVKNNKIIIAKRIFLFIVKILEKLEAD 2243
Query: 2232 GRVEEVTSSGKGLLSIGRATRQLDAYVHSILKNTNRTILYCFLPSFLITIGEEDLPSRLG 2291
+G L V S+ K+ NR ILY
Sbjct: 2244 --------------RVG-----LQKTVQSLYKSLNRIILY-------------------- 2264
Query: 2292 LLVESTKKQTSKLSGKESGIDVSAVLQLLVANKNIILCPSNLDTDLNCCLCVNLISL-LH 2350
L + D+S V ++ ++ II +NLD+D C L L +
Sbjct: 2265 ------------LINHTTDTDLSFVANHIINHQRIIFSENNLDSDFMNAFCYPLYKLVIS 2312
Query: 2351 DQRKNVQNMASNIIKYLLVHRKSALEDLLVK---------KPHRGQKFDVLHGGFD--RL 2399
DQ ++V N + + + LL + S+ + L R + L GF+ R
Sbjct: 2313 DQHEHVDN-SIKLWRLLLSLKTSSYIESLATVLQLKVSSGSNQRQSEIIDLKPGFELLRN 2371
Query: 2400 LTGNLP----EFSKWLESSEQIITKVLEQGAAVMWIQYIAGSAKFP-DVRMKGMDGRRTR 2454
+GN EF W+ + Q IT+V E+ + + K + + + RRT
Sbjct: 2372 TSGNGAFNNDEFKLWINDNIQTITQVFEENPKKQHLSFKNNEKKHSSEHTLPSLKSRRTE 2431
Query: 2455 EMGRKLRDTSKLDLKHWEQVNER--RYALEVVRDAMSAELRVVR----QNKYGLILHAES 2508
+ +K R K D H E+ ++ + A VR ++ + + K+ I
Sbjct: 2432 RLSKKQRQDRK-DQSHQEEKSKHITKKAQYFVRSESDRRKKIKQLESDKQKFNAI----- 2485
Query: 2509 VWPTHLQQLVHERGIFPMRISHGVEDLKWQLCPIEGPYRMRKKLER 2554
W Q+ ER ++ H ++ KW+L EGPYRMRKK+E+
Sbjct: 2486 QWENMRAQITRERAVWGPSEPHPLD--KWKLDSTEGPYRMRKKMEK 2529
Score = 58.9 bits (141), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 13/194 (6%)
Query: 696 DCMISLLKNSQVNQEAFRSANGVTVILPFLIADEHRTSILRIFSCLITGDIKQVHHEELE 755
D + L+ + N RS + ++L FL R LRI LI D + +E +
Sbjct: 730 DSLFILISENPDNISLIRSFSIFNILLRFLPYSSVRGKSLRILQQLIKYD-PEPTQKEFD 788
Query: 756 ALIDVLKSGMVTRVSGDQYKLHYEVRCDIMGALWRIVGVNGSAQRVFGEATGFSLLLTTL 815
LI VL S K +Y ++ DI+ A ++ ++ A+ F E GF +++
Sbjct: 789 GLIKVLTS---------VNKENYPMKSDILNATRKLFNISKHARDSFREHGGFVSIISVF 839
Query: 816 HTFQGE-EECRDESHL--MVYIKLFKHLLRLITTAVCENAINRMKLHSVITSQTFYDLLV 872
+ + R +S M ++L + + R T+A+C N INR I +TF L+
Sbjct: 840 ISLESSFSPNRKDSRNWDMEKLELIESICRCTTSALCGNVINRENFEQQIGYKTFSSCLI 899
Query: 873 ESGLLCVDLERHVI 886
+G+L + + V+
Sbjct: 900 MTGVLGTEFSKSVV 913
Score = 56.2 bits (134), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 64/120 (53%)
Query: 495 KDLEAVQMLQDIFLKAENKDLQAEVLNRMFKIFTSHLENYRICQELKTVPLLVLNMGGFP 554
K+ A ++L+ FLK+ ++ + ++L+R+ +++S+ N+ + Q T+ +
Sbjct: 498 KNGNAFKVLERYFLKSNYEENRVKILDRILSVYSSNTVNFILLQHTSTLTKFIQEYESLS 557
Query: 555 SSLQELILKILEYAVTVVNCVPEQELLSLCFLLQQPIDSELKHTILSFFVKLTSFDQQYK 614
+ L+ ++KI+ + VTV+NCVP QEL + L+ + I L +F+ +YK
Sbjct: 558 NGLKYHVMKIVCFVVTVLNCVPFQELSTFSLLVGENPSFYTLEMINQLITTLVNFEFRYK 617
Score = 53.5 bits (127), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
Query: 1343 GRLVGNVSLCRQNVIGNSIRPVGGMXXXXXXXXXXXSRDMLHMALSLLACALHQNSQNVK 1402
G L+G+V R+N + +SI+ +GGM S + L +L LL + + N
Sbjct: 1410 GVLIGSVEAFRRNKVADSIKKIGGMPISLLLLEKANSEETLFDSLGLLVGLIQYHPTNTH 1469
Query: 1403 DMETYTGYHLLALFLRPK--MALFDMQCLEIFFQI 1435
+M GY LLA L+ K + LF+ LE+ F +
Sbjct: 1470 EMSQINGYELLAWVLKKKASLGLFNSNILELLFDL 1504
Score = 51.6 bits (122), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 58/272 (21%), Positives = 116/272 (42%), Gaps = 23/272 (8%)
Query: 973 FNKETLTSAGCVELLLEIIYPFLQGSS-PFLSHALKIVEVLGAYRLSPSELKMLCRYVMQ 1031
+N+E L+ + +L L ++ P L +++ +GA LS SEL+ ++V
Sbjct: 974 YNQEALSKLSIPDWILSRFPSNLSNANDPLQPLLLSLIQTVGANCLSGSELR---QFVKL 1030
Query: 1032 MRVMNSGPSLIGMMEKLILMEEDTGLECVSLAPFVEMDMSKTGHASVQVSLGERSWPPAA 1091
++ +S L+ ++ + + P+ E ++SK ++V + ER+WPP
Sbjct: 1031 LQPEHSPEVLLKILSSMA--------KSPPTPPYFEFNLSKIPFGYIRVPITERAWPPTN 1082
Query: 1092 GYSFVCWVQFRNFLTTQELESEVYKAGGSSKTPILSGQQSEQNIF-RIFSVNAISNGSPS 1150
GY+ + W+ F T + + S+ + + + N +I V+ S+ S
Sbjct: 1083 GYTIMFWLYIDKFPTVNNNNNNNNSSNNSNNSNNSNNNNNNNNNNDQIDLVHIYSDDKKS 1142
Query: 1151 YAELYFQEDGIXXXXXXXXXXXXXXXXETE--EGKWHHLAVVHSKPNALAGLFQASVAYV 1208
+Y + +GI + EGKW+H+ +VH++ L + +
Sbjct: 1143 SLYIYLK-NGIITVNIINSSKYVIEIPSYKFVEGKWYHIGIVHAR-----RLLGGTDFKL 1196
Query: 1209 YIDGKLRHMGKLGYSPSPV--GKSLQVIIGTS 1238
++DG L++ P+ + G L IG S
Sbjct: 1197 FVDGFLKYTATKAQYPAQITSGSMLICDIGVS 1228
Query: CNT0041033
Subject: sp|Q6ZS81|WDFY4_HUMAN WD repeat- and FYVE domain-containing protein 4OS=Homo sapiens GN=WDFY3 PE=1 SV=2
Score = 583 bits (1503), Expect = e-166, Method: Compositional matrix adjust.
Identities = 328/781 (41%), Positives = 444/781 (56%), Gaps = 75/781 (9%)
Query: 2703 LEHLEKIRFRYNCERVVGLDKHDGIFLIGELCLYVIENFY-IDDHGCICEKECEDELSII 2761
LE EKI+ Y C RV GLD +G+ L G+ E+FY ID +E I
Sbjct: 2530 LEEGEKIQHMYRCARVQGLDTSEGLLLFGK------EHFYVIDGFTMTATRE-------I 2576
Query: 2762 DQAQGLKKQFHGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEKVRVTGNLPHPW 2821
+ L H + + L
Sbjct: 2577 RDIETLPPNMH------------------------------EPIIPRGARQGPSQLKRTC 2606
Query: 2822 HMWKLDSVHEILKRDYELRRVAVEIFSMDGCNDLLVFHKKEREEVFRNLLAMNLPRNSML 2881
++ + + E+ KR Y L+ +AVE+FS DG N LL F K R +V++ LA+ +P +
Sbjct: 2607 SIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAV-VPSLTDS 2665
Query: 2882 DTTISGSAKQESKE-GSRLFKLMA--KSFTKRWQNGEISNFQYLMHLNTLAGRGYSDLTQ 2938
++SG S E GS L + KS T+RW+ GEISNFQYLMHLNTLAGR Y+DL Q
Sbjct: 2666 SESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQ 2725
Query: 2939 YPVFPWILADYDGESLDLSDPNNFRKLDKPMGCQTPEGEEEFRKRYESWDDP--EVPQFH 2996
YPVFPWILADYD E +DL++P FR L KPMG QT E +++KRY+ W+DP E P +H
Sbjct: 2726 YPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYH 2785
Query: 2997 YGSHYSSAGIVLFYLIRLPPFSAENQKLQGGQFDHADRLFNSIRETWLSAAGKGNTSDVK 3056
YG+HYSSA IV YL+R+ PF+ +LQGG FD ADR+F+S+RE W SA+ K N +DVK
Sbjct: 2786 YGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSAS-KHNMADVK 2844
Query: 3057 ELIPEFFYMPEFLENRFNLDLGEKQSGDKVGDVILPPWARGSVREFIRKHREALESDYVS 3116
ELIPEFFY+PEFL N N DLG KQ+G K+GDVILPPWA+G REFIR HREALE DYVS
Sbjct: 2845 ELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVS 2904
Query: 3117 ENLHHWIDLIFGHKQRGKAAENAVNVFYHYTYEGNVDVDAVTDPAMKASILAQINHFGQT 3176
+LH WIDLIFG+KQ+G AA AVNVF+H YEG VD+ + DP + + + IN+FGQ
Sbjct: 2905 AHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQI 2964
Query: 3177 PKQLFQKPHVKRR------------------TDRKVPPHPLKH-SMHLVPRNIRKCSSSI 3217
PKQLF+KPH +R T K+ H L + L P +++ +
Sbjct: 2965 PKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTP--VKELKEPV 3022
Query: 3218 NQIITFNDKLLLTGANCLLKPRGYKKYIRWGFPDRTLRFMSYDQDKLLSTHENLHEGNQI 3277
QI+ + +L N +L P + K WG+ D + R +Y+ DK ++ +E L E QI
Sbjct: 3023 GQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQI 3082
Query: 3278 QCAGVSHDGRIVVTGAEDGLVSVWRVSKDGPRGSRRLRLEKSLCAHTAKVICLRVSQPYM 3337
CA + + ++V+TG +V VW + + ++ + L+++L HT V C S Y
Sbjct: 3083 LCA-ICPNPKLVITGGTSTVVCVWEMGTSKEK-AKTVTLKQALLGHTDTVTCATASLAYH 3140
Query: 3338 MIASSSDDCTVIIWDLSSLSFVRQLPNFSVPVTVVYINDLTGEIVTAAGSVLAVWSINGD 3397
+I S S D T IIWDL+ LSF+ QL PV+ + IN+LTG+IV+ AG+ + VWSING+
Sbjct: 3141 IIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGN 3200
Query: 3398 CLSVVNTSQLPTDLIVSVAGSTFSDWLETTWYVTGHQSGALKVWRMVHCTDPVSVPSKTP 3457
+ VNT + I+ S ++W VTGH G ++ WRM P P+ P
Sbjct: 3201 PIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVP-ETPAPEP 3259
Query: 3458 S 3458
+
Sbjct: 3260 A 3260
Query: CNT0041033
Subject: sp|Q86JF2|LVSB_DICDI BEACH domain-containing protein lvsBOS=Homo sapiens GN=WDFY4 PE=1 SV=3
Score = 477 bits (1228), Expect = e-133, Method: Compositional matrix adjust.
Identities = 275/728 (37%), Positives = 399/728 (54%), Gaps = 55/728 (7%)
Query: 2829 VHEILKRDYELRRVAVEIFSMDGCNDLLVFHKKEREEVFRNLLAMNLPRNSMLDTTISGS 2888
+ E+ + + L+ +A+EIF +G + LVF+ +R + F++ + ++ G
Sbjct: 2468 MRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQ--------PSLKGK 2519
Query: 2889 AKQESKEGSRLFKLMAKSFTKRWQNGEISNFQYLMHLNTLAGRGYSDLTQYPVFPWILAD 2948
A E R + + ++WQ +ISNF+YLM+LNT AGR +D QYPVFPW+LAD
Sbjct: 2520 ATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLAD 2579
Query: 2949 YDGESLDLSDPNNFRKLDKPMGCQTPEGEEEFRKRYESWDDPE---VPQFHYGSHYSSAG 3005
Y E+L+L++P FR L KPMG QT E + +F +R++ + E Q HY +HYSSA
Sbjct: 2580 YTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAI 2639
Query: 3006 IVLFYLIRLPPFSAENQKLQGGQFDHADRLFNSIRETWLSAAGKGNTSDVKELIPEFFYM 3065
IV YL+R+PPF+ LQGG FD ADR+F+S++ TW SA+ + N SDV+EL PEFFY+
Sbjct: 2640 IVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESAS-RENMSDVRELTPEFFYL 2698
Query: 3066 PEFLENRFNLDLGEKQSGDKVGDVILPPWARGSVREFIRKHREALESDYVSENLHHWIDL 3125
PEFL N ++ G Q G +GDV LPPWA G R+FI HR+ALESD+VS NLHHWIDL
Sbjct: 2699 PEFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDL 2758
Query: 3126 IFGHKQRGKAAENAVNVFYHYTYEGNVDVDAVTDPAMKASILAQINHFGQTPKQLFQKPH 3185
IFG+KQ+G AA +AVN+F+ Y Y +D+ ++TDP +K++IL +++FGQ PKQLF KPH
Sbjct: 2759 IFGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPH 2818
Query: 3186 VKRRTDRK------------VPPHP---------LKHS------MHLVPRNIRKCSSSIN 3218
R K +P HP L+ S M+L +I
Sbjct: 2819 PARTAAGKPLPGKDVSTPVSLPGHPQPFFYSLQSLRPSQVTVKDMYLFSLGSESPKGAIG 2878
Query: 3219 QIITFNDKLLLTGANCLLKPRGYKKYIRWGFPDRTLRFMSYDQDKLLSTHENLHEGNQIQ 3278
I++ +L N +L P + + WGF D + SY DK+L T ENL +
Sbjct: 2879 HIVSTEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGRCL 2938
Query: 3279 CAGVSHDGRIVVTGAEDGLVSVWRVS--KDGPRGSRRLRLEKSLCAHTAKVICLRVSQPY 3336
CA V +VT +V VW +S K PRG LRL ++L HT V CL S +
Sbjct: 2939 CA-VCPSPTTIVTSGTSTVVCVWELSMTKGRPRG---LRLRQALYGHTQAVTCLAASVTF 2994
Query: 3337 MMIASSSDDCTVIIWDLSSLSFVRQLPNFSVPVTVVYINDLTGEIVTAAGSVLAVWSING 3396
++ S S DCT I+WDL L+ V +LP ++ + I+D++G IV+ AG+ L++W++NG
Sbjct: 2995 SLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNG 3054
Query: 3397 DCLSVVNTSQLPTDLIVSVAGSTFSDWLETTWYVTGHQSGALKVWRM--VHCTDP----- 3449
L+ + T+ P I W + +TG Q G ++VW+ V + P
Sbjct: 3055 QPLASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSVPGRPAG 3114
Query: 3450 VSVPSKTPSNRTGGL--NLGNQKPEYXXXXXXXXXXXXQP-VTSLHLTTDLKQLLSGDSA 3506
P++ PS R NL + P VT+L ++ + +LL GD
Sbjct: 3115 EEPPAQPPSPRGHKWEKNLALSRELDVSIALTGKPSKTSPAVTALAVSRNHTKLLVGDER 3174
Query: 3507 GHLLSWTV 3514
G + W+
Sbjct: 3175 GRIFCWSA 3182
Query: CNT0041033
Subject: sp|Q7LKZ7|BPH1_SCHPO Beige protein homolog 1 OS=SchizosaccharomycesOS=Dictyostelium discoideum GN=lvsB PE=3 SV=1
Score = 447 bits (1150), Expect = e-124, Method: Compositional matrix adjust.
Identities = 274/723 (37%), Positives = 385/723 (53%), Gaps = 90/723 (12%)
Query: 2824 WKLDSVHEILKRDYELRRVAVEIFSMDGC---NDLLVFHK-KEREEVFRNLLAMNLPRNS 2879
W D + EI KR + L+ A+EIF G L F+K +R+ V+ +++ LP
Sbjct: 3428 WSYDDIIEIHKRRHVLKNNAIEIFLGSGVPHKTYLFAFNKPSDRDIVYDLIMSKPLPNRV 3487
Query: 2880 MLDTTISGSAKQESKEGSRLFKLMAKSFTKRWQNGEISNFQYLMHLNTLAGRGYSDLTQY 2939
+ G+ ++ S TK+WQ+G ISNF+YLMHLNTLAGR ++DLTQY
Sbjct: 3488 DYAAEVHGN-------------ILKMSITKKWQSGLISNFEYLMHLNTLAGRSFNDLTQY 3534
Query: 2940 PVFPWILADYDGESLDLSDPNNFRKLDKPMGCQTPEGEEEFRKRYESWDDPEVPQFHYGS 2999
P+FP+IL DY+ E LDL +PN FR KPMG Q P+ E+F ++Y + +HYGS
Sbjct: 3535 PIFPFILRDYESEVLDLENPNTFRDFTKPMGAQDPKRLEKFIEKYNDLLEMNEKPYHYGS 3594
Query: 3000 HYSSAGIVLFYLIRLPPFSAENQKLQGGQFDHADRLFNSIRETWLSAAGKGNTSDVKELI 3059
HYS+ G VL +L+RL PF++ QGG+FD DR F+SI ++W ++ N SDVKELI
Sbjct: 3595 HYSNIGSVLHFLVRLQPFTSYFIDFQGGRFDVPDRAFHSIAQSWNLSSSISN-SDVKELI 3653
Query: 3060 PEFFYMPEFLENRFNLDLGEKQSGDKVGDVILPPWARGSVREFIRKHREALESDYVSENL 3119
PEFFY+ +FL N +G KQ+G KV DVILPPWA R FI+KH EALE YVSENL
Sbjct: 3654 PEFFYLSDFLVNSNKFFMGIKQNGVKVDDVILPPWAHNDPRLFIKKHNEALECKYVSENL 3713
Query: 3120 HHWIDLIFGHKQRGKAAENAVNVFYHYTYEGNVDVDAVTDPAMKASILAQINHFGQTPKQ 3179
HHWIDL+FG+KQ+G+AA A N+F+ TYEG VD+D++ D + + +AQI+ +GQTPKQ
Sbjct: 3714 HHWIDLLFGYKQQGEAAVKAHNMFFPLTYEGAVDIDSIEDQLNRDAAVAQIHSYGQTPKQ 3773
Query: 3180 LFQKPHVKR---RTDRKVPPHPLKHSMHLVPRNIRKCSSSINQIITFNDK--LLLTGANC 3234
+F KPH K+ +T R L + + S I I ND + LT
Sbjct: 3774 IFTKPHPKKNWSKTIRLTQDSIFTKPERLTSYIMFQYRSPIGSITIANDSSPIHLTPQRI 3833
Query: 3235 LLKPRGYKKYIRWGFPDRTLRFMSYDQDKLLSTHENLHEGNQIQCAGVSHDGRIVVTGAE 3294
L P K I WG D+ LR S D K+LS E L++ I C ++ +GR+ VTG
Sbjct: 3834 LFFPDN-NKSISWGHWDQNLRVNSIDTGKVLSIIEVLND--DIICGDITKNGRLFVTGGT 3890
Query: 3295 DGLVSVW-RVSKDGPRGSRR-----LRLEKSLCAHTAKVICLRVSQPYMMIASSSDDCTV 3348
G V VW R + DG +R+ L L +L HT ++C+ VSQ Y +I S S D
Sbjct: 3891 AGTVKVWKRCNNDGTIMTRKERGDNLSLWSTLYGHTNSILCVTVSQEYSIIVSGSKDSNC 3950
Query: 3349 IIWDLSSLSFVRQLPNFSVPVTVVYINDLTGEIVTAAGSV-------------------- 3388
IIWDL+ L+++ L + PVT V ++ G I T ++
Sbjct: 3951 IIWDLNRLTYINSLQH-DHPVTCVQVSPTFGYIATFETNIYNKQNNNSGGGGSKNDNSIN 4009
Query: 3389 ----LAVWSINGDCLSVVNTSQLPTDLIVSVAGSTFSDWLETTWYVTGHQSGALKVWRMV 3444
L +WSING L+ N D + + ++ + T +TG +SG + +W
Sbjct: 4010 GSGCLRLWSINGTLLAKQN---FVNDRVNCMIFTSTIQGVNTNLLITGMESGTIILWNAW 4066
Query: 3445 HCTDPVSVPSKTPSNRTGGLNLGNQKPEYXXXXXXXXXXXXQPVTSLHLTTDLKQLLSGD 3504
+ ++ SK+ +T+L ++ D QL+SGD
Sbjct: 4067 NLQKIRTLVSKS------------------------------TITALAVSKDNTQLISGD 4096
Query: 3505 SAG 3507
G
Sbjct: 4097 ING 4099