Score =  862 bits (2227), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 743/2902 (25%), Positives = 1291/2902 (44%), Gaps = 349/2902 (12%)

Query: 475  EVNDCKNLIKTLVMGMKTIIWSITHAHLPRPQGMNPQALVSQSSAPQGFK----GMREDE 530
            +V DC++L+KTLV G+KTI W IT    P      P   +         K     M+  +
Sbjct: 542  QVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQALD 601

Query: 531  VWK----ASGVLKSGVHCLALFKEKDEEKEMLNLFSQILAIMEPRDLMDMFSLCMPELFE 586
            +++     +G     V      + K EEKE+L  F+ +  +M P    ++F   +P + E
Sbjct: 602  IYQVQIAGNGQTYIRVANCQTVRMK-EEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVE 660

Query: 587  SMINNNQLVQIFAALLQAPKVYKPFADVLINLLVSSKLDVLKNPDSAATKLVLHLFRCIF 646
             +  N  L  +  + L  P     FA +L+  L+    ++  N +   + L L LF+ +F
Sbjct: 661  RISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVE--LSNLYLKLFKLVF 718

Query: 647  GAVTKTPSDFERILQHHVPVIMEVCMKNATEVEKPLGYMQLLRTVFRGLAGCKYEXXXXX 706
            G+V+   ++ E++L+ H+  I+   M+ A   ++P  Y  LLR +FR + G  ++     
Sbjct: 719  GSVSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQE 778

Query: 707  XXXXXXXXXNILLTMLEGPAGEDMKDLLLELCLTXXXXXXXXXXXXXXXMKPLVFCLRGS 766
                       L  +  G   + MKDL +ELCLT               M PLV  L GS
Sbjct: 779  FLPLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGS 838

Query: 767  DELVSLGLRTLEFWVDSLNPDFLEPSMANVMSEVILALWSHLRPVPYPWGKKALQILGKL 826
              LVS GLRTLE  VD+L PDFL   +  V +E++ ALW  LR         A ++LGK 
Sbjct: 839  QTLVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKF 898

Query: 827  GGRNRRFLKEPLTLECKDNPEHGLRLVLTFEPSTPFL-VPLDKFINLAVAAVIQRNHGMD 885
            GG NR+ LKE   L        G  + + F      L +P++K I  A+  +   N   +
Sbjct: 899  GGSNRKMLKESQKLHYVVTEVQGPSITVEFSDCKASLQLPMEKAIETALDCLKSAN--TE 956

Query: 886  IYYRKQA---LKFLRVCLLSQLNLPGCVTDVGQTPRQLSTLLRSSVDSSWHRSEAVEIKA 942
             YYR+QA   +K   V ++S  +    +  +   P      + + + S  HR +A +  A
Sbjct: 957  PYYRRQAWEVIKCFLVAMMSLEDNKHALYQLLAHPNFTEKTIPNVIIS--HRYKAQDTPA 1014

Query: 943  DLGVKTKTQLMAEKSIFKTLLITILAAXXXXXXXXXXXXFVENICRHFAIILHVDYXXXX 1002
                         +  F+  L     +            FV ++ RH+ ++         
Sbjct: 1015 -------------RKTFEQALTGAFMSAVIKDLRPSALPFVASLIRHYTMVA----VAQQ 1057

Query: 1003 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPLIFLDALVDVLADENRLHAKAALNALNV 1062
                                          DPL+ +DA+   +A E +   K    AL V
Sbjct: 1058 CGPFLLPCYQVGSQPSTAMFHSEENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAV 1117

Query: 1063 FAETLLFLARVKHADVLMARGGHNASMIVSSPSTNPVYSPHPSVRIPVFEQLLPRLLHGC 1122
              +                     AS+I+ S           + ++P+F  ++ RL   C
Sbjct: 1118 IFDV--------------------ASIILGSKER--------ACQLPLFSYIVERLCACC 1149

Query: 1123 YGSTWXXXXXXXXXXXXXXXKVNVETLCYFQVKIVRGLVYVLKRLPVYASKEQEETSQVL 1182
            Y   W               ++ +  +   Q   ++ L++V+  L    S      ++  
Sbjct: 1150 YEQAWYAKLGGVVSIKFLMERLPLTWVLQNQQTFLKALLFVMMDLTGEVSNGAVAMAKTT 1209

Query: 1183 MQ--ILRVVNNV-DEANSE----ARRKSFQDVVEYLATELFNPNASIPVRKNVQNCLALL 1235
            ++  ++R    + DE  +E    A+ KSF  V   L  E+ +PN++  VRK   + L +L
Sbjct: 1210 LEQLLMRCATPLKDEERAEEIVAAQEKSFHHVTHDLVREVTSPNST--VRKQAMHSLQVL 1267

Query: 1236 ASRTGSEVTXXXXXXXXXXXXXXIMRP-----LRSKTVDQQVGTVAALNFCLALRPPLLK 1290
            A  TG  VT               M P     LR +  + Q+G +    FC  L+P L  
Sbjct: 1268 AQVTGKSVTVIMEPHKEVLQD---MVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFT 1324

Query: 1291 VTPELVN---FLQEALQIAEADETVWAVKLMNPKVLTSLNRLRTACIELLCTTMAWTDFR 1347
            +   +V    F  E L + EA+++    KL   K L SL  LR A +      +A  ++ 
Sbjct: 1325 MDLNVVEHKVFYTELLNLCEAEDSAL-TKLPCYKSLPSLVPLRIAAL----NALAACNYL 1379

Query: 1348 TQTHNELRAKIISMFFKSLTCRAPEIVAVAKEGLRQVINQQRMPKELLQSSLRPILVNLA 1407
             Q+    R KII+  FK+L     E+    +  +R+ +    +  + + + +RP+L+ L 
Sbjct: 1380 PQS----REKIIAALFKALNSTNSELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLG 1435

Query: 1408 HTKNLSMPXXXXXXXXXXXXSNWFNVTLGGKLLEHLKKWLEPEKLAQSQKAWKAG----- 1462
              ++L++              N FN     ++++HL+KW+E   +         G     
Sbjct: 1436 DYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNESIS 1495

Query: 1463 -------------EEPKIAAAIIELFHLLPHAASKFLDELVTLTIDLEAALPPGQVYSEI 1509
                         EE KI +AII LFHL+P A    +  L+ + +  E A+       E 
Sbjct: 1496 ECGRCPLSPFCQFEEMKICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAM-----LIEA 1550

Query: 1510 NSPYRLPLTKFLNRYAALAVDYFL--SRLSEPKYFRRFMYIIRSDAGQPLREELAKSPQK 1567
             SP+R PL KFL R+ +  V+ F+  + L++P++ R FM  ++    +PLR+ LA +P +
Sbjct: 1551 GSPFREPLIKFLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDARPLRDVLAANPNR 1610

Query: 1568 ILSYAFPEISPKXXXXXXXXXXXXXXXXXGDENHISVKLESSNVASTKANIASDAYFQGL 1627
             ++   P                            +V+  S + ++ +     D  FQ +
Sbjct: 1611 FITLLLP-----------------------GGAQTAVRPGSPSTSTMRL----DLQFQAI 1643

Query: 1628 YLIKTMVKLIPSWLQSNRSVFDTLVLIWKSPARISRLQNEQELNLVQVKESKWLVKCFLN 1687
             +I  +VK   SWL S  S+   L  +W S     R + E  +     KE K L  C LN
Sbjct: 1644 KIISIIVKNDDSWLASQHSLVSQLRRVWVSENFQERHRKEN-MAATNWKEPKLLAYCLLN 1702

Query: 1688 YLRHEKSEVNVLFDILSIFLFHSRIDYTFLKEFYIIEVAEGYPPNMKRALLLHFLNLFHS 1747
            Y +    ++ +LF +L  F      + TFLKE+   E+ + Y    KRAL   F++ F+ 
Sbjct: 1703 YCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFVD-FND 1761

Query: 1748 KQLGHDHLVQAMQMLILPMLAHAFQNGQTWEVIDP---------DIVKTIVERLLDPPEE 1798
               G +   + +Q ++ P   ++F+ G+  +++ P          I    + ++LDP ++
Sbjct: 1762 PNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDPEKQ 1821

Query: 1799 VSA---------EYDEPXXXXXXXXXXXXXXXXQSDLVHHRKELIKFGWNHLKRE---DS 1846
                        +Y                    S L    + L+ F W  L  +   D 
Sbjct: 1822 ADMLDSLRIYLLQYATLLVEHAPHHIHDNNKNRNSKL----RRLMTFAWPCLLSKACVDP 1877

Query: 1847 ASKQWAFVNVCHFLDAYQAPEKIILQVFVALLRTCQPENKMLVKQALDILMPALPKRLPL 1906
            A K    + + H +  +   +KI+LQVF +LL+    E + +V+QA+ IL PA+P R+  
Sbjct: 1878 ACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMED 1937

Query: 1907 GDSRMPIWIRYTKKILVEEGHSIPNLIHIFLLVVRHSDLFYSCRAQFVPQMVNSLSRLGL 1966
            G   +  W   T+KI+VEEGH++P L+HI  L+V+H  ++Y  R   V  MV+++ RLG 
Sbjct: 1938 GHQMLTHW---TRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGF 1994

Query: 1967 PYNTTAENRRLAIELAGLVVSWERQRQNEMKMVTDTDGTSQITDEMHTSSGADPKRSTDG 2026
              + T E RRLA++L+ +V+ WE QR  + +  +D D  S  + E   S  +  KR    
Sbjct: 1995 TPSVTIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNS--SGEGVNSVSSSIKRGL-- 2050

Query: 2027 SATSEDPSKRVKIEPGLQSICVMSPGGASSIPNVETPGSATQPDEEFKP-NAAMEEMIIN 2085
            S  S    KR +   G  S      G + S+P  ++  +        KP +    + ++N
Sbjct: 2051 SVDSAQEVKRFRTATGAISAVF---GRSQSLPGADSLLA--------KPIDKQHTDTVVN 2099

Query: 2086 FLIRVALVIEPKDRETNT-------MYKQALDLLSQAL--EVWPSANVKFNYLEKLLSSM 2136
            FLIRVA  +   +  TNT       + ++ ++LL  AL  ++WP + +K  + +KLL ++
Sbjct: 2100 FLIRVACQV---NDNTNTAGSPGEVLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTV 2156

Query: 2137 PPSQSDPSTALAQGLDVMNKVLEKQPHLFIRNNINQISQILEPCFKHKMLDAGKSLCSLL 2196
                      +  GL+V++ +L       I ++   + + +  C         +++ SLL
Sbjct: 2157 EQPNQVNYGNICTGLEVLSFLLTVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLL 2216

Query: 2197 KMVFTAFPLD-----AANTPPDIKLLYQKVNELINKHVNTVTAPQTSGDDNSFGSISFVL 2251
              + + FP +      A+   +++ LY  V ++I + +        +     FG+    L
Sbjct: 2217 SRLMSIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATNANPSQLFGT----L 2272

Query: 2252 LVIKTLANVHKNFVDSYVLVRILQRLARDLGSAVGSHPRQGQRTDSDSAVTSSRQTADVG 2311
            +++K+  + + +++D     R++    R L   V  H      + S  A + + +   + 
Sbjct: 2273 MILKSACSNNPSYID-----RLISVFMRSLQKMVREHLNPQAASGSTEATSGTSELVMLS 2327

Query: 2312 AVICNIKSVLELIDETVMLIA-DCKRSVTQILNTLLSEKGTDASVLLCILDMIKRWVEDD 2370
                     LEL+   + +++ + +++  Q + T L EK  DA +L  ++ +++ WV+++
Sbjct: 2328 ---------LELVKTRLAVMSMEMRKNFIQAILTSLIEKSPDAKILRAVVKIVEEWVKNN 2378

Query: 2371 FSKTGASGLSGSFLTQKDVLTFLNKLSYIDKQHFSSEALEEWDQKYLQLLYGLCADSTKY 2430
               +  +      L +K +L  +  ++YI+K+ F  +   E + ++L L+  +  D T  
Sbjct: 2379 ---SPMAANQTPTLREKSIL-LVKMMTYIEKR-FPEDL--ELNAQFLDLVNYVYRDETLS 2431

Query: 2431 PLGLRQEVSLKVERHFMLGLRASHPGMRRKFFLLYHESLGKTLFARLQYIIQIQDWEALS 2490
                  E++ K+E  F+ GLR + P +R KFF ++  S+ + ++ RL Y+   Q+WEA+ 
Sbjct: 2432 G----SELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMG 2487

Query: 2491 DVFWLKQGLDLLLAILVEDKPI------SLAPNSARVLPLLPSDN--------------- 2529
            + FW+KQ ++LLLA+  +  PI      ++ P+   V+ L  S +               
Sbjct: 2488 NHFWIKQCIELLLAVCEKSTPIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPR 2547

Query: 2530 -------------------PGIQHQAPANLEGPE-EVTSMFDSIVMKHAQFLSATSKLQV 2569
                               PG Q   P   E  E ++ +    +  +H +FL    +++ 
Sbjct: 2548 ERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDTLREVKT 2607

Query: 2570 ADVVIPLRELAHTDANVAYHLWVLVFPIVWVTLLKEEQVALAKPMISLLSKDYHKKQQGH 2629
              ++    +L H    +A   WV +FP +W  L   +Q ALA  +   L    H+ Q+  
Sbjct: 2608 GALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCSGSHQVQRDC 2667

Query: 2630 RPNVVQALLEGL-QLSHPQPRMPSELIKYIGKTYNAWHLALALLESHVM----------- 2677
            +P+ +   +E + Q   P P  P  ++KY+GKT+N W  +  +LE               
Sbjct: 2668 QPSALNCFVEAMSQCVPPIPIRPC-VLKYLGKTHNLWFRSTLMLEHQAFEKGLSLQIKPK 2726

Query: 2678 ----LFMNDS------KCAESLAELYRLLNEEDMRFGLWKKRSITAETRAGLSLVQHGFW 2727
                 +  +S      +  +SLAELY LL EEDM  GLW+KR   +ET   ++  QHGF+
Sbjct: 2727 QTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKYSETATAIAYEQHGFF 2786

Query: 2728 QRAQSLFYQAMVKATQGTYNNTVPKA---EMCLWEEQWLHCASQLSQWDALVDFGKS--- 2781
            ++AQ  + +AM KA +    +    A   E  LWE+ W+ C+ +L+QW+AL ++G+S   
Sbjct: 2787 EQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALTEYGQSKGH 2846

Query: 2782 IENYEILLDSLWKLPDWAYLKDHVIPKAQVEETP------KLRLVQSYFALHDRNSNGVG 2835
            I  Y ++L+  W++ +W  +K+ ++   QVE +       K+ + + Y A+       + 
Sbjct: 2847 INPY-LVLECAWRVSNWTAMKEALV---QVEVSCPKEMAWKVNMYRGYLAICHPEEQQLS 2902

Query: 2836 DAENTVGKGVDLALEQWWQLPEMSVHARVPXXXXXXXXXXXXXSARIHVDIANGNKVSGN 2895
              E  V     LA+ +W +LP +  H   P             +A+I+  +   N     
Sbjct: 2903 FIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNL---- 2958

Query: 2896 TAVGGLGNRYADLKDILETWRLRTPNEWDNMTVWYDMLQWRNEMY-----------NVVI 2944
                G  N   D+K +++TWR R P   D+++ W  +  WR   Y           + ++
Sbjct: 2959 ----GRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQGKPTWSGMHSSSIV 3014

Query: 2945 DAFKDFA----TSNSPLHHLGFRDKAWNVNKLARIARKQGLYDVCVQILEKMYGHSTMEV 3000
             A+++ +    +SN+ +  LG    A  + +  +IARKQGL +V + IL +++   T+ +
Sbjct: 3015 TAYENSSQHDPSSNNAM--LGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPI 3072

Query: 3001 QEAFVKIREQAKAYLEMKG-----ERASGLNLINSTNLEYFPDKIKAEIFRLKGDFHLKL 3055
             + F KIR+Q K YL++ G     E   GL +I STNL+YF  ++ AE + LKG F  ++
Sbjct: 3073 VDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQI 3132

Query: 3056 NDTESANIAYSNAITLFKNLPKGWISWGSYCDMAYQETQEEIWLEYAVSCFLQGIRF-GV 3114
            N +E AN A+S A+ +   L K W  WG Y +  + + ++      A++C+L   R    
Sbjct: 3133 NKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNE 3192

Query: 3115 SNSRSHIARVLYLLSFDTANEPVGRVFDKHLDQVPHWVWLSWIPQLLLSLQRTEAPHCKL 3174
            S SR ++A+VL+LLSFD     +    DK+   VP   WL+WIPQLL  L  +E      
Sbjct: 3193 SKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLN 3252

Query: 3175 VLLKIAAVFPQALYYWLRTYLL 3196
            ++ ++  V+PQA+Y+ +RT  L
Sbjct: 3253 LISQVGRVYPQAVYFPIRTLYL 3274



 Score =  261 bits (666), Expect = 8e-68,   Method: Compositional matrix adjust.
 Identities = 157/457 (34%), Positives = 259/457 (56%), Gaps = 39/457 (8%)

Query: 4   IQNFEQHSRRLVDLDLPIPTRLEMVVEVRDSLE-IAHTAEYLNFLKCYFPAFSVILLQIT 62
           ++ + Q    L D++ P  T+L+M+ EV ++ E +  + +Y  FL+   P F +  LQ  
Sbjct: 18  MKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRF-LTFLQDG 76

Query: 63  KPQFI-DNPEHKLRNIVVEILNRLPHSEVLRPFVQDLLKVAMQVLTADNEENGLICIRII 121
           + QF+ + P  +LR +V+EI++R+P +E LRP  +++L V  + L  +NEEN LIC+RII
Sbjct: 77  EVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRPHTKNVLSVMFRFLETENEENVLICLRII 136

Query: 122 FDLLRNFRPTLENEVQPFLDFVCKIYSIFRFTVSHFFDNVKMEEVKPMEMPTSSDQSLTP 181
            +L + FRP +  E+  FLDFV +IY      V+ +F+N       P  +P   + ++ P
Sbjct: 137 IELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFEN-------PQVIP---ENTVPP 186

Query: 182 TPPIG-----NVQLNPS-----TR----------SFKIITESPLVVMFLFQLYSRLVQTN 221
              +G      V++NP      TR          S K++ E P++V+ ++QLY   +   
Sbjct: 187 PEMVGMITTIAVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNV 246

Query: 222 IPHLLPLMVAAISVPGPENVPSHL---KPQFIELKGAQVKTVSFLTYLLKSCAEYIRPHE 278
           +   +PL++  I++        H    K  + +   AQ+KT+SFL Y+++   E +  + 
Sbjct: 247 VAEFVPLIMNTIAIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQELVTKYS 306

Query: 279 ESICKSIVNLLVTC-SDSASIRKELLVSLKHVLGTDFKRGLFPLIDTLLDERVLVGTGRA 337
           + + K ++ LL  C +++A +RKELL++ KH+L T+ +    P +D L DE +L+G+G  
Sbjct: 307 QQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTELRNQFIPCMDKLFDESILIGSGYT 366

Query: 338 CFESLRPLAYSLLAEIVHHVRGDLSLAQLSRIIYLFSRNMHDSTLSLSIHTTCARLMLNL 397
             E+LRPLAYS LA++VHHVR  L L+ LS  + LF++N+ D +L  SI T   +L+LNL
Sbjct: 367 ARETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESLPSSIQTMSCKLLLNL 426

Query: 398 VEPIFEKGVDQQSMDEARILLGRILDAFVGKFSTFKR 434
           V+ I  K   +Q     R +L R+L+ FV KF T  R
Sbjct: 427 VDCIRSKS--EQESGNGRDVLMRMLEVFVLKFHTIAR 461



 Score =  209 bits (532), Expect = 3e-52,   Method: Compositional matrix adjust.
 Identities = 135/452 (29%), Positives = 230/452 (50%), Gaps = 38/452 (8%)

Query: 3419 LAELTARLKKWKNILQSNVEDRFPAVLRLEDESRVLRDFN--VVDVEIPGQYFADQEVAP 3476
            L  L ++LKKW  IL++  + + P    +E++ R L +F+    +VEIPG++   +   P
Sbjct: 3434 LHNLISKLKKWIKILEAKTK-QLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPK---P 3489

Query: 3477 DHT-VKLDRVGADVPIVRRHGSSFRRLTLIGSDGS-QKHFIVQTSLTPNARSDERILQLF 3534
             H  +K+ R    V IV++H ++ RRL + G +G    + ++  +    +R +ER+LQL 
Sbjct: 3490 THYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLL 3549

Query: 3535 RVMNQMFDKHKESRRRHIGIHTPIIIPVWSQVRMVEDDLMYNTFLEVYENHCARNDREAD 3594
            R++N   +K KE+ +RH+    P ++ V  Q+R+VED+    + +E+Y+  CA+   E D
Sbjct: 3550 RLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHD 3609

Query: 3595 LPITHFKEQLN--QAISGQISAEAIGDLRLQAYIDITKTLVNDSIFSQYMYKTLMSGSHM 3652
             PI+ + ++L   QA   Q S + + D+      ++   +V  S+  ++   T  + +  
Sbjct: 3610 NPISRYYDRLATVQARGTQASHQVLRDI----LKEVQSNMVPRSMLKEWALHTFPNATDY 3665

Query: 3653 WAFKKQFAVQLAVSSFMSFMLQIGGRSPNKVLFAKNTGKM----FQTDFHPAYDANGMIE 3708
            W F+K F +QLA+  F  F+L +   +P  +  A++TGK+    F+ D +   DA G ++
Sbjct: 3666 WTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDIN---DATGDLD 3722

Query: 3709 FNEPVPFRLTRNMQAFFSQFGVEGLLMSSMCSAAQAVISSKQNEHLRYQLAMFFRDELLS 3768
             N PVPFRLT N+  F +  GV G L +SM + A+    ++ N  +   L    RDE+++
Sbjct: 3723 ANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCF--AQPNFKVDGILKTVLRDEIIA 3780

Query: 3769 WFXXXXXXXXX--XXXXXXATLNPAELKHKVNANVEDVIKRIRGIAPQYFSEEDENTVEP 3826
            W                    ++  +L   V   V  ++ R+  +A Q+   E +     
Sbjct: 3781 WHKKTQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLA-QFEGGESK----- 3834

Query: 3827 PQSVQRGVNELVEAALSPRNLCMMDPTWHPWF 3858
                   VN LV AA S  NLC MDP WHPW 
Sbjct: 3835 -------VNTLVAAANSLDNLCRMDPAWHPWL 3859

 Score =  770 bits (1989), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 716/2987 (23%), Positives = 1299/2987 (43%), Gaps = 444/2987 (14%)

Query: 1033 DPLIFLDALVDVLADENRLHAKAALNALNVFAETLLFLARVKHADVLMARGGHNASMIVS 1092
            DP+I +DAL   +  E +   K  +  + +  +T                          
Sbjct: 1100 DPMILIDALASCMGHEEKELCKPGIACMGIILDT-------------------------- 1133

Query: 1093 SPSTNPVYSPHPSVRIPVFEQLLPRLLHGCYGSTWXXXXXXXXXXXXXXXKVNVETLCYF 1152
              +TN + +   + ++P+ + L  +++  CY   W                +++  L   
Sbjct: 1134 --ATNIMGNKDRACKLPIIQYLAEKMVSLCYDRPWYSKVGGCQAIQFLCKHMSLRALFQN 1191

Query: 1153 QVKIVRGLVYVLKRLPVYASKEQEETSQVLMQ---------ILRVVNNVDEANSEARRKS 1203
                ++  ++VL  L    S    E ++  M+         I     N+D  + +A  K+
Sbjct: 1192 LFNFLKAFMFVLMDLEGDVSNGAIEITKSYMKSMLEICLTPINECYKNIDLKDLQA--KA 1249

Query: 1204 FQDVVEYLATELFNPNASIPVRKNVQ-NCLALLASRTGSEVTXXXXXXXXXXXXXXIMRP 1262
              +V+  L   + +PN  +     V    +  + S+T SEV               I+ P
Sbjct: 1250 TYEVIHELVRHITSPNTIVREESMVLLKHIGTIQSKTVSEV-----MDPHKDVLADIIPP 1304

Query: 1263 ----LRSKTVDQQVGTVAALNFCLALRPPLLKVTPELVN-----FLQEALQIAEADETVW 1313
                LR +  + Q+G +    FC  L P L   T +L N     F  E L ++EA++   
Sbjct: 1305 KKHLLRHQPANAQIGLMDGNTFCTTLEPRLF--TIDLTNTYHKLFFHELLTLSEAEDATL 1362

Query: 1314 AVKLMNPKVLTSLNRLRTACIELLCTTMAWTDFRTQTHNELRAKIISMFFKSLTCRAPEI 1373
            A KL   K + +L  LRT+ +  L      +D         + KII++ FK +     E+
Sbjct: 1363 A-KLDCYKNVPNLIPLRTSALRALAACHYISDI------GYKEKIINIIFKVMESDKSEL 1415

Query: 1374 VAVAKEGLRQVINQQRMPKELLQSSLRPILVNLAHTKNLSMPXXXXXXXXXXXXSNWFNV 1433
               A   ++  I    + KE +QS++RP+L+ L   +NLS+P               FN 
Sbjct: 1416 QTTAFHCMKHFITGVTLEKEKVQSAMRPLLLKLGDHRNLSIPAIKRLSYFTQIFPQMFNE 1475

Query: 1434 TLGGKLLEHLKKWLE---PEKLAQSQK-----AWKAGEEPKIAAAIIELFHLLPHAASKF 1485
             L  ++L+H  K +E    E  + S       + K GE  +    +IE+F  +  A+ K+
Sbjct: 1476 KLSEQILQHCSKIMEIFVSEYKSTSPNVNFFASSKGGEYEQKIVILIEMFFYIS-ASVKY 1534

Query: 1486 LDELVTLTIDLEAALPPGQVYSEINSPYRLPLTKFLNRYAALAVDYFL--SRLSEPKYFR 1543
            +++L  L +  E  L       E +SPYR  L KFL R+    VD FL  S + +P++ R
Sbjct: 1535 IEKLCQLVLKTEKNL-----MIEASSPYREALIKFLQRFPTETVDLFLTESLMIDPQWNR 1589

Query: 1544 RFMYIIRSDAGQPLREELAKSPQKILSY------AFPEISPKXXXXXXXXXXXXXXXXXG 1597
             F+Y+++ + G   R  +  S    L +       FPE                      
Sbjct: 1590 LFIYLLKHETGVSFRAVIKSSRYNNLIHYLNTHTEFPE---------------------- 1627

Query: 1598 DENHISVKLESSNVASTKANIASDAYFQGLYLIKTMVKLIPSWLQSNRSVFDTLVLIWKS 1657
                 ++K E  +              Q + +I T+++    W+ + + + D L   W++
Sbjct: 1628 -----ALKYEIQH--------------QAVLIIFTLMESDDQWIPTRQDIVDALKNCWQN 1668

Query: 1658 PARISRLQNEQELNLVQVKESKW--LVKCFLNYLRHEKSEVNVLFDILSIFLFHSRIDYT 1715
               +S L +E  L         W  + K  L+Y  +  +++ +LF +L    F    D  
Sbjct: 1669 --YLSTLSSEDVLC------DLWHLIGKILLHYFSNNTNDIELLFQLLRALCFRFIPDVY 1720

Query: 1716 FLKEFYIIEVAEGYPPNMKRALLLHFLNLFHSKQLGHDHLVQAMQMLILPMLAHAFQNGQ 1775
            FL++F    VA+ +  N KR    +F+  F++  L  +   + +  +I+P  A +F  G+
Sbjct: 1721 FLRDFLQHTVAQSFTVNWKRNAFFYFVENFNNSFLSEELKAKIITAVIIPCFAVSFDKGE 1780

Query: 1776 TWEVI----------DPDIVKTIVERLLDPPEEVSAEYDEPXXXXXXXXX-----XXXXX 1820
              ++I          + +IV   + ++ DP ++    YD+                    
Sbjct: 1781 GNKLIGAPPTPYQEDEKNIVSVFINKVFDPDKQ----YDDAVRIALLQLACLLVERASQH 1836

Query: 1821 XXQSDLVHHR-----KELIKFGWNHLKRE---DSASKQWAFVNVCHFLDAYQAPEKIILQ 1872
                D  + R     + L+ F W  L  +   D  ++    + + H +      +KI+LQ
Sbjct: 1837 IHDGDANNKRQGNKLRRLMTFAWPCLLSKSSVDPTARYHGHLLLSHIIARLAIHKKIVLQ 1896

Query: 1873 VFVALLRTCQPENKMLVKQALDILMPALPKRLPLGDSRMPIWIRYTKKILVEEGHSIPNL 1932
            VF +LL+    E + +VKQALD+L PA+P R+  G++ +  W   TKKI+VEEGH++  L
Sbjct: 1897 VFHSLLKGHALEARSIVKQALDVLTPAMPLRMEDGNTMLTHW---TKKIIVEEGHAMQQL 1953

Query: 1933 IHIFLLVVRHSDLFYSCRAQFVPQMVNSLSRLGLPYNTTAENRRLAIELAGLVVSWERQR 1992
             HI  L++RH  +++  R Q V  ++N + RLG P   + E+++LA++LA +++ WE  R
Sbjct: 1954 FHILQLIIRHYKVYFPVRHQLVQHLINYMQRLGFPPTASIEHKKLAVDLAEVIIKWELHR 2013

Query: 1993 QNEMKMVTDTDGTSQITDEMHTSSGADPKRSTDGSATSEDPSKRVKIEPGLQSICVMSPG 2052
              + +  T TDGT +   E+   S    KRS      +   S  +  E  +Q  CVM   
Sbjct: 2014 IKDDRE-TKTDGTEE---ELIQESSV--KRSGIDLVETRKKSFDIIRETTVQGKCVM--- 2064

Query: 2053 GASSIPNVETPGSATQPDEEFKPNAAMEEMIINFLIRVALVIEPKDRETNTMYKQALDLL 2112
                                              L+++A+  E        ++ Q  D+ 
Sbjct: 2065 ----------------------------------LLKMAMRPE--------IWPQPFDI- 2081

Query: 2113 SQALEVWPSANVKFNYLEKLLSSMPPSQSDPSTALAQGLDVMNKVLEKQPHLFIRNNINQ 2172
                        K N+L+K+L+++     + +  +  G+D +  +        + + I  
Sbjct: 2082 ------------KLNWLDKVLATVETPHHNLNN-ICTGIDFLTFLTTILSPDQLVSIIRP 2128

Query: 2173 ISQILEPCFKHKMLDAGKSLCSLLKMVFTAFPLDAANTPPDIKLLYQKVNELINKHVNTV 2232
            + + L  C  H+     + +   L  +   FP D  +   D+ LLY  V+++I +++ + 
Sbjct: 2129 VQRGLSLCIIHQNTRIVRLMHMFLTRIMAIFPPDTQHKHEDLDLLYTAVSKMIAENLTSY 2188

Query: 2233 TAPQTSGDDNSFGSISFVLLVIKTLANVHKNFVDSYVL--VRILQRLARDLGSAVGSHPR 2290
                     + FG+    L+++K     + +++D  ++  +R+L  L RD  + +G +  
Sbjct: 2189 EKSPQPNASSLFGT----LMILKACTTNNASYIDRILVQFIRVLNHLTRDHINTIGGNTV 2244

Query: 2291 QGQRTDSDSAVTSSRQTADVGAVICNIKSVLELIDETVMLIADCKRSVTQILNTLLSEKG 2350
              Q  DS++        +        IK+ +      VM +   K  +  IL +L+ EK 
Sbjct: 2245 ISQSPDSNALPLELLVLSLE-----LIKNRI-----FVMSVEIRKLFIGTILVSLI-EKS 2293

Query: 2351 TDASVLLCILDMIKRWVEDDFSKTGASGLSGSFLTQKDVLTFLNKLSYIDKQHFSSEALE 2410
            T+  ++ CI+ M+  W+     KT    +     + ++    L KL    ++ F+ E   
Sbjct: 2294 TEVKIIKCIIKMLDEWI-----KTKEPNVMTQVPSIREKSALLVKLMQNVEKKFTDEI-- 2346

Query: 2411 EWDQKYLQLLYGLCADSTKYPLGLRQ-EVSLKVERHFMLGLRASHPGMRRKFFLLYHESL 2469
            E + ++L+++  +  D       L+Q E++ K+E  F+ GLR  +P +R KFF +   S+
Sbjct: 2347 ELNIQFLEIINFIYRDEI-----LKQTELTNKLEGAFLNGLRFQNPNVRSKFFEILDSSM 2401

Query: 2470 GKTLFARLQYIIQIQDWEALSDVFWLKQGLDLLLAILVEDKPISLA--------PNSARV 2521
             + L  RL YII  Q W+ +   +W+KQ ++LL  IL  +  + +         P+   V
Sbjct: 2402 RRRLHDRLLYIICSQAWDTIGSHYWIKQCIELL--ILTANTMMQIQCSNEQFKIPSITSV 2459

Query: 2522 LPLLPSDNPG----------------IQ--------HQAPANLEGPEEVTSMFDS----- 2552
            +P+  S+                   IQ        +    N +  E+   +  +     
Sbjct: 2460 IPVNSSETQENSFVSFLSSHSESFDIIQTVDDKDDVYDIDLNADRKEDCQQILPNRRVTL 2519

Query: 2553 --IVMKHAQFLSATSKLQVADVVIPLRELAHTDANVAYHLWVLVFPIVWVTLLKEEQVAL 2610
              +V K A+FL A   ++   +++   +L H D  +A  +W+ +FP +W    ++++  +
Sbjct: 2520 VELVYKQAEFLEANRNIRTDQMLVATSQLCHIDTQLAQSVWLSMFPRIWSIFTEDQRCNI 2579

Query: 2611 AKPMISLLSKDYHKKQQGHRPNVVQALLEGLQLSHPQPRMPSELIKYIGKTYNAWHLALA 2670
             K +I  LS   +  Q+   P+ +   +E L    P   +P  L+ Y+GK++N WH A+ 
Sbjct: 2580 TKELIPFLSSGTNVNQKDCHPSTLNTFVESLTKCAPPIYIPPNLLAYLGKSHNLWHRAIL 2639

Query: 2671 LLESHVMLFMNDSK-------------------CAESLAELYRLLNEEDMRFGLWKKRSI 2711
            +LE   +     SK                     +SL+++Y  ++EED+  GLW K + 
Sbjct: 2640 VLEDMAVNQSMQSKDIDGGENQFSDLDVQQSNNIFDSLSKMYSSMHEEDLWAGLWLKFAH 2699

Query: 2712 TAETRAGLSLVQHGFWQRAQSLFYQAMVKATQGTYN---NTVPKAEMCLWEEQWLHCASQ 2768
              ET   +S  Q GF++ AQ  +  AM K  Q   N   NT   +E+ LWE  W+ CA +
Sbjct: 2700 YPETNIAVSYEQMGFFEEAQGAYDLAMTKFKQDLSNGVVNTYVNSELLLWENHWMRCAKE 2759

Query: 2769 LSQWDALVDFGKS--IENYEILLDSLWKLPDWAYLKDHVIPKAQVEETP------KLRLV 2820
            L+QWD L+D+ ++   +N  ++L+S W++PDW  +K   I  A+ E+        K+ L 
Sbjct: 2760 LNQWDILLDYAQTNKDKNMFLILESSWRVPDWNLMK---IALAKTEQCYLKHYGFKINLY 2816

Query: 2821 QSYFALHDRNSNGVGDAENTVGKGVDLALEQWWQLPEMSVHARVPXXXXXXXXXXXXXSA 2880
            + Y ++  +     G+ E  V     L + +W +LP +  H  +P             ++
Sbjct: 2817 KGYLSILHQEERQTGNIERYVEIASSLCIREWRRLPNIVSHIHLPYLQASQQIMELHEAS 2876

Query: 2881 RIHVDIANGNKVSGNTAVGGLGNRYADLKDILETWRLRTPNEWDNMTVWYDMLQWRNEMY 2940
            +IH  +A               N   D+K I++TWR R P   D+++ W D+  WR   Y
Sbjct: 2877 QIHQGLAQSR-----------NNSLHDMKAIVKTWRNRLPIISDDLSHWSDIFTWRQHHY 2925

Query: 2941 NVVIDAFKDFATSNSPLHHLGFRDKAWNVNKLARIARKQGLYDVCVQILEKMYGHSTMEV 3000
             ++    +  +   S +  LG    A  +    +IARK  L  VC + L ++Y   ++ +
Sbjct: 2926 QIITQHLEQQSDQGSTM--LGVHASAQAIISFGKIARKHNLTGVCQETLSRIYTIPSVPI 2983

Query: 3001 QEAFVKIREQAKAYLEM-----KGERASGLNLINSTNLEYFPDKIKAEIFRLKGDFHLKL 3055
             + F KIR+Q K YL+M     K E    L +I STNL+YF  ++ AE + LKG    ++
Sbjct: 2984 VDCFQKIRQQVKCYLQMPSTSGKNEINEALEVIESTNLKYFTGEMNAEFYALKGLLLAQI 3043

Query: 3056 NDTESANIAYSNAITLFKNLPKGWISWGSYCDMAYQETQEEIWLEYAVSCFLQGIRFGV- 3114
              +E A  ++S A  L   L K W  WG Y +  + + ++      A+ C+LQ  R  + 
Sbjct: 3044 GRSEEAGKSFSVAAQLHDGLTKAWAMWGDYMEQIFLKERKITLAVDALICYLQASRNQIE 3103

Query: 3115 SNSRSHIARVLYLLSFDTANEPVGRVFDKHLDQVPHWVWLSWIPQLLLSLQRTEAPHCKL 3174
            S +R +IA+VL+ LS+D   + +    +KH+  +P   WL WIPQLL  L++ E      
Sbjct: 3104 SKTRKYIAKVLWFLSYDNNTKILISTLEKHVAGIPPSYWLPWIPQLLCCLEQFEGDVILN 3163

Query: 3175 VLLKIAAVFPQALYYWLRT-YL---LERRDAVNKSELGRLVLAQRMQQNATGAGHGGS-- 3228
            +L +I  ++PQA+Y+ +RT YL   +E+R+    +E         +       G G S  
Sbjct: 3164 LLSQIGRLYPQAVYFPIRTLYLTLKIEQREKHKTAEQAVKSSCSNIDGTTLSFGRGASHG 3223

Query: 3229 NLPSENQIHQGAQTSGAGGTHDSGNPHGQESERSTTENNLHPGSDQPMHQSSSAINDN-- 3286
            N+PS N I              +  P  + S+    +  +HP     +  S   I D   
Sbjct: 3224 NIPSINPI-------------KATPPMWRCSKVMQLQREVHP----TILSSLEGIVDQMV 3266

Query: 3287 ------NENTVRRNGASLAISAAGAFDAAKDIMEALRGKHNNLASELEVLLTEIGSRFVT 3340
                   E  +R+    L    A AF+    +      +H+ +       + ++GS F  
Sbjct: 3267 WFRESWTEEVLRQLRQGLIKCYAIAFEKRDTV------QHSTITPHTLHFVKKLGSTFG- 3319

Query: 3341 LPEERLLAVVNALLHRCYKYPTATTAEVPQPLKKELSGVCRACFSADAVTKHVEFVKEYK 3400
                  + + N         P + T+ +      E S   RA      VT      ++ K
Sbjct: 3320 ------IGIENV--------PGSVTSSISNSAASE-SLARRA-----QVTFQDPVFQKMK 3359

Query: 3401 QDFERHLDPESTTTFPATLAELTARLKKWKNILQSNVEDRFPAVLRLEDESRVLRDFN-- 3458
            + F    D          L  L ++LK W  +L++ V+ + P    +ED+ R L +F+  
Sbjct: 3360 EQFTNDFDFSKPGAM--KLHNLISKLKTWIKVLETKVK-KLPTSFLIEDKCRFLSNFSQK 3416

Query: 3459 VVDVEIPGQYFADQEVAPDHTVKLDRVGADVPIVRRHGSSFRRLTLIGSDGS-QKHFIVQ 3517
              +VE+PG+      ++  + V++ R    V IV+++ ++ RRL + G++G    + +V 
Sbjct: 3417 TAEVELPGELLI--PLSSHYYVRIARFMPRVEIVQKNNTAARRLYIRGTNGKIYPYLVVL 3474

Query: 3518 TSLTPNARSDERILQLFRVMNQMFDKHKESRRRHIGIHTPIIIPVWSQVRMVEDDLMYNT 3577
             S   +AR +ER+LQL R++N   +K KE+ RR + I  P ++P+  Q+R+ ED+    +
Sbjct: 3475 DSGLGDARREERVLQLKRMLNYYLEKQKETSRRFLNITVPRVVPISPQMRLAEDNPNSIS 3534

Query: 3578 FLEVYENHCARNDREADLPITHFKEQLNQAISGQISAEAIGDLRLQAYIDITKTLVNDSI 3637
             L++++  C     + D+PI  + ++L++  +          L  + + +I  T+V  ++
Sbjct: 3535 LLKIFKKCCQSMQVDYDMPIVKYYDRLSEVQAR--GTPTTHTLLREIFSEIQWTMVPKTL 3592

Query: 3638 FSQYMYKTLMSGSHMWAFKKQFAVQLAVSSFMSFMLQIGGRSPNKVLFAKNTGKMFQTDF 3697
               +  KT ++ +  W F+K   +QLA++      L +   + + +   +++G M  + F
Sbjct: 3593 LKHWALKTFLAATDFWHFRKMLTLQLALAFLCEHALNLTRLNADMMYLHQDSGLMNISYF 3652

Query: 3698 HPAYDANG---MIEFNEPVPFRLTRNMQAFFSQFGVEGLLMSSMCSAAQAVISSKQNEHL 3754
               +D N     +  + PVPFRLT N+  F + FG+ G L +++ + A+  I  + N  L
Sbjct: 3653 --KFDVNDDKCQLNQHRPVPFRLTPNVGEFITHFGITGPLSAAIVATARCFI--QPNYKL 3708

Query: 3755 RYQLAMFFRDELLSWFXXXXXXXXXXXXXXXATLNPAELKHK---VNANVEDVIKRIRGI 3811
               L    RDE+++                    +   ++H    VN+ V+ ++ R   I
Sbjct: 3709 SSILQTILRDEIIALQKKGFRECKLIEGSEDRYSDGNCMEHSVNIVNSAVDIIMTRFNKI 3768

Query: 3812 APQYFSEEDENTVEPPQSVQRGVNELVEAALSPRNLCMMDPTWHPWF 3858
            +  YF     +++E      + ++ LV++A +  NLC MDP WHPW 
Sbjct: 3769 S--YF-----DSIE-----NKKISVLVQSATNIDNLCRMDPAWHPWL 3803



 Score =  261 bits (668), Expect = 5e-68,   Method: Compositional matrix adjust.
 Identities = 197/642 (30%), Positives = 320/642 (49%), Gaps = 36/642 (5%)

Query: 286  VNLLVTC-SDSASIRKELLVSLKHVLGTDFKRGLFPLIDTLLDERVLVGTGRACFESLRP 344
            +NL+  C  ++A +RKELL++ +H+  TD ++   P I+ L DE +L+G G    +S+RP
Sbjct: 370  LNLMKNCPKEAAHLRKELLIAARHIFATDLRQKFIPSIEQLFDEDLLIGKG-VTLDSIRP 428

Query: 345  LAYSLLAEIVHHVRGDLSLAQLSRIIYLFSRNMHDSTLSLSIHTTCARLMLNLVEPIFEK 404
            LAYS LA++ HHVR  L++  L + + LFS+N+HD +L++ I T   +L+LNLV+ +  +
Sbjct: 429  LAYSTLADLAHHVRQSLNIDVLIKAVNLFSKNVHDESLAVGIQTMSCKLLLNLVDCL--R 486

Query: 405  GVDQQSMDEARILLGRILDAFVGKFSTFKRT-IPQLLEEGE--------VGKDRVTLRSK 455
               +     ++ LL ++L  FV KF T  +  +P ++++ +        V        S 
Sbjct: 487  HHSETEPQRSKALLSKLLKVFVKKFETIAKIQLPLIIQKCKGHAFSGALVNSSGNASLSH 546

Query: 456  LELP--VQAVLNLQVPVE-----HSKEVNDCKNLIKTLVMGMKTIIWS-------ITHAH 501
            +  P     + N+QV        +S  V + ++L+KTLV G+KTI W        +T   
Sbjct: 547  INAPDLKDDISNIQVSASGSQWIYSVNVAEFRSLVKTLVGGVKTITWGFFNSKFQLTDTK 606

Query: 502  LPRPQGMNPQALVSQSSAPQGFKGMREDEVWKASGVLKSGVHCLALFKEKDEEKEMLNLF 561
            L   + +    +V  S     +  M   +++  + V  +      L     EEKE+L  F
Sbjct: 607  LANHEKIFGPEIVC-SYIDLVYYAMEALDIYTIN-VNPNQQRTSGLISRSKEEKEVLEHF 664

Query: 562  SQILAIMEPRDLMDMFSLCMPELFESMINNNQLVQIFAALLQAPKVYKPFADVLINLLVS 621
            S I  +M  ++  ++FS  +  L E +  N  L  I  + L  P     FA VL+  L++
Sbjct: 665  SGIFLMMHSQNFQEIFSTTINFLVERIYKNQSLQVIANSFLANPTTSPLFATVLVEYLLN 724

Query: 622  SKLDVLKNPDSAATKLVLHLFRCIFGAVTKTPSDFERILQHHVPVIMEVCMKNATEVEKP 681
               ++  N + +   L L LF+ +FG+V+  P + E++L+ H+  I+   M+ A   E+P
Sbjct: 725  KMEEMGSNLERS--NLYLRLFKLVFGSVSLFPVENEQMLRPHLHKIVNRSMELALISEEP 782

Query: 682  LGYMQLLRTVFRGLAGCKYEXXXXXXXXXXXXXXNILLTMLEGPAGEDMKDLLLELCLTX 741
              Y  LLR +FR + G  ++                L  +  G   + M+DL +ELCLT 
Sbjct: 783  YNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLEGLNRLQSGFHKQHMRDLFVELCLTV 842

Query: 742  XXXXXXXXXXXXXXMKPLVFCLRGSDELVSLGLRTLEFWVDSLNPDFLEPSMANVMSEVI 801
                          M PLV  L GS  L+S GLRTLE  VD+L PDFL   +  V + ++
Sbjct: 843  PVRLSSLLPYLPMLMDPLVSALNGSPTLISQGLRTLELCVDNLQPDFLYDHIQPVRAALM 902

Query: 802  LALWSHLRPVPYPWGKKALQILGKLGGRNRRFLKEPLTLECKDNPEHGLRLVLTF-EPST 860
             ALW  LR         A ++LGK GG NR+ + EP  L    N +  + +V  F E  T
Sbjct: 903  QALWKTLRNQDNA-ALVAFRVLGKFGGGNRKMMVEPQALSYIINDKPTISIVTYFQEYET 961

Query: 861  PFLVPLDKFINLAVAAVIQRNHGMDIYYRKQALKFLRVCLLS 902
            P   P+D+ I  A  A+   ++  D +YR+Q+ + +R C L+
Sbjct: 962  PIDFPVDEAIKSAFRAL--GSNSTDQFYRRQSWEVIR-CFLA 1000



 Score = 58.2 bits (139), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 24/56 (42%), Positives = 42/56 (75%)

Query: 80  EILNRLPHSEVLRPFVQDLLKVAMQVLTADNEENGLICIRIIFDLLRNFRPTLENE 135
           E+++RLP +E LR  V+ ++ + +++L  DNEEN L+C+RII +L ++FRP+  +E
Sbjct: 146 EMIHRLPITESLRQHVKTIITMMLKILKTDNEENVLVCLRIIIELHKHFRPSFNSE 201

 Score =  582 bits (1500), Expect = e-165,   Method: Compositional matrix adjust.
 Identities = 479/1849 (25%), Positives = 850/1849 (45%), Gaps = 230/1849 (12%)

Query: 2081 EMIINFLIRVALVIEPKDRETNTMYKQALDLLSQALEV--WPSANVKFNYLEKLLSSMPP 2138
            E I+ FLI+  L + P+  E N + K+ L L +       W    +  N+ EK+L  M  
Sbjct: 2008 EAILTFLIKF-LSLFPEPVEENPLSKKGLSLFNDLFSFPRWKDCQLNSNFFEKILVDMDF 2066

Query: 2139 SQSDPSTALAQGLDVMNKVLEKQPHLFIRNNINQISQILEPCFKHKMLDAGKSLCSLLKM 2198
            + ++  T +A  L V   +L+ +   +I+   + I  +++   +   L    SL  ++ +
Sbjct: 2067 NDNNYRT-VANTLFVFGVILKNRGMEYIQREYSHIIALIDKSLRCGKLPVTHSLEQIILL 2125

Query: 2199 VFTAFPLDA-----ANTPPDIKLLYQKVNELINKHVNTVTAPQTSGDDNSFGSISFVLLV 2253
            +  + P  A      N   D K L   V      H N   A           +I   +  
Sbjct: 2126 LLQSHPTQAEEEEDTNEADDFKQLLLSV-----IHDNLAAA----------TNIESAICY 2170

Query: 2254 IKTLANVHKNFVDSYVLV--RILQRLARDLGSAVGSHPRQGQRTDSDSAVTSSRQTADVG 2311
            ++ + + +   +D  +L   +  Q++ARD   A      Q         VT    +  V 
Sbjct: 2171 LQIVKSSNPEALDGLLLPLNKCFQKVARDHIVACMQSAIQAS-----GKVTLPSASDTVS 2225

Query: 2312 AVICNIKSVLELIDETVMLIADCKRSVTQILNTLLSEKGTDASVLLCILDMIKRWVEDDF 2371
             ++    S +E+I   +  + D +R    ++  LL EK +   +   IL++ K WV    
Sbjct: 2226 KLLI---SFIEIIRVRMASLGDQRRWFLSVVVQLL-EKSSSFELCEHILNVTKEWVIVK- 2280

Query: 2372 SKTGASGLSGSFLTQKDVLTFLNKLSYIDKQHFSSEALEEWDQKYLQLLYGLCADSTKYP 2431
                      SFLT K+    L K+   + +  +   +E  D     LL  +  D    P
Sbjct: 2281 --------RDSFLTVKEKTALLLKMRTFEGRFDNKLYIEACD-----LLSTIYRD----P 2323

Query: 2432 LGLRQEVSLKVERHFMLGLRASHPGMRRKFFLLYHESLGKTLFARLQYIIQIQDWEALSD 2491
            +    E++ ++++ F+L   +    +R  F  ++  S+ + +++RL +I+    W+ +  
Sbjct: 2324 IFAHTELTARLKQAFLLATASKDTKIRMDFMDIFDSSMSRNVYSRLTFILDATSWDTIPS 2383

Query: 2492 VFWLKQGLDLLLAILVEDKPISLAPNSARVLPLLPSDNPGI--------QHQAPANLEGP 2543
            ++W+KQ   +LL  +   +P+ L  NS R  P+ P   P +        +H   A    P
Sbjct: 2384 IYWIKQANYILLGAINAKQPVRLTDNSLRFAPV-PMTKPILSSLPEVFSKHNGSA---IP 2439

Query: 2544 EEVTSMFDSIVMKHAQFLSATSKLQVADVVIPL---RELAHTDANVAYHLWVLVFPIVWV 2600
                + F  + +    FL    +L V  ++ PL   + L+  DAN    LW  +FP+ W 
Sbjct: 2440 LGRFTFFKQLDL----FLKRNKELTVQKIIFPLAHIQMLSDADAN---KLWQYIFPLAWK 2492

Query: 2601 TLLKEEQVALAKPMISLLSKDYHKKQQGHRPNVVQALLEGLQLSHPQPRMPSELIKYIGK 2660
             L  + +  L+K +I LL++DYH KQ  +RPNV+  L+        +  +P  L+KY+GK
Sbjct: 2493 ILSSDNRSDLSKSLIYLLTRDYHIKQVNNRPNVISTLVSSFVKCAAKLELPPHLVKYLGK 2552

Query: 2661 TYNAWHLALALLESHVM----LFMN---DSKCAESLAELYRLLNEEDMRFGLWKKRSITA 2713
             Y  +H +++LLE  +     ++ N       A+++AELY  LNE+DM +G W++     
Sbjct: 2553 LYGVYHESVSLLEIQLSDKYDMYQNAKVQESRADAVAELYASLNEDDMFYGHWRRNCKYL 2612

Query: 2714 ETRAGLSLVQHGFWQRAQSLFYQAMVKATQGTYNNTVP--KAEMCLWEEQWLHCASQLSQ 2771
            +T+  LS  Q G W RAQ L+ QA  KA     +  +P  ++E  LWE+QW+ CA +L Q
Sbjct: 2613 QTQVALSYEQLGMWGRAQQLYEQAQTKAR----SEAIPFSESEYNLWEDQWVMCAQKLQQ 2668

Query: 2772 WDALVDFGKSIENYEILLDSLWKLPDWAYLKDHV---IPKAQVEETPKLRLVQSYFALHD 2828
            WD L +  K   + E+LL+  W++ DW+  ++ +   I       TP+    Q +  L  
Sbjct: 2669 WDVLTELAKHEGSSELLLECAWRISDWSNNRESLEVAIKSLSDVPTPRKLTFQCFMTLQK 2728

Query: 2829 RNSN--GVGDAENTVGKGVDLALEQWWQLPEMSVHARVPXXXXXXXXXXXXXSARI--HV 2884
              S    + + +  + + + LAL +W QLPE    +                +A I  H+
Sbjct: 2729 SVSQPLAIKEFQQVLSEAIQLALIKWHQLPEKVNQSHYSLLHLFQQFVELQEAATIYSHL 2788

Query: 2885 DIANGNKVSGNTAVGGLGNRYADLKDILETWRLRTPNEWDNMTVWYDMLQWRNEMYNVV- 2943
            +  N   +  N  +         +K  L+ W+ R PN WD++ +W D++ WR  +++++ 
Sbjct: 2789 NAINFQNLPTNVQL---------IKSALQVWQERLPNVWDDINLWRDLISWRQIVFSMIN 2839

Query: 2944 ---------IDAFKDFATSNSPLHHL---GFRDKAWNVNKLARIARKQGLYDVCVQILEK 2991
                     I A     +SN P       G+ + AW +N+ A +ARK  L  VC+  L K
Sbjct: 2840 RVYLPLVPTIQANSSADSSNPPNTSFLFRGYHETAWLINRFAHVARKHKLPSVCLNQLTK 2899

Query: 2992 MYGHSTMEVQEAFVKIREQAKAYLEMKGERASGLNLINSTNLEYFPDKIKAEIFRLKGDF 3051
            +Y    +E+QEAF K+REQ   YL+   +  +GL ++ +TNL YF  + K+E   LKG F
Sbjct: 2900 IYTLPNIEIQEAFYKLREQVLCYLQNPRDLKTGLEVVTNTNLMYFNSRQKSEFVTLKGKF 2959

Query: 3052 HLKLNDTESANIAYSNAITLFKNLPKGWISWGSYCDMAYQETQEEIWLEY-AVSCFLQGI 3110
              KLN  E AN  Y+ A+ +   LPK W  WG Y D+ + ++ + +     A+SC+LQ  
Sbjct: 2960 LEKLNRGEEANQMYAAAVQIDLGLPKAWAEWGRYNDLLFNKSPDNLSAACNAISCYLQAA 3019

Query: 3111 -RFGVSNSRSHIARVLYLLSFDTANEPVGRVFDKHLDQVPHWVWLSWIPQLLLSLQRTEA 3169
              +  S +R  +ARVL+LLS + +   + + F+ +   +P W WL++IPQLL SL + + 
Sbjct: 3020 GTYQSSKARKMLARVLWLLSLNDSAGTIVKAFESYKGDIPVWHWLTFIPQLLNSLSKGDT 3079

Query: 3170 PHCKLVLLKIAAVFPQALYYWLRTYLLERRDAVNKSELGRLVLAQRMQQNATGAGHGGSN 3229
                +VL KIA  +PQAL++ LRT    R D                             
Sbjct: 3080 KCAPVVLKKIAKSYPQALFFTLRT---ARED----------------------------- 3107

Query: 3230 LPSENQIHQGAQTSGAGGTHDSGNPHGQESERSTTENNLHPGSDQPMHQSSSAINDNNEN 3289
                  I Q  +T  A    ++ + + +  +  + ++N         +QS++A   N E+
Sbjct: 3108 ------IAQVKRTEMAAWKSNTTDENKRNEDILSIQSNF-----LSTNQSTNAPATNKED 3156

Query: 3290 TVRRNGASLAISAAGAFDAAKDIMEALRGKHNNLASELEVLLTEIGSRFVTLPEERLLAV 3349
             + +            ++   +IM  L+  +  LA  +E L+ +I ++F    +     +
Sbjct: 3157 GLSKK----------VWEYIDEIMSILKTAYPLLALTMETLVDQIQAKFKCKNDGDAFRL 3206

Query: 3350 VNALLHRCYKYPTATTAEVPQPLKKELSGVCRACFSADAVTKHVEFVKE-YKQDFERHLD 3408
            V ALL+   ++ +     V   +K   S        AD +    ++ K+ +K+DF  + +
Sbjct: 3207 VVALLNDAVQH-SIRLGIVTDEMKLPSSTESNLSLFADNILP--DYCKQLFKEDFIVNSN 3263

Query: 3409 PESTTTFPATLAELTARLKKWKNILQSNVEDRFPAVLRLEDESRVLRDFN---VVDVEIP 3465
               +  F         +L+KW++  +  +  + P    LE  S  L +F+     ++E+P
Sbjct: 3264 GLKSYIF---------KLRKWRSYFE-RLLSKVPKKQYLEQYSSFLCEFHHQKFDEIEVP 3313

Query: 3466 GQYFADQEVAPDHTVKLDRVGADVPIVRRHGSSFRRLTLIGSDGSQKHFIVQTSLTPNAR 3525
            GQY   ++     +  ++R   +V ++  HG  +RRL++  + G+   F++Q     N+R
Sbjct: 3314 GQYLLHKDNNNSFSC-IERFLPEVELIVGHGVCYRRLSIRSNGGTIHPFVIQYPSARNSR 3372

Query: 3526 SDERILQLFRVMNQMFDKHKESRRRHIGIHTPIIIPVWSQVRMVEDDLMYNTFLEVYENH 3585
             +ER +QL R +N     + E+RRR +  + P +IP+ S +R++ED     T  ++YE +
Sbjct: 3373 REERFMQLTRYLNDALALNCETRRRCLKFYIPAVIPLSSHIRLLEDQPSSITLQKIYEIY 3432

Query: 3586 CARNDREADLPITHFKEQLNQ---AISGQISAEA-----------IGDLRLQAYIDITKT 3631
              RN+   D P   F  +L++    ++ QIS E+           +   R+  + +I K 
Sbjct: 3433 SERNNFSRDDPKELFTNELSKHMMELNSQISQESTDAEKLANRKQLFSRRIGMFENIQKL 3492

Query: 3632 LVNDSIFSQYMYKTLMSGSHMWAFKKQFAVQLAVSSFMSFMLQIGGRSPNKVLFAKNTGK 3691
                +I   Y      + S +W F+K F+ Q A  SF++++L I  R P K++F++++G 
Sbjct: 3493 YSPSTILKDYFSSIFTNYSDLWLFRKNFSYQYACFSFITYILSINNRIPAKLVFSRDSGG 3552

Query: 3692 MFQTDFHPAYDANGMIEFN-EPVPFRLTRNMQAFFSQFGVEGLLMSSMCSAAQAVISSKQ 3750
            ++ T+  P+  ++  +  N E VPFR T N++ F  +   EGLL  S+ + A+A+  SK 
Sbjct: 3553 VWTTEALPSMVSSTPVYHNGEIVPFRFTPNIKEFIGKTCTEGLLGPSIMAIARAL--SKP 3610

Query: 3751 NEHLRYQLAMFFRDELLSWFXXXXXXXXXXXXXXXATLNPAELK--HKVNANVEDVIKRI 3808
            +  L   L +F RD+L  W                    PA+    +KVN+N + +++R+
Sbjct: 3611 DFDLDMYLGIFIRDDLFWWLAQQTKGV------------PADFSMLNKVNSNTDLIMRRV 3658

Query: 3809 RGIAPQYFSEEDENTVEPPQSVQRGVNELVEAALSPRNLCMMDPTWHPW 3857
              ++   +     N        Q  ++ L +A+ S + L  MD  W PW
Sbjct: 3659 ASLSQVAYGNLPVN--------QTAIDYLAQAS-SSKVLAQMDVLWAPW 3698



 Score =  267 bits (682), Expect = 1e-69,   Method: Compositional matrix adjust.
 Identities = 244/956 (25%), Positives = 435/956 (45%), Gaps = 85/956 (8%)

Query: 8   EQHSRRLVDLDLPIPTRLEMVVEVRDSLEIAHTAEYLNFLKCYFPAF--SVILLQITKPQ 65
           E    RL D+ L    +    +E+RD+L+     E  NF + + P    ++ LL+  +P 
Sbjct: 45  EHWHNRLCDVGLDSKQKANTAIEIRDALDDVLVTEKTNF-ETFIPLLEDTLSLLEKERPV 103

Query: 66  FID-NPEHKLRNIVVEILNRLPHSEVLRPFVQDLLKVAMQVLTADNEENGLICIRIIFDL 124
           F      H+LR  ++E+L +    +    FV     V ++++  DNEE  ++ ++++  L
Sbjct: 104 FSSLAATHRLRIALLELLKKSGSYKGFEAFVNRTFAVLLRIVVNDNEEMAVLALKLVVLL 163

Query: 125 LRNFRPTLENEVQPFLDFVCKIYSIFRFTVSHFFDNVKMEEVKPMEMPTS------SDQS 178
            ++     +  VQ FL  V + Y      VS        E   P   P +      S  S
Sbjct: 164 FKDHSSLAKGHVQEFLSIVVENYKSMTTVVS--------EAFPPRSAPNTPSSHPMSAAS 215

Query: 179 LTPTPPIGNVQLNP-----STRSFKIITESPLVVMFLFQLYSRLVQTNIPHLLPLMVAAI 233
                 IG     P     ++ SFK+  E P++V  LFQ Y  L+   +P L PL++  I
Sbjct: 216 SASPAEIGMEHAGPKMIPKASSSFKVTAEFPIIVFLLFQTYKDLIPKMLPLLAPLVLQFI 275

Query: 234 SV-PGPENVPSHL----KPQFI-------------ELKGAQVKTVSFLTYLLKSCAEYIR 275
           S+ P P+     L    K  FI             +L  AQ+K+ SFL YLL+S    ++
Sbjct: 276 SLRPPPQAEARRLAESQKEVFIGVVPSLRRNHLYNDLISAQIKSFSFLAYLLRSFGAALK 335

Query: 276 PHEESICKSIVNLLVTC-SDSASIRKELLVSLKHVLGTDFKRGLFPLIDTLLDERVLVGT 334
             E SI    + L + C S+    R+ELLV+ +HVL TD+ RG  P +D LLD ++LVG+
Sbjct: 336 QFESSIPICTLQLFMDCPSELYQTRRELLVATRHVLSTDYLRGFLPYVDQLLDTKILVGS 395

Query: 335 GRACFESLRPLAYSLLAEIVHHVRGDLSLAQLSRIIYLFSRNMHDSTLSLSIHTTCARLM 394
           G     SLRP+A+S+LA+++H+VR +LS  Q+ ++I L+   + D   + +I     +L+
Sbjct: 396 GITSQHSLRPMAFSMLADMLHYVRMELSPQQIYKVILLYFSILMDDFYTSAIQAMATKLI 455

Query: 395 LNLVEPIFEKGVDQQSMDEARILLGRILDAFVGKFST----FKRTIPQLLEEGEVGKDRV 450
           LNLVE I    V  +    +R LL  IL   + K ++    F +    L E  ++ + ++
Sbjct: 456 LNLVERI----VALEDFSTSRSLLFAILLCLLRKLTSLNFEFMKLRDSLQENADLKQIKI 511

Query: 451 TLRSKLELPVQAVLNLQVPVEHSKEVNDCKNLIKTLVMGMKTIIWSITHAHLPRPQG--- 507
              +K +LP+              ++ DC  L K  ++G+K +++ +   ++P   G   
Sbjct: 512 E-ENKHDLPMFENPTGAAQPSGLDKLKDCIFLFKNTLLGIKPVLFGLKQRNIPLANGSIF 570

Query: 508 ------------MNPQALVSQSSAPQGFKGMREDEVWKASGVLKSGVHCLALFKEKDEE- 554
                          + L+ +    +  KG    +  + +GV KS  + LA + + D   
Sbjct: 571 TAQEWSEKLHLSSTNEVLLFRRLLVESLKGFSYYQTDEKTGVFKSSKN-LA-YSQLDSSL 628

Query: 555 ----------KEMLNLFSQILAIMEPRDLMDMFSLCMPELFESMINNNQLVQIFAALLQA 604
                     KE+L + + +   ++P   +++     P +FE +++N  L+ IF   +  
Sbjct: 629 TTNPSKLLEEKELLEMLATLFLHLDPSVFVEILESEFPNIFECLVDNLALLHIFQFWMSN 688

Query: 605 PKVYKPFADVLINLLVSSKLDVLKNPDSAATKLVLHLFRCIFGAVTKTPSDFERILQHHV 664
                    ++++    + L  + +  S    ++L LF+  F  V   P     +L+ H+
Sbjct: 689 EVTSVNCTGIVLSFCCDN-LAKIGSGQSTRVSVLLRLFKLAFMTVNVFPEKNAEVLRPHI 747

Query: 665 PVIMEVCMKNATEVEKPLGYMQLLRTVFRGLAGCKYEXXXXXXXXXXXXXXNILLTMLEG 724
             I+   ++  T+  +PL Y+ L++ +FR ++G K++                   ++  
Sbjct: 748 SYIISTSLELTTDAVEPLNYVYLMKALFRNISGGKFDSLYKEILPLLQVMLECFNRLIFT 807

Query: 725 PAGEDMKDLLLELCLTXXXXXXXXXXXXXXXMKPLVFCLRGSDELVSLGLRTLEFWVDSL 784
                 K+L  ELCLT               MKPL+  L+G  E+ S GLR  E  +D+L
Sbjct: 808 VTSTSQKELYAELCLTLPIRLSVLLPHMNFLMKPLIVALKGPPEIASQGLRIFELCLDNL 867

Query: 785 NPDFLEPSMANVMSEVILALWSH--LRPVPYPWGKKALQILGKLGGRNRRFLKEPLTLEC 842
             +FL+P + ++M ++++ LW+H  L        + A++ILGK+GGRNR+        + 
Sbjct: 868 TQEFLDPLLDSIMPDLLICLWNHSRLNQSNNQLHQSAVRILGKMGGRNRQIYLGTFGFDF 927

Query: 843 KDNPEHGLRLVLTFEPSTP-FLVPLDKFINLAVAAVIQRNHGMDIYYRKQALKFLR 897
             +      +  +F+ S+  F +   KF  L  +  +  N   D+  +KQA + ++
Sbjct: 928 LQDENIFPSIQFSFQGSSQNFSLEHSKF--LMSSCAVLNNQNSDLEEKKQAFQMVK 981



 Score =  152 bits (384), Expect = 7e-35,   Method: Compositional matrix adjust.
 Identities = 121/420 (28%), Positives = 198/420 (47%), Gaps = 13/420 (3%)

Query: 1156 IVRGLVYVLKRLPV-YASKEQEETSQVLMQILRVVNNV-DEANSEARRKSFQDVVEYLAT 1213
            I++ L ++LK  P  Y   +  E    ++ I      + D    + R  +  +       
Sbjct: 1197 ILKALFFILKDTPTDYGVLKLTEVRSFIVDITTQFCILQDVLAPKERANNIINAFSPFFL 1256

Query: 1214 ELFNPNASIPVRKNVQNCLALLASRTGSEVTXXXXXXXXXXXXXXIMRPLRSKTVDQQVG 1273
            EL +PN    VR  VQ  +  +++ +   V                 +PLR+     Q+G
Sbjct: 1257 ELLHPNDH--VRNTVQQAIENISNNSKLSVVDLLLPIKDRLLSPIFGKPLRALPFTIQIG 1314

Query: 1274 TVAALNFCLALRPPLLKVTPELVNFLQEALQIAEADET--VWAVKLMNPKVLTSLNRLRT 1331
             + A+ +CL   P  L +T EL    +E + +A+A++   V  +K    K  +SL +LR 
Sbjct: 1315 HIDAITYCLHRSPSFLDLTDELYRLFRETIALADAEDEALVTMLKTSQSKDSSSLRKLRA 1374

Query: 1332 ACIELLCTTMAWTDFRTQTHNELRAKIISMFFKSLTCRAPEIVAVAKEGLRQVINQ-QRM 1390
             C+ LL  ++    F    H + R KII++FFK L     EI +VA + LR V++Q Q++
Sbjct: 1375 TCLHLLFASLVAHKFDQPQHAQTRTKIIAIFFKDLYSPHKEIYSVAIDALRHVLSQNQKL 1434

Query: 1391 PKELLQSSLRPILVNLAHTKNLSMPXXXXXXXXXXXXSNWFNVTLGGKLLEHLKKWLEPE 1450
            PKELLQS LRPIL+NL+    LS+             +N+F V +G KLL+HL    + +
Sbjct: 1435 PKELLQSGLRPILMNLSDHNKLSVNGLEGLSRLLRLLTNYFKVEIGRKLLQHLNVLSDSK 1494

Query: 1451 KL-AQSQKAWKAGEEPKIAAAIIELFHLLPHAASKFLDELVTLTIDLEAALPPGQVYSEI 1509
             L   S    K     +I  +++ +F  LP  +++FL +L++  +++EA L   + YS  
Sbjct: 1495 VLETASLSLLKTNPRIEIIVSLVNVFRDLPPLSAQFLGDLLSSVVNIEAVL---RKYS-- 1549

Query: 1510 NSPYRLPLTKFLNRYAALAVDYFLSRLSEPKYFRRFMYIIRSDAGQPLREELAKSPQKIL 1569
            NSP R PL  F++ +A     Y L+         RF+  +     + LRE       K+L
Sbjct: 1550 NSPLRKPLYSFMDLHANDTWMYILNNARNGDLITRFVGALNDPMSEKLRETAGNYWGKLL 1609



 Score =  111 bits (278), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 55/168 (32%), Positives = 98/168 (58%), Gaps = 2/168 (1%)

Query: 1829 HRKELIKFGWNHLKREDSASKQWAFVNVCHFLDAYQAPEKIILQVFVALLRTCQPENKML 1888
            +RK +I   WN++K ED   KQ A+  +  F+ AY  P KI+  V+V++L+T QPE +  
Sbjct: 1827 YRKSVIMSAWNYIKLEDPMVKQAAYATIACFISAYDTPAKIVTPVYVSILKTYQPEVRAF 1886

Query: 1889 VKQALDILMPALPKRLPL-GDSRMPIWIRYTKKILVEEGHSIPNLIHIFLLVVRHSDLFY 1947
            ++ +L  L+  L  RL    DS  P+W +  + ++ E+   I   + ++  + +  DLF+
Sbjct: 1887 IEFSLASLLSVLTARLSSPSDSTFPLWAKLPRLVISEDVQGISQPLTVYQFICKAPDLFF 1946

Query: 1948 SCRAQFVPQMVNSLSRLGLPYNTTAENRRLAIELAGLVVSWERQRQNE 1995
            SC + F+  MVN+L +L    + + E R+LA+++    ++W+R +QNE
Sbjct: 1947 SCCSHFIVPMVNALPKLVSFSSASTEPRKLALDIVQTFINWQR-KQNE 1993

 Score =  561 bits (1445), Expect = e-159,   Method: Compositional matrix adjust.
 Identities = 400/1404 (28%), Positives = 679/1404 (48%), Gaps = 153/1404 (10%)

Query: 1830 RKELIKFGWNHLKREDSASKQWAFVNVCHFLDAYQAPEKIILQVFVALLRTCQPENKMLV 1889
            +K++IKF WN +K ED+  KQ A++   +F+  +  P K++ QVFVALLR+   E + LV
Sbjct: 1883 KKDIIKFCWNFIKLEDTLIKQSAYLVTSYFISKFDFPIKVVTQVFVALLRSSHVEARYLV 1942

Query: 1890 KQALDILMPALPKRLPLGDSRMPIWIRYTKKILVEEGHSIPNLIHIFLLVVRHSDLFYSC 1949
            KQ+LD+L P L +R+    +    WI + K+++VE   S  N+++ FL  + H DLF++ 
Sbjct: 1943 KQSLDVLTPVLHERMNAAGTP-DTWINWVKRVMVENSSSQNNILYQFL--ISHPDLFFNS 1999

Query: 1950 RAQFVPQMVNSLSRLGLPYNTTAENRRLAIELAGLVVSWERQR---QNEMKMVTDTDGTS 2006
            R  F+  +++ ++++    N+ +++  LAI+LA L++ WE +     N     TD+DG  
Sbjct: 2000 RDLFISNIIHHMNKITFMSNSNSDSHTLAIDLASLILYWENKTLEITNVNNTKTDSDGDV 2059

Query: 2007 QITDEMHTSSGADPKRSTDGSATSEDPSKRVKIEPGLQSICVMSPGGASSIPNVETPGSA 2066
             ++D   + S  +P  + D +A   D +    I   L+  C                   
Sbjct: 2060 VMSD---SKSDINPVEA-DTTAIIVDANNNSPISLHLREACTA----------------- 2098

Query: 2067 TQPDEEFKPNAAMEEMIINFLIRVALVIEPKDRETNTMYKQALDLLSQAL--EVWPSANV 2124
                               FLIR       +  ET  +  +A+++LS+ +  + W + NV
Sbjct: 2099 -------------------FLIRYVCASNHRAIETE-LGLRAINILSELISDKHWTNVNV 2138

Query: 2125 KFNYLEKLLSSMPPSQSDPSTALAQGLDVMNKVLEKQPHLFIRNNINQISQILEPCFKHK 2184
            K  Y EK L        +        LDV+    + +   +I  N+  I  +LE C K  
Sbjct: 2139 KLVYFEKFLIFQDLDSENILYYCMNALDVLYVFFKNKTKEWIMENLPTIQNLLEKCIKSD 2198

Query: 2185 MLDAGKSLCSLLKMVFTAFPLDAANT-----PPDIKLLYQKVNELINKHVNTVTAPQTSG 2239
              D  ++L  +L+++  A      +       P  K   Q +  +I + +   T+  T+G
Sbjct: 2199 HHDVQEALQKVLQVIMKAIKAQGVSVIIEEESPG-KTFIQMLTSVITQDLQE-TSSVTAG 2256

Query: 2240 DDNSFGSISFVLLVIKTLANVHKNFVDSYVLVRILQRLARDLGSAVGSHPRQGQRTDSDS 2299
                  ++++VL +         NF D+  +V +L  L +        H    Q  D+  
Sbjct: 2257 -----VTLAWVLFM---------NFPDN--IVPLLTPLMKTFSKLCKDHLSISQPKDA-M 2299

Query: 2300 AVTSSRQTADVGAVICNIKSVLELIDETVMLIADCKRSVTQILNTLLSEKGTDASVLLCI 2359
            A+  +R T  +      ++ VL ++   V L+ D +R     +  LL +   D + L  I
Sbjct: 2300 ALEEARITTKL------LEKVLYILSLKVSLLGDSRRPFLSTV-ALLIDHSMDQNFLRKI 2352

Query: 2360 LDMIKRWVEDDFSKTGASGLSGSFLTQKDVLTFLNKLSYID-------KQHFSSEALEEW 2412
            ++M + W+ +          +  F T K+    L K+   +        + F    L+ +
Sbjct: 2353 VNMSRSWIFN----------TEIFPTVKEKAAILTKMLAFEIRGEPSLSKLFYEIVLKLF 2402

Query: 2413 DQKYLQLLYGLCADSTKYPLGLRQEVSLKVERHFMLGLRASHPGMRRKFFLLYHESLGKT 2472
            DQ++                    E+++++E+ F++G R    G+R++F  +   SL + 
Sbjct: 2403 DQEHFN----------------NTEITVRMEQPFLVGTRVEDIGIRKRFMTILDNSLERD 2446

Query: 2473 LFARLQYIIQIQDWEALSDVFWLKQGLDLLLAILVEDKPISLAPNSARVLPLLPSDNPGI 2532
            +  RL Y+I+ Q+WE ++D  WL Q L LL      +K +SL      +  L P   P I
Sbjct: 2447 IKERLYYVIRDQNWEFIADYPWLNQALQLLYGSFNREKELSLK----NIYCLSP---PSI 2499

Query: 2533 -QHQAPANLEGPEEVTSM-FDSIVMKHAQFLSATSKLQVADVVIPLRELAHTDANVAYHL 2590
             Q   P N E   EV  +   + V  H   +    ++  +D +  L E+ + D    +  
Sbjct: 2500 LQEYLPENAEMVTEVNDLELSNFVKGHIASMQGLCRIISSDFIDSLIEIFYQDPKAIHRA 2559

Query: 2591 WVLVFPIVWVTLLKEEQVALAKPMISLLSKDYHKKQQGHRPNVVQALLEGLQLSHPQPRM 2650
            WV +FP V+ ++ K E+    + +I+LLSK YH +Q   R NV+  LL+ +        +
Sbjct: 2560 WVTLFPQVYKSIPKNEKYGFVRSIITLLSKPYHTRQISSRTNVINMLLDSIS-KIESLEL 2618

Query: 2651 PSELIKYIGKTYNAWHLALALLES-HVMLFMNDSKCAES----LAELYRLLNEEDMRFGL 2705
            P  L+KY+  +YNAW+ ++ +LES      ++++K  E+    L ELY  L EEDM +GL
Sbjct: 2619 PPHLVKYLAISYNAWYQSINILESIQSNTSIDNTKIIEANEDALLELYVNLQEEDMFYGL 2678

Query: 2706 WKKRSITAETRAGLSLVQHGFWQRAQSLFYQAMVKATQGTYNNTVPKAEMCLWEEQWLHC 2765
            W++R+   ET  GLS  Q G W +AQ L+  A VKA  G       ++E  LWE+ W+ C
Sbjct: 2679 WRRRAKYTETNIGLSYEQIGLWDKAQQLYEVAQVKARSGAL--PYSQSEYALWEDNWIQC 2736

Query: 2766 ASQLSQWDALVDFGKSIENYEILLDSLWKLPDWAYLKDHV---IPKAQVEETPKLRLVQS 2822
            A +L  WD L +  K     ++LL+  W++ DW   +D +   +       TP+ ++ ++
Sbjct: 2737 AEKLQHWDVLTELAKHEGFTDLLLECGWRVADWNSDRDALEQSVKSVMDVPTPRRQMFKT 2796

Query: 2823 YFALHDRNSNGVGDAE--NTVGKGVDLALEQWWQLPEMSVHARVPXXXXXXXXXXXXXSA 2880
            + AL +   +  GD E      +G+ L+L +W  LP     A                + 
Sbjct: 2797 FLALQNFAESRKGDQEVRKLCDEGIQLSLIKWVSLPIRYTPAHKWLLHGFQQYMEFLEAT 2856

Query: 2881 RIHVDIANGNKVSGNTAVGGLGNRYADLKDILETWRLRTPNEWDNMTVWYDMLQWRNEMY 2940
            +I+ ++         T V  L ++  ++K IL+ WR R PN WD++ +W D++ WR   +
Sbjct: 2857 QIYANL-------HTTTVQNLDSKAQEIKRILQAWRDRLPNTWDDVNMWNDLVTWRQHAF 2909

Query: 2941 NVVIDAFKDF------ATSNSPLH---HLGFRDKAWNVNKLARIARKQGLYDVCVQILEK 2991
             V+ +A+         + SNS ++   + G+ + AW +N+ A +ARK  + DVC+  L +
Sbjct: 2910 QVINNAYLPLIPALQQSNSNSNINTHAYRGYHEIAWVINRFAHVARKHNMPDVCISQLAR 2969

Query: 2992 MYGHSTMEVQEAFVKIREQAKAYLEMKGERASGLNLINSTNLEYFPDKIKAEIFRLKGDF 3051
            +Y    +E+QEAF+K+REQAK + +   E  +GL++I++TNL YF    KAE F LKG F
Sbjct: 2970 IYTLPNIEIQEAFLKLREQAKCHYQNMNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMF 3029

Query: 3052 HLKLNDTESANIAYSNAITLFKNLPKGWISWGSYCDMAYQETQEEI-WLEYAVSCFLQGI 3110
              KL   E AN A++ A+ +  NL K W  WG + D    E    I +   A+SC+LQ  
Sbjct: 3030 LSKLRAYEEANQAFATAVQIDLNLAKAWAQWGFFNDRRLSEEPNNISFASNAISCYLQAA 3089

Query: 3111 R-FGVSNSRSHIARVLYLLSFDTANEPVGRVFDKHLDQVPHWVWLSWIPQLLLSLQRTEA 3169
              +  S  R  + R+L+L+S D A+  +   FD    ++P W W+++IPQLL SL   EA
Sbjct: 3090 GLYKNSKIRELLCRILWLISIDDASGMLTNAFDSFRGEIPVWYWITFIPQLLTSLSHKEA 3149

Query: 3170 PHCKLVLLKIAAVFPQALYYWLRT 3193
               + +L++IA  +PQAL++ LRT
Sbjct: 3150 NMVRHILIRIAKSYPQALHFQLRT 3173



 Score =  332 bits (851), Expect = 2e-89,   Method: Compositional matrix adjust.
 Identities = 293/1129 (25%), Positives = 515/1129 (45%), Gaps = 152/1129 (13%)

Query: 1    MSPIQNFEQHSRRLVDLDLPIPTRLEMVVEVRDSLEIAHTAE-YLNFLKCYFPAFSVILL 59
            MS  +  EQ + R  D D  + +R   + E+ D +E+ ++ E Y  FL+   P     L 
Sbjct: 1    MSLTEQIEQFASRFRDDDATLQSRYSTLSELYDIMELLNSPEDYHFFLQAVIPLLLNQLK 60

Query: 60   QITKPQFIDNPEHKLRNIVVEILNRLPHSEVLRPFVQDLLKVAMQVLTADNEENGLICIR 119
            ++       +PE KLRN +++I NR   ++  +P+  ++L+  + VL  +NEENG++C++
Sbjct: 61   EVPISYDAHSPEQKLRNSMLDIFNRCLMNQTFQPYAMEVLEFLLSVLPKENEENGILCMK 120

Query: 120  IIFDLLRNFRPTLENEVQPFLDFVCKIYSIFRFTVSHFFDNVKMEEVKPMEMPTS----- 174
            ++  L ++F+  L++++  F+  + +IY      ++  F      E   ++ P       
Sbjct: 121  VLTTLFKSFKSILQDKLDSFIRIIIQIYKNTPNLINQTFYEAGKAEQGDLDSPKEPQADE 180

Query: 175  ---------------SDQSLTPTPPIGNVQ----LNPSTRSFKIITESPLVVMFLFQLYS 215
                           S QS T  P   N      L  S  SFKI++E P+ ++ L+  Y 
Sbjct: 181  LLDEFSKNDEEKDFPSKQSST-EPRFENSTSSNGLRSSMFSFKILSECPITMVTLYSSYK 239

Query: 216  RLVQTNIPHLLPLMVAAISV---------PGPENVPSHL---------KPQFIELKGAQV 257
            +L  T++P   PL++  +++            E+   H          +P + +   AQ+
Sbjct: 240  QLTSTSLPEFTPLIMNLLNIQIKQQQEAREQAESRGEHFTSISTEIINRPAYCDFILAQI 299

Query: 258  KTVSFLTYLL--KSCAEYIRPHEESICKSIVNLLVTC-SDSASIRKELLVSLKHVLGTDF 314
            K  SFL Y+       E+++ +   +   I+ LL  C S+ +S RKELL + +H+L T++
Sbjct: 300  KATSFLAYVFIRGYAPEFLQDYVNFVPDLIIRLLQDCPSELSSARKELLHATRHILSTNY 359

Query: 315  KRGLFPLIDTLLDERVLVGTGRACFESLRPLAYSLLAEIVHHVRGDLSLAQLSRIIYLFS 374
            K+   P +D L DER+L+G G    E+LRPLAYS +A+ +H++R +L L+++ + I +++
Sbjct: 360  KKLFLPKLDYLFDERILIGNGFTMHETLRPLAYSTVADFIHNIRSELQLSEIEKTIKIYT 419

Query: 375  RNMHDSTLSLSIHTTCARLMLNLVEPIFEKGVDQ-QSMDEARILLGRILDAFVGKFSTFK 433
              + D +L+L++    A+L+LNLVE I + G +  Q    A+ LL  I+D+++ +F T  
Sbjct: 420  GYLLDESLALTVQIMSAKLLLNLVERILKLGKENPQEAPRAKKLLMIIIDSYMNRFKTLN 479

Query: 434  RTIPQLL-----------EEGEVGKDRVT---------LRSKLE---------LPVQAVL 464
            R    ++           E+ E  K+ +          +R  LE          P +  +
Sbjct: 480  RQYDTIMKYYGRYETHKKEKAEKLKNSIQDNDKESEEFMRKVLEPSDDDHLMPQPKKEDI 539

Query: 465  NLQVPVEHSK---------EVNDCKN--------------------LIKTLVMGMKTIIW 495
            N    VE ++         E+ D KN                    L +TL+  +KTII 
Sbjct: 540  NDSPDVEMTESDKVVKNDVEMFDIKNYAPILLLPTPTNDPIKDAFYLYRTLMSFLKTIIH 599

Query: 496  SITHAHLPRPQGM--NPQALVSQSSAPQGFKGMREDEVWKASGVLKSGVHCLALFKEKDE 553
             +   + P  +    NP+   S S      +    +EV     +    +  L  FK+ +E
Sbjct: 600  DLKVFNPPPNEYTVANPKLWASVS------RVFSYEEVIVFKDLFHECIIGLKFFKDHNE 653

Query: 554  E------KEMLNLFSQIL---AIMEPRDLMDMFSLC----------------MPELFESM 588
            +      K+  ++    L   A  + R+LMD  +                  +P ++E M
Sbjct: 654  KLSPETTKKHFDISMPSLPVSATKDARELMDYLAFMFMQMDNATFNEIIEQELPFVYERM 713

Query: 589  INNNQLVQIFAALLQAPKVYKPFADVLINLLVSSKLDVLKNPDSAATKLVLHLFRCIFGA 648
            + ++ L+ +  + L +      FA +L+  L   KL  L N D   + +++ LF+  F +
Sbjct: 714  LEDSGLLHVAQSFLTSEITSPNFAGILLRFL-KGKLKDLGNVDFNTSNVLIRLFKLSFMS 772

Query: 649  VTKTPSDFERILQHHVPVIMEVCMKNATEVEKPLGYMQLLRTVFRGLAGCKYEXXXXXXX 708
            V   P+  E +L  H+  ++   +K +T  E+PL Y  L+RT+FR + G ++E       
Sbjct: 773  VNLFPNINEVVLLPHLNDLILNSLKYSTTAEEPLVYFYLIRTLFRSIGGGRFENLYRSIK 832

Query: 709  XXXXXXXNILLTMLEGPAGEDMKDLLLELCLTXXXXXXXXXXXXXXXMKPLVFCLRGSDE 768
                     L  M+        ++L +ELC+T               MKPLVF L+   +
Sbjct: 833  PILQVLLQSLNQMILTARLPHERELYVELCITVPVRLSVLAPYLPFLMKPLVFALQQYPD 892

Query: 769  LVSLGLRTLEFWVDSLNPDFLEPSMANVMSEVILALWSHLRPVPY--PWGKKALQILGKL 826
            LVS GLRTLE  +D+L  ++ +P +  V+ +V  AL++ L+P P+        ++ILGKL
Sbjct: 893  LVSQGLRTLELCIDNLTAEYFDPIIEPVIDDVSKALFNLLQPQPFNHAISHNVVRILGKL 952

Query: 827  GGRNRRFLKEPLTLECKDNPEHGLRLVLTFE-PSTPFLVPLDKFINLAVAAVIQRNHGMD 885
            GGRNR+FLK P  L  K   E  +  +  F+    P  VPL     +  A  I +++  D
Sbjct: 953  GGRNRQFLKPPTDLTEK--TELDIDAIADFKINGMPEDVPLSVTPGIQSALNILQSYKSD 1010

Query: 886  IYYRKQALKFLRVCLLSQLNLPGCVTDVGQTPRQLSTLLRSSVDSSWHRSEAVEIKADLG 945
            I+YRK A K+L   LL             + P   + LL+++V+S       +E   DL 
Sbjct: 1011 IHYRKSAYKYLTCVLLL------MTKSSAEFPTNYTELLKTAVNSIKLERIGIEKNFDLE 1064

Query: 946  -VKTKTQLMAEKSIFKTLLITILAAXXXXXXXXXXXXFVENICRHFAII 993
                K     ++++F  LL ++  A             + N+  HF ++
Sbjct: 1065 PTVNKRDYSNQENLFLRLLESVFYATSIKELKDDAMDLLNNLLDHFCLL 1113



 Score =  206 bits (523), Expect = 4e-51,   Method: Compositional matrix adjust.
 Identities = 160/617 (25%), Positives = 279/617 (45%), Gaps = 87/617 (14%)

Query: 3276 MHQSSSAINDNNENTVRRNGASLAISAAGAFDAAKDIMEALRGKHNNLASELEVLLTEIG 3335
            + + + A+  +  +T  RNG          ++  +++   L+  +  LA  LE L+ +I 
Sbjct: 3181 IQRQTMAVMGDKPDTNDRNGRR------QPWEYLQELNNILKTAYPLLALSLESLVAQIN 3234

Query: 3336 SRFVTLPEERLLAVVNALL-------------HRCYKYPTATTAEVPQPLKKELSGVCRA 3382
             RF +  +E L  ++N LL              +  K P  T   + +     L+   R 
Sbjct: 3235 DRFKSTTDEDLFRLINVLLIDGTLNYNRLPFPRKNPKLPENTEKNLVKFSTTLLAPYIRP 3294

Query: 3383 CFSADAVTKHVEFVKEYKQDFERHLDPESTTTFPATLAELTARLKKWKNILQSNVEDRFP 3442
             F+AD +        + K D+E ++                 RL+ W+  L++ + DR  
Sbjct: 3295 KFNADFI--------DNKPDYETYI----------------KRLRYWRRRLENKL-DRAS 3329

Query: 3443 AVLRLEDESRVLRDFN---VVDVEIPGQYFADQEVAPDHTVKLDRVGADVPIVRRHGSSF 3499
                LE     L +F+     D+EIPGQY  +++    H +K+ R    V  VR   SS+
Sbjct: 3330 KKENLEVLCPHLSNFHHQKFEDIEIPGQYLLNKDNNV-HFIKIARFLPTVDFVRGTHSSY 3388

Query: 3500 RRLTLIGSDGSQKHFIVQTSLTPNARSDERILQLFRVMNQMFDKHKESRRRHIGIHTPII 3559
            RRL + G DGS   F VQ     ++R +ER+ QL+R+ N+   K+ E+RRR I  + PI 
Sbjct: 3389 RRLMIRGHDGSVHSFAVQYPAVRHSRREERMFQLYRLFNKSLSKNVETRRRSIQFNLPIA 3448

Query: 3560 IPVWSQVRMVEDDLMYNTFLEVYENHCARNDREADLPITHFKEQLNQAISGQISAEAIGD 3619
            IP+  QVR++ D + + T  E++   C +   + D       ++LN A    + A  +  
Sbjct: 3449 IPLSPQVRIMNDSVSFTTLHEIHNEFCKKKGFDPDDIQDFMADKLNAAHDDALPAPDMTI 3508

Query: 3620 LRLQAYIDITKTLVNDSIFSQYMYKTLMSGSHMWAFKKQFAVQLAVSSFMSFMLQIGGRS 3679
            L+++ +  I    V  ++   +           W F+KQFA Q +   FMS+M+ I  R+
Sbjct: 3509 LKVEIFNSIQTMFVPSNVLKDHFTSLFTQFEDFWLFRKQFASQYSSFVFMSYMMMINNRT 3568

Query: 3680 PNKVLFAKNTGKMFQTDFHPA---YDA---------------NGMIEFNEPVPFRLTRNM 3721
            P+K+   K +G +F  +  P+   Y+                + +   NEPVPFRLT N+
Sbjct: 3569 PHKIHVDKTSGNVFTLEMLPSRFPYERVKPLLKNHDLSLPPDSPIFHNNEPVPFRLTPNI 3628

Query: 3722 QAFFSQFGVEGLLMSSMCSAAQAVISSKQNEHLRYQLAMFFRDELLSWFXXXXXXXXXXX 3781
            Q+      +EG+   ++ + ++A+I  + +  L   LA+F RDE++SWF           
Sbjct: 3629 QSLIGDSALEGIFAVNLFTISRALI--EPDNELNTYLALFIRDEIISWFSNLHRPIIE-- 3684

Query: 3782 XXXXATLNPAELKHKVNANVEDVIKRIRGIAPQYFSEEDENTVEPPQSVQRGVNELVEAA 3841
                   NP +L+  V  NV+ +I+++  +          +    P    + + + + +A
Sbjct: 3685 -------NP-QLREMVQTNVDLIIRKVAQLG---------HLNSTPTVTTQFILDCIGSA 3727

Query: 3842 LSPRNLCMMDPTWHPWF 3858
            +SPRNL   D  + PWF
Sbjct: 3728 VSPRNLARTDVNFMPWF 3744



 Score =  172 bits (436), Expect = 5e-41,   Method: Compositional matrix adjust.
 Identities = 125/464 (26%), Positives = 219/464 (47%), Gaps = 18/464 (3%)

Query: 1113 QLLPRLLHGCYGSTWXXXXXXXXXXXXXXXKVNVET--LCYFQVKIVRGLVYVLKRLPVY 1170
            +L  + +H CY  T+                V   +  L  +Q  +  GL++VLK     
Sbjct: 1192 ELAKQFIHLCYDETYYNKRGGVLGIKVLIDNVKSSSVFLKKYQYNLANGLLFVLKDTQSE 1251

Query: 1171 ASKEQEETSQVLMQILRVVNNVDEANSEARRKSFQDVVEYLATELFNPNASIPVRKNVQN 1230
            A     ++++ L+  L  +   D    +   K  ++ +  +  EL N N    VR   Q 
Sbjct: 1252 APSAITDSAEKLLIDLLSITFADVKEEDLGNKVLENTLTDIVCELSNANPK--VRNACQK 1309

Query: 1231 CLALLASRTGSEVTXXXXXXXXXXXXXXIMRPLRSKTVDQQVGTVAALNFCLALRPPLLK 1290
             L  +++ TG  +                 +PLR+     Q+G V A+ FCL+L    L 
Sbjct: 1310 SLHTISNLTGIPIVKLMDHSKQFLLSPIFAKPLRALPFTMQIGNVDAITFCLSLPNTFLT 1369

Query: 1291 VTPELVNFLQEALQIAEADETVWAVKLMNPKVLTS---LNRLRTACIELLCTTMAWTDFR 1347
               EL   LQE++ +A+A++   +  +      ++   L +LR ACI+LL   +   +F 
Sbjct: 1370 FNEELFRLLQESIVLADAEDESLSTNIQKTTEYSTSEQLVQLRIACIKLLAIALKNEEFA 1429

Query: 1348 TQTHNELRAKIISMFFKSLTCRAPEIVAVAKEGLR-QVINQQRMPKELLQSSLRPILVNL 1406
            T     +R +I+++FFK++   +PEI+    E L+  +    ++PKELLQ+ L+P+L+NL
Sbjct: 1430 TAQQGNIRIRILAVFFKTMLKTSPEIINTTYEALKGSLAENSKLPKELLQNGLKPLLMNL 1489

Query: 1407 AHTKNLSMPXXXXXXXXXXXXSNWFNVTLGGKLLEHLKKWLEPEKLAQSQKAWKAGEEP- 1465
            +  + L++P              +F V +G KLL+HL  W   E L        A + P 
Sbjct: 1490 SDHQKLTVPGLDALSKLLELLIAYFKVEIGRKLLDHLTAWCRVEVLDTLFGQDLAEQMPT 1549

Query: 1466 KIAAAIIELFHLLPHAASKFLDELVTLTIDLEAALPPGQVYSEINSPYRLPLTKFLNRYA 1525
            KI  +II +FHLLP  A  FL++L+     L+  L   ++  +++SP+R PL ++LNR+ 
Sbjct: 1550 KIIVSIINIFHLLPPQADMFLNDLL-----LKVMLLERKLRLQLDSPFRTPLARYLNRFH 1604

Query: 1526 ALAVDYFLSRLSEPKYFRRFMYIIRSDAGQPLREELAKSPQKIL 1569
                +YF   ++     R+ +  + +   +P  +ELA+  +K L
Sbjct: 1605 NPVTEYFKKNMT----LRQLVLFMCNIVQRPEAKELAEDFEKEL 1644