Query: CNT0041823
Subject: sp|E7FAW3|NBEL2_DANRE Neurobeachin-like protein 2 OS=Danio rerioOS=Dictyostelium discoideum GN=lvsC PE=3 SV=2
Score = 464 bits (1195), Expect = e-130, Method: Compositional matrix adjust.
Identities = 261/684 (38%), Positives = 370/684 (54%), Gaps = 73/684 (10%)
Query: 2153 KDRSWPMSSLHQIXXXXXXXXXXALELFMVDRSNFFFDFGNTEGRRNAYRAIVQARPPHL 2212
K + WP + + A+E+FM D++N+ F+F E R Y I +
Sbjct: 1767 KIKRWPNEMIKDVHLRRYLLRGSAIEIFMRDKTNYLFNFKKNE-RNKVYNKINSVKREFS 1825
Query: 2213 NNIYLATQRPEQLLRRTQLMERWARWEISNFEYLMQLNTLAGRSYNDITQYPVFPWIIXX 2272
T P +L++ W ISNF+YLM LNT+AGR+YND+TQYPVFPW+I
Sbjct: 1826 KE---PTLSPSDMLKKA--TSEWQARRISNFDYLMTLNTIAGRTYNDLTQYPVFPWVIAD 1880
Query: 2273 XXXXXXXXXXXXTFRDLSKPIGALNPERLKKFQERYSSFEDPVIPKFHYGSHYSSAGAVL 2332
TFRDLSKPIGALN +RL+ F++RY SF+DPVIPKF+YGSHYSSAG VL
Sbjct: 1881 YTSPVLDLNKAETFRDLSKPIGALNEKRLEIFKDRYESFDDPVIPKFYYGSHYSSAGIVL 1940
Query: 2333 YYLARVEPFTTLSIQLQGGKFDHADRMFSDFPGTWNGVLEDMSDVKELVPELFYLPEVLT 2392
+YL R+EPFTT + LQGG+FDH DRMF W+ L +DVKEL+PE +Y+PE LT
Sbjct: 1941 FYLIRLEPFTTQFLNLQGGRFDHPDRMFDSIALAWDNSLTSSTDVKELIPEFYYMPEFLT 2000
Query: 2393 NENSIDFGTTQLGEKLDAVKLPPWAKNPVDFVHKQRRALESEHVSAHLHEWIDLIFGYKQ 2452
N N I+FG Q G ++ V LPPWA +P DF+ R ALES++VS+HLHEWIDLIFG KQ
Sbjct: 2001 NHNHINFGIKQNGIGIEDVLLPPWASSPSDFIRINREALESDYVSSHLHEWIDLIFGIKQ 2060
Query: 2453 RGKEAIMANNVFFYITYEGTVDIDKITDPVQQRATQDQIAYFGQTPSQLLTVP-HMKRMP 2511
RGK+A NVF+Y+TYEG+VDID I D +RAT+ QI FGQTP+QL + H++R P
Sbjct: 2061 RGKQAKEVFNVFYYLTYEGSVDIDSIEDETTRRATESQINNFGQTPTQLFSKKHHIQRDP 2120
Query: 2512 LKDVLHMQTIFRNPKEIKPYTVQTPERCNLPASAI--------QASSDSVVIVDMNVPAA 2563
L + H+ + P +++ Y ++ + + I +D V ++D +
Sbjct: 2121 LNES-HISILKTPPNQLQAYFLKITNKNPIVYVYIPEPNPIMSYLVADKVTVID---KSR 2176
Query: 2564 RVAQHKWQPNTPDGQGTPFLFHHGKATTTSTSGSLMRMFKGPASSGTGDWQFPQAQAFAS 2623
HKW P+TP+ + +PF F ++TT L FA+
Sbjct: 2177 TTTNHKWFPSTPNDKISPFTFELDPSSTTKRRIGL---------------------PFAN 2215
Query: 2624 SGIRSSSVIAITSDGE-IITGGHADNSIKLVSSDGAKTLETAFGHCAPVTCLALSPDNNF 2682
S + AITSDG +I+ H DNS KL D AK +++ H VTCL+L+ D
Sbjct: 2216 DVTISPNCFAITSDGRYVISCAHWDNSFKLSFVDSAKLIQSVVKHKDTVTCLSLASDGQT 2275
Query: 2683 LVTGSRDSTVLLWRIHKAFTSRTSVXXXXXXXXXXXXXXXXXXXXXXXXKGKKCRLEGPI 2742
L+TGS+D+TV++WRI A T+++ G + P
Sbjct: 2276 LITGSKDTTVMVWRI--ATTNKS---------------------------GAPKFNDVPD 2306
Query: 2743 QVLRGHRRELXXXXXXXXXXXXXXXXXXXXXLLHSIRKGRLIRRLVGVKADS---LCISS 2799
+L GH E+ ++H+++ G +R + + + IS+
Sbjct: 2307 HILYGHDDEITCVDVNVGLDISISGSKDGTCIIHNLKHGEYVRSIYLPRQSPISLIAISN 2366
Query: 2800 DGVIMAWSSSEGSISVFTINGVLI 2823
G I+ +S ++ I +++ING L+
Sbjct: 2367 QGYIVIYSQADLMIYLYSINGGLL 2390
Score = 124 bits (311), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 157/726 (21%), Positives = 277/726 (38%), Gaps = 129/726 (17%)
Query: 268 VILRSCTRNRAMCSTAGLLGVLLRSVEAIISKDVDMKWNAAAILLLCIQHLAGHSLSVDD 327
V++ CT N+++C L+ LL ++ +V K +L I+ L HS++V +
Sbjct: 141 VMVEKCTTNQSVCCNCHLIYNLLEAIYKGQPMEVTTK------ILKLIERLGIHSVTVRE 194
Query: 328 LHRWLQVIKAA---ITTAWSSPLMLALEKAMSGKESRGPACTFEFDXXXXXXXXXXXXRW 384
L + ++K+ +S L+ L+ +S + GP F+FD +W
Sbjct: 195 LKKLFGLLKSEQGDYLPPTTSALLTTLQN-ISNSRNPGPQVYFDFDGKDSCIILPTFDKW 253
Query: 385 PFTNGYAFATWIYIESFADTLNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXH 444
PF G++F TW+ IESF D +
Sbjct: 254 PFPKGFSFCTWVRIESFVDP----------------------------------TGTPEY 279
Query: 445 MPRLFSFLSADNQGIEAYFHAQFLVVESGSGKGRKSSLHFTHAFKPQCWYFIGLEHSCKQ 504
PRLFSFLS GIE F Q L V + + K+ F + WYF+ + +S
Sbjct: 280 KPRLFSFLSDSGCGIEVLFIYQQLQVLTVNNHQSKAVFQSPPTFVEREWYFVSVVYSI-- 337
Query: 505 GLLGKAESELRLYIDGSLYESRPFDFPRISKPLSFCCIGTNPPPTMAGLQRRRRQCPLFA 564
L+ + +E+R+YI+G + IG N M+G R+CPL+
Sbjct: 338 NLI--SSNEIRIYINGQQSAKSSIKLNISGTLWNHFKIGNNSKK-MSG----ERECPLYG 390
Query: 565 EMGPVYIFKEPIGPERMARLASRGGDVLPCFGNGAGLPWLATNDYVRNKAEESSILDADI 624
+MG IF E + P ++ + + G + F + G + + ++ +
Sbjct: 391 QMGAFNIFDESLSPSQIQAIYTLGPNFNTSFQDVEG------------STKSAHTFESSL 438
Query: 625 GGYTHLLYHPCLLSGRFCPDASLSGAAGTLRRPAEVLGQVHVATR-MKPVESFWALAYGG 683
+ L Y+ L G C D + G A ++ +R +K + GG
Sbjct: 439 TSHLFLNYNCRALDGDLCLDNT-PDIGGDKNYDATLVSINPCVSRDIKDI----IYCLGG 493
Query: 684 PMSLLPLTV---SSVHKDSLE------PCLGNLPLSLST-------------VTLAAPVF 721
L PL + + SLE N LSLS+ + L V
Sbjct: 494 IKVLFPLIQQINNPISPLSLELITNENNNNNNNNLSLSSQQQTLEQLQQSINIKLTNQVL 553
Query: 722 RIMSVAIQHP-GNNEELCRTQGPEILARILSYLLHSLASLDRKHDGVGEEELVAAIVSLC 780
+ ++ N EE+ R QG ++ YLL ++ ++ +G + +
Sbjct: 554 ALFKFMLKESEANQEEMLRCQG----FSVMGYLLQQISP---EYLTIGCTNIFIDM---- 602
Query: 781 QSQKINHVLKVQLFRTLLLDLKIWSLCNYGLQKKLLSSLQDMVFTEATAMRDAEAIQLLL 840
+Q + L +++ L+L+ IW Y LQ+ LL ++ +VF + + D +QL+L
Sbjct: 603 SNQISDPTLVEEVYSNLMLNFCIWIKTKYELQRNLLVIIKQIVFEKYDQVSDIITVQLIL 662
Query: 841 DGCRRCYWM------------ISEKDSETTFPLDGNTRQMGELNAXXXXXXXXXXXXMGA 888
D YW KD + P N R++ ++ +
Sbjct: 663 DIMNDFYWYDDSKNEAHRNHHFFNKDILSKRPSISNIRELRQI----------LFEVLRI 712
Query: 889 ASPSLAADDLRRLLGFIIDSPQPNQVARVLHLMYRLVVQPNAARAQMFAEVFITSGGIET 948
+ D++ ++ F+I Q+ ++ + L + N Q F + + GG +
Sbjct: 713 LLRHQKSTDIQAIIKFLIYCKDYQQLIEMMEFV--LGLNGNGHNCQQFFDEIMGLGGTDV 770
Query: 949 LLVLLQ 954
L LL+
Sbjct: 771 FLTLLK 776
Query: CNT0041823
Subject: sp|Q6ZS30|NBEL1_HUMAN Neurobeachin-like protein 1 OS=Homo sapiensGN=nbeal2 PE=1 SV=1
Score = 451 bits (1161), Expect = e-126, Method: Compositional matrix adjust.
Identities = 310/930 (33%), Positives = 446/930 (47%), Gaps = 159/930 (17%)
Query: 1934 RAWRKLIRYLAEMRCFFGPFGDGICSPERVFWKLDSMESFSRMRQSIRRNYSGTDHHGAA 1993
R WR L R L+ R G + + PE V WKL S E++S+MR + NYS H A+
Sbjct: 1878 RHWRSLRRLLSSDR---GAWPLRV-QPE-VKWKLSSAETYSKMRLKLVPNYSFDSHSDAS 1932
Query: 1994 ADYDDQTETKSDNGSKGSQSNPPVVAAEVILMEIAYEEDEHGEGDQLDVKGNAEEHKRDE 2053
A D+ +D+ ++ P VA E + ++ + D+L+ DE
Sbjct: 1933 ALRDNM---GADSPRSSTEPLPLAVAREAKVSDM--------DDDKLE----------DE 1971
Query: 2054 GRISGSHEHASRTSAGNSDPRTSNDLEMVRDSSVVAPGFVPSELDERILLELPTSMVRPL 2113
+ + + S D E++ ++VA
Sbjct: 1972 DIVFLEEAEEAEEESQKEKLVLSEDCELI---TIVA------------------------ 2004
Query: 2114 RVVKGTFQITTRRINFIVDNRESQNLADHSDESQSGDQEKDRSWPMSSLHQIXXXXXXXX 2173
VV G ++TT + F + E + ++E D ++ P+S L ++
Sbjct: 2005 -VVPGRLEVTTHHLYFYDGSSEKEE----TEEGIGFDFKR----PLSQLREVHLRRYNLR 2055
Query: 2174 XXALELFMVDRSNFFFDFGNTEGRRN-AYRAIVQARPPHLNNIYLATQRPEQLLRRTQLM 2232
ALELF +D+S++F +F +G RN Y I+ RPP+L Y ++ P++LL+ + L
Sbjct: 2056 RSALELFFIDQSHYFINF--RKGVRNKVYSRILGLRPPNL--FYFGSRSPQELLKASNLT 2111
Query: 2233 ERWARWEISNFEYLMQLNTLAGRSYNDITQYPVFPWIIXXXXXXXXXXXXXXTFRDLSKP 2292
RW EISNFEYLMQLNT+AGR+YND++QYPVFPW++ FRDLSKP
Sbjct: 2112 HRWVCREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSAELDLDDPAVFRDLSKP 2171
Query: 2293 IGALNPERLKKFQERYSSFEDPV--IPKFHYGSHYSSAGAVLYYLARVEPFTTLSIQLQG 2350
IG +NP + +E+Y SFEDP I KFHYG+HYS+A V++Y+ R EPFT+L IQLQ
Sbjct: 2172 IGVVNPRHAQNVREKYESFEDPTGTIDKFHYGTHYSNAAGVMHYMIRTEPFTSLHIQLQS 2231
Query: 2351 GKFDHADRMFSDFPGTWNGVLEDMSDVKELVPELFYLPEVLTNENSIDFGTTQLG-EKLD 2409
GKFD ADR F W +E +DVKEL+PE FY PE L N N D G Q+ EK++
Sbjct: 2232 GKFDCADRQFHSIAAAWQARMESPADVKELIPEFFYFPEFLENMNGFDLGCLQISQEKVN 2291
Query: 2410 AVKLPPWAKNPVDFVHKQRRALESEHVSAHLHEWIDLIFGYKQRGKEAIMANNVFFYITY 2469
V LPPWA + DF+ K R+ALESEHVSAHLHEWIDLIFGYKQRG EA+ A NVF+Y TY
Sbjct: 2292 NVLLPPWASSREDFIRKHRKALESEHVSAHLHEWIDLIFGYKQRGPEAVEALNVFYYCTY 2351
Query: 2470 EGTVDIDKITDPVQQRATQDQIAYFGQTPSQLLTVPHMKRMPLKDVLHMQ--------TI 2521
EG VD+D I + +++A + I+ FGQTP QLL PH RM ++ +
Sbjct: 2352 EGAVDLDAIANETERKALEGIISNFGQTPCQLLKEPHPPRMSAENAFRRAARLDILPPNL 2411
Query: 2522 FRNPKEIKPYT---------VQTPERCNLPASAIQASSDSVVIVDMNVPAARVAQHKWQP 2572
F +++ + VQ N S I SD +V V N + H W P
Sbjct: 2412 FDQLSKLRSFKEVVSDGLALVQAVVPRNQTRSFIIPGSDILVTVSAN---GMIGTHSWLP 2468
Query: 2573 NTPDGQGTPFLFHHGKATTTSTSGSLMRMFKGPASSGTGDWQFPQAQAFASSGIRSSSVI 2632
+ F F + + + R GP S G S V+
Sbjct: 2469 YDKNIANY-FTFTRDPSVSNPKT---QRFLSGPFSPGVE---------------MGSQVL 2509
Query: 2633 AITSDGEII-TGGHADNSIKLVSSDGAKTLETAFGHCAPVTCLALSPDNNFLVTGSRDST 2691
++SDG ++ +GGH D S+++ AK + H VTCLAL +L++GSRD+T
Sbjct: 2510 VVSSDGRLLFSGGHWDCSLRVTMLGKAKLVGRICRHIDVVTCLALDLCGIYLISGSRDTT 2569
Query: 2692 VLLWRI--HKAFTSRTSVXXXXXXXXXXXXXXXXXXXXXXXXKGKKCRLEGPIQVLRGHR 2749
++W++ F+S S PIQVL GH
Sbjct: 2570 CMVWQVLQQGGFSSGLS--------------------------------PRPIQVLCGHD 2597
Query: 2750 RELXXXXXXXXXXXXXXXXXXXXXLLHSIRKGRLIRRL-------VGVKADSLCISSDGV 2802
+E+ ++HS+R+G+ + L V L + +G
Sbjct: 2598 QEVTCVAISTELDMAISGSKDGTVIVHSVRRGQYLWTLRPPCENCVSAPVAQLEVGMEGH 2657
Query: 2803 IMAWSSSEG--------SISVFTINGVLIA 2824
I+ + EG ++ V+++NG L+A
Sbjct: 2658 IVMQTVLEGRSAGKERYALHVYSVNGTLLA 2687
Score = 53.1 bits (126), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 26/99 (26%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
Query: 447 RLFSFLSADNQGIEAYFHAQFLVVESGSGKGRKSSLHF-THAFKPQCWYFIGLEHSCKQG 505
+L+SF +A G EA+F + ++V + K ++ H F W+ + + H +
Sbjct: 660 QLYSFFTASGTGFEAFFTTEEVLVVAVCTKKEYMAVSLPEHPFNDCAWHSVAIVHVPGRR 719
Query: 506 LLGKAESELRLYIDGSLYESRPFDFPRISKPLSFCCIGT 544
G ++ + +Y+DG ++ P FP +++P + CCIG+
Sbjct: 720 PFG--QNVVTVYVDGVQCKTAPLRFPSLNEPFTSCCIGS 756
Query: CNT0041823
Subject: sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiensGN=NBEAL1 PE=2 SV=3
Score = 448 bits (1153), Expect = e-125, Method: Compositional matrix adjust.
Identities = 311/1021 (30%), Positives = 491/1021 (48%), Gaps = 173/1021 (16%)
Query: 1862 WNTSEAMGVAWMECLQPVDTKSVYGKDFNA--LSYKFIAVLVASF---ALARNMQRSEID 1916
++ E M + W +C + + +++ +D KF + V F A N++ + +
Sbjct: 1703 YDGHENMALYWKDCYEAL-MVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNML 1761
Query: 1917 RRMQDDIIAANRLCLGSRAWRKLIRYLAEMRCFFGPFGDGICSPERVFWKLDSMESFSRM 1976
+++ +A R W+ + YL C GP+ +P + WKL ++E++SRM
Sbjct: 1762 KQLSSQQLAT------LRRWKAIQLYLT---CERGPWAKRKQNP--IHWKLANVENYSRM 1810
Query: 1977 RQSIRRNYSGTDHHGAAADYDDQTETKSDNGSKGSQSNPPVVAAEVILMEIAYEEDEHGE 2036
R + NY+ H A+A D+ G Q + P +++ +L+E+
Sbjct: 1811 RLKLVPNYNFKTHEEASALRDNL----------GIQHSQP--SSDTLLLEVV-------- 1850
Query: 2037 GDQLDVKGNAEEHKRDEGRISGSHEHASRTSAGNSDPRTSNDLEMVRDSSVVAPGFVPSE 2096
Q+ V E+ ++ E T+ N D + D +
Sbjct: 1851 -KQVKVSDMVED------KLDLPEEDI--TARVNVDEKEEQDQK---------------- 1885
Query: 2097 LDERILLELPTSMVRPLRVVKGTFQITTRRINFIVDNRESQNLADHSDESQSGDQEKDRS 2156
E+++L ++ + V+ G +ITT+ I F D S E + G D
Sbjct: 1886 --EKLVLMEDCELITIIDVIPGRLEITTQHIYFY----------DGSIEKEDG-VGFDFK 1932
Query: 2157 WPMSSLHQIXXXXXXXXXXALELFMVDRSNFFFDFGNTEGRRNAYRAIVQARPPHLNNIY 2216
WP S + +I ALE+F VD+SN+F +F E R Y ++ P N Y
Sbjct: 1933 WPHSQIREIHLRRYNLRRSALEIFHVDQSNYFLNF-KKEVRNKIYSRLLSLHSP---NSY 1988
Query: 2217 LATQRPEQLLRRTQLMERWARWEISNFEYLMQLNTLAGRSYNDITQYPVFPWIIXXXXXX 2276
++ P++L + + L ++W EISNF+YL+Q+NT+AGR+YND+ QYPVFPWI+
Sbjct: 1989 YGSRSPQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSE 2048
Query: 2277 XXXXXXXXTFRDLSKPIGALNPERLKKFQERYSSFEDPV--IPKFHYGSHYSSAGAVLYY 2334
FRDLSKPIG +N + K +E+Y +FEDP+ I KFHYG+HYS++ V++Y
Sbjct: 2049 ELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHY 2108
Query: 2335 LARVEPFTTLSIQLQGGKFDHADRMFSDFPGTWNGVLEDMSDVKELVPELFYLPEVLTNE 2394
L RVEPFTTL IQLQ G+FD ADR F P TW ++++ DVKEL+PE FY PE L N+
Sbjct: 2109 LIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQ 2168
Query: 2395 NSIDFGTTQLGEKL-DAVKLPPWAKNPVDFVHKQRRALESEHVSAHLHEWIDLIFGYKQR 2453
N + G Q+ ++L + V LP WAK+ DF++K R+ALESE+VSAHLHEWIDLIFGYKQR
Sbjct: 2169 NQFNLGRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQR 2228
Query: 2454 GKEAIMANNVFFYITYEGTVDIDKITDPVQQRATQDQIAYFGQTPSQLLTVPHMKRMPLK 2513
G A+ A NVF+Y +YEG VD+D +TD +++A + I FGQTP QLL PH R+ +
Sbjct: 2229 GPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAE 2288
Query: 2514 DVLHMQT--------IFRNPKEIKPYTVQTPE------RCNLPASAI-----QASSDSVV 2554
+ + T +F++ E+K + ++ + +P + Q S + ++
Sbjct: 2289 EAVQKPTKIDTSTLNLFQHLPELKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLI 2348
Query: 2555 IVDMNVPAARVAQHKWQPNTPDGQGTPFLFHHGKATTTSTSGSLMRMFKGPASSGTGDWQ 2614
+ MN + H W P + F F + T T+ R G
Sbjct: 2349 TISMNYV---IGTHGWLPYDRNISNY-FTFIKDQ---TVTNPKTQRSING---------- 2391
Query: 2615 FPQAQAFASSGIRSSSVIAITSDGEII-TGGHADNSIKLVSSDGAKTLETAFGHCAPVTC 2673
+FA +S + ++ D +++ + G+ DNSI+++S K + H VTC
Sbjct: 2392 -----SFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTC 2446
Query: 2674 LALSPDNNFLVTGSRDSTVLLWRIHKAFTSRTSVXXXXXXXXXXXXXXXXXXXXXXXXKG 2733
LA L++GSRD+T ++W+I T + V
Sbjct: 2447 LATDYCGIHLISGSRDTTCMIWQI----TQQGGVPVGLASK------------------- 2483
Query: 2734 KKCRLEGPIQVLRGHRRELXXXXXXXXXXXXXXXXXXXXXLLHSIRKGRLIRRL------ 2787
P Q+L GH E+ ++H+I+KG+ +R L
Sbjct: 2484 -------PFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCES 2536
Query: 2788 -VGVKADSLCISSDGVIMAWSSSE--------GSISVFTINGVL----IAKAKFPLFCSV 2834
+ + +L IS +G I+ +SS+E ++ +F+ING I K + C +
Sbjct: 2537 SLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICII 2596
Query: 2835 G 2835
G
Sbjct: 2597 G 2597
Score = 69.3 bits (168), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 124/583 (21%), Positives = 210/583 (36%), Gaps = 132/583 (22%)
Query: 447 RLFSFLSADNQGIEAYF-HAQFLVVESGSGKGRKSSLHFTHAFKPQCWYFIGLEHSCKQG 505
+L+SF + G EA+ H+ LVV + + + + H+F W+ I + H +
Sbjct: 618 QLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITVVHMPGKR 677
Query: 506 LLGKAESELRLYIDGSLYESRPFDFPRISKPLSFCCIGTNPPPTM--------------- 550
G +S + +Y +G S P FP +++P + CCIG+ T
Sbjct: 678 PFG--QSFVYIYDNGQQKVSAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPFSSP 735
Query: 551 --------------------------------AGLQRRRRQCP--LFAEMGPVYIFKEPI 576
AG Q CP L ++G V IF EP+
Sbjct: 736 ITPHRTSFGGILSSASWGGTIEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEPL 795
Query: 577 GPERMARLASRGGDVLPCFGNGAGLPWLATNDYVRNKAEESSILDADIGGYTHLLYHPCL 636
P ++ L G + L PW K +ES + AD+ G L Y
Sbjct: 796 QPPQVKALYLAGPNCLS--------PW---------KCQESDM--ADLPGNILLYYTAKA 836
Query: 637 LSGRFCPDASLSGAAGTLRRPAEVLGQVHVATRMKPVESFWALAYGGPMSLLPLTVSSVH 696
C D S + G L G V +K + + GG L PL H
Sbjct: 837 CKNSICLDLSTNCLHGRLT------GNKVVNWDIKDIIN----CIGGLNVLFPLLEQISH 886
Query: 697 ---------------KDSLEPCLGNLPLSLSTV--------TLAAPVFRIMSVAIQ-HPG 732
+S+ P G+ + ST L A I+ IQ HP
Sbjct: 887 FSEGQIPEEKNESTVPESVTPVEGDWLVWTSTKASESRLERNLVATFILIVKHFIQRHPI 946
Query: 733 NNEELCRTQGPEILARILSYLLHSLASLDRKHDGVGEEELVAAIVSLCQSQKINHVLKVQ 792
N L + G L +L + +L ++ + +L+ VSL + N L Q
Sbjct: 947 NQGNLIHSHGVATLGALLQKVPSTLMDVNV----LMAVQLLIEQVSL----EKNMQLLQQ 998
Query: 793 LFRTLLLDLKIWSLCNYGLQKKLLSSLQDMVFTEATAMRDAEAIQLLLDGCRRCYWMISE 852
+++ LL D +IW+ ++ + + L ++ R +Q LLD R Y
Sbjct: 999 MYQYLLFDFRIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYY----- 1053
Query: 853 KDSETTFPLDGNTRQMGELNAXXXXXXXXXXXXMGA--ASPSLAADDLRRLLGFIIDSPQ 910
GN + EL+ + + ++++ ++G+I + +
Sbjct: 1054 ----------GNGCKYNELSLDDIRTIRTSLYGLIKYFLCKGGSHEEIQSIMGYIAATNE 1103
Query: 911 PNQVARVLHLMYRLVVQPNAARAQMFAEVFITSGGIETLLVLL 953
Q+ +L +++ L ++ + R Q+F +F G + L LL
Sbjct: 1104 EEQLFGILDVLFSL-LRTSPTRGQLFLLLF-EPGNADILYALL 1144
Query: CNT0041823
Subject: sp|Q6ZQA0|NBEL2_MOUSE Neurobeachin-like protein 2 OS=Mus musculusGN=NBEAL2 PE=1 SV=2
Score = 446 bits (1148), Expect = e-124, Method: Compositional matrix adjust.
Identities = 298/930 (32%), Positives = 442/930 (47%), Gaps = 174/930 (18%)
Query: 1965 WKLDSMESFSRMRQSIRRNYSGTDHHGAAADYDDQTETKSDNGSKGSQSNPPVVAAEVIL 2024
WKL S E++SRMR + N+ H A+A D+ E + S A+V
Sbjct: 1827 WKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEVPLTPTEEASLPLAVTKEAKVST 1886
Query: 2025 MEIAYEEDEHGEGDQLDVKGNAEEHKRDEGRISGSHEHASRTSAGNSDPRTSNDLEMVRD 2084
+ED+ GE + +++ E + DE R
Sbjct: 1887 PPELLQEDQLGEDELAELETPMEAAELDEQR----------------------------- 1917
Query: 2085 SSVVAPGFVPSELDERILLELPTSMVRPLRVVKGTFQITTRRINFIVDNRESQNLADHSD 2144
E+++L +V + VV G ++TT+ + F + E
Sbjct: 1918 --------------EKLVLSAECQLVTVVAVVPGLLEVTTQNVYFYDGSTERV------- 1956
Query: 2145 ESQSGDQEKDRSWPMSSLHQIXXXXXXXXXXALELFMVDRSNFFFDF------------- 2191
E++ G R P++ L ++ ALELF +D++N+F +F
Sbjct: 1957 ETEEGIGYDFRR-PLAQLREVHLRRFNLRRSALELFFIDQANYFLNFPCKVGTTPVSSPS 2015
Query: 2192 -----------GNTEGRRNAYRAIVQARPPHLNNIYLATQRPEQLLRRTQLMERWARWEI 2240
+T+ R Y +++ RPP + YL+++ P+++LR + L ++W + EI
Sbjct: 2016 QTPRPQPGPIPPHTQVRNQVYSWLLRLRPP--SQGYLSSRSPQEMLRASGLTQKWVQREI 2073
Query: 2241 SNFEYLMQLNTLAGRSYNDITQYPVFPWIIXXXXXXXXXXXXXXTFRDLSKPIGALNPER 2300
SNFEYLMQLNT+AGR+YND++QYPVFPW++ FRDLSKPIG +NP+
Sbjct: 2074 SNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSNPAVFRDLSKPIGVVNPKH 2133
Query: 2301 LKKFQERYSSFEDP--VIPKFHYGSHYSSAGAVLYYLARVEPFTTLSIQLQGGKFDHADR 2358
+ +E+Y SFEDP I KFHYG+HYS+A V++YL RVEPFT+L +QLQ G+FD +DR
Sbjct: 2134 AQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDR 2193
Query: 2359 MFSDFPGTWNGVLEDMSDVKELVPELFYLPEVLTNENSIDFGTTQL-GEKLDAVKLPPWA 2417
F W LE +DVKEL+PE FY P+ L N+N D G QL EK+ V LPPWA
Sbjct: 2194 QFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWA 2253
Query: 2418 KNPVDFVHKQRRALESEHVSAHLHEWIDLIFGYKQRGKEAIMANNVFFYITYEGTVDIDK 2477
+P DF+ + R+ALESE+VSAHLHEWIDLIFGYKQRG A A NVF+Y TYEG VD+D
Sbjct: 2254 SSPEDFIQQHRQALESEYVSAHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDH 2313
Query: 2478 ITDPVQQRATQDQIAYFGQTPSQLLTVPHMKRMPLKDVLHM--------QTIFRNPKEIK 2529
+TD +++A + I+ FGQTP QLL PH R+ ++ H +IF++ E+K
Sbjct: 2314 VTDERERKALEGIISNFGQTPCQLLKEPHPTRLSAEEAAHRLARLDTNSPSIFQHLDELK 2373
Query: 2530 PYTVQ------------TPERCNLPASAI-QASSDSVVIVDMNVPAARVAQHKWQPNTPD 2576
+ + P R P S I Q S D +V V + + H W P
Sbjct: 2374 AFFAEVVSDGVPLVLALVPHR--QPHSFITQGSPDLLVTVSAS---GLLGTHSWLPYD-- 2426
Query: 2577 GQGTPFLFHHGKATTTSTSGSLMRMFKGPASSGTGDWQFPQAQAFASSGIRSSSVIAITS 2636
+ F K T + + R+ GP G+G S +A+
Sbjct: 2427 -RNISNYFSFSKDPTMGSHKT-QRLLSGPWVPGSG---------------VSGQALAVAP 2469
Query: 2637 DGEII-TGGHADNSIKLVSSDGAKTLETAFGHCAPVTCLALSPDNNFLVTGSRDSTVLLW 2695
DG+++ +GGH D S+++ + K L H VTCLAL +L++GSRD+T ++W
Sbjct: 2470 DGKLLFSGGHWDGSLRVTALPRGKLLSQLSCHLDVVTCLALDTCGIYLISGSRDTTCMVW 2529
Query: 2696 R-IHKAFTSRTSVXXXXXXXXXXXXXXXXXXXXXXXXKGKKCRLEGPIQVLRGHRRELXX 2754
R +H+ S P+QVL GH +
Sbjct: 2530 RLLHQGGLSVGLAPK-------------------------------PVQVLYGHGAAVSC 2558
Query: 2755 XXXXXXXXXXXXXXXXXXXLLHSIRKGRLIRRLVGVKAD------SLCISSDGVIMAWSS 2808
++H++R+G+ + L + A L + S+G I+ SS
Sbjct: 2559 VAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLGATFPGPIFHLALGSEGQIVVQSS 2618
Query: 2809 S--------EGSISVFTINGVLIAKAKFPL 2830
+ S+ ++++NG L +A PL
Sbjct: 2619 AWERPGAQVTYSLHLYSVNGKL--RASLPL 2646
Query: CNT0041823
Subject: sp|Q9ESE1|LRBA_MOUSE Lipopolysaccharide-responsive and beige-likeGN=Nbeal2 PE=2 SV=2
Score = 436 bits (1120), Expect = e-121, Method: Compositional matrix adjust.
Identities = 293/931 (31%), Positives = 438/931 (47%), Gaps = 168/931 (18%)
Query: 1960 PERVFWKLDSMESFSRMRQSIRRNYSGTDHHGAAADYDDQTETKSDNGSKGSQSNPPVVA 2019
P WKL S E++SRMR + N+ H A+A D+ E P+
Sbjct: 1810 PPAPHWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEA-------------PMTP 1856
Query: 2020 AEVILMEIAYEEDEHGEGDQLDVKGNAEEHKRDEGRISGSHEHASRTSAGNSDPRTSNDL 2079
E + +A + E +IS E G D L
Sbjct: 1857 TEETSLPLAVTK---------------------EAKISAPPEELPEEQLGEED---LAAL 1892
Query: 2080 EMVRDSSVVAPGFVPSELDERILLELPTSMVRPLRVVKGTFQITTRRINFIVDNRESQNL 2139
E + +++ + E E+++L +V + VV G +ITT+ + F + E
Sbjct: 1893 ESLMEAAEL------DEKREKLVLSAECQLVTVVAVVPGLLEITTQHVYFYDGSTERV-- 1944
Query: 2140 ADHSDESQSGDQEKDRSWPMSSLHQIXXXXXXXXXXALELFMVDRSNFFFDF-------- 2191
E++ G R P++ L ++ ALELF +D+SN+F +F
Sbjct: 1945 -----ETEEGIGHDFRR-PLAQLREVHLRRFNLRRSALELFFIDQSNYFLNFPHKVAASS 1998
Query: 2192 ----------------GNTEGRRNAYRAIVQARPPHLNNIYLATQRPEQLLRRTQLMERW 2235
+T+ R Y +++ RPP YL+++ P ++LR + L ++W
Sbjct: 1999 ASSPCQAPRPQLYPIPSHTQLRNQVYSLLLRLRPP--TQGYLSSRSPLEMLRASGLTQKW 2056
Query: 2236 ARWEISNFEYLMQLNTLAGRSYNDITQYPVFPWIIXXXXXXXXXXXXXXTFRDLSKPIGA 2295
+ EISNFEYLMQLNT+AGR+YND++QYPVFPW++ FRDLSKPIG
Sbjct: 2057 VQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPVLDLSNPAVFRDLSKPIGV 2116
Query: 2296 LNPERLKKFQERYSSFEDP--VIPKFHYGSHYSSAGAVLYYLARVEPFTTLSIQLQGGKF 2353
+NP+ + +E+Y SFEDP I KFHYG+HYS+A V++YL RVEPFT+L +QLQ G+F
Sbjct: 2117 VNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRF 2176
Query: 2354 DHADRMFSDFPGTWNGVLEDMSDVKELVPELFYLPEVLTNENSIDFGTTQL-GEKLDAVK 2412
D +DR F W LE +DVKEL+PE FY P+ L N+N D G QL EK+ V
Sbjct: 2177 DCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVV 2236
Query: 2413 LPPWAKNPVDFVHKQRRALESEHVSAHLHEWIDLIFGYKQRGKEAIMANNVFFYITYEGT 2472
LPPWA +P DF+ K R+ALESE+VS HLHEWIDLIFGYKQRG A A NVF+Y TYEG
Sbjct: 2237 LPPWAGSPEDFIQKHRQALESEYVSTHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGA 2296
Query: 2473 VDIDKITDPVQQRATQDQIAYFGQTPSQLLTVPHMKRMPLKDV--------LHMQTIFRN 2524
VD+D + D +++A + I+ FGQTP QLL PH R+ ++ + +IF+N
Sbjct: 2297 VDLDHVADERERKALEGIISNFGQTPCQLLKEPHPPRLSAEEAANRLARLDTNSPSIFQN 2356
Query: 2525 PKEIKPYTVQ------------TPERCNLPASAIQASSDSVVIVDMNVPAARVAQHKWQP 2572
++K + + P R + + Q+SSD +V V + + H W P
Sbjct: 2357 LNQLKAFFAEVVSEAVPLVLALVPHRQSH-SFITQSSSDMLVTVSA---SGLLGTHTWLP 2412
Query: 2573 NTPDGQGTPFLFHHGKATTTSTSGSLMRMFKGPASSGTGDWQFPQAQAFASSGIRSSSVI 2632
+ F F T S + ++ GP S +G S+ +
Sbjct: 2413 YDRNINNY-FTF---SKDPTMGSPKVQKLLSGPWVSDSG---------------VSAQAL 2453
Query: 2633 AITSDGEII-TGGHADNSIKLVSSDGAKTLETAFGHCAPVTCLALSPDNNFLVTGSRDST 2691
A+ DG+++ +GGH D S+++ S + L H VTCLAL +L++GSRD+T
Sbjct: 2454 AVAPDGKLLFSGGHWDGSLRVTSLPRGRLLNQLSRHLDIVTCLALDTCGIYLISGSRDTT 2513
Query: 2692 VLLWRIHKAFTSRTSVXXXXXXXXXXXXXXXXXXXXXXXXKGKKCRLEGPIQVLRGHRRE 2751
++WR+ + + P+QVL GH
Sbjct: 2514 CMVWRLLQQSGLSAGLAPK------------------------------PVQVLYGHVAA 2543
Query: 2752 LXXXXXXXXXXXXXXXXXXXXXLLHSIRKGRLIRRLVGVKA------DSLCISSDGVIMA 2805
+ ++H++R+G+ + L A L + ++G I+
Sbjct: 2544 VSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPPGATLPGPISHLALGAEGQIVV 2603
Query: 2806 WSSS--------EGSISVFTINGVLIAKAKF 2828
SS+ S+ ++++NG L A
Sbjct: 2604 QSSACERPGAQVTYSLHLYSVNGRLRASVTL 2634
Score = 52.8 bits (125), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 53/99 (53%), Gaps = 3/99 (3%)
Query: 447 RLFSFLSADNQGIEAYFHAQFLVVESGSGKGRKSSLHFTH-AFKPQCWYFIGLEHSCKQG 505
+L+SF ++ G EA+F A +V + + +++ +F W+ + + H G
Sbjct: 629 QLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYVTVNLPEVSFADSAWHCVAIVHV--PG 686
Query: 506 LLGKAESELRLYIDGSLYESRPFDFPRISKPLSFCCIGT 544
+++ + ++ DG L ++ PF FP +S+P S CCIG+
Sbjct: 687 RRPFSQNLVNVFKDGHLVKTVPFRFPSLSEPFSSCCIGS 725