RetrogeneDB ID: | retro_cfam_2183 | ||
Retrocopy location | Organism: | Dog (Canis familiaris) | |
| Coordinates: | X:74413540..74414068(-) | ||
| Located in intron of: | None | ||
Retrocopy information | Ensembl ID: | None | |
| Aliases: | None | ||
| Status: | NOVEL | ||
Parental gene information | Parental gene summary: | ||
| Parental gene symbol: | AEN | ||
| Ensembl ID: | ENSCAFG00000011521 | ||
| Aliases: | AEN, ISG20L1 | ||
| Description: | apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:25722] |
Retrocopy-Parental alignment summary:
>retro_cfam_2183
CCAGAAGATGACAAGAAAGATGGTGGCAATTGTGAGATGGTGGGTACAGGACCCAAGGGGCATGTCAGTTTCTTGGCTGG
ATGTAGCACTGTCAACTACCACGGAGATGTACTTTATGATGAGTACATCCTTCCACCCTGCTACATAGTTGACTACTGGA
CCAGATGGAGTAGTATCTGGAAGCATCACATGTTGAATGCTACACCCTTCAAGATCGCTCAGAGCCAGATTTTGAAGATA
CAGGAAAGACAGAGGGGGCATGCCATCCACAACTTCAAAGCTCTTCAGTACTTTCACTCTAAGTCCCTCACTCACGACAC
CTCCCATACCCCTTTCTTCCCCAACCAGAAGTCCAACTGCCTGAAGAATGCCACCATGTCTCTGAAGTGTCTCAACAAGA
AGCTTCTGAACCAGGGCATCTAGATTGGGCAAAGTGGACATTCCTCTGTGGAACATGCTCAGGCCACTATGGAGCTGTAC
AAGTTGGTTGAAGTCGAGTGGGAACAGCACCTGGCCCACGATCCCCCA
ORF - retro_cfam_2183 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
| Percent Identity: | 51.4 % |
| Parental protein coverage: | 54.94 % |
| Number of stop codons detected: | 1 |
| Number of frameshifts detected: | 0 |
Retrocopy - Parental Gene Alignment:
| Parental | PRPSKCVAIDCEMVGTGPRGRVSELARCSVVSYHGDVLYDKYIRPEMPIVDYRTRWSGVTRQHMRKAIPF |
| P...K.....CEMVGTGP.G.VS.LA.CS.V.YHGDVLYD.YI.P...IVDY.TRWS.....HM..A.PF | |
| Retrocopy | PEDDKKDGGNCEMVGTGPKGHVSFLAGCSTVNYHGDVLYDEYILPPCYIVDYWTRWSSIWKHHMLNATPF |
| Parental | QVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNLLHQ-PGLHTRTRVSLKDLALQLLH |
| ..AQ..ILK........GHA.HN.F.AL.Y.H..S.T.DT...P....Q..........SLK.L...LL. | |
| Retrocopy | KIAQSQILKIQERQ--RGHAIHN-FKALQYFHSKSLTHDTSHTPFFPNQKSNCLKNATMSLKCLNKKLLN |
| Parental | KKIQAGQHGHSSVEDATTAMELYRLVEVQWEQQQASSLP |
| ..I..GQ.GHSSVE.A...MELY.LVEV.WEQ..A...P | |
| Retrocopy | QGI*IGQSGHSSVEHAQATMELYKLVEVEWEQHLAHDPP |
Legend:
| * | Stop codon |
| > | Forward frameshift by one nucleotide |
| < | Reverse frameshift by one nucleotide |
(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)
Expression validation based on RNA-Seq data:
| Library | Retrocopy expression | Parental gene expression |
|---|---|---|
| SRP012049_cerebellum | 0 .00 RPM | 11 .51 RPM |
| SRP017611_brain | 0 .00 RPM | 6 .43 RPM |
| SRP017611_kidney | 0 .00 RPM | 2 .25 RPM |
| SRP017611_liver | 0 .00 RPM | 4 .86 RPM |
Canis familiaris was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_cfam_2183 retrocopy.
Canis familiaris was not studied using FANTOM5 data.
retro_cfam_2183 was not experimentally validated.
Retrocopy orthology:
Retrocopy retro_cfam_2183 has 0 orthologous retrocopies within eutheria group .Parental genes homology:
Parental genes homology involve 4 parental genes, and 4 retrocopies.| Species | Parental gene accession | Retrocopies number | |
|---|---|---|---|
| Canis familiaris | ENSCAFG00000011521 | 1 retrocopy |
retro_cfam_2183 ,
|
| Erinaceus europaeus | ENSEEUG00000007015 | 1 retrocopy | |
| Microcebus murinus | ENSMICG00000015849 | 1 retrocopy | |
| Tursiops truncatus | ENSTTRG00000014668 | 1 retrocopy |