RetrogeneDB ID: retro_cjac_4188

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: X:69397316..69398573(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: KAT7
• Ensembl ID: ENSCJAG00000007037
• Aliases: None
• Description: K(lysine) acetyltransferase 7 [Source:HGNC Symbol;Acc:17016]

Sequence

>retro_cjac_4188
ACTCTAGTACACCTTACAGGAAAACATGAGAGACATTTCTCCATCTTATGATGCCCACTCTATGATAACCTCTCAGCTGA
GTAATGCAAGATGTGAGCACAGAGCCGGAATAAGCAGATAGAAGAAAGGATGCTGTCTCACAGGCAAGATGACAACAGGC
CTGCAACCAGGCACCAGGCATCAACGGAGAGGCAGCTTTGATATAAGGAAAAAGTGGCTGAACTCAGGAGGAAAAGAAAT
TCTGGAATGAGCAAAGAACAGAAAGACAAGCAGATGGAACACAGACAGACCTATGGGAACACACCAGAACCTCTCATAGA
AAACCTGACAAGCGAGTATCACTTGGATCTTTTCCAAAGAGCACAAGCCCGGGCTTCAGAGGATTTGGAGAAGTTAAGGC
TGCAAGGCCAAATCACAGAGGGAAGCAACATGACTAAAACAATTGCTTTTGGCCGCTATGAACTTGATACCTGGTACCAT
TCTCCATATCCTGAAGAATATGCATGGCTGGGACATCTCTCTATGTGTGAATTCTGTTTAAAATATATGAAAAGCCAAAT
GATACTCCACCAGCACATGGCCAAGTGTGTGTGGAAACACCCACCTGGTGATGAGATATATCGCAAAGGTTCAATCTCCA
TGTTTGAAGTGGATGGCAAGAAAAACAAGATCTACTGCCAAAACCCATGCCTGTTGGCCAAACTTTTTCTGGACCACAAG
ACATTATATTACGATGTGGAACCCTTCCTGTTCTATGTTATGACAGAGGCGGACAACACTGGCTGTCACCTGATTGGGTA
TTTTTCCAAGGAAAAGAATTCATTCCTCAACTACAACATATCCTGTATCCTTACCATGCCTCAGTACATGAGACAGGGCT
ATGGCAAGATGTTCATTGATTTCAGTTATTTGCTTTCCAACGTCTAAGAAAAAGTTGGCTCCCCAGAATGTCCACTCTCA
GATCTGGGGCTTACAAGCCATCACAGTTACTGGAAAGAAGTACTTCACCGCTATCTGCATAATTTCCAATGCAAAGAGAT
TTCTGTTGAAGAAATCAGTCAGGAGACGGCTGTGAATCCCATGGACATTGTCAGTACTCTGCAAGCCCTTCAGATGCTCA
AGTACTGGAAGGGAAAACACCTAGTTTTAAAGAGACAGGACCTGATTGATGAGTGGATAGCCAAAGAGGCCAAAAGGTCC
AACTCCAGTAAAACCATGGATCCCAGCTGCTTAAAATGGACCCGTCCCAAGGGCACT

Alignment

ORF - retro_cjac_4188 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.05 %
• Parental protein coverage: 69.19 %
• Number of stop codons detected: 5
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  SLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYK
          .L.HLTGKHERHFSI..CPLY.NLSA..CK..AQSR.KQIEERMLSHRQDDN.R.ATRHQA.TERQL.YK
Retrocopy TLVHLTGKHERHFSIL*CPLYDNLSAE*CKM*AQSRNKQIEERMLSHRQDDN-RPATRHQASTERQL*YK

Parental  EKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQIT
          EKVAELR.KRNSG.SKEQK.K.MEHRQTYGNT.EPL.ENLTSEY.LDLF.RAQARASEDLEKLRLQGQIT
Retrocopy EKVAELRRKRNSGMSKEQKDKQMEHRQTYGNTPEPLIENLTSEYHLDLFQRAQARASEDLEKLRLQGQIT

Parental  EGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRK
          EGSNM.KTIAFGRYELDTWYHSPYPEEYA.LG.L.MCEFCLKYMKSQ.IL..HMAKCVWKHPPGDEIYRK
Retrocopy EGSNMTKTIAFGRYELDTWYHSPYPEEYAWLGHLSMCEFCLKYMKSQMILHQHMAKCVWKHPPGDEIYRK

Parental  GSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYN
          GSIS.FEVDGKKNKIYCQN.CLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYN
Retrocopy GSISMFEVDGKKNKIYCQNPCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYN

Parental  VSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISI
          .SCILTMPQYMRQGYGKM.IDFSYLLS.V.EKVGSPE.PLSDLGL.S..SYWKEVL.RYLHNFQ.KEIS.
Retrocopy ISCILTMPQYMRQGYGKMFIDFSYLLSNV*EKVGSPECPLSDLGLTSHHSYWKEVLHRYLHNFQCKEISV

Parental  KEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
          .EISQETAVNP.DIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNS.KTMDPSCLKWT.PKGT
Retrocopy EEISQETAVNPMDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSSKTMDPSCLKWTRPKGT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.29 RPM	16.57 RPM
SRP051959_heart	0.39 RPM	27.70 RPM
SRP051959_kidney	0.16 RPM	25.18 RPM
SRP051959_liver	0.28 RPM	14.43 RPM
SRP051959_lung	0.76 RPM	27.26 RPM
SRP051959_lymph_node	1.67 RPM	28.40 RPM
SRP051959_skeletal_muscle	0.26 RPM	29.61 RPM
SRP051959_spleen	1.51 RPM	25.82 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_4188 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_4188 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_4188 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 9 parental genes, and 10 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000016955	1 retrocopy	retro_cfam_1246,
Callithrix jacchus	ENSCJAG00000007037	1 retrocopy	retro_cjac_4188 ,
Homo sapiens	ENSG00000136504	1 retrocopy	retro_hsap_4878,
Gorilla gorilla	ENSGGOG00000007469	1 retrocopy	retro_ggor_3048,
Nomascus leucogenys	ENSNLEG00000003201	1 retrocopy	retro_nleu_2557,
Oryctolagus cuniculus	ENSOCUG00000000668	1 retrocopy	retro_ocun_1427,
Pongo abelii	ENSPPYG00000008925	1 retrocopy	retro_pabe_3795,
Pan troglodytes	ENSPTRG00000009383	1 retrocopy	retro_ptro_3250,
Tursiops truncatus	ENSTTRG00000000472	2 retrocopies	retro_ttru_1724, retro_ttru_1928,