RetrogeneDB ID: retro_ggor_1770

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 2b:43537039..43537394(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HEBP2
• Ensembl ID: ENSGGOG00000001584
• Aliases: None
• Description: None

Sequence

>retro_ggor_1770
ACACTGGGCTGGAAGGCCCCAGAGGTTGGAAGCCCCCAGCTCTGAAGTCACAGGATCTGACAGTGTGGACAGTTAAGTGG
GTCAGCACTTCTGTTGAGTCTATGAACAGGGGTTCAGCCATCCAGACAGGCTTTACAAAATTGAACATCTACATTCAAGG
CAAAAGGAGAAAGAGATGAAAATAATGGTGACAGCTCCAGTCACAAGCTACACAGAGGTTGGTTCATGTCCTTTTAGTGA
GTCTACCAAGACCATTTCCCTGTATATCTCCTCTGAACAGCAATTCCATCTGCCCAGGCCTTCAGAGTCAGATGACTTTA
TTGAAGACACAGCCAATATGCTGTGTTTCATTCAG

Alignment

ORF - retro_ggor_1770 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 69.42 %
• Parental protein coverage: 58.05 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  TPGWKAPEDAGPQPGSYEIRHYGP-AKWVSTSVESMDWDSAIQTGFTKLNSYIQGKN-EKEMKIKMTAPV
          T.GWKAPE...PQ..S..I...G...KWVSTSVESM...SAIQTGFTKLN.YIQGK..EKEMKI..TAPV
Retrocopy TLGWKAPEVGSPQL*SHRI*QCGQ<VKWVSTSVESMNRGSAIQTGFTKLNIYIQGKR<EKEMKIMVTAPV

Parental  TSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVR
          TSY.E.GS.PFSEST.TISLYI.SEQQF..PRP.ESD.FIED.A.M..F..
Retrocopy TSYTEVGSCPFSESTKTISLYISSEQQFHLPRPSESDDFIEDTANMLCFIQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	5.47 RPM
SRP007412_cerebellum	0.00 RPM	8.63 RPM
SRP007412_heart	0.00 RPM	10.16 RPM
SRP007412_kidney	0.00 RPM	16.31 RPM
SRP007412_liver	0.00 RPM	38.83 RPM
SRP007412_testis	0.00 RPM	2.49 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1770 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1770 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2333
Callithrix jacchus	retro_cjac_2727

---

Parental genes homology:

Parental genes homology involve 7 parental genes, and 7 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000019060	1 retrocopy	retro_cjac_2727,
Dasypus novemcinctus	ENSDNOG00000008868	1 retrocopy	retro_dnov_1268,
Echinops telfairi	ENSETEG00000009265	1 retrocopy	retro_etel_973,
Homo sapiens	ENSG00000051620	1 retrocopy	retro_hsap_2333,
Gorilla gorilla	ENSGGOG00000001584	1 retrocopy	retro_ggor_1770 ,
Loxodonta africana	ENSLAFG00000013501	1 retrocopy	retro_lafr_752,
Otolemur garnettii	ENSOGAG00000005010	1 retrocopy	retro_ogar_2762,