RetrogeneDB ID: retro_ggor_644

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:44635971..44637070(+)
• Located in intron of: ENSGGOG00000001931

Retrocopy information

• Ensembl ID: ENSGGOG00000007196
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: SEC14L5
• Ensembl ID: ENSGGOG00000007151
• Aliases: None
• Description: None

Sequence

>retro_ggor_644
TATACCGTTCACCCTGAAAATGAAGATTGGATGTGTTTTGAACAGTCTGCAAGTTTAGATATTAAATCTTTCTTTGGTTT
TGAAAGTACCATGGAAAAAATTGCAATGAAACAATATACCAGCAATATTAAAAAAAGGAAAGAAAATCATTGAATACTAC
CTTCGCCATTTAGAAGAAGGCATAACCTTTGTGCCCCATTGGACTCTACCTTCCATCACGCCCTCTTCAGAGACATCTTC
GTCATCCTGCAAGAAACAAGCAGCGTCCATGGCTGTTGTCATCCCAGATGCTGTCCTCAAGGAGGGTCTGAGTGGCGATG
CCCTCAGCAGCCCCAGCGCACCTGAGCCCGTGGTGGGCACCCCTGATAACAAACTAGATGCTGACTACTTCAAGAGATAC
CTGGGCGATTTGACTCCGCTGCAGGAGAGCTGTCTCATTAGACTTTGCGGGTGGCTCCAGGAGACCCACAAGGGTGAAAT
TCCAAAAGATGAGCATATTCTTCAGTTCCTATGTGCATGGGATTTTAATATTGACAAAGCCAGAGAGATCATTTGTCAAT
CTTTGGCGTGGAGGAAGCAGCACCAGGTAGACTACATTCTTCCTACCTGGGCCGTTCCACAGGTCCTTCAGAATTACTAC
ACGGGAGGCTGGCATCATCACGACAAAGATGGGTGGCCCCTCTGTGTGCTCAGGCTAGGGCAGATGGACACCAACGGCTT
GGTGAGAGCACTCAGGGAGGAAGCCCTGCTGAGATACGTTCTCTCCATAAATGAAGAAGAGCTAAGGCGATGTGAAGAGA
ATACAAAAGTCTTTGTTTGGCCTATCAGCTCATGGACCTGCCTGGCGGACTTGGAAGGGGTGAACATGCGCCACTTATGG
AGACCTGATGTCAAAGTGCTGCGGTGGATCATCGAGGTGGTGAAGGCCAGTTACCCTAAGAGACTGGGCCGACTTCTCAT
CCTGCGGGCACCCAGGGTATTTCCTGTGCTCTGGACGCTGGTTAGTCCATTTATTGATGACAACACCAGAAGGAAATTCC
TCATTTATGCAGGAAATGACTACCAGGGTCCTGGAGGCCTGCTGGATTACATTGATAGA

Alignment

ORF - retro_ggor_644 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 59.62 %
• Parental protein coverage: 56.99 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  YTVHPENEDWTCFEQSASLDIRSFFGFENALEKIAMKQYTANVKRVRA-YVEYILSQFKENEIHSYNMYY
          YTVHPENEDW.CFEQSASLDI.SFFGFE...EKIAMKQYT.N.K.......EY.L....E..........
Retrocopy YTVHPENEDWMCFEQSASLDIKSFFGFESTMEKIAMKQYTSNIKKRKE>IIEYYLRHLEEGI--TFVPHW

Parental  SFLIVTPASQGCGESSVRPGSECKPILLRILRTSPEGGNYLQFPGSKLPLLLQGD-KLDADYIERCLGHL
          .....TP.S.....S......................G..L..P....P.....D.KLDADY..R.LG.L
Retrocopy TLPSITPSSETSSSSCKKQAASMAVVIPDAVLKEGLSGDALSSPSAPEPVVGTPDNKLDADYFKRYLGDL

Parental  TPMQESCLIQLRHWLQETHKGKIPKDEHILRFLRARDFHLDKAREMLRQSLSWRKQHQVDLLLQTWQPPA
          TP.QESCLI.L..WLQETHKG.IPKDEHIL.FL.A.DF..DKARE...QSL.WRKQHQVD..L.TW..P.
Retrocopy TPLQESCLIRLCGWLQETHKGEIPKDEHILQFLCAWDFNIDKAREIICQSLAWRKQHQVDYILPTWAVPQ

Parental  LLEEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGEEALLRHVLSVNEEGQKRCEGSTRQLGRPISS
          .L...Y.GGWH..D.DG.PL..LRLGQMDT.GL..A..EEALLR.VLS.NEE...RCE..T.....PISS
Retrocopy VLQNYYTGGWHHHDKDGWPLCVLRLGQMDTNGLVRALREEALLRYVLSINEEELRRCEENTKVFVWPISS

Parental  WTCLLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLISPFINENTRRKFL
          WTCL.DLEG.NMRHLWRP.VK.L...IEVV...YP..LGRLLI.RAPRVFPVLWTL.SPFI..NTRRKFL
Retrocopy WTCLADLEGVNMRHLWRPDVKVLRWIIEVVKASYPKRLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFL

Parental  IYSGSNYQGPGGLVDYLDR
          IY.G..YQGPGGL.DY.DR
Retrocopy IYAGNDYQGPGGLLDYIDR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	10.79 RPM	48.15 RPM
SRP007412_cerebellum	14.70 RPM	13.79 RPM
SRP007412_heart	4.50 RPM	4.25 RPM
SRP007412_kidney	8.26 RPM	1.59 RPM
SRP007412_liver	4.09 RPM	1.19 RPM
SRP007412_testis	19.17 RPM	0.41 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_644 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_644 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 1 parental gene, and 1 retrocopy.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000007151	1 retrocopy	retro_ggor_644 ,