RetrogeneDB ID: retro_ggor_867

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 12:42035120..42035474(-)
• Located in intron of: ENSGGOG00000028620

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: IQCF1
• Ensembl ID: ENSGGOG00000012462
• Aliases: None
• Description: None

Sequence

>retro_ggor_867
AAGAAGCAGCCTAAAAAAATGAATAAACCCACACACACAAAAGATGAGCCTCAGCAGAAGGACATGCTGGCCCATTTTTC
TTCGGGACCATTAACCTCAAAGTTGAAGGCAGAGGCCAAAACTCTGGCTCTAGTTAAGACACAAACAGTGGCTAATGCCA
ATGAGAAATTTGGAAAACCCCCAGAAAACCAAAAGAAGCTCTCTGACAAAGATATGGCAGTCATCAAGATCCAAGTCTGG
TGTTGGGGCACCCTGGTGCATCAGGCACTGTGGCACACAGCCCTCAGCACCAGGATCATTCAGTGCTGATGGTGGCTGAT
ACTGTCCAGGATTCTGGAGATGAGGCAGTGGGCA

Alignment

ORF - retro_ggor_867 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 60.17 %
• Parental protein coverage: 55.61 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  EKQPKKTKEPSK-EDETQQKEMPTHLSLG---AESKAEAKTPVLVETQTVDNANGKSEKPPENQKKLSDK
          .KQPKK...P....DE.QQK.M..H.S.G......KAEAKT..LV.TQTV.NAN.K..KPPENQKKLSDK
Retrocopy KKQPKKMNKPTHTKDEPQQKDMLAHFSSGPLTSKLKAEAKTLALVKTQTVANANEKFGKPPENQKKLSDK

Parental  DTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRRA
          D....KIQ.W..GTLV..AL.H.ALS..IIQC.W.LILS.IL..R..A
Retrocopy DMAVIKIQVWCWGTLVHQALWHTALSTRIIQC*WWLILSRILEMRQWA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.04 RPM	0.04 RPM
SRP007412_heart	0.00 RPM	0.06 RPM
SRP007412_kidney	0.08 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.10 RPM	35.95 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_867 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_867 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 4 parental genes, and 4 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000173389	1 retrocopy	retro_hsap_1109,
Gorilla gorilla	ENSGGOG00000012462	1 retrocopy	retro_ggor_867 ,
Macaca mulatta	ENSMMUG00000004352	1 retrocopy	retro_mmul_860,
Pan troglodytes	ENSPTRG00000014977	1 retrocopy	retro_ptro_689,