RetrogeneDB ID: retro_ggor_987

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 13:23048594..23048972(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RGS17
• Ensembl ID: ENSGGOG00000026033
• Aliases: None
• Description: None

Sequence

>retro_ggor_987
TTGGGTCTTGAAGTAGCTGAAATGTGAAAAAGGCAGCAGTCCCAAAATGAAGGAACACCTGCTGTGTCTCAAGCGCCGGG
AAACCAGAGGCCCAACAACATCTGTTGCTTTTGTTGGTGCTGTTGTTGCAGCTGCTCCTGCCTCACTGTTAGGAATGAAG
AAAGAGGGGAAAATGCAGGAAGAACCACACACACTACAAAAATGGAGGGTATCCAGGTCCTAGAGGAATGCCAAAACCCC
ACTGCAGAGGAAGTCTTGCCGTGGTCTCAAAATTTTGACAAGATGATGAAGGCCCCAGCAGGAAGAAACCTTTTCAGAGA
GTTCCTCTGAACAGAATACAACAAAGAGAACCTACTTTTCTGGCTTGCCTGTGAAGAC

Alignment

ORF - retro_ggor_987 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 92.86 %
• Parental protein coverage: 58.06 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  LGPEVAEMRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMES
          LG.EVAEM.KRQQSQNEGTPAVSQAPGNQRPNN.CCFCWCCCCSCSCLTVRNEERGENAGR.THTTKME.
Retrocopy LGLEVAEM*KRQQSQNEGTPAVSQAPGNQRPNNICCFCWCCCCSCSCLTVRNEERGENAGRTTHTTKMEG

Parental  IQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACED
          IQVLEECQNPTAEEVL.WSQNFDKMMKAPAGRNLFREFL.TEY..ENLLFWLACED
Retrocopy IQVLEECQNPTAEEVLPWSQNFDKMMKAPAGRNLFREFL*TEYNKENLLFWLACED

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	1.10 RPM
SRP007412_cerebellum	0.00 RPM	1.85 RPM
SRP007412_heart	0.06 RPM	0.03 RPM
SRP007412_kidney	0.12 RPM	0.00 RPM
SRP007412_liver	0.16 RPM	0.00 RPM
SRP007412_testis	0.21 RPM	0.73 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_987 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_987 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1254
Pan troglodytes	retro_ptro_3042
Macaca mulatta	retro_mmul_1309

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Parental genes homology:

Parental genes homology involve 6 parental genes, and 6 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000091844	1 retrocopy	retro_hsap_1254,
Gorilla gorilla	ENSGGOG00000026033	1 retrocopy	retro_ggor_987 ,
Macaca mulatta	ENSMMUG00000019078	1 retrocopy	retro_mmul_1309,
Nomascus leucogenys	ENSNLEG00000015461	1 retrocopy	retro_nleu_2092,
Oryctolagus cuniculus	ENSOCUG00000021054	1 retrocopy	retro_ocun_1922,
Pan troglodytes	ENSPTRG00000029367	1 retrocopy	retro_ptro_3042,