RetrogeneDB ID: | retro_mmul_65 | ||
Retrocopy location | Organism: | Rhesus macaque (Macaca mulatta) | |
| Coordinates: | 6:58519230..58521030(-) | ||
| Located in intron of: | None | ||
Retrocopy information | Ensembl ID: | ENSMMUG00000010445 | |
| Aliases: | None | ||
| Status: | KNOWN_PROTEIN_CODING | ||
Parental gene information | Parental gene summary: | ||
| Parental gene symbol: | DLAT | ||
| Ensembl ID: | ENSMMUG00000017568 | ||
| Aliases: | None | ||
| Description: | dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial [Source:RefSeq peptide;Acc:NP_001244504] |
Retrocopy-Parental alignment summary:
>retro_mmul_65
ACTACAGGATATGGCGGAGTCCGGGTACTGTGTGGCTGGACCCCCAGCTCTGGGGCCACACCACGGAACCGCTTACTGCT
GCAGCTTTTGGGGTCACCCGGCCGCCGCTGTTACAGTCTTCCCCCGCATCAGAAGGTTCCATTGCCTTCTCTTTCCCCCA
CAATGCAGTCAGGCACCATAGCCCATTGGGAAAAAAAAGAGGGGGGCAAAATCAACGAAGGTGACCTAATTGCAGAAGTT
GAAACTGATAAAGCCACTGTTGGATTTGAGAGCCTGGAGGAGTGTTATATGGCAAAGATACTTGTTGCTGAAGGTACCAG
GGATGTTCCCATTGGAGCGATCATCTGTATCACAGTTGGCAAGCCTGAGGATATTGAGGCTTTTAAAAATTATACATTGG
ATTCCTCAGCAGCACCTACCCCACAGGCGGCCCCAGCACCAACCCCTGCTGCCACTGCTTCACCACCTACACCTTCTGCT
CAGGCTCCTGGTAGCTCATATCCCCCTCACATGCAGGTACTTCTTCCTGCCCTCTCTCCCACCATGACCATGGGCACAGT
TCAGAGATGGGAAAAAAAAGTGGGTGAGAAGCTAAGTGAAGGAGACTTACTGGCAGAGATAGAGACTGACAAAGCCACTA
TAGGTTTTGAAGTACAGGAAGAAGGTTATCTGGCAAAAATCCTGGTCCCTGAAGGCACAAGAGATGTCCCTCTAGGAACC
CCACTCTGTATCATTGTAGAAAAAGAGGCAGATATATCAGCATTTGCTGACTATAGGCCAACTGAAGTAACAGATTTAAA
ACCACAAGCACCACCACCTACCCCACCCCCGGTGGCCACTGTTCCTCTAACTCCCCAGCCTTTAGCTCCTACACCTTCAG
CACCCTGCCCAGCTACTCCTGCTGGACCAAAGGGAAGGGTGTTTGTTAGCCCTCTTGCCAAGAAGTTGGCAGTAGAGAAA
GGGATTGATCTTACACAAGTAAAAGGTACAGGACCAGATGGTAGAGTCACCAAGAAGGATATTGACTCTTTTGTGCCTAG
TAAAGCTGCTCCTGCTCCAGCAGCTGTTGTGCCTCCCACAGGTCCTGGAATGGCACCAGTTCCTACAGATGTCTTCACAG
ATATCCCAATTAGCAACGTTCATCAGGTTATTGCACAACGATTAATGCAATCAAAGCAAACCATACCTCATTATTACCTT
TCTATAGATGTAAATATGGGAGAAGTTTTGTTGGTACAGAAAGAACTTAATAAGATTTTAGAAGGGAGAAGCAAAATTTC
TGTCAATGACTTCATCATAAAAGCTTCAGCTTTGGCATGTCTAAAAGTTCCCGAAGCAAATTCTTCTTGGATGGACACAG
TTATGAGACAAAATCACATTGTTGATATCAGTGTTGCAGTCAGTACTCCTATAGGACTCATCACACCTATTGTGTTTAAT
GCACATATAAAAGGGCTAGAAACCATTACTAATGATGTTGTTTCTTTAGCAACCAAAGCAAGAGAGGGTAAACTACAGCC
ACACGAATTCCAGGGTGGCACTTTTACGATCTCCAATTTAGGACTGTTTGGAATTAAGAATTTCTCTGCTATTATTAACC
TACTTCAAGCATGTATTTTGGCAATTGGTGCTTCAGAGGATAAACTGGTTCCCACAGATAATGAAAAAGGGTTTGATGTG
GCTAGCATGATGTCTGTTACACTCAGTTGTGATCACCAGGTGGTGGATGGAGCAGTTAGAGACCAGTGGCTTGCTGAGTT
TAGAAAGTACCTTGAAAAACCTATCACCATGTTGTTGTAA
ORF - retro_mmul_65 Open Reading Frame is conserved.
Retrocopy - Parental Gene Alignment summary:
| Percent Identity: | 95.49 % |
| Parental protein coverage: | 92.58 % |
| Number of stop codons detected: | 0 |
| Number of frameshifts detected: | 0 |
Retrocopy - Parental Gene Alignment:
| Parental | TTGYGGVRALCGWTPSSGATPRNRLLLQLLGSPGRRCYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDK |
| TTGYGGVR.LCGWTPSSGATPRNRLLLQLLGSPGRRCYSLPPHQKVPLPSLSPTMQ.GTIA.WEKKEG.K | |
| Retrocopy | TTGYGGVRVLCGWTPSSGATPRNRLLLQLLGSPGRRCYSLPPHQKVPLPSLSPTMQSGTIAHWEKKEGGK |
| Parental | INEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYTLDSSPAPT |
| INEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYTLDSS.APT | |
| Retrocopy | INEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYTLDSSAAPT |
| Parental | PQAAPAPTPAATASPPIPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETD |
| PQAAPAPTPAATASPP.PSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETD | |
| Retrocopy | PQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETD |
| Parental | KATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQAPPPTPPPVAT |
| KATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQAPPPTPPPVAT | |
| Retrocopy | KATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQAPPPTPPPVAT |
| Parental | VPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKAA |
| VP.TPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGR.TKKDIDSFVPSKAA | |
| Retrocopy | VPLTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRVTKKDIDSFVPSKAA |
| Parental | PAPAAVVPPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKIL |
| PAPAAVVPPTGPGMAPVPT.VFTDIPISN...VIAQRLMQSKQTIPHYYLSIDVNMGEVLLV.KELNKIL | |
| Retrocopy | PAPAAVVPPTGPGMAPVPTDVFTDIPISNVHQVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVQKELNKIL |
| Parental | EGRSKISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIA |
| EGRSKISVNDFIIKASALACLKVPEANSSWMDTV.RQNH.VD.SVAVSTP.GLITPIVFNAHIKGLETI. | |
| Retrocopy | EGRSKISVNDFIIKASALACLKVPEANSSWMDTVMRQNHIVDISVAVSTPIGLITPIVFNAHIKGLETIT |
| Parental | NDVVSLAAKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADNEKGFDV |
| NDVVSLA.KAREGKLQPHEFQGGTFTISNLG.FGIKNFSAIIN..QACILAIGASEDKLVP.DNEKGFDV | |
| Retrocopy | NDVVSLATKAREGKLQPHEFQGGTFTISNLGLFGIKNFSAIINLLQACILAIGASEDKLVPTDNEKGFDV |
| Parental | ASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPVTMLL |
| ASMMSVTLSCDH.VVDGAV..QWLAEFRKYLEKP.TMLL | |
| Retrocopy | ASMMSVTLSCDHQVVDGAVRDQWLAEFRKYLEKPITMLL |
Legend:
| * | Stop codon |
| > | Forward frameshift by one nucleotide |
| < | Reverse frameshift by one nucleotide |
(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)
Expression validation based on RNA-Seq data:
| Library | Retrocopy expression | Parental gene expression |
|---|---|---|
| SRP007412_brain | 0 .11 RPM | 37 .31 RPM |
| SRP007412_brain_prefrontal_cortex | 0 .16 RPM | 36 .73 RPM |
| SRP007412_cerebellum | 0 .32 RPM | 33 .77 RPM |
| SRP007412_heart | 0 .35 RPM | 69 .07 RPM |
| SRP007412_kidney | 0 .00 RPM | 47 .18 RPM |
| SRP007412_liver | 0 .04 RPM | 8 .99 RPM |
| SRP007412_testis | 0 .08 RPM | 32 .57 RPM |
Macaca mulatta was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_mmul_65 retrocopy.
Macaca mulatta was not studied using FANTOM5 data.
retro_mmul_65 was not experimentally validated.
Retrocopy orthology:
Retrocopy retro_mmul_65 has 0 orthologous retrocopies within eutheria group .Parental genes homology:
Parental genes homology involve 2 parental genes, and 2 retrocopies.| Species | Parental gene accession | Retrocopies number | |
|---|---|---|---|
| Macaca mulatta | ENSMMUG00000017568 | 1 retrocopy |
retro_mmul_65 ,
|
| Otolemur garnettii | ENSOGAG00000008559 | 1 retrocopy |