RetrogeneDB ID: retro_ogar_2494

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873629.1:764263..764988(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSOGAG00000024301
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: MCL1
• Ensembl ID: ENSOGAG00000016421
• Aliases: None
• Description: myeloid cell leukemia sequence 1 (BCL2-related) [Source:HGNC Symbol;Acc:6943]

Sequence

>retro_ogar_2494
GACGAGATGGAAGCCCATGCTGCCAATGCCATCAAGTCCCCCGAAGGTAAGCTGGCCACATACAAGCCGGAGTCTCTCAG
GAAGCAACCAGAGGTCCTGCATTTGCTGGAGTTTGTCAGCGAGGCAGGTAACCGCCTAAGCATTGACGGGTCACTTCCTT
CAACATCAGCCCCAGCAGAGGAGGAGGATGAGTTATACTGGCAGTCGCTAGAGATCATCTCTCGGTACCTTTGGGAGCAG
GTGACCGGCACCAAGGATGCGAAGCCAATGGGCAGGGCAGGAGGCACCAGCAGGAAGGTGCTGGAGACCTTGCGCCACGT
CGGCGATGAGGTGCAGTGCAACCACAAGATGGCCTTCCGAGGCATGTTTTGCAAACTGGACATCAAAACCGGAGATGATG
TTAGATCTTTGTCTCGAGTGAGGGTCCATGTTTTCGGTTATGGCGTAACAAATTGGGACAGTGTTGTGACCCTAATTTCT
TTTGGTGGCTTTGTGGCCAAACACTTGAAGACCATAAACCAAGAAAGCTGCATCGAACCATTAGCAGAAAATATCTCAGG
TGTCCTTGTAAGGACAAAACAGGGACTGGCTAGTCAAACAACAAGGCTGGGATGGCTTTGTGGAGTTCTTCCACCTGGAA
GACCTACAAAGCAGCATCAGAAACGTGCTGCTGGCTTTTGCAGGTGTTTTCTGGAGTAGGAGCTGGTTTGGCCTATCTAA
TAAGA

Alignment

ORF - retro_ogar_2494 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 75.41 %
• Parental protein coverage: 69.14 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  EEMEAPAADAIMSPEDELDGYEPEPLGKRPAVLPLLELVGEASNGPSTDGSLPSTPPPAEEEEDELYRQS
          .EMEA.AA.AI.SPE..L..Y.PE.L.K.P.VL.LLE.V.EA.N..S.DGSLPST..PAEEE.DELY.QS
Retrocopy DEMEAHAANAIKSPEGKLATYKPESLRKQPEVLHLLEFVSEAGNRLSIDGSLPSTSAPAEEE-DELYWQS

Parental  LEIISRYLREQATGAKDAKPMGRAGAASRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSR
          LEIISRYL.EQ.TG.KDAKPMGRAG..SRK.LETLR.VGD.VQ.NH..AF.GM..KLDIK..DDV.SLSR
Retrocopy LEIISRYLWEQVTGTKDAKPMGRAGGTSRKVLETLRHVGDEVQCNHKMAFRGMFCKLDIKTGDDVRSLSR

Parental  VMVHVFSDGVTNWGRIVTLISFGAFVAKHLKSINQESCIEPLAESITDVLVRTK-RDWLVKQRGWDGFVE
          V.VHVF..GVTNW...VTLISFG.FVAKHLK.INQESCIEPLAE.I..VLVRTK.RDWLVKQ.GWDGFVE
Retrocopy VRVHVFGYGVTNWDSVVTLISFGGFVAKHLKTINQESCIEPLAENISGVLVRTK>RDWLVKQQGWDGFVE

Parental  FFHVEDLEGGIRNVLLAFAGV-AGVGAGLAYLIR
          FFH.EDL...IRNVLLAFAGV..GVGAGLAYLIR
Retrocopy FFHLEDLQSSIRNVLLAFAGV>SGVGAGLAYLIR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_2494 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 2 parental genes, and 5 retrocopies.

Species	Parental gene accession	Retrocopies number
Otolemur garnettii	ENSOGAG00000016421	4 retrocopies	retro_ogar_1048, retro_ogar_2493, retro_ogar_2494 , retro_ogar_3400,
Oreochromis niloticus	ENSONIG00000006658	1 retrocopy	retro_onil_27,