RetrogeneDB ID: retro_ptro_1191

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 17:64298132..64298614(+)
• Located in intron of: ENSPTRG00000009555

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: DCTN6
• Ensembl ID: ENSPTRG00000020134
• Aliases: None
• Description: None

Sequence

>retro_ptro_1191
GGAACTCGGACAGCGATCCATCCTAAAGCACAAATTATTGCGGAAGCCGGGCCAATAGTGATTGGCAAAGGGAACCTGAC
AGAAGAACAGGCCCTTATCATAAATGCTTCCTCGGATAATGTCACTCTTGACACTGGAGATCCAGAACCAAAACCTATGA
TCATTGGCACCAATAATGTGTTTAAAGTTGGCGTCATTCCCAAGCCATGGAGATGGGAGATAATAATGTCATTGAATTAA
AAGTGTATGTAGGCAGAAATCTAATATTGACAAGTGGCTGTCTCACTGGCGCTTGTTGCAACCTAAACACTTTTGAAGTC
ATCCCGGAGAATACGGTGATCTATGGTGCAGACTGCCTTTGTTGGGTGCAGGCTGAGCGACCGCAGCCTCAGACACTACA
GCTGGATTTCTTGATGAAAATCTTGCCAAATTACCACCACCTAAAGAAGACTACCAAAGGAAGCTCAACTCCAGTAAAGA
AC

Alignment

ORF - retro_ptro_1191 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.19 %
• Parental protein coverage: 84.74 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  GPRTVIHPKARIIAEAGPIVIGEGNLIEEQALIINAYPDNITPDTEDPEPKPMIIGTNNVFEVGC-YSQA
          G.RT.IHPKA.IIAEAGPIVIG.GNL.EEQALIINA..DN.T.DT.DPEPKPMIIGTNNVF.VG...SQA
Retrocopy GTRTAIHPKAQIIAEAGPIVIGKGNLTEEQALIINASSDNVTLDTGDPEPKPMIIGTNNVFKVGV<HSQA

Parental  MKMGDNNVIESKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVIYGADCLRRVQTERPQPQTLQLDFLM
          M.MGDNNVIE.K.YVGRN.ILTSGC..GACCNLNTFEVIPENTVIYGADCL..VQ.ERPQPQTLQLDFLM
Retrocopy MEMGDNNVIELKVYVGRNLILTSGCLTGACCNLNTFEVIPENTVIYGADCLCWVQAERPQPQTLQLDFLM

Parental  KILPNYHHLKKTMKGSSTPVKN
          KILPNYHHLKKT.KGSSTPVKN
Retrocopy KILPNYHHLKKTTKGSSTPVKN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	22.56 RPM
SRP007412_cerebellum	0.07 RPM	23.09 RPM
SRP007412_heart	0.12 RPM	29.44 RPM
SRP007412_kidney	0.03 RPM	20.92 RPM
SRP007412_liver	0.00 RPM	18.33 RPM
SRP007412_testis	0.11 RPM	18.65 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_1191 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_1191 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_1191 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1780
Gorilla gorilla	retro_ggor_2236
Macaca mulatta	retro_mmul_1241

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Parental genes homology:

Parental genes homology involve 17 parental genes, and 23 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000001497	1 retrocopy	retro_amel_1860,
Canis familiaris	ENSCAFG00000006518	1 retrocopy	retro_cfam_2154,
Choloepus hoffmanni	ENSCHOG00000002554	3 retrocopies	retro_chof_1387, retro_chof_390, retro_chof_71,
Cavia porcellus	ENSCPOG00000011021	2 retrocopies	retro_cpor_1437, retro_cpor_706,
Echinops telfairi	ENSETEG00000012307	2 retrocopies	retro_etel_1571, retro_etel_1652,
Felis catus	ENSFCAG00000000133	1 retrocopy	retro_fcat_113,
Homo sapiens	ENSG00000104671	1 retrocopy	retro_hsap_1780,
Gorilla gorilla	ENSGGOG00000013074	1 retrocopy	retro_ggor_2236,
Myotis lucifugus	ENSMLUG00000028330	2 retrocopies	retro_mluc_1616, retro_mluc_2026,
Macaca mulatta	ENSMMUG00000013735	1 retrocopy	retro_mmul_1241,
Monodelphis domestica	ENSMODG00000019010	1 retrocopy	retro_mdom_1260,
Nomascus leucogenys	ENSNLEG00000011906	2 retrocopies	retro_nleu_1311, retro_nleu_2969,
Oryctolagus cuniculus	ENSOCUG00000010968	1 retrocopy	retro_ocun_917,
Ochotona princeps	ENSOPRG00000005061	1 retrocopy	retro_opri_950,
Pan troglodytes	ENSPTRG00000020134	1 retrocopy	retro_ptro_1191 ,
Tarsius syrichta	ENSTSYG00000013306	1 retrocopy	retro_tsyr_893,
Tursiops truncatus	ENSTTRG00000012439	1 retrocopy	retro_ttru_780,