RetrogeneDB ID: retro_chof_2446

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_7640:8150..9211(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PARP2
• Ensembl ID: ENSCHOG00000007172
• Aliases: None
• Description: poly (ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:272]

Sequence

>retro_chof_2446
CCAGAATCACAGCTAAGTCTTCAGTTCCAGGAGCTGATAAAGTTGATTTGTAATGCCCAGGCCATGGAAGAAATGATGGC
AGAAATGAAGTATGATACCAAAAAAGCCCTGCTTGGGAAGTTGACAGTGGCGCAAATTAAGGCAGGTTACCAGTCTCTTG
AGAAGATCGAGGATTGTATTCGGACTGGCTGGCATGGACGAACTCTCATAGAAGCATGCAATGAATTCGACACCAGGATC
CCACATGATTTTGGACTCCATGTCCCTCCATTAATCTGAACAGAAAAAGAACTGTCTGAAAAAGTGCAACTACTAGAGAT
ATTGGGAGACATTGAAATTGCCATTAAGCTGGTGAAGACAGAACTGCAAAGCTCAGAACACCCACTGGACCAACACTATA
GAAACCTGCATTGTGCCTTGCACCCTCTAGACCATGCAAGTCATGAGTTCAAAGTGATTTCACAGTACCTGCAGTCTACC
CATGCTCCCACACACAACGACTATACCATGACCTTGCTGGATGTTTTTGAAGTAGAGAAGGAGGGTGAGAAAGAAGCCTT
CAGAGAGGACCTTCATAACAGGATGTGGCTATGGCATGGTTCCAGGTTGAGTAACTGGGTGGGAATCCTGAGCCACAGGC
TTCGAAATGCCCCATCTGAGGCCCCCATCACAGGTTACATGTTTGGAAAAGGAATCTACTTTGCTGACATGTCTTCCAAG
AGTGCCAATTACTGCTTTGCCTCTTGCCTAAAGGATACAGGACTGCTGCTCTTATCAGAGGTAGCTTTAGGTCAGTGTAA
TGAACTTCTAGATCCAATCATGAGGCAGAAGGGTTACTTCAGGGCAAACACAGCACCAAGGGGCTGGGCAAGATGGCTCC
CAGCCCTGCCTGTTTTATCACCCTAAATGGGAGTACGGTACCCTTAGGACATGCAAATGACACAGGAATTCTGAATCCAG
AGGGTTATACCCTTAACTACAATGAATTTATCATCTACAACCCCAACTAAGTCTGTATGCAGTATCTTCTAAAGGTTCAG
TTTAATTTCCTGCAGTTGTGG

Alignment

ORF - retro_chof_2446 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 90.7 %
• Parental protein coverage: 60.79 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  PESQLDLRVQELIKLICNVQAMEEMMVEMKYDTKKAPLGKLTVAQIKAGYQSLKKIEDCIRSR-HGRALM
          PESQL.L..QELIKLICN.QAMEEMM.EMKYDTKKA.LGKLTVAQIKAGYQSL.KIEDCIR...HGR.L.
Retrocopy PESQLSLQFQELIKLICNAQAMEEMMAEMKYDTKKALLGKLTVAQIKAGYQSLEKIEDCIRTGWHGRTLI

Parental  EACNEFYT-IPHDFGLRVPPLIQTEKELSEKVQLLEALGDIEIAIKLVKTELQSSEHPLDQHYRNLHCAL
          EACNEF.T.IPHDFGL.VPPLI.TEKELSEKVQLLE.LGDIEIAIKLVKTELQSSEHPLDQHYRNLHCAL
Retrocopy EACNEFDTRIPHDFGLHVPPLI*TEKELSEKVQLLEILGDIEIAIKLVKTELQSSEHPLDQHYRNLHCAL

Parental  RPLDHASREFKVISQYLQSTHAPTHNDYTMTLLDVFEVEKEGEKEAFREDLHNRMLLWHGSRLSNWVGIL
          .PLDHAS.EFKVISQYLQSTHAPTHNDYTMTLLDVFEVEKEGEKEAFREDLHNRM.LWHGSRLSNWVGIL
Retrocopy HPLDHASHEFKVISQYLQSTHAPTHNDYTMTLLDVFEVEKEGEKEAFREDLHNRMWLWHGSRLSNWVGIL

Parental  SHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKDTGLLLLSEVALGQCNELLE-ANHEAEGL
          SH.LR.AP.EAPITGYMFGKGIYFADMSSKSANYCFAS.LKDTGLLLLSEVALGQCNELL...NHEAEGL
Retrocopy SHRLRNAPSEAPITGYMFGKGIYFADMSSKSANYCFASCLKDTGLLLLSEVALGQCNELLD<SNHEAEGL

Parental  LQGKHSTKGLGKMAPSPACFITLNGSTVPLGPASDTGILNPEGYTLNYNEFIVYNPNQVRMRYLLKVQFN
          LQGKHSTKGLGKMAPSPACFITLNGSTVPLG.A.DTGILNPEGYTLNYNEFI.YNPN.V.M.YLLKVQFN
Retrocopy LQGKHSTKGLGKMAPSPACFITLNGSTVPLGHANDTGILNPEGYTLNYNEFIIYNPN*VCMQYLLKVQFN

Parental  FLQLW
          FLQLW
Retrocopy FLQLW

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2446 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 1 parental gene, and 1 retrocopy.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000007172	1 retrocopy	retro_chof_2446 ,