RetrogeneDB ID: retro_ggor_1588

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 22:1312848..1313482(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: TERF2IP
• Ensembl ID: ENSGGOG00000005519
• Aliases: None
• Description: None

Sequence

>retro_ggor_1588
CGGTCCCTGAAGCCCCCGCGGGGCCAGGAGCACGAGCACTTGCCAGGGGACGCCTGGGGCGCCCCTCCTCCCAGAAGCTC
CCGCGGAAGACTGGAGCAGGCCACCGGGCTGCGGATAATGGGAACCACAGAGTGCGAGAACTCCACATCGGCCTGAAGGA
AGAGCATGTGAAGGTAGAAATCCAGGAGAGTGAAGAAGCGCTGTAAAAGATGCTTGCAGAAGCCACCCGGGGATTGGAGG
AGGTTGTGGTGGATGAGAGCCCTGATTTGGAAATACATTTAACAATGTGTGATGAGGATCCCCCACGCCTGAGGAAGACT
CAGAAACACAGCCTCATCAGGAAGAAGAAGAAGAAGAAGAAGAAACAGTTTCTCCACTGGAGGTGGGAGCTGCCATTATG
ATGATTCCGCAGTTAATGGAGAAGTTTAACTTGGATCTATCAACAGTTACACAGGCCTTCCTAAAGAATAGTGGCGAGCT
GGAGGCTGTTTCCTCCTTCATAGCGTGCGGTCAGAGAGCTGATGGATAACCCATTTGGTCCCAACAAGATGACATAGGTT
TGTAAAAAGATGATGGGGATAACAGAGTGGCATTGGTCAAAAAATTTGGTGCTCAGAATATAGCTCAGAGGATT

Alignment

ORF - retro_ggor_1588 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 69.12 %
• Parental protein coverage: 53.13 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  RYLKHLRGQEHKYLLGDAPVSP-SSQKLKRKAEEDPEAADSG-EPQNKRTPDLPE-EEYVKEEIQENEEA
          R.LK..RGQEH..L.GDA...P.SSQKL.RK......AAD.G.EPQ..RTP..PE.EE.VK.EIQE.EEA
Retrocopy RSLKPPRGQEHEHLPGDAWGAP<SSQKLPRKTGAGHRAADNG<EPQSARTPHRPE>EEHVKVEIQESEEA

Parental  VKKMLVEATREFEEVVVDESPPDFEIHITMCDDDP-PTPEEDSETQPDEEEEEEEEKVSQP-EVGAAIKI
          ..KML.EATR..EEVVVDES.PD.EIH.TMCD.DP.PTPEEDSETQP.............P.EVGAAI..
Retrocopy L*KMLAEATRGLEEVVVDES-PDLEIHLTMCDEDP<PTPEEDSETQPHQXXXXXXXXTVSPLEVGAAIMM

Parental  IRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADGYPIWSRQDDIDLQKDDEDTREALVKKFGA
          I.QLMEKFNLDLSTVTQAFLKNSGELEA.S.F.A.GQRADG.PIWS.QDDI.L.KDD.D.R.ALVKKFGA
Retrocopy IPQLMEKFNLDLSTVTQAFLKNSGELEAVSSFIACGQRADG*PIWSQQDDIGL*KDDGDNRVALVKKFGA

Parental  QNVARRI
          QN.A.RI
Retrocopy QNIAQRI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	168.13 RPM
SRP007412_cerebellum	0.35 RPM	126.90 RPM
SRP007412_heart	0.22 RPM	13.20 RPM
SRP007412_kidney	0.04 RPM	36.23 RPM
SRP007412_liver	0.08 RPM	26.72 RPM
SRP007412_testis	0.10 RPM	123.80 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1588 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1588 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Pan troglodytes	retro_ptro_1481

---

Parental genes homology:

Parental genes homology involve 3 parental genes, and 3 retrocopies.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000005519	1 retrocopy	retro_ggor_1588 ,
Pan troglodytes	ENSPTRG00000008365	1 retrocopy	retro_ptro_1481,
Tursiops truncatus	ENSTTRG00000001222	1 retrocopy	retro_ttru_999,