RetrogeneDB ID: retro_ggor_2598

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 7:61700640..61701528(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000026627
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: IGLON5
• Ensembl ID: ENSGGOG00000011245
• Aliases: None
• Description: None

Sequence

>retro_ggor_2598
GCGCCCGGGGCCGGGCTCCGGCTTCTCGCCGCCGCCGCCCTGGCCGGCTTGGCCGTCATCAGCCGAGGGCTGCTCTCCCA
GAGCCTGGAGTTCAACTCTCCTGCCGACAACTACACAGTGTGTGAAGGTGACAACGCCACCCTCAGCTGCTTCATGGACG
AGCATGTGACCCGCGTGGCCTGGCTGAACCGCTCCAACATCCTGTACGCCGGCAACGACCGCAGGACCAGCGACCCGCGG
GTGCGGCTGCTCATCAACACCCCCGAGGAGTTCTCCATCCTCATCACCGAGGTGGGGCTCGGCGACGAGGGCCTCTACAC
CTGCTCCTTCCAGACCCGCCACCAGCCGTACACCACTCAGGTCTACCTCACTGTCCACGTCCCTGCCCGCGTTGTGAACA
TCTCGTCGCCTGTGACAGTGAATGAGGGGGGTAATGTGAACCTGCTTTGCCTAGCCGTGGGGCGGCCAGAGCCCACGGTC
ACCTGGAGACAGCTCCGAGACGGCTTCACCTCGGAGGGAGAGATCCTGGAGATCTCTGACATCCAGCGGGGCCAGGCCGG
GGAGTATGAGTGCGTGACTCACAACGGGGTTAACTCGGCGCCCGACAGCCGCCGCGTGCTGGTCACAGTCAACTATCCTC
CGACCATCACGGACGTGACCAGCGCCCGCACCGCGCTGGGCTGGACCGCCTCCTGCGCTGCGAAGCCATGGCGGTTCTCC
CGCGGATTTCCAGTGGTATAAGGATGACAGACTGCTGAGCAGCGGCACGGCCGAGGGCCTGAAGGTGCAGACGGAGCGCA
CCCGCTCGATGCTTCTCTTTGCCAACATGAGCGCCGGCATTACGGCAACTATACGTGTTGCGCCGCCAACCGGCTGGGAG
CGTCCAGC

Alignment

ORF - retro_ggor_2598 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 93.67 %
• Parental protein coverage: 92.52 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  APGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYA
          APGA.LRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCF.DEHVTRVAWLNRSNILYA
Retrocopy APGAGLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFMDEHVTRVAWLNRSNILYA

Parental  GNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTV
          GNDR.TSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYL.VHVPAR.VNISSPVTV
Retrocopy GNDRRTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLTVHVPARVVNISSPVTV

Parental  NEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTV
          NEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTV
Retrocopy NEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTV

Parental  NYPPTITDVTSARTALGRAA-LLRCEAMAV-PPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVS
          NYPPTITDVTSARTALG..A.LLRCEAMAV..PADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFAN.S
Retrocopy NYPPTITDVTSARTALGWTA<LLRCEAMAV<SPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANMS

Parental  A-RHYGNYTCRAPGSLENSA
          A.RHYGNYTC.A...L..S.
Retrocopy A<RHYGNYTCCAANRLGASS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.48 RPM	2.59 RPM
SRP007412_cerebellum	0.20 RPM	8.35 RPM
SRP007412_heart	0.06 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.18 RPM
SRP007412_testis	0.31 RPM	0.73 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2598 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2598 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 4 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000142549	1 retrocopy	retro_hsap_3857,
Gorilla gorilla	ENSGGOG00000011245	1 retrocopy	retro_ggor_2598 ,
Pongo abelii	ENSPPYG00000010315	1 retrocopy	retro_pabe_3051,
Pan troglodytes	ENSPTRG00000011377	1 retrocopy	retro_ptro_2628,