RetrogeneDB ID: retro_ggor_27

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 16:35044614..35045166(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000023193
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSGGOG00000013357
• Aliases: None
• Description: None

Sequence

>retro_ggor_27
ATGATCAAGCTGTTCTCGCTGAAGCAGCAGAAGAAGGAGGAGGAGTCGGCGGGCGGCACCAAGCGCAGCAGCAAGAAGGC
GTCGGCGGCGCAGCTGCGGATCCAGAAGGACATAAACGAGCTGAACCTGCCCAAGACGTGTGATATCAGCTTCTCAGATC
CAGAAGACCTCCTCAACTTCAAGCTGGTCATCTGTCCTGATGAGGGCTTCTACAAGAGTGGGAAGTTTGTGTTCAGTTTT
AAGGTGGGCCAGGGTTACCCGCATGATCCCCCCAAGGTGAAGTGTGAGACAATGGTCTATCACCCCAACATTGACCTCGA
GGGCAACGTCTGCCTTAACATCCTCAGAGAGAACTGGAAGCCAGTCCTTACGATAAACTCCATAATTTATGGCCTGCAGT
ATCTCTACTTGGAGCCCAACCCCGAGGACCCACTGAACAAGAAGGCCGCAGAGGTCCTGCAGAACAACCGGCAGCTGTTT
GAGCAGAACGTGCAGCCCTCCATGCGGGGTGGCTACATAGGCTCCACCTACTTCGAGCGCTGCCTGAAATAG

Alignment

ORF - retro_ggor_27 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 96.17 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLVICPDEGF
          MIKLFSLKQQKKEEESAGGTK.SSKKASAAQLRIQKDINELNLPKTCDISFSDP.DLLNFKLVICPDEGF
Retrocopy MIKLFSLKQQKKEEESAGGTKRSSKKASAAQLRIQKDINELNLPKTCDISFSDPEDLLNFKLVICPDEGF

Parental  YKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPN
          YKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE.WKPVLTINSIIYGLQYL.LEPN
Retrocopy YKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRENWKPVLTINSIIYGLQYLYLEPN

Parental  PEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCLK
          PEDPLNK.AAEVLQNNR.LFEQNVQ.SMRGGYIGSTYFERCLK
Retrocopy PEDPLNKKAAEVLQNNRQLFEQNVQPSMRGGYIGSTYFERCLK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.34 RPM	72.03 RPM
SRP007412_cerebellum	0.51 RPM	40.26 RPM
SRP007412_heart	0.22 RPM	31.14 RPM
SRP007412_kidney	0.00 RPM	22.24 RPM
SRP007412_liver	0.08 RPM	11.58 RPM
SRP007412_testis	0.62 RPM	26.42 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_27 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_27 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1677

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 6 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000130725	1 retrocopy	retro_hsap_1677,
Gorilla gorilla	ENSGGOG00000010709	3 retrocopies	retro_ggor_1518, retro_ggor_1519, retro_ggor_1930,
Gorilla gorilla	ENSGGOG00000013357	1 retrocopy	retro_ggor_27 ,
Mus musculus	ENSMUSG00000005575	1 retrocopy	retro_mmus_2868,