RetrogeneDB ID: retro_ggor_2701

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 8:17810061..17810411(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000023371
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: FAM175A
• Ensembl ID: ENSGGOG00000005818
• Aliases: None
• Description: None

Sequence

>retro_ggor_2701
AATAGCATTACTGATTCCCAAATAGATGATGTTGAAGTTGTTTATACAATTGACATTCAGAAATATATTCCATGCTATCA
GTTTTTTAGTTTTTATGATTCTTCAGGTGAAGTAAATGAGCAAGCACTGAGGAAAATATTATCAAATTCACAAAGAATGT
GGTAGGTTGGTACAAATTCCATCGCCATTCAGATCAGATCATGACATTTAGAGAGAGGCTGCTTCACAAAAACTTGCAGG
AGCATTTTTCAAACCAAGACCTTGTTTTTCTGCTATGAACACCAAGTATAATAACAGAAAGCCGCTCTACTCATCGACTG
GAACATGCCTTATATAAACCTCGAAAAGGA

Alignment

ORF - retro_ggor_2701 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.83 %
• Parental protein coverage: 52. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  NSITDSQMDDVEVVYTIDIQKYIPCYQLFSFYNSSGEVNEQALKKILSNVK-KNVVGWYKFRRHSDQIMT
          NSITDSQ.DDVEVVYTIDIQKYIPCYQ.FSFY.SSGEVNEQAL.KILSN...KNVVGWYKF.RHSDQIMT
Retrocopy NSITDSQIDDVEVVYTIDIQKYIPCYQFFSFYDSSGEVNEQALRKILSNSQ<KNVVGWYKFHRHSDQIMT

Parental  FRERLLHKNLQEHFSNQDLVFLLLTPSIITESCSTHRLEHSLYKPQKG
          FRERLLHKNLQEHFSNQDLVFLL.TPSIITES.STHRLEH.LYKP.KG
Retrocopy FRERLLHKNLQEHFSNQDLVFLL*TPSIITESRSTHRLEHALYKPRKG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.53 RPM
SRP007412_cerebellum	0.00 RPM	0.67 RPM
SRP007412_heart	0.00 RPM	0.22 RPM
SRP007412_kidney	0.20 RPM	1.39 RPM
SRP007412_liver	0.08 RPM	0.50 RPM
SRP007412_testis	1.14 RPM	12.22 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2701 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2701 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 3 parental genes, and 4 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000013241	1 retrocopy	retro_chof_2580,
Gorilla gorilla	ENSGGOG00000005818	1 retrocopy	retro_ggor_2701 ,
Macaca mulatta	ENSMMUG00000015357	2 retrocopies	retro_mmul_1499, retro_mmul_2320,