RetrogeneDB ID: retro_ggor_2851

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 9:39304027..39305157(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ARMC8
• Ensembl ID: ENSGGOG00000023535
• Aliases: None
• Description: None

Sequence

>retro_ggor_2851
AAGAGAGTTAAAGGAGCTGAGACACTTGCCTATCTGATTGAACCAGATATTGAGCTACAGAGAATCGCTAGTGTAACTGA
TCACCTCATCGTCATGTTTGCTGACTATTTCAAGTATCCCAACTCATTGAGTGCCATCACTGATAGTAAAAGGCTTGATC
ATGATTTAAAACATGCTCATGAACTCTGCCAGGCTGCATTCAATCTCTACGACTCTCTTAGAGCAAATGATGAAGACATT
CAGAAGAAAAGCCCTGAGACTGAAAATATGATGGACTGAATTGTGACTGGCTTGTCTGAGTCTAGTGTCAAGGTGCGGTT
ACCTGCTGTCAGATGTTTGCACCGTTTATCCAGATCTGTGCAGCAGCTTCAAAACAGTTTCTAGGATCACACTCTGTGAA
AACCTTTAATGAAGGTTTTACAAAATGCACCAGATGAAATCCTAGTAGCAGCATCTTCCATGGTATATAATCTTCTTGAA
TTTTCTCCAAGGAAAGAGTCAATTTTAAAATCAGGAGTTGTAAAGCTACTTTGTGGATTAACCCAGAGTGAAAATCCTGC
TTTATAAGTGAGCAGAATTTGGGCTTTAATGAATATGGCATTTCAGGCTGAACAAAAAATAAAAGCAGACATGTTACAAA
GCTTGAGTACTGAACAGCTATTCTGGTTATTGTCAGATTCAGATTTGAATGTGCTGATGAAGACACTGGGACTTCTTAGA
AATCTCCTCTTGACCTGGCTTCATATAATAAAATAATGAGTACTCATGGAAAGCAAATTATGCAAGCTGTCATCCTTATT
CTGGAAGGGGAACATAACTTTAAGGTCAAAGAGTAGATACTGTGCATCTTAGCCAATATAAAAGATGAGACAACAGCAAA
AGAATGTATTATGACCAATGATGATATCCTTCAGAAAATCAAATATTACATGGACAATTCAAATGTCAAACTGCAGCTTC
CAGCTATGTTTTGTATATCAAACCTCATATGGAATGAAGAGGAAGGTTCACAAGAATGCCAGGATAAATTATGAGACATG
GGCATCATAGATATTCTACATAAACTGAGTCAGCCACCAGATTCAGACCTTTGTGACAAGGCAAAGATGGCACTGCAGCA
GTACCTGGCA

Alignment

ORF - retro_ggor_2851 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.38 %
• Parental protein coverage: 56.17 %
• Number of stop codons detected: 6
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  ERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLY
          .RV.GAETLAYLIEPD.ELQRIAS.TDHLI.M.ADYFKYP.S.SAITD.KRLDHDLKHAHEL.QAAF.LY
Retrocopy KRVKGAETLAYLIEPDIELQRIASVTDHLIVMFADYFKYPNSLSAITDSKRLDHDLKHAHELCQAAFNLY

Parental  ASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVL
          .SL.ANDEDI.KK..ETENMMD.IVTGLSESSVKVRL.AVRCLH.LSRSVQQL..SF.DH...KPLMKVL
Retrocopy DSLRANDEDIQKKSPETENMMD*IVTGLSESSVKVRLPAVRCLHRLSRSVQQLQNSF*DHTL*KPLMKVL

Parental  QNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKA
          QNAPDEILV.ASSM..N.LLEFSP.KE.IL.SG.V.LLCGLTQSENPAL.V..IWALMNMAFQAEQKIKA
Retrocopy QNAPDEILVAASSMVYN-LLEFSPRKESILKSGVVKLLCGLTQSENPAL*VSRIWALMNMAFQAEQKIKA

Parental  DILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHI-DKIMSTHGKQIMQAVTLILEGEHNIEVKE
          D.L.SLSTEQLF.LLSDSDLNVLMKTLGLLRNLL.T..HI..KIMSTHGKQIMQAV.LILEGEHN..VKE
Retrocopy DMLQSLSTEQLFWLLSDSDLNVLMKTLGLLRNLLLTWLHI<NKIMSTHGKQIMQAVILILEGEHNFKVKE

Parental  QTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMG
          ..LCILANI.D.TTAK..IMTNDDILQKIKYYM..S.VKLQL.AMFCISNLIWNEEEGSQE.QDKL.DMG
Retrocopy *ILCILANIKDETTAKECIMTNDDILQKIKYYMDNSNVKLQLPAMFCISNLIWNEEEGSQECQDKL*DMG

Parental  IVDILHKLSQSPDSNLCDKAKMALQQYLA
          I.DILHKLSQ.PDS.LCDKAKMALQQYLA
Retrocopy IIDILHKLSQPPDSDLCDKAKMALQQYLA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	29.78 RPM
SRP007412_cerebellum	0.20 RPM	54.17 RPM
SRP007412_heart	0.00 RPM	4.91 RPM
SRP007412_kidney	0.16 RPM	23.02 RPM
SRP007412_liver	0.16 RPM	14.14 RPM
SRP007412_testis	0.21 RPM	34.81 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2851 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2851 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4253

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 5 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000114098	1 retrocopy	retro_hsap_4253,
Gorilla gorilla	ENSGGOG00000023535	1 retrocopy	retro_ggor_2851 ,
Macaca mulatta	ENSMMUG00000021285	1 retrocopy	retro_mmul_1142,
Pongo abelii	ENSPPYG00000014140	2 retrocopies	retro_pabe_3384, retro_pabe_3385,