RetrogeneDB ID: retro_ggor_3022

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: X:62755115..62756507(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000024404
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: FRMD8
• Ensembl ID: ENSGGOG00000014773
• Aliases: None
• Description: None

Sequence

>retro_ggor_3022
ATGGACGGGACGGAAGGCAGTGTCGGGCAGCCCGGCCCCACTGAGCGGTCCCACCGAAGCAGCGTGTCCTCCGTGGGAGC
CCGAGCAGCTGACGTGCTGGTATACCTGGCGGATGACACGGTGGTGCCCCTGGCTGTGGAGAACCTGCCTTCGCTCCGTG
CCCATGAGCTGCACTGCGCCATCGGCGAGGTCCTGCAGCTTCCGGACATCGCCCTGGATGTCTTCGCGCTCTGGCTGGTT
TCCCCTCTGCTGGAGGTGCAGCTGAAACCCAAGAACCAGCCCTACAAGCTGGAACGCCAGTGGCCGGAGCTGCTGCTGCG
CTTCACCAGTGCCCCGGACGACGACGTGGCCATGGATGAGCCTTTCCTGCAGTTCCGAAGGAACGTGTTCTTCCCAAAGG
AGCGGGAGCTCCAGATCCCCGACGAGGAGGTCCTGCGGCTGCTCTATGAGGAGGCCAAGGGCAACGTGCTGGCTGCACGG
TACCTGTGCGACGTTGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAGCTCGTACCCTACCAGCCCGACTG
GCCGGCAGCCTGCGACCTGAGGGAGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGCCAGGGTCTCTTTG
CTGCCCTCCGGGGCCGTGGGGCCAGGGCCGGGCCGGGTGAGCAGGGCCTGCTGAACGCCTACCGCGAGGTGCAGGAGGTC
AGCAGCGACGGCGGGTGTGAGGCCGCCCTGGGCACCCACTACCGCGCCTACCTCCTCAAGTGCCACAAGCTGCCCTTCTA
TGGGTGTGCCTTCTTCCACGGTGAGGTTGACAAGCCAGCCCAAGGCTTTTTGCACCGGGGTGGGCGCAAATCAGTTTCTG
TGGCCATCAGTCTGGAAGGTGTGCACGTCGTCGACAGCAGAGAGAAGCACGTCCTGCTGGGCCTGCGCTTCCAGGAGCTG
TCGTGGGACCACACCTCCCCTGAGGAGGAAGAGCCCATCCTGTGGCTGGAGTTCGACAGGAACAGCGGGGGCACACCTGT
CAACAAGCTCCTCAAGATCTACTCCAAGCAGGCTGAACTGATGAGCAGCCTCATTGAGTACTGCATCGAACTGAGCCAGG
CGGCGGAGCCCGCAGGCCCCCAGGACAGTGCAACTGGCTCGCCCTCAGACCCCAGCTCCTCGCCGGCTCCTGTTCAGCGC
CCCAAGCTGCGGAGGCAGGGGAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACCATCGAATACGTGGAGGACGGCAA
GGGGATCAGGCGAGTGAAAACGAAGAGCACCACGTCCTTCTTCAGCCGGCAGCTGTCCTTGGGCCAGGGGAGCTACACCG
TGGTGCAGCCCAGCGACAGCCTGGAGCAGGGC

Alignment

ORF - retro_ggor_3022 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 93.53 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDI
          MDGTEGS.GQPGP.ERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSL.AHELH.A..EVLQLPDI
Retrocopy MDGTEGSVGQPGPTERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLRAHELHCAIGEVLQLPDI

Parental  ALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKRRELQIH
          ALDVFALWLVSPLLEVQLKPK.QPYKL.RQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPK.RELQI.
Retrocopy ALDVFALWLVSPLLEVQLKPKNQPYKLERQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKERELQIP

Parental  DEEVLRLLYEEAKGNVLAVRYPCDVEDCEALGALVCRVQLGPYQPGRLAACDLREKLDSFLPAHLCKRGQ
          DEEVLRLLYEEAKGNVLA.RY.CDVEDCEALGALVCRVQL.PYQP...AACDLREKLDSFLPAHLCKRGQ
Retrocopy DEEVLRLLYEEAKGNVLAARYLCDVEDCEALGALVCRVQLVPYQPDWPAACDLREKLDSFLPAHLCKRGQ

Parental  SLFAALRGRGARAGPGEQGLLNAYRQVQEVGSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPA
          .LFAALRGRGARAGPGEQGLLNAYR.VQEV.SDGGCEAALGTHYRAYLLKCH.LPFYGCAFFHGEVDKPA
Retrocopy GLFAALRGRGARAGPGEQGLLNAYREVQEVSSDGGCEAALGTHYRAYLLKCHKLPFYGCAFFHGEVDKPA

Parental  QGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKL
          QGFLHRGGRK.VSVAISLEGVHV.DSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFD..S.GTPVNKL
Retrocopy QGFLHRGGRKSVSVAISLEGVHVVDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDRNSGGTPVNKL

Parental  LKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSPAPVQRPKLRRQGSVVSSRIQHLSTI
          LKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSPAPVQRPKLRRQGSVVSSRIQHLSTI
Retrocopy LKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSPAPVQRPKLRRQGSVVSSRIQHLSTI

Parental  DYVEDGKGIRRVKPKRTTSFFSRQLSLGQGSYTVVQPGGSLEQG
          .YVEDGKGIRRVK.K.TTSFFSRQLSLGQGSYTVVQP..SLEQG
Retrocopy EYVEDGKGIRRVKTKSTTSFFSRQLSLGQGSYTVVQPSDSLEQG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	6.52 RPM
SRP007412_cerebellum	0.12 RPM	11.19 RPM
SRP007412_heart	0.00 RPM	4.25 RPM
SRP007412_kidney	0.04 RPM	11.65 RPM
SRP007412_liver	0.05 RPM	12.79 RPM
SRP007412_testis	0.10 RPM	23.31 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_3022 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_3022 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 2 parental genes, and 2 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000126391	1 retrocopy	retro_hsap_4844,
Gorilla gorilla	ENSGGOG00000014773	1 retrocopy	retro_ggor_3022 ,