RetrogeneDB ID: retro_ggor_361

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:228482990..228483693(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HSD17B7
• Ensembl ID: ENSGGOG00000011264
• Aliases: None
• Description: None

Sequence

>retro_ggor_361
AATGCTGGGATCATGCCCAGTCCACAGCTAAATGTCAAAACAGTTTTCTTTGGCCTCTTTGGAAGAAAAGTGATTCATAT
GTTCTCCATAGCTGAAGGCCTGCTGACCCAGGATGATAAGATTACTGCTAATGGACTTCAGGAGGTGTTTAAGAACAATG
TCTTTGGCCGTTTTATCCTGATTCAGGAACTGGAGCCTCTCCTCACCACGGTGACAATCCATCTCAACTTACCTGGACAT
CGTCTCGCAATGCAAGGAAATCTAATTTCAACATCAAAGACTTCCAGCCAAGCAAAGGCAAGGAACCCTACAGCTCTTCC
AGATATGCCACTGACCTCCTCAGTGTGGCTTTGAACAGGAACTTCAACCAGCAGGGTATCTATTCCAATGTAGTATGTCC
AGGTAGAGCATTGACCAGTTTGATGTATGGAGTTCTGGCTCCCTTTGTTGGACACTGTTGATGCCACTAATATGGCTGCT
TCGCTTTTTTGCAGATGCATTCACTTTGACACCATACAATGCAATAGAATCACTGGTATGGCTTTTCCAACAAAAGCTCA
AATCTCTCAATCCTCTGATCAAATATCTGAGTGCCACCACTGGCTTTGGAAGAAATTTCATAATGACCCAGAAGATGGAT
CTAGATAAAGACATTGCTGAAAAATTTTATCAAAAGTTACTGGAACTGGAAAAGCATGTTAGG

Alignment

ORF - retro_ggor_361 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.86 %
• Parental protein coverage: 68.91 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  NAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLC-
          NAGIMP.PQLN.K..FFGLF.RKVIHMFS.AEGLLTQ.DKITA.GLQEVF..NVFG.FILI.ELEPLL..
Retrocopy NAGIMPSPQLNVKTVFFGLFGRKVIHMFSIAEGLLTQDDKITANGLQEVFKNNVFGRFILIQELEPLLT<

Parental  HSDNPSQLIWTSSRNARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALT
          H.DNPSQL.WTSSRNARKSNF...DFQ.SKGKEPYSSS.YATDLLSVALNRNFNQQG.YSNV.CPG.ALT
Retrocopy HGDNPSQLTWTSSRNARKSNFNIKDFQPSKGKEPYSSSRYATDLLSVALNRNFNQQGIYSNVVCPGRALT

Parental  NLTYGILPPFI-WTLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYI
          .L.YG.L.PF..WTLLMP.I.LLRFFA.AFTLTPYN..E.LVWLF.QK..SLNPLIKYLSATTGFGRN.I
Retrocopy SLMYGVLAPFV<WTLLMPLIWLLRFFADAFTLTPYNAIESLVWLFQQKLKSLNPLIKYLSATTGFGRNFI

Parental  MTQKMDLDEDTAEKFYQKLLELEKHIR
          MTQKMDLD.D.AEKFYQKLLELEKH.R
Retrocopy MTQKMDLDKDIAEKFYQKLLELEKHVR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	3.69 RPM
SRP007412_cerebellum	0.00 RPM	3.43 RPM
SRP007412_heart	0.00 RPM	0.91 RPM
SRP007412_kidney	0.00 RPM	6.42 RPM
SRP007412_liver	0.00 RPM	13.19 RPM
SRP007412_testis	0.41 RPM	5.91 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_361 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_361 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 2 parental genes, and 2 retrocopies.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000011264	1 retrocopy	retro_ggor_361 ,
Otolemur garnettii	ENSOGAG00000010994	1 retrocopy	retro_ogar_3460,